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I am a multidisciplinary scientist with over 16 years of research experience in the academic environment. I graduated in Applied Biology in 2003 and obtained my PhD in Tissue Engineering, Regenerative Medicine and Stem Cells (at I3Bs) in 2011, both from the University of Minho. Furthermore, I developed part of my PhD research at the Universitá La Sapienza in Rome in the Stem Cells Lab under the supervision of Prof. Paolo Bianco and at the University of Beytepe in Ankara. My PhD work was focused on the development of a functional bone tissue engineering approach using chitosan derived biomaterials and human bone marrow stromal cells. From 2011 to 2016 I developed post-doc research at the I3Bs group, working with fetal stem cells and novel methodologies to biofunctionalize biomaterials. I also worked with nanoparticles for applications in biomedicine and 3D models for tumor microenvironment. During that period, I was awarded an intramural project as PI and another as Co-PI. At the end of 2016, I joined the Portuguese Catholic University research team to perform post-doc research with chitosan and codfish derived hydroxyapatite formulations to circumvent periprosthetic joint infections, with a patent submission ongoing. I am the author/co-author of 29 articles and 3 book chapters, with a h-index of 15 and to date with more than 1200 citations. I participated in several research projects as a team member and as a researcher and was involved in the organization of scientific conferences. I am an invited expert reviewer for European Commission, WHRI-ACADEMY, German Israeli Foundation for Scientific Research and Development, Romanian Executive Agency for Higher Education, Research, Development, and Innovation, and Consultancy Services for Project Peer Review of the Science Fund of the Republic of Serbia, as well as for several international journals. I also possess major experience in writing grants for FP7, and Horizon 2020, as well as for FCT. Currently, I am a Researcher at the Genetic Dynamics of Cancer Cells Group at i3S/IPATIMUP. My main research interests are the study of the biodistribution of pancreatic cancer exosomes during disease progression and to understand how impairing these communication routes may hamper tumor growth, metastasis, and improve therapy response.
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Identificação

Identificação pessoal

Nome completo
Ana Rita da Costa Pinto
Data de nascimento
1980/12/22
Género
Feminino

Nomes de citação

  • Costa-Pinto, Ana Rita

Identificadores de autor

Ciência ID
1313-66B7-2A1E
ORCID iD
0000-0002-4764-8539
Google Scholar ID
zrkz17kAAAAJ&hl
Researcher Id
I-7483-2013
Scopus Author Id
24390737500

Endereços de correio eletrónico

  • anap@ipatimup.pt (Profissional)
  • a.r.cpinto@gmail.com (Pessoal)

Telefones

Telefone
  • 220408800 Ext.: 6178 (Profissional)

Moradas

  • Rua Júlio Amaral de Carvalho 45, 4200-135, Porto, Porto, Portugal (Profissional)

Websites

Domínios de atuação

  • Ciências Médicas e da Saúde - Biotecnologia Médica - Biomateriais
  • Ciências Médicas e da Saúde - Medicina Clínica - Oncologia
  • Ciências da Engenharia e Tecnologias - Nanotecnologia - Nanomateriais
  • Ciências Médicas e da Saúde - Biotecnologia Médica - Tecnologias que envolvem a Manipulação de Células,Tecidos,Órgãos ou todo o Organismo

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2)
Italiano Utilizador elementar (A2) Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A2) Utilizador elementar (A1)
Espanhol; Castelhano Utilizador elementar (A2) Utilizador independente (B1) Utilizador elementar (A2) Utilizador independente (B1) Utilizador elementar (A1)
Francês Utilizador elementar (A1) Utilizador elementar (A2) Utilizador elementar (A1) Utilizador elementar (A2) Utilizador elementar (A1)
Formação
Grau Classificação
2015 - 2015
Frequentou
 I Course on Advanced Widefield and Confocal Microscopy and STED Super-Resolution (Outros)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2006 - 2011
Concluído
 Engenharia de Tecidos, Medicina Regenerativa e Células Estaminais (Doutoramento)
Universidade do Minho, Portugal
"Potential of human bone marrow derived stem cells combined with chitosan based biodegradable scaffolds for bone tissue engineering" (TESE/DISSERTAÇÃO)
 Aprovada
2008 - 2008
Frequentou
 FEBS advanced course “QCM, SPR/elipsometer & AMF as novel Biosensors & Imaging Systems" (Postgraduate Certificate)
Hacettepe Üniversitesi, Turquia
2006 - 2006
Frequentou
 Course on Laboratory Animal Science”, level C FELASA (Pós-Graduação)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2005 - 2005
Frequentou
 12th Cirmib Biomaterials School and 1st Expertissues: From Biomedical Devices to Molecular Recognition and Tissue Engineered Products (Outros)
Università degli Studi di Trento, Itália
2004 - 2004
Frequentou
 Microarrays: Principles and Applications in Medicine (Outros)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
1998 - 2003
Concluído
 Biologia Aplicada (Licenciatura)
Universidade do Minho, Portugal
"Study of the gene DHCR7" (TESE/DISSERTAÇÃO)
 15
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2019/03/18 - Atual Investigador Contratado (Investigação) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
2016/11/01 - 2019/03/17 Pós-doutorado (Investigação) Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal
2013/03 - 2016/10 Pós-doutorado (Investigação) Fundação para a Ciência e a Tecnologia, Portugal
Universidade do Minho, Portugal
2011/07 - 2013/02 Pós-doutorado (Investigação) Biomaterials Biodegradables and Biomimetics, Portugal
Universidade do Minho, Portugal
2006 - 2011 Investigador (Investigação) Fundação para a Ciência e a Tecnologia, Portugal
Universidade do Minho, Portugal
2004/11 - 2005/12 Investigador (Investigação) Biomaterials Biodegradables and Biomimetics, Portugal
Universidade do Minho, Portugal
2004/01 - 2004/10 Investigador (Investigação) Universidade do Minho Centro de Engenharia Biológica, Portugal
Universidade do Minho, Portugal
Projetos

