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Artemizia Tatiana Santos Évora obtained her Bachelor’s degree in Biology from Universidade de Évora, Escola de Ciências e Tecnologia, and completed her Master`s in Biochemistry and Biomedicine at Universidade de Lisboa, Faculdade de Ciências in January 2024, achieving a combined BSc+MSc average of 16/20. She developed her master’s thesis at the NeuroSignal Lab, coordinated by Professor Doctor Dora Brites at iMed, Universidade de Lisboa, Faculdade de Farmácia, obtaining a final grade of 19/20. Her research focused on the development of a miR-124-3p-loaded exosome strategy and validation of its therapeutic potential in a multi-compartment microfluidic device containing neuron-glia that recapitulates age-AD pathological features as part of a competitively funded research project (PTDC/MED-NEU/2382/2021). Her work resulted in a first-author publication in a Q1 peer-reviewed journal (Évora et al., Frontiers in Pharmacology, 2025). Artemizia has also actively contributed to scientific dissemination through multiple oral and poster presentations. She was selected to give an oral presentation at the 54th Meeting of the Portuguese Society of Pharmacology, presented her research work at the 4th Biochemistry Master’s Meeting at the Universidade de Lisboa, Faculdade de Ciências, Lisboa and co-authored 6 additional oral presentations. She also presented 4 first-author posters at national conferences and contributed as a co-author to 1 poster at prestigious conferences, including the 2nd Symposium on Alzheimer’s Disease; VII/VIII Symposium of the Portuguese Glial Network; 54th Meeting of the Portuguese Society of Pharmacology; and AD/PD24. In November 2024, Artemizia was awarded a research fellowship at the CNR-NANOTEC, Institute of Nanotechnology in Lecce, Italy, within the EU and PNC Italian Health Ministry funded project “Preclinical Development of Gene Therapy for Dystrophic Epidermolysis Bullosa” (PNRR-MR1-2022-12376725). During this fellowship she gained expertise in 3D printing, microfluid devices fabrication, and human induced Pluripotent Stem Cells (hiPSCs). In April 2025, she was competitively granted a researcher fellowship at Universidade Nova de Lisboa, Nova Medical School, to work on how metabolism regulates neural stem cells in normal and tumor brains. Artemizia has developed technical expertise in neuroscience, stem cell research and induced Pluripotent Stem Cell (iPSC) culture, with proficiency in RT-qPCR, imaging, immunocytochemistry, and bioinformatics software including ImageJ, iBright, and GraphPad. Her main research areas of interest include Neuroscience, Neural Stem Cells, Genetics and Oncology, with a particular focus on the impact of metabolism and regulation of neural stem cells on neural stem cells in the context of tumors.
Identificação

Identificação pessoal

Nome completo
Artemizia Tatiana Santos Évora

Nomes de citação

  • Évora, Artemizia
  • Évora, A
  • A,Évora

Identificadores de autor

Ciência ID
A913-5D88-0CB7
ORCID iD
0000-0001-6454-2341

Endereços de correio eletrónico

  • artemiziasantos52@gmail.com (Profissional)

Websites

  • www.linkedin.com/in/artemízia-évora-940567294 (Profissional)

Domínios de atuação

  • Ciências Médicas e da Saúde - Medicina Básica - Neurociências
  • Ciências Médicas e da Saúde - Biotecnologia Médica - Tecnologias que envolvem a Manipulação de Células,Tecidos,Órgãos ou todo o Organismo
  • Ciências Naturais - Ciências Biológicas - Biologia Celular

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Espanhol; Castelhano Utilizador elementar (A2) Utilizador elementar (A2) Utilizador elementar (A2) Utilizador independente (B1) Utilizador elementar (A2)
Formação
Grau Classificação
2021/10/06 - 2024/01/11
Concluído
Bioquimica e Biomedicina (Mestrado)
Universidade de Lisboa Faculdade de Ciências, Portugal
"Strategies of miR-124-3p Enrichment in Neuronal Exosomes and Reparative Effects in Human Tricultures Modeling Aging, Neurodegeneration, and Inflammation in Alzheimer’s Disease (19/20)." (TESE/DISSERTAÇÃO)
17
2018 - 2021
Concluído
Biologia (Licenciatura)
Universidade de Évora, Portugal
"Évora, a cidade que educa -Cogumelos no Alto de S. Bento (16/20)" (TESE/DISSERTAÇÃO)
14
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento
Empregador
2025/04 - Atual Investigador (Investigação) Universidade Nova de Lisboa Medical School, Portugal
Proliferation and Fate Regulation of Stem Cells Group , Portugal
2024/11 - 2055/02 Investigador (Investigação) Consiglio Nazionale delle Ricerche, Itália
Instituto de Nanotecnologia, CNR-NANOTEC, Itália

Outros

Categoria Profissional
Instituição de acolhimento
Empregador
2022/09 - 2024/01 Master Student Universidade de Lisboa Faculdade de Farmácia, Portugal
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
(...)
2021 - 2021 Bachelor Student Universidade de Évora, Portugal
Macromycology Laboratory, Portugal
Projetos

