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Márcia graduated in Biochemistry at Universidade de Lisboa in 2004 and completed her PhD in Science and Animal Technology at Universidade Técnica de Lisboa in 2010. Since then, she had published 17 papers (first author of 8, h-index 10) with over 474 citations (Scopus author). Of these papers, two were published in PNAS, one in SCIENTIFIC REPORTS one in BIOORGANIC CHEMISTRY and various in JBC, JMB, BIOCHEMISTRY and FEMS, high impact factor journals in the areas of Biochemistry and Molecular Biology. During PhD developed scientific expertise in molecular and structural biology, and made several relevant contributions in the field of carbohydrate-active enzymes (CAZYmes). Márcia has several years of experience in gene cloning and expression, mutagenesis, recombinant protein expression and purification, Isothermal Titration Calorimetry (ITC), protein crystallization and X-ray crystallography. She also spent 4 months in the laboratory headed by prof. Harry Gilbert (ICMB, Newcastle University, UK), well known in the field of CAZYmes where she had the opportunity of deepening her knowledge on these proteins studying protein-carbohydrate interactions using ITC. After PhD, Márcia joined the protein crystallography group of Prof. Maria João Romão at UCIBIO, FCT-NOVA. The use of protein crystallography to solve different biological problems has been her main interest since she joined this group and, where she also had the opportunity to developed expertise in SAXS. In the past 10 years, has been involved in different topics since structural-activity studies on Nitric Oxide Synthase focused on drug design with the collaboration of Dr. João G. Correia (IST) to the structural characterization of a new periplasmic aldehyde oxidase (PaoABC) where collaborated with Dr. Silke Leimkueler (University of Potsdam, Germany). From this last collaboration one manuscript with the preliminary structural characterization of PaoABC was published in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES and another focused on the structural and functional characterization in ACS CHEMICAL BIOLOGY. Also involved in the molybdenum topic, are the ABC-transporters witch together with molybdoenzymes have been one of her main research topics. Her Ph.D. topic is still present in her actual research, maintaining an actively collaboration with Carlos Fontes group (CIISA, UTL) together with Ana Luisa Carvalho (UCIBIO-NOVA). This collaboration already provided numerous advances in the field of cellulosomics namely by revealing the mechanism of cellulosome assembly and cell surface attachment and in deciphering the role of novel CBMs in efficient polysaccharide hydrolysis by cellulolytic bacteria. From this collaboration, resulted two manuscripts, one with the ligand specificity of type A Carbohydrate-binding Modules from family 64 in the JOURNAL OF BIOLOGICAL CHEMISTRY and recently another one in INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES about novel insights in the function of a family 81 glycoside hydrolase from Clostridium thermocellum. From 2011 to present she had some teaching experience in classes of Masters in Biochemistry and Biotechnology in FCT-NOVA and was supervisor of 3 MSc thesis students. She was also involved in the INSTRUCT course, ISBio2014 and ISBio2015 where actively participated in the ITC module. During her post-doctoral period, went several times to different synchrotrons facilities to measure protein crystal samples, namely ESRF in Grenoble (France); DIAMOND in Didcot, UK; SLS in Village, Switzerland. Finally, She is a mother of two children, born in 2009 and 2014.
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Identificação

Identificação pessoal

Nome completo
Márcia Alexandra da Silva Correia

Nomes de citação

  • Correia, Márcia
  • Correia, M. A. S.

