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Elisa Corti graduated in Biological Science in 2016 at the University of Milan, and two years later she graduated in Neuroscience at the University of Trieste. She moved to Coimbra as one of the 14 Early Stage Researchers within the EU-funded consortium Syn2Psy, where she completing her Ph.D. in Experimental Biology and Biomedicine (PDBEB) under the supervision of Prof. Carlos B. Duarte, Prof. Ramiro Almeida and Prof. Paulo Pinheiro. Her project focuses on understanding how Fragile X messenger ribonucleoprotein (FMRP) regulates synapse physiology, with a particular accent on synaptogenesis and synaptic plasticity. Elisa's field of expertise is broad, ranging from in vitro (preparation of primary hippocampal neurons cultures, imaging of fixed and living samples) to ex vivo experiments (electrophysiology in amygdala and hippocampus, subcellular fractions isolation). Up to now, Elisa published a review article and co-authored a paper published on Molecular Psychiatry, moreover she presented four posters to national and international conferences. Recently she has been awarded a Lab Hero award - Scholar category by HelloBio.
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Identification

Personal identification

Full name
Elisa Corti

Citation names

  • Corti, Elisa

Author identifiers

Ciência ID
FC1E-8E58-6C96
ORCID iD
0000-0001-7536-6881

Email addresses

  • elisacorti@cnc.uc.pt (Professional)

Addresses

  • Rua Larga, Universidade de Coimbra, pólo I Faculdade de Medicina, 2°andar, lab 206, 3004–504, Coimbra, Coimbra, Portugal (Professional)

Websites

Knowledge fields

  • Medical and Health Sciences

Languages

Language Speaking Reading Writing Listening Peer-review
Italian (Mother tongue)
English Upper intermediate (B2) Advanced (C1) Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2)
Portuguese Elementary (A2) Elementary (A2) Elementary (A2) Elementary (A2) Elementary (A2)
Education
Degree Classification
2019/09 - 2023/09
Ongoing
 PDBEB (Doktor (PhD))
Universidade de Coimbra, Portugal
2016/10 - 2018/12
Concluded
 International Master degree in Neuroscience (Master Universitario)
Università degli Studi di Trieste, Italy
"Role of Neuritin in an in vitro model of Rett syndrome: a molecular and cellular approach" (THESIS/DISSERTATION)
 110L
2013/09 - 2016/10
Concluded
 Scienze Biologiche (Bachelor)
Università degli Studi di Milano, Italy
 110L
Affiliation

Science

Category
Host institution 		Employer
2019/09 - Current Research Trainee (Research) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Projects

Grant

Designation Funders
2019/09 - Current FMRP role in synaptic regulation
EC/H2020/813986/EU
Early Stare Researcher
EU Framework Programme for Research and Innovation Marie Sklodowska-Curie Actions
Ongoing
Outputs

