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Paula C Castilho graduated in Chemistry in 1985 by the Faculty of Sciences of University of Lisbon and, in 1991, finished her PhD in Physical Organic Chemistry at the Chemistry Department of the University of Durham, UK. Worked as resaercher in the National Laboratory for Engineering and Industrial Technology before launching a Chemistry Department at the newly founded Madeira University (UMa). She was Vice-Rector of UMa, in charge of finances and logistics of the building and furbishing of the new Campus. PCC is a founding member of Centro de Química da Madeira, responsible for the Laboratory of Organic Chemistry and Natural Products. Currently, she is also a member of the CQM Executive Board. PCC became an associate professor in Organic Chemistry in 2002 and has held that position ever since. I was head of the Chemistry Department from 2004 to 2019, during which the 3rd cycle (Ph.D.) in Chemistry was created, being its director since the beginning. The scientific activity was readjusted from Physical Organic Chemistry to the area of Natural Products, and PPC has been the proponent and participant of several projects financed by FCT and other European Community sponsorships and others with the private sector. PCC successfully supervised 16 Master students, 4 PhD students (6 currently enrolled), and several postdocs. She is a member of Sociedade Portuguesa de Química (SPQ), Sociedade Portuguesa de Fitoquímica e Fitoterapia (SPFito), and Phytochemical Society of Europe (PSE), where she is the representative of Iberia during the last 5 years.
Identificação

Identificação pessoal

Nome completo
Paula C Castilho

Nomes de citação

  • Castilho, Paula C

Identificadores de autor

Ciência ID
6D15-8C69-A2E0
ORCID iD
0000-0002-8303-4286
Google Scholar ID
https://scholar.google.pt/citations?user=yqofvq8AAAAJ&hl=pt-PT
Researcher Id
A-4412-2013

Endereços de correio eletrónico

  • pcastilho@staff.uma.pt (Profissional)
  • castilho@uma.pt (Profissional)

Telefones

Telefone
  • 291705102 (Profissional)

Moradas

  • Centro de Química da Madeira - Faculdade de Ciencias Exactas e da Engenharia - Química, Universidade da Madeira. Campus Universitário da Penteada, 9020-105, Funchal, Funchal, Portugal (Profissional)

Domínios de atuação

  • Ciências Agrárias - Biotecnologia Agrária e Alimentar
  • Ciências Exatas - Química - Química Orgânica
  • Ciências Naturais - Ciências Biológicas - Bioquímica
  • Ciências Exatas - Química - Química Orgânica

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Francês Utilizador elementar (A1) Utilizador independente (B1) Utilizador elementar (A1) Utilizador elementar (A1)
Espanhol; Castelhano Utilizador independente (B2) Utilizador proficiente (C1) Utilizador elementar (A2) Utilizador proficiente (C1)
Formação
Grau Classificação
1987/10/01 - 1991/01/28
Concluído
PhD in Chemistry (Doctor of Philosophy)
Especialização em Physical Organic Chemistry
Durham University, Reino Unido
"Some Spectroscopic, Kinetic and equilibria Studies do Cyano- and Nitro-substituted Anisoles and Phenols and their Reactions with Nucleophiles" (TESE/DISSERTAÇÃO)
n.a.
1977/10/01 - 1985/01/30
Concluído
Química (Licenciatura)
Especialização em Química Física e Inorgânica
Universidade de Lisboa Faculdade de Ciências, Portugal
14
Percurso profissional

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento
Empregador
2002/02/01 - Atual Professor Associado (Docente Universitário) Universidade da Madeira Centro de Química da Madeira, Portugal
1992 - 2002 Professor Auxiliar (Docente Universitário) Universidade da Madeira, Portugal

Cargos e Funções

Categoria Profissional
Instituição de acolhimento
Empregador
2009/10/01 - Atual Directora de Curso 1º ciclo Bioquímica Universidade da Madeira, Portugal
Universidade da Madeira, Portugal
2009/09/01 - Atual Directora de curso 3º Ciclo Química (doutoramento) Universidade da Madeira, Portugal
Universidade da Madeira, Portugal
2013 - 2024 Conselho pedagógico Universidade da Madeira, Portugal
2016 - 2019 Coordenação ou direção de centro de investigação, departamento ou equivalente Universidade da Madeira, Portugal
2017 - 2018 Conselho científico/técnico-científico ou orgão correspondente Universidade da Madeira, Portugal
2013 - 2016 Conselho científico/técnico-científico ou orgão correspondente Universidade da Madeira, Portugal

Outros

Categoria Profissional
Instituição de acolhimento
Empregador
2004 - 2024 Leader of Natural Products Group Universidade da Madeira Centro de Química da Madeira, Portugal
2004 - 2019 Head of Chemistry Department Universidade da Madeira, Portugal
2009/02/04 - 2013/10/15 Elected Member of University General Board (Conselho Geral) Universidade da Madeira, Portugal
1996 - 2013 Member of Senate Universidade da Madeira, Portugal
2000 - 2004 Director of Research Group on Food and Environmental Chemistry Universidade da Madeira, Portugal
1996 - 2000 Vice Rector Universidade da Madeira, Portugal
1994 - 1996 Vice President of Scientific Board Universidade da Madeira, Portugal
1992 - 1996 Head of Chemistry Department Universidade da Madeira, Portugal
Projetos

Projeto

Designação Financiadores
2023/03/01 - 2027/02/28 Red Temática IBEROCIRCULAR Innovación y sostenibilidad para la Cadena de Valor de Vegetales
Co-Investigador Responsável (Co-IR)
Universidade da Madeira Centro de Química da Madeira, Portugal
Ciencia y Tecnología para el Desarrollo
Em curso
2024/06/01 - 2026/01/01 PASPACK 4.0 Producing Alternative Sustainable food bio-based PACKaging from Mediterranean agri-food by-products and waste
PRIMA - PasPack 4.0
Investigador
Universidade da Madeira Centro de Química da Madeira, Portugal
European Union
Em curso
2019/06/01 - 2023/12/31 MACBIOPEST - BIOPESTICIDAS BOTÁNICOS DE LA MACARONESIA: INVESTIGACIÓN Y SABER POPULAR
: MAC2/1.1a/289
Investigador responsável
Universidade da Madeira Centro de Química da Madeira, Portugal
Interreg Europe
Concluído
2018/01/01 - 2023/06/30 PREMIUM - Preservation of microorganisms by understanding the protective mechanisms ofoligosac
H2020-MSCA-RISE-2017, 777657
Investigador responsável
Universidade da Madeira Centro de Química da Madeira, Portugal
European Commission Marie Sklodowska-Curie Actions
Concluído
2017/02/01 - 2019/01/31 MARINEBLUEREFINE
M1420-01-0247-FEDER-000006
Investigador responsável
Universidade da Madeira Centro de Química da Madeira, Portugal
Concluído
2012/03 - 2015/03 Ocean Treasures - Ocean sediments from Madeira Archipelago: a new source of innovative and bioactive compounds. Fundação para a Ciência e a Tecnologia, I.P.
2012/02 - 2015/01 CLAYCATS4 - Clay catalysts for biomass conversion Fundação para a Ciência e a Tecnologia, I.P.
2012/04 - 2014/03 SSAD - Solid (super) acids catalyzed biomass desconstruction Fundação para a Ciência e a Tecnologia, I.P.
2011/01/01 - 2013/12/31 Projecto Estratégico - UI 674 - 2011-2012
PEst-OE/QUI/UI0674/2011
Universidade da Madeira, Portugal

