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First degree in Biochemistry (1992) and MSc in Biomedical Engineering (1996) from the University of Coimbra, Portugal. PhD work under Prof. Terry Jones' supervision at the MRC - Cyclotron Unit, Hammersmith Hospital in London, UK (2002). From 2000 to 2009, helped to design and supervised the construction of the Institute for Nuclear Sciences Applied to Health (ICNAS) a leading facility in Portugal for Nuclear Imaging based at the University of Coimbra. He is the current Director of the Institute and the head of the Radiochemistry Laboratory (RCL). ICNAS has extensive expertise in the development of radiopharmaceuticals for Oncology, Cardiology and Neuroscience and is fully equipped for clinical imaging (2 PET/CT and a 3T MR) as well as pre-clinical studies (including an in-house developed world leading high-resolution small animal PET with 0.3 mm resolution, a 9.4T micro-MRI, an optical imaging system and a photoacoustic tomography device). The RCL hosts 2 cyclotrons (IBA cyclone 18/9 and the first IBA Kiube variable energy, installed in 2019) and is fully licensed as a GMP manufacturing site, currently producing more than 40 different tracers based on 11C, 13N, 18F, 68Ga, 61Cu, 64Cu and 89Zr. The facility is the main supplier of PET radiopharmaceuticals for Portugal, through its subsidiary (ICNAS-Pharma, a company fully owned by the University) that currently has 7 products in the market (FDG, FCH, NaF, F-DOPA, 68Ga-DOTANOC, 68Ga-PSMA-11 and 68GaCl3). Antero's research interests include development of targeted probes for molecular imaging, PET, SPECT, radiopharmaceutical development, PET Radiopharmacy and Quality Control, pre-clinical imaging and clinical trials. The Institute is currently participating in more than 30 clinical trials, including industrial and investigator driven clinical trials. Regarding technology transfer, Antero promoted the start of 3 spin-off companies from the University of Coimbra, one of them specializes in supplying target solutions for radiometal production. He is a member of the European Pharmacopoeia Group 14 and an Expert in several Technical Committees and Field Missions for IAEA (International Atomic Energy Agency). He currently holds patents in Europe, US, Canada and Japan.
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Identificação

Identificação pessoal

Nome completo
Antero José Pena Afonso de Abrunhosa

Nomes de citação

  • Abrunhosa, Antero
  • Abrunhosa, Antero J

Identificadores de autor

Ciência ID
2E1B-49C3-207D
ORCID iD
0000-0002-4145-854X

Domínios de atuação

  • Ciências Médicas e da Saúde - Medicina Clínica - Radiologia, Medicina Nuclear e Imagens Médicas

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Formação
Grau Classificação
2025/06/30
Concluído
 Ciências Biomédicas (Título de Agregado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2002
Concluído
 Biomedical Sciences (Doutoramento)
Universidade de Coimbra Faculdade de Medicina, Portugal
 Distinction and praise
1996
Concluído
 Biomedical Engineering (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
 Very Good
1992
Concluído
 Biochemistry (Licenciatura)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
 Good
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento		 Empregador
2009/09/01 - Atual Investigador (Investigação) Universidade de Coimbra Instituto de Ciências Nucleares Aplicadas à Saúde, Portugal
2015 - 2019 Investigador (Investigação) CNC.IBILI, Portugal

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento		 Empregador
2017 - 2019 Professor Associado (Docente Universitário) Universidade de Coimbra, Portugal
2013 - 2015 Professor Coordenador (Docente Ensino Superior Politécnico) Escola Superior de Saúde Ribeiro Sanches, Portugal
2013 - 2015 Professor Coordenador (Docente Ensino Superior Politécnico) Escola Superior de Saúde Ribeiro Sanches, Portugal
2013 - 2015 Professor Coordenador (Docente Ensino Superior Politécnico) Escola Superior de Saúde Ribeiro Sanches, Portugal

Cargos e Funções

Categoria Profissional
Instituição de acolhimento		 Empregador
2017/11/22 - Atual Director de Unidade Orgânica Universidade de Coimbra Instituto de Ciências Nucleares Aplicadas à Saúde, Portugal
2017 - 2019 Conselho científico/técnico-científico ou orgão correspondente Universidade de Coimbra, Portugal
2017 - 2019 Coordenação ou direção de centro de investigação, departamento ou equivalente Universidade de Coimbra, Portugal
2017 - 2019 Diretor ou presidente da unidade orgânica Universidade de Coimbra, Portugal
2017 - 2018 Conselho científico/técnico-científico ou orgão correspondente Universidade de Coimbra, Portugal
2017 - 2018 Coordenação ou direção de centro de investigação, departamento ou equivalente Universidade de Coimbra, Portugal
2017 - 2018 Diretor ou presidente da unidade orgânica Universidade de Coimbra, Portugal
2017 - 2018 Conselho científico/técnico-científico ou orgão correspondente Universidade de Coimbra, Portugal
2017 - 2018 Coordenação ou direção de centro de investigação, departamento ou equivalente Universidade de Coimbra, Portugal
2017 - 2018 Diretor ou presidente da unidade orgânica Universidade de Coimbra, Portugal
2013 - 2015 Conselho científico/técnico-científico ou orgão correspondente Escola Superior de Saúde Ribeiro Sanches, Portugal
2013 - 2015 Conselho científico/técnico-científico ou orgão correspondente Escola Superior de Saúde Ribeiro Sanches, Portugal
2013 - 2015 Conselho científico/técnico-científico ou orgão correspondente Escola Superior de Saúde Ribeiro Sanches, Portugal

Outros

Categoria Profissional
Instituição de acolhimento		 Empregador
1999/10/01 - Atual Invited Professor Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
1995/10/01 - 1999/09/30 PhD student MRC Clinical Sciences Centre, Reino Unido
1992/10/01 - 1995/09/30 MSc student Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
1991/10/01 - 1992/09/30 First degree, Final year placement Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
Projetos

Bolsa

Designação Financiadores
2019/07 - Atual Development of New PET Probes for the Neuropeptide Y System
PD/BDE/150334/2019
Universidade de Coimbra Faculdade de Farmácia, Portugal
Em curso
2013 - Atual From molecules to man: novel diagnostic imaging tools in neurological and psychiatric disorders
PEst-C/SAU/UI3282/2013 CENTRO-07-ST24-FEDER-00205
 QREN
2012 - Atual Molecular and Nano Tools for Cancer Theranostics
EXCL/QEQ-MED/0233/2012
 Fundação para a Ciência e a Tecnologia
2008 - Atual A novel technology for single-bed whole-body human molecular imaging with higher sensitivity and resolution
PTDC/SAU-BEB/104630/2008
 Fundação para a Ciência e a Tecnologia, I.P.
2008 - Atual Radiolabeled Benzazole Derivatives for In Vivo Imaging of Amyloid Aggregation
PTDC/QUI-QUI/102049/2008
 Fundação para a Ciência e a Tecnologia
2006 - Atual Targeted Nanoconstructs for Multimodal Medical Molecular Imaging
PTDC/QUI/70063/2006
 Fundação para a Ciência e a Tecnologia
2016/07 - 2018/06 Quantification in PET: construction of a distributed non-invasive system for measuring the arterial input function
PTDC/BBB-BMD/5378/2014
 Universidade de Coimbra
1995/10/01 - 1999/09/30 UTILIZAÇÃO DO COMPUTADOR NO PROJECTO DE MOLÉCULAS COM INTERESSE PARA UTILIZAÇÃO NO PET E NA SUA SÍNTESE AUTOMÁTICA
PRAXIS XXI/BD/4563/94
Medical Research Council, Reino Unido

Universidade de Coimbra Faculdade de Medicina, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
1995/10/01 - 1999/09/30 UTILIZAÇÃO DO COMPUTADOR NO PROJECTO DE MOLÉCULAS COM INTERESSE PARA UTILIZAÇÃO NO PET E NA SUA SÍNTESE AUTOMÁTICA
PRAXIS XXI/BD/4563/94
Universidade de Coimbra Faculdade de Medicina, Portugal

Medical Research Council, Reino Unido
 Fundação para a Ciência e a Tecnologia
Concluído

Projeto

Designação Financiadores
2021 - Atual New imaging biomarkers in the assessment of chronic total coronary occlusion (Novos biomarcadores de imagem na avaliação das oclusões coronárias crónicas totais)
BioImage2CTO - 39698
 Agência Nacional de Inovação SA
2025/01/01 - 2027/12/31 A Nanobody-based theranostic tool for HER2-positive breast cancer brain metastasis.
2023.18439.ICDT
10.54499/2023.18439.ICDT
Universidade de Coimbra, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2023/03/12 - 2026/03/11 Interação calcitonina-receptor promovida por nanopartículas guiadas por péptidos como uma nova abordagem para tratamento de glioblastoma
10.54499/2022.06174.PTDC
Universidade de Coimbra, Portugal

Universidade de Coimbra Instituto de Ciências Nucleares Aplicadas à Saúde, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2023/03/01 - 2026/02/28 The Neurovascular Coupling as a biomarker and a target for cognitive enhancement in aging and vascular dementia through an innovative dietary nitrate-driven nitric oxide redox cycle: a translational study
2022.05454.PTDC
10.54499/2022.05454.PTDC
Universidade de Coimbra, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2021/01/01 - 2025/12/31 Intelligent Systems Associate Laboratory
LA/P/0104/2020
Universidade Nova de Lisboa Centro de Tecnologias e Sistemas, Portugal

