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Bioactive Lipids; Functional Foods; Probiotics; Genetic Engineering; Molecular Biology; Microbiology; Obesity; Neuroinflammation;
Identification

Personal identification

Full name
Ana Sofia Nobre Salsinha

Citation names

  • Salsinha, Ana Sofia

Author identifiers

Ciência ID
5017-101D-13B0
ORCID iD
0000-0003-1679-299X

Email addresses

  • asalsinha@ucp.pt (Professional)

Addresses

  • CBQF, Escola Superior de Biotecnologia, Universidade Católica do Porto. Rua Arquiteto Lobão Vital, 172, 4200-374, Porto, Porto, Portugal (Professional)

Knowledge fields

  • Natural sciences - Biological Sciences - Virology
  • Agrarian Sciences - Agrarian and Food Biotechnology
  • Medical and Health Sciences - Health Sciences - Nutrition, Dietetics
  • Medical and Health Sciences - Basic Medicine - Neurosciences
  • Natural sciences - Biological Sciences - Microbiology

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Spanish; Castilian Beginner (A1) Intermediate (B1) Beginner (A1) Beginner (A1)
Education
Degree Classification
2019/01/01 - 2024/04/01
Ongoing
 Food Science and Technology and Nutrition (Doutoramento)
Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal

Universidade do Minho, Portugal

Universidade de Aveiro, Portugal
"Utilization of omega 3 and conjugated fatty acids to develop new antiobesity strategies" (THESIS/DISSERTATION)
2016
Concluded
 MSc in Biotechnology (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
"Construction of Virus-like Particles (VLPs) for the Development of Alternative Vaccines agains Maedi-Visna Virus (MVV) and Caprine Arthritis-Encephalitis Virus (CAEV)" (THESIS/DISSERTATION)
 17
2016
Concluded
 Biotecnologia (Mestrado)
Major in Sem especialização
Universidade de Lisboa Instituto Superior Técnico, Portugal
"Construction of Virus-like Particles (VLPs) for the Development of Alternative Vaccines against Maedi-Visna Virus (MVV) and Caprine Arthritis-Encephalitis Virus (CAEV)" (THESIS/DISSERTATION)
2011 - 2014
Concluded
 BSc in Cellular and Molecular Biology (Licenciatura)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
 15
Affiliation

Science

Category
Host institution 		Employer
2023/05/15 - 2025/12/31 Research Assistant (Research) Portuguesa Centro de Biotecnologia e Química Fina, Portugal
Portuguesa Centro de Biotecnologia e Química Fina, Portugal
2014/02/01 - 2014/08/01 Research Trainee (Research) Instituto Nacional de Investigação Agrária e Veterinária, Portugal

Others

Category
Host institution 		Employer
2019/01/01 - 2023/03/01 PhD student Portuguesa Centro de Biotecnologia e Química Fina, Portugal
2017/07/01 - 2018/12/31 Research Fellow Portuguesa Centro de Biotecnologia e Química Fina, Portugal
Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal
2015/09/01 - 2016/11/01 Msc Student Instituto Nacional de Investigação Agrária e Veterinária, Portugal
Projects

Grant

Designation Funders
2019/01 - 2023/03 Utilization of omega 3 and conjugated fatty acids to develop new antiobesity strategies
SFRH/BD/136857/2018
 Fundação para a Ciência e a Tecnologia
2017/02 - 2020/01 Produção Microbiológica de Isómeros Bioactivos de Ácido Linolénico Conjugado para Obtenção de Alimentos e Ingredientes Funcionais
PTDC/AGR-TEC/2125/2014
 Fundação para a Ciência e a Tecnologia

Contract

Designation Funders
2023/05/15 - 2025/12/31 Diet65+ - High nutritional and functional value food products integrated with tradition and sustainability adapted to elderly +65 consumer
C644929456-00000040
Technical development
Portuguesa Centro de Biotecnologia e Química Fina, Portugal
 European Union

Governo da República Portuguesa
Ongoing
2019/01/01 - 2019/12/31 Centro de Biotecnologia e Química Fina
UID/Multi/50016/2019
Universidade Católica Portuguesa, Portugal