Universidade da Madeira Centro de Química da Madeira, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2009/01/01 - 2013/12/31 BIOPHARMAC – Development of Biotechnological and Pharmaceutical Industries based on the biodiversity of Macaronesia
INTERREG MAC/1/M104
INTERREG MAC/1/M104
Investigador
Universidade da Madeira Centro de Química da Madeira, Portugal
Interreg Europe
Concluído
2006/01/01 - 2009/12/31 BIOPOLIS - Construindo uma bio-região europeia
05/MAC/2.3/C14
Investigador responsável
Universidade da Madeira Centro de Química da Madeira, Portugal
Interreg Europe
Concluído
2004/01 - 2007/01 CLAYCATS - Modified Porto Santo Clays as catalysts for liquid phase organic reactions Fundação para a Ciência e a Tecnologia, I.P.
Produções

Publicações

Artigo em conferência
  1. Castilho, Paula. "Reconversión de descartes agroalimentarios en ambientes insulares". Trabalho apresentado em SIMPOSIO RED CYTED 323RT0142: “ECONOMÍA CIRCULAR EN SISTEMAS DE PRODUCCIÓN AGROALIMENTARIOS DE IBEROAMÉRICA, Buenos Aires, 2023.
    Publicado
  2. Pereira, Verónica Raquel Sousa; Figueira, Onofre; Spínola, Vítor; Cardoso, Miguel; Castilho, Paula. "Valorization of Orange Peel Waste by Green Consecutive Extraction of Pectin and Hesperidin". Trabalho apresentado em Phytochemaical Society of Europe - Young Scientist Meeting, Paris, 2023.
    Publicado
  3. Castilho, Paula. "Resíduos da indústria agroalimentar como fonte de biopesticidas". Trabalho apresentado em Workshop: Desenvolvimento da Plataforma Macaronésia de Biopesticidas Botânicos, Ponta Delgada, 2023.
  4. Ferreira, Rui; Castilho, Paula. "Aplicação de protocolos de avaliação da actividade antifúngica e insecticida de óleos essenciais". Trabalho apresentado em Workshop: Desenvolvimento da Plataforma Macaronésia de Biopesticidas Botânicos, Ponta Delgada, 2023.
    Publicado
  5. Ferreira, Rui; Castilho, Paula. "Aromatic herbs – from Mediterranean cuisine to allies in pest control". Trabalho apresentado em 10º Encontro Anual CQM, Funchal, 2023.
  6. Figueira, Onofre; Castilho, Paula. "Membranes for Biomedical Applications: Investigating the Potential of Pectin and Chitosan". Trabalho apresentado em 10º Encontro Anual CQM, Funchal, 2023.
    Publicado
  7. Pereira, Verónica Raquel Sousa; Figueira, Onofre; Castilho, Paula. "Hesperidin as a potential biopesticide for environmental applications: extraction, purity determination, and formulation". Trabalho apresentado em 10º Encontro Anual CQM, Funchal, 2023.
  8. Castilho, Paula. "Valorização de resíduos da indústria Agroalimentar – a problemática das ilhas.". Trabalho apresentado em I Congreso de Innovación Social, La Plata, 2023.
    Publicado
  9. Castilho, Paula. "Waste from food industry as source of (bio)pesticidal substances". Trabalho apresentado em Sustainable and Precision Agriculture Symposium, La Laguna, 2022.
  10. Ferreira, Rui; Castilho, Paula. "Chemical screening and antifungal activity of Origanum vulgari and Thymus vulgari essential Oils against Botrytis cinereum and Erysiphe plant pathogens". Trabalho apresentado em Sustainable and Precision Agriculture Symposium, La Laguna, 2022.
    Publicado
Artigo em revista
  1. Pereira, Verónica Raquel Sousa; Figueira, Onofre; Castilho, Paula C.. "Flavonoids as Insecticides in Crop Protection—A Review of Current Research and Future Prospects". Plants 13 6 (2024): 776. http://dx.doi.org/10.3390/plants13060776.
    Acesso aberto • Publicado • 10.3390/plants13060776
  2. Pereira, Verónica; Figueira, Onofre; Castilho, Paula. ""Hesperidin: A Flavanone with Multifaceted Applications in the Food, Animal Feed, and Environmental Fields". (2024)". Phytochemistry Reviews (2024):
    Em revisão
  3. Camara, José S.; Perestrelo, Rosa; Ferreira, Rui; Berenguer, Cristina; Pereira, Jorge; Castilho, Paula. "Plant-derived terpenoids: a plethora of bioactive compounds with several health functions and industrial applications. A comprehensive approach". Food Research International (2024):
    Em revisão
  4. Figueira, Onofre; Pereira, Verónica; Castilho, Paula C.. "A Two-Step Approach to Orange Peel Waste Valorization: Consecutive Extraction of Pectin and Hesperidin". Foods 12 20 (2023): 3834. http://dx.doi.org/10.3390/foods12203834.
    Acesso aberto • Publicado • 10.3390/foods12203834
  5. Martins, Gonçalo Nuno; Angela Daniela Carboni; Ayelén Amelia Hugo; Castilho, Paula C; Gomez-Zavaglia, Andrea; Martins, Gonçalo Nuno; Carboni, Angela Daniela; et al. Autor correspondente: Gomez-Zavaglia, Andrea. "Chickpeas and lentils' soaking and cooking wastewaters repurposed for growing lactic acid bacteria". Foods 12 12 (2023): 2324. https://www.mdpi.com/2304-8158/12/12/2324.
    Aceite para publicação • 10.3390/foods12122324
  6. Ygor Ferreira Garcia da Costa; Eulogio José Llorent-Martínez; Laura Silva Fernandes; Pedro Henrique Santos de Freitas; Elita Scio; Orlando Vieira de Sousa; Paula Cristina Castilho; Maria Silvana Alves. "Phenolics Profiling by HPLC-DAD-ESI/MSn of the Scientific Unknown Polygonum hydropiperoides Michx. and Its Antioxidant and Anti-Methicillin-Resistant Staphylococcus aureus Activities". Plants (2023): https://doi.org/10.3390/plants12081606.
    10.3390/plants12081606
  7. Carboni, Angela; Martins, Gonçalo N.; Gomez-Zavaglia, Andrea; Castilho, Paula C.; Angela D. Carboni; Gonçalo N. Martins; Andrea Gómez-Zavaglia; Paula C. Castilho. "Lactic Acid Bacteria in the Production of Traditional Fermented Foods and Beverages of Latin America". Fermentation (2023): http://hdl.handle.net/10400.13/5537.
    10.3390/fermentation9040315
  8. José João Caires Serina; Paula Cristina Machado Ferreira Castilho; Serina, José João Caires; Castilho, Paula Cristina Machado Ferreira. "Using polyphenols as a relevant therapy to diabetes and its complications, a review". Critical Reviews in Food Science and Nutrition (2022): https://doi.org/10.1080/10408398.2021.1927977.
    10.1080/10408398.2021.1927977
  9. Rui Ferreira; Sílvia Lourenço; André Lopes; Carlos Andrade; José S. Câmara; Paula Castilho; Rosa Perestrelo; et al. "Evaluation of Fatty Acids Profile as a Useful Tool towards Valorization of By-Products of Agri-Food Industry". Foods (2021): https://doi.org/10.3390/foods10112867.
    10.3390/foods10112867
