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Filipa Alexandra Delgado Siopa completed her Ph.D. degree in December 2011 from New University of Lisbon, Portugal and Chemistry degree in 2003 by Universidade de Lisboa Faculdade de Ciências. Since 2012, Filipa Siopa work in the Bioorganic Chemistry group in iMed.ULisbon, with Prof. Carlos A. M. Afonso at Faculty of Pharmacy of the University of Lisbon (FFUL). First as a Postdoctoral Fellow with an FCT scholarship, then between 2019 and 2014 has a Junior Research. In 2024, she assumed the role of Assistant Professor at FFUL. Her main research focus is the synthesis and valorization of bicyclic-aziridines prepared by photochemical transformation of pyridinium salts. The application of this photochemical transformations under continuous-flow is also a topic of her research. To lead these projectsFilipa Siopa improved/developed silks in the fields of Flow Chemistry, Photochemistry, Analytic Chemistry, Organic Chemistry, Bioorganic Chemistry, Structural Analysis, Medicinal Chemistry and Drug Discovery. Filipa Siopa is also interested in C-H activation, which allowed a Scientific Exchange Visits to Prof. Giovanni Poli Group at Sorbonne Université (Paris, France) Filipa Siopa Published 27 articles in journals. Has 4 section(s) of books. Organized 4 event(s). Participated in 7 event(s). Has received 2 awards and/or honors. Participates and/or participated as PhD Student Fellow in 1 project(s), Pos-doctoral Fellow in 2 project(s), Research Fellow in 1 project(s) and Researcher in 6 project(s). Works in the area(s) of Exact Sciences with emphasis on Chemical Sciences. In their professional activities interacted with 92 collaborator(s) co-authorship of scientific papers.
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Identificação

Identificação pessoal

Nome completo
Filipa Alexandra Delgado Siopa

Nomes de citação

  • Siopa, Filipa

Identificadores de autor

Ciência ID
6A16-150F-A9F9
ORCID iD
0000-0002-4514-9154

Endereços de correio eletrónico

  • filipasiopa@ff.ul.pt (Profissional)

Telefones

Telefone
  • 217946400 (Profissional)

Moradas

  • Faculdade de Farmácia da UL. Av. Prof. Gama Pinto , 1649-003 , Lisboa, Lisboa, Portugal (Profissional)

Websites

Domínios de atuação

  • Ciências Exatas - Química

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Francês Utilizador independente (B2) Utilizador elementar (A1) Utilizador elementar (A1) Utilizador independente (B2)
Espanhol; Castelhano Utilizador independente (B1) Utilizador independente (B1) Utilizador elementar (A1) Utilizador independente (B1)
Formação
Grau Classificação
2011
Concluído
 Ph.D. in Chemistry (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
"Protein and DNA modification by quinones derived from catecholamines. " (TESE/DISSERTAÇÃO)
 Passed by unanimously
2003
Concluído
 Chemistry (Licenciatura)
Universidade de Lisboa Faculdade de Ciências, Portugal
"Investigation of acid zeolites for new routes of synthesis of sugar" (TESE/DISSERTAÇÃO)
 15
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2019/03/01 - 2024/12/19 Investigador (Investigação) Universidade de Lisboa Faculdade de Farmácia, Portugal

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento 		Empregador
2024/12/20 - Atual Professor Auxiliar (Docente Universitário) Universidade de Lisboa Faculdade de Farmácia, Portugal

Outros

Categoria Profissional
Instituição de acolhimento 		Empregador
2013/01/01 - 2019/02/28 Post-Doc Research (SFRH / BPD / 88666 / 2012) Working with Prof. Carlos A. M. Afonso Valorization of bicyclic-aziridines synthesized by photochemical transformation of pyridinium salts under continuou Universidade de Lisboa Faculdade de Farmácia, Portugal
2012/03/01 - 2012/12/31 Research fellowship (BI) in the project "Polymes photochromic activated by two-photon excitation" (PTDC/CTM-POL/114367/2009). Supervisor Prof. Carlos Afonso Universidade de Lisboa Faculdade de Farmácia, Portugal
2011/11/01 - 2012/02/29 Research fellowship (BI) in the project “Resídues elimination using biocatalysis in ionic liquids with eukaryotic organisms” (PTDC/QUI/71331/2006). Supervisor Prof. Carlos Afonso Universidade de Lisboa Faculdade de Farmácia, Portugal
2007/11/01 - 2011/10/31 PhD Student (SFRH/BD/39171/2007), supervisor Prof. Paula Branco and Prof. Matilde Marques Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2006/09/01 - 2007/10/31 Teacher in middle and high school Colégio Santo André, Portugal
2005/03/01 - 2006/08/31 Research fellowship (BI) in the project “Hot Solutes” (FP6-2002-SME-1) supervisor Prof. Christopher Maycock. Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2004/09/01 - 2005/02/28 Research fellowship (BI) in the project “Synthesis of Metal Centers with Pharmacological Significance” (POCTI/QUI/43415/2001), supervisor Prof. Armando Pombeiro Universidade de Lisboa Instituto Superior Técnico, Portugal
2004/01/11 - 2004/07/09 Trainee F Hoffmann-La Roche AG, Suiça
2002/09/10 - 2003/10/31 Trainee last year degree under the supervision of Prof. Amélia Pilar Rauter Universidade de Lisboa Faculdade de Ciências, Portugal
Projetos

Bolsa

Designação Financiadores
2019/02/01 - 2019/04/30 Erasmus + Program - Pd-Catalyzed Ring Opening of Bicyclic Aziridines Prepared by Photochemical Transformation of Pyridinium Salt Under Continuous Flow
P LISBOA109
Sorbonne Université, França

Institut Parisien de Chimie Moléculaire, França
Erasmus Plus
Concluído
2013/01/01 - 2019/02/28 New synthetic methodology for the synthesis of carbocycles
SFRH / BPD / 88666 / 2012
Bolseiro de Pós-Doutoramento
Concluído
2013/07/01 - 2015/12 GenoSep: Removal of Genotoxic Impurities from Active Pharmaceutical Ingredients
info:eu-repo/grantAgreement/FCT/3599-PPCDT/128708/PT
Universidade de Lisboa Instituto Superior Técnico, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2011/04/01 - 2014/09/30 Two-photon activated photochromic polymers
PTDC/CTM-POL/114367/2009
Bolseiro de Pós-Doutoramento
Universidade de Lisboa Instituto Superior Técnico, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2008/01/01 - 2012/12/31 Waste Elimination using Ionic Liquid Bio-Engineered Eukariotic Organisms
PTDC/QUI/71331/2006
Bolseiro de Investigação
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2007/11/01 - 2011/12/20 Protein and DNA modification by quinones derived from catecholamines.
SFRH/BD/39171/2007
Bolseiro de Doutoramento
Fundação para a Ciência e a Tecnologia, Portugal
Concluído