Bolsa

Designação Financiadores
2016 - 2019 Bioengineered Therapies for Infectious Diseases and Tissue Regeneration
NORTE-01-0145-FEDER-000012
Bolseiro de Pós-Doutoramento
Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal
 Comissao de Coordenacao e Desenvolvimento Regional do Norte
Em curso
2016 - 2017 STEM4CDH – Fetal Stem Cells as Therapeutic Strategy for Pulmonary Hypoplasia in Congenital Diaphragmatic Hernia
ICVS/3Bs Associated Lab Grants 2016
Orientador
Biomaterials Biodegradables and Biomimetics, Portugal
Concluído
2014 - 2015 ARTHYMUS - Artificial thymus conception: a tissue engineering strategy.
ICVS/3Bs Associated Lab Grants 2014
Orientador
Concluído
2014 - 2015 3DTumours - Development of a 3D culture system for the in vitro study of tumor pathophysiology.
ICVS/3Bs Associated Lab Grants 2014
Investigador
Concluído
2011 - 2012 3D patterned co-culture system to develop vascularized engineered bone
PTDC/EME-MFE/108892/2008
Bolseiro de Pós-Doutoramento
Biomaterials Biodegradables and Biomimetics, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2004 - 2005 Adult Mesenchymal Stem Cells Engineering for Connective Tissue Disorders. From the Bench to the Bed Side
LSHB-CT-2007-033168
Bolseiro de Investigação
Biomaterials Biodegradables and Biomimetics, Portugal
 European Commission Seventh Framework Programme for Research and Technological Development Research Potential of Convergence Regions
Concluído

Projeto

Designação Financiadores
2019/03 - Atual Terapias Dirigidas a Rede de Comunicação Mediada por Exossomas em Cancro Pancreático
POCI-01-0145-FEDER-032189
Investigador
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2013 - 2015 Maxillofacial Reconstruction using regenerative therapies: from Stem Cells to pre-Clinical Trials
PTDC/SAU-ENB/115179/2009
Bolseiro de Pós-Doutoramento
Biomaterials Biodegradables and Biomimetics, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2011 - 2011 Mastering sweet cell-instructive biosystems by copycat nano-interaction of cells with natural surfaces for biotechnological applications
NMP4-SL-2009-229292
Bolseiro de Pós-Doutoramento
Biomaterials Biodegradables and Biomimetics, Portugal
 European Commission Seventh Framework Programme for Research and Technological Development Environment
Concluído
Produções