Universidade de Aveiro Centro de Tecnologia Mecânica e Automação, Portugal

Instituto Politécnico do Porto Centro de Investigação em Sistemas Computacionais Embebidos e de Tempo-Real, Portugal

Universidade do Minho, Portugal

Universidade do Porto Faculdade de Ciências, Portugal

Universidade do Porto Centro de Matemática, Portugal

Instituto Politécnico do Cávado e do Ave, Portugal

Universidade do Porto Laboratório de Inteligência Artificial e Ciência de Computadores, Portugal

Universidade de Aveiro, Portugal

Universidade do Minho Instituto de Polímeros e Compósitos, Portugal

Universidade de Aveiro Instituto de Engenharia Eletrónica e Informática de Aveiro, Portugal

Universidade do Minho Centro ALGORITMI, Portugal

Universidade Nova de Lisboa Unidade de Investigação e Desenvolvimento em Engenharia Mecânica e Industrial, Portugal

Universidade de Coimbra, Portugal

Instituto Politécnico do Porto Instituto Superior de Engenharia do Porto, Portugal

Universidade de Coimbra Centro de Informatica e Sistemas, Portugal

Instituto Politécnico do Porto Grupo de Investigação em Engenharia e Computação Inteligente para a Inovação e o Desenvolvimento, Portugal

Universidade do Porto Faculdade de Engenharia, Portugal

Universidade NOVA de Lisboa, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2021/03/29 - 2025/03/28 Radiolabeled EXosomes - a nanotheranostic tool for lung micrometastasis in osteosarcoma
PTDC/BTM-SAL/4451/2020
10.54499/PTDC/BTM-SAL/4451/2020
Universidade de Coimbra, Portugal

Universidade de Coimbra Instituto de Investigação Clínica e Biomédica de Coimbra, Portugal

Centro Hospitalar e Universitário de Coimbra EPE, Portugal

Universidade de Coimbra Faculdade de Medicina, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2021/06 - 2023/08 LABEL - Radio-marcação de vesiculas extracelulares para aplicações em diagnóstico e terapêuticas
POCI-01-0247-FEDER-049268
 PT2020 (FEDER)
2019/09 - 2021/09 HiRezBrainPET: High Resolution Positron Emission Tomography for Brain Imaging
POCI-01-0247-FEDER-039808
 PT2020 (FEDER)
2018/07/26 - 2021/07/25 Melhoria cognitiva no cérebro idoso e demência vascular em humanos através da funcionalização do acoplamento neurovascular: uma estratégia mecanística molecular promovida por nitrito e ácido ascórbico da dieta
PTDC/MED-NEU/29099/2017
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Centro Hospitalar e Universitário de Coimbra EPE, Portugal

Universidade de Coimbra, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2020/10 - 2020/12 VentiLab 4 COVID-19 .: Laboratório especializado no teste e certificação de equipamentos médicos respiratórios no âmbito da COVID-19
POCI-01-02B7-FEDER-069499
 PT2020 (FEDER)
2017/02 - 2020/01 Synaptic networks and Personalized Medicine Approaches to Understand Neurobehavioural Diseases Across the Lifespan
SAICTPAC/0010/2015
 Universidade de Coimbra
2019/01/01 - 2019/12/31 CNC. IBILI
UID/NEU/04539/2019
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Universidade de Coimbra, Portugal

Universidade de Coimbra Instituto de Ciências Nucleares Aplicadas à Saúde, Portugal

Universidade de Coimbra Instituto de Investigação Clínica e Biomédica de Coimbra, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2017/07 - 2019/07 DOPAPET-DCP: Development of an innovative microwave assisted synthesis process for F-DOPA
POCI-01-0247-FEDER-023747
 PT2020 (FEDER)
2013/06/01 - 2015/09/30 O metilfenidato e as alterações na barreira hemato-encefálica numa situação fisiológica e na perturbação de hiperatividade com défice de atenção
PTDC/NEU-OSD/0312/2012
Universidade de Coimbra, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2011/01/01 - 2012/12/31 Projecto Estratégico - UI 3282 - 2011-2012
PEst-C/SAU/UI3282/2011
Universidade de Coimbra, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2005/01/01 - 2008/06/30 Tomógrafo PET humano de alta sensibilidade e baixo custo: testes de viabilidade
POCI/SAU-OBS/61642/2004
Laboratório de Instrumentação e Física Experimental de Partículas Coimbra, Portugal

Laboratório de Instrumentação e Física Experimental de Partículas Coimbra, Portugal

Universidade de Coimbra Faculdade de Medicina, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
1995/10/01 - 1999/09/30 UTILIZAÇÃO DO COMPUTADOR NO PROJECTO DE MOLÉCULAS COM INTERESSE PARA UTILIZAÇÃO NO PET E NA SUA SÍNTESE AUTOMÁTICA
PRAXIS XXI/BD/4563/94
Universidade de Coimbra, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
Produções

