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M. Sofia Fernandes obtained her PhD at Imperial College London (London, UK) in Human Reproductive Biology in 2008 and her MSc at Imperial College London in 2003 in Human Reproductive and Developmental Biology (awarded with Distinction). Her work focused on the role and signalling pathways of novel progesterone receptors with impact in female reproduction and pregnancy loss. This 6-year period was fundamental for her internationalization and development of interdisciplinary competences to pursue her research. Following her PhD and over the last years, M. Sofia Fernandes became a PostDoc/Junior Researcher at Instituto de Investigação e Inovação da Universidade do Porto (i3S)/ Instituto de Patologia e Imunologia Molecular da Universidade do Porto (Ipatimup) at the Epithelial Interactions in Cancer Group (EPIC) led by Raquel Seruca. During this period, M Sofia Fernandes also joined Instituto Superior Técnico (IST)-Institute for Systems and Robotics (ISR). In 2023, M. Sofia Fernandes joined, as a Junior Reseracher, the Intercellular Communication and Cancer Group at i3S, led by Professor José Carlos Machado. M. Sofia Fernandes has been interested in the areas of Oncobiology, Applied Cancer Research, Computational Bioimaging and Technological and Translational Research. M. Sofia Fernandes has an h-index of 15 (Scopus), 26 internationally peer reviewed publications: 20 articles in journals, 1 conference paper and 5 book chapters, with 1179 citations by 1044 documents. Specifically, her research has focused on exploring many aspects of epithelial cancers, in particular in unravelling novel cancer biomarkers and developing novel technological strategies for early cancer detection and monitor cancer progression, ultimately assisting patient stratification and therapeutic approaches. M. Sofia Fernandes has also been focusing on Liquid Biopsies and Circulating Tumour Cells (CTCs) and on the development of novel approaches to better isolate and evaluate these cells, with impact in cancer detection and therapeutic strategies. M. Sofia Fernandes is a certified user of the CellSearch (Menarini Silicon Biosystems), the only FDA approved system for the isolation and enumeration of CTCs in metastatic breast, prostate and colorectal cancer. She is also certified for the DEPArray Plus (Menarini Silicon Biosystems), a system to recover individual cells for further analysis, namely CTCs. M. Sofia Fernandes also focused on Cell-ECM interactions and in establishing models for the analysis of phenotypic and molecular features of cancer cells. In addition, M. Sofia Fernandes is involved in developing bioimaging strategies based on machine/deep learning algorithms for several purposes namely lung cancer detection, cell cycle staging at single cell level,and identification of invasive cancer cells based on the cytoskeletal architecture, with impact in cancer research and clinical applications. Her period as a researcher at IST-ISR was fundamental to strengthen her interdisciplinary competences for translational medicine, in which she was involved in the development of novel bioimaging tools. She was also involved in establishing a pipeline that is able to generate a detailed quantitative analysis of a large panel of molecules distributed in distinct compartments of the cell. A collaboration with the International Iberian Nanotechnology Lab (INL) further improved her interdisciplinarity. Along the years, M. Sofia Fernandes has also been investigating novel biomarkers and alternative therapeutic strategies for colorectal cancer focusing on the MAPK and PI3K signalling pathways and involved in better understanding the role of E-cadherin in gastric cancer. During her path, M. Sofia Fernandes has been actively involved in attracting funding, has been reviewer for peer-reviewed scientific journals, disseminated her research at international meetings and communication events; supervised and monitored students and has been involved in several projects.
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Identificação

Identificação pessoal

Nome completo
Sofia Fernandes

Nomes de citação

  • Fernandes, Maria Sofia

Identificadores de autor

Ciência ID
DB12-69EA-4FFB
ORCID iD
0000-0002-5021-3253
Scopus Author Id
9038807900

Domínios de atuação

  • Ciências Naturais - Ciências Biológicas - Biologia Celular
  • Ciências Médicas e da Saúde - Medicina Clínica - Oncologia
  • Ciências Naturais - Ciências Biológicas - Biologia Molecular
  • Ciências Naturais - Ciências Biológicas - Biologia da Reprodução
  • Ciências Naturais - Ciências Biológicas - Bioquímica
  • Ciências da Engenharia e Tecnologias

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2)
Francês Utilizador independente (B2) Utilizador independente (B2) Utilizador independente (B2) Utilizador independente (B2) Utilizador independente (B2)
Espanhol; Castelhano Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1)
Formação
Grau Classificação
2003/11/02 - 2008/08/31
Concluído
 PhD Human Reproductive Biology/ Molecular Endocrinology (Doctor of Philosophy)
Especialização em Human Reproductive Biology/ Molecular Endocrinology
Imperial College London Faculty of Medicine, Reino Unido
"Expression and Role of Putative Membrane Progestin Receptors in Non-Genomic Hormone Actions in the Female Reproductive Tract" (TESE/DISSERTAÇÃO)
 Not applicable
2002/10/01 - 2003/11/01
Concluído
 MSc in Human Reproductive and Developmental Biology (with Distinction) (Master)
Especialização em Human Reproductive and Developmental Biology
Imperial College London Faculty of Medicine, Reino Unido
"Characterization of the Novel Membrane Progestin Receptors alpha and beta in Female Reproductive Tissues" (TESE/DISSERTAÇÃO)
 Distinction
1996/09/18 - 2001/07/25
Concluído
 Biochemistry - Applied Biochemistry Option (BSc)- Pratical Training: 19 out of 20; Last year average mark: 18 out of 20 (Licenciatura)
Especialização em Bioquímica Aplicada
Universidade do Porto Faculdade de Ciências, Portugal
"Study of the Chromosomic Constitution of the Male Germinal Epithelium Cells Isolated from Patients with Conserved Spermatogenesis and with Azoospermia" (TESE/DISSERTAÇÃO)
 14
1995/09 - 1996/06
Concluído
 Ensino Secundário (Ensino secundário)
Especialização em Científico-natural
Escola Secundaria Filipa De Vilhena, Portugal
 18
Percurso profissional

Outros

Categoria Profissional
Instituição de acolhimento 		Empregador
2023/07/15 - Atual Junior Researcher Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
(...)
2022/01/01 - 2023/07/14 Junior Researcher Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
(...)
2019/01/01 - 2021/11/22 Junior Researcher Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
(...)
2018/01/01 - 2018/12/01 Auxiliar Researcher Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal
2016/08/01 - 2017/12/31 PostDoc Researcher Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
(...)
2010/04/01 - 2016/07/31 PostDoc Researcher Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
2008/10/01 - 2010/03/31 PostDoc Researcher Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
2001/09 - 2002/07 Embryologist Universidade do Porto Faculdade de Medicina, Portugal
Universidade do Porto Faculdade de Medicina, Portugal
Projetos

