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Elisa Corti graduated in Biological Science in 2016 at the University of Milan, and two years later she graduated in Neuroscience at the University of Trieste. She moved to Coimbra as one of the 14 Early Stage Researchers within the EU-funded consortium Syn2Psy, where she completing her Ph.D. in Experimental Biology and Biomedicine (PDBEB) under the supervision of Prof. Carlos B. Duarte, Prof. Ramiro Almeida and Prof. Paulo Pinheiro. Her project focuses on understanding how Fragile X messenger ribonucleoprotein (FMRP) regulates synapse physiology, with a particular accent on synaptogenesis and synaptic plasticity. Elisa's field of expertise is broad, ranging from in vitro (preparation of primary hippocampal neurons cultures, imaging of fixed and living samples) to ex vivo experiments (electrophysiology in amygdala and hippocampus, subcellular fractions isolation). Up to now, Elisa published a review article and co-authored a paper published on Molecular Psychiatry, moreover she presented four posters to national and international conferences. Recently she has been awarded a Lab Hero award - Scholar category by HelloBio.
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Identificação

Identificação pessoal

Nome completo
Elisa Corti

Nomes de citação

  • Corti, Elisa

Identificadores de autor

Ciência ID
FC1E-8E58-6C96
ORCID iD
0000-0001-7536-6881

Endereços de correio eletrónico

  • elisacorti@cnc.uc.pt (Profissional)

Moradas

  • Rua Larga, Universidade de Coimbra, pólo I Faculdade de Medicina, 2°andar, lab 206, 3004–504, Coimbra, Coimbra, Portugal (Profissional)

Websites

Domínios de atuação

  • Ciências Médicas e da Saúde

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Italiano (Idioma materno)
Inglês Utilizador independente (B2) Utilizador proficiente (C1) Utilizador independente (B2) Utilizador independente (B2) Utilizador independente (B2)
Português Utilizador elementar (A2) Utilizador elementar (A2) Utilizador elementar (A2) Utilizador elementar (A2) Utilizador elementar (A2)
Formação
Grau Classificação
2019/09 - 2023/09
Em curso
 PDBEB (Doktor (PhD))
Universidade de Coimbra, Portugal
2016/10 - 2018/12
Concluído
 International Master degree in Neuroscience (Master Universitario)
Università degli Studi di Trieste, Itália
"Role of Neuritin in an in vitro model of Rett syndrome: a molecular and cellular approach" (TESE/DISSERTAÇÃO)
 110L
2013/09 - 2016/10
Concluído
 Scienze Biologiche (Bachelor)
Università degli Studi di Milano, Itália
 110L
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2019/09 - Atual Estagiário de Investigação (Investigação) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Projetos

Bolsa

Designação Financiadores
2019/09 - Atual FMRP role in synaptic regulation
EC/H2020/813986/EU
Early Stare Researcher
EU Framework Programme for Research and Innovation Marie Sklodowska-Curie Actions
Em curso
Produções