Publicações

Artigo em conferência
  1. Lapo Pais, Marta; Jorge, Lília; Martins, Ricardo; Canário, Nádia; Xavier, Carolina; Abrunhosa, Antero; Santana, Isabel; Bernardes, Rui; Castelo-Branco, Miguel. "Texture Quantification Parameters for Alzheimer's disease diagnosis measured by 11C- (R)- PK11195 PET images". Trabalho apresentado em European Journal of Nuclear Medicine and Molecular Imaging - EANM2021 - Annual Congress of the European Association of Nuclear Medicine, Online, 2021.
    Publicado
  2. Pereira, C.; Abrunhosa, A.; Cruz, A.; Ferreira, N.; Moreira, A.; Oliveira, F.; Patricio, M.; Caramelo, F.. "Distributed non-invasive system for measuring the arterial input function in PET". 2018.
    10.1109/NSSMIC.2017.8532753
  3. Alves, F.; Alves, V.H.; Neves, A.C.B.; Do Carmo, S.J.C.; Nactergal, B.; Hellas, V.; Kral, E.; Gonçalves-Gameiro, C.; Abrunhosa, A.J.. "Cyclotron production of Ga-68 for human use from liquid targets: From theory to practice". 2017.
    10.1063/1.4983532
  4. Cristina Serra; Angela Neves; Antero J. Abrunhosa; Luis F. Metello. "Optimization and validation of [<sup>13</sup>N]-NH<inf>3</inf> production for clinical studies of positron emission tomography in the evaluation of myocardial perfusion". 2015.
    10.1109/enbeng.2015.7088887
  5. Serra, C.; Neves, A.; Abrunhosa, A.J.; Metello, L.F.. "Optimization and validation of [<sup>13</sup>N]-NH<inf>3</inf> production for clinical studies of positron emission tomography in the evaluation of myocardial perfusion". 2015.
    10.1109/ENBENG.2015.7088887
  6. Serra, Cristina; Neves, Angela; Abrunhosa, Antero J.; Metello, Luis F.. "Optimization and validation of [13N]-NH3 production for clinical studies of positron emission tomography in the evaluation of myocardial perfusion". 2015.
    10.1109/ENBENG.2015.7088887
  7. Martins, P.; Blanco, A.; arques, Crespo P.; Marques, M. F. F.; Marques, R. F.; Gordo, P. M.; Kajetanowicz, M.; et al. "AN ULTRA-HIGH RESOLUTION PRECLINICAL POSITRON EMISSION TOMOGRAPHY SCANNER". 2015.
    10.1109/ENBENG.2015.7088828
  8. Serra, Cristina; Neves, Angela; Abrunhosa, Antero J.; Metello, Luis F.. "Optimization and Validation of [N-13]-NH3 Production for Clinical Studies of Positron Emission Tomography in the Evaluation of Myocardial Perfusion". 2015.
  9. Vitor H. Alves; Antero J. Abrunhosa; Miguel Castelo-Branco. "Optimisation of synthesis, purification and reformulation of (R)-[N-Methyl-11C]PK11195 for in vivo PET imaging studies". 2013.
    10.1109/enbeng.2013.6518428
  10. Alves, V.H.; Abrunhosa, A.J.; Castelo-Branco, M.. "Optimisation of synthesis, purification and reformulation of (R)-[N-Methyl-11C]PK11195 for in vivo PET imaging studies". 2013.
    10.1109/ENBENG.2013.6518428
  11. Faustino, R.; Rio, J.; Ferreira, C.; Marques, J.P.; Abrunhosa, A.J.; Ferreira, N.C.; Castelo-Branco, M.; et al. "Image analysis in radiology and nuclear medicine". 2013.
    10.1109/ENBENG.2013.6518385
  12. Faustino, R.; Rio, J.; Ferreira, C.; Marques, J. P.; Abrunhosa, A. J.; Ferreira, N. C.; Castelo-Branco, M.; et al. "Image Analysis in Radiology and Nuclear Medicine Automated Analysis of Morfology and Funtion of the Human Brain". 2013.
  13. Alves, Vitor H.; Abrunhosa, Antero J.; Castelo-Branco, Miguel. "Optimisation of Synthesis, Purification and Reformulation of (R)-[N-Methyl-C-11]PKll195 for In Vivo PET Imaging Studies". 2013.
  14. R. Faustino; A. J. Abrunhosa; M. Castelo-Branco. "Neuronal and developmental effects of high magnetic fields in the development of an intact living organism: Ceanorhabditis elegans". 2012.
    10.1109/enbeng.2012.6331363
  15. Faustino, R.; Abrunhosa, A.J.; Castelo-Branco, M.. "Neuronal and developmental effects of high magnetic fields in the development of an intact living organism: Ceanorhabditis elegans". 2012.
    10.1109/ENBENG.2012.6331363
  16. Clemente, G.; Alves, V.; Abrunhosa, A.J.. "Synthesis optimization of pittsburgh compound B by the captive solvent method". 2012.
    10.1109/ENBENG.2012.6331358
  17. Neves, S.C.; Oliveira, V.E.; Do Carmo, A.; Abrunhosa, A.J.; Botelho, M.F.; Gomes, C.M.. "Elucidation of the drug resistance mechanisms of osteosarcoma cancer stem cells with PET tracers". 2011.
    10.1109/ENBENG.2011.6026060
  18. Gomes, C.M.; Welling, M.M.; Que, I.; Henriquez, N.; Van Der Pluijm, G.; Abrunhosa, A.J.; Botelho, M.F.; et al. "Imaging multidrug resistance in osteosarcoma: A pre-clinical approach using an orthotopic animal model". 2009.
    10.1007/978-3-642-03879-2-219
Artigo em revista
  1. Lília Jorge; Nádia Canário; Ricardo Martins; Antero Abrunhosa; Isabel Santana; Miguel Castelo-Branco. "The relation between neuroinflammation, amyloid-ß load, grey matter loss and brain activity in visual object recognition regions in Alzheimer's Disease". NeuroImage: Reports (2026): https://doi.org/10.1016/j.ynirp.2025.100305.
    10.1016/j.ynirp.2025.100305
  2. Patrícia Marques-Alves; Maria João Ferreira; Rodolfo Silva; João Borges-Rosa; Andreia Gomes; Antero Abrunhosa; Miguel Castelo-Branco; Wael Jaber; Lino Gonçalves. "2-[18F]FDG PET/CT identifies metabolic activity linked to myocardial deformation in hypertrophic cardiomyopathy". Meta-Radiology (2025): https://doi.org/10.1016/j.metrad.2025.100173.
    10.1016/j.metrad.2025.100173
  3. Diana Rodrigues; Alexandra I. Fonseca; João N. Moreira; Célia Gomes; Antero Abrunhosa. "Molecular targets and the emerging role of copper radionuclides in prostate cancer theranostics". EJNMMI Research (2025): https://doi.org/10.1186/s13550-025-01325-4.
    10.1186/s13550-025-01325-4
  4. Marta Lapo Pais; Joana Crisóstomo; Antero Abrunhosa; Miguel Castelo-Branco. "PET/fMRI demonstrates that bariatric surgery may reverse striatal dopaminergic dysfunction in women with obesity". Communications Medicine (2025): https://doi.org/10.1038/s43856-025-01079-z.
    10.1038/s43856-025-01079-z
  5. Mariana Lapo Pais; José Sereno; Vanessa A. Tomé; Carla Fonseca; Camila Seco; Inês Ribeiro; João Martins; et al. "Sex-specific cortical networks drive social behavior differences in an autism spectrum disorder model". Translational Psychiatry (2025): https://doi.org/10.1038/s41398-025-03464-7.
    10.1038/s41398-025-03464-7
  6. Ana Rita C Teixeira; Joana Antunes; Catarina I G Pinto; Maria Paula Cabral Campello; Pedro Santos; Célia M Gomes; Antero J Abrunhosa; et al. "GRPR-targeted gold nanoparticles as selective radiotherapy enhancers in glioblastoma". Physics in Medicine & Biology (2025): https://doi.org/10.1088/1361-6560/ade222.
    10.1088/1361-6560/ade222
  7. A. I. Fonseca; J. Sereno; S. Almeida; H. Ferreira; I. Hrynchak; A. Falcão; F. Alves; C. Gomes; A. J. Abrunhosa. "Unveiling the potential of copper-61 vs. gallium-68 for SSTR PET imaging". European Journal of Nuclear Medicine and Molecular Imaging (2025): https://doi.org/10.1007/s00259-025-07116-2.
    10.1007/s00259-025-07116-2
  8. Fabiana M. Ribeiro; Pedro M. C. C. Encarnação; Ana L. M. Silva; Pedro M. M. Correia; Afonso X. Pinto; Regina G. Oliveira; José Sereno; et al. "First performance evaluation of easyPET.3D, a high-resolution and cost-effective benchtop preclinical PET scanner". EJNMMI Physics (2025): https://doi.org/10.1186/s40658-025-00757-0.
    10.1186/s40658-025-00757-0
  9. Diana Rodrigues; Alexandra I. Fonseca; Sérgio do Carmo; José Sereno; Ivanna Hrynchak; João N. Moreira; Célia Gomes; Antero Abrunhosa. "Is Copper-61 the New Gallium-68? Automation and Preclinical Proof-of-Concept of 61Cu-Based Radiopharmaceuticals for Prostate Cancer Imaging". Pharmaceuticals (2025): https://doi.org/10.3390/ph18040469.
    10.3390/ph18040469
  10. Ferreira M.; Matias F.; Abrunhosa A.; Martins R.; Castelo-Branco M.; Massimo Grilli. "Evidence for Neuroplasticity in the Human Brain in Health and Disease: A Systematic Review Focusing on Molecular Imaging Using PET". Neural Plasticity (2025): https://doi.org/10.1155/np/9423232.
    10.1155/np/9423232
  11. Sergio J. C. do Carmo; Ângela C. B. Neves; Eric Kral; Jean-Michel Geets; Benoit Nactergal; Antero J. Abrunhosa; Francisco Alves. "Improved Production of Novel Radioisotopes with Custom Energy Cyclone® Kiube". Instruments (2024): https://doi.org/10.3390/instruments8030038.
    10.3390/instruments8030038
  12. Inês C. F. Fonseca; Mariana Lapo Pais; Fábio M. S. Rodrigues; José Sereno; Miguel Castelo-Branco; Cláudia Cavadas; Mariette M. Pereira; Antero J. Abrunhosa. "Improved Chemical and Radiochemical Synthesis of Neuropeptide Y Y2 Receptor Antagonist N-Methyl-JNJ-31020028 and Preclinical Positron Emission Tomography Studies". Pharmaceuticals (2024): https://doi.org/10.3390/ph17040474.
    10.3390/ph17040474
  13. Diana Cocioaba; Alexandra I. Fonseca; Radu Leonte; Ivanna Hrynchak; Roxana Tudoroiu-Cornoiu; Sergio J. C. do Carmo; Bogdan Burghelea; et al. "Neurotensin (8-13) and Neuromedin N Neuropeptides Radiolabelling with Copper-64 Produced on Solid or Liquid Targets". Molecules (2024): https://www.mdpi.com/1420-3049/29/6/1390.
    10.3390/molecules29061390
  14. Alexandra I. Fonseca; Sérgio J. C. Do Carmo; Ivanna Hrynchak; Vítor Alves; Francisco Alves; Antero J. Abrunhosa. "Purification of Copper Radioisotopes for Medical Applications: Chromatographic Methods and Challenges". Separation & Purification Reviews (2023): https://doi.org/10.1080/15422119.2023.2270469.