Universidade Católica Portuguesa Portuguesa Centro de Biotecnologia e Química Fina, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Book chapter
  1. Ana Sofia Salsinha; Pintado, M.. "Impact of bioactive lipids on gut microbiota". edited by Manuela Pintado; Manuela Machado; Gomes, {Ana Maria, 191-207. Academic Press, 2023.
    10.1016/B978-0-12-824043-4.00008-7
  2. Ana Sofia Salsinha; Renato Socodato; João B. Relvas; Pintado, M.. "The pro- and anti-inflammatory activity of fatty acids". edited by Manuela Pintado; Manuela Machado; Gomes, {Ana Maria, 51-75. Academic Press, 2023.
    10.1016/B978-0-12-824043-4.00002-6
  3. Ana Sofia Salsinha; Rodriguez-Alcalá, L.M.; Lígia Pimentel; Pintado, M.. "Role of bioactive lipids in obesity". edited by Manuela Pintado; Manuela Machado; Gomes, {Ana Maria, 133-167. Academic Press, 2023.
    10.1016/B978-0-12-824043-4.00012-9
  4. Salsinha, Ana Sofia; Machado, Manuela; Rodríguez-Alcalá, Luís Miguel; Gomes, Ana Maria; Pintado, Manuela. "Bioactive lipids: chemistry, biochemistry, and biological properties". Academic Press, 2023.
    10.1016/B978-0-12-824043-4.00014-2
  5. Faustino, Margarida; Salsinha, Ana Sofia; Pimentel, Lígia; Alcalá, Luis; Freitas, Ana Cristina; Gomes, Ana Maria; Pereira, Carlos Dias; Pintado, Manuela. "Characterization of concentrated second cheese whey". 2018.
  6. Pimentel, Lígia Leão; Fontes, Ana Luiza; Salsinha, Ana Sofia; Cardoso, Beatriz Batista; Gomes, Ana Maria; Rodríguez-Alcalá, Luís Miguel. "Microbiological in vivo production of CLNA as a tool in the regulation of host microbiota in obesity control". In Studies in Natural Products Chemistry, 369-394. Elsevier, 2018.
    10.1016/B978-0-444-64183-0.00010-5
Conference abstract
  1. Ana Sofia Salsinha; Renato Socodato; Artur Rodrigues; Rodriguez-Alcalá, L.M.; João B. Relvas; Pintado, M.. "CLA and CLNA ameliorate neuroinflammation and cellular oxidation related with western diets". 2021.
  2. Ana L. Fontes; Lígia Pimentel; Ana Sofia Salsinha; Juan Miguel Rodríguez; M. R. Domingues; Rodriguez-Alcalá, L.M.; Ana Maria Gomes. "Influence of shaking and viable cell numbers on microbial conjugated linoleic acid (CLA) production". 2019.
Conference paper
  1. Fontes, Ana Luiza; Pimentel, Lígia; Calzada, Javier; Salsinha, Ana Sofia; Rodríguez, Juan Miguel; Arqués, Juan; Domingues, Maria do Rosário; et al. "Perspectives on the development of CLA/CLNA-enriched milk through in situ microbial production". 2021.
  2. Fontes, Ana Luiza; Pimentel, Lígia; Salsinha, Ana Sofia; Rodriguez, Juan Miguel; Domingues, MR; Rodríguez-Alcalá, Luís M.; Gomes, Ana Maria. "Influence of shaking and viable cell numbers on microbial conjugated linoleic acid (CLA) production". 2019.
  3. Margarida Faustino; Ana Sofia Salsinha; Lígia Pimentel; Rodriguez-Alcalá, L.M.; A C Freitas; Ana Maria Gomes; Carlos Dias Pereira; Pintado, M.. "Characterization of a concentrated second cheese whey". 2018.
  4. Faustino, Margarida; Salsinha, Ana Sofia; Pimentel, Lígia; Alcalá, Luis; Freitas, Ana Cristina; Gomes, Ana Maria; Pereira, Carlos Dias; Pintado, Manuela. "Characterization of a concentrated second cheese whey". 2018.
  5. Calzada, Javier; Salsinha, Sofia; Pimentel, Lígia; Fontes, Ana Luiza; Gomes, Ana; Arqués, Juan; Rodríguez-Alcalá, Luis Miguel. "Does the presence of linoleate isomerase gene implies conjugated linoleic acid production?". 2017.
  6. Fontes, Ana Luiza; Pimentel, Lígia; Salsinha, Ana Sofia; Cardoso, Beatriz; Andrade, José Carlos; Rodriguéz-Alcalá, Luís Miguel; Gomes, Ana Maria. "Characterization of potential CLA-producing strains according to LA tolerance". 2017.
Conference poster
  1. Ana Sofia Salsinha; A. Rodrigues; R. Socodato; J. B. Relvas; Rodriguez-Alcalá, L.M.; Pintado, M.. "The role of saturated and polyunsaturated fatty acids in microglia modulation". 2021.
  2. Ana Sofia Salsinha; Artur Rodrigues; Renato Socodato; João B. Relvas; Rodriguez-Alcalá, L.M.; Pintado, M.. "Study of inflammation mediated by fatty acids in a microglia cell model - the obesity perspective". 2020.
  3. Ana L. Fontes; Lígia Pimentel; Ana Sofia Salsinha; Juan Miguel Rodríguez; M. Rosário M. Domingues; Rodriguez-Alcalá, L.M.; Ana Maria Gomes. "Influence of shaking and viable cell numbers on microbial conjugated linoleic acid (CLA) production". 2019.
