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Julio Cesar Machado Junior. Graduated in pharmacy and biochemistry with a master's degree in Pharmaceutical Sciences (Faculty of Pharmacy, UFPR, Brazil), and PhD in Pharmaceutical Sciences with a specialization in Nutrition and Food Chemistry at the Faculty of Pharmacy, University of Porto (Portugal).
Identification

Personal identification

Full name
Júlio César Machado Júnior

Citation names

  • Machado Jr, Julio C.

Author identifiers

Ciência ID
FC12-0434-6878
ORCID iD
0000-0002-9366-5591

Email addresses

  • jcmjunior@ff.up.pt (Professional)
  • juliocesarmachadojunior@gmail.com (Personal)

Telephones

Mobile phone
  • 925162878 (Personal)

Knowledge fields

  • Medical and Health Sciences - Basic Medicine - Pharmacology and pharmacy
  • Medical and Health Sciences - Basic Medicine - Pharmacology and pharmacy
  • Medical and Health Sciences - Basic Medicine - Pharmacology and pharmacy

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Intermediate (B1) Upper intermediate (B2) Intermediate (B1) Intermediate (B1) Intermediate (B1)
Education
Degree Classification
2015/09 - 2019/09
Concluded
Pharmaceutical Science (Doutoramento)
Major in Specialty: Nutrition and Food Chemistry
Universidade do Porto Faculdade de Farmácia, Portugal
"Chemical, biological and sensory characterization of hops and dry-hopped beers: Perspectives for use of Portuguese genotypes" (THESIS/DISSERTATION)
Aprovado
2018 - 2018
Concluded
Moodle for teachers and educators (Outros)
Evolui.com, Portugal
2018 - 2018
Concluded
Sensory practice for beer and beer-based beverages (Outros)
Lehrstuhl für Brau- und Getränketechnologie, Weihenstephan, TUM, Germany
2016/01/25 - 2016/03/11
Concluded
Sensory control (Outros)
Universidade do Porto Faculdade de Farmácia, Portugal
2013 - 2013
Concluded
Empretec (Outros)
Sebrae - Serviço de Apoio às Micro e Pequenas Empresas, Brazil

Organização das Nações Unidas, Brazil
2013 - 2013
Concluded
Beer technology and practice (Outros)
Centro de Tecnologia SENAI - Alimentos e Bebidas, Brazil
2012 - 2012
Concluded
Financial management (Outros)
Sebrae - Serviço de Apoio às Micro e Pequenas Empresas, Brazil
2010 - 2010
Concluded
Beer sommelier (Outros)
Instituto de Cerveja do Brasil, Brazil

Associação Brasileira de Sommeliers, Brazil
2003/03/01 - 2005/05/30
Concluded
Mestrado em Ciências Farmacêuticas (Master)
Universidade Federal do Paraná, Brazil
"Study in vitro of the immunomodulatory potential of medicinal plants by flow cytometry" (THESIS/DISSERTATION)
1993/03/01 - 1998/07/27
Concluded
Pharmacist and Biochemist (Graduado)
Universidade do Vale do Itajaí, Brazil
Affiliation

Science

Category
Host institution
Employer
2025/02/01 - Current Auxiliary Researcher (Research) CFER Center for Food Education and Research, Portugal
CFER Center for Food Education and Research, Portugal
2019/09/29 - 2023/09/30 Researcher (Research) Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal
Universidade do Porto Faculdade de Farmácia, Portugal
2013/04/24 - 2014 Researcher (Research) Instituto de Pesquisa Treinamentos e Eventos da Cerveja, Brazil

Teaching in Higher Education

Category
Host institution
Employer
2023/10/01 - 2024/08/31 Invited Assistant (University Teacher) Universidade do Porto Faculdade de Farmácia, Portugal
Universidade do Porto Faculdade de Farmácia, Portugal

