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Identification

Personal identification

Full name
Tatiana Barros Reis Cereija

Citation names

  • Cereija, T.B.

Author identifiers

Ciência ID
0D1B-2EB5-80B8
ORCID iD
0000-0002-7176-0205

Email addresses

  • tatiana.cereija@i3s.up.pt (Professional)

Addresses

  • i3S, Rua Alfredo Allen, 208, 4200-135, Porto, Porto, Portugal (Professional)
Education
Degree Classification
2018/06/29
Concluded
Biologia Molecular e Celular (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
"Biochemical and structural characterization of novel mycobacterial drug targets " (THESIS/DISSERTATION)
Approved
2010
Concluded
Biologia Molecular e Celular (Mestrado)
Universidade de Aveiro, Portugal
"Characterization of trypsin inhibition by boophilin" (THESIS/DISSERTATION)
16 (out of 20)
Outputs

Publications

Book chapter
  1. Felgueiras, C.; Cereija, T.B.; Machado, A.; Cerca, N.; Rodrigues, L.R.. "Lactobacilli and its Metabolites as Potential Probiotics against Gardnerella vaginalis". In Industrial, medical and environmental applications of microorganisms Current status and trends, 541-545. Wageningen, Netherlands: Wageningen Academic Publishers, 2014.
    Published
Conference poster
  1. Cereija, T.B.; Morais-Cabral, J.H.. "Ligand regulated CPA K+/H+ antiporter". Paper presented in INSTRUCT cryo-EM workshop on sample preparation for Single Particle Analysis (Grenoble, France), 2023.
  2. Cereija, T.B.; Guerra, J.P.L.,; Morais-Cabral, J.H.. "Atypical RCK domain present in a two component K+/H+ antiporter". Paper presented in 63rd Annual Meeting of the Biophysical Society (Baltimore, Maryland, USA), 2019.
  3. Monteiro, R.; Meireles, D.; Cereija, T.B.; Pombinho, A.; Morais-Cabral, J.H.; Sousa, S.; Cabanes, D.. "Shaping the activity of Listeria monocytogenes rhamnosyltransferase RmlT as an auspicious antivirulence strategy.". Paper presented in 8th I3S Annual Meeting (Póvoa de Varzim, Portugal), 2019.
  4. Cereija, T.B.; Alarico, S.; Lourenço, E.C.; Ventura, M.R.; Empadinhas, N.; Pereira, P.J.B.. "Biochemical and structural characterization of a mycobacterial glucosylglycerate hydrolase, a key enzyme in nitrogen starvation recovery". Paper presented in XIX National Congress of Biochemistry (Guimarães, Portugal), 2016.
  5. Cereija, T.B.; Lourenço, E.C.; Ventura, M.R.; Empadinhas, N.; Pereira, P.J.B.. "Structural characterization of a mycobacterial glucosylglycerate hydrolase, a key enzyme in nitrogen starvation recovery". Paper presented in 5th I3S Annual Meeting (Póvoa de Varzim, Portugal), 2016.
  6. Ferreira, C.; Salvador, A. F.; Cereija, T.B.; Cerca, N.; Sousa, D.. "Comparison of vaginal microbiota fingerprints from healthy and bacterial vaginosis-positive portuguese women". Paper presented in MicroBiotec 2013 (Aveiro, Portugal), 2013.
  7. Cereija, T.B.; Machado, A.; Felgueiras, C.; Cerca, N.; Rodrigues, L. R.. "Lactobacilli and its metabolites as potential probiotics against Gardnerella vaginalis". Paper presented in BioMicroWorld 2013 - V International Conference on Environmental, Industrial and Applied Microbiology (Madrid, Spain)., 2013.
  8. Alves, P.; Castro, J.; Sousa, C.; Cereija, T.B.; Cerca, N.. "Gardnerella vaginalis virulence potential outcompetes with 30 other microorganisms isolated from BV patients". Paper presented in Eurobiofilms 2013 (Ghent, Belgium), 2013.
  9. Castro, J.; Alves, P.; Sousa, C.; Cereija, T.B.; Cerca, N.. "Isolation of Gardnerella vaginalis from BV patients and healthy women : analysis of virulence through adherence, biofilm formation and cytotoxicity assays". Paper presented in Eurobiofilms 2013 (Ghent, Belgium), 2013.
  10. Alves, P.; Castro, J.; Cereija, T.B.; Henriques, A.; Cerca, N.. "Characterization of biofilm-forming microorganisms isolated from vaginal exudate in Portugal". Paper presented in Biofilms 5 (Paris, France), 2012.
  11. Freitas, S.C.; Cereija, T.B.; Figueiredo, A.C.; Pereira, P.J.B.; Barbosa, M.A.; Martins, M.C.L.. "Bioengineered surfaces for direct thrombin inactivation to improve their hemocompatibility". Paper presented in 2nd I3S Scientific Retreat (Póvoa de Varzim, Portugal), 2011.
  12. Cereija, T.B.; Figueiredo, A.C.; Macedo-Ribeiro, S.; Fuentes-Prior, P.; Tanaka, A.S.; Pereira, P.J.B.. "Boophilin: one inhibitor and two inhibition mechanisms". Paper presented in XVII National Congress of Biochemistry (Porto, Portugal), 2010.