  10. Vítor Spínola; Paula C. Castilho; Spínola, Vítor; Castilho, Paula C.. "Assessing the In Vitro Inhibitory Effects on Key Enzymes Linked to Type-2 Diabetes and Obesity and Protein Glycation by Phenolic Compounds of Lauraceae Plant Species Endemic to the Laurisilva Forest". Molecules 26 7 (2021): 2023-2023. https://doi.org/10.3390/molecules26072023.
    10.3390/molecules26072023
  11. Fernandes, Laura Silva; Costa, Ygor Ferreira Garcia da; Bessa, Martha Eunice de; Ferreira, Adriana Lucia Pires; Corrêa, José Otávio do Amaral; Del-Vechio Vieira, Glauciemar; Sousa, Orlando Vieira de; et al. "Metabolic profiling and antibacterial activity of Eryngium pristis Cham. & Schltdl. - prospecting for its use in the treatment of bacterial infections". Archives of Pharmacy and Pharmaceutical Sciences (2021): http://hdl.handle.net/10400.13/4676.
    10.29328/journal.apps.1001027
  12. Ideia, Pedro; Esposti, Lorenzo Degli; Miguel, Carla Caseiro; Adamiano, Alessio; Iafisco, Michele; Castilho, Paula C; Pedro Ideia; et al. "Extraction and characterization of hydroxyapatite-based materials from grey triggerfish skin and black scabbardfish bones". International Journal of Applied Ceramic Technology (2021): http://hdl.handle.net/10400.13/4672.
    10.1111/ijac.13625
  13. Maria Micaela Ureta; Gonçalo Nuno Martins; Onofre Figueira; Pedro Filipe Pires; Paula Cristina Castilho; Andrea Gomez-Zavaglia. "Recent advances in ß-galactosidase and fructosyltransferase immobilization technology". Critical Reviews in Food Science and Nutrition (2020): https://doi.org/10.1080/10408398.2020.1783639.
    10.1080/10408398.2020.1783639
  14. Gonçalo N. Martins; Vítor Spínola; Paula C. Castilho; Martins, Gonçalo N.; Spínola, Vítor; Castilho, Paula C.. "Release of adsorbed ferulic acid in simulated gastrointestinal conditions". European Food Research and Technology (2020): https://doi.org/10.1007/s00217-020-03489-w.
    10.1007/s00217-020-03489-w
  15. Chloé Placines; Viana Castañeda-Loaiza; Maria João Rodrigues; Catarina G. Pereira; Azzurra Stefanucci; Adriano Mollica; Gokhan Zengin; et al. "Phenolic Profile, Toxicity, Enzyme Inhibition, In Silico Studies, and Antioxidant Properties of Cakile maritima Scop. (Brassicaceae) from Southern Portugal". Plants 9 2 (2020): 142-142. https://doi.org/10.3390/plants9020142.
    10.3390/plants9020142
  16. Vítor Spínola; Eulogio J. Llorent-Martínez; Paula C. Castilho; Spínola, Vítor; Llorent-Martínez, Eulogio J.; Castilho, Paula C.. "Inhibition of a-amylase, a-glucosidase and pancreatic lipase by phenolic compounds of Rumex maderensis (Madeira sorrel). Influence of simulated gastrointestinal digestion on hyperglycaemia-related damage linked with aldose reductase activity and protein glycation". LWT 118 (2020): 108727-108727. https://doi.org/10.1016/j.lwt.2019.108727.
    10.1016/j.lwt.2019.108727
  17. Ideia, Pedro; Sousa-Ferreira, Ivo; Castilho, Paula C.; Pedro Ideia; Ivo Sousa-Ferreira; Paula C. Castilho. "A novel and simpler alkaline hydrolysis methodology for extraction of ferulic acid from brewer’s spent grain and its (partial) purification through adsorption in a synthetic resin". Foods (2020): http://hdl.handle.net/10400.13/4278.
    10.3390/foods9050600
  18. Castilho, Paula; Khan, Haroon; Ullah, Hammad; Castilho, Paula Cristina Machado Ferreira; Gomila, Antoni Sureda; D'Onofrio, Grazia; Filosa, Rosanna; et al. "Targeting NF-¿B signaling pathway in cancer by dietary polyphenols". Critical Reviews in Food Science and Nutrition (2019): http://dx.doi.org/10.1080/10408398.2019.1661827.
    10.1080/10408398.2019.1661827
  19. Spínola, Vítor; Pinto, Joana; Llorent-Martínez, Eulogio J.; Castilho, Paula C.. "Changes in the phenolic compositions of Elaeagnus umbellata and Sambucus lanceolata after in vitro gastrointestinal digestion and evaluation of their potential anti-diabetic properties". Food Research International 122 (2019): 283-294. http://dx.doi.org/10.1016/j.foodres.2019.04.030.
    Publicado • 10.1016/j.foodres.2019.04.030
  20. Castilho, Paula. "Fish Processing Industry Residues: A Review of Valuable Products Extraction and Characterization Methods". Waste and Biomass Valorization (2019): http://dx.doi.org/10.1007/s12649-019-00739-1.
    10.1007/s12649-019-00739-1
  21. Castilho, Paula; Martins, Gonçalo N.; Ureta, Maria Micaela; Tymczyszyn, E. Elizabeth; Castilho, Paula C.; Gomez-Zavaglia, Andrea. "Technological Aspects of the Production of Fructo and Galacto-Oligosaccharides. Enzymatic Synthesis and Hydrolysis". Frontiers in Nutrition (2019): http://dx.doi.org/10.3389/fnut.2019.00078.
    10.3389/fnut.2019.00078
  22. Serina, J.; Fernandes, M.X.; Castilho, P.C.. "Effects of hydroxycinnamic acids on the glycolysis pathway". South African Journal of Botany 120 (2019): 219-229. http://dx.doi.org/10.1016/j.sajb.2018.06.016.
    Publicado • 10.1016/j.sajb.2018.06.016
  23. Spínola, Vítor; Pinto, Joana; Llorent-Martínez, Eulogio J.; Tomás, Helena; Castilho, Paula C.. "Evaluation of Rubus grandifolius L. (wild blackberries) activities targeting management of type-2 diabetes and obesity using in vitro models". Food and Chemical Toxicology 123 (2019): 443-452. http://hdl.handle.net/10400.13/2476.
    Publicado • 10.1016/j.fct.2018.11.006
  24. Spínola, Vítor; Llorent-Martínez, Eulogio J.; Castilho, Paula C.. "Polyphenols of Myrica faya inhibit key enzymes linked to type II diabetes and obesity and formation of advanced glycation end-products (in vitro): Potential role in the prevention of diabetic complications". Food Research International 116 (2019): 1229-1238. http://hdl.handle.net/10400.13/3202.
    Publicado • 10.1016/j.foodres.2018.10.010
  25. Spínola, Vítor; Pinto, Joana; Llorent-Martínez, Eulogio J.; Castilho, Paula C.. "Changes in the phenolic compositions of Elaeagnus umbellata and Sambucus lanceolata after in vitro gastrointestinal digestion and evaluation of their potential anti-diabetic properties". (2019): http://hdl.handle.net/10400.13/3199.
    10.1016/j.foodres.2019.04.030
  26. Quintana, Gabriel; Spínola, Vítor; Martins, Gonçalo N.; Gerbino, Esteban; Gómez-Zavaglia, Andrea; Castilho, Paula C.. "Release of health-related compounds during in vitro gastro-intestinal digestion of okara and okara fermented with Lactobacillus plantarum". (2019): http://hdl.handle.net/10400.13/3195.
    10.1007/s13197-019-04140-7
