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Pedro Jorge Araújo Alves da Silva. Completed the Doutoramento in Química in 2001 by Universidade do Porto and Licenciatura in Bioquímica in 1996 by Universidade do Porto. Is Associate Professor in Universidade Fernando Pessoa. Published 38 articles in journals. Has 1 book(s). Organized 2 event(s). Supervised 2 MSc dissertation(s). Has received 1 awards and/or honors. Participates and/or participated as Principal investigator in 2 project(s). Works in the area(s) of Natural sciences with emphasis on Biological Sciences and Exact Sciences with emphasis on Chemical Sciences with emphasis on Physical Chemistry. In their professional activities interacted with 51 collaborator(s) co-authorship of scientific papers. In his curriculum Ciência Vitae the most frequent terms in the context of scientific, technological and artistic-cultural output are: photochemistry; pontes dissulfureto; enzimologia; TDDFT; ressonância; efeito indutivo; quantum tunneling; reaction mechanism; acoplagem molecular; dinâmica molecular; reverse screening; .
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Identification

Personal identification

Full name
Pedro Jorge Araújo Alves da Silva

Citation names

  • Silva, Pedro J.

Author identifiers

Ciência ID
3417-E1EE-66A5
ORCID iD
0000-0001-9316-9275

Websites

Knowledge fields

  • Natural sciences - Biological Sciences
  • Exact Sciences - Chemical Sciences - Physical Chemistry

Languages

Language Speaking Reading Writing Listening Peer-review
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
French Beginner (A1) Advanced (C1) Beginner (A1) Intermediate (B1)
Dutch Intermediate (B1) Intermediate (B1) Beginner (A1) Intermediate (B1)
Education
Degree Classification
1997 - 2001
Concluded
 Química (Doutoramento)
Universidade do Porto, Portugal
"Isolation and characterization of enzymes involved in the hydrogen metabolsim from Pyrococcus furiosus" (THESIS/DISSERTATION)
 Aprovado por unanimidade
1992 - 1996
Concluded
 Bioquímica (Licenciatura)
Universidade do Porto, Portugal
 16
Affiliation

Teaching in Higher Education

Category
Host institution 		Employer
2010/10 - 2023/08/31 Associate Professor (University Teacher) Universidade Fernando Pessoa, Portugal
2001/04 - 2010/09 Assistant Professor (University Teacher) Universidade Fernando Pessoa, Portugal
Projects

Contract

Designation Funders
2022/01/04 - Current Identification of the cellular targets of novel antibiotics
ACX regrant
Principal investigator
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
 Centre for Effective Altruism
Ongoing

Other

Designation Funders
2011/01 - 2014/08 Estudos computationais de reações orgânicas catalizadas por metais de transição
PTDC/QUI-QUI/111288/2009
Principal investigator
Universidade Fernando Pessoa, Portugal
Concluded
Outputs

