???global.info.a_carregar???
Elisabete Fernandes is an assay development scientist specializing in biosensors. She is a staff researcher in the Nanodevices Group at the International Iberian Nanotechnology Laboratory (INL). Her responsibilities include developing assay formats, surface functionalization, and applying biosensors for medical biomarkers detection. She is also actively involved in the development of the research strategy of the health cluster at INL (as deputy coordinator), and also responsible for the Clinical laboratory at INL, overseeing its implementation (BSL2). Elisabete received her Ph.D. degree in Chemical and Biological Engineering from the University of Minho, Portugal, in 2013. Her doctoral research focused on developing a biosensor using bacteriophages as biorecognition elements, with part of the work conducted at the University of Auburn, USA, and the University of Leuven, Belgium. During her Ph.D., she received a national grant (FCT), and then a Marie Curie Fellowship for her participation in an EU-funded project related to cancer diagnosis. Elisabete has 16 peer-reviewed papers in scientific journals related to biosensors, 1 book chapter in an international scientific book, presented her research through 28 oral communications and 18 posters at various international scientific seminars, workshops, and conferences. Elisabete is currently co-supervising 1 Ph.D. student and 1 Master's student. Previously, she has supervised 1 Postdoc and co-supervised a Ph.D. student (successfully defended in 2022) in the biosensor field applied to stroke, along with 4 Master's. Elisabete has served as project coordinator of Fully Integrated Magnetoresistive Biochip Platform for Stroke Patient Stratification (FIM4Stroke), funded through a national program (FCT, 250k). She has actively participated in several national (5) and international (6) projects. Since 2014, Elisabete has dedicated her primary attention to advancing the development of a Point-of-Care (PoC) technology, specifically focusing on the utilization of Magnetoresistive platforms and the creation of innovative detection strategies for stroke. Beyond her scientific pursuits, Elisabete is a multidisciplinary researcher actively involved in pedagogical projects at national and international levels. Her work has been published in science communication and pedagogical practice conferences. She is also a passionate advocate for knowledge humanization and accessibility. Her commitment to these ideals is evident in her affiliations and engagements. She is proudly associated with National Geographic as a certified educator, actively contributing to the promotion of scientific literacy. Furthermore, Elisabete holds the role of co-founder and leader of Mission NERD, a volunteer project that aims to foster scientific literacy and break stereotypes at INL. In addition to her educational endeavors, Elisabete's dedication to compassion and altruism is exemplified through her certification as an educator and ambassador of applied compassion from Stanford University's Center for Compassion and Altruism Research and Education (CCARE). Through this program, she actively promotes and embodies the principles of compassion in her work and interactions, further enriching her contributions to society.
Identificação

Identificação pessoal

Nome completo
Elisabete Fernandes

Nomes de citação

  • Fernandes, Elisabete

Identificadores de autor

Ciência ID
8B11-15E7-4F5D
ORCID iD
0000-0003-4558-7047
Researcher Id
B-8509-2011

Endereços de correio eletrónico

  • elisabete.fernandes@inl.int (Profissional)

Moradas

  • International Iberian Nanotechnology Laboratory - INL. Avenida Mestre José Veiga s/n, 4715-330, Braga, Braga, Portugal (Profissional)

Websites

Domínios de atuação

  • Ciências da Engenharia e Tecnologias - Nanotecnologia
  • Ciências Sociais - Ciências da Educação

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador independente (B1) Utilizador proficiente (C1)
Espanhol; Castelhano Utilizador independente (B1) Utilizador proficiente (C1) Utilizador independente (B1) Utilizador independente (B1)
Formação
Grau Classificação
2021 - 2022
Concluído
Educator and Ambassador of Applied Compassion, (Outros)
Stanford University, Estados Unidos
2020
Concluído
Certified National Geographic Educator (Outros)
National Geographic Society, Estados Unidos
2013
Concluído
PhD in Chemical and Biological Engineering (Doutoramento)
Universidade do Minho Escola de Engenharia, Portugal
"Development of a phage-based biosensor to detect Salmonella in food stuff." (TESE/DISSERTAÇÃO)
Doctor
2007
Concluído
Biological Engineering (Mestrado integrado)
Universidade do Minho Escola de Engenharia, Portugal
"Bactiophages for Salmonella control: Comparison of different methods of preservation" (TESE/DISSERTAÇÃO)
15
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento
Empregador
2016/12/09 - Atual Investigador Contratado (Investigação) International Iberian Nanotechnology Laboratory, Portugal
2014/06/01 - 2016/12/08 Investigador (Investigação) International Iberian Nanotechnology Laboratory, Portugal
2013/06/01 - 2014/06/30 Investigador Contratado (Investigação) Xeptagen SpA, Itália
École Polytechnique Fédérale de Lausanne, Suiça