Identificadores de autor

Ciência ID
1111-FE8C-4A3D
ORCID iD
0000-0003-0636-8095
Researcher Id
D-2077-2013

Endereços de correio eletrónico

  • mad.correia@fct.unl.pt (Profissional)

Telefones

Telefone
  • 212948300 Ext.: 10962 (Profissional)

Websites

Domínios de atuação

  • Ciências Naturais - Ciências Biológicas - Bioquímica
  • Ciências Naturais - Ciências Biológicas - Biologia Molecular
  • Ciências Naturais - Ciências Biológicas - Biofísica

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Inglês Utilizador proficiente (C1) Utilizador proficiente (C2) Utilizador proficiente (C1) Utilizador proficiente (C1)
Português (Idioma materno)
Francês Utilizador elementar (A1) Utilizador elementar (A2) Utilizador elementar (A1) Utilizador independente (B1)
Formação
Grau Classificação
2010/06/01 - 2016/10/31
Concluído
 Postdoc - "Nitric oxide synthase targeting with re(i)/99mtc(i)-complexes containing l-arg derivatives: a structure-activity study" (Pós-doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2005/01 - 2010/05/14
Concluído
 Ciências Veterinárias (Doutoramento)
Especialização em Ciência e Tecnologia Animal
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
"Structural and functional insights into the role of Carbohydrate Esterases and Carbohydrate Binding Modules in Plant Cell Wall Hydrolysis" (TESE/DISSERTAÇÃO)
 Unanimously approved
1999/09 - 2004/06
Concluído
 Bioquímica (Licenciatura)
Universidade de Lisboa Faculdade de Ciências, Portugal
"Genetic polymorphisms of glutathione S-transferase in different human pathologies." (TESE/DISSERTAÇÃO)
 16
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2018/12/19 - Atual Investigador Contratado (Investigação) REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2010/06/01 - 2016/05/31 Pós-doutorado (Investigação) Fundação para a Ciência e a Tecnologia, I.P., Portugal
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2009/02/01 - 2009/03/31 Estagiário de Investigação (Investigação) Newcastle University Institute for Cell and Molecular Biosciences, Reino Unido
Newcastle University Institute for Cell and Molecular Biosciences, Reino Unido
2006/10/01 - 2007/01/31 Estagiário de Investigação (Investigação) Newcastle University Institute for Cell and Molecular Biosciences, Reino Unido
Newcastle University Institute for Cell and Molecular Biosciences, Reino Unido

Outros

Categoria Profissional
Instituição de acolhimento 		Empregador
2016/11/01 - 2018/12/18 Research fellow (BPD) (Project FCT UID/Multi/04378/2014) REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
Universidade Nova de Lisboa, Portugal
2005/01/01 - 2010/05/14 Research fellow (BD) (SFRH/BD/23784/2005) Fundação para a Ciência e a Tecnologia, I.P., Portugal
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal
Projetos

Bolsa

Designação Financiadores
2016/11/01 - 2018/12/18 Applied Molecular Biosciences Unit
UID/Multi/04378/2013
Bolseiro de Pós-Doutoramento
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
Concluído
2010/06/01 - 2016/10/31 Re(I)/99mTc(I) complexes containing L-arginine derivatives as substrates or inhibitors of Nitric Oxide Synthase: A structure-activity study
SFRH/BPD/64917/2009
Bolseiro de Pós-Doutoramento
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2006/01/01 - 2010/05/14 Structural and functional insights into the role of Carbohydrate Esterases and Carbohydrate Binding Modules in Plant Cell Wall Hydrolysis
SFRH/BD/23784/2005
Bolseiro de Doutoramento
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído

