| Artigo em revista |
- Dias, Cândida; Fernandes, Eliana; Barbosa, Rui M.; Laranjinha, João; Ledo, Ana. Autor correspondente: Ledo, Ana. "Astrocytic
aerobic glycolysis provides lactate to support neuronal oxidative metabolism in the hippocampus". BioFactors 49 4 (2023):
875-886. http://dx.doi.org/10.1002/biof.1951.
Publicado • 10.1002/biof.1951
- C. Dias; C.F. Lourenço; J. Laranjinha; Ana Ledo. "Modulation of oxidative neurometabolism in ischemia/reperfusion by nitrite".
Free Radical Biology and Medicine 193 (2022): 779-786. http://dx.doi.org/10.1016/j.freeradbiomed.2022.11.021.
10.1016/j.freeradbiomed.2022.11.021
- Dias, Cândida; Fernandes, Eliana; Barbosa, Rui M.; Ledo, Ana. Autor correspondente: Ledo, Ana. "A Platinized Carbon Fiber
Microelectrode-Based Oxidase Biosensor for Amperometric Monitoring of Lactate in Brain Slices". Sensors 22 18 (2022):
7011. http://dx.doi.org/10.3390/s22187011.
Publicado • 10.3390/s22187011
- Mancini, Gianni; Dias, Cândida; Lourenço, Cátia F.; Laranjinha, João; de Bem, Andreza; Ledo, Ana. "A High Fat/Cholesterol
Diet Recapitulates Some Alzheimer's Disease-Like Features in Mice: Focus on Hippocampal Mitochondrial Dysfunction". Journal
of Alzheimer's Disease 82 4 (2021): 1619-1633. http://dx.doi.org/10.3233/jad-210122.
10.3233/jad-210122
- Monteiro, Tiago; Dias, Cândida; Lourenço, Cátia F.; Ledo, Ana; Barbosa, Rui M.; Almeida, M. Gabriela. "Microelectrode Sensor
for Real-Time Measurements of Nitrite in the Living Brain, in the Presence of Ascorbate". Biosensors 11 8 (2021): 277.
http://dx.doi.org/10.3390/bios11080277.
Acesso aberto • 10.3390/bios11080277
- Rodrigues, Matilde S.; Ferreira, Cláudia; Dias, Cândida; Pliássova, Anna; Souza, Lisiane; Ledo, Ana; Laranjinha, João; Cunha,
Rodrigo A.; Köfalvi, Attila. "An optimized spectrophotometric assay reveals increased activity of enzymes involved in 2-arachidonoyl
glycerol turnover in the cerebral cortex of a rat model of Alzheimer's disease". European Journal of Neuroscience (2020):
http://dx.doi.org/10.1111/ejn.14944.
10.1111/ejn.14944
- Dias, Cândida; Lourenço, Cátia F.; Barbosa, Rui M.; Laranjinha, João; Ledo, Ana. "Analysis of respiratory capacity in brain
tissue preparations: high-resolution respirometry for intact hippocampal slices". Analytical Biochemistry 551 (2018):
43-50. https://doi.org/10.1016/j.ab.2018.05.010.
10.1016/j.ab.2018.05.010
- Dias, Cândida; Lourenço, Cátia F.; Ferreiro, Elisabete; Barbosa, Rui M.; Laranjinha, João; Ledo, Ana. "Age-dependent changes
in the glutamate-nitric oxide pathway in the hippocampus of the triple transgenic model of Alzheimer's disease: implications
for neurometabolic regulation". Neurobiology of Aging 46 (2016): 84-95. https://doi.org/10.1016%2Fj.neurobiolaging.2016.06.012.
10.1016/j.neurobiolaging.2016.06.012
- Lourenço, Cátia F.; Ledo, Ana; Dias, Cândida; Barbosa, Rui M.; Laranjinha, João. "Neurovascular and neurometabolic derailment
in aging and Alzheimer's disease". Frontiers in Aging Neuroscience 7 (2015): https://doi.org/10.3389%2Ffnagi.2015.00103.
10.3389/fnagi.2015.00103
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| Resumo em conferência |
- Dias, Cândida; Lourenço, Cátia F.; Barbosa, Rui M.; Laranjinha, João; Ledo, Ana. "Nitrite modulates mitochondrial respiration
in brain ischemia/reperfusion.". Trabalho apresentado em Annual Meeting of the Society-for-Free-Radical-Research- Europe
(SFRRE) on Redox Homeostasis - From Signaling to Damage, Ferrara, 2019.