Outros

Categoria Profissional
Instituição de acolhimento
Empregador
2020/12/08 - Atual Certified Educator of the National Geographic n/a, Estados Unidos
Projetos

Bolsa

Designação Financiadores
2012/01/01 - 2014/06/01 PROSENSE (Parallel Sensing of Prostate Cancer Biomarkers)
PROSENSE
Bolseiro de Pós-Doutoramento
Concluído

Projeto

Designação Financiadores
2018/10/04 - Atual FIM4Stroke - A Fully Integrated Magnetoresistive Biochip Platform for Stroke Patient Stratification .
PTDC/MEC-URG/29561/2017
Investigador responsável
Fundação para a Ciência e a Tecnologia
Em curso
2017/09/01 - Atual Occult Hepatitis C in Different Clinical Settings: Detection, Characterization and Diagnostic Tools
PTDC/SAU-SER/30788/2017
Investigador
Fundação para a Ciência e a Tecnologia
2017/07/01 - Atual NanoEaters – Early Detection of Peritoneal Fibrosis
0181_NANOEATERS_1_E
Investigador
2016/07/01 - Atual NanoEaters – Biomarkers for early diagnosis of colorectal cancer
0181_NANOEATERS_1_E
Investigador
Em curso
2018/10/01 - 2021/09/30 Infeção Oculta pelo Vírus da Hepatite C em diferentes abordagens clínicas: Deteção, Caracterização e Ferramentas de Diagnóstico
PTDC/SAU-SER/30788/2017
Centro Hospitalar e Universitário de Coimbra EPE, Portugal

International Iberian Nanotechnology Laboratory, Portugal

INESC Microsistemas e Nanotecnologias, Portugal

Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2015/01/01 - 2016 InveNNta 2 - Innovation in Nanomedicine: Design of Nanostructures for the Treatment and Diagnosis of Cancer and Stroke
InveNNta 2
Investigador
Concluído
2013/09/01 - 2015 InveNNta 1 - Innovation in Nanomedicine: Design of Nanostructures for the Treatment and Diagnosis of Cancer and Stroke
InveNNta 1
Investigador
Concluído
2007/09/01 - 2008 European Project Phagevet-P (Veterinary phage therapies as alternatives to antibiotics in poultry production, STREP Project no. 2005-7224)
STREP Project no. 2005-7224
Bolseiro de Iniciação Científica
Concluído

Outro

Designação Financiadores
2017/09/01 - 2019 Hackaton 2017 - On-chip selection of exosomal vectors for neurodegenerative diseases treatment
INL&UMinho
Investigador
Concluído
Produções