Outro

Designação Financiadores
2022/01/01 - Atual Smart Ionic Liquids For Valorization of Food residues.
SMIL4FOOD
Investigador
2021/01/01 - Atual Straightening training, research and innovation capacities in the valorization of bio-renewable resource
GA: 9551996
Investigador
Universidade de Lisboa Faculdade de Farmácia, Portugal
 European Commission
Em curso
2020/07/01 - Atual SafeS4Life - Long-term active surface protection to SARS-CoV-2 contamination
Projeto n. 483
Investigador
Fundação para a Ciência e a Tecnologia
Em curso
2020/01/01 - Atual COST Action, CA18224 “Green Chemical Engineering Network towards upscaling sustainable processes” (GREENERING)
CA18224
Investigador
Em curso
2018/11/01 - Atual Tomorrow's Materials and Clean Technologies
CAPES - PrInt UFSM Edital No. 41/2017
Investigador
Universidade Federal de Santa Maria, Brasil
Em curso
2018/03/01 - Atual COST Action, CA15106 "C-H Activation in Organic Synthesis" (CHAOS)
CA15106
Investigador
Concluído
2013/01/01 - Atual Funding of RD Units Strategic Plan - 2013/2015 - OE
UID/DTP/04138/2019
Investigador
2023/01/01 - 2026/12/31 New edge in the therapeutics of Parkinson´s disease from seaweeds
2022.09196.PTDC)
Investigador
Em curso
2023/01/01 - 2024/06/30 “Merging photochemical and asymmetric synthesis to access new chiral aminocyclopentitols"
2022.08559.PTDC
Investigador responsável
Em curso
2018/01/01 - 2019/12/31 From furan based biomass building blocks to valuable molecules
PESSOA 2018/2019 (Proc.441.00 França and PHC PESSOA 2018 No 40875QJ)
Investigador
Universidade de Lisboa Faculdade de Farmácia, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2015/01/01 - 2019/12/31 Project Integrated valorization of lignocellulosic agroindustrial waste to furan based building blocks
ELAC2014/BEE-0341
Investigador
Universidade de Lisboa Faculdade de Farmácia, Portugal
Em curso
Produções