    10.18638/scieconf.2016.4.1.375
Journal article
  1. Cereija, T.B.; Guerra, J.P.L.; Jorge, J.M.P.; Morais-Cabral, J.H.. "c-di-AMP, a likely master regulator of bacterial K+ homeostasis machinery, activates a K+ exporter". Proceedings of the National Academy of Sciences of the United States of America 118 14 (2021): e2020653118.
    Published • 10.1073/pnas.2020653118
  2. Cereija, T.B.; Alarico, S.; Lourenço, E.C.; Manso, J.A.; Ventura, M.R.; Empadinhas, N.; Macedo-Ribeiro, S.; Pereira, P.J.B.. "The structural characterization of a glucosylglycerate hydrolase provides insights into the molecular mechanism of mycobacterial recovery from nitrogen starvation". IUCrJ 6 4 (2019): 572-585.
    Published • 10.1107/s2052252519005372
  3. Cereija, T.B.; Alarico, S.; Empadinhas, N.; Pereira, P.J.B.. "Production, crystallization and structure determination of a mycobacterial glucosylglycerate hydrolase". Acta Crystallographica Section F Structural Biology Communications 73 9 (2017): 536-540.
    Published • 10.1107/S2053230X17012419
  4. Machado, A.; Castro, J.; Cereija, T.; Almeida, C.; Cerca, N.. "Diagnosis of bacterial vaginosis by a new multiplex peptide nucleic acid fluorescence in situ hybridization method". PeerJ 2015 2 (2015):
    10.7717/peerj.780
  5. Castro, J.; Alves, P.; Sousa, C.; Cereija, T.; França, Â.; Jefferson, K.K.; Cerca, N.. "Using an in-vitro biofilm model to assess the virulence potential of Bacterial Vaginosis or non-Bacterial Vaginosis Gardnerella vaginalis isolates". Scientific Reports 5 (2015):
    10.1038/srep11640
  6. Silva, D.; Henriques, A.; Cereija, T.; Martinez-De-Oliveira, J.; Miranda, M.; Cerca, N.. "Prevalence of Gardnerella vaginalis and Atopobium vaginae in Portuguese women and association with risk factors for bacterial vaginosis". International Journal of Gynecology and Obstetrics 124 2 (2014): 178-179.
    10.1016/j.ijgo.2013.08.008
  7. Alves, P.; Castro, J.; Sousa, C.; Cereija, T.B.; Cerca, N.. "Gardnerella vaginalis Outcompetes 29 other bacterial species isolated from patients with bacterial vaginosis, using in an in vitro biofilm formation model". Journal of Infectious Diseases 210 4 (2014): 593-596.
    10.1093/infdis/jiu131
  8. Cereija, T.B.; Castro, J.; Alves, P.; Cerca, N.. "Influence of anaerobic conditions on vaginal microbiota recovery from bacterial vaginosis patients". Sexually Transmitted Infections 89 4 (2013):
    10.1136/sextrans-2013-051100
  9. Figueiredo, A.C.; De Sanctis, D.; Gutiérrez-Gallego, R.; Cereija, T.B.; Macedo-Ribeiro, S.; Fuentes-Prior, P.; Pereira, P.J.B.. "Unique thrombin inhibition mechanism by anophelin, an anticoagulant from the malaria vector". Proceedings of the National Academy of Sciences of the United States of America 109 52 (2012):
    Published • 10.1073/pnas.1211614109
  10. Henriques, A.; Cereija, T.; Machado, A.; Cerca, N.. "In silico vs in vitro analysis of primer specificity for the detection of Gardnerella vaginalis, Atopobium vaginae and Lactobacillus spp". BMC Research Notes 5 (2012):
    10.1186/1756-0500-5-637
  11. Cereija, T.B.; Figueiredo, A.C.; De Sanctis, D.; Tanaka, A.S.; Pereira, P.J.B.. "Crystallization and preliminary crystallographic characterization of the N-terminal Kunitz domain of boophilin". Acta Crystallographica Section F: Structural Biology and Crystallization Communications 68 4 (2012): 436-439.
    10.1107/S1744309112005532
  12. Freitas, S.C.; Cereija, T.B.; Figueiredo, A.C.; Osório, H.; Pereira, P.J.B.; Barbosa, M.A.; Martins, M.C.L.. "Bioengineered surfaces to improve the blood compatibility of biomaterials through direct thrombin inactivation". Acta Biomaterialia 8 11 (2012): 4101-4110.
    10.1016/j.actbio.2012.07.020
Preprint
  1. Monteiro, R.; Cereija, T.B.; Pombinho, R.; Sousa, S.; Morais-Cabral, J.H.; Cabanes, D.. "Molecular properties of RmlT, a wall teichoic acid rhamnosyltransferase that modulates Listeria monocytogenes virulence and antibiotic resistance". 2024.
Thesis / Dissertation
  1. Cereija, TB; Cereija, T. "Biochemical and structural characterization of novel mycobacterial drug targets". PhD, Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, 2018.
  2. Cereija, TB; Cereija, T. "Characterization of trypsin inhibition by boophilin". Master, Universidade de Aveiro, 2010.