Publicações

Artigo em conferência
  1. Rodrigues, Dina; Pinto, Ana Rita; Amorim, Maria; Rocha-Santos, Teresa; Costa, João; Silva, Artur; Duarte, Armando; Gomes, Ana Maria; Freitas, Ana Cristina. "Structural and cytotoxic characterization of sargassum muticum and osmundea pinnatifida enzymatic extraxts with biological properties". 2017.
  2. Costa-Pinto, Ana R.; Lemos, Ana L.; Piccirillo, Clara; Tavaria, Freni K; Pintado, Manuela E.. "Chitosan and codfish hydroxyapatite formulation to be used as coating material to circumvent periprosthetic joint infections". 2017.
  3. Pinto, Ana. "Biological performance of human bone marrow mesenchymal stem cells cultured onto novel chitosan polyester scaffolds". 2012.
    10.1002/term.1608
Artigo em revista
  1. Ruivo, Carolina F; Bastos, Nuno; Adem, Barbara; Batista, Ines; Duraes, Cecilia; Melo, Carlos A; Castaldo, Stephanie A; et al. "Extracellular Vesicles from Pancreatic Cancer Stem Cells Lead an Intratumor Communication Network (EVNet) to fuel tumour progression". Gut (2022): gutjnl-2021. http://dx.doi.org/10.1136/gutjnl-2021-324994.
    10.1136/gutjnl-2021-324994
  2. A. R. Costa-Pinto; Ana Luísa Lemos; Freni Kekhasharú Tavaria; Manuela Pintado. "Chitosan and Hydroxyapatite Based Biomaterials to Circumvent Periprosthetic Joint Infections". Materials (2021): https://www.mdpi.com/1996-1944/14/4/804.
    10.3390/ma14040804
  3. Costa-Pinto, Ana Rita. "In situ forming silk sericin-based hydrogel: A novel wound healing biomaterial". (2021):
    Aceite para publicação
  4. Ana do Paço; Simone Aparecida de Bessa Garcia; Joana Leitão Castro; A. R. Costa-Pinto; Renata Freitas. "Roles of the HOX Proteins in Cancer Invasion and Metastasis". Cancers (2020): https://www.mdpi.com/2072-6694/13/1/10.
    10.3390/cancers13010010
  5. Rajbux, Chandisree; Pereira, Joel; Selbourne, Maria do Céu; Costa-Pinto, Ana Rita; Poças, Fátima. "Assessment of baby Bibs. GC-MS screening, migration into saliva and insight of toxicity with QSAR tools". Food Control 109 (2020): 106951. http://dx.doi.org/10.1016/j.foodcont.2019.106951.
    10.1016/j.foodcont.2019.106951
  6. Dias, Juliana R.; Ribeiro, Nilza; Baptista-Silva, Sara; Costa-Pinto, Ana Rita; Alves, Nuno; Oliveira, Ana L.. "In situ Enabling Approaches for Tissue Regeneration: Current Challenges and New Developments". Frontiers in Bioengineering and Biotechnology 8 (2020): http://dx.doi.org/10.3389/fbioe.2020.00085.
    Acesso aberto • Publicado • 10.3389/fbioe.2020.00085
  7. Guedes, Marta; Costa-Pinto, Ana R.; Gonçalves, Virgínia M. F.; Moreira-Silva, Joana; Tiritan, Maria Elizabeth; Reis, Rui L.; Ferreira, Helena; Neves, Nuno M.. "Sardine Roe as a Source of Lipids To Produce Liposomes". ACS Biomaterials Science & Engineering 6 2 (2020): 1017-1029. http://dx.doi.org/10.1021/acsbiomaterials.9b01462.
    10.1021/acsbiomaterials.9b01462
  8. Serôdio, Ricardo; Schickert, Sónia L.; Costa-Pinto, Ana R.; Dias, Juliana R.; Granja, Pedro L.; Yang, Fang; Oliveira, Ana L.. "Ultrasound sonication prior to electrospinning tailors silk fibroin/PEO membranes for periodontal regeneration". Materials Science and Engineering: C 98 (2019): 969-981. http://dx.doi.org/10.1016/j.msec.2019.01.055.
    10.1016/j.msec.2019.01.055
  9. Casanova, Marta R.; Alves da Silva, Marta; Costa-Pinto, Ana R.; Reis, Rui L.; Martins, Albino; Neves, Nuno M.. "Chondrogenesis-inductive nanofibrous substrate using both biological fluids and mesenchymal stem cells from an autologous source". Materials Science and Engineering: C 98 (2019): 1169-1178. http://dx.doi.org/10.1016/j.msec.2019.01.069.
    10.1016/j.msec.2019.01.069
  10. Rodrigues, Dina; Costa-Pinto, Ana R.; Sousa, Sérgio; Vasconcelos, Marta W.; Pintado, Manuela M.; Pereira, Leonel; Rocha-Santos, Teresa; et al. "Sargassum muticum and Osmundea pinnatifida Enzymatic Extracts: Chemical, Structural, and Cytotoxic Characterization". Marine Drugs 17 4 (2019): 209. http://dx.doi.org/10.3390/md17040209.
    10.3390/md17040209
  11. Geão, Catarina; Costa-Pinto, Ana R.; Cunha-Reis, Cassilda; Ribeiro, Viviana P.; Vieira, Sílvia; Oliveira, Joaquim M.; Reis, Rui L.; Oliveira, Ana L.. "Thermal annealed silk fibroin membranes for periodontal guided tissue regeneration". Journal of Materials Science: Materials in Medicine 30 2 (2019): http://dx.doi.org/10.1007/s10856-019-6225-y.
    10.1007/s10856-019-6225-y
  12. Cartaxo, Ana Luísa; Costa-Pinto, Ana R.; Martins, Albino; Faria, Susana; Gonçalves, Virgínia M. F.; Tiritan, Maria Elizabeth; Ferreira, Helena; Neves, Nuno M.. "Influence of PDLA nanoparticles size on drug release and interaction with cells". Journal of Biomedical Materials Research Part A 107 3 (2018): 482-493. http://dx.doi.org/10.1002/jbm.a.36563.
    10.1002/jbm.a.36563
