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I got Bachelor degree in Industrial Chemistry in 2012 and Master degree in Material Chemistry in 2014, at the University of Catania. In 2019 I obtained the PhD in Structural Biochemistry at Aix-Marseille Université – CEA Cadarache. I started my first PostDoc in the same year at the Instituto de Tecnologia Quìmica e Biològica (ITQB NOVA) in Lisbon. I am interested in studying structure-function relationship in metalloproteins in both natural and artificial processes. During my PhD I manly focused my interest in the manganese cofactor (OEC) involved in the conversion of water into oxygen as well as in ferredoxins and heme proteins implicated in electron-transfer processes during natural photosynthesis. I developed my expertise in FTIR spectroscopy, coupled with electrochemistry and photochemistry. Now, at ITQB I am further developing proficiency in vibrational spectroscopy, implementing my knowledges with RR spectroscopy and related techniques. I am currently working on endonucleases and dye-decolorizing peroxidases.
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Identificação

Identificação pessoal

Nome completo
Lidia Zuccarello

Nomes de citação

  • Zuccarello, Lidia

Identificadores de autor

Ciência ID
0C18-F7FE-BC84
ORCID iD
0000-0002-7201-1767

Endereços de correio eletrónico

  • lidiazuccarello@itqb.unl.pt (Profissional)

Domínios de atuação

  • Ciências Naturais - Ciências Biológicas

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Italiano (Idioma materno)
Inglês Utilizador independente (B2) Utilizador proficiente (C1) Utilizador independente (B2) Utilizador independente (B2)
Francês Utilizador independente (B2) Utilizador independente (B2) Utilizador independente (B1) Utilizador proficiente (C1)
Formação
Grau Classificação
2016/01 - 2019/04
Concluído
 Structural Biochemistry (Docteur)
Aix-Marseille Université, França
"Structure-function relationships of photosynthesis related proteins studied by Mid- and Far- FTIR difference spectroscopy" (TESE/DISSERTAÇÃO)
2012/09 - 2014/07
Concluído
 Material Chemistry (Laurea Magistrale)
Università degli Studi di Catania, Itália
"FRET and FRAP Confocal Laser Microscopy applications on hybrid nanomaterials study" (TESE/DISSERTAÇÃO)
2008/09 - 2012/07
Concluído
 Chimica Industriale (Bachelor)
Università degli Studi di Catania, Itália
"Synthesis of nanostructured materials with laser ablation of graphite in water" (TESE/DISSERTAÇÃO)
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2019/09 - Atual Pós-doutorado (Investigação) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2014 - 2015 Investigador (Investigação) Università degli Studi di Catania, Itália
Projetos

Bolsa

Designação Financiadores
2016/01 - 2019/04 PS2FIR ANR project
PS2FIR
Bolseiro de Doutoramento
Agence nationale de la recherche
Concluído

Projeto

Designação Financiadores
2019/09 - Atual Oxidoreductase-based electrochemical biosensors: rational design guided by biophysical characterization
PTDC/BIA-BFS/31026/2017
Investigador
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
 Associação para a Inovação e Desenvolvimento da FCT
Em curso
Produções