Publications

Book
  1. Silva, Pedro J.; Carla Sousa e Silva; Catarina Lemos; Fernanda Leal; Inês Lopes Cardoso; Marta Oliveira; Carla Moutinho. Trabalhos Laboratoriais de Bioquímica. ISBN: 978-989-643-077-1. Porto: .. Porto: Edições UFP. 2011.
    Published
Conference abstract
  1. Silva, Pedro J.; Ramos, Maria João. "The reaction mechanism of the light-dependent step in the protochlorphyllide oxidoreductase reaction mechanism". Paper presented in 13th International Conference on Qunatum Chemistry, Helsínquia, 2009.
    Published
  2. Silva, Pedro Jorge Araújo Alves da; Ramos, Maria João. "On the role of arginine residues as general acids in two steps of the reaction mechanism of uroporphyrinogen decarboxylase". Paper presented in 8th European Conference on Bioinorganic Chemistry, Aveiro, 2006.
    Published
  3. Silva, Pedro Jorge Araújo Alves da; Ramos, Maria João. "A computational study of the reaction mechanism of coproporphyrinogen oxidase". Paper presented in Trends in Enzymology, Como, Itália, 2006.
    Published
  4. Silva, Pedro Jorge Araújo Alves da; Ramos, Maria João. "A QM/MM study of the reaction mechanism of uroporphyrinogen decarboxylase". Paper presented in Quantum Chemistry Applied: From H3 to biocatalysis, Estocolmo, 2005.
    Published
  5. Silva, Pedro Jorge Araújo Alves da; Ramos, Maria João. "Evaluation of mechanisms for the cofactor-free decarboxylation performed by uroporphyrinogen III decarboxylase". Paper presented in 7º Encontro Nacional de Química Física, Porto, 2005.
    Published
  6. Silva, Pedro Jorge Araújo Alves da; Ramos, Maria João. "Detecting structural homologs through hydrophobic cluster analysis". Paper presented in 3º Congresso Luso-Espanhol de Biofísica, Lisboa, 2004.
    Published
  7. Silva, Pedro Jorge Araújo Alves da; Ramos, Maria João. "Pyrrole protonation and decarboxylation by uroporphyrinogen III decarboxylase". Paper presented in 30º Congresso de Químicos Teóricos de Expressão Latina, Porto, 2004.
    Published
  8. Silva, Pedro Jorge Araújo Alves da; Ramos, Maria João; Fernandes, Pedro A.. "A density functional study of arachidonic acid cyclooxygenation by prostaglandin H synthase". Paper presented in “Modelling Chemical Reactivity : From Gas - Phase to solution and enzymes”, Nancy, 2003.
    Published
  9. Silva, Pedro Jorge Araújo Alves da; Wilfred R. Hagen. "The membrane-bound hydrogenase from Pyrococcus furiosus: isolation, kinetic characterization and redox properties". Paper presented in 6th International Conference on the Molecular Biology of Hydrogenases, Potsdam, 2000.
    Published
  10. Silva, Pedro Jorge Araújo Alves da; Maria João Amorim; Peter-Leon Hagedoorn; Hans Wassink; Huub Haaker; Wilfred R. Hagen. "Effects of temperature on the electron transfer between Pyrococcus furiosus hydrogenase and its redox partners.". Paper presented in 9th International Conference on Biological Inorganic Chemistry, Minneapolis, 1999.
    Published
  11. Silva, Pedro Jorge Araújo Alves da; Maria João Amorim; Peter-Leon Hagedoorn; Hans Wassink; Huub Haaker; Wilfred R. Hagen. "On the prosthetic groups of the NiFe sulfhydrogenase from Pyrococcus furiosus and its putative redox partners: topology, structure, and temperature-dependent redox chemistry.". Paper presented in COST ACTION 818 Workshop on Bacterial Hydrogenases: Structures and Mechanisms, Sintra, 1998.
    Published
  12. Silva, Pedro Jorge Araújo Alves da; Wilfred R. Hagen. "Multiple forms of EPR-detectable nickel in Pyrococcus furiosus sulfhydrogenase generated by temperature-change induced auto-redox cycling". Paper presented in 4th European Conference on Bioinorganic Chemistry, Sevilha, 1998.