Publicações

Artigo em revista
  1. M. J. Perry; Ana P. Francisco; Afonso, Carlos A. M.. "Batch and Continuous Synthesis of 5,5-Diphenylhydantoin, an Active Pharmaceutical Ingredient". J. Chem. Educ. (2025): https://doi.org/10.1021/acs.jchemed.4c01286.
    10.1021/acs.jchemed.4c01286
  2. Sousa, Dídia; Fortunato, Milene A. G.; Silva, Joana; Pingo, Mónica; Martins, Alice; Afonso, Carlos A. M.; Pedrosa, Rui; Siopa, Filipa; Alves, Celso. "Sphaerococcenol A Derivatives: Design, Synthesis, and Cytotoxicity". Marine Drugs 22 9 (2024): 408. https://doi.org/10.3390/md22090408.
    10.3390/md22090408
  3. Mori, Alessia; Crespo Monteiro, Mariana Isabel; Siopa, Filipa; Poli, Giovanni; Oble, Julie. "Selective C3- or C5-Borylation of furfural derivatives: Enabling the synthesis of tri- and tetra-substituted furan Analogues". Tetrahedron Chem 11 (2024): 100079. https://doi.org/10.1016/j.tchem.2024.100079.
    10.1016/j.tchem.2024.100079
  4. Mariana Crespo Monteiro,; Siopa, Filipa. Autor correspondente: Siopa, Filipa. "Colaboração entre Giovanni Poli e Portugal em Reações Catalisadas por Metais de Transição". Química 48 172 (2024): 33-40. https://b-quimica.spq.pt/magazines/BSPQuimica/709/article/30002768.
    Aceite para publicação
  5. Mariana, Monteiro; João, Vale. "2-Azabicyclo[3.2.1]octane scaffold: Synthesis and Applications". Organic & Biomolecular Chemistry (2024): https://pubs.rsc.org/en/Content/ArticleLanding/2024/OB/D4OB00199K.
    10.1039/D4OB00199K
  6. Vale, João R.; Fortunato, Milene A. G.; Andrade, Késsia H. S.; Rocha, Ângelo M. R.; Afonso, Carlos A. M.; Siopa, Filipa. "From Pyridine to (-)-Agelastatin A". Advanced Synthesis & Catalysis (2023): http://dx.doi.org/10.1002/adsc.202300560.
    10.1002/adsc.202300560
  7. Siopa, Filipa; Afonso, C. A. M.; Fortunato, Milene; Vale, João Rafael Campos do. "Combining photochemical transformation of pyridinium salt with kinetic enzymatic resolution towards the total synthesis of (-)-agelastatin A". ChemRxiv (2022): https://chemrxiv.org/engage/chemrxiv/article-details/62f6bf3de650df5f8c23f2ad.
    Publicado
  8. "(1R,4S,5S)-5-((3-Hydroxypropyl)amino)-4-((1-methyl-1H-tetrazol-5-yl)thio)cyclopent-2-en-1-ol". Molbank 2 (2021):
  9. Oliveira, João A.C.; Kiala, Gredy; Siopa, Filipa; Bernard, Aurélie; Gontard, Geoffrey; Oble, Julie; Afonso, CarlosA.M.; Poli, Giovanni. "Palladium-catalyzed allylic substitution between C-based nucleophiles and 6-azabicyclo[3.1.0]-hex-3-en-2-oxy derivatives: A new selectivity paradigm". Tetrahedron (2020): 131182. "in Press" http://dx.doi.org/10.1016/j.tet.2020.131182.
    10.1016/j.tet.2020.131182
  10. João M. J. M. Ravasco; Carlos M. Monteiro; Filipa Siopa; Alexandre F. Trindade; Julie Oble; Giovanni Poli; Svilen P. Simeonov; Carlos A. M. Afonso. "Creating Diversity from Biomass: A Tandem Bio/Metal-Catalysis towards Chemoselective Synthesis of Densely Substituted Furans". ChemSusChem (2019): https://doi.org/10.1002/cssc.201902051.
    10.1002/cssc.201902051
  11. Milene A. G. Fortunato; Chi-Phong Ly; Filipa Siopa; Carlos A. M. Afonso. "Process Intensification for the Synthesis of 6-Allyl-6-azabicyclo[3.1.0]hex-3-en-2-ol from 1-Allylpyridinium Salt Using a Continuous UV-Light Photoflow Approach". Methods and Protocols 2 3 (2019): 67-67. https://doi.org/10.3390/mps2030067.
    10.3390/mps2030067
  12. Filipa Siopa; Valérie-Anne Ramis Cladera; Carlos Alberto Mateus Afonso; Julie Oble; Giovanni Poli. "Ruthenium-Catalyzed C-H Arylation and Alkenylation of Furfural Imines with Boronates". European Journal of Organic Chemistry 2018 44 (2018): 6101-6106. https://doi.org/10.1002/ejoc.201800767.
    10.1002/ejoc.201800767
  13. Siopa, F.; António, J.P.M.; Afonso, C.A.M.. "Flow-Assisted Synthesis of Bicyclic Aziridines via Photochemical Transformation of Pyridinium Salts". Organic Process Research and Development 22 4 (2018): 551-556. http://www.scopus.com/inward/record.url?eid=2-s2.0-85045849984&partnerID=MN8TOARS.
    10.1021/acs.oprd.8b00036
  14. Soromenho, M.R.C.; Siopa, F.; Afonso, C.A.M.; Esperança, J.M.S.S.. "Enhanced photoconversion of 1,2-bis(2-methyl-1-benzothiophene-3-yl)perfluorocyclopentene in ionic liquid solutions". Journal of Photochemistry and Photobiology A: Chemistry 358 (2018): 44-50. http://www.scopus.com/inward/record.url?eid=2-s2.0-85043402020&partnerID=MN8TOARS.
    10.1016/j.jphotochem.2018.03.002
  15. Siopa, F.; Frade, R.F.M.; Diniz, A.; Andrade, J.M.; Nicolai, M.; Meirinhos, A.; Lucas, S.D.; et al. "Acetylcholinesterase Choline-Based Ionic Liquid Inhibitors: In Vitro and in Silico Molecular Docking Studies". ACS Omega 3 12 (2018): 17145-17154. http://www.scopus.com/inward/record.url?eid=2-s2.0-85058533771&partnerID=MN8TOARS.
    10.1021/acsomega.8b02347
  16. Sintra, T.E.; Nasirpour, M.; Siopa, F.; Rosatella, A.A.; Gonçalves, F.; Coutinho, J.A.P.; Afonso, C.A.M.; Ventura, S.P.M.. "Ecotoxicological evaluation of magnetic ionic liquids". Ecotoxicology and Environmental Safety 143 (2017): 315-321. http://www.scopus.com/inward/record.url?eid=2-s2.0-85019664958&partnerID=MN8TOARS.
    10.1016/j.ecoenv.2017.05.034
  17. Siopa, F.; Figueiredo, T.; Frade, R.F.M.; Neto, I.; Meirinhos, A.; Reis, C.P.; Sobral, R.G.; Afonso, C.A.M.; Rijo, P.. "Choline-Based Ionic Liquids: Improvement of Antimicrobial Activity". ChemistrySelect 1 18 (2016): 5909-5916. http://www.scopus.com/inward/record.url?eid=2-s2.0-85041924710&partnerID=MN8TOARS.
    10.1002/slct.201600864
  18. Vale, J.R.; Siopa, F.; Branco, P.S.; Afonso, C.A.M.. "Ring Opening of 6-Azabicyclo[3.1.0]hex-3-en-2-ols in Water under Mild Conditions". European Journal of Organic Chemistry 2016 11 (2016): 2048-2053. http://www.scopus.com/inward/record.url?eid=2-s2.0-84962747064&partnerID=MN8TOARS.
    10.1002/ejoc.201501468
  19. Rosatella, A.A.; Siopa, F.; Frade, R.F.M.; Afonso, C.A.M.. "New low viscous cholinium-based magnetic ionic liquids". New Journal of Chemistry 40 4 (2016): 3124-3129. http://www.scopus.com/inward/record.url?eid=2-s2.0-84964584603&partnerID=MN8TOARS.
    10.1039/c5nj03165f
  20. Hartmann, D.O.; Shimizu, K.; Siopa, F.; Leitão, M.C.; Afonso, C.A.M.; Canongia Lopes, J.N.; Silva Pereira, C.. "Plasma membrane permeabilisation by ionic liquids: a matter of charge". Green Chemistry 17 9 (2015): 4587-4598. http://www.scopus.com/inward/record.url?eid=2-s2.0-84940842689&partnerID=MN8TOARS.
    10.1039/c5gc01472g
  21. Mariz, I.F.A.; Siopa, F.; Rodrigues, C.A.B.; Afonso, C.A.M.; Chen, X.; Martinho, J.M.G.; Maçôas, E.M.S.. "A 1,3,5-triazine based polymer as a nonlinear near-infrared antenna for two-photon activated volumetric optical memory devices". Journal of Materials Chemistry C 3 41 (2015): 10775-10782. http://www.scopus.com/inward/record.url?eid=2-s2.0-84945143632&partnerID=MN8TOARS.
    10.1039/c5tc02085a
  22. e Silva, F.A.; Siopa, F.; Figueiredo, B.F.H.T.; Gonçalves, A.M.M.; Pereira, J.L.; Gonçalves, F.; Coutinho, J.A.P.; Afonso, C.A.M.; Ventura, S.P.M.. "Sustainable design for environment-friendly mono and dicationic cholinium-based ionic liquids". Ecotoxicology and Environmental Safety 108 (2014): 302-310. http://www.scopus.com/inward/record.url?eid=2-s2.0-84921689496&partnerID=MN8TOARS.
    10.1016/j.ecoenv.2014.07.003
  23. Frade, R.F.M.; Simeonov, S.; Rosatella, A.A.; Siopa, F.; Afonso, C.A.M.. "Toxicological evaluation of magnetic ionic liquids in human cell lines". Chemosphere 92 1 (2013): 100-105. http://www.scopus.com/inward/record.url?eid=2-s2.0-84876988633&partnerID=MN8TOARS.
    10.1016/j.chemosphere.2013.02.047
  24. Barbosa, D.J.; Capela, J.P.; Oliveira, J.M.; Silva, R.; Ferreira, L.M.; Siopa, F.; Branco, P.S.; et al. "Pro-oxidant effects of Ecstasy and its metabolites in mouse brain synaptosomes". British Journal of Pharmacology 165 4 B (2012): 1017-1033. http://www.scopus.com/inward/record.url?eid=2-s2.0-84856316830&partnerID=MN8TOARS.
    10.1111/j.1476-5381.2011.01453.x
  25. Siopa, F.; Pereira, A.S.; Ferreira, L.M.; Matilde Marques, M.; Branco, P.S.. "Synthesis of catecholamine conjugates with nitrogen-centered bionucleophiles". Bioorganic Chemistry 44 (2012): 19-24. http://www.scopus.com/inward/record.url?eid=2-s2.0-84866395166&partnerID=MN8TOARS.
    10.1016/j.bioorg.2012.05.002