    10.1080/15422119.2023.2270469
  15. Alexandra I. Fonseca; Vítor H. Alves; Ivanna Hrynchak; Francisco Alves; Antero J. Abrunhosa. "Fully Automated Production of [68Ga]GaFAPI-46 with Gallium-68 from Cyclotron Using Liquid Targets". International Journal of Molecular Sciences (2023): https://doi.org/10.3390/ijms242015101.
    10.3390/ijms242015101
  16. Banerjee, Arnab; Lino, Miguel; Jesus, Carlos; Ribeiro, Quélia; Abrunhosa, Antero; Ferreira, Lino. Autor correspondente: Ferreira, Lino. "Imaging platforms to dissect the in vivo communication, biodistribution and controlled release of extracellular vesicles". Journal of Controlled Release 360 (2023): 549-563. http://dx.doi.org/10.1016/j.jconrel.2023.06.039.
    Publicado • 10.1016/j.jconrel.2023.06.039
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  82. Domingues, C.; Oliveira-Santos, M.; Castelo-Branco, M.; Silva, R.; Gomes, A.; Chichorro, N.; Abrunhosa, A.; et al. "Cardiovascular risk, aortic valve microcalcification and vascular microcalcification: is there a link?". European Heart Journal (2019): https://publons.com/wos-op/publon/33346986/.
  83. Banerjee, Arnab; Rondao, Tiago; Sereno, Jose; Alves, Vitor; Lino, Miguel; Ribeiro, Andreia; Abrunhosa, Antero; Ferreira, Lino. "PET imaging and in vivo bio-distribution of small extracellular vesicles". European Journal of Clinical Investigation (2019): https://publons.com/wos-op/publon/53879095/.
  84. Niculae, D.; Chilug, L. E.; Serban, R. M.; Abrunhosa, A. J.; Leonte, R. A.; Turcu, R.; Nan, A.; Lavric, V.. "Activated Gold Nanoparticles Conjugated with 68Ga-DOTA-PEG(4)-BBN(7-14) for Targeting Tumours Expressing GRP Receptors". European Journal of Nuclear Medicine and Molecular Imaging (2019): https://publons.com/wos-op/publon/27831977/.
  85. Bousquet, J.; Illario, M.; Farrell, J.; Batey, N.; Carriazo, A. M.; Malva, J.; Hajjam, J.; et al. "THE REFERENCE SITE COLLABORATIVE NETWORK OF THE EUROPEAN INNOVATION PARTNERSHIP ON ACTIVE AND HEALTHY AGEING". Translational Medicine @ UniSa (2019): https://publons.com/wos-op/publon/21269344/.
  86. Banerjee, Arnab; Alves, Vitor; Rondão, Tiago; Sereno, José; Neves, Ângela; Lino, Miguel; Ribeiro, Andreia; Abrunhosa, Antero; Ferreira, Lino. "A positron-emission tomography (PET)/magnetic resonance imaging (MRI) platform to track in vivo small extracellular vesicles". (2019): https://hdl.handle.net/10316/87318.
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  87. Carlos F. D. Rodrigues; Eurico Serrano; Maria I. Patrício; Mariana M. Val; Patrícia Albuquerque; João Fonseca; Célia M. F. Gomes; et al. "Stroma-derived IL-6, G-CSF and Activin-A mediated dedifferentiation of lung carcinoma cells into cancer stem cells". Scientific Reports 8 1 (2018): https://doi.org/10.1038/s41598-018-29947-w.
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  88. Joana F Guerreiro; Vítor Alves; Antero Abrunhosa; António Paulo; Octávia Monteiro Gil; F Mendes. "Radiobiological Characterization of <sup>64</sup>CuCl<sub>2</sub> as a Simple Tool for Prostate Cancer Theranostics". Molecules (2018): http://www.mdpi.com/1420-3049/23/11/2944.
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  89. Vítor Alves; Sergio JC do Carmo; Francisco José Cerqueira Alves; Antero Abrunhosa. "Automated Purification of Radiometals Produced by Liquid Targets". Instruments (2018): http://www.mdpi.com/2410-390X/2/3/17.
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  90. Daniela I. Paiva-Oliveira; Sara R. Martins-Neves; Antero J. Abrunhosa; Carlos Fontes-Ribeiro; Célia M. F. Gomes. "Therapeutic potential of the metabolic modulator Metformin on osteosarcoma cancer stem-like cells". Cancer Chemotherapy and Pharmacology (2018): https://doi.org/10.1007/s00280-017-3467-6.
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  91. Oliveira, F.; Leuzy, A.; Castelhano, J.; Chiotis, K.; Hasselbalch, S.G.; Rinne, J.; Mendonça, A.; et al. "Data driven diagnostic classification in Alzheimer's disease based on different reference regions for normalization of PiB-PET images and correlation with CSF concentrations of Aß species". NeuroImage: Clinical 20 (2018): 603-610. http://www.scopus.com/inward/record.url?eid=2-s2.0-85052649302&partnerID=MN8TOARS.
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  92. Oliveira, F.P.M.; Moreira, A.P.; De Mendonça, A.; Verdelho, A.; Xavier, C.; Barroca, D.; Rio, J.; et al. "Can 11 C-PiB-PET relative delivery R 1 or 11 C-PiB-PET perfusion replace 18 F-FDG-PET in the assessment of brain neurodegeneration?". Journal of Alzheimer's Disease 65 1 (2018): 89-97. http://www.scopus.com/inward/record.url?eid=2-s2.0-85051843086&partnerID=MN8TOARS.
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  93. Oliveira, Francisco P.M.; Moreira, Ana Paula; De Mendonça, Alexandre; Verdelho, Ana; Xavier, Carolina; Barroca, Dalila; Rio, Joana; et al. "Can 11C-PiB-PET relative delivery R1 or 11C-PiB-PET perfusion replace 18F-FDG-PET in the assessment of brain neurodegeneration?". (2018): http://hdl.handle.net/10451/36409.
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  94. Gois, L.; Ferreira, N.; Abrunhosa, A.; Moreira, A.; Oliveira, F.; Patricio, M.; Caramelo, F.. "qPET: a system for assessing the arterial input function for PET quantification". European Journal of Nuclear Medicine and Molecular Imaging (2018): https://publons.com/wos-op/publon/29668912/.
  95. Bertrand, S.; Geets, J.; Kral, E.; Gameiro, C.; Nactergal, B.; Devillet, F.; Alves, F.; et al. "Optimized non-conventional radioisotopes production with industrial mid-energy cyclotron". European Journal of Nuclear Medicine and Molecular Imaging (2018): https://publons.com/wos-op/publon/53879096/.
  96. Alves, Vítor H. P.; Carmo, Sérgio do; Alves, Francisco; Abrunhosa, Antero. "Automated Purification of Radiometals Produced by Liquid Targets". (2018): https://hdl.handle.net/10316/107677.
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  97. Abrunhosa, Antero. "Deconstructing cancer stem cells: IL-6, G-CSF and Activin-A as mediators of stroma-orchestrated epithelial cells’ dedifferentiation". Cancer Research 77 13 Supplem (2017): 1915-1915. https://doi.org/10.1158%2F1538-7445.am2017-1915.
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  98. Abrunhosa, Antero. "Production of copper-64 and gallium-68 with a medical cyclotron using liquid targets". Modern Physics Letters A (2017):
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  99. Oliveira-Santos M; Castelo-Branco M; Silva R; Gomes A; Chichorro N; Abrunhosa A; Donato P; et al. "Atherosclerotic plaque metabolism in high cardiovascular risk subjects - A subclinical atherosclerosis imaging study with 18F-NaF PET-CT.". (2017): http://europepmc.org/abstract/med/28349887.
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  100. Palma E; Mendes F; Morais GR; Rodrigues I; Santos IC; Campello MP; Raposinho P; et al. "Biophysical characterization and antineoplastic activity of new bis(thiosemicarbazonato) Cu(II) complexes.". (2017): http://europepmc.org/abstract/med/27907865.
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  101. Ferreira MJ; Oliveira-Santos M; Silva R; Gomes A; Ferreira N; Abrunhosa A; Lima J; et al. "Assessment of atherosclerotic plaque calcification using F18-NaF PET-CT.". (2017): http://europepmc.org/abstract/med/28070735.
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  102. Do Carmo, S.J.C.; Alves, V.H.P.; Alves, F.; Abrunhosa, A.J.. "Fast and cost-effective cyclotron production of<sup>61</sup>Cu using a<sup>nat</sup>Zn liquid target: An opportunity for radiopharmaceutical production and R&amp;D". Dalton Transactions 46 42 (2017): 14556-14560. http://www.scopus.com/inward/record.url?eid=2-s2.0-85032646302&partnerID=MN8TOARS.
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  103. Alves, F.; Alves, V.H.P.; Do Carmo, S.J.C.; Neves, A.C.B.; Silva, M.; Abrunhosa, A.J.. "Production of copper-64 and gallium-68 with a medical cyclotron using liquid targets". Modern Physics Letters A 32 17 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85019686668&partnerID=MN8TOARS.
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  104. Gonçalves, J.; Violante, I.R.; Sereno, J.; Leitão, R.A.; Cai, Y.; Abrunhosa, A.; Silva, A.P.; Silva, A.J.; Castelo-Branco, M.. "Testing the excitation/inhibition imbalance hypothesis in a mouse model of the autism spectrum disorder: In vivo neurospectroscopy and molecular evidence for regional phenotypes". Molecular Autism 8 1 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85029603049&partnerID=MN8TOARS.
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  105. S. J. C. do Carmo; V. H. P. Alves; F. Alves; A. J. Abrunhosa. "Fast and cost-effective cyclotron production of 61Cu using a natZn liquid target: an opportunity for radiopharmaceutical production and R&D". Dalton Transactions 46 42 (2017): 14556-14560. https://doi.org/10.1039/C7DT01836C.