  13. Pinto, Ana. "Electrospun Nanofibrous Meshes Cultured With Wharton's Jelly Stem Cell: An Alternative for Cartilage Regeneration, Without the Need of Growth Factors.". Biotechnology journal (2017): http://europepmc.org/abstract/med/28902474.
    10.1002/biot.201700073
  14. Pinto, Ana. "In vitro chondrogenic commitment of human Wharton's jelly stem cells by co-culture with human articular chondrocytes". (2015): http://onlinelibrary.wiley.com/doi/10.1002/term.2085/abstract.
    10.1002/term.2085
  15. Pinto, Ana. "Hierarchical scaffolds enhance osteogenic differentiation of human Wharton’s Jelly derived Stem Cells". Biofabrication (2015): http://iopscience.iop.org/article/10.1088/1758-5090/7/3/035009/meta;jsessionid=C7A5303AE6E02D39AF318D7EE34C8E5F.c3.iopscience.cld.iop.org.
    10.1088/1758-5090/7/3/035009
  16. Alves da Silva, M.L.; Costa-Pinto, A.R.; Martins, A.; Correlo, V.M.; Sol, P.; Bhattacharya, M.; Faria, S.; Reis, R.L.; Neves, N.M.. "Conditioned medium as a strategy for human stem cells chondrogenic differentiation". Journal of Tissue Engineering and Regenerative Medicine 9 6 (2015): 714-723. http://www.scopus.com/inward/record.url?eid=2-s2.0-84930979489&partnerID=MN8TOARS.
    10.1002/term.1812
  17. Oliveira, C.; Costa-Pinto, A.R.; Reis, R.L.; Martins, A.; Neves, N.M.. "Biofunctional nanofibrous substrate comprising immobilized antibodies and selective binding of autologous growth factors". Biomacromolecules 15 6 (2014): 2196-2205. http://www.scopus.com/inward/record.url?eid=2-s2.0-84902124225&partnerID=MN8TOARS.
    10.1021/bm500346s
  18. Costa-Pinto, A.R.; Martins, A.M.; Castelhano-Carlos, M.J.; Correlo, V.M.; Sol, P.C.; Longatto-Filho, A.; Battacharya, M.; Reis, R.L.; Neves, N.M.. "In vitro degradation and in vivo biocompatibility of chitosan-poly(butylene succinate) fiber mesh scaffolds". Journal of Bioactive and Compatible Polymers 29 2 (2014): 137-151. http://www.scopus.com/inward/record.url?eid=2-s2.0-84896725288&partnerID=MN8TOARS.
    10.1177/0883911514521919
  19. Costa-Pinto, A.R.; Vargel, I.; Tuzlakoglu, K.; Correlo, V.M.; Sol, P.C.; Faria, S.; Piskin, E.; Reis, R.L.; Neves, N.M.. "Influence of scaffold composition over in vitro osteogenic differentiation of hBMSCs and in vivo inflammatory response". Journal of Biomaterials Applications 28 9 (2014): 1430-1442. http://www.scopus.com/inward/record.url?eid=2-s2.0-84898975588&partnerID=MN8TOARS.
    10.1177/0885328213512385
  20. Martins, A.M.; Kretlow, J.D.; Costa-Pinto, A.R.; Malafaya, P.B.; Fernandes, E.M.; Neves, N.M.; Alves, C.M.; et al. "Gradual pore formation in natural origin scaffolds throughout subcutaneous implantation". Journal of Biomedical Materials Research - Part A 100 A 3 (2012): 599-612. http://www.scopus.com/inward/record.url?eid=2-s2.0-84856214868&partnerID=MN8TOARS.
    10.1002/jbm.a.33261
  21. Costa-Pinto, A.R.; Correlo, V.M.; Sol, P.C.; Bhattacharya, M.; Srouji, S.; Livne, E.; Reis, R.L.; Neves, N.M.. "Chitosan-poly(butylene succinate) scaffolds and human bone marrow stromal cells induce bone repair in a mouse calvaria model". Journal of Tissue Engineering and Regenerative Medicine 6 1 (2012): 21-28. http://www.scopus.com/inward/record.url?eid=2-s2.0-80053033521&partnerID=MN8TOARS.
    10.1002/term.391
  22. Alves da Silva, M.L.; Martins, A.; Costa-Pinto, A.R.; Correlo, V.M.; Sol, P.; Bhattacharya, M.; Faria, S.; Reis, R.L.; Neves, N.M.. "Chondrogenic differentiation of human bone marrow mesenchymal stem cells in chitosan-based scaffolds using a flow-perfusion bioreactor". Journal of Tissue Engineering and Regenerative Medicine 5 9 (2011): 722-732. http://www.scopus.com/inward/record.url?eid=2-s2.0-80053146421&partnerID=MN8TOARS.
    10.1002/term.372
  23. Costa-Pinto, A.R.; Reis, R.L.; Neves, N.M.. "Scaffolds based bone tissue engineering: The role of chitosan". Tissue Engineering - Part B: Reviews 17 5 (2011): 331-347. http://www.scopus.com/inward/record.url?eid=2-s2.0-80052982295&partnerID=MN8TOARS.
    10.1089/ten.teb.2010.0704
  24. Correlo, V.M.; Costa-Pinto, A.R.; Sol, P.; Covas, J.A.; Bhattacharya, M.; Neves, N.M.; Reis, R.L.. "Melt Processing of Chitosan-Based Fibers and Fiber-Mesh Scaffolds for the Engineering of Connective Tissues". Macromolecular Bioscience 10 12 (2010): 1495-1504. http://www.scopus.com/inward/record.url?eid=2-s2.0-78649871051&partnerID=MN8TOARS.
    10.1002/mabi.201000011
  25. Alves Da Silva, M.L.; Martins, A.; Costa-Pinto, A.R.; Costa, P.; Faria, S.; Gomes, M.; Reis, R.L.; Neves, N.M.. "Cartilage tissue engineering using electrospun PCL nanofiber meshes and MSCs". Biomacromolecules 11 12 (2010): 3228-3236. http://www.scopus.com/inward/record.url?eid=2-s2.0-78650288788&partnerID=MN8TOARS.
    10.1021/bm100476r