Others

Category
Host institution
Employer
2015/05/13 - 2016/02/12 Managing partner Laboratório do Saber, Brazil
2012/11/22 - 2015/05 Managing partner Catarina Importadora de Cervejas, Brazil
2013/03/01 - 2013/11/07 Maneger/ Beer sommelier Bar e Restaurante Bier Vila, Brazil
2010/07/05 - 2013/02 Managing partner Empório São Patrício - Loja e Bar de Cervejas Artesanais, Brazil
2012/03/01 - 2012/09 Managing partner VKM Bebidas, Brazil
2005/01/27 - 2011/03/03 Pharmacist Biochemist Centro de Hematologia Hemoterapia do Paraná (HEMEPAR), Brazil
2001/05/02 - 2003/03/05 Pharmacist Biochemist Laboratório Álvaro de Análises Clínicas, Brazil
1999/02/01 - 1999/07/01 Pharmacist Biochemist Laboratório Equipe de Análises Clínicas, Brazil
1998/09/02 - 1999/01/31 Pharmacist Biochemist Universidade do Vale do Itajaí, Brazil
1998 - 1999 Pharmacist Farmácia Biovita, Brazil
1998/07/15 - 1998/09/01 Pharmacist Biochemist Fundação Extensão e Pesquisa Educacionais (FUNDEPE), Brazil
Universidade do Vale do Itajaí, Brazil
Projects

Grant

Designation Funders
2020/09 - 2023/03 Innovative and sustainable technologies in the valuation of agro-industrial by-products to obtain new food ingredients with bioactive properties
UIDB/00211/2020
Research Fellow
Universidade do Porto Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares, Portugal

Universidade do Porto Centro de Estudos de Ciencia Animal, Portugal
Fundação para a Ciência e a Tecnologia

Governo da República Portuguesa Ministério da Ciência Tecnologia e Ensino Superior
Ongoing
2019/10 - 2020/03 Preparation and evaluation of the bioactive properties of enriched low alcoholic beers.
UID/QUI/50006/2019
Research Fellow
REQUIMTE LAQV Porto, Portugal

Universidade do Porto Faculdade de Farmácia, Portugal
Associação para a Inovação e Desenvolvimento da FCT
2016/05/16 - 2018/11 Development of analytical methodologies by chromatographic methods to study hops compounds and analyze the impact on beer
Research Fellow
Universidade do Porto Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares, Portugal

Universidade do Porto Faculdade de Farmácia, Portugal
Associação para a Inovação e Desenvolvimento da FCT
Concluded
2013/05 - 2014/08 Formation of a sensory panel to assess the quality of beer produced in Santa Catarina's microbreweries
Other
Universidade do Vale do Itajaí, Brazil

Instituto de Pesquisa Treinamentos e Eventos da Cerveja, Brazil
Governo de Santa Catarina

Universidade do Vale do Itajaí
Concluded

Contract

Designation Funders
2019/01/01 - 2019/12/31 Associated Laboratory for Green Chemistry - Clean Technologies and Processes
UID/QUI/50006/2019
Universidade do Porto Faculdade de Ciências, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal

Associação para a Inovação e Desenvolvimento da FCT, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2019/05 - 2019/11 Incorporation of elderberry for production of beer enriched with anthocyanins to increase bioactivity
NORTE-01-0246-FEDER-000043
Researcher
Universidade do Porto Faculdade de Farmácia, Portugal
European Regional Development Fund
Concluded
Outputs