  27. Gomez-Zavaglia, Andrea; Passot, Stéphanie; Pénicaud, Caroline; Castilho, Paula; Simões, Pedro Nuno; Ropers, Marie Hélène; Perret, Bruno; et al. "Preserving bacteria with oligosaccharides and eco-friendly processes (Premium)". Cryobiology 85 (2018): 172-173. http://dx.doi.org/10.1016/j.cryobiol.2018.10.203.
    Publicado • 10.1016/j.cryobiol.2018.10.203
  28. Spínola, Vítor; Pinto, Joana; Castilho, Paula C.. "Hypoglycemic, anti-glycation and antioxidant in vitro properties of two Vaccinium species from Macaronesia: A relation to their phenolic composition". Journal of Functional Foods 40 (2018): 595-605. http://dx.doi.org/10.1016/j.jff.2017.12.002.
    Publicado • 10.1016/j.jff.2017.12.002
  29. Spínola, Vítor; Castilho, Paula C.. "Madeira moneywort (Sibthorpia peregrina L.) as a new source of verbascoside and its derivatives with potential phyto-pharmaceutical applications". Natural Product Research (2018): 1-5. http://hdl.handle.net/10400.13/3205.
    Publicado • 10.1080/14786419.2018.1474354
  30. Spínola, Vítor; Llorent-Martínez, Eulogio J.; Castilho, Paula C.. "Antioxidant polyphenols of Madeira sorrel (Rumex maderensis): How do they survive to in vitro simulated gastrointestinal digestion?". Food Chemistry 259 (2018): 105-112. http://hdl.handle.net/10400.13/3204.
    Publicado • 10.1016/j.foodchem.2018.03.112
  31. Llorent-Martínez, Eulogio J.; Spínola, Vítor; Castilho, Paula C.. "Phenolic profiles of Lauraceae plant species endemic to Laurisilva forest: A chemotaxonomic survey". Industrial Crops and Products 107 (2017): 1-12. http://dx.doi.org/10.1016/j.indcrop.2017.05.023.
    Publicado • 10.1016/j.indcrop.2017.05.023
  32. Spínola, Vítor; Castilho, Paula C.. "Evaluation of Asteraceae herbal extracts in the management of diabetes and obesity. Contribution of caffeoylquinic acids on the inhibition of digestive enzymes activity and formation of advanced glycation end-products ( in vitro )". Phytochemistry 143 (2017): 29-35. http://dx.doi.org/10.1016/j.phytochem.2017.07.006.
    Publicado • 10.1016/j.phytochem.2017.07.006
  33. Pinto, Joana; Spínola, Vítor; Llorent-Martínez, Eulogio J.; Fernández-de Córdova, María Luisa; Molina-García, Lucía; Castilho, Paula C.. "Polyphenolic profile and antioxidant activities of Madeiran elderberry (Sambucus lanceolata) as affected by simulated in vitro digestion". Food Research International 100 (2017): 404-410. http://dx.doi.org/10.1016/j.foodres.2017.03.044.
    Publicado • 10.1016/j.foodres.2017.03.044
  34. Llorent-Martínez, Eulogio J.; Spínola, Vítor; Castilho, Paula C.. "Evaluation of the inorganic content of six underused wild berries from Portugal: Potential new sources of essential minerals". Journal of Food Composition and Analysis 59 (2017): 153-160. http://dx.doi.org/10.1016/j.jfca.2017.02.016.
    Publicado • 10.1016/j.jfca.2017.02.016
  35. Castilho, Paula. "Caffeoylquinic acids as inhibitors for HIV-I protease and HIV-I Integrase. A Molecular docking study". SDRP Journal of Computational Chemistry & Molecular Modelling 1 2 (2017): http://dx.doi.org/10.25177/jccmm.1.2.1.
    Acesso aberto • Publicado • 10.25177/jccmm.1.2.1
  36. Spínola, Vítor; Llorent-Martínez, Eulogio J.; Gouveia-Figueira, Sandra; Castilho, Paula C.. "Ulex europaeus: from noxious weed to source of valuable isoflavones and flavanones". Industrial Crops and Products 90 (2016): 9-27. http://dx.doi.org/10.1016/j.indcrop.2016.06.007.
    Publicado • 10.1016/j.indcrop.2016.06.007
  37. Spínola, Vítor; Castilho, Paula C.. "Phytochemical Profile, Chemotaxonomic Studies, andIn VitroAntioxidant Activities of Two Endemisms from Madeira Archipelago:Melanoselinum decipiensandMonizia edulis(Apiaceae)". Chemistry & Biodiversity 13 10 (2016): 1290-1306. http://dx.doi.org/10.1002/cbdv.201600039.
    Publicado • 10.1002/cbdv.201600039
  38. Spínola, Vítor; Pinto, Joana; Castilho, Paula C.. "In vitro studies on the effect of watercress juice on digestive enzymes relevant to type 2 diabetes and obesity and antioxidant activity". Journal of Food Biochemistry 41 1 (2016): e12335. http://dx.doi.org/10.1111/jfbc.12335.
    Publicado • 10.1111/jfbc.12335
  39. Ribeiro Carrott, M.M.L.; Cansado, I.P.P.; Carrott, P.J.M.; Russo, P.A.; Castilho, P.; Fernandes, C.; Catrinescu, C.; Breen, C.. "Porosity in ion-exchanged and acid activated clays evaluated using n-nonane pre-adsorption". Microporous and Mesoporous Materials 232 (2016): 238-247. http://dx.doi.org/10.1016/j.micromeso.2016.06.030.
    Publicado • 10.1016/j.micromeso.2016.06.030
  40. Branco, P.C.; Dionísio, A.M.; Torrado, I.; Carvalheiro, F.; Castilho, P.C.; Duarte, L.C.. "Autohydrolysis of Annona cherimola Mill. seeds: Optimization, modeling and products characterization". Biochemical Engineering Journal 104 (2015): 2-9. http://dx.doi.org/10.1016/j.bej.2015.06.006.
    Publicado • 10.1016/j.bej.2015.06.006
  41. Gouveia-Figueira, Sandra C.; Castilho, Paula C.. "Phenolic screening by HPLC–DAD–ESI/MSn and antioxidant capacity of leaves, flowers and berries of Rubus grandifolius Lowe". Industrial Crops and Products 73 (2015): 28-40. http://dx.doi.org/10.1016/j.indcrop.2015.03.022.
    Publicado • 10.1016/j.indcrop.2015.03.022
  42. Catrinescu, C.; Fernandes, C.; Castilho, P.; Breen, C.. "Selective methoxylation of a-pinene to a-terpinyl methyl ether over Al3+ ion-exchanged clays". Applied Catalysis A: General 489 (2015): 171-179. http://dx.doi.org/10.1016/j.apcata.2014.10.028.
    Publicado • 10.1016/j.apcata.2014.10.028
  43. Llorent-Martinez, E.J.; Spinola, V.; Gouveia, S.; Castilho, P.C.. "HPLC-ESI-MSn characterization of phenolic compounds, terpenoid saponins, and other minor compounds in Bituminaria bituminosa". Industrial Crops and Products 69 (2015): 80-90. http://www.scopus.com/inward/record.url?eid=2-s2.0-84923017046&partnerID=MN8TOARS.
    10.1016/j.indcrop.2015.02.014
  44. Spínola, V.; Pinto, J.; Castilho, P.C.. "Identification and quantification of phenolic compounds of selected fruits from Madeira Island by HPLC-DAD-ESI-MSn and screening for their antioxidant activity". Food Chemistry 173 (2015): 14-30. http://www.scopus.com/inward/record.url?eid=2-s2.0-84908389377&partnerID=MN8TOARS.
    10.1016/j.foodchem.2014.09.163
