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Cândida Marília das Neves Dias. Concluiu o Mestrado em Bioquímica em 2012/07 pela Universidade de Aveiro e Licenciatura em Bioquímica em 2010/07 pela Faculdade de Ciências e Tecnologia da Universidade de Coimbra. Concluiu o Doutoramento em Ciências Farmacêuticas pela Faculdade de Farmácia da Universidade de Coimbra em 2022/09. Publicou 5 artigos originais em revistas especializadas e é co-autora em 4 artigos. Participou em 3 congressos internacionais e 3 nacionais. Recebeu 2 prémios de melhor poster. Participou em 3 cursos/workshops internacionais.
Identification

Personal identification

Full name
Cândida Marília das Neves Dias

Citation names

  • Dias, Cândida

Author identifiers

Ciência ID
031F-6516-FBF2
ORCID iD
0000-0003-4744-9254

Languages

Language Speaking Reading Writing Listening Peer-review
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Outputs

Publications

Conference abstract
  1. Dias, Cândida; Lourenço, Cátia F.; Barbosa, Rui M.; Laranjinha, João; Ledo, Ana. "Nitrite modulates mitochondrial respiration in brain ischemia/reperfusion.". Paper presented in Annual Meeting of the Society-for-Free-Radical-Research- Europe (SFRRE) on Redox Homeostasis - From Signaling to Damage, Ferrara, 2019.
  2. Ledo, Ana; Dias, Cândida; Lourenço, Cátia F.; Barbosa, Rui M.; Laranjinha, João. "Nitric oxide bioactivity in the brain - aging and disease.". Paper presented in Annual Meeting of the Society-for-Free-Radical-Research- Europe (SFRRE) on Redox Homeostasis - From Signaling to Damage, Ferrara, 2019.
    Published
  3. Laranjinha, João; Lourenço, Cátia F.; Ledo, Ana; Dias, Cândida; Ferreira, Nuno Ricardo Esteves; Barbosa, Rui M.. "Redox regulation of neurovascular-neuroenergetic coupling axis by nitric oxide in animal models of aging and neurodegeneration". Paper presented in EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, Coimbra, 2019.
    Published
  4. Ledo, Ana; Mancini, Gianni; Dias, Cândida; Lourenço, Cátia F.; Laranjinha, João; de Bem, Andreza. "Connecting the dots between a High-Fat/Cholesterol Diet and Sporadic Alzheimer's Disease". Paper presented in EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, Coi8mbra, 2019.
    Published
  5. Ledo, Ana; Dias, Cândida; Lourenço, Cátia F.; Barbosa, Rui M.; Laranjinha, João. "Nitric oxide bioactivity in the hippocampus in aging and neurodegeneration". Paper presented in EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, Coimbra, 2019.
    Published
  6. Mancini, Gianni; Dias, Cândida; Lourenço, Cátia F.; Barbosa, Rui M.; Laranjinha, João; de Bem, Andreza F.; Ledo, Ana. "High-fat and high cholesterol diet induces Alzheimer's like disease in mice". Paper presented in 19th Biennial Meeting of the Society-for-Free-Radical-Research-International (SFRRI), Lisboa, 2018.
    Published
  7. Dias, Cândida; Lourenço, Cátia F.; Barbosa, Rui M.; Laranjinha, João; Ledo, Ana. "Age-dependent impairment of the glutamate-nitric oxide pathway in the hippocampus of the triple transgenic mouse model of Alzheimer's disease". Paper presented in 19th Biennial Meeting of the Society-for-Free-Radical-Research-International (SFRRI), Lisboa, 2018.
    Published • 10.1016/j.freeradbiomed.2018.04.459
  8. Dias, Cândida; Ferreira, Nuno Ricardo Esteves; Ledo, Ana; Barbosa, Rui M.; Laranjinha, J.. "The interplay of nitrite:ascorbate:nitric oxide and its contribution to neurovascular coupling in the hippocampus". Paper presented in 19th Biennial Meeting of the Society-for-Free-Radical-Research-International (SFRRI), Lisboa, 2018.
    Published • 10.1016/j.freeradbiomed.2018.04.469
  9. Monteiro, Tiago; Dias, Cândida; Lourenço, Cátia F.; Ledo, Ana; Laranjinha, João; Barbosa, Rui M.; Almeida, Maria G.. "Real-time detection of nitrite in the brain using carbon fibre microelectrodes". Paper presented in 2nd International Congress of CiiEM - Translational Research and Innovation in Human and Health Sciences, Almada, 2018.