  26. Costa-Pinto, A.R.; Correlo, V.M.; Sol, P.C.; Bhattacharya, M.; Charbord, P.; Delorme, B.; Reis, R.L.; Neves, N.M.. "Osteogenic differentiation of human bone marrow mesenchymal stem cells seeded on melt based chitosan scaffolds for bone tissue engineering applications". Biomacromolecules 10 8 (2009): 2067-2073. http://www.scopus.com/inward/record.url?eid=2-s2.0-68849110473&partnerID=MN8TOARS.
    10.1021/bm9000102
  27. Correlo, V.M.; Boesel, L.F.; Pinho, E.; Costa-Pinto, A.R.; Alves Da Silva, M.L.; Bhattacharya, M.; Mano, J.F.; Neves, N.M.; Reis, R.L.. "Melt-based compression-molded scaffolds from chitosan-polyester blends and composites: Morphology and mechanical properties". Journal of Biomedical Materials Research - Part A 91 2 (2009): 489-504. http://www.scopus.com/inward/record.url?eid=2-s2.0-70349451980&partnerID=MN8TOARS.
    10.1002/jbm.a.32221
  28. Oliveira, J.T.; Correlo, V.M.; Sol, P.C.; Costa-Pinto, A.R.; Malafaya, P.B.; Salgado, A.J.; Bhattacharya, M.; et al. "Assessment of the suitability of chitosan/polybutylene succinate scaffolds seeded with mouse mesenchymal progenitor cells for a cartilage tissue engineering approach". Tissue Engineering - Part A. 14 10 (2008): 1651-1661. http://www.scopus.com/inward/record.url?eid=2-s2.0-53049107204&partnerID=MN8TOARS.
    10.1089/ten.tea.2007.0307
  29. Costa-Pinto, A.R.; Salgado, A.J.; Correlo, V.M.; Sol, P.; Bhattacharya, M.; Charbord, P.; Reis, R.L.; Neves, N.M.. "Adhesion, proliferation, and osteogenic differentiation of a mouse mesenchymal stem cell line (BMC9) seeded on novel melt-based chitosan/polyester 3D porous scaffolds". Tissue Engineering - Part A. 14 6 (2008): 1049-1057. http://www.scopus.com/inward/record.url?eid=2-s2.0-45549109159&partnerID=MN8TOARS.
    10.1089/ten.tea.2007.0153
  30. Azevedo, N. F.; Pinto, A. R.; Reis, N. M.; Vieira, M. J.; Keevil, C. W.. "Shear Stress, Temperature, and Inoculation Concentration Influence the Adhesion of Water-Stressed Helicobacter pylori to Stainless Steel 304 and Polypropylene". Applied and Environmental Microbiology 72 4 (2006): 2936-2941. http://dx.doi.org/10.1128/aem.72.4.2936-2941.2006.
    10.1128/aem.72.4.2936-2941.2006
Capítulo de livro
  1. Alves Da Silva, Marta L.; Martins, Albino; Costa-Pinto, Ana; Reis, Rui L.; Neves, Nuno M.. "In Vitro Biological Testing in the Development of New Devices". In Biomaterials from Nature for Advanced Devices and Therapies, 532-550. John Wiley & Sons, Inc., 2016.
    10.1002/9781119126218.ch28
  2. Costa-Pinto, Ana; Santos, T. C.; Neves, N. M.; Reis, R. L.; Pinto, Ana. "Testing natural biomaterials in animal models". Portugal: John Wiley & Sons, 2016.
    10.1002/9781119126218.ch30
  3. Martins, Albino; da Silva, Marta Alves; Costa-Pinto, Ana; Reis, Rui L.; Neves, Nuno M.. "Bio-Inspired Integration of Natural Materials". In Bio-inspired Materials for Biomedical Engineering, 125-150. John Wiley & Sons, Inc., 2014.
    10.1002/9781118843499.ch8
Poster em conferência
  1. Costa-Pinto, Ana Rita. "Safety assessment of Baby bibs as food contact materials by QSAR approach and in vitro cytotoxicity assay". Trabalho apresentado em MATBIM2019, 2019.
  2. Costa-Pinto, Ana Rita. "Production of chitosan and codfish derived hydroxyapatite formulations to circumvent prosthetic joint infections". Trabalho apresentado em Encontro Ciência 2018, 2018.
  3. Costa-Pinto, Ana Rita. "Development of chitosan and codfish hydroxyapatite pastes to evade prosthetic joint infections". Trabalho apresentado em MISSION 10.000 Conference, 2018.
  4. Costa-Pinto, Ana Rita. "In-situ forming silk sericin-based hydrogel for chronic wound healing". Trabalho apresentado em CESB 2017 - 6th China-Europe Symposium on Biomaterials in Regenerative Medicine, 2017.
  5. Costa-Pinto, Ana Rita. "Ultrasound Sonication Effects on Electrospun Silk-based Membranes for Periodontal Regeneration". Trabalho apresentado em CESB 2017 - 6th China-Europe Symposium on Biomaterials in Regenerative Medicine, 2017.
  6. Costa-Pinto, Ana Rita. "Human amniotic membrane stem cells isolation and characterization". Trabalho apresentado em Term Stem 2017, 2017.
  7. Costa-Pinto, Ana Rita. "Sardine roe: a potential source of lipids for biomedical applications". Trabalho apresentado em Term Stem 2017, 2017.
  8. Costa-Pinto, Ana Rita. "Development of chitosan and codfish hydroxyapatite formulations to circumvent prosthetic joint infections". Trabalho apresentado em ISBMS, 2017.
  9. Costa-Pinto, Ana Rita. "Structural and cytotoxic characterization of Sargassum muticum and Osmundea pinnatifida enzymatic extracts with biological properties". Trabalho apresentado em Microbiotec17, 2017.
  10. Ota, T.; Enoki, S.. "Chitosan and codfish hydroxyapatite formulation to be used as coating material to circumvent periprosthetic joint infections". Trabalho apresentado em Microbiotec17, 2017.
