Identification
Personal identification
- Full name
- TIAGO LOPES GOMES
Citation names
- GOMES, TIAGO
Author identifiers
- Ciência ID
- EE1F-A8E4-206F
- ORCID iD
- 0000-0002-3238-290X
Email addresses
- tiagogomes89@gmail.com (Professional)
Addresses
- ITQB NOVA Av. da República , 2780-157, Oeiras, Oeiras, Portugal (Professional)
Knowledge fields
- Natural sciences - Biological Sciences - Biophysics
- Natural sciences - Biological Sciences - Biochemistry
- Natural sciences - Other Natural Sciences
Languages
Language | Speaking | Reading | Writing | Listening | Peer-review |
---|---|---|---|---|---|
Portuguese (Mother tongue) | |||||
English | Advanced (C1) | Advanced (C1) | Advanced (C1) | Advanced (C1) | Advanced (C1) |
Spanish; Castilian | Advanced (C1) | Advanced (C1) | Upper intermediate (B2) | Advanced (C1) | Upper intermediate (B2) |
Catalan | Upper intermediate (B2) | Advanced (C1) | Intermediate (B1) | Advanced (C1) | Upper intermediate (B2) |
Education
Degree | Classification | |
---|---|---|
2013/01/01 - 2019/11/05
Concluded
|
Biomedicina (Doctorat)
Universitat de Barcelona Facultat de Farmacia, Spain
Institut de Recerca Biomèdica, Spain "Into the full-length structure of human Smad proteins and the impact of cancer mutations" (THESIS/DISSERTATION)
|
Excellent cum laude |
2011/01/21
Concluded
|
Química (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
Institut de Recerca Biomèdica, Spain |
|
2010/07/07
Concluded
|
Química (Licenciatura)
Universidade de Lisboa Instituto Superior Técnico, Portugal
|
Affiliation
Science
Category Host institution |
Employer | |
---|---|---|
2022/02/01 - Current | Postdoc (Research) | Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal |
2019/11/05 - 2021/02/28 | Postdoc (Research) | Institut de Recerca Biomèdica, Spain |
2011/06 - 2012/12 | Researcher (Research) | Institut de Recerca Biomèdica, Spain |
Projects
Grant
Designation | Funders | |
---|---|---|
2022/02/01 - Current | HUBs: The architecture of a pathogen-driven signaling hub
PTDC/BIA-BFS/0391/2021
Post-doc
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
|
Fundação para a Ciência e a Tecnologia
Ongoing
|
2014 - 2018 | Stability and DNA binding analysis of tumor mutations present in Smad proteins. Funding awarded of 10000 euros per year between
2014 and 2018. Responsible for program overseeing and experimental execution and co-supervision of master student Angel Vea.
N/A
Researcher
Institut de Recerca Biomèdica, Spain
|
Fundación BBVA
Concluded
|
2013/01/01 - 2016/12/31 | Into the structure of human full-length Smad proteins and the impact of cancer mutations
PhD Student Fellow
Institut de Recerca Biomèdica, Spain
|
Gobierno de España Ministerio de Economía y Empresa
Concluded
|
Contract
Designation | Funders | |
---|---|---|
2019/11/05 - 2020/04/30 | Identificación de los sitios de interacción de proteínas Smad con cofactores mediante el uso de biología estructural de alta
resolución
BFU2017-82675-P (MINECO/FEDER, UE).
Post-doc Fellow
Institut de Recerca Biomèdica, Spain
|
Gobierno de España Ministerio de Economía y Empresa
Concluded
|
Other
Designation | Funders | |
---|---|---|
2020/04 - 2020/12 | Identify inhibitors of the SMAD3 and FOXH1 protein-protein interaction
A19-307
Post-doc
Institut de Recerca Biomèdica, Spain
Atomwise Inc, United States |
Concluded
|
2014 - 2017 | COMUNICACION CELULAR VIA TGFB-SMADS Y DIFERENCIACION DE CELULAS MADRE:ESTRUCTURAS DE SMAD2/FOXH1 UNIDOS AL PROMOTOR GSC. ANALISIS
DE POLIMORFISMOS Y MUTACIONES TUMORALES
BFU2014-53787-P
Researcher
Institut de Recerca Biomèdica, Spain
|
Concluded
|
Outputs
Publications
Conference poster |
|
Journal article |
|
Thesis / Dissertation |
|
Activities
Oral presentation
Presentation title | Event name Host (Event location) |
|
---|---|---|
2023/05/17 | Integrative structural biology of full-length, flexible and oligomeric multidomain proteins involved in pathogenicity. | SCAN seminars (presentation open to the general public, that will be given at the my host institution, regarding past and
future research work)
ITQB-NOVA
|
2023/05/12 | Integrative structural biology of full-length, flexible and oligomeric multidomain proteins involved in pathogenicity (Selected talk). | PostDocs Seminar Exchange Program
NOVA medical school (Lisbon, Portugal)
|
2022/04/21 | Integrative structural biology of full-length Smad transcription factors - key drivers of TGFß signaling. | Postdoc Exchange Seminar Series
Champalimaud Foundation (Lisbon, Portugal)
|
2021/02/12 | First insights into the structures of Smad full-length proteins | INEXT-DISCOVERY 1ST ANNUAL SCIENTIFIC MEETING
CSIC and ITQB-NOVA (Virtual)
|
2020/12/07 | Into the structure of human full-length Smad proteins. | The European Congress on Magnetic Resonance (EUROMAR)
CCbioGUNE (Bilbao, Spain)
|
2019/04 | Into the full-length structure of human Smad proteins | Institute for research in Biomedicine node seminar
Institute for Research in Biomedicine (Barcelona, Spain)
|
2018/05 | Into the structure of human full-length Smad proteins - multi domain proteins driving TGFß signalling. | Institute for research in Biomedicine node seminar
Institute for Research in Biomedicine (Barcelona, Spain)
|
2016/09 | Structural landscape of the human full-length SMAD4 protein – the hub in the TGFß protein family signalling pathway | IRB BioMed conference
Institute for research in biomedicine (Barcelona, Spain)
|
2013/02 | Looking for the one-inch equation in TGF-ß signaling | Institute for research in Biomedicine structural and computational biology program Keynote presentation
Institute for Research in Biomedicine (Barcelona, Spain)
|
2012/04 | Interactions between E3 ubiquitin ligases and Smad proteins - biophysical studies | Institute for research in Biomedicine structural and computational biology program retreat
Institute for Research in Biomedicine (Barcelona, Spain)
|
Supervision
Thesis Title Role |
Degree Subject (Type) Institution / Organization |
|
---|---|---|
2023/09/11 - Current | Enhancing AlphaFold predictions through neighbour-aware structural database sampling
Co-supervisor
|
Biologia Computacional e Bioinformática (Master)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
|
2022/11/01 - 2023/04/30 | Exploring how bacterial effector Tir binds host proteins
Co-supervisor
|
Scientific Research Training C (Iniciação científica) (Scientific initiation)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
|
2022/08/01 - 2022/09/02 | Exploring the role of SARS-CoV-2 nucleocapsid disordered interdomain linker in protein self-assembly.