    Published
Journal article
  1. Pedro J. Silva. "Computational insights into the spontaneity of epoxide formation from halohydrins and other mechanistic details of Williamson’s ether synthesis". Chemistry Journal of Moldova (2023): https://doi.org/10.19261/cjm.2023.1083.
    10.19261/cjm.2023.1083
  2. Tomasz M. Karpinski; Marcin Ozarowski; Pedro J. Silva; Mark Stasiewicz; Rahat Alam; Abdus Samad. "Discovery of Terpenes as Novel HCV NS5B Polymerase Inhibitors via Molecular Docking". Pathogens (2023): https://doi.org/10.3390/pathogens12060842.
    10.3390/pathogens12060842
  3. Pedro J. Silva. "The Reaction Mechanism of the Cu(I) Catalyzed Alkylation of Heterosubstituted Alkynes". Catalysts (2022): https://doi.org/10.3390/catal13010017.
    10.3390/catal13010017
  4. Pedro J. Silva; Maria Osswald-Claro; Rosário Castro Mendonça. "How to tune the absorption spectrum of chlorophylls to enable better use of the available solar spectrum". PeerJ Physical Chemistry 4 (2022): e26-e26. http://dx.doi.org/10.7717/peerj-pchem.26.
    10.7717/peerj-pchem.26
  5. Pedro J. Silva. "Computational Development of Inhibitors of Plasmid-Borne Bacterial Dihydrofolate Reductase". Antibiotics 11 6 (2022): 779-779. http://dx.doi.org/10.3390/antibiotics11060779.
    10.3390/antibiotics11060779
  6. Silva, Pedro J.; Cheng, Qi. "An Alternative Proposal for the Reaction Mechanism of Light-Dependent Protochlorophyllide Oxidoreductase". ACS Catalysis 12 4 (2022): 2589-2605. http://dx.doi.org/10.1021/acscatal.1c05351.
    Published • 10.1021/acscatal.1c05351
  7. Pedro J. Silva; Carlos E. P. Bernardo. "Unveiling the Reaction Mechanism of the Das/Chechik/Marek Synthesis of Stereodefined Quaternary Carbon Centers". Applied Sciences 11 11 (2021): 5002-5002. https://doi.org/10.3390/app11115002.
    10.3390/app11115002
  8. Silva, Pedro J.. "Response to "Molecular-level understanding of biological energy coupling and transduction"". Biophysical Chemistry (2021):
    10.1016/j.bpc.2020.106512
  9. Pedro J. Silva. "New insights into the mechanism of Schiff base synthesis from aromatic amines in the absence of acid catalyst or polar solvents". PeerJ Organic Chemistry (2020): https://doi.org/10.7717/peerj-ochem.4.
    10.7717/peerj-ochem.4
  10. Silva, Pedro J.. "Chemiosmotic misunderstandings". Biophysical Chemistry (2020): http://dx.doi.org/10.1016/j.bpc.2020.106424.
    10.1016/j.bpc.2020.106424
  11. Sandra V. R. L. Silva; Pedro J. Silva. "Computational improvement of small-molecule inhibitors of Bacillus anthracis protective antigen activation through isostere-based substitutions". Journal of Biomolecular Structure and Dynamics (2020): https://doi.org/10.1080/07391102.2020.1792987.
    10.1080/07391102.2020.1792987
  12. Silva, Pedro J.; Bernardo, Carlos E. P.. "Influence of Alkyne and Azide Substituents on the Choice of the Reaction Mechanism of the Cu+-Catalyzed Addition of Azides to Iodoalkynes". The Journal of Physical Chemistry A 122 37 (2018): 7497-7507. http://dx.doi.org/10.1021/acs.jpca.8b06894.
    Published • 10.1021/acs.jpca.8b06894
  13. Bernardo, Carlos E. P.; Silva, Pedro J.. "Computational exploration of the reaction mechanism of the Cu+-catalysed synthesis of indoles from N-aryl enaminones". Royal Society Open Science 2 3 (2016): 150582-150582.
    Open access • Published • 10.1098/rsos.150582
  14. Silva, Pedro J.. "Will 1,2-dihydro-1,2-azaborine-based drugs resist metabolism by cytochrome P450 compound I?". PeerJ 4 (2016): e2299-e2299.