Bolsa

Designação Financiadores
2023/01/01 - 2026/12/31 Cellular architecture deconstructed: Artificial Intelligence to predict cancer invasion (I-CARD)
2022.02665.PTDC
Investigador
Universidade de Lisboa Instituto Superior Técnico, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Associação para a Inovação e Desenvolvimento da FCT
Em curso
2021/03/01 - 2024/02/29 Nuclear biomarkers for predictive prognosis of hereditary diffuse gastric cancer (NICE)
NICE
Investigador
No Stomach for Cancer, Inc, Estados Unidos
Em curso
2017/11/01 - 2023/10/31 Today's Present, Tomorrow's Future on the Study of Germline E-Cadherin Missense Mutations: A Step Foward on Providing Informed Genetic Counceling to Everyone
STOMACH
Investigador
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
Em curso
2018/11/22 - 2021/11/21 Mechano-Dependent Capture of Circulating Tumour Cells: a Cell-ECM Based Approach Coupled With Cancer Specific Glycomarkers (CAPTURE)
POCI-01-0145-FEDER-030383
Investigador
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2016/06/01 - 2019/11/30 Tracing Gastric Cancer Using Quantitative Bioimaging Analysis (TRACE)
PTDC/BBB-IMG/0283/2014
Investigador
Universidade de Lisboa Instituto Superior Técnico, Portugal

Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2010/04/01 - 2016/07/31 Dissecting the EGFR downstream targets predictive of therapy outcome in colorectal cancer patients and assessment of new targeted therapies
SFRH / BPD / 63716 / 2009
Bolseiro de Pós-Doutoramento
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2013/06/01 - 2015/09/30 Mutant E-Cadherin and Novel Interactors in Cancer (MECANIC). The role of mutant E-cadherin-integrin-ECM crosstalk in gastric cancer.
info:eu-repo/grantAgreement/FCT/COMPETE/124283/PT
Investigador Pós-doutorado
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2013/01/01 - 2015/06/30 Molecular mechanisms underlying cancer cell invasion in two cancer disease models, gastric and breast
NORTE-07-0124-FEDER-000022
Investigador Pós-doutorado
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2009/07/01 - 2011/06/30 Tumor Molecular Biomarkers (tissue and serum) to help stratification of colorectal carcinoma patients for anti-EGFR therapies
HealthClusterPortugal-Polo de Competititvidade da Saúde
Investigador Pós-doutorado
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2008/10/01 - 2010/03/31 Criação de um Banco de DNA e RNA acoplado ao Banco de Tecidos e Tumores do H. S. João
BDNA
Bolseiro de Pós-Doutoramento
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
 Universidade do Porto Instituto de Patologia e Imunologia Molecular
Concluído
2003/11/02 - 2008/08/31 Expression and Role of Putative Membrane Progestin Receptors in Non-Genomic Hormone Actions in the Female Reproductive Tract
SFRH/BD/19418/2004
Bolseiro de Doutoramento
Imperial College London Faculty of Medicine, Reino Unido
 Fundação para a Ciência e a Tecnologia
Concluído
Produções