  26. Siopa, F.. "CsOH·H2O in organic synthesis". Synlett 18 (2009): 3048-3049. http://www.scopus.com/inward/record.url?eid=2-s2.0-72049128066&partnerID=MN8TOARS.
    10.1055/s-0029-1218292
  27. Faria, T.Q.; Mingote, A.; Siopa, F.; Ventura, R.; Maycock, C.; Santos, H.. "Design of new enzyme stabilizers inspired by glycosides of hyperthermophilic microorganisms". Carbohydrate Research 343 18 (2008): 3025-3033. http://www.scopus.com/inward/record.url?eid=2-s2.0-55049115053&partnerID=MN8TOARS.
    10.1016/j.carres.2008.08.030
  28. Rauter, A.P.; Almeida, T.; Xavier, N.M.; Siopa, F.; Vicente, A.I.; Lucas, S.D.; Marques, J.P.; et al. "Acid zeolites as efficient catalysts for O- and S-glycosylation". Journal of Molecular Catalysis A: Chemical 275 1-2 (2007): 206-213. http://www.scopus.com/inward/record.url?eid=2-s2.0-34548203168&partnerID=MN8TOARS.
    10.1016/j.molcata.2007.06.002
  29. Borges, N.; Gonçalves, L.G.; Rodrigues, M.V.; Siopa, F.; Ventura, R.; Maycock, C.; Lamosa, P.; Santos, H.. "Biosynthetic pathways of inositol and glycerol phosphodiesters used by the hyperthermophile Archaeoglobus fulgidus in stress adaptation". Journal of Bacteriology 188 23 (2006): 8128-8135. http://www.scopus.com/inward/record.url?eid=2-s2.0-33751559039&partnerID=MN8TOARS.
    10.1128/JB.01129-06
Capítulo de livro
  1. Siopa, Filipa; Afonso, Carlos A. M.. "Pyridinium Salts as Valuable Synthetic Building Blocks". In Synthesis and Applications in Chemistry and Materials, 185-217. WORLD SCIENTIFIC, 2024.
    10.1142/9789811283215_0018
  2. Siopa, F.; Afonso, C. A. M.. "Synthesis of Benzopinacolone via Benzophenone Photoreduction Followed by Pinacol Rearrangement". In Comprehensive Organic Chemistry Experiments for the Laboratory Classroom, 697-700. The Royal Society of Chemistry: Cambridge, 2016.
    Publicado
  3. Siopa, Filipa; Candeias, N.; Afonso, C. A. M.. "Synthesis of the Antitumoral Drug 2,4,6-Tris(dimethylamino)-1,3,5-triazine via Sequential Nucleophilic Substitution". In Comprehensive Organic Chemistry Experiments for the Laboratory Classroom, 535-538. The Royal Society of Chemistry: Cambridge, 2016.
    Publicado
  4. Siopa, Filipa; Meirinhos, A. I. B.; Afonso, C. A. M.. "Hydroxyl Group Protection via Tetrahydropyranyl Ether Formation". In Comprehensive Organic Chemistry Experiments for the Laboratory Classroom, 241-244. The Royal Society of Chemistry: Cambridge, 2016.
Poster em conferência
  1. Crespo Monteiro, Mariana; Siopa, Filipa; Afonso, Carlos. Autor correspondente: Afonso, Carlos. "Pd-catalyzed cycloaddition of bicyclic aziridine with isocyanates (Med. Sci. Forum 2022, 14(1), 97)". Trabalho apresentado em The 8th International Electronic Conference on Medicinal Chemistry 2022, 2022.
  2. Milene A. G. Fortunato; Siopa, Filipa; Carlos Alberto Mateus Afonso. Autor correspondente: Carlos Alberto Mateus Afonso. "Production scale-up of a-hydroxycyclopenteno-aziridines with new home-made UV reactor and a flow parallel quartz tube reactor". Trabalho apresentado em 5th EuChemS Conference on Green and Sustainable Chemistry, 2021.
  3. Siopa, Filipa; Vera M.S. Isca; Rijo, Patrícia; Afonso, Carlos. "Molecular docking as a tool to design novel PKC-d modulators for colon cancer therapy". Trabalho apresentado em 2019 Sino-Portugal Forum on Traditional Medicine, Nanchang Jiangxi, China, November, 2019, 2019.
  4. Siopa, Filipa; Vera M. S. Isca; Rijo, Patrícia; Afonso, C.A.M.. "Molecular docking as a tool to design new royleanone derivatives for colon cancer therapy based on PKC-d modulation". Trabalho apresentado em 67th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research, in Innsbruck, Austria, 2019.
  5. Siopa, Filipa; Vera M. S. Isca; Rijo, Patrícia; Afonso, Carlos A. M.. "Structure-based drug design of royleanone derivatives from Plectranthus spp. as PKC-d modulators,". Trabalho apresentado em Natural Products in Drug Discovery and Human Health (NatProdDDH), Lisbon,, 2019.
  6. Siopa, Filipa; Milene A. G. Fortunato; Carlos, A.M. Afonso. "Flow assisted photochemical transformation of pyridinium salts". Trabalho apresentado em 4º Meeting of the College of Chemistry, 2019.
  7. Oliveira, João; Siopa, Filipa; Afonso, Carlos Alberto Mateus; Oble, Julie; Poli, Giovanni. "Pd-catalyzed Ring Opening of Bicyclic Aziridines Prepared by Flow Assisted Photochemical Transformation of Pyridinium Salts". Trabalho apresentado em 17èmes Rencontres de Chimie Organique, 2019.
  8. Siopa, Filipa; Afonso, C. A. M.; Oble, J.; Giovanni Poli. "Imine Furfurals for Ruthenium-Catalyzed Direct C3-H Arylations and Alkenylations". Trabalho apresentado em COST Action CA15106 (CHAOS) - Terragona, Spain, 2018.
  9. Siopa, Filipa; Cladera, V-A. R.; Afonso, Carlos A. M.; Julie Oble. "Imine Furfurals for Ruthenium-Catalyzed Direct C3-H Arylations and Alkenylations". Trabalho apresentado em BOSS XVI- 16th Belgian Organic Synthesis Symposium, 8-13 July 2018,, 2018.
  10. Siopa, Filipa; Cladera, V-A. R.; Afonso, Carlos; Oble, J.; Giovanni Poli. "Imine Furfurals for Ruthenium-Catalyzed Direct C3-H Arylations and Alkenylations". Trabalho apresentado em 10th iMed.ULisboa Postgraduated Student Meeting & 3rd i3du Meeting, 2018.
  11. Siopa, Filipa; Fortunato, M; António, J.P.M.; Vale, J.R.; Afonso, Carlos. "Flow assisted synthesis of possible bioactive carbocycles from pyridinium salts". Trabalho apresentado em 6th Portuguese Young Chemists Meeting (6th PYCheM), 2018.
  12. Siopa, Filipa; António, J.P.M.; Vale, J.R.. "Process intensification for the aziridine synthesis using continuous flow reactors". Trabalho apresentado em TRAMECH IX - 9th Trans Mediterranean Colloquium on Heterocyclic Chemistry, 2017.
  13. Siopa, Filipa; António, J.P.M.; Vale, J.R.; Afonso, Carlos. "Bicyclic aziridines synthesis by flow assisted photochemical transformation of pyridinium salts". Trabalho apresentado em 1º Meeting of the College of Chemistry, 2017.
  14. Siopa, Filipa; António, J.P.M.; Vale, J.R.; Afonso, Carlos. "Flow assisted synthesis of bicyclic aziridines via photochemical transformation of pyridinium salts". Trabalho apresentado em XXV National Meeting of the Portuguese Chemistry Society, 2017.
  15. Siopa, Filipa; António, J.P.M.; Vale, J.R.; Afonso, Carlos. "Development of a photochemical flow reactor for the conversion of pyridinium salts to bicyclic aziridines". Trabalho apresentado em 9th iMed.ULisboa Postgraduated Student Meeting & 2nd i3du Meeting, 2017.
  16. Siopa, Filipa; Meirinhos, A. I. B.; Frade, R.F.M.; Rijo, Patrícia; Afonso, C. A. M.. "Antimicrobial Activity and Toxicity Evaluation of Choline Analogues". Trabalho apresentado em 19th European Symposium on Organic Chemistry, 2015.
  17. Siopa, Filipa; Rosatella, A.A.; Afonso, C.A.M.. "Magnetic Ionic Liquids based on Choline – Synthesis and biological evaluation". Trabalho apresentado em 19th European Symposium on Organic Chemistry, 2015.
  18. Siopa, Filipa; Vale, J.R.; Branco, P. S; Afonso, Carlos A. M.. "Nucleophilic Ring-opening of Bicyclic Vinyl Azirinides under Physiological Conditions". Trabalho apresentado em 19th European Symposium on Organic Chemistry, 2015.
  19. Siopa, Filipa; Silva, Francisca A. e. "Designing non-toxic mono and dicationic cholinium-based ionic liquids". Trabalho apresentado em 6th International Conference of Ionic Liquids, 2015.
Pré-impressão
  1. Filipa Siopa; Maria Perry; Ana P. Francisco,; Carlos Afonso. "Batch and continuous synthesis of 5,5-diphenylhydantoin, an active pharmaceutical ingredient". 2024. https://doi.org/10.26434/chemrxiv-2024-rrp4p.
    10.26434/chemrxiv-2024-rrp4p
Resumo em conferência
  1. Monteiro, Mariana Crespo; Afonso, Carlos A. M.; Siopa, Filipa. "Pd-Catalyzed Cycloaddition of Bicyclic Aziridine with Isocyanates". 2022.
    10.3390/ecmc2022-13424
  2. Rijo, Patricia; Isca, Vera; Ntungwe, Epole; Tavares, Joana; Siopa, Filipa; Almeida, Joana; Saraiva, Lucilia; et al. "Design and molecular docking studies of new potential PKC-d activators based on royleanone scaffold". 2019.
    10.3390/ecmc2019-06297
Tese / Dissertação
  1. Siopa, Filipa Alexandra Delgado. "Modificação de proteínas e DNA por quinonas derivadas de catecolaminas". Doutoramento, 2011. http://hdl.handle.net/10362/8782.