  45. Llorent-Martínez, E.J.; Gouveia, S.; Castilho, P.C.. "Analysis of phenolic compounds in leaves from endemic trees from Madeira Island. A contribution to the chemotaxonomy of Laurisilva forest species". Industrial Crops and Products 64 (2015): 135-151. http://www.scopus.com/inward/record.url?eid=2-s2.0-84920155468&partnerID=MN8TOARS.
    10.1016/j.indcrop.2014.10.068
  46. Spínola, V.; Perestrelo, R.; Câmara, J.S.; Castilho, P.C.. "Establishment of Monstera deliciosa fruit volatile metabolomic profile at different ripening stages using solid-phase microextraction combined with gas chromatography-mass spectrometry". Food Research International 67 (2015): 409-417. http://www.scopus.com/inward/record.url?eid=2-s2.0-84916886839&partnerID=MN8TOARS.
    10.1016/j.foodres.2014.11.055
  47. Vilcocq, Léa; Spinola, Vitor; Moniz, Patricia; Duarte, Luís C.; Carvalheiro, Florbela; Fernandes, César; Castilho, Paula. "Acid-modified clays as green catalysts for the hydrolysis of hemicellulosic oligosaccharides". Catalysis Science & Technology 5 8 (2015): 4072-4080. http://dx.doi.org/10.1039/c5cy00195a.
    Publicado • 10.1039/c5cy00195a
  48. Vilcocq, L.; Castilho, P.C.; Carvalheiro, F.; Duarte, L.C.. "Hydrolysis of oligosaccharides over solid acid catalysts: A review". ChemSusChem 7 4 (2014): 1010-1019. http://www.scopus.com/inward/record.url?eid=2-s2.0-84898059662&partnerID=MN8TOARS.
    10.1002/cssc.201300720
  49. Spínola, V.; Llorent-Martínez, E.J.; Gouveia, S.; Castilho, P.C.. "Myrica faya: A new source of antioxidant phytochemicals". Journal of Agricultural and Food Chemistry 62 40 (2014): 9722-9735. http://www.scopus.com/inward/record.url?eid=2-s2.0-84907942521&partnerID=MN8TOARS.
    10.1021/jf503540s
  50. Spínola, V.; Llorent-Martínez, E.J.; Castilho, P.C.. "Determination of vitamin C in foods: Current state of method validation". Journal of Chromatography A 1369 (2014): 2-17. http://www.scopus.com/inward/record.url?eid=2-s2.0-84909633891&partnerID=MN8TOARS.
    10.1016/j.chroma.2014.09.087
  51. Gouveia-Figueira, S.C.; Gouveia, C.A.; Carvalho, M.J.; Rodrigues, A.I.; Nording, M.L.; Castilho, P.C.. "Antioxidant capacity, cytotoxicity and antimycobacterial activity of madeira archipelago endemic Helichrysum dietary and medicinal plants". Antioxidants 3 4 (2014): 713-729. http://www.scopus.com/inward/record.url?eid=2-s2.0-84928561788&partnerID=MN8TOARS.
    10.3390/antiox3040713
  52. Gouveia, S.C.; Castilho, P.C.. "Artemisia annua L.: Essential oil and acetone extract composition and antioxidant capacity". Industrial Crops and Products 45 (2013): 170-181. http://www.scopus.com/inward/record.url?eid=2-s2.0-84872257652&partnerID=MN8TOARS.
    10.1016/j.indcrop.2012.12.022
  53. Gouveia, S.; Gonçalves, J.; Castilho, P.C.. "Characterization of phenolic compounds and antioxidant activity of ethanolic extracts from flowers of Andryala glandulosa ssp. varia (Lowe ex DC.) R.Fern., an endemic species of Macaronesia region". Industrial Crops and Products 42 1 (2013): 573-582. http://www.scopus.com/inward/record.url?eid=2-s2.0-84864036475&partnerID=MN8TOARS.
    10.1016/j.indcrop.2012.06.040
  54. Spínola, V.; Mendes, B.; Câmara, J.S.; Castilho, P.C.. "Effect of time and temperature on vitamin C stability in horticultural extracts. UHPLC-PDA vs iodometric titration as analytical methods". LWT - Food Science and Technology 50 2 (2013): 489-495. http://www.scopus.com/inward/record.url?eid=2-s2.0-84867852479&partnerID=MN8TOARS.
    10.1016/j.lwt.2012.08.020
  55. Catrinescu, C.; Fernandes, C.; Castilho, P.; Breen, C.; Carrott, M.M.L.R.; Cansado, I.P.P.. "Selective methoxylation of limonene over ion-exchanged and acid-activated clays". Applied Catalysis A: General 467 (2013): 38-46. http://www.scopus.com/inward/record.url?eid=2-s2.0-84881160223&partnerID=MN8TOARS.
    10.1016/j.apcata.2013.07.012
  56. Gonçalves, J.; Silva, C.L.; Castilho, P.C.; Câmara, J.S.. "An attractive, sensitive and high-throughput strategy based on microextraction by packed sorbent followed by UHPLC-PDA analysis for quantification of hydroxybenzoic and hydroxycinnamic acids in wines". Microchemical Journal 106 (2013): 129-138. http://www.scopus.com/inward/record.url?eid=2-s2.0-84868300172&partnerID=MN8TOARS.
    10.1016/j.microc.2012.05.037
  57. Spínola, V.; Mendes, B.; Câmara, J.S.; Castilho, P.C.. "An improved and fast UHPLC-PDA methodology for determination of L-ascorbic and dehydroascorbic acids in fruits and vegetables. Evaluation of degradation rate during storage". Analytical and Bioanalytical Chemistry 403 4 (2012): 1049-1058. http://www.scopus.com/inward/record.url?eid=2-s2.0-84861228323&partnerID=MN8TOARS.
    10.1007/s00216-011-5668-x
  58. Gouveia, S.C.; Castilho, P.C.. "Phenolic composition and antioxidant capacity of cultivated artichoke, Madeira cardoon and artichoke-based dietary supplements". Food Research International 48 2 (2012): 712-724. http://www.scopus.com/inward/record.url?eid=2-s2.0-84863672855&partnerID=MN8TOARS.
    10.1016/j.foodres.2012.05.029
  59. Viciolle, E.; Castilho, P.; Rosado, C.. "In vitro and in vivo assessment of the effect of Laurus novocanariensis oil and essential oil in human skin". International Journal of Cosmetic Science 34 6 (2012): 546-550. http://www.scopus.com/inward/record.url?eid=2-s2.0-84868209636&partnerID=MN8TOARS.
    10.1111/j.1468-2494.2012.00745.x
  60. Gouveia, S.; Castilho, P.C.. "Helichrysum monizii lowe: Phenolic composition and antioxidant potential". Phytochemical Analysis 23 1 (2012): 72-83. http://www.scopus.com/inward/record.url?eid=2-s2.0-82955247988&partnerID=MN8TOARS.
    10.1002/pca.1326
  61. Gouveia, S.C.; Castilho, P.C.. "Validation of a HPLC-DAD-ESI/MS n method for caffeoylquinic acids separation, quantification and identification in medicinal Helichrysum species from Macaronesia". Food Research International 45 1 (2012): 362-368. http://www.scopus.com/inward/record.url?eid=2-s2.0-84855558127&partnerID=MN8TOARS.
    10.1016/j.foodres.2011.09.023
  62. Castilho, P.C.; Savluchinske-Feio, S.; Weinhold, T.S.; Gouveia, S.C.. "Evaluation of the antimicrobial and antioxidant activities of essential oils, extracts and their main components from oregano from Madeira Island, Portugal". Food Control 23 2 (2012): 552-558. http://www.scopus.com/inward/record.url?eid=2-s2.0-80053131642&partnerID=MN8TOARS.
    10.1016/j.foodcont.2011.08.031