    Open access • Published • 10.7717/peerj.2299
  15. Silva, Pedro J.. "Refining the reaction mechanism of O2 towards its co-substrate in cofactor-free dioxygenases.". PeerJ 4 (2016): e2805-e2805.
    Open access • Published • 10.7717/peerj.2805
  16. Silva, Pedro J.; Rodrigues, Viviana. "Mechanistic pathways of mercury removal from the organomercurial lyase active site". PeerJ 3 (2015): e1127-e1127.
    Open access • Published • 10.7717/peerj.1127
  17. Bernardo, Carlos E.P.; Silva, Pedro J.. "Computational development of rubromycin-based lead compounds for HIV-1 reverse transcriptase inhibition". PeerJ 2 2 (2014): e470-e470.
    Open access • Published • 10.7717/peerj.470
  18. Silva, Pedro J.. "With or without light: comparing the reaction mechanism of dark-operative protochlorophyllide oxidoreductase with the energetic requirements of the light-dependent protochlorophyllide oxidoreductase". PeerJ 2 2 (2014): e551-e551.
    Open access • Published • 10.7717/peerj.551
  19. Sousa, Carla; Silva, Pedro J.. "BBr3-Assisted Cleavage of Most Ethers Does Not Follow the Commonly Assumed Mechanism". European Journal of Organic Chemistry 2013 23 (2013): 5195-5199.
    Published • 10.1002/ejoc.201300337
  20. Bernardo, Carlos E. P.; Bauman, Nicholas P.; Piecuch, Piotr; Silva, Pedro J.. "Evaluation of density functional methods on the geometric and energetic descriptions of species involved in Cu+-promoted catalysis". Journal of Molecular Modeling 19 (2013): 5457-5467.
    Published • 10.1007/s00894-013-2045-z
  21. Silva, P.J.; Perez, M.A.S.; Brás, N.F.; Fernandes, P.A.; Ramos, M.J.. "Erratum to: Improving the study of proton transfers between amino acid side chains in solution: Choosing appropriate DFT functionals and avoiding hidden pitfalls (Theor Chem Acc, (2012) 131, 117, 10.1007/s00214-012-1179-x)". Theoretical Chemistry Accounts 132 2 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84875366125&partnerID=MN8TOARS.
    10.1007/s00214-012-1307-7
  22. Sousa, C.; Silva, P.J.. "Erratum: BBr3-Assisted Cleavage of Most Ethers Does Not Follow the Commonly Assumed Mechanism(European Journal of Organic Chemistry (2013) (8048-8049))". European Journal of Organic Chemistry 35 (2013): 8048-8049. http://www.scopus.com/inward/record.url?eid=2-s2.0-84889089698&partnerID=MN8TOARS.
    10.1002/ejoc.201301647
  23. Silva, Pedro J.; Perez, Marta A. S.; Brás, Natércia F.; Fernandes, Pedro A.; Ramos, M. J.. "Improving the study of proton transfers between amino acid side chains in solution: choosing appropriate DFT functionals and avoiding hidden pitfalls". Theoretical Chemistry Accounts 131 3 (2012): 1179-1185.
    Published • 10.1007/s00214-012-1179-x
  24. Silva, Pedro Jorge. "Unravelling the reaction mechanism of the reductive ring contraction of 1,2-pyridazines.". Journal of Organic Chemistry 77 (2012): 4653-4659.
    Published • 10.1021/jo300448d
  25. Silva, Pedro J.; Ramos, Maria João. "Computational Characterization of the Substrate-Binding Mode in Coproporphyrinogen III Oxidase". Journal of Physical Chemistry B 115 8 (2011): 1903-1910.
    Published • 10.1021/jp110289d
  26. Silva, Pedro J.; Ramos, Maria João. "Successes and failures of DFT functionals in acid/base and redox reactions of organic and biochemical interest". Computational and Theoretical Chemistry 966 1-3 (2011): 120-126.
    Published • 10.1016/j.comptc.2011.02.022
  27. Brás, Natércia F.; Perez, Marta A. S.; Fernandes, Pedro A.; Silva, Pedro J.; Ramos, Maria J.. "Accuracy of Density Functionals in the Prediction of Electronic Proton Affinities of Amino Acid Side Chains". Journal of Chemical Theory and Computation 7 (2011): 3898-3908.