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  106. Alves, Francisco; Alves, Vitor; Neves, Angela; Abrunhosa, Antero. "GMP Production of Gallium-68 from a Cyclotron Using Liquid Targets: Regulatory Aspects". Journal of Labelled Compounds (2017): https://publons.com/wos-op/publon/53879097/.
  107. Antero J Abrunhosa; Vitor Hugo Alves; Angela Neves; Carmo Sergio JC do; Benoit Nactergal; Vincent Hellas; Erik Kral; Cristiana Gameiro-Paris; Francisco Alves. "Production of 68Ga in a mid-energy cyclotron: the solution is in the target". Endocrine Abstracts (2016): https://doi.org/10.1530%2Fendoabs.47.oc49.
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  108. Violante IR; Patricio M; Bernardino I; Rebola J; Abrunhosa AJ; Ferreira N; Castelo-Branco M. "GABA deficiency in NF1: A multimodal [11C]-flumazenil and spectroscopy study.". (2016): http://europepmc.org/abstract/med/27473134.
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  110. Martins-Neves SR; Paiva-Oliveira DI; Wijers-Koster PM; Abrunhosa AJ; Fontes-Ribeiro C; Bovée JV; Cleton-Jansen AM; Gomes CM. "Chemotherapy induces stemness in osteosarcoma cells through activation of Wnt/ß-catenin signaling.". (2016): http://europepmc.org/abstract/med/26577806.
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  111. Violante, I.R.; Patricio, M.; Bernardino, I.; Rebola, J.; Abrunhosa, A.J.; Ferreira, N.; Castelo-Branco, M.. "GABA deficiency in NF1". Neurology 87 9 (2016): 897-904. http://www.scopus.com/inward/record.url?eid=2-s2.0-84984801008&partnerID=MN8TOARS.
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  112. Silva, R.; Abrunhosa, A.; Figueiredo, A.; Cruz, A.; Xavier, A.; Barroca, D.; Castelo Branco, M.; Pedroso de Lima, J.. "68Ga-PSMA PET/CT in Biochemical Relapsed Prostate Cancer Initial Experience". European Journal of Nuclear Medicine and Molecular Imaging (2016): https://publons.com/wos-op/publon/17779119/.
  113. Nuno P. F. Gonçalves; Ana V. C. Simões; Artur R. Abreu; Antero J. Abrunhosa; Janusz M. Dabrowski; Mariette M. Pereira. "Synthesis and biological distribution study of a new carbon-11 labeled porphyrin for PET imaging. Photochemical and biological characterization of the non-labeled porphyrin". Journal of Porphyrins and Phthalocyanines 19 08 (2015): 946-955. https://doi.org/10.1142%2Fs1088424615500728.
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  114. Goncalves, N.P.F.; Simões, A.V.C.; Abreu, A.R.; Abrunhosa, A.J.; Dabrowski, J.M.; Pereira, M.M.. "Synthesis and biological distribution study of a new carbon-11 labeled porphyrin for PET imaging. Photochemical and biological characterization of the non-labeled porphyrin". Journal of Porphyrins and Phthalocyanines 19 8 (2015): 946-955. http://www.scopus.com/inward/record.url?eid=2-s2.0-84940055201&partnerID=MN8TOARS.
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  115. Goreti Ribeiro Morais; Elisa Palma; Fernanda Marques; Lurdes Gano; Maria Cristina Oliveira; Antero Abrunhosa; Hugo Vicente Miranda; et al. "Synthesis and Biological Evaluation of Novel 2-Aryl Benzimidazoles as Chemotherapeutic Agents". Journal of Heterocyclic Chemistry 54 1 (2015): 255-267. https://doi.org/10.1002%2Fjhet.2575.
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  116. Simões, A.V.C.; Pinto, S.M.A.; Calvete, M.J.F.; Gomes, C.M.F.; Ferreira, N.C.; Castelo-Branco, M.; Llop, J.; Pereira, M.M.; Abrunhosa, A.J.. "Synthesis of a new <sup>18</sup>F labeled porphyrin for potential application in positron emission tomography. in vivo imaging and cellular uptake". RSC Advances 5 120 (2015): 99540-99546. http://www.scopus.com/inward/record.url?eid=2-s2.0-84948415914&partnerID=MN8TOARS.
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  117. Appelberg, R.; Moreira, D.; Barreira-Silva, P.; Borges, M.; Silva, L.; Dinis-Oliveira, R.J.; Resende, M.; et al. "The Warburg effect in mycobacterial granulomas is dependent on the recruitment and activation of macrophages by interferon-¿". Immunology 145 4 (2015): 498-507. http://www.scopus.com/inward/record.url?eid=2-s2.0-84936175105&partnerID=MN8TOARS.
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  118. Alves, V.H.; Prata, M.I.M.; Abrunhosa, A.J.; Castelo-Branco, M.. "GMP production of <sup>68</sup>Ga-labelled DOTA-NOC on IBA Synthera". Journal of Radioanalytical and Nuclear Chemistry 305 2 (2015): 501-506. http://www.scopus.com/inward/record.url?eid=2-s2.0-84937977799&partnerID=MN8TOARS.
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  120. Ribeiro Morais G; Gano L; Kniess T; Bergmann R; Abrunhosa A; Santos I; Paulo A. "Radiosynthesis and in vivo evaluation of a ¹8F-labelled styryl-benzoxazole derivative for ß-amyloid targeting.". (2013): http://europepmc.org/abstract/med/23974304.
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  121. Simoes, Ana; Calvete, Mario; Pereira, Mariette; Llop, Jorid; Gomez-Vallejo, Vanessa; Abrunhosa, Antero J.. "Radiosynthesis of new F-18-labelled meso-tetraphenylporphyrins as potential tracers for in vivo molecular imaging with PET". Journal of Labelled Compounds and Radiopharmaceuticals (2013): https://publons.com/wos-op/publon/433393/.
  122. Alves, Vitor H.; Prata, Maria, I; Abrunhosa, Antero J.; Castelo-Branco, Miguel. "Automated 68Ga-DOTA-NOC production using a commercial synthesizer". Journal of Labelled Compounds and Radiopharmaceuticals (2013): https://publons.com/wos-op/publon/4072464/.
  123. C.F.D. Rodrigues; C.M.F. Gomes; A. Abrunhosa; M. Alves; A.M. Ribeiro; C. Monteiro; A. Paiva; I.M. Carreira; M.C. Alpoim. "473 Hexavalent Chromium, Cancer Stem Cells and Dedifferentiation –a View to a Kill!". European Journal of Cancer 48 (2012): S114-S114. https://doi.org/10.1016%2Fs0959-8049%2812%2971146-2.
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  124. Martins-Neves SR; Lopes ÁO; do Carmo A; Paiva AA; Simões PC; Abrunhosa AJ; Gomes CM. "Therapeutic implications of an enriched cancer stem-like cell population in a human osteosarcoma cell line.". (2012): http://europepmc.org/abstract/med/22475227.
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  125. Fernandes, E.; Barbosa, Z.; Clemente, G.; Alves, F.; Abrunhosa, A.J.. "Positron emitting tracers in pre-clinical drug development". Current Radiopharmaceuticals 5 2 (2012): 90-98. http://www.scopus.com/inward/record.url?eid=2-s2.0-84857135421&partnerID=MN8TOARS.
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  126. Abrunhosa, Antero; Alves, Francisco; Oxley, Ian; Boumon, Rony; Gameiro, Cristiana. "Optimization of [18F]-FDG production with terminal sterilization by autoclave". Journal of Nuclear Medicine (2012): https://publons.com/wos-op/publon/53879100/.
  127. Gomes CM; Abrunhosa AJ; Ramos P; Pauwels EK. "Molecular imaging with SPECT as a tool for drug development.". (2011): http://europepmc.org/abstract/med/20933557.
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  128. Gomes, C.M.F.; Abrunhosa, A.J.; Pauwels, E.K.J.. "Molecular imaging with SPECT and PET in exploratory investigational new drug studies". Drugs of the Future 36 1 (2011): 69-77. http://www.scopus.com/inward/record.url?eid=2-s2.0-79955995627&partnerID=MN8TOARS.
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  130. Botelho MF; Marques MA; Gomes C; da Silva AM; Bairos V; Santos Rosa MA; Abrunhosa AP; de Lima JJ. "Nanoradioliposomes molecularly modulated to study the lung deep lymphatics drainage.". (2010): http://europepmc.org/abstract/med/25965698.
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  131. Neves SR; Lopes AO; do Carmo A; Abrunhosa AJ; Simões PC; Paiva AA; Botelho MF; Gomes CM. "Osteosarcoma contains a subpopulation of cancer stem-like cells that are highly resistant to radiotherapy.". (2010): http://europepmc.org/abstract/PMC/PMC3255038.
  132. Gomes, C. M. F.; Neves, S. R. M.; Lopes, A. O. G.; do Carmo, A.; Abrunhosa, A. J.; Botelho, M.. "Assessing metabolic activity of cancer stem cells during differentiation with [F-18]FDG". European Journal of Nuclear Medicine and Molecular Imaging (2010): https://publons.com/wos-op/publon/6366036/.
  133. Neves, S. R. M.; Lopes, A. O. G.; Abrunhosa, A. J.; Simoes, P. C. P. S.; Paiva, A. A.; Botelho, M.; Gomes, C. M. F.. "Cancer stem cell populations in osteosarcoma: implications for [18F]FDG uptake and response to therapy". European Journal of Nuclear Medicine and Molecular Imaging (2010): https://publons.com/wos-op/publon/6366017/.
  134. Gomes CM; Abrunhosa AJ; Pauwels EK; Botelho MF. "P-glycoprotein versus MRP1 on transport kinetics of cationic lipophilic substrates: a comparative study using [99mTc]sestamibi and [99mTc]tetrofosmin.". (2009): http://europepmc.org/abstract/med/19409044.
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  135. Maria Filomena Rabaça Roque Botelho; Maria Alcide Tavares Marques; Célia Maria Freitas Gomes; Augusto Marques Ferreira da Silva; Vasco António Andrade Figueiredo Bairos; Manuel Amaro de Matos Santos Rosa; Antero Pena Abrunhosa; João José Pedroso de Lima. "Nanorradiolipossomas modulados molecularmente para estudar a drenagem linfática pulmonar profunda". Revista Portuguesa de Pneumologia 15 2 (2009): 261-293. https://doi.org/10.1016%2Fs0873-2159%2815%2930131-8.