  63. Gouveia, S.; Castilho, P.C.. "Characterisation of phenolic acid derivatives and flavonoids from different morphological parts of Helichrysum obconicum by a RP-HPLC-DAD-(-)-ESI-MS n method". Food Chemistry 129 2 (2011): 333-344. http://www.scopus.com/inward/record.url?eid=2-s2.0-79960023051&partnerID=MN8TOARS.
    10.1016/j.foodchem.2011.04.078
  64. Gouveia, S.; Castilho, P.C.. "Antioxidant potential of Artemisia argentea L'Hér alcoholic extract and its relation with the phenolic composition". Food Research International 44 6 (2011): 1620-1631. http://www.scopus.com/inward/record.url?eid=2-s2.0-79958247102&partnerID=MN8TOARS.
    10.1016/j.foodres.2011.04.040
  65. Branco, P.C.; Castilho, P.C.; Rosa, M.F.; Ferreira, J.. "Characterization of Annona cherimola mill. Seed oil from Madeira Island: A possible biodiesel feedstock". JAOCS, Journal of the American Oil Chemists' Society 87 4 (2010): 429-436. http://www.scopus.com/inward/record.url?eid=2-s2.0-84755161236&partnerID=MN8TOARS.
    10.1007/s11746-009-1513-1
  66. Gouveia, S.C.; Castilho, P.C.. "Characterization of phenolic compounds in Helichrysum melaleucum by high-performance liquid chromatography with on-line ultraviolet and mass spectrometry detection". Rapid Communications in Mass Spectrometry 24 13 (2010): 1851-1868. http://www.scopus.com/inward/record.url?eid=2-s2.0-77954247740&partnerID=MN8TOARS.
    10.1002/rcm.4585
  67. Gouveia, S.C.; Castilho, P.C.. "Analysis of phenolic compounds from different morphological parts of helichrysum devium by liquid chromatography with on-line UV and electrospray ionization mass spectrometric detection". Rapid Communications in Mass Spectrometry 23 24 (2009): 3939-3953. http://www.scopus.com/inward/record.url?eid=2-s2.0-71949123790&partnerID=MN8TOARS.
    10.1002/rcm.4335
  68. Castilho, P.C.; Weinhold, T.S.; Gouveia, S.C.; Savluchinske-Feio, S.; Pereira, P.T.; Rodrigues, A.I.; Venâncio, F.. "Chemical composition and bioactivity of essential oils and extracts from oregano from madeira Island, Portugal". Acta Horticulturae 826 (2009): 213-220. http://www.scopus.com/inward/record.url?eid=2-s2.0-70350073865&partnerID=MN8TOARS.
  69. Louh, G.N.; Lannang, A.M.; Mbazoa, C.D.; Tangmouo, J.G.; Komguem, J.; Castilho, P.; Ngninzeko, F.N.; et al. "Polyanxanthone A, B and C, three xanthones from the wood trunk of Garcinia polyantha Oliv.". Phytochemistry 69 4 (2008): 1013-1017. http://www.scopus.com/inward/record.url?eid=2-s2.0-38949111735&partnerID=MN8TOARS.
    10.1016/j.phytochem.2007.10.002
  70. Castilho, P.C.; Gouveia, S.C.; Rodrigues, A.I.. "Quantification of artemisinin in Artemisia annua extracts by 1H-NMR". Phytochemical Analysis 19 4 (2008): 329-334. http://www.scopus.com/inward/record.url?eid=2-s2.0-48049092999&partnerID=MN8TOARS.
    10.1002/pca.1053
  71. Luna-Herrera, J.; Costa, M.C.; González, H.G.; Rodrigues, A.I.; Castilho, P.C.. "Synergistic antimycobacterial activities of sesquiterpene lactones from Laurus spp". Journal of Antimicrobial Chemotherapy 59 3 (2007): 548-552. http://www.scopus.com/inward/record.url?eid=2-s2.0-34248140692&partnerID=MN8TOARS.
    10.1093/jac/dkl523
  72. Castilho, P.; Liu, K.; Rodrigues, A.I.; Feio, S.; Tomi, F.; Casanova, J.. "Composition and antimicrobial activity of the essential oil of Clinopodium ascendens (Jordan) Sampaio from Madeira". Flavour and Fragrance Journal 22 2 (2007): 139-144. http://www.scopus.com/inward/record.url?eid=2-s2.0-33847070768&partnerID=MN8TOARS.
    10.1002/ffj.1771
  73. Fernandes, C.; Catrinescu, C.; Castilho, P.; Russo, P.A.; Carrott, M.R.; Breen, C.. "Catalytic conversion of limonene over acid activated Serra de Dentro (SD) bentonite". Applied Catalysis A: General 318 (2007): 108-120. http://www.scopus.com/inward/record.url?eid=2-s2.0-33846010748&partnerID=MN8TOARS.
    10.1016/j.apcata.2006.10.048
  74. Macchioni, F.; Perrucci, S.; Cioni, P.; Morelli, I.; Castilho, P.; Cecchi, F.. "Composition and acaricidal activity of Laurus novocanariensis and Laurus nobilis essential oils against Psoroptes cuniculi". Journal of Essential Oil Research 18 1 (2006): 111-114. http://www.scopus.com/inward/record.url?eid=2-s2.0-31644439143&partnerID=MN8TOARS.
  75. Catrinescu, C.; Fernandes, C.; Castilho, P.; Breen, C.. "Influence of exchange cations on the catalytic conversion of limonene over Serra de Dentro (SD) and SAz-1 clays. Correlations between acidity and catalytic activity/selectivity". Applied Catalysis A: General 311 1-2 (2006): 172-184. http://www.scopus.com/inward/record.url?eid=2-s2.0-33747102330&partnerID=MN8TOARS.
    10.1016/j.apcata.2006.06.023
  76. Catrinescu, C.; Fernandes, C.; Castilho, P.; Breen, C.; Carrott, M.. "Porto santo clays as environmentally friendly catalysts for the conversion of renewable terpene feedstocks. Limonene aromatization to p-cymene". Environmental Engineering and Management Journal 5 3 (2006): 275-284. http://www.scopus.com/inward/record.url?eid=2-s2.0-85040836066&partnerID=MN8TOARS.
  77. Ferrari, B.; Castilho, P.; Tomi, F.; Rodrigues, A.I.; do Ceu Costa, M.; Casanova, J.. "Direct identification and quantitative determination of costunolide and dehydrocostuslactone in the fixed oil of Laurus novocanariensis by 13C-NMR spectroscopy". Phytochemical Analysis 16 2 (2005): 104-107. http://www.scopus.com/inward/record.url?eid=2-s2.0-17344366120&partnerID=MN8TOARS.
    10.1002/pca.825
  78. Castilho, P.C.; Costa, M.D.C.; Rodrigues, A.; Partidário, A.. "Characterization of laurel fruit oil from Madeira Island, Portugal". JAOCS, Journal of the American Oil Chemists' Society 82 12 (2005): 863-868. http://www.scopus.com/inward/record.url?eid=2-s2.0-33947404430&partnerID=MN8TOARS.
    10.1007/s11746-005-1156-4
  79. Castilho, P.C.; Costa, M.D.C.; Rodrigues, A.; Branco, P.C.; Costa, M.. "Characterization of triacylglycerols in madeira laurel oil by HPLC-atmospheric pressure chemical ionization-MS". JAOCS, Journal of the American Oil Chemists' Society 81 10 (2004): 913-919. http://www.scopus.com/inward/record.url?eid=2-s2.0-10244224138&partnerID=MN8TOARS.
  80. Castilho, P.C.M.F.; Crampton, M.R.; Yarwood, J.. "Infrared spectroscopic studies of hydrogen bonding in substituted nitrophenols: substituent and solvent effects". Vibrational Spectroscopy 3 3 (1992): 167-180. http://www.scopus.com/inward/record.url?eid=2-s2.0-44049118470&partnerID=MN8TOARS.