Publicações

Artigo em conferência
  1. Narotamo, Hemaxi; Fernandes, M. Sofia; Miguel Sanches, J.; Silveira, Margarida. "Interphase Cell Cycle Staging using Deep Learning". Trabalho apresentado em 42nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) in conjunction with the 43rd Annual Conference of the Canadian Medicaland Biological Engineering Society, Montréal, 2020.
    Publicado • 10.1109/embc44109.2020.9175583
Artigo em revista
  1. Narotamo, H.; Fernandes, M.S.; Moreira, A.M.; Melo, S.; Seruca, R.; Silveira, M.; Sanches, J.M.. "A machine learning approach for single cell interphase cell cycle staging". Scientific Reports 11 1 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85116364785&partnerID=MN8TOARS.
    10.1038/s41598-021-98489-5
  2. Corso, G.; Montagna, G.; Figueiredo, J.; Vecchia, C.L.; Romario, U.F.; Fernandes, M.S.; Seixas, S.; et al. "Hereditary gastric and breast cancer syndromes related to CDH1 germline mutation: A multidisciplinary clinical review". Cancers 12 6 (2020): 1-25. http://www.scopus.com/inward/record.url?eid=2-s2.0-85086649941&partnerID=MN8TOARS.
    10.3390/cancers12061598
  3. Moreira, A.M.; Pereira, J.; Melo, S.; Fernandes, M.S.; Carneiro, P.; Seruca, R.; Figueiredo, J.. "The Extracellular Matrix: An Accomplice in Gastric Cancer Development and Progression". Cells 9 2 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85091440107&partnerID=MN8TOARS.
    10.3390/cells9020394
  4. Carneiro, Patrícia; Moreira, Ana Margarida; Figueiredo, Joana; Barros, Rita; Oliveira, Patrícia; Fernandes, Maria Sofia; Ferro, Anabela; et al. "S100P is a molecular determinant of E-cadherin function in gastric cancer". Cell Communication and Signaling 17 1 (2019): http://dx.doi.org/10.1186/s12964-019-0465-9.
    10.1186/s12964-019-0465-9
  5. Figueiredo, J.; Melo, S.; Carneiro, P.; Moreira, A.M.; Fernandes, M.S.; Ribeiro, A.S.; Guilford, P.; Paredes, J.; Seruca, R.. "Clinical spectrum and pleiotropic nature of CDH1 germline mutations". Journal of Medical Genetics (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85060236556&partnerID=MN8TOARS.
    10.1136/jmedgenet-2018-105807
  6. Figueiredo, J.; Rodrigues, I.; Ribeiro, J.; Fernandes, M.S.; Melo, S.; Sousa, B.; Paredes, J.; Seruca, R.; Sanches, J.M.. "Geometric compensation applied to image analysis of cell populations with morphological variability: A new role for a classical concept". Scientific Reports 8 1 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85049644419&partnerID=MN8TOARS (2018 IF: 4.0; Q1).
    10.1038/s41598-018-28570-z
  7. Melo, S.; Figueiredo, J.; Fernandes, M.S.; Gonçalves, M.; Morais-De-Sá, E.; Sanches, J.M.; Seruca, R.. "Predicting the functional impact of CDH1 missense mutations in hereditary diffuse gastric cancer". International Journal of Molecular Sciences 18 12 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85038807279&partnerID=MN8TOARS (2017 IF: 3.7; Q1).
    10.3390/ijms18122687
  8. Fernandes, M.S.; Melo, S.; Velho, S.; Carneiro, P.; Carneiro, F.; Seruca, R.. "Specific inhibition of p110a subunit of PI3K: Putative therapeutic strategy for KRAS mutant colorectal cancers". Oncotarget 7 42 (2016): 68546-68558. http://www.scopus.com/inward/record.url?eid=2-s2.0-85014747304&partnerID=MN8TOARS (2016 IF: 5.2; Q1).
  9. Alves, S.; Castro, L.; Fernandes, M.S.; Francisco, R.; Castro, P.; Priault, M.; Chaves, S.R.; et al. "Colorectal cancer-related mutant KRAS alleles function as positive regulators of autophagy". Oncotarget 6 31 (2015): 30787-30802. http://www.scopus.com/inward/record.url?eid=2-s2.0-84945530861&partnerID=MN8TOARS (2015 IF: 5.0; Q1).
    10.18632/oncotarget.5021
  10. Velho, S.; Fernandes, M.S.; Leite, M.; Figueiredo, C.; Seruca, R.. "Causes and consequences of microsatellite instability in gastric carcinogenesis". World Journal of Gastroenterology 20 44 (2014): 16433-16442. http://www.scopus.com/inward/record.url?eid=2-s2.0-84918813931&partnerID=MN8TOARS (2014 IF: 2.4; Q1).
    10.3748/wjg.v20.i44.16433
  11. Carneiro, P.; Figueiredo, J.; Bordeira-Carriço, R.; Fernandes, M.S.; Carvalho, J.; Oliveira, C.; Seruca, R.. "Therapeutic targets associated to E-cadherin dysfunction in gastric cancer". Expert Opinion on Therapeutic Targets 17 10 (2013): 1187-1201. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884582960&partnerID=MN8TOARS (2012 IF: 4.9; Q1).
    10.1517/14728222.2013.827174
  12. Fernandes, M.S.; Carneiro, F.; Oliveira, C.; Seruca, R.. "Colorectal cancer and RASSF family-A special emphasis on RASSF1A". International Journal of Cancer 132 2 (2013): 251-258. http://www.scopus.com/inward/record.url?eid=2-s2.0-84869503619&partnerID=MN8TOARS (2013 IF: 5.0; Q1).
    10.1002/ijc.27696
  13. Figueiral, M.H.; Fonseca, P.; Campos, J.C.; Correia, A.R.; Fernandes, M.S.; Branco, F.J.. "Removable partial denture education in Portugal following the Bologna Process". The European journal of prosthodontics and restorative dentistry 21 3 (2013): 127-134. http://www.scopus.com/inward/record.url?eid=2-s2.0-84891593546&partnerID=MN8TOARS.
  14. Carneiro, P.; Fernandes, M.S.; Figueiredo, J.; Caldeira, J.; Carvalho, J.; Pinheiro, H.; Leite, M.; et al. "E-cadherin dysfunction in gastric cancer - Cellular consequences, clinical applications and open questions". FEBS Letters 586 18 (2012): 2981-2989. http://www.scopus.com/inward/record.url?eid=2-s2.0-84864922992&partnerID=MN8TOARS (2012 IF: 3.6; Q2).
    10.1016/j.febslet.2012.07.045
  15. Paredes, J.; Figueiredo, J.; Albergaria, A.; Oliveira, P.; Carvalho, J.; Ribeiro, A.S.; Caldeira, J.; et al. "Epithelial E- and P-cadherins: Role and clinical significance in cancer; BBA - Reviews on Cancer". Biochimica et Biophysica Acta - Reviews on Cancer 1826 2 (2012): 297-311. http://www.scopus.com/inward/record.url?eid=2-s2.0-84861800037&partnerID=MN8TOARS (2012 IF: 9.0; Q1).
    10.1016/j.bbcan.2012.05.002
  16. Gellersen, B.; Fernandes, M.S.; Brosens, J.J.. "Non-genomic progesterone actions in female reproduction". Human Reproduction Update 15 1 (2009): 119-138. http://www.scopus.com/inward/record.url?eid=2-s2.0-58049218988&partnerID=MN8TOARS (2009 IF: 7.0; Q1).
    10.1093/humupd/dmn044