    Published • 10.1021/ct200309v
  28. Silva, Pedro J.; Ramos, Maria João. "Computational insights into the photochemical step of the reaction catalyzed by protochlorophylide oxidoreductase.". International JOurnal of Quantum Chemistry 111 (2010): 1472-1479. http://dx.doi.org/10.1002/qua.22671.
    Published • 10.1002/qua.22671
  29. Silva, Pedro J.; Schulz, Claudia; Jahn, Dieter; Jahn, Martina; Ramos, Maria Joa~o. "A Tale of Two Acids: When Arginine Is a More Appropriate Acid than H 3 O +". Journal of Physical Chemistry B 114 27 (2010): 8994-9001.
    Published • 10.1021/jp100961s
  30. Silva, Pedro Jorge Araújo Alves da. "Inductive and Resonance Effects on the Acidities of Phenol, Enols, and Carbonyl a-Hydrogens.". Journal of Organic Chemistry 74 (2009): 914-916. http://pubs.acs.org/doi/pdf/10.1021/jo8018736.
    Published • 10.1021/jo8018736
  31. Silva, Pedro J.; Ramos, Maria João. "Computational studies on the reactivity of substituted 1,2-dihydro-1,2-azaborines". Journal of Organic Chemistry 74 (2009): 6120-6129. http://dx.doi.org/10.1021/jo900980d.
    Published • 10.1021/jo900980d
  32. Silva, Pedro Jorge Araújo Alves da. "Assessing the reliability of sequence similarities detected through hydrophobic sequence analysis". Proteins-Structure Function and Bioinformatics 70 (2008): 1588-1594. http://dx.doi.org/10.1002/prot.21803.
    Published • 10.1002/prot.21803
  33. van Haaster, DJ; Silva, Pedro Jorge Araújo Alves da; Peter-Leon Hagedoorn; Jongejaan, Jaap; Wilfred R. Hagen. "A re-investigation of the steady-state kinetics and the physiological function of the soluble NiFe-hydrogenase-I of Pyrococcus furiosus.". Journal of Bacteriology 190 (2008): 1584-1587. http://dx.doi.org/10.1128/JB.01562-07.
    Published • 10.1128/JB.01562-07
  34. Silva, Pedro Jorge Araújo Alves da; Ramos, Maria João. "A comparative density-functional study of models for the reaction mechanism of uroporphyrinogen III synthase.". Journal of Physical Chemistry B 112 (2008): 3144-3148. http://dx.doi.org/10.1021/jp076235f.
    Published • 10.1021/jp076235f
  35. Silva, Pedro Jorge Araújo Alves da; Ramos, Maria João. "A comparative density-functional study of the reaction mechanism of the O2-dependent coproporphyrinogen III oxidase.". Bioorganic & Medicinal Chemistry 16 (2008): 2726-2733. http://dx.doi.org/10.1016/j.bmc.2008.01.008.
    Published • 10.1016/j.bmc.2008.01.008
  36. Silva, Pedro Jorge Araújo Alves da; Ramos, Maria João. "Reaction Mechanism of the Vitamin K-Dependent Glutamate Carboxylase: A Computational Study.". Journal of Physical Chemistry B 111 (2007): 12883-12887. http://dx.doi.org/10.1021/jp0738208.
    Published • 10.1021/jp0738208
  37. Pinho, Dora; Silva, Pedro Jorge Araújo Alves da; Besson, Stéphane; Baltazar de Castro; Moura, Isabel. "Isolation and spectroscopic characterization of the membrane-bound nitrate reductase from Pseudomonas chlororaphis DSM 50135". Biochimica et Biophysica Acta-General Subjects 1723 (2005): 151-162. http://dx.doi.org/10.1016/j.bbagen.2005.02.008.
    Published • 10.1016/j.bbagen.2005.02.008
  38. Silva, Pedro Jorge Araújo Alves da; Ramos, Maria João. "A Density-Functional Study of Mechanisms for the Cofactor-Free Decarboxylation Performed by Uroporphyrinogen III Decarboxylase.". Journal of Physical Chemistry B 109 (2005): 18195-18200. http://dx.doi.org/10.1021/jp051792s.
    Published • 10.1021/jp051792s