Outros

Outra produção
  1. Sustainable design for environment-friendly mono and dicationic cholinium-based ionic liquids. Cholinium-based ionic liquids are receiving crescent interest in diverse areas of application given their biological compatibility and potential for industrial application. In this work, mono and dicationic cholinium ionic liquids as well as cholinium derivatives were synthesized and their toxicity assessed using the luminescent bacteria Vibrio fischeri. A range of cholinium derivatives was synthe. 2014. Silva, Francisca A. e; Siopa, Filipa; Figueiredo, Bruna F. H. T.; Goncalves, Ana M. M.; Pereira, Joana L.; Goncalves, Fernando; Coutinho, Joao A. P.; Afonso, Carlos A. M.; Ventura, Sonia P. M.. http://hdl.handle.net/10773/20511.
    10.1016/j.ecoenv.2014.07.003
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2023/03/09 Invited Oral Communication “Photochemical transformation of pyridinium salts” Siopa, F. (speaker), EnzIL - Biofriendly Decontamination of Chemical Warfare Agents (No G5713),
(Lisbon, Portugal)
2022/09/08 “Merging photoflow and Pd-catalysis to synthesized new aminocyclopentenes” Siopa, F. (speaker) 9th IUPAC International Conference on Green Chemistry (9th ICGC), 5 –9 September 2022,
(Athens , Grécia)
2022/08/28 “Combining photoflow of pyridinium salts with Pd-catalysis to access new aminocyclopentene” Siopa, F. (speaker), 8thEuChemS Chemistry Congress (ECC8), 28 August - 1September 2022
(Lisbon, Portugal)
2022/04/20 “Synthesis of new aminocyclopentenes via photoflow of pyridinium salts followed by Pd-catalysis” Siopa, F. (speaker), , 14th National Organic Chemistry Meeting & 7th National Medicinal Chemistry Meeting, 20-22 April 2022
(Costa da Caparica,, Portugal)
2022/03/22 Invited Oral Communication “Advantages Advantages of Pyridinium Salts continuous-flow in the Synthesis of New Aminocyclopentenes”, Siopa, F. Biomass4Synthons Mini-symposium, Sorbonne Université, 22 March 2022, Paris, France.
(Paris, França)
2022/02/16 Invited plenary “Photochemical transformation of pyridinium salts” Siopa, F. (speaker), Workshop - Biomass Valorization & Winter School – Photosynthesis and Photocatalysis,
14-16 February 2023 (Sofia, Bulgária)
2021/08/31 Application of photoflow on pyridinium salts: challenges and opportunities ISySyCat 2021
(Évora, Portugal)
2019/11/14 Turning Innovation in Pharmaceutical Research into Health and Education IMed.ULisboa MISSION 2018-22 , Create innovation in pharmaceutical research and apply it to the benefit of science and society Invited - Lisbon Area Postdoc Meeting 2019
(Costa da Caparica, Portugal)
2019/10/09 "Creating Diversity from Biomass: A Tandem Bio/Metal-Catalysis towards Chemoselective Synthesis of Densely Substituted Furans “ Invited - Synthesis and Catalysis Seminar and Workshop
(Costa da Caparica, Portugal)
2019/07/18 “Process intensification of bicyclic aziridine from pyridinium salts using a continuous UV-light photoflow approach" 4º Meeting of the College of Chemistry
(Lisbon, Portugal)
2018/12/07 Strategies to synthesized bioactive compounds Invited - PostDoc Seminar Series, iMed.ULisboa
(Lisbon, Portugal)
2018/06/27 Imine Furfurals for Ruthenium-Catalyzed Direct C3-H Arylations and Alkenylations 3º Meeting of the College of Chemistry
(Lisboa, Portugal)
2018/05/23 C3 Arylation of Furfural Derivatives via Catalytic C-H Bond Activation Invited - Ciclo de Conferências do Departaamento de Química
(Braga, Portugal)
2018/03/23 C3 Arylation of Furfural Derivatives via Catalytic C-H Bond Activation Invited - COST Action - CA15106 (CHAOS)
(Alcalá, Espanha)
2018/01/17 Batch versus Flow Photochemistry for the synthesis of bicyclic-aziridines from pyridinium salts: A Comparison of Productivity and Yield 12º National Organic Chemistry Meeting & 5º National Medicinal Chemistry Meeting
(Coimbra, Portugal)
2015/12/01 Ring-opening of alfa-hydroxy-cyclopentene-aziridines in water under mild conditions 11º Congress of Organic Chemistry and 4º Therapeutic Chemistry,
(Porto, Portugal)