Projeto

Designação Financiadores
2018/09 - 2021 Glycan-human microbiome interaction: glycan diversity and recognition in the human gut with impact on health and nutrition
PTDC/BIA-MIB/31730/2017
Investigador
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
 Fundação para a Ciência e a Tecnologia, I.P.
Em curso
2016/01 - 2019/01 Aldehyde Oxidases in Drug Metabolism and Biocatalysis: Searching for the Substrate Specificity and Catalytic Mechanism<br>
Provided by PTCRIS: 139810
PTDC/BBB-BEP/1185/2014
Investigador
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
 Fundação para a Ciência e a Tecnologia, I.P.
Concluído
2016 - 2019 Molecular determinants of bacterial cellulosome diversity in different ecological niches.
PTDC/BIA-MIC/5947/2014
Bolseiro de Pós-Doutoramento
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal
 Fundação para a Ciência e a Tecnologia, I.P.
Concluído
2016 - 2019 Redução de CO2 para a produção de biocombustíveis sustentáveis
PTDC/BBB-EBB/2723/2014
Bolseiro de Pós-Doutoramento
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
 Fundação para a Ciência e a Tecnologia, I.P.
Concluído
2016/01 - 2018/12 An integrative structural biology approach to characterise the protein-carbohydrate microbial recognition
Provided by PTCRIS: 139494
PTDC/BBB-BEP/0869/2014
Investigador
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
 Fundação para a Ciência e a Tecnologia, I.P.
Concluído
2013/07 - 2016/06 Modern Structural Biology: Resources for the advancement of in-house X-ray Crystallography
125363
Provided by PTCRIS: 125363
RECI/BBB-BEP/0124/2012
Bolseiro de Pós-Doutoramento
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
 Fundação para a Ciência e a Tecnologia, I.P.
Concluído
2012/02 - 2015/01 Nitric Oxide Synthase targeting with Re(I)/99mTc(I)-complexes containing L-Arg derivatives: A structure-activity study
121752
Provided by PTCRIS: 121752
PTDC/BIA-PRO/118377/2010
SFRH/BPD/64917/2009
Bolseiro de Pós-Doutoramento
Fundação para a Ciência e a Tecnologia, I.P.
Concluído
2012/02 - 2015/01 Mammalian and Bacterial Aldehyde Oxidases: Structure, mechanism and insights into cofactor binding and protein maturation
Provided by PTCRIS: 118377
118377
PTDC/BIA-PRO/118377/2010
Bolseiro de Pós-Doutoramento
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
 Fundação para a Ciência e a Tecnologia, I.P.
Concluído
2009/01 - 2011/12 Structure and function of novel carbohydrate-binding modules and cohesin-dockerin protein complexes from Clostridium thermocellum
69732
Provided by PTCRIS: 69732
Bolseiro de Pós-Doutoramento
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal
 Fundação para a Ciência e a Tecnologia, I.P.
Concluído
Produções