Supervisor
|
Fellowship of Initiation to Scientific Research (BII) “Verão com Ciência” (Scientific initiation)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
|
2022/02/07 - 2022/06/23 | Role of different SARS-CoV-2 nucleocapsid regions in protein self-assembly and biological function.
Supervisor
|
Biochemistry (Licenciatura/Bacharelato) (Degree)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
|
2016 - 2017 | Stability and DNA binding analysis of tumor mutations present in Smad4
Co-supervisor
|
Master in Genetics and genomics (Master)
Universitat de Barcelona Departament de Biologia Animal, Spain
|
Event participation
Activity description Type of event |
Event name Institution / Organization |
|
---|---|---|
2022/09/30 - Current | Represented my host institution in an outreach activity open to the general public.
Exhibition
|
European Researchers' Night
Fundação para a Ciência e a Tecnologia, Portugal
|
2013/12 - 2013/12 | Workshop in in-cell NMR analysis of biomolecular structure and function
Workshop
|
In-cell NMR analysis of biomolecular structure and function
Università degli Studi di Firenze Centro di Ricerca di Risonanze Magnetiche, Italy
|
2013/01 - 2013/01 | Workshop in advanced methods for the integration of other structural data with NMR data
Workshop
|
Advanced methods for the integration of other structural data with NMR data
Università degli Studi di Firenze Centro di Ricerca di Risonanze Magnetiche, Italy
|
Association member
Society Organization name | Role | |
---|---|---|
2022 - Current | Associação dos Bolseiros de Investigação Científica (ABIC) | Member of this association that represents scholarship holders in issues regarding labour rights. |
Course / Discipline taught
Academic session | Degree Subject (Type) | Institution / Organization | |
---|---|---|---|
2022/03/25 - Current | Integrative Structural Biology of disordered and multidomain proteins (1 day module teaching principles of Integrative structural biology) | Proteins in Disease Mechanisms - MolBioS PhD program (Curso de doutoramento (conclusão de unidades curriculares)) | Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal |
Mentoring / Tutoring
Topic | Student name | |
---|---|---|
2020/03 - 2020/07 | Identification of Smad2 and Smad3 inhibitors. | Míriam Condeminas |
2015/06 - 2015/09 | High-throughput analyses of cancer mutations in Smad4. | Roma Domenech |
Other jury / evaluation
Activity description | Institution / Organization | |
---|---|---|
2022/04/20 - 2022/04/22 | Student poster evaluator for the 12th ITQB NOVA PhD meeting. ITQB NOVA, Oeiras, Portugal. Here I evaluated student posters and wrote a short report evidencing the strengths and weaknesses for each poster. The reports were shared with the students with the indent of improving their scientific presentation skills. | Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal |
Distinctions
Award
2013 | Workshop in in-cell NMR analysis of biomolecular structure and function (travel bursary granted)
Università degli Studi di Firenze Centro di Ricerca di Risonanze Magnetiche, Italy
|
2013 | Workshop in advanced methods for the integration of other structural data with NMR data (travel bursary granted)
Università degli Studi di Firenze Centro di Ricerca di Risonanze Magnetiche, Italy
|
2013 | Severo Ochoa Excellence PhD Programme grant
España Ministerio de Ciencia e Innovación, Spain
|
Title
2019 | PhD defence with cum laude distinction (highest classification possible for the Spanish national education system)
Universitat de Barcelona Facultat de Farmacia, Spain
|
Other distinction
2022 | Post-doctoral grant (BIPD) awarded in an international call associated to a FCT (Fundação para a Ciência e Tecnologia) funded
research project. FCT is the governmental agency that funds national research projects. Grant number: 003/BIPD/2022 (accepted)
Fundação para a Ciência e a Tecnologia, Portugal
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal |
2021 | Margarita Salas grant. Classification of 90/100. Call for a post-doc scholarship given by the Spanish state and the University
of Barcelona (declined)..
University of Barcelona, Spain
|