    Published
  10. Dias, Cândida; Monteiro, Tiago; Lourenço, Cátia F.; Ledo, Ana; Almeida, Maria G.; Laranjinha, João; Barbosa, Rui M.. "Probing nitrite and nitric oxide biochemistry in the brain in vivo by a novel sensing approach". Paper presented in ISN-ESN Meeting, Paris, 2017.
    Published
  11. Laranjinha, João; Lourenço, Cátia F.; Ledo, Ana; Dias, Cândida; Ferreira, Nuno Ricardo Esteves; Barbosa, Rui M.. "Regulation of neurovascular coupling in the brain by nitrite". Paper presented in OCC World Congress / Annual SFRR-E Conference, Berlim, 2017.
    Published • 10.1016/j.freeradbiomed.2017.04.065
  12. Dias C; Barbosa RM; Laranjinha J; Ledo A. "Evaluation of Mitochondrial Function in the CNS of Rodent Models of Alzheimer's Disease - High Resolution Respirometry Applied to Acute Hippocampal Slices.". 2014.
    10.1016/j.freeradbiomed.2014.10.780
Journal article
  1. Dias, Cândida; Fernandes, Eliana; Barbosa, Rui M.; Laranjinha, João; Ledo, Ana. Corresponding author: Ledo, Ana. "Astrocytic aerobic glycolysis provides lactate to support neuronal oxidative metabolism in the hippocampus". BioFactors 49 4 (2023): 875-886. http://dx.doi.org/10.1002/biof.1951.
    Published • 10.1002/biof.1951
  2. C. Dias; C.F. Lourenço; J. Laranjinha; Ana Ledo. "Modulation of oxidative neurometabolism in ischemia/reperfusion by nitrite". Free Radical Biology and Medicine 193 (2022): 779-786. http://dx.doi.org/10.1016/j.freeradbiomed.2022.11.021.
    10.1016/j.freeradbiomed.2022.11.021
  3. Dias, Cândida; Fernandes, Eliana; Barbosa, Rui M.; Ledo, Ana. Corresponding author: Ledo, Ana. "A Platinized Carbon Fiber Microelectrode-Based Oxidase Biosensor for Amperometric Monitoring of Lactate in Brain Slices". Sensors 22 18 (2022): 7011. http://dx.doi.org/10.3390/s22187011.
    Published • 10.3390/s22187011
  4. Mancini, Gianni; Dias, Cândida; Lourenço, Cátia F.; Laranjinha, João; de Bem, Andreza; Ledo, Ana. "A High Fat/Cholesterol Diet Recapitulates Some Alzheimer's Disease-Like Features in Mice: Focus on Hippocampal Mitochondrial Dysfunction". Journal of Alzheimer's Disease 82 4 (2021): 1619-1633. http://dx.doi.org/10.3233/jad-210122.
    10.3233/jad-210122
  5. Monteiro, Tiago; Dias, Cândida; Lourenço, Cátia F.; Ledo, Ana; Barbosa, Rui M.; Almeida, M. Gabriela. "Microelectrode Sensor for Real-Time Measurements of Nitrite in the Living Brain, in the Presence of Ascorbate". Biosensors 11 8 (2021): 277. http://dx.doi.org/10.3390/bios11080277.
    Open access • 10.3390/bios11080277
  6. Rodrigues, Matilde S.; Ferreira, Cláudia; Dias, Cândida; Pliássova, Anna; Souza, Lisiane; Ledo, Ana; Laranjinha, João; Cunha, Rodrigo A.; Köfalvi, Attila. "An optimized spectrophotometric assay reveals increased activity of enzymes involved in 2-arachidonoyl glycerol turnover in the cerebral cortex of a rat model of Alzheimer's disease". European Journal of Neuroscience (2020): http://dx.doi.org/10.1111/ejn.14944.
    10.1111/ejn.14944
  7. Dias, Cândida; Lourenço, Cátia F.; Barbosa, Rui M.; Laranjinha, João; Ledo, Ana. "Analysis of respiratory capacity in brain tissue preparations: high-resolution respirometry for intact hippocampal slices". Analytical Biochemistry 551 (2018): 43-50. https://doi.org/10.1016/j.ab.2018.05.010.
    10.1016/j.ab.2018.05.010
  8. Dias, Cândida; Lourenço, Cátia F.; Ferreiro, Elisabete; Barbosa, Rui M.; Laranjinha, João; Ledo, Ana. "Age-dependent changes in the glutamate-nitric oxide pathway in the hippocampus of the triple transgenic model of Alzheimer's disease: implications for neurometabolic regulation". Neurobiology of Aging 46 (2016): 84-95. https://doi.org/10.1016%2Fj.neurobiolaging.2016.06.012.
    10.1016/j.neurobiolaging.2016.06.012
  9. Lourenço, Cátia F.; Ledo, Ana; Dias, Cândida; Barbosa, Rui M.; Laranjinha, João. "Neurovascular and neurometabolic derailment in aging and Alzheimer's disease". Frontiers in Aging Neuroscience 7 (2015): https://doi.org/10.3389%2Ffnagi.2015.00103.
    10.3389/fnagi.2015.00103