Publicações

Artigo em revista
  1. Márcia A. S. Correia; Ana M. Gonçalves; Augusto Q. Pedro; Diana M. Oliveira; Adriana E. Oliveira; Marino F. A. Santos; João Queiroz; et al. "Thermofluor-Based Optimization Strategy for the Stabilization of Recombinant Human Soluble Catechol-O-Methyltransferase". International Journal of Molecular Sciences 23 20 (2022): 12298-12298. http://dx.doi.org/10.3390/ijms232012298.
    10.3390/ijms232012298
  2. Márcia A. S. Correia; Marlene Duarte; Victor D. Alves; Márcia Correia; Catarina Caseiro; Luís M.A. Ferreira; Maria João Romão; et al. "Structure-function studies can improve binding affinity of cohesin-dockerin interactions for multi-protein assemblies". International Journal of Biological Macromolecules (2022): http://dx.doi.org/10.1016/j.ijbiomac.2022.10.102.
    10.1016/j.ijbiomac.2022.10.102
  3. Bras, Natercia F.; Lopes, Filipa A. A.; Correia, M. A. S.; Palma, Angelina S.; Sousa, Sérgio F.; Ramos, Maria João. "Combined in silico and in vitro studies to identify novel antidiabetic flavonoids targeting glycogen phosphorylase". Bioorganic Chemistry 108 (2021): 104552-104552. http://dx.doi.org/10.1016/j.bioorg.2020.104552.
    Acesso aberto • Publicado • 10.1016/j.bioorg.2020.104552
  4. Kumar, Krishan; Correia, Márcia A.S.; Pires, Virgínia M.R.; Dhillon, Arun; Sharma, Kedar; Rajulapati, Vikky; Fontes, Carlos M.G.A.; Carvalho, Ana Luísa; Goyal, Arun. "Novel insights into the degradation of ß-1,3-glucans by the cellulosome of Clostridium thermocellum revealed by structure and function studies of a family 81 glycoside hydrolase". International Journal of Biological Macromolecules 117 (2018): 890-901. http://dx.doi.org/10.1016/j.ijbiomac.2018.06.003.
    Publicado • 10.1016/j.ijbiomac.2018.06.003
  5. Ana Rita Otrelo-Cardoso; Rashmi R. Nair; Márcia A. S. Correia; Raquel S. Correia Cordeiro; Alejandro Panjkovich; Dmitri I. Svergun; Teresa Santos-Silva; Maria G. Rivas. "Highly selective tungstate transporter protein TupA from Desulfovibrio alaskensis G20". Scientific Reports 7 1 (2017): https://doi.org/10.1038/s41598-017-06133-y.
    10.1038/s41598-017-06133-y
  6. Pires, V.M.R.; Pereira, P.M.M.; Brás, J.L.A.; Correia, M.; Cardoso, V.; Bule, P.; Alves, V.D.; et al. "Stability and ligand promiscuity of type A carbohydrate-binding modules are illustrated by the structure of Spirochaeta thermophila StCBM64C". Journal of Biological Chemistry 292 12 (2017): 4847-4860. https://doi.org/10.1074%2Fjbc.m116.767541.
    Publicado • 10.1074/jbc.M116.767541
  7. Correia, M.A.S.; Otrelo-Cardoso, A.R.; Schwuchow, V.; Sigfridsson Clauss, K.G.V.; Haumann, M.; Romão, M.J.; Leimkühler, S.; Santos-Silva, T.. "The Escherichia coli Periplasmic Aldehyde Oxidoreductase Is an Exceptional Member of the Xanthine Oxidase Family of Molybdoenzymes". ACS Chemical Biology 11 10 (2016): 2923-2935. http://www.scopus.com/inward/record.url?eid=2-s2.0-84992170557&partnerID=MN8TOARS.
    10.1021/acschembio.6b00572
  8. Otrelo-Cardoso, Ana Rita; Nair, Rashmi R.; Correia, Marcia A. S.; Rivas, Maria G.; Santos-Silva, Teresa. "TupA: A Tungstate Binding Protein in the Periplasm of Desulfovibrio alaskensis G20". International Journal of Molecular Sciences 15 7 (2014): 11783-11798. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000340038500038&KeyUID=WOS:000340038500038.
    10.3390/ijms150711783
  9. Otrelo-Cardoso, Ana Rita; da Silva Correia, Marcia Alexandra; Schwuchow, Viola; Svergun, Dmitri I.; Romao, Maria Joao; Leimkuehler, Silke; Santos-Silva, Teresa. "Structural Data on the Periplasmic Aldehyde Oxidoreductase PaoABC from Escherichia coli: SAXS and Preliminary X-ray Crystallography Analysis". International Journal of Molecular Sciences 15 2 (2014): 2223-2236. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000335776400032&KeyUID=WOS:000335776400032.