Orientação

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2024/09/01 - Atual Advancing chemical synthesis by sustainable transition metal Catalysis (2024.01463.BDANA)
Coorientador
2021/10/01 - Atual Engenharia química de extratos de algas da costa portuguesa como fonte de compostos bioativos com atividade antitumoral e anti-inflamatória
Coorientador
2020/10/01 - Atual “Flow Chemistry as a tool for asymmetric synthesis of bioactive molecules”.
Coorientador
 Organic Chemistry (Doutoramento)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2024/01/03 - 2025/07/07 SYNTHESIS OF NEW COMPOUNDS WITH BIOACTIVE POTENTIAL FROM MARINE ALGAE EXTRACTS
Orientador
2020/10/01 - 2024/11/25 "Light as a powerful tool to create new synthons from aromatic building blocks“, (2020.04589.BD)
Orientador
 Organic Chemistry (Doutoramento)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2022/09/01 - 2023/10/20 Functionalization and biological evaluation of new abietane diterpenoids
Coorientador
2022/10/01 - 2023/09/20 Combining FlowPhotochemistry with functional group transformation as a tool to the synthesis of highly functionalize carbocycles
Orientador
 Erasmus Chemistry Master student from Università Degli Studi Dell’Insubria (Mestrado)
2022/02/01 - 2023/07/25 Transformation & Functionalization of dehydroabietic acid by C-H activation
Coorientador
2022/01/01 - 2022/12/20 Selective C–H Functionalization of Furfural and its Derivatives
Coorientador
2021/09/01 - 2022/11/28 Chemical engineered extracts of Portuguese biorenewable resources to the synthesis of diverse natural products hybrids towards new bioactive entities
Orientador
2022/02/01 - 2022/07/01 Transformation and functionalization of abietane diterpenoids
Coorientador
2019/09 - 2020/01 "Synthesis of bicyclic aziridines as intermediates for the total synthesis of compounds with potential anticancer activity"
Orientador
 Drug’s Synthesis laboratory classes (3rd year students of Pharmaceutical Sciences) (Licenciatura/Bacharelato)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2019/03 - 2019/12 "Pd-Catalyzed Ring Opening of Bicyclic Aziridines Prepared by Photochemical Transformation of Pyridinium Salt Under Continuous Flow"
Orientador
Universidade de Lisboa Faculdade de Farmácia, Portugal
2019/07/01 - 2019/07/31 Valorization of bicyclic vinyl aziridines prepared by photochemical transformation of pyridinium salts, using Metal catalysis
Orientador
 Internship from Sorbonne Université (Paris, France) (Licenciatura/Bacharelato)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2019/06 - 2019/07 “Pd-catalyzed ring-opening reaction of bicyclic aziridines”
Orientador
 Master Student from Sorbonne Université (Paris, France) (Mestrado)
Science Sorbonne Université, França
2018/09 - 2019/01 “Pd-catalyzed ring opening of bicyclic aziridine prepared by flow assisted photochemical transformation of pyridinium salt”,
Orientador
 Project III, (Licenciatura/Bacharelato)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2018/09 - 2018/12 Synthesis of bicyclic aziridines as intermediates for the synthesis of compounds with potential anticarcinogenic activity
Orientador
 Drug’s Synthesis laboratory classes (3rdyear students of PharmaceuticalSciences) (Licenciatura/Bacharelato)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2018/03 - 2018/12 “Synthesis of carbocycles from pyridinium salts”
Orientador
Universidade de Lisboa Faculdade de Farmácia, Portugal
2018/06/01 - 2018/07/31 “Pd-catalyzed ring-opening reaction of bicyclic aziridines”
Orientador
 Master Student from Sorbonne Université (Paris) (Mestrado)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2018/02/05 - 2018/07/31 “Synthesis of bicyclic aziridines by photochemical transformation of pyridinium sats”
Orientador
 Project II (Licenciatura/Bacharelato)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2018/04/01 - 2018/04/30 “Valorization of bicyclic vinyl aziridines prepared by photochemical transformation of pyridinium salts, using metal catalysis”
Orientador
 Internship from Sorbonne Université (Paris) (Licenciatura/Bacharelato)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2018/04/01 - 2018/04/30 “Exploring new reaction conditions for aziridine ring opening with isocyanates”
Orientador
 Ph.D. student (one-month Rotatory) (Doutoramento)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2017/09 - 2017/12 “Synthesis of bicyclic aziridines by photochemical transformation of pyridinium sats”
Orientador
 Drug’s Synthesis laboratory classes (Licenciatura/Bacharelato)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2017/05 - 2017/11 “Synthetic and Optimization Procedure of Photochromic Molecules Course”
Orientador
 Ph.D. student from ITQB during the Free Option curricular unit – ITQB Ph.D. Program. (Doutoramento)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2017/07/01 - 2017/07/31 “Synthesis of bicyclic vinyl aziridines by photochemical transformation of pyridinium salts”
Orientador
 Internship from Sorbonne Université (Paris) (Licenciatura/Bacharelato)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2016/09 - 2017/02 “Synthesis of new nitrogen compounds with possible Anti Virus activity”,
Orientador
 Project III (Licenciatura/Bacharelato)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2016/09 - 2016/12 “Synthesis of pyridinium salts as a method of obtaining vinyl bicyclic aziridines”
Orientador
 Drug’s Synthesis laboratory classes (3rd year students of Pharmaceutical Sciences) (Licenciatura/Bacharelato)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2015/09 - 2015/12 "Synthesis of new nitrogen compounds with potential biological activity"
Orientador
Universidade de Lisboa Faculdade de Farmácia, Portugal
2015/09 - 2015/12 “Synthesis of new nitrogen compounds with possible Anti Virus activity”
Orientador
 Drug’s Synthesis laboratory classes (3rd year students of Pharmaceutical Sciences) (Licenciatura/Bacharelato)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2014/07 - 2015/09 "Photochemical synthesis and functional transformations of bicyclic vinyl aziridines"
Orientador
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2014/09 - 2015/01 “Synthesis of quaternary ammonium salts with possible anti malarial activity and acetylcholinesterase inhibitors”,
Orientador
 Project III (3rd-5th year students of Pharmaceutical Sciences): (Licenciatura/Bacharelato)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2013/09 - 2014/02 “Synthesis of quaternary ammonium salts with possible anti malarial activity”
Orientador
 Drug’s Synthesis laboratory classes (3rd year students of Pharmaceutical Sciences) (Licenciatura/Bacharelato)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2012/09 - 2013/02 “New Synthetic methodologies to prepare beta-lactams”
Orientador
 Project III (3rd-5th year students of Pharmaceutical Sciences) (Licenciatura/Bacharelato)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2012/01 - 2012/05 Supervision of ungraduated students of “Synthesis of derivatives of 1,4 cyclohexadienes”
Orientador
 Drug’s Synthesis laboratory classes (3rd year students of Pharmaceutical Sciences) (Licenciatura/Bacharelato)
Universidade de Lisboa Faculdade de Farmácia, Portugal