Publications

Book chapter
  1. Zita E. Martins; Marta Silva; Júlio C. Machado; Isabel M. P. L. V. O. Ferreira. "Foods for Diet-related Disease Prevention and Health Promotion: Sensory Quality and Consumer Acceptance". 2024.
    10.1039/bk9781839166655-00488
  2. Junior, Julio. "Hops: New Perspectives for an Old Beer Ingredient". 2019.
    10.1016/b978-0-12-816689-5.00010-9
Conference poster
  1. Machado Jr, Julio C.; Ferreira, Isabel MPLVO. "Hops Predictor: artificial intelligence able to predict the aromatic impact of different hop varieties in beers". Paper presented in 39th Congress EBC European Brewery Convention, 2024.
  2. Ana Beatriz P. Teixeira; Diogo Figueira; Isabel M.P.L.V.O. Ferreira. "Hops as a promising clean-label preservative in food". Paper presented in Dare2Change, 2023.
  3. Pedro Nicola; Cunha, Sara C.; Viegas, Olga; Miguel A. Faria; Isabel M.P.L.V.O. Ferreira. "Impact of wood origin on the phenolic and volatile profile of beers obtained from different malts". Paper presented in 38th Congress EBC European Brewery Convention, 2022.
  4. Miguel A. Faria; Pedro D. M. Nicola; Viegas, Olga; Isabel M.P.L.V.O. Ferreira. Corresponding author: Miguel A. Faria. "Influence of malt type and wood origin on the bioactive properties of beers". Paper presented in 38th Congress EBC European Brewery Convention, 2022.
  5. Machado Jr, Julio C.; Carvalho, Celso D.; Melo, Armindo; Faria, Miguel; Cancela, Miguel; Martins, Zita E.; Silva, Cristina; Ferreira, Isabel MPLVO. "Consumer's acceptance of beers enriched with elderberry berries (Sambucus nigra)". Paper presented in Dare2Change, 2021.
  6. Junior, Julio; Miguel A. Faria; Ana Maria Barata; Andreja Cerenak; Isabel M.P.L.V.O. Ferreira. "Portuguese wild hops genotyping by HRMA of a minimal SNP set". Paper presented in 37th Congress EBC European Brewery Convention, 2019.
  7. Machado Jr, Julio C.; Miguel A. Faria; Armindo Melo; Isabel M.P.L.V.O. Ferreira. "Evaluation of a-acids content of beer produced by dry hopping techniques.". Paper presented in 36th Congress EBC European Brewery Convention, 2017.
  8. Miguel A. Faria; Machado Jr, Julio C.; Armindo Melo; Isabel M.P.L.V.O. Ferreira. "Antiproliferative activity of hop-derived compounds against human colon cancer Caco-2 cells". Paper presented in 36th Congress EBC European Brewery Convention, 2017.
  9. Armindo Melo; Machado Jr, Julio C.; Miguel A. Faria; C. Mansilha; Isabel M.P.L.V.O. Ferreira. "Impact of dry hopping techniques on xanthohumol content of beer.". Paper presented in 36th Congress EBC European Brewery Convention, 2017.
  10. Melo, Armindo; Machado Jr, Julio C.; Faria, MA; Mansilha, Catarina; Ferreira, Isabel MPLVO. "Impact of dry hopping techiques on xanthohumol contente of beer". Paper presented in 36th Congress EBC European Brewery Convention, 2017.
  11. Armindo Melo; Machado Jr, Julio C.; Ana A. Capitão; Miguel Cancela; Ana I. Ribeiro; C. Mansilha; Isabel M.P.L.V.O. Ferreira. "Xanthohumol evaluation in hop gun dry hopping techniques". Paper presented in 2nd International Conference on Food Chemistry and Technology, 2016.
  12. Melo, Armindo; Machado Jr, Julio C.; Capitão, A.A.; Cancela, M.; Ribeiro, A.I.; Mansilha, Catarina; Ferreira, Isabel MPLVO. "Xanthomol evaluation in hop gun dry hopping techniques". Paper presented in 2nd International Conference on Food Chemistry and Technology, 2016.
  13. Machado Jr, Julio C.; Cunha, S. C; Morais, J. S.; Isabel M.P.L.V.O. Ferreira. "Volatile profile of wild hops grown in the North of Portugal: Comparison with a cultivar hop produced in the same region.". Paper presented in FOODINTEGRITY 2016, Praga. Assuring the integrity of the food chain: Fighting Food Fraud., 2016.
  14. Machado Jr, Julio C.; Almeriane Maria Weffort Santos; Ângela Florão; Rocha, F. H.. "Medicinal Plants-Mediated Immunomodulation.". Paper presented in 5th International Congress of Pharmaceutical Sciences, 2005.
  15. Machado Jr, Julio C.; Julio Cesar Schuhmacher; Maique Weber Biavati. "Estudo experimental do efeito cicatrizante da cebola (Allium cepa L., Liliaceae) no tratamento de feridas da pele de cobaias.". Paper presented in XII Reunião Anual da Federação de Sociedades de Biologia Experimental, 1997.
Journal article
  1. Julio C. Machado, Jr.; Pedro D. M. Nicola; Olga Viegas; Mickael C. Santos; Miguel A. Faria; Isabel M. P. L. V. O. Ferreira. "Bioactive Properties and Phenolic Composition of Wood-Aged Beers: Influence of Oak Origin and the Use of Pale and Dark Malts". Foods (2023): https://doi.org/10.3390/foods12061237.
    10.3390/foods12061237
  2. Júlio C. Machado, Jr.; Zita E. Martins; Isabel M.P.L.V.O. Ferreira. "Dynamic sensory analysis by Temporal Dominance of Sensations paired with dynamic liking and wanting methodologies to understand the consumers’ preference between two beer styles enriched with elderberries". LWT (2023): https://doi.org/10.1016/j.lwt.2022.114266.