    10.3390/ijms15022223
  10. Correia, Marcia A. S.; Mazumder, Koushik; Bras, Joana L. A.; Firbank, Susan J.; Zhu, Yanping; Lewis, Richard J.; York, William S.; Fontes, Carlos M. G. A.; Gilbert, Harry J.. "Structure and Function of an Arabinoxylan-specific Xylanase". Journal of Biological Chemistry 286 25 (2011): 22510-22520.
    10.1074/jbc.M110.217315
  11. Bras, Joana L. A.; Cartmell, Alan; Carvalho, Ana Luisa M.; Verze, Genny; Bayer, Edward A.; Vazana, Yael; Correia, Marcia A. S.; et al. "Structural insights into a unique cellulase fold and mechanism of cellulose hydrolysis". Proceedings of the National Academy of Sciences of the United States of America 108 13 (2011): 5237-5242.
    Publicado • 10.1073/pnas.1015006108
  12. Bras, Joana L. A.; Correia, Marcia A. S.; Romao, Maria J.; Prates, Jose A. M.; Fontes, Carlos M. G. A.; Najmudin, Shabir. "Purification, crystallization and preliminary X-ray characterization of the pentamodular arabinoxylanase CtXyl5A from Clostridium thermocellum". Acta Crystallographica Section F-Structural Biology and Crystallization Communications 67 (2011): 833-836.
    10.1107/S1744309111020823
  13. Montanier, Cedric Y.; Correia, Marcia A. S.; Flint, James E.; Zhu, Yanping; Basle, Arnaud; McKee, Lauren S.; Prates, Jose A. M.; et al. "A Novel, Noncatalytic Carbohydrate-binding Module Displays Specificity for Galactose-containing Polysaccharides through Calcium-mediated Oligomerization". Journal of Biological Chemistry 286 25 (2011): 22499-22509.
    10.1074/jbc.M110.217372
  14. Brás, J.L.A.; Cartmell, A.; Carvalho, A.L.M.; Verzé, G.; Bayer, E.A.; Vazana, Y.; Correia, M.A.S.; et al. "Structural insights into a unique cellulase fold and mechanism of cellulose hydrolysis (Proceedings of the National Academy of Sciences of the United States of America (2011) 108, 13, (5237-5242))". Proceedings of the National Academy of Sciences of the United States of America 108 20 (2011): 8525-8525. http://www.scopus.com/inward/record.url?eid=2-s2.0-79957764741&partnerID=MN8TOARS.
    10.1073/pnas.1104766108
  15. Correia, Marcia A. S.; Abbott, D. Wade; Gloster, Tracey M.; Fernandes, Vania O.; Prates, Jose A. M.; Montanier, Cedric; Dumon, Claire; et al. "Signature Active Site Architectures Illuminate the Molecular Basis for Ligand Specificity in Family 35 Carbohydrate Binding Module". Biochemistry 49 29 (2010): 6193-6205.
    10.1021/bi1006139
  16. Correia, Marcia A. S.; Pires, Virginia M. R.; Gilbert, Harry J.; Bolam, David N.; Fernandes, Vania O.; Alves, Victor D.; Prates, Jose A. M.; Ferreira, Luis M. A.; Fontes, Carlos M. G. A.. "Family 6 carbohydrate-binding modules display multiple beta 1,3-linked glucan-specific binding interfaces". Fems Microbiology Letters 300 1 (2009): 48-57.
    10.1111/j.1574-6968.2009.01764.x
  17. Montanier, Cedric; van Bueren, Alicia Lammerts; Dumon, Claire; Flint, James E.; Correia, Marcia A.; Prates, Jose A.; Firbank, Susan J.; et al. "Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function". Proceedings of the National Academy of Sciences of the United States of America 106 9 (2009): 3065-3070.
    10.1073/pnas.0808972106
  18. Correia, Marcia A. S.; Prates, Jose A. M.; Bras, Joana; Fontes, Carlos M. G. A.; Newman, Joseph A.; Lewis, Richard J.; Gilbert, Harry J.; Flint, James E.. "Crystal structure of a cellulosomal family 3 carbohydrate esterase from Clostridium thermocellum provides insights into the mechanism of substrate recognition". Journal of Molecular Biology 379 1 (2008): 64-72.
    10.1016/j.jmb.2008.03.037