- Ledo, Ana; Dias, Cândida; Lourenço, Cátia F.; Barbosa, Rui M.; Laranjinha, João. "Nitric oxide bioactivity in the brain -
aging and disease.". Trabalho apresentado em Annual Meeting of the Society-for-Free-Radical-Research- Europe (SFRRE) on
Redox Homeostasis - From Signaling to Damage, Ferrara, 2019.
Publicado
- Laranjinha, João; Lourenço, Cátia F.; Ledo, Ana; Dias, Cândida; Ferreira, Nuno Ricardo Esteves; Barbosa, Rui M.. "Redox regulation
of neurovascular-neuroenergetic coupling axis by nitric oxide in animal models of aging and neurodegeneration". Trabalho apresentado
em EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, Coimbra, 2019.
Publicado
- Ledo, Ana; Mancini, Gianni; Dias, Cândida; Lourenço, Cátia F.; Laranjinha, João; de Bem, Andreza. "Connecting the dots between
a High-Fat/Cholesterol Diet and Sporadic Alzheimer's Disease". Trabalho apresentado em EUROPEAN JOURNAL OF CLINICAL INVESTIGATION,
Coi8mbra, 2019.
Publicado
- Ledo, Ana; Dias, Cândida; Lourenço, Cátia F.; Barbosa, Rui M.; Laranjinha, João. "Nitric oxide bioactivity in the hippocampus
in aging and neurodegeneration". Trabalho apresentado em EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, Coimbra,
2019.
Publicado
- Mancini, Gianni; Dias, Cândida; Lourenço, Cátia F.; Barbosa, Rui M.; Laranjinha, João; de Bem, Andreza F.; Ledo, Ana. "High-fat
and high cholesterol diet induces Alzheimer's like disease in mice". Trabalho apresentado em 19th Biennial Meeting of the
Society-for-Free-Radical-Research-International (SFRRI), Lisboa, 2018.
Publicado
- Dias, Cândida; Lourenço, Cátia F.; Barbosa, Rui M.; Laranjinha, João; Ledo, Ana. "Age-dependent impairment of the glutamate-nitric
oxide pathway in the hippocampus of the triple transgenic mouse model of Alzheimer's disease". Trabalho apresentado em 19th
Biennial Meeting of the Society-for-Free-Radical-Research-International (SFRRI), Lisboa, 2018.
Publicado • 10.1016/j.freeradbiomed.2018.04.459
- Dias, Cândida; Ferreira, Nuno Ricardo Esteves; Ledo, Ana; Barbosa, Rui M.; Laranjinha, J.. "The interplay of nitrite:ascorbate:nitric
oxide and its contribution to neurovascular coupling in the hippocampus". Trabalho apresentado em 19th Biennial Meeting
of the Society-for-Free-Radical-Research-International (SFRRI), Lisboa, 2018.
Publicado • 10.1016/j.freeradbiomed.2018.04.469
- Monteiro, Tiago; Dias, Cândida; Lourenço, Cátia F.; Ledo, Ana; Laranjinha, João; Barbosa, Rui M.; Almeida, Maria G.. "Real-time
detection of nitrite in the brain using carbon fibre microelectrodes". Trabalho apresentado em 2nd International Congress
of CiiEM - Translational Research and Innovation in Human and Health Sciences, Almada, 2018.
Publicado
- Dias, Cândida; Monteiro, Tiago; Lourenço, Cátia F.; Ledo, Ana; Almeida, Maria G.; Laranjinha, João; Barbosa, Rui M.. "Probing
nitrite and nitric oxide biochemistry in the brain in vivo by a novel sensing approach". Trabalho apresentado em ISN-ESN
Meeting, Paris, 2017.
Publicado
- Laranjinha, João; Lourenço, Cátia F.; Ledo, Ana; Dias, Cândida; Ferreira, Nuno Ricardo Esteves; Barbosa, Rui M.. "Regulation
of neurovascular coupling in the brain by nitrite". Trabalho apresentado em OCC World Congress / Annual SFRR-E Conference,
Berlim, 2017.
Publicado • 10.1016/j.freeradbiomed.2017.04.065
- Dias C; Barbosa RM; Laranjinha J; Ledo A. "Evaluation of Mitochondrial Function in the CNS of Rodent Models of Alzheimer's
Disease - High Resolution Respirometry Applied to Acute Hippocampal Slices.". 2014.
10.1016/j.freeradbiomed.2014.10.780
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