Bolsa

Designação Financiadores
2025/04 - Atual Laboratórios Associados - LA/P/0087/2020-LS4F
LA/P/0087/2020-LS4F
Bolseiro de Investigação
Universidade Nova de Lisboa Medical School, Portugal
Fundação para a Ciência e a Tecnologia
2024 - 2025 Pre-clinical development of gene therapy for dystrophic epidermolysis bullosa
PNRR-MR1-2022-12376725
Bolseiro de Investigação
EU funded within the PNC Italian Health Ministry

Projeto

Designação Financiadores
2022/01/01 - 2024/12/31 Analyzing NeuroIMmune dysregulation in Alzheimer´s disease toward a Therapy with miRNA-loaded Exosomes
PTDC/MED-NEU/2382/2021
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal

Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal

Universidade de Lisboa Faculdade de Farmácia, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
Produções

Publicações

Artigo em conferência
  1. Garcia, Gonçalo; Évora, Artemizia; Corraliza-Gomez, Miriam; Ianni, Marta; Costa-Pinto, Sara; Frank Stein; Ana Rubi; et al. "EXOSOMAL MICRORNA-124-3P DELIVERY AS A THERAPEUTIC STRATEGY IN ALZHEIMER'S DISEASE". Trabalho apresentado em Annual Meeting of the European Tissue Repair Society (ETRS) & Portuguese Society of Stem Cell Therapies (SPCE-TC) 2023, 2023.
    Publicado • https://doi.org/10.1111/wrr.13132
Artigo em revista
  1. Artemizia Évora; Gonçalo Garcia 2,3Garcia, Gonçalo; Ana Rubi; Eleonora De Vitis; Ana Teresa Matos ; Ana Rita Vaz ; Francesca Gervaso; et al. Autor correspondente: Dora Brites. "Exosomes enriched in miR-124-3p show therapeutic potential in a new microfluidic triculture model that recapitulates neuron-glia crosstalk in Alzheimer's disease". Frontiers in Pharmacology 16 (2025): https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2025.1474012/abstract.
    Acesso aberto • Publicado
Poster em conferência
  1. Garcia G, Évora A, Corraliza-Gomez M, Ianni M, Rubi A, Matos AT, Barbosa R, Vaz AR, Polini A, Brites D. "Tailored exosomal miRNA-124-3p delivery: a targeted therapeutic approach for Alzheimer's disease". Trabalho apresentado em International Conference on Alzheimer’s and Parkinson’s Diseases and related neurological disorders (AD/PD), 2024.
  2. A,Évora; G. Garcia; A. Rubi; AT. Matos; AR. Vaz; F. Gervaso; A. Polini; D. Brites. "Exploring the Potential of mir-124-3p Enriched Exosomes in a Human Neuron- Astrocyte-Microglia Microfluidic system as model of Alzheimer's Disease". Trabalho apresentado em VIII Symposium of the Portuguese Glial Network, 2024.
  3. Évora A, Rubi A, De Vitis E, Podobnik E, Matos AT, Barbosa R, Vaz AR, Gervaso F, Polini A, Garcia G, Brites D. "Engineering exosomal miR-124-3p for enhanced delivery and therapeutic translation using human neuron-microglia-astrocyte triculture models of AD". Trabalho apresentado em iMed.ULisboa Meeting 2023, 2023.
  4. Évora A, Rubi A1, De Vitis E2, Podobnik E1, Matos AT1, Vaz AR1,3, Gervaso F2, Polini A2, Garcia G1, Brites D. "Development of a human triculture model of neuron-microglia-astrocyte crosstalk to investigate AD and test engineered miR-124-3p exosomes". Trabalho apresentado em VII Symposium of the Portuguese Glial Network, 2023.
  5. Évora A, G. Garcia, A. Rubi, E. Podobnik, A.T. Matos, R. Barbosa, A.R. Vaz, D. Brites D. "Novel Alzheimer's disease therapeutic strategies based on engineering small extracellular vesicles with miR-124-3p". Trabalho apresentado em 2nd Symposium on Alzheimer’s Disease: An Update on Pathology and Therapeutics, 2023.
Tese / Dissertação
  1. "Strategies of miR-124-3p Enrichment in Neuronal Exosomes and Reparative Effects in Human Tricultures Modeling Aging, Neurodegeneration, and Inflammation in Alzheimer`s Disease". Mestrado, Universidade de Lisboa Faculdade de Ciências, 2024.
  2. "Évora, a cidade que educa - Cogumelos no Alto de S. Bento". Licenciatura, Universidade de Évora Escola de Ciências e Tecnologia, 2021.