  19. Najmudin, S.; Carvalho, A.; Romão, M.; Guerreiro, C. I. P. D.; Prates, J. A. M.; Correia, M. A. S.; Alves, V.; et al. "Structure and function of PKD-CBM44 and CBM30 modules of the bifunctionalClostridium thermocellumcellulase, CtCel9D-Cel44A". Acta Crystallographica Section A Foundations of Crystallography 62 a1 (2006): s139-s139. http://dx.doi.org/10.1107/s0108767306097224.
    Publicado • 10.1107/s0108767306097224
  20. Najmudin, S; Guerreiro, CIPD; Carvalho, AL; Prates, JAM; Correia, MAS; Alves, VD; Ferreira, LMA; et al. "Xyloglucan is recognized by carbohydrate-binding modules that interact with beta-glucan chains". Journal of Biological Chemistry 281 13 (2006): 8815-8828.
    10.1074/jbc.M510559200
Poster em conferência
  1. Filipa S. S. Engrola; Correia, Márcia; Santos-Silva, Teresa; Maria Joao Romao. "New insights on the catalytic mechanism of arsenite oxidase". Trabalho apresentado em In situ Structural Biology: From Cryo-EM to Integrative Modelling, 2020.
  2. Correia, M. A. S.; Virginia M.R. Pires; Joana L.A. Brás; Pedro Bule; Maria Joao Romao; Carlos MGA Fontes. "Stability and ligand promiscuity of type A carbohydrate-binding modules are illustrated by the structure of Spirochaeta thermophila St CBM64C". Trabalho apresentado em 6th Meeting of the Synchrotron Radiation Users from Portugal (ENURS), 2017.
  3. Correia, M. A. S.; Otrelo-Cardoso, A.R; Teresa Santos-Silva. "The Tungstate ABC transporter – structure and function of the periplasmic TupA". Trabalho apresentado em 5th Meeting of the Synchrotron Radiation Users from Portugal (ENURS), 2016.
  4. Correia, M. A. S.; Otrelo-Cardoso, A.R; Teresa Santos-Silva; Maria Joao Romao. "Structural insights into a unique periplasmic aldehyde oxidoreductase from Escherichia coli". Trabalho apresentado em 6th European Conference of Chemistry for Life Sciences, 2015.
  5. Correia, M. A. S.; Otrelo-Cardoso, A.R; Teresa Santos-Silva; Maria Joao Romao. "The unique features revealed by the structure of the periplasmic aldehyde oxidoreductase from Escherichia coli". Trabalho apresentado em 4th Meeting of the Synchrotron Radiation Users from Portugal (ENURS), 2015.
  6. Correia, M. A. S.; Otrelo-Cardoso, A.R; Santos-Silva, Teresa; Maria Joao Romao. "The structure of the first heterotrimeric periplasmic aldehyde oxidoreductase from Escherichia coli.". Trabalho apresentado em 3rd Meeting of Synchrotron Radiation Users from Portugal and ESRF-Day, 2014.
  7. Correia, M. A. S.; Otrelo-Cardoso, A.R; Santos-Silva, Teresa; Maria Joao Romao; Leimkuehler, Silke. "Structure of the first monomeric periplasmic aldehyde oxidoreductase from Escherichia coli.". Trabalho apresentado em Molybdenum & Tungsten Enzymes Conference, 2013.
  8. Correia, M. A. S.; Otrelo-Cardoso, A.R; Santos-Silva, Teresa; Leimkuehler, Silke; Maria Joao Romao. "Structure of a monomeric periplasmic aldehyde oxidoreductase from Escherichia coli: Discover of an unexpected [4Fe-4S] cluster using Synchrotron radiation". Trabalho apresentado em 2nd Meeting of Synchrotron Radiation Users from Portugal and ESRF-Day, 2013.
  9. Correia, M. A. S.; Prof. José Antonio Mestre Prates, PhD; Carlos MGA Fontes. "A novel carbohydrate-binding module displays specificity for galactose-containing polysaccharides through calcium-mediated oligomerization". Trabalho apresentado em 9th Carbohydrate Bioengineering Meeting (CBM9), 2011.
  10. Correia, M. A. S.; Prof. José Antonio Mestre Prates, PhD; Gilbert, Harry J.; Carlos MGA Fontes. "A family 35 CBM from Clostridium thermocellum specifically recognizes galactose side-chains of complex polysaccharides". Trabalho apresentado em 8th Carbohydrate Bioengineering Meeting (CBM8), 2009.
  11. Catarina Guerreiro; Najmudin, Shabir; Carvalho, Ana L.; Correia, M. A. S.; Maria Joao Romao; Carlos MGA Fontes. "Structural basis for the promiscuous specificity of carbohydrate-binding modules from the beta-sandwich super-family". Trabalho apresentado em 7th Carbohydrate Bioengineering Meeting (CBM7), 2007.