  4. Joana Rocha; João Francisco Botelho; Magdalena Ksiezarek; Teresa Ribeiro; Miguel Machado; João Carriço; Lígia Pimentel; et al. "Lactobacillus femina sp. nov., a new species of Lactobacillus delbrueckii group". 2019.
  5. Ana Sofia Salsinha; A. Rodrigues; R. Socodato; J. B. Relvas; Rodriguez-Alcalá, L.M.; Pintado, M.; Salsinha, Ana Sofia; et al. "Study of inflammation mediated by lipids in a Microglia Cell Model to deepen into brain dysregulation by obesity". Paper presented in 17th Euro Fed Lipid Congress and Expo, 2019.
  6. Ana L. Fontes; Lígia Pimentel; Ana Sofia Salsinha; B. Cardoso; J. C. Andrade; Ana Maria Gomes; Rodriguez-Alcalá, L.M.; et al. "Optimization of linoleic acid emulsion preparation to reduce substrate losses after filter-sterilization". 2017.
  7. Ana L. Fontes; Lígia Pimentel; Ana Sofia Salsinha; Beatriz Batista Cardoso; José Carlos Márcia Andrade; Rodriguez-Alcalá, L.M.; Ana Maria Gomes. "Characterization of potential CLA-producing strains according to LA tolerance". 2017.
  8. Javier Calzada; Ana Sofia Salsinha; Lígia Pimentel; Ana L. Fontes; Ana Maria Gomes; Juan Arqués; Rodriguez-Alcalá, L.M.. "Does the presence of linoleate isomerase gene implies conjugated linoleic acid production?". 2017.
Edited book
  1. Pintado, M.; Manuela Machado; Ana Maria Gomes; Ana Sofia Salsinha; Rodriguez-Alcalá, L.M.. Bioactive lipids. Academic Press. 2023.
    10.1016/C2020-0-01077-7
Journal article
  1. Ana L. Fontes; Lígia Pimentel; Javier Calzada; Ana Sofia Salsinha; Juan Miguel Rodríguez; Ana Maria Gomes; Juan L. Arqués; Rodriguez-Alcalá, L.M.. "Study of the association between genotypic potential and linoleic acid tolerance with microbial production of conjugated linoleic acid". ACS Food Science and Technology 3 12 (2023): 2199-2207. https://ciencia.ucp.pt/en/publications/3e1f80b8-bd67-497b-9e4e-e526ca4de07b.
    10.1021/acsfoodscitech.3c00399
  2. Ana Sofia Salsinha; R. Socodato; A. Rodrigues; R. Vale-Silva; J. B. Relvas; Pintado, M.; Rodriguez-Alcalá, L.M.. "Potential of omega-3 and conjugated fatty acids to control microglia inflammatory imbalance elicited by obesogenic nutrients". Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids 1868 7 (2023): https://ciencia.ucp.pt/en/publications/dacf3ab9-06f9-40b1-b151-c1412d4795fd.
    10.1016/j.bbalip.2023.159331
  3. Ana Sofia Salsinha; Sara A. Cunha; Manuela Machado; Rodriguez-Alcalá, L.M.; João B. Relvas; Pintado, M.. "Assessment of the bioaccessibility and bioavailability prediction of omega 3 and conjugated fatty acids by in vitro standardized digestion model (INFOGEST) and cell model". Food Bioscience 53 (2023): https://ciencia.ucp.pt/en/publications/15b933ac-b920-40db-b764-1c68285fb1aa.
    10.1016/j.fbio.2023.102635
  4. Salsinha, Ana Sofia; Rodríguez-Alcalá, Luis Miguel; Bettencourt Relvas, João; Manuela Pintado. Corresponding author: Manuela Pintado. "Fatty acids role on obesity induced hypothalamus inflammation: From problem to solution – A review". Trends in Food Science & Technology 112 (2021): 592-607. http://dx.doi.org/10.1016/j.tifs.2021.03.042.
    10.1016/j.tifs.2021.03.042
  5. Joana Rocha; João Botelho; Magdalena Ksiezarek; Svetlana Ugarcina Perovic; Miguel Machado; João André Carriço; Lígia L. Pimentel; et al. "Lactobacillus mulieris sp. nov., a new species of Lactobacillus delbrueckii group". International Journal of Systematic and Evolutionary Microbiology 70 3 (2020): 1522-1527. https://doi.org/10.1099/ijsem.0.003901.
    10.1099/ijsem.0.003901
  6. Salsinha, Ana. "Microbial Production of CLA and CLNA rely on a multienzymatic system". Microbiology and Molecular Biology Reviews (2018):
    DOI: 10.1128/MMBR.00019-18
  7. Salsinha, Ana; Pimentel, Lígia; Fontes, Ana Luiza; Salsinha, Sofia; Machado, Manuela; Correia, Inês; Gomes, Ana Maria; Pintado, Manuela; Rodríguez-Alcalá, Luis Miguel. "Suitable simple and fast methods for selective isolation of phospholipids as a tool for their analysis". Electrophoresis (2018): http://hdl.handle.net/10400.14/25717.
    10.1002/elps.201700425

Other

Other output
  1. In vitro gastrointestinal digestion impact on the antioxidant activity of extracts produced from the microalgae chlorella vulgaris and nannochloropsis oceanica. 2021. Sara A. Cunha; Ana Sofia Salsinha; Joana Laranjeira Silva; Pintado, M.; Paulo Nova; Ana Maria Gomes. https://ciencia.ucp.pt/en/publications/8e9a663a-aadb-41c2-9160-025f267e7c7f.
    10.3390/foods2021-11069