  39. de Bok, F.; Wilfred R. Hagen; Peter-Leon Hagedoorn; Silva, Pedro Jorge Araújo Alves da; Fritsche, Kathrin; Stams, Alfons; Schiltz, Emile. "Two W-containing formate dehydrogenases (CO2-reductases) involved in syntrophic propionate oxidation by Syntrophobacter fumaroxidans.". European Journal of Biochemistry 270 (2003): 2476-2485. http://dx.doi.org/10.1046/j.1432-1033.2003.03619.x.
    Published • 10.1046/j.1432-1033.2003.03619.x
  40. Silva, Pedro Jorge Araújo Alves da; Fernandes, Pedro A.; Ramos, Maria João. "A theoretical study of radical-only and combined radical/carbocationic mechanisms of arachidonic acid cyclooxygenation by prostaglandin H synthase.". Theoretical Chemistry Accounts 110 (2003): 345-351. http://dx.doi.org/10.1007/s00214-003-0476-9.
    Published • 10.1007/s00214-003-0476-9
  41. Silva, Pedro Jorge Araújo Alves da; Wilfred R. Hagen; Hans Wassink; Huub Haaker; Peter-Leon Hagedoorn; Maria João Amorim; Frank T. Robb; Silva, Pedro J.. "Novel structure and redox chemistry of the prosthetic groups of the iron-sulfur flavoprotein sulfide dehydrogenase from Pyrococcus furiosus; evidence for a [2Fe-2S] cluster with Asp(Cys) 3 ligands.". Journal of Biological Inorganic Chemistry 5 5 (2000): 527-534. http://dx.doi.org/10.1007/s007750050013.
    Published • 10.1007/s007750050013
  42. Silva, Pedro Jorge Araújo Alves da; Baltazar de Castro; Frank T. Robb; Wilfred R. Hagen; Huub Haaker; Hans Wassink; Eyke C. D: van den Baan. "Enzymes of hydrogen metabolism in Pyrococcus furiosus.". European Journal of Biochemistry 267 (2000): 6541-6551. http://dx.doi.org/10.1046/j.1432-1327.2000.01745.x.
    Published • 10.1046/j.1432-1327.2000.01745.x
  43. Silva, Pedro Jorge Araújo Alves da; Wilfred R. Hagen; Baltazar de Castro. "On the prosthetic groups of the NiFe sulfhydrogenase from Pyrococcus furiosus: topology, structure, and temperature-dependent redox chemistry.". Journal of Biological Inorganic Chemistry 4 (1999): 284-191. http://dx.doi.org/10.1007/s007750050314.
    Published • 10.1007/s007750050314
Manual
  1. Silva, Pedro J.; Inês Lopes Cardoso; Catarina Lemos; Fernanda Leal; Carla Moutinho; Carla Sousa e Silva; Marta Oliveira. Trabalhos Laboratoriais de Bioquímica. Portugal. 2011.
  2. Silva, Pedro Jorge Araújo Alves da. Physiological Chemistry. 2006.
  3. Silva, Pedro Jorge Araújo Alves da. Resolução comentada de exercícios de Química Analítica. 2005.
  4. Silva, Pedro Jorge Araújo Alves da. Química Fisiológica. 2005.
  5. Silva, Pedro Jorge Araújo Alves da. Animações sobre temas de bioquímica estrutural e metabólica. 2004.
  6. Silva, Pedro Jorge Araújo Alves da. A general overview of the major metabolic pathways. 2003.
  7. Silva, Pedro Jorge Araújo Alves da. Uma panorâmica geral das vias metabólicas. 2002.
  8. Silva, Pedro Jorge Araújo Alves da. Lições Introdutórias de Química Orgânica. 2001.
Preprint
  1. Silva, Pedro. "Learning from failures: anatomy and post-mortem analysis of an unsuccessful search for inhibitors of SARS-CoV2 papain-like protease". 2025. https://doi.org/10.26434/chemrxiv-2025-6245x.
    10.26434/chemrxiv-2025-6245x
  2. Sun, Xizhe; Ma, Lisong; Zeng, Fanli; Hong, Yiguo; Dixon, Ray; Rao, Zihe; Zhao, Guogang; et al. Corresponding author: Silva, Pedro J.. "Structure-based analysis unveils co-origin of LPOR and nitrogenase-like proteins". 2025. https://doi.org/10.1101/2025.02.17.634645.
    10.1101/2025.02.17.634645
Thesis / Dissertation
  1. "Isolation and characterization of enzymes involved in the hydrogen metabolism from Pyrococcus furiosus". PhD, 2001. https://purl.pt/6339 http://homepage.ufp.pt/pedros/science/phd.pdf.