    10.1016/0924-2031(92)87001-V
  81. Castilho, P.C.M.F.; Crampton, M.R.; Yarwood, J.. "The basicity of alkali metal methoxides in methanol. The effects of ion association on methoxide additions to activated anisoles". Journal of the Chemical Society, Perkin Transactions 2 5 (1991): 639-643. http://www.scopus.com/inward/record.url?eid=2-s2.0-37049082977&partnerID=MN8TOARS.
Capítulo de livro
  1. Martins, Gonçalo Nuno; Figueira, Onofre; Castilho, Paula C. "lmmobilization of ß-galactosidase in calcium alginate beads". In Basic Protocols in Encapsulation of Food Ingredients, editado por Gómez-Zavaglia, Andrea. Springer US, 2021.
    No prelo • 10.1007/978-1-0716-1649-9
  2. Sandra C. Gouveia; Spínola, Vítor; Castilho, Paula C. "Phenolic compounds and antioxidant capacity of medicinal plants: a review". In Medicinal Plants: Antioxidant Properties, Traditional Uses and Conservation Strategies, 1-40. Nova Science Publishers, 2013.
    Publicado
Poster em conferência
  1. Martins, Gonçalo Nuno; Gomez-Zavaglia, Andrea; Castilho, Paula C. Autor correspondente: Martins, Gonçalo Nuno. "Imobilização de enzimas para a valorização de sub-produtos alimentares". Trabalho apresentado em Oficinas de Doutoramento - A Química é Divertida, 2023.
  2. Castilho, Paula; Gouveia-Figueira, Sandra; Rijo, Patricia. "Bioactive Phloroglucinols from Helichrysum devium Lowe". Trabalho apresentado em PSE Natural Drug Discovery, Current Approach and Future Perspectives, 2023.
  3. Martins, Gonçalo Nuno; Maria Guerrero Sanchez; Angela D. Carboni; Fernanda Fonseca; Sonia Campoy; Gomez-Zavaglia, Andrea; Castilho, Paula C. "Stabilization of Lactiplantibacillus plantarum WCFS1 during freezing, freeze-drying, and storage using legume wastewater extracts". Trabalho apresentado em 3rd Food Chemistry Conference, 2023.
  4. Martins, Gonçalo Nuno; Angela D. Carboni; Ayelén Amelia Hugo; Castilho, Paula C; Gomez-Zavaglia, Andrea. "Extraction, obtention, and yielding of galacto-oligosaccharides from chickpea and lentils". Trabalho apresentado em 3rd Food Chemistry Conference, 2023.
  5. Pereira, Verónica Raquel Sousa; Figueira, Onofre; Castilho, Paula. "Hesperidin-loaded nanoparticles as a promising sustainable release system for environmental applications". Trabalho apresentado em XXXI International Congress in Polyphenols ICP2023 em Topic 6: Biomaterials, green chemistry & circular bioeconomy, 2023.
  6. Figueira, Onofre; Pereira, Verónica Raquel Sousa; Castilho, Paula. "Hesperidin and pectin sequential extraction for orange waste valorization". Trabalho apresentado em XXXI International Congress in Polyphenols ICP2023 in the Topic 6: Biomaterials, green chemistry & circular bioeconomy, 2023.
  7. Figueira, Onofre; Pereira, Verónica Raquel Sousa; Castilho, Paula. "PEC Membranes Based on Pectin-Chitosan and Pectin-Chitosan-Wax for Biomedical Applications". Trabalho apresentado em Phytochemical Society of Europe - Young Scientist Meeting, 2023.
  8. Martins, Gonçalo Nuno; Angela D. Carboni; Castilho, Paula C; María Cecilia Puppo; Cristina Ferrero; Gomez-Zavaglia, Andrea. "Impacto económico del descarte de aguas provenientes del procesamiento de legumbres". Trabalho apresentado em 1º Congreso Nacional de Innovación Social, 2023.
  9. Angela Daniela Carboni; Martins, Gonçalo Nuno; Cristina Ferrero; María Cecilia Puppo; Castilho, Paula C. Autor correspondente: Castilho, Paula C. "Techno-functional and physicochemical properties of lentil flour with different particle sizes". Trabalho apresentado em XVI Encontro de Química dos Alimentos, 2022.
  10. Angela Daniela Carboni; Martins, Gonçalo Nuno; Ayelén Amelia Hugo; Gomez-Zavaglia, Andrea; Castilho, Paula C. Autor correspondente: Castilho, Paula C. "Application of soaking and cooking waters as prebiotics". Trabalho apresentado em XVI Encontro de Química dos Alimentos, 2022.
  11. Figueira, Onofre; Martins, Gonçalo Nuno; Gomez-Zavaglia, Andrea; Castilho, Paula C. "Fructo- and galacto-oligosaccharides purification: the hard step". Trabalho apresentado em 2nd Food Chemistry Conference, 2019.
  12. Figueira, Onofre; Martins, Gonçalo Nuno; Castilho, Paula C. "Plant-based FOS and GOS: So easy, yet so difficult". 2019.
  13. Martins, Gonçalo Nuno; Spínola, Vítor; Castilho, Paula C. "Driving ferulic acid to the small bowel by desorption from resin". Trabalho apresentado em XXVI Encontro Anual da Sociedade Portuguesa de Química, 2019.
Resumo em conferência
  1. Castilho, Paula C; Martins, Gonçalo Nuno; Javier González Perez; Carina Jacinta Caires; Vieira, Mariana. Autor correspondente: Castilho, Paula C. "Purification of GOS (and FOS): oxidation vs fermentation methods". Trabalho apresentado em XVIII Congreso Argentino de Ciencia y Tecnologia de Alimentos, Buenos Aires, 2023.
    Publicado
  2. Javier González; Martins, Gonçalo Nuno; Gomez-Zavaglia, Andrea; Castilho, Paula C. "Purification of galacto-oligosaccharides by enzymatic reaction with glucose oxidase". Trabalho apresentado em 10th CQM Annual Meeting, Funchal, 2023.
    Publicado
  3. Martins, Gonçalo Nuno; Angela Daniela Carboni; Ayelén Amelia Hugo; Gomez-Zavaglia, Andrea; Castilho, Paula C. Autor correspondente: Castilho, Paula C. "Discards from legumes as bacteria cryoprotectants". Trabalho apresentado em 9th CQM Annual Meeting, Funchal, 2022.
    Publicado
  4. Martins, Gonçalo Nuno; Figueira, Onofre; Castilho, Paula C. Autor correspondente: Castilho, Paula C. "Immobilization of ß-galactosidase in calcium alginate beads". Trabalho apresentado em 8th CQM Annual Meeting, Funchal, 2021.
    Publicado
  5. Figueira, Onofre; Martins, Gonçalo Nuno; Castilho, Paula C. "Extraction, purification and quantification of fructooligosaccharides in Yacon (Smallanthus sonchifolius) roots and syrup". Trabalho apresentado em 6th CQM Annual Meeting, Porto Moniz, 2019.
  6. Martins, Gonçalo Nuno; Maria Isaura Gouveia Lourenço; Gomez-Zavaglia, Andrea; Castilho, Paula C. "Galactoligosaccharides from chickpea seeds". Trabalho apresentado em 6th CQM Annual Meeting, Porto Moniz, 2019.
  7. Martins, Gonçalo Nuno; Castilho, Paula C. "Delivery of ferulic acid during an in vitro digestion simulation". Trabalho apresentado em 5th CQM Annual Meeting, Funchal, 2018.
Atividades