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação) 		Instituição / Organização
2019/07/04 - Atual Round table to promote internal collaborations for an iMed.ULisboa Call: Young Investigator Projects for Collaborative Cross-disciplinary Studies. Organization: Doctoral Group for Innovation from the Faculty of Pharmacy (2019/07/04)
Mesa-redonda (Coorganizador)
2019/11/14 - 2019/11/15 Lisbon Area Postdoc Metting 2019 - This event is organised by five world renowned institutions from the greater Lisbon area (IMM, ITQB NOVA /IBET, Champalimaud Foundation, FCT-Nova, CEDOC and Faculty of Pharmacy). The aim of the Lisbon Area Postdoc Metting is to promote communication and collaboration amongst PhD holders in a wide variety of fields with a focus on the life sciences (from fundamental physics to applied biomedicine). https://lapd2019.wordpress.com/ (2014/11/14)
Encontro (Coorganizador)
2017/07/16 - 2017/07/17 Member of the Local Organizing Committee of the XXV SPQ National Meeting 2017 (16-19 July 2017) (http://xxvenspq.eventos.chemistry.pt/?setLn=en). Responsible for all the socials events of the conference - Street Food Fest and conference dinner; Registration desk responsible to great and provide information to the participants. (2017/07/16)
Conferência (Membro da Comissão Organizadora)
 Universidade de Lisboa Faculdade de Farmácia Biblioteca, Portugal
2013/09/04 - 2013/09/06 Member of the Local Organizing Committee of the X National Meeting of Organic Chemistry 2013 (4 – 6 September 2013). (2013/09/04)
Conferência (Membro da Comissão Organizadora)

Participação em evento

Descrição da atividade
Tipo de evento 		Nome do evento
Instituição / Organização
2019/03/25 - Atual On-Line personal development course with coaching techniques and NLP
Outro
2018/09/29 - Atual 2nd Meeting of Portuguese Scientists in France, Paris 2018, AGRAFr
Encontro
Association des Diplômés Portugais en France, França
2017/09/30 - Atual 1st Meeting of Portuguese Scientists in France, Paris 2017, AGRAFr. Use science as a means of communication between the scientific community that resides in Portugal and the one that chose France for its projects, defining this meeting as a way of: Introduce a contact point in Portugal to the Portuguese scientific community in France through a guest researcher; Promote dialogue between researchers; Create links between the two communities to hold more meetings; Communicate science in Portuguese.
Encontro
 1st Meeting of Portuguese Scientists in France
Association des Diplômés Portugais en France, França
2020/11/26 - 2020/11/26 Twinning : Institutional networking policy expectations in Horizon 2020 and in the context of the “Widening participation and strengthening the ERA” part of Horizon Europe TWINNING Coordinators Day
European Commission, Bélgica
2019/10/24 - 2019/10/25 COST Action C A15106 (CHAOS), Malta.
2019/09/13 - 2019/09/15 Master Your Life, ALLCAN - Total immersion in the functioning of the human mind that will make you discover why there are results that you have not yet managed to achieve. With NLP and Coaching knowledge resources and tools to teach you how to overcome any fear or fear that is preventing you from reaching your goals.
Oficina (workshop)
2019/07/08 - 2019/07/10 Science and technology submit 2019 in Portugal
Encontro
Fundação para a Ciência e a Tecnologia, Portugal
2019/04/03 - 2019/04/05 COST Action C A15106 (CHAOS), Cyprus
Encontro
2019/01/29 - 2019/01/29 Flash Mob Sciences | International Year of the Periodic Table In Sciences ULisboa, a flash mob was held outside the C8 building, involving students, teachers and other employees, a true Human Periodic Table, with aerial and ground footage, to the music of Los Manitos and Mastiksoul and with choreography by Iza d
Outro
 Flash Mob Sciences | International Year of the Periodic Table
Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal
2018/09/19 - 2018/09/21 COST Action C A15106 (CHAOS), Terragona (Spain)
Encontro
2018/03/22 - 2018/03/23 COST Action C A15106 (CHAOS), Alcala (Spain).
Encontro
2017/05/23 - 2017/05/23 Participation in activities involving the business environment - Siopa, F. was invited by C.M.P. - CIMENTOS MACEIRA E PATAIAS, S.A. to participate in the OPEN DAY of the project FermALG: “Fermentation as inoculum-generating technology for the industrial production of microalgae”, that take place on the factory installations on 23 June 2017 in Pataias, Leiria, Portugal.
Outro