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  136. Botelho, M.F.R.R.; Marques, M.A.T.; Gomes, C.M.F.; da Silva, A.M.F.; Bairos, V.A.A.F.; Rosa, M.A. de M.S.; Abrunhosa, A.P.; de Lima, J.J.P.. "Nanoradioliposomes molecularly modulated to study the lung deep lymphatic drainage | Nanorradiolipossomas modulados molecularmente para estudar a drenagem linfática pulmonar profunda". Revista Portuguesa de Pneumologia 15 2 (2009): 261-293. http://www.scopus.com/inward/record.url?eid=2-s2.0-67650327279&partnerID=MN8TOARS.
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  140. Gomes, C. M. F.; Abrunhosa, A. J.; Pauwels, E. K. J.; Botelho, M. F.. "[Tc-99m]Sestamibi vs. [Tc-99m]Tetrofosmin for functional assessment of P-glycoprotein and MRP1-mediated drug resistance in SCLC cell lines". European Journal of Nuclear Medicine and Molecular Imaging (2007): https://publons.com/wos-op/publon/6365952/.
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  148. Botelho, MF; Zeevaart, JR; Louw, WKA; Dormehl, IC; Kolar, Z; Gomez, C; Metello, L; et al. "Polyethyeneiminomethyl phosphonate (PEI-MP) for selectively targeting bone malignancies (vol 30, pg S301, 2003)". European Journal of Nuclear Medicine and Molecular Imaging (2004): https://publons.com/wos-op/publon/6365968/.
    10.1007/S00259-003-1433-5
  149. Gomes, CM; Botelho, MF; Abrunhosa, A; de Lima, JJP. "Uptake and efflux kinetics of Tc-99m-MIBI and Tc-99m-Tetrofosmin in a Pgp-expressing tumour cell line". European Journal of Nuclear Medicine and Molecular Imaging (2004): https://publons.com/wos-op/publon/6365967/.
  150. Santos RM; Barbosa RM; Antunes CM; Silva AM; Salgado AP; Abrunhosa AJ; Pereira FC; Seiça RM; Rosário LM. "Bursting electrical activity generated in the presence of KATP channel blockers. Pharmacology, sensitivity to intracellular pH and modulation by glucose metabolism.". (1997): http://europepmc.org/abstract/med/9544253.
  151. Santos, RM; Barbosa, RM; Antunes, CM; Silva, AM; Salgado, AP; Abrunhosa, AJ; Pereira, FC; Seica, RM; Rosario, LM. "Bursting electrical activity generated in the presence of K-ATP channel blockers". Advances in Experimental Medicine and Biology (1997): https://publons.com/wos-op/publon/12554458/.
    10.1007/978-1-4899-1819-2_5
  152. Rosário, L.M.; Barbosa, R.M.; Antunes, C.M.; Silva, A.M.; Abrunhosa, A.J.; Santos, R.M.. "Bursting electrical activity in pancreatic ß-cells: evidence that the channel underlying the burst is sensitive to Ca2+ influx through L-type Ca2+ channels". Pflügers Archiv European Journal of Physiology 424 5-6 (1993): 439-447. http://www.scopus.com/inward/record.url?eid=2-s2.0-0027282069&partnerID=MN8TOARS.
    10.1007/BF00374906
Capítulo de livro
  1. Francisco Zagalo; Susete Fetal; Paulo Fonte; Antero Abrunhosa; Sónia Afonso; Luís Lopes; Miguel Castelo-Branco. "Development and Testing of an MRI-Compatible Immobilization Device for Head and Neck Imaging". 2024.
    10.1007/978-3-031-49018-7_44
  2. Alves, V.H.; Abrunhosa, A.J.; Castelo-Branco, M.. "Synthesis of (R)-[N-Methyl-<sup>11</sup>C]PK11195". 93-101. 2015.
Livro
  1. Santos, R.M.; Barbosa, R.M.; Antunes, C.M.; Silva, A.M.; Salgado, A.P.; Abrunhosa, A.J.; Pereira, F.C.; Seiça, R.M.; Rosário, L.M.. Bursting electrical activity generated in the presence of KATP channel blockers: Pharmacology, sensitivity to intracellular pH and modulation by glucose metabolism. 1997.
Poster em conferência
  1. Lapo Pais, Mariana; Sereno, José Vitor Oliveira; Tomé, Vanessa A.; Fonseca, Carla; Martins, João; Fortuna, Ana; Abrunhosa, Antero; Castelo-Branco, Miguel; Gonçalves, Joana. "Negative correlation between cortical tryptophan metabolism and E/I balance in a genetic mouse model of autism spectrum disorders". Trabalho apresentado em 2nd CIBIT Meeting, 2023.
  2. Abrunhosa, Antero; Neves, Ângela; Tomé, Vanessa A.. "11C-carboxylations using Grignard reactions for the preparation of [carbonyl 11C]WAY-100635 and [1-11C]Sodium Acetate". Trabalho apresentado em 2nd CIBIT Meeting, 2023.
  3. Hrynchak, Ivanna; Silva, Magda; Silva, Sónia ; Fonseca, Alexandra; Amílcar Falcão; Abrunhosa, Antero. "GMP Production of 89Zr-DFO-Pembrolizumab for Immuno-PET: predicting response in non-small lung cancer". Trabalho apresentado em EANM, 2023.
  4. Ferreira, Hugo R. S.; Tomatis, Francesca; Almeida, Sara F.F.; Ribeiro, Ana Sofia; Ferreira, Lino; Ana Paula Silva; Moreira, João Nuno; et al. "Evaluating Blood-Brain Barrier Permeability Changes during Premetastatic Niche Formation for HER2+ Breast Cancer Brain Metastasis". Trabalho apresentado em EACR 2023 Congress, 2023.
  5. Hrynchak, Ivanna; Diana Cocioaba; Radu LEONTE; Silva, Magda; Maria-Roxana Cornoiu; Dana Niculae; Abrunhosa, Antero. "GMP Production of Copper-64 for antibody and nanobody radiolabeling: liquid vs solid target". Trabalho apresentado em 25th iSRS, 2023.
  6. Mehra, Chirag; Onwordi, Ellis; Kowalewska, Beata; Whitehurst, Thomas; Shatalina, Ekaterina; Griffioen, Gina; Martins, Ricardo; et al. "Synaptic density marker, SV2A, is reduced in autistic adults". Trabalho apresentado em INSAR meeting 2023 - International Society for Autism Research, 2023.
  7. Castelhano, Joao; Xavier, Ana Carolina; Canário, Nádia; Felix Ducker; Duarte, Isabel Catarina ; Jorge Lains; F. Carvalho; et al. "A neurostimulation and multimodal molecular imaging study of the interhemispheric inhibition/excitation imbalance in stroke". Trabalho apresentado em 5th International Brain Stimulation Conference, 2023.
  8. Lapo Pais, Mariana; Sereno, José Vitor Oliveira; Tomé, Vanessa A.; Martins, João; Abrunhosa, Antero; Gonçalves, Joana; Castelo-Branco, Miguel. "Imaging of brain tryptophan metabolism and 5-HT1A receptor density in the TSC2 mouse model: Preliminary results". Trabalho apresentado em 1º CIBIT Anual Meeting, 2022.
  9. Santos, Liliana; FERREIRA, HUGO; Tomatis, Francesca; Sereno, José Vitor Oliveira; Almeida, Sara F.F.; Ferreira, Lino; Ana Paula Silva; et al. "Impact of HER2+ brain-tropic breast cancer cells in blood-brain barrier permeability during the pre-metastatic niche formation". Trabalho apresentado em Champalimaud Research Symposium 2022, 2022.
  10. Hrynchak, Ivanna; Silva, Magda; Santos, Liliana; Amílcar Falcão; Célia Gomes; Abrunhosa, Antero. "GMP Production of 89Zr-DFO-Trastuzumab: from chemistry to the clinic". Trabalho apresentado em New Modalities in Cancer Imaging and Therapy, 2022.
  11. Santos, Liliana; Tomatis, Francesca; Ferreira, Hugo R. S.; Sereno, José Vitor Oliveira; Almeida, Sara F.F.; Ferreira, Lino; Ana Paula Silva; et al. "Trastuzumab-resistant HER2+ Brain Tropic Breast Cancer Cells Disrupt the Blood-Brain Barrier: a Potential Route for Brain Drug Delivery". Trabalho apresentado em 5th ASPIC International Congress, 2022.
  12. Hrynchak, Ivanna; Silva, Magda; Santos, Liliana; Falcao, Amilcar; Gomes, Celia; Abrunhosa, Antero. "Zr-89-immuno-PET imaging: from liquid target production to imaging". 2022.
  13. Almeida, Sara F.F.; Lima, Nuno; Oliveira, Rui; Martins-Marques, Tânia; Ribeiro-Rodrigues, Teresa; Miranda, Catarina Oliveira; Pereira de Almeida, Luis Fernando Morgado; et al. "Preconditioning mice with osteosarcoma cells-derived secretome promote tumour cells engraftment and lung metastasis development". Trabalho apresentado em Tumor Microenvironment (EACR-AACR Basic and Translational Research Conference in partnership with ASPIC), 2020.
  14. Almeida, Sara F.F.; Lima, Nuno; Oliveira, Rui; Martins-Marques, Tânia; Miranda, Catarina Oliveira; Pereira de Almeida, Luis Fernando Morgado; Amílcar, Falcão; Abrunhosa, Antero; Gomes, Célia. "Secretome derived from osteosarcoma (OS) cells promote tumour cell colonization and lung metastasis formation in pre-treated mice". Trabalho apresentado em CIBB Meeting 2019 - Universidade de Coimbra, 2019.
  15. Hrynchak, Ivanna; Ângela C.B. Neves; Pereira, M. M.; Abrunhosa, Antero; Fonseca, Inês C. F.. "Improved nucleophilic synthesis of [18F]F-DOPA using microwave technology". Trabalho apresentado em XXV Encontro Galego-Portugês de Química, Santiago de Compostela, 2019.
  16. Hrynchak, Ivanna; Neves, Ângela; Pereira, M. M.; Fonseca, Inês C. F.; Abrunhosa, Antero. "Asymmetric Synthesis of a promising [18F]F-DOPA Precursor". Trabalho apresentado em XXV Encontro Galego-Portugês de Química, Santiago de Compostela, 2019.
  17. Hrynchak, Ivanna; Neves, Ângela; Alves, Vítor H.; Pereira, M. M.; Amílcar Falcão; Abrunhosa, Antero. "Automated microwave-assisted synthesis for PET radiochemistry". Trabalho apresentado em XXV Encontro Galego-Portugês de Química, Santiago de Compostela, 2019.
  18. Almeida, Sara F.F.; Lima, Nuno; Martins-Marques, Tânia; Girao, Henrique; Miranda, Catarina Oliveira; Pereira de Almeida, Luis Fernando Morgado; Amílcar, Falcão; Abrunhosa, Antero; Gomes, Célia. "Osteosarcoma-released bioactive factors facilitate lung metastasis by regulating cell adhesion". Trabalho apresentado em Seed and Soil: mechanisms of metastasis (2nd joint EACR-MRS conference), 2019.
  19. Lapa, Beatriz; Jorge, Joana; Alves, Raquel; Pires, Ana Salomé; Abrantes, Ana Margarida; Coucelo, Margarida; Abrunhosa, Antero; et al. "Potenciais alvos terapêuticos na leucemia mieloblástica aguda - glicólise ou oxidação fosforilativa?". Trabalho apresentado em 1º Encontro Nacional de Jovens Investigadores em Oncologia, 2019.