  12. Correia, M. A. S.; José Mestre Prates; Carlos MGA Fontes; Gilbert, Harry J.. "Evidence that a putative new family of CBMs binds to Xyloglucan but not undecorated ß-glucan chains". Trabalho apresentado em 7th Carbohydrate Bioengineering Meeting (CBM7), 2007.
  13. José Mestre Prates; Najmudin, Shabir; Catarina Guerreiro; Carvalho, Ana Luísa; Correia, M. A. S.; Maria Joao Romao; Gilbert, Harry J.; Carlos MGA Fontes. "Crystal structure of novel CBMs that bind with equal affinity to cellulose and xyloglucan (CelJ CBM44 and CBM30)". Trabalho apresentado em XV National Congress of Biochemistry, 2006.
  14. Correia, M. A. S.; José Mestre Prates; Carlos MGA Fontes. "Identification of novel carbohydrate-binding modules (CBMs) in the cellulosome of Clostridium thermocellum". Trabalho apresentado em XV Congresso Nacional de Bioquímica, 2006.
  15. Correia, M. A. S.; Carlos MGA Fontes; José Mestre Prates. "A genome-wide search for the complete repertoire of cellulosomal enzymes in Clostridium thermocellum". Trabalho apresentado em Congresso da Sociedade Portuguesa de Ciências Veterinárias, 2005.
  16. Correia, M. A. S.; Marinho, Claudia; Bicho, Manuel. "Total plasma glutathione in hipertensive subjects: Possible association between hypertension and oxidative stress". Trabalho apresentado em XIV Congresso Nacional de Bioquímica, 2004.
  17. Correia, M. A. S.; Marinho, Claúdia; Bicho, Manuel. "Genetic distribution of GSTM1 and GSTT1 in Portuguese hipertensive disease of pregnancy". Trabalho apresentado em 14th World Congress of the International Society for the Study of Hypertension in Pregnancy, 2004.
  18. Correia, M. A. S.; Marinho, Claúdia; Bicho, Manuel. "Genetic distribution of GSTM1 and GSTT1 in hypertensive portuguese subjects: association with plasma epinephrine oxidase activity". Trabalho apresentado em Fourteenth European Meeting on Hypertension, 2004.
  19. Correia, M. A. S.; Marinho, Claúdia; Bicho, Manuel. "Genetic distribution of GSTM1 and GSTT1 in different Portuguese populations: association with plasma epinephrine oxidase activity". Trabalho apresentado em 6th Portuguese Congress on Free Radicals in Chemistry, Biology and Medicine 1st Luso-Spanish Congress on Free Radicals, 2003.
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2019/06/28 Lytr from streptococcus dysgalactiae subs. dysgalactiae: A target for biofilm inhibition 8th Meeting of Portuguese Synchrotron Radiation Users (ENURS 2019)
(Porto, Portugal)
2019/06/28 Arsenite oxidase: from the substrate analogue to the electron acceptors structural and function insights 8th Meeting of Portuguese Synchrotron Radiation Users (ENURS 2019)
(Porto, Portugal)
2015/06 Structural insights into a unique periplasmic aldehyde oxidoreductase from Escherichia coli 6th European Conference of Chemistry for Life Sciences
(Lisboa, Portugal)
2008 Identification of a novel family of Carbohydrate-Binding Domains that bind decorations of complex polysaccharides Congresso Nacional de Bioquímica
(Açores, Portugal)
2007/06/14 Aspectos funcionais e estruturais de uma nova familia de CBM’s Jornadas de pós-graduação da Faculdade de Medicina Veterinária da Universidade Técnica de Lisboa
Faculdade de Medicina Veterinária da Universidade Técnica de Lisboa (Lisboa, Portugal)
2004 Actividade do oxidase da adrenalina e o processo inflamatório na hipertensão arterial: Possível associação com o genótipo do GSTT1 1ª reunião da Sociedade Portuguesa de Hipertensão
(Porto)
2004 Genetic distribution of GSTM1 and GSTT1 in portuguese women with cervical cancer: association with plasma epinephrine oxidase activity III Simpósio Internacional HPV e Cancro
(Lisboa, Portugal)