  17. Fernandes, M.S.; Brosens, J.J.; Gellersen, B.. "Honey, we need to talk about the membrane progestin receptors". Steroids 73 9-10 (2008): 942-952. http://www.scopus.com/inward/record.url?eid=2-s2.0-44549088114&partnerID=MN8TOARS (2008 IF: 2.6; Q3).
    10.1016/j.steroids.2007.12.004
  18. Krietsch, T.; Fernandes, M.S.; Kero, J.; Lösel, R.; Heyens, M.; Lam, E.W.-F.; Huhtaniemi, I.; Brosens, J.J.; Gellersen, B.. "Human homologs of the putative G protein-coupled membrane progestin receptors (mPRa, b, and g) localize to the endoplasmic reticulum and are not activated by progesterone". Molecular Endocrinology 20 12 (2006): 3146-3164. http://www.scopus.com/inward/record.url?eid=2-s2.0-33751500973&partnerID=MN8TOARS (2006 IF: 5.0; Q1).
    10.1210/me.2006-0129
  19. Francis, J.; Rai, R.; Sebire, N.J.; El-Gaddal, S.; Fernandes, M.S.; Jindal, P.; Lokugamage, A.; Regan, L.; Brosens, J.J.. "Impaired expression of endometrial differentiation markers and complement regulatory proteins in patients with recurrent pregnancy loss associated with antiphospholipid syndrome". Molecular Human Reproduction 12 7 (2006): 435-442. http://www.scopus.com/inward/record.url?eid=2-s2.0-33747871430&partnerID=MN8TOARS (2006 IF: 2.8; Q1).
    10.1093/molehr/gal048
  20. Fernandes, M.S.; Pierron, V.; Michalovich, D.; Astle, S.; Thornton, S.; Peltoketo, H.; Lam, E.W.-F.; et al. "Regulated expression of putative membrane progestin receptor homologues in human endometrium and gestational tissues". Journal of Endocrinology 187 1 (2005): 89-101. http://www.scopus.com/inward/record.url?eid=2-s2.0-27644527908&partnerID=MN8TOARS (2005 IF: 3.1; Q2).
    10.1677/joe.1.06242
  21. Sousa, M.; Cremades, N.; Alves, C.; Fernandes, M.S.; Silva, J.; Barros, A.. "Characterization of male germ cells in secretory azoospermia by molecular cytology: maturation arrest,Caracterización citogenética molecular de las células germinales masculinas en la azoospermia secretora: parada de la maduración". Revista Internacional de Andrologia 3 2 (2005): 54-62. http://www.scopus.com/inward/record.url?eid=2-s2.0-77949837766&partnerID=MN8TOARS.
    10.1016/S1698-031X(05)74690-2
Capítulo de livro
  1. Pereira, Joana; Melo, Soraia; Carneiro, Patrícia; Fernandes, Maria Sofia; Figueiredo, Joana; Seruca, Raquel. "Revisiting the Biological and Clinical Impact of CDH1 Missense Variants". In Hereditary Gastric and Breast Cancer Syndrome, 79-97. Springer International Publishing, 2023.
    10.1007/978-3-031-21317-5_6
  2. Fernandes, M.S.; Sanches, J.M.; Seruca, R.. "Targeting the PI3K signalling as a therapeutic strategy in colorectal cancer". In Advances in Experimental Medicine and Biology, 35-53. Alemanha, 2018.
    Publicado • 10.1007/978-3-030-02771-1_4
  3. Ferro, A.; Carvalho, P.; Fernandes, M.S.; Mestre, T.; Sanches, J.M.; Seruca, R.. "Illuminating the cycle of life". In Fluorescence Imaging and Biological Quantification, 201-230. Estados Unidos: Taylor and Francis Press, ISBN 9781498737043; DOI 10.1201/9781315121017, 2018.
    Publicado
  4. Fernandes, M.S.; Ferro, A.; Carneiro, P.; Seruca, R.; Sanches, J.M.. "Quantum dots: Concepts, imaging, and therapeutic applications in cancer". In Fluorescence Imaging and Biological Quantification, 105-118. Estados Unidos: Taylor and Francis Press, ISBN 9781498737043; DOI 10.1201/9781315121017, 2017.
    Publicado
  5. Fernandes, Maria Sofia ; Raquel Seruca; Sergia Velho. "Microsatellite Instability in Colorectal Cancer". In Molecular Pathology: A Practical Guide for the Surgical Pathologist and Cytopathologist, editado por John M. S. Bartlett; Abeer Shaaban; Fernando Schmitt, 119-129. Cambridge University Press, 2015.
    Publicado
Poster em conferência
  1. Vieira, D. F.; Fernandes, Maria Sofia ; Ana Margarida Moreira; Figueiredo, Joana; Seruca, Raquel; Sanches, Joao. "A computational approach for cytoskeletal organization characterization". Trabalho apresentado em SPAOM2023 ¿ Spanish Portuguese Meeting for Advanced Optical Microscopy, 2023.
  2. Vieira, D. F.; Fernandes, Maria Sofia; Ana Margarida Moreira; Figueiredo, Joana; Seruca, Raquel; Sanches, Joao. "Unraveling the cytoskeletal architecture of cancer cells: a novel computational approach". Trabalho apresentado em LARSyS Annual Meeting 2023, 2023.
  3. Fernandes, Maria Sofia ; Joana Figueiredo; Diogo Vieira; Soraia Melo; Ana Margarida Moreira; João Miguel Sanches; Raquel Seruca. "Unraveling new strategies for early detection of invasive cancer cells: A special focus on the nuclear and cytoskeletal architecture". Trabalho apresentado em AACR Annual Meeting 2023, Orlando, Florida, 2023.
  4. Fernandes, Maria Sofia; Figueiredo, J.; Vieira, D. F.; Sanches, Joao; Seruca, R.. "Unravelling new strategies for early detection of invasive cancer cells: a special focus on the nuclear and cytoskeletal architecture". Trabalho apresentado em AACR Annual Meeting 2023, 2023.
  5. Fernandes, Maria Sofia; Figueiredo, Joana; Melo, Soraia; Vieira, Diogo; Moreira, Ana Margarida; Maia, André; Sanches, João Miguel; Seruca, Raquel. Autor correspondente: Fernandes, Maria Sofia. "Unravelling New Strategies for Early Detection of Invasive Cancer Cells: a Focus on the Nuclear Architecture Dynamics". Trabalho apresentado em EACR 2022, 20-23 June 2022 Seville Spain, 28th Congress of the European Association for Cancer Research, 2022.
  6. Hemaxi Narotamo; Fernandes, Maria Sofia ; Ana Margarida Moreira; Raquel Seruca; Margarida Silveira; João Sanches. "In situ cell cycle stage at single cell level within cell populations - EACR-AACR-ASPIC Conference: Tumor Microenvironment, Lisbon, Portugal, 02-04 March 2020". Trabalho apresentado em EACR-AACR-ASPIC Conference: Tumor Microenvironment, 2020.
  7. Fernandes, Maria Sofia ; Ferro, Anabela; Carneiro,Patrícia; Seruca, R; Sanches, J. M.. "Quantum dot-based bioimaging to trace gastric cancer: a new approach to develop novel biomarker quantification tools". Trabalho apresentado em Bioimaging 2016- Disease in Focus, 2016.
  8. Carneiro, P.; Moreira, A.M; Figueiredo, J.; Velho, S.; Vieria, A.; Oliveira, P.; Fernandes, Maria Sofia ; et al. "S100P is a molecular determinant of E-cadherin function in gastric cancer, Gordon Research Conference - Signaling by Adhesion Receptors, USA, June 2016.". Trabalho apresentado em Gordon Research Conference - Signaling by Adhesion Receptors, USA, June 2016., 2016.