Other

Dataset
  1. Cereija, T.B.; Morais-Cabral, J.H.. Crystal structure of the apo form of the L. monocytogenes RmlT. 2023.
  2. Cereija, T.B.; Morais-Cabral, J.H.. Crystal structure of the L. monocytogenes RmlT in complex with HEPES. 2023.
  3. Cereija, T.B.; Morais-Cabral, J.H.. Crystal structure of the L. monocytogenes RmlT in complex with UDP-glucose. 2023.
  4. Cereija, T.B.; Morais-Cabral, J.H.. Crystal structure of the L. monocytogenes RmlT in complex with TDP-rhamnose. 2023.
  5. Cereija, T.B.; Morais-Cabral, J.H.. Crystal structure of the L. monocytogenes RmlT D198A variant in complex with TDP-rhamnose. 2023.
  6. Cereija, T.B.; Guerra, J.P.L.; Morais-Cabral, J.H.. High-resolution structure of the K+/H+ antiporter subunit KhtT in complex with c-di-AMP. 2021.
  7. Cereija, T.B.; Guerra, J.P.L.; Morais-Cabral, J.H.. Low-resolution structure of the K+/H+ antiporter subunit KhtT in complex with c-di-AMP. 2021.
  8. Cereija, T.B.; Morais-Cabral, J.H.. Structure of the N-domain of the K+/H+ antiporter subunit KhtT at pH 6.5. 2021.
  9. Cereija, T.B.; Morais-Cabral, J.H.. Structure of the N-domain of the K+/H+ antiporter subunit KhtT at pH 8.5. 2021.
  10. Cereija, T.B.; Morais-Cabral, J.H.. Structure of the N-domain of the K+/H+ antiporter subunit KhtT at pH 7.5. 2021.
  11. Cereija, T.B.; Vilela, F.; Macedo-Ribeiro, S.; Pereira, P.J.B.. Mycobacterial hydrolase 1. 2020.
  12. Cereija, T.B.; Vilela, F.; Macedo-Ribeiro, S.; Pereira, P.J.B.. Mycobacterial hydrolase 2. 2020.
  13. Cereija, T.B.; Macedo-Ribeiro, S.; Pereira, P.J.B.. Crystal structure of Mycolicibacterium hassiacum glucosylglycerate hydrolase (MhGgH) - apo form. 2019.
  14. Cereija, T.B.; Macedo-Ribeiro, S.; Pereira, P.J.B.. Mycobacterial hydrolase complex 14. 2019.
  15. Cereija, T.B.; Macedo-Ribeiro, S.; Pereira, P.J.B.. Crystal structure of Mycolicibacterium hassiacum glucosylglycerate hydrolase (MhGgH) E419A variant in complex with glucosylglycolate. 2018.
  16. Cereija, T.B.; Macedo-Ribeiro, S.; Pereira, P.J.B.. Crystal structure of Mycolicibacterium hassiacum glucosylglycerate hydrolase (MhGgH) D182A variant in complex with glucosylglycolate. 2018.
  17. Cereija, T.B.; Macedo-Ribeiro, S.; Pereira, P.J.B.. Crystal structure of Mycolicibacterium hassiacum glucosylglycerate hydrolase(MhGgH) E419A variant in complex with glucosylglycerol. 2018.
  18. Cereija, T.B.; Macedo-Ribeiro, S.; Pereira, P.J.B.. Crystal structure of Mycolicibacterium hassiacum glucosylglycerate hydrolase (MhGgH) E419A variant in complex with mannosylglycerate. 2018.
  19. Cereija, T.B.; Macedo-Ribeiro, S.; Pereira, P.J.B.. Crystal structure of Mycolicibacterium hassiacum glucosylglycerate hydrolase (MhGgH) E419A variant in complex with glucosylglycerate. 2018.