Other

Other output
  1. HCA Database. Software. 2008. Silva, Pedro Jorge Araújo Alves da. http://homepage.ufp.pt/pedros/HCA_db/index.htm.
  2. HCA_analyze. Software. 2008. Silva, Pedro J.. http://homepage.ufp.pt/pedros/HCA_db/downloads.htm.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2011 With or without light:Biological reduction of protochlorophylide by two unrelated enzymes 5th Symposium on Theoretical Biophysics
(Funchal, Portugal)
2011 Reactivity of cytochrome P450 towards 1,2-dihydro-1,2-azaborine 9th Triennial Conference of the World Association of Theoretical and Computational Chemists
World Association of Theoretical and Computational Chemists (Santiago de Compostela, Spain)
2008 Computational studies of heme biosynthesis Biomolecular Simulation 2008: frontiers of biomolecular simulation
(Bristol, United Kingdom)
2000 One, two, three, many: Enzymes of hydrogen metabolism in Pyrococcus furiosus 6th International Conference on the Molecular Biology of Hydrogenases
(Potsdam, Germany)
2000 Novel Structure and Redox Chemistry of the Prosthetic Groups of the Iron-Sulfur Flavoprotein Sulfide Dehydrogenase from Pyrococcus furiosus Third International Congress on Extremophiles
(Hamburgo, Germany)
1999 Os grupos prostéticos da [NiFe]-sulfhidrogenase do Pyrococcus furiosus: topologia, estrutura e química redox dependente da temperatura 1º Encontro RequiMTe
(Portugal)
1998 Hyperthermophilic redox biochemistry revisited: Em(T) profiles of rubredoxin and ferredoxin from Pyrococcus furiosus. 4th European Conference on Bio-inorganic Chemistry
(Sevilha, Spain)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2015 - 2015 Pesquisa Computacional de Inibidores de Fatores de Virulência de Bacillus anthracis
Supervisor
 Mestrado Integrado em Ciências Farmacêuticas (Master)
Universidade Fernando Pessoa, Portugal
2010 - 2010 Mecanismo de destoxificação do dimetilmercúrio
Supervisor
 Mestrado Integrado em Ciências Farmacêuticas (Master)
Universidade Fernando Pessoa, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2007 - 2007 Jornada sobre a Humanização dos Cuidados de Saúde
Meeting (Co-organisor)
2006 - 2006 Jornada de Bioética
Meeting (Co-organisor)

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2020/12/04 Identification of New Drugs Against Biofilm Formation and Development
(Thesis) Main arguer
 Fábio António Gouveia Ferreira Martins (Master)
Universidade do Porto Faculdade de Ciências, Portugal
2019/03/22 Fatty acid synthase – Catalytic mechanism
(Thesis) Main arguer
 Fabiola Estefany Medina Narvaez (PhD)
Universidade do Porto Faculdade de Ciências, Portugal
2018/09/11 The origin of the catalytic power of enzymes
(Thesis) Main arguer
 Ana Rita de Almeida Calixto (PhD)
Universidade do Porto Faculdade de Desporto, Portugal
2017 Integrating a new scoring function into molecular docking for the design of glucosidase inhibitors Diogo Santos Martins (PhD)
Universidade do Porto, Portugal
2017 New therapeutic strategies to lower blood cholesterol levels through the inhibition of HMG-CoA reductase Diana Sofia Gesto da Silva (PhD)
Universidade do Porto, Portugal
2017 Drug transport across cell membranes João Tiago Soares Coimbra (PhD)
Universidade do Porto, Portugal
2016 Mechanistic diversity of PLP-dependent enzymes Eduardo Filipe Teixeira de Oliveira (PhD)
Universidade do Porto, Portugal
2016 Metals’ data for biomolecular forcefield Rui Pedro Pimenta das Neves (PhD)
Universidade do Porto, Portugal
2015 New computational methods to calculate drug-receptor binding free energie Sílvia Alexandra Pinto Martins (PhD)
Universidade do Porto, Portugal
2014 Theoretical studies on oxidosqualene cyclase: a new target to control cholesterol biosynthesis Óscar Abílio Leal Ferreira Passos (Other)
Universidade do Porto, Portugal
2014 Theoretical studies on oxidosqualene cyclase: a new target to control cholesterol biosynthesis João Tiago Soares Coimbra (Other)
Universidade do Porto, Portugal
2014 Enzymatic studies of oxidosqualene cyclase and glutamine synthetase Cátia Daniela dos Santos Moreira (Other)
Universidade do Porto, Portugal
2013 The Role of Non-coding DNA Structural Information in Phylogeny, Evolution and Disease João Miguel Sotto Maior Faria Carneiro (PhD)
Universidade do Porto, Portugal
2013 Drug Design targeted at HIV-1 Integrase António José Meireles Ribeiro (PhD)
Universidade do Porto, Portugal
2012 Fractalidade em moléculas informacionais Juan António Casas Tamames (PhD)
Universidade do Porto, Portugal
2012 Metabolismo do etanol Joana Margarida Fernandes Vieira (Master)
Universidade Fernando Pessoa, Portugal
2011 Glutathion transferase: Theoretical insights Daniel Fernando Andrade Ribeiro Dourado (PhD)
Universidade do Porto, Portugal
2010 Estudo do Mecanismo da Enzima Ornitina Descarboxilase Eduardo Filipe Teixeira de Oliveira (Master)
Universidade do Porto, Portugal
2010 Estudo Teórico de Pontes Dissulfureto em Proteínas José Rui Ferreira Marques (PhD)
Universidade do Porto, Portugal
2010 Computer simulation studies of the interaction between carbon nanotubes and macromolecules Karol Strutyski (Other)
Universidade do Porto, Portugal
2009 Computational studies on amyloid-beta binding alcohol dehydrogenase and geranylgeranyltransferase type-I enzymes Alexandra Tavares Marques (PhD)
Universidade do Porto, Portugal
2009 Desenvolvimento de Novos Fármacos Anti-Colesterol - o caminho desbravado Ana Rute de Azevedo Pina Neves (Master)
Universidade do Porto, Portugal
2008 Computational and modelling studies on metalloproteins: Cu,Zn superoxide dismutase and engineered cytochrome P450 monooxygenases Ricardo Flores Branco (PhD)
Universidade do Porto, Portugal
2008 Novos agentes para tratamento de infecções por HIV-1 Sílvia Martins (Master)
Universidade do Porto, Portugal