  9. Carneiro, P; Moreira, AM; Figueiredo, J; Velho, S; Oliveira, P.; Fernandes, Maria Sofia ; Ferro, A; Oliveira, C.; Carneiro, F. "S100P is a molecular determinant of E-cadherin function in gastric cancer- Second ASPIC International Meeting, IPO Porto, Portugal, 28-29 April 2016". Trabalho apresentado em Second ASPIC International Meeting, IPO Porto, Portugal, 28-29 April 2016., 2016.
  10. Fernandes, Maria Sofia ; Melo, S.; Velho, S.; Mendes, N.; Carneiro, P.; Carneiro, F.; Seruca, R.. "Targeted Inhibition of PI3K p110a as an Alternative Therapeutic Strategy for Colorectal Cancer Patients with KRAS Mutations - Second ASPIC International Meeting, IPO Porto, Portugal, 28-29 April 2016.". Trabalho apresentado em Second ASPIC International Meeting, IPO Porto, Portugal, 28-29 April 2016., 2016.
  11. Alves, S.; Castro, L.; Fernandes, Maria Sofia ; Castro, P.; Priault, M.; Chaves, S.R.; Moyer, M.P.; et al. "Hotspot mutations in the KRAS oncogene function as positive regulators of autophagy in colon. XIII Porto Cancer Meeting-Stem Cells and Cancer; 7-8 May 2015, Porto, Portugal.". Trabalho apresentado em XIII Porto Cancer Meeting-Stem Cells and Cancer, 2015.
  12. Fernandes, Maria Sofia ; Melo, S.; Carneiro, F.; Seruca, R.. "Exploring New Strategies for Colorectal Cancer Therapy: a MAPK- and PI3K-Targeted Approach. Cold Spring Harbor Laboratory Cell Death Meeting held in Cold Spring Harbor Laboratory, NY, United States, 8-12th October 2013.". Trabalho apresentado em Cold Spring Harbor Laboratory Cell Death Meeting held in Cold Spring Harbor Laboratory, NY, United States, 8-12th October 2013., 2013.
  13. Fernandes, Maria Sofia ; Carneiro, F.; Seruca, R.. "Exploring Alternative Therapies for Colorectal Cancer and Identification of Novel Biomarkers Predictive of Therapy Outcome. EACR/IACR Joint Conference on “TheTumour Microenvironment” held in Dublin from 17th to 19th September 2012.". Trabalho apresentado em EACR/IACR Joint Conference on “TheTumour Microenvironment” held in Dublin from 17th to 19th September 2012., 2012.
  14. Krietsch, T.; Fernandes, Maria Sofia ; Losel, R; Huhtaniemi, I; Brosens, J; Gellersen, G.. "Comparative Analysis of the Putative Membrane Progestin Receptor-alpha from Human, Pufferfish and Spotted Seatrout. 40th Annual Scientific Meeting of the European Society for Clinical Investigation, Prague, Czech Republic, 15-18 March.". Trabalho apresentado em 40th Annual Scientific Meeting of the European Society for Clinical Investigation, Prague, Czech Republic, 15-18 March., 2006.
  15. Fernandes, Maria Sofia ; Pierron, V.; Michalovich, D.; Astle, S.; Thornton, S; Peltoketo, H.; Lam, E; et al. "Expression and Regulation of the membrane progestine receptor homologuesin human endometrium and pregnancy tissues. ENDO2005, San Diego, California, USA, 4-7 June 2005". Trabalho apresentado em ENDO2005, San Diego, California, USA, 4-7 June, 2005, 2005.
  16. Krietsch, T.; Fernandes, Maria Sofia ; Huhtaniemi, I.; Brosens, J.; Gellersen, B.. "Subcellular Localization and Functional Analysis of the Putative Human Membrane Receptor human membrane PR-alpha, -beta and -gamma. 4th International Meeting on Rapid Responses to Steroid Hormones. San Diego, California, USA, 28-30 March 2005". Trabalho apresentado em 4th International Meeting on Rapid Responses to Steroid Hormones. San Diego, California, USA, 28-30 March 2005, 2005.
  17. Fernandes, Maria Sofia ; Astle, S.; Gellersen, B.; Thornton, S.; Huhtaniemi, I.; Brosens, J.. "Regulated Expression of membrane progesterone receptors -alpha, -beta and -gamma in pregnant and non-pregnant human uterine and gestational tissues. 12th International Congress of Endocrinology, Lisbon, August 31 - September 4, 2004". Trabalho apresentado em 12th International Congress of Endocrinology, Lisbon, August 31 - September 4, 2004, 2004.
  18. Sousa, M.; Silva, J.; Alves, C.; Fernandes, S.; Carvalho, F.; Ferras, C.; Marques, C.J.; et al. "Treatment of male infertility with maturation arrest. Potential clinical use of cocultures of Sertoli cells with diploid germ cells. XXI International Meeting of the Portuguese Society for Reproductive Medicine, Hotel Riviera, Carcavelos, Lisbon, October 25-26, 2002. 1st Prize Serono-Portugal, best poster presentation.". Trabalho apresentado em XXI International Meeting of the Portuguese Society for Reproductive Medicine, Hotel Riviera, Carcavelos, Lisbon, October 25-26, 2002., 2002.
  19. Pinho, M.J.; Alves, C.; Fernandes, Maria Sofia ; Sousa, M.; Silva, J.; Carvalho, F.; Viana, P.; et al. "Retrospective analysis of 68 Klinefelter infertile patients. First portuguese newborn after ICSI in patients with Klinefelter syndrome. The importance of previous FISH studies on the male germinal epithelium. XXI International Meeting of the Portuguese Society for Reproductive Medicine, Hotel Riviera, Carcavelos, Lisbon, October 25-26, 2002". Trabalho apresentado em XXI International Meeting of the Portuguese Society for Reproductive Medicine, Hotel Riviera, Carcavelos, Lisbon, October 25-26, 2002, 2002.
  20. Cremades, M.; Sousa, M.; Alves, C.; Fernandes, Maria Sofia ; Ferras, L.; Silva, J.; Viana, P.; et al. "Isolation of cell-stage specific populations and molecular characterization of meiosis in maturation arrest. XXIV International Meeting of the Spanish Fertility Society, Palma de Mallorca, Spain, May 23-25, 2002". Trabalho apresentado em XXIV International Meeting of the Spanish Fertility Society, Palma de Mallorca, Spain, May 23-25, 2002, 2002.
  21. Cremades, N.; Alves, C.; Fernandes, Maria Sofia ; Silva, J.; Viana, P.; Oliveira, C.; Teixeira da Silva, J.; et al. "A FISH study of germ cell populations in cases of maturation arrest. XX International Meeting of the Portuguese Society for Reproductive Medicine, Hotel Montebelo, Viseu, October 12-13, 2001. 1st Prize Serono-Portugal, best poster presentation.". Trabalho apresentado em XX International Meeting of the Portuguese Society for Reproductive Medicine, Hotel Montebelo, Viseu, October 12-13, 2001 1st Prize Serono-Portugal, best poster presentation, 2001.
Resumo em conferência