Publications

Conference poster
  1. Corti, Elisa; Pinheiro, Paulo; Almeida, Ramiro D; Duarte, Carlos B.. "Fragile-X-messenger ribonucleoprotein mediates BDNF-induced upregulation of GluN2B-containing NMDA receptors: role in LTP of CA1 synapses". Paper presented in 5th Flagship School “Neurochemistry of mental illness”, 2024.
  2. Masella, Gianluca; Silva, Francisca; Corti, Elisa; Azkona, Garikoitz ; Madeira, Maria Francisca; Tomé, Angelo R.; Ferreira, Samira G.; et al. "“NT3 TrkC signaling in the brain fear network underlies inter-individual differences in the formation and maintenance of contextual fear extinction memories". Paper presented in 5th Flagship School “Neurochemistry of mental illness”, 2024.
  3. Corti, Elisa; Pinheiro, Paulo; Almeida, Ramiro D; Duarte, Carlos B.. "Fragile-X-messenger ribonucleoprotein mediates BDNF-induced upregulation of GluN2B-containing NMDA receptors: role in LTP of CA1 synapses". Paper presented in FENS Forum 2024, 2024.
  4. Duarte, FV; Corti, Elisa; Baptista, Pedro; Duarte, Carlos B.. "BDNF-induced synaptic plasticity: the role of mitochondrial fission". Paper presented in FENS Forum 2024, 2024.
  5. Masella, Gianluca; Silva, Francisca; Corti, Elisa; Azkona, Garikoiz; Madeira, Maria Francisca; Tomé, Angelo R.; Ferreira, Samira G.; et al. "NT3-TrkC signaling in the brain fear network underlies inter individual differences in the formation and maintenance of contextual fear extinction memories.". 2024.
  6. Corti, Elisa; Masella, Gianluca; Pinheiro, Paulo; Almeida, Ramiro D; Duarte, Carlos B.. "Molecular mechanisms underlying the impairment of LTP in Fmr1 KO mice". Paper presented in 9th European Synapse Meeting, 2024.
  7. Esteve-Pérez, Rafael; Corti, Elisa; Lanuza, Enrique; Santos, Monica; Duarte, Carlos B.; Herranz-Pérez, Vicente; Agustín-Pavón, Carmen. "IMMATURE NEURONS IN THE OLFACTORY TUBERCLE IN MOUSE MODELS OF X-LINKED NEURODEVELOPMENTAL DISORDERS". Paper presented in Red Olfativa Espanola, 2024.
  8. Corti, Elisa; Almeida, Ramiro D; Pinheiro, Paulo; Duarte, Carlos B.. "Fragile-X-Mental Retardation Protein mediates BDNF-induced increase of synaptic NMDA receptors content". Paper presented in ISN/ESN Meeting, 2023.
  9. Masella, Gianluca; Francisca Silva; Corti, Elisa; Madeira, Maria Francisca; Ferreira, Samira G.; Tomé, Angelo R.; Rodrigo A. Cunha; Carlos B. Duarte; Santos, Monica. "NT3/TrkC signaling regulate contextual fear extinction and amygdalar long-term potentiation, with a mechanism dependent on GluN2B subunit of NMDA receptors". Paper presented in ISN-ESN 2023 Meeting, 2023.
  10. Corti, Elisa; Almeida, Ramiro D; Pinheiro, Paulo; Duarte, Carlos B.. "Fragile-X-Mental Retardation Protein mediates BDNF-induced increase of synaptic NMDA receptors content". Paper presented in 8th European Synapse Meeting, 2022.
  11. Corti, Elisa; Pinheiro, Paulo; Almeida, Ramiro D; Duarte, Carlos B.. "Fragile-X-Mental Retardation Protein mediates BDNF-induced increase of synaptic NMDA receptors content". Paper presented in FENS2022, 2022.
  12. Corti, Elisa; Almeida, Ramiro D; Pinheiro, Paulo; Duarte, Carlos B.. "Fragile-X-Mental Retardation Protein mediates BDNF-induced increase of synaptic NMDA receptors content". Paper presented in 17th Meeting of the Portuguese Society of Neuroscience, 2021.
Journal article
  1. Corti, Elisa; Duarte, Carlos B.. Corresponding author: Duarte, Carlos B.. "FMRP Controls Neuronal Architecture and Synaptic Content of NMDA Receptors in Cultured Hippocampal Neurons". Journal of Molecular Neuroscience (2025):
    Accepted
  2. Tahiri, Emanuel; Corti, Elisa; Duarte, Carlos B.. "Regulation of synaptic NMDA receptor activity by post-translational modifications". Neurochemical Research (2025):
    In press
  3. Masella, Gianluca; Silva, Francisca; Corti, Elisa; Azkona, Garikoitz ; Madeira, Maria Francisca; Tomé, Ângelo R.; Ferreira, Samira G.; et al. Corresponding author: Santos, Monica. "The amygdala NT3-TrkC pathway underlies inter-individual differences in fear extinction and related synaptic plasticity". Molecular Psychiatry (2024):
    Published
  4. Corti, Elisa; Rizzi, Manuela; Duarte, Carlos B.; Osterweil, Emily K.. "The Play-Doh Brain: How Shapeable Neurons Help You Learn and Remember". Frontiers for Young Minds 11 (2024): http://dx.doi.org/10.3389/frym.2023.979294.
    10.3389/frym.2023.979294
  5. Corti, Elisa; Duarte, Carlos B.. Corresponding author: Duarte, Carlos B.. "The role of post-translational modifications in synaptic AMPA receptor activity". (2023):
    Published • https://doi.org/10.1042/BST20220827
Online resource
  1. Corti, Elisa. Ma la libertà di scelta esiste?. 2021. https://www.biologiperlascienza.it/2021/03/ma-la-liberta-di-scelta-esiste/.

Artistic / Performance

Theatre play
  1. 2023. LAB 404 - A collective delirium about life in the Lab.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2024/06 “Molecular mechanisms underlying the impairment of LTP in Fmr1 KO mice Neurodevelopment in health and disease
European Society of Neurochemistry (FENS Forum 2024 satellite event)
2024/05/16 Molecular mechanisms underlying the impairment of LTP in Fmr1 KO mice (Not) knowing what comes next
PDBEB program
2023/05/15 Regulation of synapse dynamics by FMRP: Unravelling the molecular mechanisms underlying Fragile X Syndrome Syn2Psy final meeting
2022/10/19 Regulation of synapse dynamics by FMRP: Unravelling the molecular mechanisms underlying Fragile X Syndrome Syn2Psy Ph.D. day
Syn2Psy (Coimbra, Portugal)
2020/10/05 Regulation of synapse dynamics by FMRP: Unravelling the molecular mechanisms underlying Fragile X Syndrome Syn2Psy Ph.D. day (online)
Syn2Psy

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2021 - Current Participation in the European Researchers Night 2021 with different activities, dealing with the relationship between mental health and the environment: a quiz about neuroscience for teenagers and a true/false quiz for children, to show how beneficial nature is to out mental health.
2021/10/20 - 2021/10/23 Participation to the RNA Mechanisms and Brain Disease Conference. "The morphology and complexity of neurons provides unique challenges for the maintenance and modification of the neuronal transcriptome and proteome in the cell body and at synapses. In this meeting, lectures explored how neurons regulate RNA molecules and protein synthesis and how these mechanisms represent vulnerabilities for various neurological diseases."
Conference
 RNA Mechanisms and Brain Disease Conference
Federation of European Neuroscience Societies, Belgium
Distinctions

Award

2024 Lab hero award - Scholar category
Hello Bio Ltd, United Kingdom
2024 Travel grant to attend the 9th European Synapse Meeting
International Brain Research Organization, France
2024 Best Oral Communication
PDBEB, Portugal
2024 Travel grant to attend the FENS2024 and the satellite event
International Society for Neurochemistry, Switzerland
2024 Attendee at the 5th flagship school “Neurochemistry of mental illness”
International Society for Neurochemistry, Switzerland

Other distinction

2023 ISN travel grant
International Society for Neurochemistry, Switzerland
2021 FCT fellowship
Fundação para a Ciência e a Tecnologia, Portugal