Orientação

Título / Tema
Papel desempenhado
Curso (Tipo)
Instituição / Organização
2017 - Atual FishValue - from marine byproducts to biomaterials
Orientador
Química (Doutoramento)
Universidade da Madeira Centro de Química da Madeira, Portugal
2021/09/01 - 2025/09/30 Immobilizing enzymes for the valorization of food by-products
Orientador
3º ciclo Química (Doutoramento)
Universidade da Madeira, Portugal
2021/04/01 - 2025/04/30 Encapsulating bioactive Phenolic Compounds from Madeira Island Flora using food waste materials
Orientador
3º ciclo Química (Doutoramento)
Universidade da Madeira, Portugal
2021/01/02 - 2024/12/31 Valorization of biomass byproducts as sources of biopesticides through development and application of ecofriendly processes
Orientador
Química (Doutoramento)
Universidade da Madeira Centro de Química da Madeira, Portugal
2021/01/02 - 2024/12/31 Acyl-quinic acids and their action on gut enzymes and bacteria
Orientador
Química (Doutoramento)
Universidade da Madeira Centro de Química da Madeira, Portugal
2020/03/01 - 2024/02/28 Caffeoylquinic acids from metabolic regulators to bio-pesticides, in silico and in vitro studies
Orientador
3º ciclo Química (Doutoramento)
Universidade da Madeira Centro de Química da Madeira, Portugal
2022/10/01 - 2023/10/16 From Citrus Waste to a Promising Biopesticide: Hesperidin Extraction, Nanoformulation, and Bioactivity Evaluation
Orientador
Bioquímica Aplicada (Mestrado)
Universidade da Madeira, Portugal
2020/07/01 - 2021/06/30 Potencial antibiótico e anti-inflamatório tópico de extractos metanólicos obtidos de folhas e frutos de Rubus grandifolium Lowe (Rosaceae Juss.)
Coorientador
Academic Master degree within the programme of post-graduation in Pharmaceutical Sciences (Mestrado)
Universidade Federal de Juiz de Fora, Brasil
2019/10/01 - 2021/01/20 Profile analysis of oligosaccharides in vegetal matrices: extraction optimization and inulin hydrolysis
Orientador
Bioquímica Aplicada (Mestrado)
Universidade da Madeira Centro de Química da Madeira, Portugal
2017 - 2018 Release of resin-bound ferulic acid during na in vitro digestion simulation and antioxidant activity evaluation
Orientador
Bioquímica Aplicada (Mestrado)
Universidade da Madeira Centro de Química da Madeira, Portugal
2013 - 2018 Nutraceuticals and functional foods for diabetes and obesity control
Orientador
Química (Doutoramento)
Universidade da Madeira Centro de Química da Madeira, Portugal
2016 - 2017 Estudo da Composição e das Propriedades Bioativas de plantas produtoras de bagas.
Orientador
Bioquímica Aplicada (Mestrado)
Universidade da Madeira Centro de Química da Madeira, Portugal
2015 - 2017 Stabilization of labile flavonoids by immobilization on solid matrices
Orientador
Bioquímica Aplicada (Mestrado)
Universidade da Madeira Centro de Química da Madeira, Portugal
2015 - 2016 Resíduos da Indústria Agro-Alimentar como possíveis fontes de ácido ferúlico.
Orientador
Bioquímica Aplicada (Mestrado)
Universidade da Madeira Centro de Química da Madeira, Portugal
2007 - 2016 Integrated valorization of Anona Cherimola Mill. seeds
Orientador
Química (Doutoramento)
Universidade da Madeira Centro de Química da Madeira, Portugal
2013 - 2014/01/13 Enzymatic inhibitory activity of hydroxycinnamates (HCs): in silico studies
Orientador
Bioquímica Aplicada (Mestrado)
Universidade da Madeira Faculdade de Ciências Exatas e da Engenharia, Portugal
2014 - 2014 Produção de Monoglicéridos através de Catalisadores de Argila.
Orientador
Bioquímica Aplicada (Mestrado)
Universidade da Madeira Centro de Química da Madeira, Portugal
2012/09/01 - 2013/05/20 Novas metodologias para a determinação do conteúdo de ácido árcobico em alimentos frescos
Orientador
Bioquímica Aplicada (Mestrado)
Universidade da Madeira Centro de Química da Madeira, Portugal
2012 - 2013 Valorização do óleo essencial das bagas de Laurus novocanariensis : avaliação da extracção, estabilidade oxidativa e efeitos na aplicação cutânea
Orientador
Bioquímica Aplicada (Mestrado)
Universidade da Madeira Faculdade de Ciências Exatas e da Engenharia, Portugal
2006 - 2011 Phytochemical Studies of Bioactive Asteraceae Plants Endemic From Madeira Archipelago
Orientador
Química (Doutoramento)
Universidade da Madeira Centro de Química da Madeira, Portugal
2009 - 2010 Caracterização e isolamento de compostos bioactivos do fungo Laurobasidium lauri (Madre de louro)
Orientador
Bioquímica Aplicada (Mestrado)
Universidade da Madeira Faculdade de Ciências Exatas e da Engenharia, Portugal
2002 - 2007 Argilas de Origem Portuguesa como Catalisadores da Aromatização do Limoneno
Orientador
Química (Doutoramento)
Universidade da Madeira, Portugal

Arbitragem científica em revista

Nome da revista (ISSN) Editora
2020/04/01 - 2024/03/23 Molecules MDPI
2019/03/23 - 2024/03/23 Plants MDPI
2019/03/23 - 2024/03/23 Industrial Crops & Products (0926-6690) Elsevier
2019/03/23 - 2021/03/23 Food Chemistry (0308-8146) Elsevier