Orientação

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2019/09/01 - 2020/09/01 Assessment of natural compounds as novel anti-diabetic drugs
Orientador de Filipa Lopes
 Bioquímica (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2018/09 - 2019/09 Bacterial arsenite oxidation at the molecular level
Coorientador de Filipa Sofia Silva Engrola
 Bioquímica (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2013/09 - 2014/09 Structural and Functional characterization of ModA and TupA proteins belonging to the molybdate and tungstate transport system from Desulfovibrio alaskensis G20
Orientador
 Bioquímica (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação) 		Instituição / Organização
2015/07/13 - 2015/07/19 Co-organizer and Speaker of ISBio2015: Course on Integrative Structural Biology - Integrative Structural Biology tools for the study of protein-ligand interactions, speaker on the Isothermal Titration Calorimetry (ITC) module lecture (2015/07/13 - 2015/07/19)
Oficina (workshop) (Coorganizador)
 REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2014/10/06 - 2014/10/12 Co-organizer and Speaker of ISBio2014: Course on Integrative Structural Biology - Integrative Structural Biology tools for the study of protein-ligand interactions, speaker on the Isothermal Titration Calorimetry (ITC) module lecture (2014/10/06 - 2014/10/12)
Oficina (workshop) (Coorganizador)
 REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal

Participação em evento

Descrição da atividade
Tipo de evento 		Nome do evento
Instituição / Organização
2019/05/26 - 2019/05/31 International School on Biological Crystallization
Oficina (workshop)
 International School on Biological Crystallization: ISBC 2019
Universidad de Granada, Espanha
2019/02/27 - 2019/02/28 BAG Training sessions for users of the Macromolecular Crystallography (MX) beamlines at the Diamond Light Source
Oficina (workshop)
 MX BAG Training 2019
Diamond Light Source Ltd, Reino Unido
2018/05 - 2018/05 BAG Training sessions for users of the Macromolecular Crystallography (MX) beamlines at the European Synchrotron Radiation Facility
Oficina (workshop)
 ESRF MX BAG Training 2018
ESRF, França
2013/05/06 - 2013/05/10 Course: Small angle neutron and X-ray scattering from proteins in solution
Oficina (workshop)
 EMBO Practical Course. Small angle neutron and X-ray scattering from proteins in solution
Institut Laue-Langevin, França
2013/01/03 - 2013/01/05 CCP4 Study Weekend 2013
Oficina (workshop)
 CCP4 Study Weekend
Nottingham Trent University, Reino Unido
2012/10/20 - 2012/10/27 The sixth BioCrys course 2012.
Oficina (workshop)
 BioCrys 2012
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2012 - 2012 BAG Training sessions for users of the Macromolecular Crystallography (MX) beamlines at the European Synchrotron Radiation Facility
Oficina (workshop)
 BAG Training 2012
ESRF, França
2007 - 2007 Protein Crystallography Course
Oficina (workshop)
 Protein Crystallography Course (Monographic Course 2007)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
Distinções

Prémio

2010 Post-doctoral Grant - reference FCT: SFRH/BPD/64917/2009
Fundação para a Ciência e a Tecnologia, I.P., Portugal
2006 PhD Research Grant - reference FCT: SFRH/BD/23784/2005
Fundação para a Ciência e a Tecnologia, I.P., Portugal