    10.1016/j.lwt.2022.114266
  3. Machado Jr, Julio C.. "Portuguese wild hop diversity assessment by fast SNP genotyping using high-resolution melting". Journal of Applied Genetics (2021): http://dx.doi.org/10.1007/s13353-021-00668-7.
    10.1007/s13353-021-00668-7
  4. Machado Jr, Julio C.. "Sensory and Olfactometry Chemometrics as Valuable Tools for Assessing Hops’ Aroma Impact on Dry-Hopped Beers: A Study with Wild Portuguese Genotypes". Foods 10 6 (2021): 1397-1397. http://dx.doi.org/10.3390/foods10061397.
    10.3390/foods10061397
  5. Machado Jr, Julio C.. "Prediction of fruity-citrus intensity of beers dry-hopped with Mandarina Bavaria based on the content of selected volatile compounds". Journal of Agricultural and Food Chemistry (2020): http://dx.doi.org/10.1021/acs.jafc.9b06139.
    10.1021/acs.jafc.9b06139
  6. Machado Jr, Julio C.. "A chemometric approach to compare Portuguese native hops with worldwide commercial varieties". Journal of Chemometrics 34 9 (2020): e3285-e3285. https://onlinelibrary.wiley.com/doi/abs/10.1002/cem.3285.
    https://doi.org/10.1002/cem.3285
  7. Machado, J.C.; Faria, M.A.; Melo, A.; Martins, Z.E.; Ferreira, I.M.P.L.V.O.. "Modeling of a-acids and xanthohumol extraction in dry-hopped beers". Food Chemistry 278 (2019): 216-222. http://www.scopus.com/inward/record.url?eid=2-s2.0-85056729343&partnerID=MN8TOARS.
    10.1016/j.foodchem.2018.11.050
  8. Machado, J.C.; Faria, M.A.; Ferreira, I.M.P.L.V.O.; Páscoa, R.N.M.J.; Lopes, J.A.. "Varietal discrimination of hop pellets by near and mid infrared spectroscopy". Talanta 180 (2018): 69-75. http://www.scopus.com/inward/record.url?eid=2-s2.0-85038213114&partnerID=MN8TOARS.
    10.1016/j.talanta.2017.12.030
  9. Machado, J.C.; Faria, M.A.; Melo, A.; Ferreira, I.M.P.L.V.O.. "Antiproliferative effect of beer and hop compounds against human colorectal adenocarcinome Caco-2 cells". Journal of Functional Foods 36 (2017): 255-261. http://www.scopus.com/inward/record.url?eid=2-s2.0-85023620264&partnerID=MN8TOARS.
    10.1016/j.jff.2017.07.006
  10. Nardin, J.M.; Lima, M.P.; MacHado, J.C.; Hilst, L.F.; De Moraes Santos, C.A.; Weffort-Santos, A.M.. "The uleine-rich fraction of himatanthus lancifolius blocks proliferative responses of human lymphoid cells". Planta Medica 76 7 (2010): 697-700. http://www.scopus.com/inward/record.url?eid=2-s2.0-77952037605&partnerID=MN8TOARS.
    10.1055/s-0029-1240648
  11. Florão, A.; Mattana, F.V.R.; Rocha, F.H.; Nardin, J.N.; Machado Jr., J.C.; Weffort-Santos, A.M.. "In vitro investigation of dimethylsulfoxide upon human lymphocyte proliferation,Efeitos do dimetilsulfóxido sobre a proliferação de linfócitos humanos in vitro". Latin American Journal of Pharmacy 26 2 (2007): 215-223. http://www.scopus.com/inward/record.url?eid=2-s2.0-34547570277&partnerID=MN8TOARS.
  12. Junior, Julio. "A citometria de fluxo como instrumento de avaliação da atividade imunomodulatória de extratos e substâncias isoladas de plantas medicinais". Revista Brasileira de Farmacognosia (2006): http://dx.doi.org/10.1590/s0102-695x2006000500011.
    10.1590/s0102-695x2006000500011
Magazine article
  1. Machado Jr, Julio C.; Martins, Zita E.; Miguel A. Faria; Isabel M.P.L.V.O. Ferreira. "Dinâmica Temporal de Sensações na análise sensorial de cervejas artesanais", TecnoAlimentar, 2021, http://www.tecnoalimentar.pt/noticias/dinamica-temporal-de-sensacoes-na-analise-sensorial-de-cervejas-artesanais/.
Website
  1. Machado Jr, Julio C.. Mochilão Cervejeiro. 2020. https://mochilaocervejeiro.pt/.
  2. Machado Jr, Julio C.. Beer-Learning. 2018. https://beer-learning.com/.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2024/11/15 Lúpulos e Análise Sensorial CONIB - Congresso Internacional da Cerveja
Governo do Estado da Bahia (Alagoinhas, Brazil)
2023/11/18 Lúpulos em Portugal: características, potencial e realidade Bahia Beer
Governo do Estado da Bahia (Alagoinhas, Brazil)
2019/07/18 Native Portuguese hops: new perspectives for craft beer. II Jornadas do Lúpulo e da Cerveja
IPB Bragança (Bragança, Portugal)
2019/07/18 Development of new beers: chemical and sensory analysis focused on the compounds and attributes of hops. II Jornadas do Lúpulo e da Cerveja
IPB Bragança (Bragança, Portugal)
2019/06/05 Characterizing the diversity of wild hops (Humulus lupulus) from Portugal. 37th Congress EBC European Brewery Convention
European Brewery Convention (Antuérpia, Belgium)
2019/05/21 Food aroma: beer. Pint of Science Portugal
Pint of Science (Bragança, Portugal)
2018/11/22 Correlation of aroma characteristics with volatile profile of hops. XXIV Encontro Luso-Galego de Química
Sociedade Portuguesa de Química (Porto, Portugal)