  20. Cereija, T.B.; Macedo-Ribeiro, S.; Pereira, P.J.B.. Crystal structure of Mycolicibacterium hassiacum glucosylglycerate hydrolase (MhGgH) D182A variant in complex with mannosylglycerate. 2018.
  21. Cereija, T.B.; Macedo-Ribeiro, S.; Pereira, P.J.B.. Crystal structure of Mycolicibacterium hassiacum glucosylglycerate hydrolase (MhGgH) D182A variant in complex with glucosylglycerate. 2018.
  22. Cereija, T.B.; Macedo-Ribeiro, S.; Pereira, P.J.B.. Crystal structure of Mycolicibacterium hassiacum glucosylglycerate hydrolase (MhGgH) D43A variant in complex with serine and glycerol. 2018.
  23. Cereija, T.B.; Macedo-Ribeiro, S.; Pereira, P.J.B.. Crystal structure of Mycolicibacterium hassiacum glucosylglycerate hydrolase (MhGgH) E419A variant in complex with serine and glycerol. 2018.
  24. Cereija, T.B.; Macedo-Ribeiro, S.; Pereira, P.J.B.. Crystal structure of Mycolicibacterium hassiacum glucosylglycerate hydrolase (MhGgH) D182A variant in complex with serine and glycerol. 2018.
  25. Cereija, T.B.; Macedo-Ribeiro, S.; Pereira, P.J.B.. Crystal structure of Mycolicibacterium hassiacum glucosylglycerate hydrolase (MhGgH) in complex with serine and glycerol. 2018.
  26. Cereija, T.B.; Macedo-Ribeiro, S.; Pereira, P.J.B.. Crystal structure of Mycolicibacterium hassiacum glucosylglycerate hydrolase (MhGgH) - SeMet derivative. 2018.
  27. Cereija, T.B.; Macedo-Ribeiro, S.; Pereira, P.J.B.. Crystal structure of Mycolicibacterium hassiacum glucosylglycerate hydrolase (MhGgH) in complex with glycerol. 2018.
  28. Figueiredo, A.C.; de Sanctis, D.; Gutiérrez-Gallego, R.; Cereija, T.B.; Macedo-Ribeiro, S.; Fuentes-Prior, P.; Pereira, P.J.B.. Anophelin from the malaria vector inhibits thrombin through a novel reverse-binding mechanism. 2012.
  29. Figueiredo, A.C.; de Sanctis, D.; Gutiérrez-Gallego, R.; Cereija, T.B.; Macedo-Ribeiro, S.; Fuentes-Prior, P.; Pereira, P.J.B.. Anophelin from the malaria vector inhibits thrombin through a novel reverse-binding mechanism. 2012.
Activities

Conference scientific committee

Conference name Conference host
2020 - 2020 3rd PhDay | Back to the Future Universidade do Porto Instituto de Investigação e Inovação em Saúde
Distinctions

Award

2022 Prémio Jovem Biofísico SPBf 2022
Sociedade Portuguesa de Biofísica, Portugal
2022 EMBO Scientific Exchange Grant
European Molecular Biology Organization (EMBO), Germany
2021 Concurso Estímulo ao Emprego Científico Individual (CEEC)
Fundação para a Ciência e a Tecnologia, Portugal
2013 FCT Individual PhD studentship
Fundação para a Ciência e a Tecnologia, Portugal