  1. Fernandes, Maria Sofia ; Joana Figueiredo; Diogo Vieira; Soraia Melo; Ana Margarida Moreira; João Miguel Sanches; Raquel Seruca. "Abstract 3348: Unraveling New Strategies for Early Detection of Invasive Cancer Cells: A special Focus on the Nuclear and Cytoskeletal Architecture". Trabalho apresentado em AACR Annual Meeting 2023, Orlando, Florida, Orlando, 2023.
    Publicado
Tese / Dissertação
  1. Fernandes, Maria Sofia. "Expression and Role of Putative Membrane Progestin Receptors in Non-Genomic Hormone Actions in the Female Reproductive Tract (PhD Thesis)". Doutoramento, Imperial College London Faculty of Medicine, 2008.
  2. Fernandes, Maria Sofia. "Characterization of the Novel Membrane Progestin Receptors a and b in Female Reproductive Tissues (MSc Thesis)". Mestrado, Imperial College London Faculty of Medicine, 2003.
  3. Fernandes, Maria Sofia. "Study of the Chromosomic Constitution of the Male Germinal Epithelium Cells Isolated from Patients with Conserved Spermatogenesis and with Azoospermia (BSc Thesis)". Licenciatura, Universidade do Porto Faculdade de Medicina, 2001.
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2022/10/17 Circulating Tumor Cells (CTCs) Capture New Technologies @i3S, what are the new game changer possibilities?
Instituto de Investigação e Inovação em Saúde (i3S) (Porto, Portugal)
2018/06/13 Specific inhibition of p110a subunit of PI3K: putative therapeutic strategy for KRAS mutant colorectal cancer. Seminar at Auditório Mariano Gago, i3S PostDoc Seminar Series, Institute for Research and Innovation in Health (I3S), Porto, Portugal. i3S PostDoc Seminar Series
i3S (Porto, Portugal)
2017/02/10 Specific inhibition of p110a subunit of PI3K: putative therapeutic strategy for KRAS mutant colorectal cancers - Selected Speaker- Presentation at Translating Colorectal Cancer Research Workshop, IPO Porto, Portugal Translating Colorectal Cancer Research Workshop
Portuguese Oncology Institute (IPO- Porto) (Porto, Portugal)
2016/11/03 Specific inhibition of p110a subunit of PI3K: putative therapeutic strategy for KRAS mutant colorectal cancers - Five minute oral speech at I3S Annual Meeting, Póvoa de Varzim, Portugal. I3S Annual Meeting, Póvoa de Varzim, Portugal
(Póvoa de Varzim, Portugal)
2016/04/28 Targeted Inhibition of PI3K p110a as an Alternative Therapeutic Strategy for Colorectal Cancer Patients with KRAS Mutations - Five minute oral speech at Second ASPIC International Meeting, 28-29 April 2016, IPO Porto, Portugal. Second ASPIC International Meeting, 28-29 April 2016, IPO Porto, Portugal.
Portuguese Oncology Institute (IPO- Porto) (Porto, Portugal)
2016/04/28 S100P is a molecular determinant of E-cadherin function in gastric cancer (presented by Carneiro, P). Five minute oral speech at Second ASPIC International Meeting, 28-29 April 2016, IPO Porto, Portugal. Second ASPIC International Meeting
(Porto, Portugal)
2016/04/28 S100P is a molecular determinant of E-cadherin function in gastric cancer (presented by Carneiro P). Five minute oral speech. Second ASPIC International Meeting, 28-29 April 2016, IPO Porto, Portugal. Second ASPIC International Meeting, 28-29 April 2016, IPO Porto, Portugal.
(Porto, Portugal)
2015/03/14 Invited Oral Presentation: "Banco de DNA do HSJ-IPATIMUP: da Concepção à Implementação" V Simpósio Técnico de Anatomia Patológica
Portuguese Oncology Institute (IPO- Porto) (Porto, Portugal)
2014/10/15 Exploring Alternative Therapies in Colorectal Cancer and Identification of Novel Biomarkers Predictive of Therapy Outcome, Ipatimup PostDoc Seminar Series, Ipatimup, Porto, Portugal Ipatimup PostDoc Seminar Series
Ipatimup (Porto, Portugal)
2013/01/29 Exploring Alternative Therapies in Colorectal Cancer and Identification of Novel Biomarkers Predictive of Therapy Outcome, Ipatimup PostDoc Seminar Series, Ipatimup, Porto, Portugal. Ipatimup PostDoc Seminar Series
Ipatimup (Porto, Portugal)
2011/02/15 Exploring Alternative Therapies in Colorectal Cancer and Identification of Novel Biomarkers Predictive of Therapy Outcome, Ipatimup PostDoc Seminar Series, Ipatimup, Porto, Portugal. Ipatimup PostDoc Seminar Series
Ipatimup (Porto, Portugal)
2007/09 Non-Genomic Progesterone Receptors in the Human Female Reproductive Tract (presented by Jan Brosens) - 5th International Meeting on Rapid Responses to Steroid Hormones, Dublin, Ireland, 2-5 September 2007 5th International Meeting on Rapid Responses to Steroid Hormones
(Dublin, Irlanda)
2006/09 Non-Genomic Progesterone Receptors (presented by Jan Brosens)- 12th International Congress on Hormonal Steroids and Cancer, Athens, Greece, 13-16 September 12th International Congress on Hormonal Steroids and Cancer
(Athens, Grécia)
2006/04/05 Cell Membrane Receptors for Progesterone (presented by Jan Brosens)- 8th European Congress of Endocrinology, Glasgow, UK, 1-5 April 2006 8th European Congress of Endocrinology, Glasgow
(Glasgow, Reino Unido)
2005/12/06 Subcellular Localization and Functional Analysis of the Putative Human Membrane Progestin Receptors a, ß and g, Endokrinologikum Hamburg, Hamburg, Germany.
Endokrinologikum Hamburg (Hamburg, Alemanha)
2005/05/18 Expression and Function of the Putative Human Membrane Progestin Receptors a, ß and g - IRDB PhD Seminar Series, Institute of Reproductive and Developmental and Biology (IRDB), Imperial College London, London, UK IRDB PhD seminar Series
Imperial college London, London, UK (London, Reino Unido)
2005/03 Subcellular localization and functional analysis of the putative human membrane progestin receptors hmPR-alpha, -beta and -gamma (presented by T. Krietsch). Rapid Responses to Steroid Hormones, San Diego, California, USA, 28-30 March Rapid Responses to Steroid Hormones, San Diego, California, USA, 28-30 March
(San Diego, Estados Unidos)
2004/04/21 Expression and Function of the Novel Membrane Progestin Receptors in Female Reproductive Tissues, CREDE (Turku)-IRDB (London) Meeting
Imperial college London, London, UK (London, Reino Unido)
2001 Molecular cytogenetic study of the human seminiferous epithelium: the case of maturation arrest (presented by Cremades N). XX International Meeting for the Study of Reproduction, Hotel Montebelo, Viseu, Portugal, October 12-13, 1st Prize, Serono International, best Oral Presentation. XX International Meeting for the Study of Reproduction, Hotel Montebelo, Viseu, Portugal, October 12-13
(Viseu, Portugal)