  20. Lapa, Beatriz; Jorge, Joana; Alves, Raquel; Pires, Ana Salomé; Abrantes, Ana Margarida; Coucelo, Margarida; Abrunhosa, Antero; et al. "Glycolysis versus oxidative phosphorylation ¿ Potential therapeutic targets in AML". Trabalho apresentado em 24º European Hematology Association Congress, 2019.
  21. Alves, F.; Alves, Vítor H.; Neves, ACB; Abrunhosa, Antero J. "GMP Production of Gallium-68 from a Cyclotron Using Liquid Targets: Regulatory Aspects". Trabalho apresentado em 22nd International Symposium on Radiopharmaceutical Sciences, 2019.
  22. Cavaleiro, Carla; Jesus, Diana; Martins, João; Abrunhosa, Antero; Castelo-Branco, Miguel; Gonçalves, Joana. "Impact of neurofibromatosis type 1 on early postnatal development: a behavioral approach.". Trabalho apresentado em XVI Meeting of the Portuguese Society for Neurocience, 2019.
  23. Martins, João; Cavaleiro, Carla; Sereno, José; Edfawy, Mohamed; Peça, João; Abrunhosa, Antero; Castelo-Branco, Miguel; Gonçalves, Joana. "Neural basis for adult cognitive deficits in neurofibromatosis type 1 animal model: Relevance for autism spectrum disorders.". Trabalho apresentado em XVI Meeting of the Portuguese Society for Neurocience, 2019.
  24. Resende, Rosa; Moreira, Patricia; Ferreira-Marques, Marisa; Dinis, Teresa; Oliveira, Francisco; Sereno, José; Abrunhosa, Antero; et al. "New chimeric peptides selectively inhibit APPß cleavage decreasing Aß formation and accumulation in AD models". Trabalho apresentado em 14th International Conference on Alzheimer's & Parkinson's Diseases, Lisbon, Portugal, 2019.
  25. Ferreira, Ildete L; Maranga, Carina; Mota, Sandra I; Laço, Mário N; Sereno, José Vitor Oliveira; Abrunhosa, Antero; Hayden, Michael; Castelo-Branco, Miguel; Rego, A. Cristina. "Redox and mitochondrial function switches in striatum and cortex of pre-symptomatic and symptomatic Huntington's Disease mouse model". Trabalho apresentado em XIX National Congress of Biochemistry, 2016.
  26. Ferreira, IL; Maranga, Carina; Mota, S.I.; Laço M; Sereno, José Vitor Oliveira; Abrunhosa, Antero; Hayden M; Castelo-Branco, Miguel; Rego, Ana Cristina. "Redox and mitochondrial functional switches in striatum and cortex of pre-symptomatic and symptomatic Huntington¿s disease mouse model". Trabalho apresentado em XIX National Congress of Biochemistry by the Portuguese Society of Biochemistry, 2016.
  27. Rego, A. Cristina; Maranga, Carina; Ferreira, Ildete L; Laço, Mário N; Mota, Sandra I; Naia, L; Sereno, José Vitor Oliveira; et al. "Redox changes and bioenergetic defects in striatum and and cortex of pre-symptomatic and symptomatic Huntington's Disease mice". Trabalho apresentado em Society for Neuroscience 46th annual meeting, 2016.
  28. Rego, Ana Cristina; Ferreira, IL; Maranga, Carina; Laço Mário; Mota, S.I.; Naia Luana; Sereno, José Vitor Oliveira; et al. "Redox changes and bioenergetic defects in striatum and cortex of pre-symptomatic and symptomatic Huntington disease mice.". Trabalho apresentado em 46th Annual Meeting of Society for Neuroscience (SFN), 2016.
  29. Nuno P.F. Gonçalves; Simões, Ana V. C.; Dabrowski, Janusz; Abreu, Artur R.; Calvete, Mário J. F. ; Abrunhosa, Antero; Pereira, Mariette M.. "Synthesis of new 18F and 11C porphyrins and their potential application fo in vivo Moleucar Imaging using PET technique". Trabalho apresentado em 18th European Symposium on Organic Chemistry, 2013.
  30. Pereira, Mariette M.; Nuno P.F. Gonçalves; Simões, Ana V. C.; Abreu, Artur R.; Arnaut, Luis G.; Simões, Sérgio; Abrunhosa, Antero; Calvete, Mário J. F.. "Synthesis of carbon-11 labeled porphyrins as potential cancer biomarkers for PET imaging". Trabalho apresentado em XXIII National meeting of Portuguese Society of Chemistry, 2011.
Pré-impressão
  1. Liliana Santos; Ivanna Hrynchak; José Sereno; Hugo Ferreira; Magda Silva; Rui Almeida; Paulo Teixeira; Antero Abrunhosa; Celia Gomes. "177Lu-Trastuzumab Radionuclide Therapy: an Effective Approach for Resistant Brain Metastases in HER2+ Breast Cancer". 2025. https://doi.org/10.21203/rs.3.rs-6180100/v1.
    10.21203/rs.3.rs-6180100/v1
  2. Luís Leite; Tomás Carlos; Gustavo Campos; Helena Donato; Rodolfo Silva; Antero Abrunhosa; Lino Gonçalves; Maria João Ferreira. "Effects of successful percutaneous coronary intervention of chronic total occlusions with demonstrable viability or ischemia: A protocol for a systematic review". 2023. https://doi.org/10.1101/2023.08.01.23293494.
    10.1101/2023.08.01.23293494
  3. Alexandra I. Fonseca; Vitor H. Alves; Ivanna Hrynchak; Francisco Alves; Antero J. Abrunhosa. "Fully Automated Production of [68Ga]FAPI-46 with Gallium-68 from Cyclotron Using Liquid Targets". 2023. https://doi.org/10.20944/preprints202309.0931.v1.
    10.20944/preprints202309.0931.v1
Resumo em conferência
  1. Palma, E.; Mendes, Filipa; Guerreiro J; Campello, M.P.C.; PD Raposinho; Alves V; Abrunhosa, Antero; Paulo A. "New Cu-ATSM and Cu-GTSM Derivatives for Cancer Theranostics". Trabalho apresentado em NOVA BIOPHYSICA International Congress, Lisboa, 2019.
    Publicado
  2. Gonçalves, Joana; Violante, Inês R.; Sereno, José Vitor Oliveira; Leitão, Ricardo Alexandre; Cai, Y; Abrunhosa, Antero; Silva, AP; Silva, AJ; Castelo-Branco, Miguel. "The excitation/inhibition enigma in a mouse model of the autism spectrum disorder: evidence for distinct phenotypes of hippocampus and prefrontal cortex". Trabalho apresentado em 11th FENS - Forum of European Neuroscience, Berlin, 2018.
    Publicado
  3. Xavier, Carolina; Oliveira, Francisco; Moreira, Ana Paula; Ferreira, Rui; Mendonça, Alexandre; Verdelho, Ana; Rio, Joana; et al. "Comparação entre a PET/CT cerebral com 18F-FDG e a fase de perfusão da PET/CT com 11C-PIB". Trabalho apresentado em XVI Congresso Nacional de Medicina Nuclear, Lisboa, 2017.
    Publicado
  4. Resende, Rosa; Ferreira-Marques, Marisa; Dinis, Teresa; Oliveira, Francisco; Sereno, José; Abrunhosa, Antero; Castelo-Branco, M.; Pereira, Cláudia; Santos, Armanda. "New BACE1 inhibitors decrease Aß production and accumulation in the 3xtg-AD mouse model". Trabalho apresentado em XIX National Congress of Biochemistry, Guimarães, 2016.
    Publicado
Tese / Dissertação
  1. Neves, Ana Rita Ribeiro. "Contribuições para o desenvolvimento de um novo radiofármaco de cobre-61: [61Cu]Cu-PSMA-I¿T". Mestrado, 2022. http://hdl.handle.net/10400.22/21609.
  2. Simões, Carolina Baptista Ribeiro. "Estágio em indústria farmacêutica". Mestrado, 2021. http://hdl.handle.net/10400.21/14225.
  3. Rodrigues, Iolanda Beatriz Albuquerque. "Synthesis Optimisation of High Specific Activity Carbon-11 Radiopharmaceuticals for Brain PET Studies". Mestrado, 2020. http://hdl.handle.net/10316/90183.
  4. Fonseca, Alexandra Isabel Simões. "Labelling and validation of [61Cu]DOTA-NOC for somatostatin receptors imaging". Mestrado, 2019. http://hdl.handle.net/10316/87934.
  5. Cruz, Ângela Cristina Simões. "Investigação de um detetor não-invasivo para determinar a função de entrada em estudos PET quantitativos". Mestrado, 2018. http://hdl.handle.net/10400.26/23180.
  6. Catarino, Ana Rita. "Selective internal radiation therapy: review of the standard operating procedure for selective internal radiation therapy using SIR-Spheres microspheres labelled with Yttrium 90". Mestrado, 2017. http://hdl.handle.net/10400.26/22708.
  7. Vintém, João Paulo Nogueira, 1991-. "Desenvolvimento de um modelo dosimétrico baseado em medidas de área". Mestrado, 2015. http://hdl.handle.net/10400.26/14512.
  8. Simões, Ana Vanessa Cordeiro. "Síntese de macrociclos tetrapirrólicos fluorados. Desenvolvimento de potenciais marcadores para tomografia por emissão de positrões". Doutoramento, 2014. http://hdl.handle.net/10316/25271.
  9. Barroca, Dalila. "Estudo combinado de PET com [11C]PiB e [18F]FDG na avaliação de doença de Alzheimer". Mestrado, 2014. http://hdl.handle.net/10400.26/14488.
  10. Serra, Cristina. "Optimização e Validação da Produção de [13n]-Nh3 para Estudos Clínicos de Tomografia por Emissão de Positrões na Avaliação da Perfusão Miocárdica". Mestrado, 2014. http://hdl.handle.net/10400.22/5725.
  11. Rio, Joana Maria Teixeira Espinheira. "Importância da [11C]-Racloprida no diagnóstico de Síndromes Parkinsónicos com tomografia por emissão de positrões (PET)". Mestrado, 2014. http://hdl.handle.net/10400.26/17038.
  12. Clemente, Gonçalo dos Santos. "Synthesis of optimization of [11C] Pittsburgh compound B by the captive solvent method". Mestrado, 2013. http://hdl.handle.net/10400.21/2314.
  13. Moreira, Hugo Manuel Ramos. "Cyclotron Production of 68Ga using a 68Zn-based liquid target". Mestrado, 2013. http://hdl.handle.net/10316/32456.
  14. Alves, Vítor Hugo Pereira. "Optimisation of synthesis, purification and reformulation of (R)-[N-methyl-¹¹C] PK11195 for in vivo PET imaging studies". Mestrado, 2012. http://hdl.handle.net/10316/26005.
  15. Abrunhosa, Antero José Pena Afonso de. "Métodos computacionais no desenvolvimento de radiofármacos para a tomografia por emissão de positrões.". Doutoramento, 2002. http://hdl.handle.net/10316/810.