Ad Hoc journal article review

Journal title (ISSN) Publisher
2021/10/01 - Current Journal of Chemical Information and Modeling
2021/04/01 - Current Chemical Papers
2021/02/14 - Current Journal of Photochemistry and Photobiology
2020/12/01 - Current Cell Biochemistry and Biophysics
2020/12/01 - Current Journal of Molecular Graphics and Modeling
2020/12/01 - Current PeerJ Inorganic Chemistry
2020/11/01 - Current Antibiotics MDPI
2020/08/01 - Current Biosystems Elsevier
2020/07/04 - Current Biophysical Chemistry Elesevier
2020/07/01 - Current Catalysts
2020/07/01 - Current Chemistry - A European Journal
2020/06/03 - Current Catalysis Communications
2019/11/01 - Current Applied Sciences MDPI
2019/10 - Current International Journal of Molecular Sciences
2019/07/01 - Current PeerJ Physical Chemistry
2019/06/01 - Current Medicinal Chemistry
2019/02/01 - Current ACS Omega
2018/12/01 - Current Journal of Molecular Modeling
2018/11/01 - Current Oriental Journal of Chemistry
2018/10/01 - Current Marine Drugs
2018/04/08 - Current Biomolecules MDPI
2018/04/01 - Current Theoretical Chemistry Accounts
2018/01/01 - Current ACS Catalysis
2018/01/01 - Current Letters in Drug Design
2017/12/14 - Current PeerJ
2017/12/01 - Current Medicinal Chemistry Research
2017/11/01 - Current Molecules
2017/09/01 - Current Scientific Reports
2017/07/01 - Current Journal of Molecular Liquids
2017/06/01 - Current Inorganic Chemistry
2017/01/01 - Current Biochemistry
2016/05/01 - Current RSC Advances
2016/03/21 - Current Molecular Pharmaceuticals
2016/03/14 - Current Molecular Pharmaceutics
2016/01/14 - Current European Physical Journal D
2016/01/05 - Current PLOS One
2015/09/01 - Current New Journal of Chemistry
2013/08/10 - Current Journal of Physical Chemistry
2013/01/01 - Current BMC Bioinformatics
2012/05/16 - Current Tetrahedron Letters
2009/09/01 - Current Journal of Chemical Theory and Computation
2009/06/01 - Current Journal of Organic Chemistry
2018/08/01 - 2020/12/31 Journal of Biomolecular Structure and Dynamics

Journal scientific committee

Journal title (ISSN) Publisher
2015/09/10 - Current PeerJ
Distinctions

Other distinction

2018 Section Editor (Biochemistry, Biophysics and Molecular Biology)
PeerJ Inc, United States