    10.2495/dn100281
  11. Costa-Pinto, Ana Rita. "Chondrogenesis-inductive nanofibrous substrate comprising autologous TGF-¿3 and IGF-I from platelet lysates". Trabalho apresentado em Term Stem 2016, 2016.
  12. Costa-Pinto, Ana Rita. "Isolation and validation of fish roe derived-lipids for biomedical applications". Trabalho apresentado em Term Stem 2016, 2016.
  13. Costa-Pinto, Ana Rita. "ARTHYMUS - artificial thymus conception: a tissue engineering strategy". Trabalho apresentado em 4thTERMIS World Congress, 2015.
  14. Costa-Pinto, Ana Rita. "Selective immobilization of PRP-derived growth factors at the surface of nanofibrous substrates for Tissue Engineering and Regenerative Medicine". Trabalho apresentado em Society for Biomaterials 2014, 2014.
  15. Costa-Pinto, Ana Rita. "Osteogenic potential of human Wharton´s Jelly stem cells on hierarchical starch based scaffolds and its in vivo host response". Trabalho apresentado em Term Stem 2013, 2013.
  16. Costa-Pinto, Ana Rita. "Influence of conditioned medium in cartilage-like tissue production in co-cultures of articular chondrocytes and Wharton Jelly derived stem cells". Trabalho apresentado em 4th Joint ESAO-IFAO Congress 2011, 2011.
  17. Costa-Pinto, Ana Rita. "Chondrogenic differentiation of human bone marrow mesenchymal stem cells in chitosan based scaffolds". Trabalho apresentado em ICRS 2010 Meeting, 2010.
  18. Costa-Pinto, Ana Rita. "Effects of Co-Culture Conditions on Chondrogenic Commitment of Human Wharton Jelly Stem Cells". Trabalho apresentado em ICRS 2010 Meeting, 2010.
  19. Costa-Pinto, Ana Rita. "The Culture of Human Mesenchymal Stem Cells on Chitosan based Scaffolds in a Multi-Chamber Flow Perfusion Bioreactor for Bone Tissue Engineering". Trabalho apresentado em 2nd TERMIS World Congress, 2009.
  20. Costa-Pinto, Ana Rita. "In Vivo Responsive Scaffolds with the Ability of In Situ Pore Formation: A Novel Strategy for Bone Tissue Engineering". Trabalho apresentado em 2nd TERMIS World Congress, 2009.
  21. Costa-Pinto, Ana Rita. "Engineering three-dimensional bone tissue in vitro using chitosan melt based biodegradable scaffolds and hBMSCs". Trabalho apresentado em Genostem 3rd Workshop on Mesenchymal Stem Cells Engineering for Connective Tissue Disorders, 2007.
  22. Peng, Lin; Zhuo, Ren-Xi. "Biological Evaluation of Porous Chitosan/collagen Scaffolds for Periodontal Tissue Engineering". Trabalho apresentado em Day of School of Engineering of University of Minho, Guimarães, 2007.
    10.1109/icbbe.2008.220
  23. Costa-Pinto, Ana Rita. "In vivo testing of chitosan based scaffolds for bone tissue engineering". Trabalho apresentado em Genostem 4th Workshop on Mesenchymal Stem Cells Engineering for Connective Tissue Disorders, 2007.
  24. Costa-Pinto, Ana Rita. "Human Bone Marrow Mesenchymal Stem Cells Differentiation when seeded onto Novel Chitosan-Polyesters fiber mesh Scaffolds: A Bone Tissue Engineering Approach". Trabalho apresentado em 1st Annual Meeting of Portuguese Society for Stem Cells and Cell Therapy (SPCE-TC), 2006.
  25. Costa-Pinto, Ana Rita. "Human Bone Marrow Stromal Cells (hBMSCs) Response to Different Electrospun Nanofiber Meshes Topographies: a Study Focusing on the Osteogenic and Chondrogenic Differentiation Potential". Trabalho apresentado em 1st Annual Meeting of Portuguese Society for Stem Cells and Cell Therapy (SPCE-TC), 2006.
  26. Costa-Pinto, Ana Rita. "Study of the Osteogenic Behaviour of Primary Cultures of Human Bone Marrow MSCs seeded onto Chitosan-Polyester based Scaffolds". Trabalho apresentado em Genostem 2nd Workshop on Mesenchymal Stem Cells Engineering for Connective Tissue Disorders, 2006.
  27. Costa-Pinto, Ana Rita. "Factors affecting the adhesion of water stressed Helicobacter pylori to plumbing materials". Trabalho apresentado em European Helicobacter Study Group (EHSG) XVIII International Workshop, 2005.
    10.1111/j.1523-5378.2005.00342.x
  28. Costa-Pinto, Ana Rita. "Novel 3-D Chitosan/Polyester Scaffolds for Bone and Cartilage Tissue Engineering". Trabalho apresentado em 19th European Conference on Biomaterials, 2005.
  29. Costa-Pinto, Ana Rita. "Preliminary assessment of the behavior of chitosan/polyester scaffolds seeded with mouse mesenchymal stem cells for cartilage and bone tissue engineering". Trabalho apresentado em Sessão Pública de Apresentação da Sociedade Portuguesa de Células Estaminais e Terapia Celular, 2005.
  30. Lee, Juneseok; Easterling, Andrew. "Study of surface characteristics of water-exposed H. pylori and plumbing materials". Trabalho apresentado em IWA International Conference Biofilms 2004: Structure and Activity of Biofilms, 2004.
    10.1061/9780784412312.301