Publicações

Artigo em revista
  1. Andrea Cruz; Elisabete Fernandes; Raquel O. Rodrigues; Susana O. Catarino; Diana Pinho. "Editorial: Disease-on-a-chip: from point-of-care to personalized medicine". Frontiers in Pharmacology (2023): http://dx.doi.org/10.3389/fphar.2023.1344379.
    10.3389/fphar.2023.1344379
  2. Briliant Adhi Prabowo; Carole Sousa; Susana Cardoso; Paulo Freitas; Elisabete Fernandes. "Labeling on a Chip of Cellular Fibronectin and Matrix Metallopeptidase-9 in Human Serum". Micromachines (2022): https://doi.org/10.3390/mi13101722.
    10.3390/mi13101722
  3. D. C. Albuquerque; Verónica C. Martins; Elisabete Fernandes; Líbia Zé-Zé; Maria João Alves; Susana Cardoso. "Combined detection of molecular and serological signatures of viral infections: The dual assay concept". Biosensors and Bioelectronics (2022): http://dx.doi.org/10.1016/j.bios.2022.114302.
    10.1016/j.bios.2022.114302
  4. Briliant Adhi Prabowo; Elisabete Fernandes; Paulo Freitas. "A pump-free microfluidic device for fast magnetic labeling of ischemic stroke biomarkers". Analytical and Bioanalytical Chemistry 414 8 (2022): 2571-2583. https://doi.org/10.1007/s00216-022-03915-w.
    10.1007/s00216-022-03915-w
  5. "The Challenges of Developing Biosensors for Clinical Assessment: A Review". Chemosensors 2021 (2021):
    https://doi.org/10.3390/chemosensors9110299
  6. Cabral, Patrícia D.; Domingues, Telma; Machado, George; Chicharo, Alexandre; Cerqueira, Fátima; Fernandes, Elisabete; Athayde, Emília; Alpuim, Pedro; Borme, Jérôme. "Clean-Room Lithographical Processes for the Fabrication of Graphene Biosensors". Materials 13 24 (2020): 5728. http://dx.doi.org/10.3390/ma13245728.
    10.3390/ma13245728
  7. Fernandes, Elisabete; Sobrino, Tomás; Martins, Verónica C.; Lopez-loureiro, Ignacio; Campos, Francisco; Germano, José; Rodríguez-Pérez, Manuel; et al. "Point-of-care quantification of serum cellular fibronectin levels for stratification of ischemic stroke patients". Nanomedicine: Nanotechnology, Biology and Medicine 30 (2020): 102287. http://dx.doi.org/10.1016/j.nano.2020.102287.
    10.1016/j.nano.2020.102287
  8. Fernandes, Elisabete. "Functionalization of single-layer graphene for immunoassays". Applied Surface Science (2019): http://dx.doi.org/10.1016/j.apsusc.2019.03.004.
    10.1016/j.apsusc.2019.03.004
  9. Fernandes, Elisabete. "Detection of BCG bacteria using a magnetoresistive biosensor: A step towards a fully electronic platform for tuberculosis point-of-care detection". Biosensors and Bioelectronics (2018): http://dx.doi.org/10.1016/j.bios.2017.09.004.
    10.1016/j.bios.2017.09.004
  10. Fernandes, Elisabete. "Adapting Bobbert-Vlieger model to spectroscopic ellipsometry of gold nanoparticles with bio-organic shells". Biomedical Optics Express (2017): http://dx.doi.org/10.1364/boe.8.003538.
    10.1364/boe.8.003538
  11. Fernandes, Elisabete. "Rapid and specific detection of cell-derived microvesicles using a magnetoresistive biochip". Analyst (2017):
    10.1039/c6an02651f
  12. Dias, T.M.; Fernandes, E.; Cardoso, S.; Monteiro, G.; Freitas, P.P.. "One-step trapping of droplets and surface functionalization of sensors using gold-patterned structures for multiplexing in biochips". RSC Advances 7 68 (2017): 43273-43282. http://www.scopus.com/inward/record.url?eid=2-s2.0-85029126517&partnerID=MN8TOARS.
    10.1039/c7ra06085h
  13. Freitas, Paulo P.; Martins, Veronica C.; Cardoso, Felipe A.; Fernandes, Elisabete; Sobrino, Tomas; Castillo, Jose; Chicharo, Alexandre; et al. "Spintronic Biochips". Nanomagnetism: Applications and Perspectives (2017): https://doi.org/10.1002/9783527698509.ch9.
    doi:10.1002/9783527698509.ch910.1002/9783527698509.ch9
  14. Fernandes, Elisabete. "A bacteriophage detection tool for viability assessment of Salmonella cells". Biosensors and Bioelectronics (2014): http://dx.doi.org/10.1016/j.bios.2013.08.053.
    10.1016/j.bios.2013.08.053
  15. Fernandes, Elisabete. "Selection and Characterization of a Multivalent Salmonella Phage and Its Production in a Nonpathogenic Escherichia coli Strain". Applied and Environmental Microbiology (2010): http://dx.doi.org/10.1128/aem.00922-10.
    10.1128/aem.00922-10
  16. Fernandes, Elisabete. "Method for bacteriophage isolation against targetCampylobacterstrains". Letters in Applied Microbiology (2010): http://dx.doi.org/10.1111/j.1472-765x.2009.02774.x.
    10.1111/j.1472-765x.2009.02774.x
Poster em conferência
  1. Cabral, Patrícia; Rodrigues, Teresa; Borme, Jérôme; Fernandes, Elisabete; Alpuim, Pedro. "Field-Effect Transistors as biosensors: building up for the end application". Trabalho apresentado em Jornadas CF-UP-UP, 2019.
  2. Fernandes, Elisabete; Freitas, Paulo P.; Cabral, Patrícia; Rodrigues, Teresa; Alpuim, Pedro. "Comparison of magnetoresistive and graphene based platforms for the detection of clinical biomarkers". Trabalho apresentado em INL Annual Research Symposium 2019, 2019.
  3. Alpuim, Pedro; Machado Jr., George; Cabral, Patrícia; Fernandes, Elisabete; Campos, Rui; Borme, Jérôme. "Graphene-based devices for bio-sensing platforms". Trabalho apresentado em Nanolito 2017, 2017.
  4. Cabral, Patrícia D.; Fernandes, Elisabete; Cerqueira, M. Fátima; Machado Jr., George; Borme, Jérôme; Alpuim, Pedro. "Graphene Functionalization for Biosensing". Trabalho apresentado em 1st iBEM – international Biomedical Engineering Meeting,, 2016.
Atividades