Publicações

Artigo em revista
  1. Caserta, Giorgio; Zuccarello, Lidia; Barbosa, Catarina; Silveira, Célia M.; Moe, Elin; Katz, Sagie; Hildebrandt, Peter; Zebger, Ingo; Todorovic, Smilja. "Unusual structures and unknown roles of FeS clusters in metalloenzymes seen from a resonance Raman spectroscopic perspective". Coordination Chemistry Reviews 452 (2021): 214287. http://dx.doi.org/10.1016/j.ccr.2021.214287.
    Aceite para publicação • 10.1016/j.ccr.2021.214287
  2. Célia M. Silveira; Lidia Zuccarello; Catarina Barbosa; Giorgio Caserta; Ingo Zebger; Peter Hildebrandt; Smilja Todorovic. "Molecular Details on Multiple Cofactor Containing Redox Metalloproteins Revealed by Infrared and Resonance Raman Spectroscopies". Molecules (2021): https://doi.org/10.3390/molecules26164852.
    10.3390/molecules26164852
  3. Lidia Zuccarello; Catarina Barbosa; Edilson Galdino; Nikola Loncar; Célia M. Silveira; Marco W. Fraaije; Smilja Todorovic. "SERR Spectroelectrochemistry as a Guide for Rational Design of DyP-Based Bioelectronics Devices". International Journal of Molecular Sciences 22 15 (2021): 7998-7998. https://doi.org/10.3390/ijms22157998.
    10.3390/ijms22157998
  4. Lidia Zuccarello; Catarina Barbosa; Smilja Todorovic; Célia M. Silveira. "Electrocatalysis by Heme Enzymes—Applications in Biosensing". Catalysts 11 2 (2021): 218-218. https://doi.org/10.3390/catal11020218.
    10.3390/catal11020218
  5. Zuccarello, Lidia. "Protonation of the Cysteine Axial Ligand Investigated in His/Cys c-type Cytochrome by UV-Vis, Mid- and Far-IR Spectroscopy". The Journal of Physical Chemistry Letters (2020): http://dx.doi.org/10.1021/acs.jpclett.0c01016.
    10.1021/acs.jpclett.0c01016
  6. Taiki Motomura; Lidia Zuccarello; Pierre Sétif; Alain Boussac; Yasufumi Umena; David Lemaire; Jatindra N. Tripathy; et al. "An alternative plant-like cyanobacterial ferredoxin with unprecedented structural and functional properties". Biochimica et Biophysica Acta (BBA) - Bioenergetics 1860 11 (2019): 148084-148084. https://doi.org/10.1016%2Fj.bbabio.2019.148084.
    10.1016/j.bbabio.2019.148084
  7. Patrizia Di Pietro; Gaetano Strano; Lidia Zuccarello; Cristina Satriano. "Gold and Silver Nanoparticles for Applications in Theranostics". Current Topics in Medicinal Chemistry 16 27 (2016): 3069-3102. https://doi.org/10.2174%2F1568026616666160715163346.
    10.2174/1568026616666160715163346
  8. L. Zuccarello; E. Rampazzo; L. Petrizza; L. Prodi; C. Satriano. "The influence of fluorescent silica nanoparticle surface chemistry on the energy transfer processes with lipid bilayers". RSC Advances 6 58 (2016): 52674-52682. https://doi.org/10.1039%2Fc6ra09816a.
    10.1039/c6ra09816a
Tese / Dissertação
  1. Zuccarello, Lidia. "Structure-function relationships of photosynthesis related proteins studied by Mid- and Far- FTIR difference spectroscopy". Doutoramento, Aix-Marseille Université, 2019.

Outros

Outra produção
  1. Investigation of Oxygen Evolving Complex catalytic cycle by Far-FTIR difference spectroscopy. Poster presentation at Congress SCF 18. 2018. Zuccarello, Lidia.
  2. Probing cysteine and water molecules in redox proteins by FTIR difference spectroscopy. Poster presentation at Journées franco-italiennes de chimie. 2018. Zuccarello, Lidia.
  3. Supported lipid bilayer-driven nanoparticle cellular uptake for theranostic applications. Poster presentation at E-MRS Spring Meeting. 2015. Zuccarello, Lidia.
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2019/08/14 Effect of cysteine axial ligation in c-type cytochromes with native His/Cys heme coordination studied by FTIR difference spectroscopy IC-BIC19
(Interlaken, Suiça)
2018/05/31 Photosynthesis related redox proteins studied by FTIR difference spectroscopy International Symposium of Quantum Beam Science in Biology and Soft Matter
(Mito, Japão)
2018/04/05 Investigation of Oxygen Evolving Complex catalytic cycle by Far FTIR difference spectroscopy Journées de la phoyosynthèse
ScPhi (Paris, França)
2017/12/08 Metal-ligand properties in new cytochromes and ferredoxins of T. elongatus • France-Japan Joint Workshop on Photosysthem II
Matsuyama University (Matsuyama, Japão)
Distinções

Prémio

2018 Best Oral Presentation
Société Française de Photosynthèse, França