Orientação

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2021 - 2022/11/21 Unraveling the Cytoskeletal Architecture of Cancer Cells: Development of a Novel Computational Approach
Coorientador
 MSc (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2011 - 2012 The role of KRAS mutations signalling in autophagy control in Colorectal Carcinomas
Coorientador
 Master (Mestrado)
Universidade do Minho, Portugal

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação) 		Instituição / Organização
2018/10/26 - 2018/10/26 Member of the Organizing Committee of the Colorectal Cancer Meeting: “Cancro Colorectal em Portugal: da investigação à prevenção e ao tratamento” (2018/10/26 - 2018/10/26)
Conferência (Membro da Comissão Organizadora)
 Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Participação em evento

Descrição da atividade
Tipo de evento 		Nome do evento
Instituição / Organização
2024/01/25 - 2024/01/27 IX Symposium Liquid Biopsy, 25-27 January 2024, Santiago de Compostela, Spain.
Simpósio
 IX Symposium Liquid Biopsy, 25-27 January 2024, Santiago de Compostela, Spain.
2023/09/22 - 2023/09/22 Lung Cancer Fight Club - 1st Round, 22 September 2023, Champalimaud Foundation, Lisbon, Portugal
Encontro
 Lung Cancer Fight Club - 1st Round, 22 September 2023, Champalimaud Foundation, Lisbon, Portugal
2023/04/14 - 2023/04/19 AACR 2023 Annual Meeting, Orlando, Florida
Encontro
 AACR Annual Meeting 2023, Orlando, Florida
2022/06/30 - 2022/07/01 5th ASPIC International Congress, IPO-Porto, Portugal; 30 June- 1 July 2022.
Congresso
 5th ASPIC International Congress
Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
2022/05/23 - 2022/05/27 Certified User of the CellSearch System (FDA-cleared system for identification, isolation, and enumeration of Circulating Tumor Cells). Training and certification provided by Menarini Silicon Biosystems, Bologna, Italy.
Outro
 Training by Menarini Silicon Biosystems, Bologna, Italy
2022/05/16 - 2022/05/20 Certified User of the DEPArray Plus System. Training and Certification provided by Menarini Silicon Biosystems, Bologna, Italy.
Outro
 Training by Menarini Silicon Biosystems, Bologna, Italy
2022/01 - 2022/01 Workshop: Introduction to information design for life sciences, 2nd edition (8, 9, 14, 21 and 23 February 2022)
Oficina (workshop)
 Workshop: Introduction to information design for life sciences, 2nd edition
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2021/10/14 - 2021/10/15 II ASPIC-ASEICA International Meeting - Current Trends in Precision Medicine in Cancer, 14-15 October 2021, Online event
Encontro
 II ASPIC-ASEICA International Meeting - Current Trends in Precision Medicine in Cancer
European Association For Cancer Research, Reino Unido

Associação Portuguesa de Investigação em Cancro (ASPIC), Portugal

Asociación Española de Investigación sobre el Cáncer (ASEICA), Espanha
2021/10/01 - 2021/10/05 21st International Meeting on Adhesion Biology, 01-05 October 2021, Marvão, Portugal
Encontro
 21st International Meeting on Adhesion Biology
Max Planck Institute of Biochemistry, Alemanha
2021/05/20 - 2021/05/21 27th PORTO CANCER MEETING - Stemness & Metastasis: Advances in Research and Clinical Translation 20-21 May 2021, Online event
Encontro
 27th PORTO CANCER MEETING - Stemness & Metastasis: Advances in Research and Clinical Translation
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
2019/11/28 - 2019/11/29 8th Annual i3S Meeting, 28-29 November 2019, Axis Vermar Conference & Beach Hotel, Póvoa de Varzim, Portugal
Encontro
 8th Annual i3S Meeting
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2019/09/24 - 2019/09/27 Course “Introduction to Digital BioImage Analysis” (Theoretical and Practical), i3S, Porto, Portugal
Outro
 Course “Introduction to Digital BioImage Analysis”
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2018/11/29 - 2018/11/30 7th Annual i3S Meeting, 29-30 November 2018, Axis Vermar Conference & Beach Hotel, Póvoa de Varzim, Portugal;
Encontro
 7th Annual i3S Meeting, 29-30 November 2018
2018/10/26 - 2018/10/26 Colorectal Cancer Meeting: “Cancro Colorectal em Portugal: da investigação à prevenção e ao tratamento”, open to researchers and general public, 26 October 2018, I3S.
Encontro
 Cancro Colorectal em Portugal: da investigação à prevenção e ao tratamento
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2017/11/09 - 2017/11/10 6th Annual i3S Meeting, 9-10 November 2017, Axis Vermar Conference & Beach Hotel, Póvoa de Varzim, Portugal;
Encontro
 6th Annual i3S Meeting
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2017/07/04 - 2017/07/06 Workshop on Advanced Cell Imaging: SP8 DIVE for Multicolor Multi-photon imaging and DMi8S inverted microscope for Advanced Live Cell Imaging” by Leica Team.
Oficina (workshop)
 Workshop on Advanced Cell Imaging: SP8 DIVE for Multicolor Multi-photon imaging and DMi8S inverted microscope for Advanced Live Cell Imaging” by Leica Team.
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2016/11/03 - 2016/11/04 5th Annual i3S Meeting, 3-4 November 2016, Axis Vermar Conference & Beach Hotel, Póvoa de Varzim, Portugal;
Encontro
 5th Annual i3S Meeting
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2015/11/14 - 2015/11/15 Ipatimup Open Day - Dissemination of scientific information to the general public on cancer aetiology, prevention, early detection and available therapies, Ipatimup, Porto, Portugal
Exposição
 Ipatimup Open Day
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
2014/10/30 - 2014/10/31 4th Annual i3S Meeting, 30-31 October 2014, Axis Vermar Conference & Beach Hotel, Póvoa de Varzim, Portugal;
Encontro
 4th Annual i3S Meeting
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2014/05/05 - 2014/05/12 Ipatimup 25 years - Dissemination of scientific information to the general public on colorectal cancer aetiology, prevention, early detection and available therapies, Ipatimup and Câmara Municipal do Porto, Porto, Portugal
Exposição
 Ipatimup 25 years
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal

Câmara Municipal do Porto, Portugal
2012/06/18 - 2012/06/22 4th Course on Optical Microscopy Imaging for Biosciences
Outro
 4th Course on Optical Microscopy Imaging for Biosciences, at IBMC
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2012/06/18 - 2012/06/22 Practical Sessions - 4th Course on Optical Microscopy Imaging for Biosciences
Outro
 4th Course on Optical Microscopy Imaging for Biosciences
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2012/05/10 - 2012/05/11 3rd Annual i3S Meeting, 10-11 May 2012, Axis Vermar Conference & Beach Hotel, Póvoa de Varzim, Portugal;
Encontro
 3rd Annual i3S Meeting
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2011/05/05 - 2011/05/06 2nd i3S Retreat, 5-6 May 2011, Axis Vermar Conference & Beach Hotel, Póvoa de Varzim, Portugal;
Encontro
 2nd i3S Retreat
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2010/05/06 - 2010/05/07 1st I3S Retreat, 6-7 May 2010, Axis Vermar Conference & Beach Hotel, Póvoa de Varzim, Portugal;
Encontro
 1st I3S Retreat
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2009/12/11 - 2009/12/11 Conference on Microbiology and the Biology of Cancer
Conferência
 Conference on Microbiology and the Biology of Cancer
Universidade do Porto Faculdade de Farmácia, Portugal
2009/12/04 - 2009/12/04 Meeting on the New Biological aspects In Breast Cancer Detection
Encontro
 Meeting on the New Biological aspects In Breast Cancer Detection
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
2008/12/15 - 2008/12/19 Academic Visitor at the National DNA Bank, Centre of Cancer Research, University of Salamanca, Spain
Outro
 Academic Visitor at the National DNA Bank, Centre of Cancer Research, University of Salamanca, Spain
Universidad de Salamanca, Espanha
2005/04/01 - 2005/04/30 Academic Visitor at Endokrinologikum Hamburg, Germany (under the supervision of Birgit Gellersen and Tom Krietsch)
Outro
 Academic Visitor at Endokrinologikum Hamburg, Germany (under the supervision of Birgit Gellersen and Tom Krietsch)
endokrinologikum Hamburg, Alemanha
2004/05/19 - 2004/05/19 Course in Statistical Package for the Social Sciences (SPSS), Imperial College London, London, United Kingdom
Outro
 Course in Statistical Package for the Social Sciences (SPSS), Imperial College London, London, United Kingdom
Imperial College London, Reino Unido
2003/03/27 - 2003/03/27 Course in Genetic Modification Safety, Imperial College London, London, United Kingdom;
Outro
 Course in Genetic Modification Safety, Imperial College London, London, United Kingdom;
Imperial College London, Reino Unido
2002/06/30 - 2002/07/03 18th Annual Meeting of the European Society of Human Reproduction and Embryology, 30 June-3 July 2002, Wien Austria.
Encontro
 18th Annual Meeting of the European Society of Human Reproduction and Embryology
2001/01 - 2001/07 Course in Electronic Microscopy Transmission, Laboratory of Cell Biology, Institute of Biomedical Sciences Abel Salazar, University of Porto, Portugal (6 months course)
Outro
 Course in Electronic Microscopy Transmission, Laboratory of Cell Biology, Institute of Biomedical Sciences Abel Salazar, University of Porto, Portugal (6 months course)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2001/05/21 - 2001/05/25 Course in Human Gene Mapping Disease, Institute of Cellular and Molecular Biology of Porto, Portugal;
Outro
 Course in Human Gene Mapping Disease, Institute of Cellular and Molecular Biology of Porto, Portugal;
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2000/10/13 - 2000/10/14 4th Meeting of the Portuguese Society of Human Genetics, 13-14 October 2000, Porto, Portugal
Encontro
 4th Meeting of the Portuguese Society of Human Genetics
2000/09/28 - 2000/09/30 12th National Conference of Biochemistry organized by the Portuguese Society of Biochemistry, 28-30 September 2000, Póvoa de Varzim, Portugal;
Conferência
 12th National Conference of Biochemistry
Sociedade Portuguesa de Bioquímica, Portugal
1998/11/28 - 1998/11/30 11th National Conference of Biochemistry organized by the Portuguese Society of Biochemistry, 28-30 November 1998, Tomar, Portugal;
Conferência
 11th National Conference of Biochemistry
Sociedade Portuguesa de Bioquímica, Portugal

Júri de grau académico

Tema
Tipo de participação 		Nome do candidato (Tipo de grau)
Instituição / Organização
2012/12/12 The role of KRAS mutations signalling in autophagy control in Colorectal Carcinomas
Vogal
 Paula Alexandra Martins Cosme Vieira de Castro (Mestrado)
Universidade do Minho, Portugal

Arbitragem científica em revista

Nome da revista (ISSN) Editora
2019 - 2019 EBioMedicine - The Lancet (Reviewer) (2352-3964) Elsevier
2018 - 2018 British Journal of Cancer (Reviewer) (1532-1827) Springer Science and Business Media LLC
2017 - 2017 PLoS ONE (Reviewer) (1932-6203) Public Library of Science
2012 - 2012 Cellular and Molecular Life Sciences (Reviewer) (1420-9071) Springer-Verlag
2012 - 2012 Archives of Medical Research (Reviewer) (0188-4409) Elsevier

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2010 - Atual Master in Medicine and Molecular Oncology (Oncobiology Module): "Oncogenes and Cancer Therapy in Colorectal Cancer" Master in Medicine and Molecular Oncology (Oncobiology Module) (Mestrado integrado) Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Universidade do Porto Faculdade de Medicina, Portugal
2010 - Atual PhD Program in Medicine and Molecular Oncology; PhD Program in Biomedicine; PhD Program in Pathology and Molecular Genetics (Oncobiology Module): "Oncogenes and Cancer Therapy in Colorectal Cancer" PhD (Curso de doutoramento (conclusão de unidades curriculares)) Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal

Universidade do Porto Faculdade de Medicina, Portugal
2016 - 2018 PhD Program - Graduate Program in Areas of Basic and Applied Biology (GABBA); Oncobiology Module: "Oncogenes and Tumor Suppressor Genes" PhD Program - Graduate Program in Areas of Basic and Applied Biology (GABBA); Oncobiology Module Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2011 - 2012 PhD Program Gulbenkian-Champalimaud (Project Monitor - Taught course) PhD Program Gulbenkian-Champalimaud (Project Monitor - Taught course) Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
2010 - 2010 PhD Program - Graduate Program in Areas of Basic and Applied Biology (GABBA); Oncobiology Module: "Oncogenes and Tumor Suppressor Genes" GABBA PhD Program (Oncobiology Module) (Curso de doutoramento (conclusão de unidades curriculares)) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2005 - 2005 "Progesterone Receptor Biology" lecture to students of the MSc in Human Reproductive Biology, Institute of Reproductive Biology, Imperial College London MSc in Human Reproductive Biology (Master Universitario) Imperial College London Faculty of Medicine, Reino Unido

Membro de associação

Nome da associação Tipo de participação
2016/02/29 - Atual Member of the European Association for Cancer Research (EACR) (EACR22494) Member EACR22494
2016/02/29 - Atual Member of the Associação Portuguesa de Investigação em Cancro (ASPIC) Member

Membro de comissão

Descrição da atividade
Tipo de participação 		Instituição / Organização
2017 - Atual Member of the organizing Commmittee for the establishment of a Colorectal Cancer Consortium in Portugal
Membro
 Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Tutoria

Tópico Nome do aluno
2019 - 2020 Tracing Gastric Cancer using Bioimaging Analysis (PhD Student) Ana Margarida Moreira
2019 - 2020 Development of Bioimaging Tolls for Cell Cycle Analysis (MSc student) Hemaxi Narutamo
2012 - 2016 Colorectal Cancer Biomarkers and Targeted Therapies. Soraia Melo
Distinções

Prémio

2022 Team Member - Grant Liga Portuguesa Contra o Cancro (LPCC) / Ausonia Cancro da Mama 2022
Liga Portuguesa Contra o Cancro, Portugal

Outra distinção

2003 MSc with Distinction at Imperial College London, London, UK
Imperial College London Faculty of Medicine, Reino Unido