Propriedade Intelectual

Patente
  1. Caramelo, Francisco; Oliveira, Francisco PM; Pereira, Carlos; Ferreira, Nuno; Dias, Miguel; Cruz, Angela; Abrunhosa, Antero; Moreira, Ana Paula. 2021. "NON-INVASIVE SYSTEM FOR MEASURING THE ARTERIAL INPUT FUNCTION FOR PET IMAGING". Portugal.
    Concedida/Emitida

Outros

Outra produção
  1. Prototype of an affordable pressure-controlled emergency mechanical ventilator for COVID-19. 2020. Pereira A; Lopes L; Fonte P; Póvoa P; Santos TG; Martinho A; Neves Â; et al. http://europepmc.org/abstract/PPR/PPR270077.
  2. Prototype of an affordable pressure-controlled emergency mechanical ventilator for COVID-19. We present a viable prototype of a simple mechanical ventilator intended as a last resort to ventilate COVID-19 patients. The prototype implements the pressure-controlled continuous mandatory ventilation mode (PC-CMV) with settable breathing rates, inspiration/expiration time ratios and FiO2 modulation. Although safe, the design aims to minimize the use of technical components and those used are c. 2020. Pereira, Américo; Lopes, Luís; Fonte, Paulo; Póvoa, Pedro; Santos, Telmo G.; Martinho, Alberto José Antunes Marques; Neves, Ângela; et al. http://hdl.handle.net/10362/139995.
    10.48550/arXiv.2004.00310
  3. Synthesis of (R)-[N-Methyl-11C]PK11195. 2015. Vítor H. Alves; Antero J. Abrunhosa; Miguel Castelo-Branco. https://doi.org/10.1002%2F9781118834114.ch10.
    10.1002/9781118834114.ch10
  4. Preliminary Studies of Computer Aided Ligand Design for PET. 2001. A.J. Abrunhosa; F. Brady; S. Luthra; J.J. De Lima; T. Jones. https://doi.org/10.1016%2Fb978-012285751-5%2F50011-9.
    10.1016/b978-012285751-5/50011-9
  5. Use of Information Technology in the Search for New PET Tracers. 1998. A.J. Abrunhosa; F. Brady; S.K. Luthra; H. Morris; J.J. De Lima; T. Jones. https://doi.org/10.1016%2Fb978-012161340-2%2F50042-1.
    10.1016/b978-012161340-2/50042-1
Atividades

Orientação

Título / Tema
Papel desempenhado		 Curso (Tipo)
Instituição / Organização
2023 - Atual Efficacy and Safety of 225Ac-DOTA-SP as Adjuvant Therapy in Recurrent Glioblastoma Multiforme: A Pilot Study
Orientador de Carla Margarida Alves Domingos
Universidade de Coimbra Faculdade de Medicina, Portugal
2022 - Atual PET/CT imaging biomarkers in the tumor microenvironment of patients with penile cancer
Orientador
Universidade de Coimbra Faculdade de Medicina, Portugal
2022 - Atual Targeting brain amyloid-ß oligomers with positron emission tomography in early diagnosis of Alzheimer's disease: preclinical validation and first-in-human studies.
Orientador
Universidade de Coimbra Faculdade de Medicina, Portugal
2021 - Atual ImmunoPET imaging to help predict response to first line pembrolizumab in NSCLC patients with PD-L1>=50%
Orientador de Sónia Gonçalves Silva
Universidade de Coimbra Faculdade de Medicina, Portugal
2021 - Atual Tumor-derived Exosomes as Nanotheranostic Tools for Lung Metastasis Detection and Treatment
Orientador de Diana Margarida de Almeida Rodrigues
Universidade de Coimbra Faculdade de Farmácia, Portugal
2019 - Atual Novel Metal Radiopharmaceuticals for Theranostics in Oncology and Neuroscience
Orientador
Universidade de Coimbra Faculdade de Farmácia, Portugal
2020 - 2024 Unravel the role of HER2 in breast cancer brain metastasis: a pre-clinical approach using anti-HER2 radiolabeled nanobodies
Orientador de Liliana Pereira Santos
Universidade de Coimbra Faculdade de Farmácia, Portugal
2020 - 2024 Development and validation of a new generation of copper-based radiopharmaceuticals
Orientador de Alexandra Isabel Simões Fonseca
Universidade de Coimbra Faculdade de Farmácia, Portugal
2019 - 2024 Development of a PET Probe for the Neuropeptide Y2 Receptors
Orientador
Universidade de Coimbra Faculdade de Farmácia, Portugal
2018 - 2023 Role of osteosarcoma-derived secretome and exosomes in lung-metastatic organotropism: from premetastatic niche formation to molecular imaging
Orientador
Universidade de Coimbra Faculdade de Farmácia, Portugal
2017 - 2022 Advanced microwave technology in radiopharmaceutical synthesis
Orientador
Universidade de Coimbra Faculdade de Farmácia, Portugal
2020 - 2020 Synthesis Optimisation of High Specific Activity Carbon-11 Radiopharmaceuticals for Brain PET Studies
Orientador
 Engenharia Biomédica (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2016 - 2020 New morphometric biomarkers of the cerebellum by magnetic resonance: validation in Machado-Joseph disease
Coorientador
 Ciências da Saúde (Doutoramento)
Universidade de Coimbra Faculdade de Medicina, Portugal
2016 - 2020 Production and purification of radiometals for theranostics via liquid targets in a medical cyclotron
Orientador
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2019 - 2019 Labelling and validation of [61Cu]DOTA-NOC for somatostatin receptors imaging
Orientador
 Bioquímica (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2010 - 2014 Síntese de Macrociclos Tetrapirrólicos Fluorados. Desenvolvimento de Potenciais Marcadores para Tomografia por Emissão de Positrões
Orientador
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
Distinções

Outra distinção

2008 Robalo Cordeiro Award
Sociedade Portuguesa de Pneumologia, Portugal
1999 Young Investigator Award
Society of Nuclear Medicine and Molecular Imaging, Estados Unidos
1997 Honourable mention of the Scientific Committee
Society of Nuclear Medicine and Molecular Imaging, Estados Unidos