Orientação

Título / Tema
Papel desempenhado
Curso (Tipo)
Instituição / Organização
2023/12/01 - 2025/04/07 Shelf-life optimization of antibody-coated sensor surfaces for PoC applications
Orientador
Master in Biomedical Engineering (Mestrado)
Universidade do Minho, Portugal
2018/01/01 - 2025/01/09 Self-sufficient Point-of-care Platform for Diagnosis of Tropical Diseases
Coorientador
Universidade Nova de Lisboa, Portugal
2017/01/01 - 2022/01/05 Immuno-field-effect transistor platforms based on 2D materials for early detection of biomarkers of ischemic stroke
Coorientador
Universidade do Minho, Portugal
2017/01/01 - 2022/01/04 MicroPathID –Rapid in-field microfluidic system for diagnostics of pathogens
Coorientador
Universidade Nova de Lisboa, Portugal
2016 - 2017 Characterization of cell-derived microparticles by nanotechnological methods,
Coorientador
Danmarks Tekniske Universitet, Dinamarca

Júri de grau académico

Tema
Tipo de participação
Nome do candidato (Tipo de grau)
Instituição / Organização
2024/03/21 LOBOWARNING – Mitigation of Globodera spp. outbreaks in Portugal through an innovative early nano-detection system and biocontrol Maria João Santiago Militão Camacho (Doutoramento)
2022/05/18 Microfluidic biosensor for antibody therapy management Inês Raquel da Silva Iria (Doutoramento)
2022/01/19 Graphene field-effect transistors functionalization for neurotransmitter18 / 27 biosensing
Arguente principal
Mafalda Abrantes (Mestrado)
2021/01/19 Development of a microfluidic sample preparation system for bacteria magnetic labelling and capture in clinical samples
Arguente principal
Davide Carta (Mestrado)
2017/12/07 Prototyping a Spintronics Labon-Chip system for cancer liquid biopsy analysis
Arguente principal
Tomás Miguel de Freitas Dias (Doutoramento)
2016/10/28 Studying DNA compaction by the Condensin complex using magnetic tweezers
Arguente principal
Ana Carolina Faustino Mota (Mestrado)
2016/06/17 Optimization of a Lab-On-Chip Device to Study the Biocementation of Soils
Arguente principal
João Pedro Pereira Valentim (Mestrado)

Arbitragem científica em conferência

Nome da conferência Local da conferência
2025 - Atual I Simpósio Nacional de Mulheres na Nanociência Instituto de Ciências Exatas - ICE - UFJF - Juiz de Fora - Minas Gerais - Brasil
2024 - 2025 2nd and 3rd Portuguese Network on Extracellular Vesicles (PNEV)

Membro de associação

Nome da associação Tipo de participação
2014/01/01 - Atual Marie Curie Alumni Association (MCFA) Member Member

Outro júri / avaliação

Descrição da atividade Instituição / Organização
2018/10/04 - Atual Thesis Plan, Doctoral Program in Biomedical Engineering, Development of a phage-based lab-on-chip for the multiplex detection of bloodstream pathogens Universidade do Minho Centro de Engenharia Biológica, Portugal