Propriedade Intelectual

Pedido provisório de patente
  1. 2019. "Paste of chitosan and hydroxyapatite, methods of obtaining and uses therof".
    Protegido
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2020 A biocompatible and injectable hydrogel for the sustained treatment of neurodegenerative diseases TERMIS European Chapter Meeting 2020
(Manchester, Reino Unido)
2019 Pancreatic Cancer Stem Cells Coordinate an Organized Exosomes Communication Network that Contributes to Pancreatic Cancer Progression ONCOLOGY SYMPOSIUM – UNIFESP - Advances in Cancer Research
(São Paulo, Brasil)
2018 BIOTHERAPIES – Bioengineered Therapies for Infectious Diseases and Tissue Regeneration 1st National Marathon of Circular Economy Projects
(Sines, Portugal)
2018 iCOD – Innovative technologies for valorization of by-products of codfish processing 1st National Marathon of Circular Economy Projects
(Sines, Portugal)
2017 Thermal Induced Silk fibroin membranes for periodontal guided tissue regeneration MATBIM 2017 conference - 4th international meeting on Material/Bioproduct Interaction
(Porto, Portugal)
2017 Mesenchymal Stem Cells as Key Tools for Cartilage and Bone Regeneration Instituto Superior Técnico
(Lisboa, Portugal)
2017 Stem Cells and Chitosan based Scaffolds for Bone Tissue Engineering Applications”, Ciclo de Seminários em Engenharia Biomédica Centre of Biotechnology and Fine Chemistry (CBQF) in Biotechnology School of Catholic University
(Porto, Portugal)
2017 Potencial de células estaminais e biomateriais à base de quitosano para engenharia de tecido ósseo Conferências em Biotecnologia, Centre of Biotechnology and Fine Chemistry (CBQF) in Biotechnology School of Catholic University
(Porto, Portugal)
2016 Chondrogenesis-inductive nanofibrous substrate comprising autologous TGF-¿3 and IGF-I from platelet lysates Chem2Nature First School
(Guimarães, Portugal)
2014 ARTHYMUS - artificial thymus conception: a tissue engineering strategy 1st ICVS-3B´s Meeting
(Braga, Portugal)
2013 Adult stem cells for TERM: sources and manipulation 3rd 3B’s symposium on Biomaterials and Stem cells in Regenerative Medicine, University of Minho
(Guimarães, Portugal)
2013 Chitosan based Scaffolds for Bone Tissue Engineering V Symposium on Bioengineering, University of Porto
(Porto, Portugal)
2012 Fetal stem cells obtained from Amniotic Fluid and Wharton´s Jelly expanded using platelet lysate for tissue engineering applications Term Stem 2012
(Guimarães, Portugal)
2012 Adult stem cells: sources and manipulation 2nd 3B’s symposium on Biomaterials and Stem cells in Regenerative Medicine, University of Minho
(Guimarães, Portugal)
2011 Degradation kinetics and host response of chitosan based scaffolds IBB 2nd Annual Scientific Meeting
(Braga, Portugal)
2011 In vitro degradation and biocompatibility of chitosan-PBS based scaffolds Week of School of Engineering of University of Minho
(Guimarães, Portugal)
2011 Chitosan based Scaffolds for Bone Tissue Engineering 1st 3B’s symposium on Biomaterials and Stem cells in Regenerative Medicine
(Guimarães, Portugal)
2011 Chitosan based Scaffolds for Bone Tissue Engineering Seminar in Centro de Biomedicina Molecular e Estrutural, University of Algarve
(Faro, Portugal)
2010 Enhanced Chondrogenic Differentiation of Human Bone Marrow Stromal Cells (hBMSCs) Seeded in Nanofiber Meshes under Flow Perfusion Stimulation 5th SPCE-TC
(Guimarães, Portugal)
2010 Co-culture of Human Wharton Jelly Stem Cells with Human Articular Chondrocytes Provides a Suitable Environment for their Chondrogenic Commitment 5th SPCE-TC
(Guimarães, Portugal)
2010 Evaluation of potential of Hiearchical starch-based fibrous scaffolds for bone tissue engineering applications TERMIS EU 2010
(Galway, Irlanda)
2010 Evaluation of the Potential of Hierarchical Starch-based Fibrous Scaffold for Bone Tissue Engineering Applications IBB 2nd Annual Scientific Meeting
(Braga, Portugal)
2010 Tissue response and in vitro degradation of chitosan-PBS based scaffolds TERMIS-AP 2010 Meeting
(Sidney, Austrália)
2010 Polycaprolactone nanofiber meshes for cartilage tissue engineering using dynamic culture TERMIS-AP 2010 Meeting
(Sidney, Austrália)
2010 Chondrogenic differentiation of human bone marrow mesenchymal stem cells in a flow perfusion bioreactor Chondrogenic differentiation of human bone marrow mesenchymal stem cells in a flow perfusion bioreactor
(Sidney, Austrália)
2009 Scaffold Composition Conditions the Osteogenic Differentiation in Flow Perfusion Culture of Human Mesenchymal Stem Cells 2nd TERMIS World Congress in conjunction with 2009 Seoul Stem Cell Symposium
(Seul, Coreia do Sul)
2008 Potential of human adult stem cells and natural-based biodegradable scaffolds for bone tissue engineering 6th Marie Curie Cutting-Edge Conference - “Stem cells: from the petri dish to the clinical application
(Faro, Portugal)
2008 Comparative study of the multidifferentiation potential of Human Wharton’s Jelly and Amniotic Fluid derived Stem Cells Termis-EU
(Porto, Portugal)
2007 Biological performance of human bone marrow mesenchymal stem cells cultured onto novel chitosan polyester scaffolds TERMIS-AP 2007 Tissue Engineering International & Regenerative Medicine Society Meeting
(Tokyo, Japão)
2006 Study of the Osteogenic Behaviour of Primary Cultures of Human Bone Marrow MSCs when seeded onto Chitosan-Polyester based Scaffolds Genostem 2nd Workshop on Mesenchymal Stem Cells Engineering for Connective Tissue Disorders
(Porto, Portugal)
2006 Study of the Osteogenic Behaviour of Adult Stem Cells and Novel Melt-Processable Chitosan-Polyester Based Scaffolds for Bone Tissue Engineering Regenerate World Congress on Tissue Engineering and Regenerative Medicine-TERMIS
(Pittsburgh, Estados Unidos)
2006 Human Bone Marrow Mesenchymal Stem Cells Differentiation when seeded onto Novel Chitosan-Polyesters fiber mesh Scaffolds: A Bone Tissue Engineering Approach ESF-EMBO Symposium Conference on Stem Cells in Tissue Engineering
(Sant Feliu de Guixols, Espanha)
2006 Gellan Gum Hydrogels as Supports for Human Articular Chondrocytes and Human Bone Marrow Cells for Cartilage Tissue Engineering Applications: A Comparative Study ESF-EMBO Symposium Conference on Stem Cells in Tissue Engineering
(Sant Feliu de Guixols, Espanha)
2005 The role of biofilms in the transmission of Helicobacter pylori through drinking water Micro-Biotec-2005 Congress
(Portugal)
2005 Preliminary Assessment of the Potential of Chitosan/Polyester Based Scaffolds for Bone and Cartilage Tissue Engineering SFB 2005
(Memphis, Estados Unidos)
2005 Evaluation of the Adhesion, Proliferation and Differentiation of a Mouse Mesenchymal Stem Cell line on Novel Chitosan/Polyester Based Scaffolds ESB 2005-19th European Conference on Biomaterials
(Sorrento, Itália)
2005 Preliminary Assessment of the Behaviour of Chitosan/Poly(Butylene Succinate) Scaffolds Seeded with Mouse Mesenchymal Stem Cells for Cartilage Tissue Engineering ESB 2005-19th European Conference on Biomaterials
(Sorrento, Itália)
2005 Behaviour of Human Bone Marrow Mesenchymal Stem Cells Seeded on Fiber Bonding Chitosan Polyester based for Bone Tissue Engineering Scaffolds 8th TESI Annual Meeting
(Shangai, China)