Júri de grau académico

Tema
Tipo de participação 		Nome do candidato (Tipo de grau)
Instituição / Organização
2024/11/25 Light as a powerful tool to create new synthons from aromatic building blocks“. , FCT scholarship (2020.04589.BD).
Orientador
 João André Camilo Oliveira (Doutoramento)
2023/10/20 Functionalization And Biological Evaluation Of New Abietane Diterpenoids
Orientador
 Sabrina Moreira Eyer Cabral (Mestrado)
2023/10/03 Expanding the reactivity of hypervalent iodine reagents”
Arguente principal
 Beatriz Isabel Filipe Dedeira (Mestrado)
2023/07/14 Photochemical Reactions of AMINAL GUANIDINE-BASED MOLECULES: SYNTHESIS AND APPLICATION
Arguente principal
 Rafael Alves Rippel (Doutoramento)
2023/07/07 SYNTHESIS AND APPLICATIONS OF NOVEL BISQUINOLIZIDINE DERIVATIVES FROM BIO RENEWABLE RESOURCES”.
Arguente
 Daniela Filipa Ribeiro Ferreira. (Mestrado)
2023/03/08 Photochemical Reactions of Acylsilanes Towards the Construction of Carbon-Carbon Bonds
Arguente
 João Rafael Campos do Vale (Doutoramento)
2023/03/04 BIOPROSPECÇÃO FITOQUÍMICA, TOXICIDADE E ATIVIDADES ANTIOXIDANTE E ANTICOLINESTERÁSICA DE EXTRATOS DA PARKIA PLATYCEPHALA (BENTH.)
Arguente principal
 Rachel de Moura Nunes Fernandes (Doutoramento)
2022/12/20 2022, December Jury member Master in Pharmaceutical Sciences " C-H Borylation of Furfural Derivatives
Orientador
 Mariana Isabel Crespo Monteiro (Mestrado)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2022/11/27 Jury member Master in Chemistry Bioorganic " Chemical engineered extracts of Portuguese biorenewable resources to the synthesis of diverse natural products hybrids towards new bioactive entities”,
Orientador
 Gonçalo Bernardo Fidalgo Nunes. (Mestrado)
2022/09/30 Jury member Master in Chemistry Bioorganic " N-S Bond Formation mediated by Hypervalent Iodine Reagents”, .
Arguente principal
 Catarina Isabel Pedro Seixas Caldeira (Mestrado)
2022/09/14 Jury member Master in Pharmaceutical Sciences " Development of technology for the neutralization of chemical warfare agents”.
Arguente principal
 Francisco Miguel Hingá Ferreira dos Santos. (Mestrado)
2022/03/17 BIOPROSPECÇÃO FITOQUÍMICA, TOXICIDADE E ATIVIDADES ANTIOXIDANTE E ANTICOLINESTERÁSICA DE EXTRATOS DA PARKIA PLATYCEPHALA (BENTH.)”.
Arguente
 Rachel de Moura Nunes Fernandes (Doutoramento)
2021/02/26 Synthesis of metabolites from the 5-APB and 6-APB drugs of abuse
Arguente principal
 Inês de Sousa Fino (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2019/12 "Pd-Catalyzed Ring Opening of Bicyclic Aziridines Prepared by Photochemical Transformation of Pyridinium Salt Under Continuous Flow"
Vogal
 João André Camilo Oliveira (Mestrado)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2019/11/07 Synthesis of a diterpene of marine origin
Arguente principal
 Henrique Sovela Mourão (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2015/12 “Synthesis of new nitrogen compounds with potential biological activity”
Vogal
 Ana Isabel Baudouin Meirinhos (Mestrado)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2015/09 “Photochemical synthesis and functional transformations of bicyclic vinyl aziridines”
Vogal
 João Rafael Campos du Vale (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Arbitragem científica em revista

Nome da revista (ISSN) Editora
2021/11/18 - Atual Pharmaceuticals
2021/07/26 - Atual Chemico-Biological Interactions ((0009-2797)) Elsevier
2020/12/27 - Atual Molbank (1422-8599) MDPI AG
2020/09/09 - Atual Materials (1996-1944)) MDPI AG
2020/04/20 - Atual Marine Drug (1660-3397) MDPI AG
2019/11/18 - Atual Antibiotics (2079-6382) MDPI AG
2019/06/01 - Atual Journal of Fluorine Chemistry (0022-1139) Elsevier
2019/02/10 - Atual Catalysts (2073-4344) MDPI AG
2018/04/01 - Atual Molecules (1420-3049) MDPI AG
2018/02/06 - Atual Ecotoxicology and Environmental Safety (1090-2414) Elsevier

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2020/09/01 - Atual Teacher of practical classes of Organic Chemistry I (laboratory classes) for second year students of Integrated Master in Pharmaceutical Sciences at Faculty of Pharmacy of the University of Lisbon – 3 hours/week 1st semester (September – January 2020/2021, 2021/2022, 2022/2023 and 2024/2025). (Curso de mestrado (conclusão do curso de especialização))
2019/05/24 - 2019/05/24 Batch versus Flow Photochemistry for the synthesis of bicyclic-aziridines from pyridinium salts: A Comparison of Productivity and Yield (Mestrado integrado) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2014 - 2018 Teacher of practical classes of Organic Chemistry I (laboratory classes) for first year students of Integrated Master in Pharmaceutical Sciences at Faculty of Pharmacy of the University of Lisbon – 3 hours/week 2nd semester (February – July 2014/2015, 2015/2016 and 2017/2018). (Mestrado integrado) Universidade de Lisboa Faculdade de Farmácia, Portugal
2008 - 2010 Teacher of practical classes of Theory of Chemical Bonding for first year class of Chemistry and Biochemistry courses at Faculty of Science and Technology, New University of Lisbon, Portugal - 3 hours/week, 1st semester (September to February 2008/2009 and 2009/2010). (Mestrado integrado) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2007 - 2008 Teacher of practical classes of Chemistry I for first year class of Engineering courses, at Faculty of Science and Technology, New University of Lisbon, Portugal - 3 hours/week; 1st semester -2007/2008. (Mestrado integrado) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Membro de associação

Nome da associação Tipo de participação
2021/01/01 - Atual Straightening training, research and innovation capacities in the valorization of bio-renewable resource (9551996 - Biomass4Synthons), EU, Programme Call: H2020-WIDESPREAD-2018-2020, 900 k€, Coordinator Team, Steering Committee
2019/06/21 - Atual Co-founder of Doctoral Group for Innovation at the Faculty of Pharmacy, University of Lisbon Co-founder

Outro júri / avaliação

Descrição da atividade Instituição / Organização
2020/01/01 - Atual Jury member for the attribution of 10 research grants and 1 junior researcher contract
2016/02/01 - Atual Ana Maria Teles de Carvalho Silva, “a- and ß-Glucosidase Inhibitors – Synthesis and Activity”, (Project III- February 2016). Universidade de Lisboa Faculdade de Farmácia, Portugal
2014/11/01 - Atual Joana Isabel Rosado Lourenço, “Synthesis of new furan derivatives with potential anti-proliferative activity in vitro for lung tumor cells” (Project III- November 2014). Universidade de Lisboa Faculdade de Farmácia, Portugal

Tutoria

Tópico Nome do aluno
2019/04 - Atual Total Synthesis of Agelastatin A, starting from the bicyclic aziridines prepared by photochemical transformation of pyridinium salts João Rafael Campus du Vale (Ph.D. Student)
2019/01 - Atual Design and synthesis of new royleanone derivatives for colon cancer therapy based on PKC-d modulation Vera M. S. Isca (Ph.D. Student)
2019/02 - 2019/06 Total Synthesis of Agelastatin A Milene Andreia Gamito Fortunato (MSc)
Distinções

Prémio

2018 Distinguished Flask Presentation “Imine Furfurals for Ruthenium-Catalyzed Direct C3-H Arylations and Alkenylations” Siopa, F.(speaker); Cladera, V-A. R.; Afonso, C. A. M.; Oble, J.; Poli, G

Outra distinção

2017 TRAMECH IX Best Poster Prize, at the 9th Trans Mediterranean Colloquium on Heterocyclic Chemistry, Fez (Morocco).
2007 Award Câmara Pestana