Supervision

Thesis Title
Role
Degree Subject (Type)
Institution / Organization
2023/08/19 - 2024/12/06 Evaluating the influence of wood ageing variables on beer aroma and sensory attributes: a study under static and dynamic conditions
Supervisor
Controlo da Qualidade (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2008 - 2009 Projeto para implantação de um protocolo de diagnóstico de hemofilia A por biologia molecular no centro de hematologia e hemoterapia do paraná - HEMEPAR
Co-supervisor
Faculty of Pharmacy (Specialization course)
Universidade Federal do Paraná, Brazil

Event organisation

Event name
Type of event (Role)
Institution / Organization
2022/08 - 2024/04 8th International Conference on FOOD DIGESTION (2024/04/09 - 2024/04/11)
Conference (Member of the Organising Committee)
REQUIMTE LAQV Porto, Portugal

Universidade do Porto Faculdade de Farmácia, Portugal
2012 - 2016 Beer excursions around the world (2011 - 2016)
Other (Co-organisor)
Laboratório do Saber, Brazil
2011 - 2014 Beer sommelier courses of Instituto da Cerveja Brasil, in Santa Catarina (2011 - 2014)
Workshop (Co-organisor)
Laboratório do Saber, Brazil

Committee member

Activity description
Role
Institution / Organization
2022/05/27 - Current Member of the EBC Analysis Group, as an expert in the Sensory Sub-Committee. Helping in the development of reference analytical methods for breweries.
Member
The Brewers of Europe, Belgium

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2019/02/23 - Current Workshop of Craft Beer Production Workshop de Produção Artesanal de Cervejas (Outros) Universidade do Porto Faculdade de Farmácia, Portugal
2016 - Current Lectures on chemical and technologic process of hops and beer Master’s degree in Pharmaceutical Sciences (Mestrado integrado) Universidade do Porto Faculdade de Farmácia, Portugal
2023/10/21 - 2023/10/21 Curso básico de controlo de qualidade de lúpulos e cervejas. O curso visa capacitar o participante a executar técnicas laboratoriais fundamentais para a avaliação e garantia de qualidade de lúpulos e cervejas. Curso básico de controlo de qualidade de lúpulos e cervejas (Outros) Universidade do Porto Faculdade de Farmácia, Portugal
2015 - 2017 Workshops of beer tasting Sovina Brewery, Portugal
2016 - 2016 Lecture on sensory analyses of beer Master’s degree in Quality Control (Outros) Universidade do Porto Faculdade de Farmácia, Portugal
2011 - 2014 Workshops of beer tasting and craft beer production Workshops on beer tasting and craft beer production (Outros) Universidade do Vale do Itajaí, Brazil

Other jury / evaluation

Activity description Institution / Organization
2024/11/12 - 2024/11/13 Beer Judge in BBA - Brazilian International Beer Awards