Publicações

Artigo em revista
  1. Corti, Elisa; Duarte, Carlos B.. Autor correspondente: Duarte, Carlos B.. "FMRP Controls Neuronal Architecture and Synaptic Content of NMDA Receptors in Cultured Hippocampal Neurons". Journal of Molecular Neuroscience (2025):
    Aceite para publicação
  2. Tahiri, Emanuel; Corti, Elisa; Duarte, Carlos B.. "Regulation of synaptic NMDA receptor activity by post-translational modifications". Neurochemical Research (2025):
    No prelo
  3. Masella, Gianluca; Silva, Francisca; Corti, Elisa; Azkona, Garikoitz ; Madeira, Maria Francisca; Tomé, Ângelo R.; Ferreira, Samira G.; et al. Autor correspondente: Santos, Monica. "The amygdala NT3-TrkC pathway underlies inter-individual differences in fear extinction and related synaptic plasticity". Molecular Psychiatry (2024):
    Publicado
  4. Corti, Elisa; Rizzi, Manuela; Duarte, Carlos B.; Osterweil, Emily K.. "The Play-Doh Brain: How Shapeable Neurons Help You Learn and Remember". Frontiers for Young Minds 11 (2024): http://dx.doi.org/10.3389/frym.2023.979294.
    10.3389/frym.2023.979294
  5. Corti, Elisa; Duarte, Carlos B.. Autor correspondente: Duarte, Carlos B.. "The role of post-translational modifications in synaptic AMPA receptor activity". (2023):
    Publicado • https://doi.org/10.1042/BST20220827
Poster em conferência
  1. Corti, Elisa; Pinheiro, Paulo; Almeida, Ramiro D; Duarte, Carlos B.. "Fragile-X-messenger ribonucleoprotein mediates BDNF-induced upregulation of GluN2B-containing NMDA receptors: role in LTP of CA1 synapses". Trabalho apresentado em 5th Flagship School “Neurochemistry of mental illness”, 2024.
  2. Masella, Gianluca; Silva, Francisca; Corti, Elisa; Azkona, Garikoitz ; Madeira, Maria Francisca; Tomé, Angelo R.; Ferreira, Samira G.; et al. "“NT3 TrkC signaling in the brain fear network underlies inter-individual differences in the formation and maintenance of contextual fear extinction memories". Trabalho apresentado em 5th Flagship School “Neurochemistry of mental illness”, 2024.
  3. Corti, Elisa; Pinheiro, Paulo; Almeida, Ramiro D; Duarte, Carlos B.. "Fragile-X-messenger ribonucleoprotein mediates BDNF-induced upregulation of GluN2B-containing NMDA receptors: role in LTP of CA1 synapses". Trabalho apresentado em FENS Forum 2024, 2024.
  4. Duarte, FV; Corti, Elisa; Baptista, Pedro; Duarte, Carlos B.. "BDNF-induced synaptic plasticity: the role of mitochondrial fission". Trabalho apresentado em FENS Forum 2024, 2024.
  5. Masella, Gianluca; Silva, Francisca; Corti, Elisa; Azkona, Garikoiz; Madeira, Maria Francisca; Tomé, Angelo R.; Ferreira, Samira G.; et al. "NT3-TrkC signaling in the brain fear network underlies inter individual differences in the formation and maintenance of contextual fear extinction memories.". 2024.
  6. Corti, Elisa; Masella, Gianluca; Pinheiro, Paulo; Almeida, Ramiro D; Duarte, Carlos B.. "Molecular mechanisms underlying the impairment of LTP in Fmr1 KO mice". Trabalho apresentado em 9th European Synapse Meeting, 2024.
  7. Esteve-Pérez, Rafael; Corti, Elisa; Lanuza, Enrique; Santos, Monica; Duarte, Carlos B.; Herranz-Pérez, Vicente; Agustín-Pavón, Carmen. "IMMATURE NEURONS IN THE OLFACTORY TUBERCLE IN MOUSE MODELS OF X-LINKED NEURODEVELOPMENTAL DISORDERS". Trabalho apresentado em Red Olfativa Espanola, 2024.
  8. Corti, Elisa; Almeida, Ramiro D; Pinheiro, Paulo; Duarte, Carlos B.. "Fragile-X-Mental Retardation Protein mediates BDNF-induced increase of synaptic NMDA receptors content". Trabalho apresentado em ISN/ESN Meeting, 2023.
  9. Masella, Gianluca; Francisca Silva; Corti, Elisa; Madeira, Maria Francisca; Ferreira, Samira G.; Tomé, Angelo R.; Rodrigo A. Cunha; Carlos B. Duarte; Santos, Monica. "NT3/TrkC signaling regulate contextual fear extinction and amygdalar long-term potentiation, with a mechanism dependent on GluN2B subunit of NMDA receptors". Trabalho apresentado em ISN-ESN 2023 Meeting, 2023.
  10. Corti, Elisa; Almeida, Ramiro D; Pinheiro, Paulo; Duarte, Carlos B.. "Fragile-X-Mental Retardation Protein mediates BDNF-induced increase of synaptic NMDA receptors content". Trabalho apresentado em 8th European Synapse Meeting, 2022.
  11. Corti, Elisa; Pinheiro, Paulo; Almeida, Ramiro D; Duarte, Carlos B.. "Fragile-X-Mental Retardation Protein mediates BDNF-induced increase of synaptic NMDA receptors content". Trabalho apresentado em FENS2022, 2022.
  12. Corti, Elisa; Almeida, Ramiro D; Pinheiro, Paulo; Duarte, Carlos B.. "Fragile-X-Mental Retardation Protein mediates BDNF-induced increase of synaptic NMDA receptors content". Trabalho apresentado em 17th Meeting of the Portuguese Society of Neuroscience, 2021.
Recurso online
  1. Corti, Elisa. Ma la libertà di scelta esiste?. 2021. https://www.biologiperlascienza.it/2021/03/ma-la-liberta-di-scelta-esiste/.

Artística / Interpretação

Obra teatral
  1. 2023. LAB 404 - A collective delirium about life in the Lab.
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2024/06 “Molecular mechanisms underlying the impairment of LTP in Fmr1 KO mice Neurodevelopment in health and disease
European Society of Neurochemistry (FENS Forum 2024 satellite event)
2024/05/16 Molecular mechanisms underlying the impairment of LTP in Fmr1 KO mice (Not) knowing what comes next
PDBEB program
2023/05/15 Regulation of synapse dynamics by FMRP: Unravelling the molecular mechanisms underlying Fragile X Syndrome Syn2Psy final meeting
2022/10/19 Regulation of synapse dynamics by FMRP: Unravelling the molecular mechanisms underlying Fragile X Syndrome Syn2Psy Ph.D. day
Syn2Psy (Coimbra, Portugal)
2020/10/05 Regulation of synapse dynamics by FMRP: Unravelling the molecular mechanisms underlying Fragile X Syndrome Syn2Psy Ph.D. day (online)
Syn2Psy

Participação em evento

Descrição da atividade
Tipo de evento 		Nome do evento
Instituição / Organização
2021 - Atual Participation in the European Researchers Night 2021 with different activities, dealing with the relationship between mental health and the environment: a quiz about neuroscience for teenagers and a true/false quiz for children, to show how beneficial nature is to out mental health.
2021/10/20 - 2021/10/23 Participation to the RNA Mechanisms and Brain Disease Conference. "The morphology and complexity of neurons provides unique challenges for the maintenance and modification of the neuronal transcriptome and proteome in the cell body and at synapses. In this meeting, lectures explored how neurons regulate RNA molecules and protein synthesis and how these mechanisms represent vulnerabilities for various neurological diseases."
Conferência
 RNA Mechanisms and Brain Disease Conference
Federation of European Neuroscience Societies, Bélgica
Distinções

Prémio

2024 Lab hero award - Scholar category
Hello Bio Ltd, Reino Unido
2024 Travel grant to attend the 9th European Synapse Meeting
International Brain Research Organization, França
2024 Best Oral Communication
PDBEB, Portugal
2024 Travel grant to attend the FENS2024 and the satellite event
International Society for Neurochemistry, Suiça
2024 Attendee at the 5th flagship school “Neurochemistry of mental illness”
International Society for Neurochemistry, Suiça

Outra distinção

2023 ISN travel grant
International Society for Neurochemistry, Suiça
2021 FCT fellowship
Fundação para a Ciência e a Tecnologia, Portugal