Artística / Interpretação

Gravação vídeo
  1. Évora, Artemizia ( Oral Communication); Mafalda Carapuço (Produtor); Mafalda Carapuço (Realizador). 2016. The Nazaré Wave-a trigger for learning. Faculdade de Ciências da Universidade de Lisboa.
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2024/04/21 Évora A, G. Garcia, A. Rubi, AT. Matos, AR. Vaz, F. Gervaso, A. Polini2, D. Brites. "Unveiling the Therapeutic Potential of miR-124-3p-Engineered Exosomes with a Neuron-Glia Microfluidic Human Model of Alzheimer's Disease”. 54th Meeting of the Portuguese Society of Pharmacology
Nova Medical School (Lisboa, Portugal)
2023/11/10 Garcia G, Évora A, Corraliza-Gomez M, Ianni M, Pinto S, Stein F, Rubi A, Matos AT, Barbosa R, Fernandes A, Vaz AR, Polini A, Edenhofer F, Malm T, Koistinaho J, Brites D. "Exosomal microRNA-124-3p delivery as a therapeutic strategy in Alzheimer’s disease". Annual Meeting of the European Tissue Repair Society (ETRS) & SPCE-TC
Universidade de Coimbra (Coimbra, Portugal)
2023/06/30 Garcia G, Évora A, Rubi A, Podobnik E, Corraliza-Gomez M, Ianni M, Matos AT, Barbosa R, Vaz AR, Polini A, Brites D. "Investigating miRNA (dys)regulation in Alzheimer's disease cell models: Insights into neuroimmune signaling". Young Investigator Seminar Series
Research Institute for Medicines (iMed.ULisboa) (Lisboa, Portugal)
2023/06/22 Garcia G, Évora A, Rubi A, Podobnik E, Corraliza-Gomez M, Ianni M, Matos AT, Barbosa R, Vaz AR, Polini A, Brites D."miR-124-3p-loading in neuronal exosomes as a delivery therapeutic system in Alzheimer's disease". 2nd Meeting of the Portuguese Network on Extracellular Vesicles
Nova Medical School (Lisboa, Portugal)
2023/06/16 Garcia G, Évora A, Rubi A, Podobnik E, Corraliza-Gomez M, Matos AT, Barbosa R, Vaz AR, Polini A and Brites D. "Promise of miR-124-3p-loaded neuronal exosomes for clinical application in Alzheimer’s disease patient subtypes". Workshop on novel diagnostic tools for Alzheimer`s disease
University of Aveiro (Aveiro, Portugal)
2023/04/21 Garcia G, Évora A, Rubi A, Podobnik E, Corraliza-Gomez M, Ianni M, Matos AT, Barbosa R, Vaz AR, Polini A and Brites D. "Studying neuroimmune-associated miRNA (dys)regulation using Alzheimer´s disease cell models". Casual Friday Seminars
Nova Medical School (Lisboa, Portugal)
2022/11 Evora, A; Garcia,G; Brites,D. "Novel therapeutic strategies based on microRNA modulation in diseased cells or direct transfection into extracellular vesicles from neural precursor cells" . 4th Biochemistry Master’s Meeting
Universidade de Lisboa, Faculdade de Ciências (Lisboa, Portugal)

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação)
Instituição / Organização
2021 - 2021 Organizing/staff member of the national meeting of biology students (ENEB) (2021 - 2021)
Encontro (Outra)
Universidade de Coimbra, Portugal

Participação em evento

Descrição da atividade
Tipo de evento
Nome do evento
Instituição / Organização
2025 - 2025 Scintilla Research Project: Study of a familial ALS cluster characterized By the p6376D mutatio
Oficina (workshop)
Scintilla Research Project: Study of a familial ALS cluster characterized By the p6376D mutation in the TARDBP gene
Instituto de Nanotecnologia, CNR-NANOTEC, Itália
2023 - 2023 Webinar series on microglial research
Oficina (workshop)
Microglial states and nomenclature
2023 - 2023 PhD Advanced Course in Neuroscience
Outro
PhD Advanced Course in Neuroscience
2023 - 2023 Workshop on novel diagnostic tools for Alzheimer’s disease
Oficina (workshop)
Workshop on novel diagnostic tools for Alzheimer’s disease
2021 - 2021 Encontro de Estudantes de Bioquímica
Encontro
3th Biochemistry Masters Meeting
Universidade de Lisboa Faculdade de Ciências, Portugal
2021 - 2021 Space microbiology and Astrobiology
Oficina (workshop)
Space microbiology and Astrobiology
2021 - 2021 Computational Pipeline and Characterization of a Protein Interaction
Oficina (workshop)
Computational Pipeline and Characterization of a Protein Interaction
2016 - 2016 Congress on Science Communication-SciCom Portugal
Congresso
Pavilhão do Conhecimento
Pavilhão do Conhecimento-Centro Ciência Viva, Portugal

Membro de associação

Nome da associação Tipo de participação
2019 - 2021 Biology Student`s Council of Évora (C.E.B.E) Vice-president

Tutoria

Tópico Nome do aluno
2023 - 2023 Explicações_Matemática e Biologia e Geologia Mariana Silva