Orientação

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2021 - Atual Algae antioxidant and polysaccharide rich derived extracts from Fucus vesiculosus and Porphyra dioica as potential therapeutic strategies for pancreatic cancer
Coorientador de Paulo Ricardo Santos Pontes da Nova
2020 - Atual Multifunctional natural derived peptide extracts for skin care
Coorientador
 Biotechnology (Doutoramento)
Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal
2019 - Atual Novel method for prevention of Periprosthetic Joint Infections: Chitosan & Hydroxyapatite composite in paste form
Orientador
 Engenharia Biomédica
Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal
2019 - 2020 Study of chemical migration potential and cytotoxic evaluation of Baby bibs
Coorientador
 European Master of Science in Food Science, Technology and Business (BiFTec) (Mestrado)
Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal
2018 - 2018 Chitosan-based biomaterials and hydroxyapatite for bone regeneration
Orientador
 Engenharia Biomédica (Licenciatura/Bacharelato)
Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal
2017 - 2017 Cell proliferation assessment by DNA and Protein quantification
Orientador
 Engenharia Biomédica (Outra)
Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal
2015 - 2016 Establishment of endothelial and cancer cells co-culture systems
Coorientador
 Engenharia Biomédica (Mestrado)
Universidade do Minho, Portugal
2014 - 2015 Optimization of the size of biodegradable polymeric nanoparticles as intracellular drug delivery devices
Coorientador
 Engenharia Biomédica (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2013 - 2014 Immobilization of specific growth factors from platelet lysate at the surface of electrospun nanofibers for tissue engineering applications
Coorientador
 Engenharia Biomédica (Mestrado)
Universidade do Minho, Portugal
2011 - 2012 Fetal stem cells obtained from Amniotic Fluid and Wharton´s Jelly expanded using platelet lysate for tissue engineering applications
Coorientador
Biomaterials Biodegradables and Biomimetics, Portugal
2009 - 2009 Study of the behavior of human bone marrow stromal cells (hBMSC’s) through an osteogenic differentiation upon micro and nano structured polymeric surfaces
Coorientador
Biomaterials Biodegradables and Biomimetics, Portugal
2008 - 2009 Osteogenic potential of human Wharton’s jelly on stromal cells cultured on hierarchical fibrous-based scaffold
Coorientador
 Genética e Biotecnologia (Mestrado)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2008 - 2008 Adult stem cells: Isolation, culturing and differentiation
Coorientador
 Biologia Aplicada (Iniciação científica)
Universidade do Minho, Portugal
2008 - 2008 Tissue Engineering – Present or Future
Coorientador
 Medicina (Outra)
Universidade do Minho, Portugal
2007 - 2008 Effects of biomaterials on gene expression in bone marrow stromal cells and umbilical cord cells
Coorientador
Biomaterials Biodegradables and Biomimetics, Portugal
2006 - 2006 Study of the role of the bone morphogenetic proteins in spine pathology
Coorientador
 Medicina (Outra)
Universidade do Minho, Portugal

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação) 		Instituição / Organização
2017 - Atual 4rd Edition of MATBIM Packaging Material / Bioproduct Interactions (MATBIM 2017) (2017)
Conferência
 Universidade Católica Portuguesa Centro Regional do Porto, Portugal
2013 - Atual TERM STEM 2013 (2013)
Congresso (Membro da Comissão Organizadora)
 Universidade do Minho, Portugal
2011 - Atual 4th Joint ESAO-IFAO Congress 2011 and Young ESAO 2011 (2011)
Conferência (Membro da Comissão Organizadora)
 Universidade do Minho, Portugal
2008 - Atual Termis-EU 2008 (2008)
Conferência (Membro da Comissão Organizadora)
 Universidade do Minho, Portugal
2007 - Atual 2nd Workshop on Mesenchymal Stem Cells Engineering for Connective Tissue Disorders (2007)
Congresso (Membro da Comissão Organizadora)
 Universidade do Minho, Portugal
2005 - Atual 1st Annual Meeting of Portuguese Society for Stem Cells and Cell Therapy (SPCE-TC) (2005)
Congresso (Membro da Comissão Organizadora)
 Universidade do Minho, Portugal

Júri de grau académico

Tema
Tipo de participação 		Nome do candidato (Tipo de grau)
Instituição / Organização
2019 Biofunctional silk-fibroin membranes with antioxidant properties for the treatment of chronic wounds
Arguente principal
 Ana Sofia Ferreira Fernandes (Mestrado)
Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal
2018 Understanding the Potential of PDMAEMA-Based Vectors for Gene Therapy of the Retina
Arguente
 Diogo Miguel Barros Bitoque (Doutoramento)
Universidade Nova de Lisboa, Portugal
2011 Development of non-viral vectors for genetic therapy
Arguente principal
 Ana Rita Reis Mateus (Mestrado)
Universidade do Algarve - Campus de Gambelas, Portugal

Arbitragem científica em revista

Nome da revista (ISSN) Editora
2021 - Atual Molecules

Comissão de avaliação

Descrição da atividade
Tipo de assessoria 		Instituição / Organização Entidade financiadora
2020 - Atual Invited expert reviewer for Romanian Executive Agency for Higher Education, Research, Development and Innovation Funding for Experimental Demonstrative Project Call (PED 2019).
Avaliador
 Romanian Executive Agency for Higher Education, Research, Development and Innovation Funding, Roménia
2019 - Atual M.ERA-NET Call 2019
Avaliador
 Horizon 2020, Bélgica European Union
2016 - Atual Bulgarian National Science Fund (BNSF), Bilateral and Biological Sciences.
Avaliador
 German-Israeli Foundation for Scientific Research and Development, Israel
2016 - Atual 4th Call for Proposals of the International Fellowship Programme WHRI-ACADEMY (FP7 Marie Curie COFUND scheme). Queen Mary University of London, Reino Unido European Commission Seventh Framework Programme for Research and Technological Development

Consultoria / Parecer

Descrição da atividade Instituição / Organização
2020 - Atual Consultancy Services for Project Peer Review of the Science Fund of the Republic of Serbia

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2013 - 2013 Biocompatibilidade Engenharia Biomédica (Mestrado integrado) Universidade do Minho, Portugal

Entrevista / Programa (rádio / tv)

Programa Tema
2019/11/21 - Atual Programa da manhã: Dia mundial do Cancro do Pancreas A investigação no cancro do pâncreas – Dia Mundial do Cancro do Pâncreas
Distinções

Prémio

2010 Best oral presentation
Universidade do Minho, Portugal
2009 Travel award
2007 Outstanding Student/Young Investigator award for best oral presentation
2002 Student Merit award
Universidade do Minho, Portugal

Outra distinção

2020 Honored mention 4th Edition of “Prémio Rui Osório de Castro / Millennium BCP” with the work “Terapia dirigida para neuroblastoma com exossomas e RNA de interferência”