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Cláudia Saraiva was granted a PhD in Bioengineering (MIT-Portugal) from the New University of Lisbon. During her thesis, she used microRNA-loaded nanoparticles (miR-NP) as therapeutic agents to promote neuronal differentiation of neural stem cells and consequently ameliorate brain damage in Parkinson’s disease (PD) and stroke models. Her PhD project provided evidence supporting miR-124 NP as positive modulators of endogenous neurogenesis and their potential application in brain repair strategies. This work was developed at the Health Science Research Center (CICS), University of Beira Interior, Covilhã, Portugal under the supervision of Dr. Liliana Bernardino and co-supervision of Dr. Lino Ferreira, two leading investigators in the fields of neural stem cells and biomaterials. Part of the PhD work regarding stroke was developed at the Laboratory for Experimental Brain Research, Wallenberg Neuroscience Center, Lund University under the supervision of Dr. Karsten Ruscher. After, she joined Prof. Jens Schwamborn lab at the Luxembourg Centre for System Biomedicine, where she contributed to the further development of human iPSC-derived organoids to model PD (e.g. immunocompetent midbrain organoids) as well as for the phenotypic characterization of familial PD using patient-specific iPSC-derived midbrain organoids. During this period, Cláudia was the lead scientist (PI) on a funded project that used human midbrain organoids derived from iPSCs from PD patients to disclose the role of the Miro1 protein on PD pathology, namely in terms of mitochondria dysfunctional and dopaminergic neuron degeneration. Cláudia aims to continually grow her expertise in the stem cell field and contribute to a better understanding of PD pathology as well as in the development of 3D brain models.
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Identificação

Identificação pessoal

Nome completo
Cláudia Marisa Monteiro Saraiva

Nomes de citação

  • Saraiva, Cláudia

Identificadores de autor

Ciência ID
C215-78E6-FCC3
ORCID iD
0000-0003-4866-8790

Endereços de correio eletrónico

  • c.m.m.saraiva@gmail.com (Pessoal)

Moradas

  • 9, Rue de Luxembourg, L-4220, Esch-sur-Alzette, Esch-sur-Alzette, Luxemburgo (Pessoal)

Websites

Domínios de atuação

  • Ciências Médicas e da Saúde - Medicina Básica - Neurociências

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador independente (B2) Utilizador independente (B2) Utilizador independente (B2) Utilizador proficiente (C1) Utilizador independente (B2)
Francês Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1)
Formação
Grau Classificação
2023/07/07 - 2023/07/11
Concluído
 The International Summer School on Knowledge-Driven Innovation & Entrepreneurship (Postgraduate Certificate)
University of Luxembourg Incubator, Luxemburgo
2022/07/12 - 2022/07/15
Concluído
 The METABOLOMICS Summer School (Postgraduate Certificate)
Universiteit Leiden, Países Baixos
2020/09 - 2020/12
Frequentou
 University of Luxembourg Leadership Academy (ULLA) (Curso médio)
Université du Luxembourg, Luxemburgo
2020/05/01 - 2020/05/31
Concluído
 R tidyverse course (Postgraduate Certificate)
Université du Luxembourg, Luxemburgo
2020/03/05 - 2020/03/06
Concluído
 Leadership Skills for Women in Science (Curso médio)
Université du Luxembourg, Luxemburgo
2012/09/17 - 2017/12/19
Concluído
 Bioengenharia (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
"MicroRNAs-loaded nanoparticles as a new promising therapeutic tool for neural stem cell-based brain repair strategies" (TESE/DISSERTAÇÃO)
 Aprovado por unanimidade
2016/11 - 2016/11
Concluído
 Preclinical Imaging Graduate Course (Curso médio)
Lunds Universitet, Suécia
2016/03 - 2016/03
Concluído
 Laboratory Animal Science for Researchers – Rodents and Lagomorphs, according to FELASA recommendations for category B (Curso médio)
Lunds Universitet, Suécia
2013/11 - 2013/11
Concluído
 1st Hands-On Course on Fluorescence Microscopy and Image Analysis (Curso médio)
Universidade da Beira Interior, Portugal
2010/09 - 2012/09
Concluído
 Bioquímica (Mestrado integrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Development of lipoplex formulations for specific genetic material delivery to pancreatic cancer cells" (TESE/DISSERTAÇÃO)
 18
2007/09 - 2010/06
Concluído
 Bioquímica (Licenciatura)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"n/a" (TESE/DISSERTAÇÃO)
 17
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2019/06/01 - 2023/11/30 Pós-doutorado (Investigação) Université du Luxembourg, Luxemburgo
Université du Luxembourg Luxembourg Centre for Systems Biomedicine, Luxemburgo
2018/09/10 - 2019/05/31 Pós-doutorado (Investigação) Universidade da Beira Interior, Portugal
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2018/09/15 - 2018/12/20 Investigador visitante (Investigação) Universidade da Beira Interior, Portugal
Université du Luxembourg Luxembourg Centre for Systems Biomedicine, Luxemburgo
2017/06/05 - 2018/09/09 Investigador (Investigação) Universidade da Beira Interior, Portugal
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal

Outros

Categoria Profissional
Instituição de acolhimento 		Empregador
2012/09 - 2017/12 PhD Student (doctoral program) Massachusetts Institute of Technology MIT Portugal Program, Portugal
Universidade Nova de Lisboa, Portugal
2013/02 - 2017 PhD Student Fundação para a Ciência e Tecnologia, FCT, Portugal
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2016/05/01 - 2016/12/31 Visiting PhD student Fundação para a Ciência e Tecnologia, FCT, Portugal
Lunds universitet Wallenberg Neuroscience Center, Suécia
Projetos

Bolsa

Designação Financiadores
2023/07/01 - 2023/11/30 National Centre for Excellence in Research on Parkinson’s Disease: From biomarkers to molecular mechanisms
FNR/NCER13/BM/11264123
Bolseiro de Pós-Doutoramento
Université du Luxembourg Luxembourg Centre for Systems Biomedicine, Luxemburgo
 Luxembourg National Research Fund
Concluído
2020/04 - 2023/03/31 Axonal dying-back in Parkinson’s disease is caused by local axonal accumulations of defective mitochondria
C19/BM/13535609
Investigador responsável
Université du Luxembourg Luxembourg Centre for Systems Biomedicine, Luxemburgo
 Fonds National de la Recherche
Em curso
2019/06/01 - 2020/03/31 SysMedPD – Systems Medicine of Mitochondrial Parkinson’s Disease
668738
Bolseiro de Pós-Doutoramento
Université du Luxembourg Luxembourg Centre for Systems Biomedicine, Luxemburgo
 European Union
Concluído
2017/06/05 - 2019/05/31 Desafios interdisciplinares em Neurodegeneração (ICON; Interdisciplinary Challenges On Neurodegeneration
CENTRO-01-0145-FEDER-000013
Bolseiro de Pós-Doutoramento
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
 European Regional Development Fund
Concluído
2013/02/01 - 2017/01/31 MicroRNAs-loaded nanoparticles as a new promising therapeutic tool for neural stem cell-based brain repair strategies
SFRH/BD/90365/2012
Bolseiro de Doutoramento
Universidade Nova de Lisboa, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído

Projeto

Designação Financiadores
2019/01/01 - 2019/12/31 Health Sciences Research Centre
UID/Multi/00709/2019
Universidade da Beira Interior, Portugal

Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2014 - 2015 MicroRNA-124 loaded nanoparticles: boosting neurogenesis to treat Parkinson's disease
EXPL/BIM-MED/0822/2013
Investigador
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
 Fundação para a Ciência e Tecnologia, FCT
Concluído

Outro

Designação Financiadores
2023/03/01 - 2023/11/30 Unveiling novel deregulated Parkinson’s disease-associated pathways using a multi-modal data network-based analysis
NA
Co-Investigador Responsável (Co-IR)
Université du Luxembourg Luxembourg Centre for Systems Biomedicine, Luxemburgo
 Université du Luxembourg Luxembourg Centre for Systems Biomedicine
Em curso
Produções

Publicações

Artigo em revista
  1. Barmpa K; Saraiva C; Diego Lopez-Pigozzi; Gomez-Giro G; Elisa Gabassi; Spitz S; Brandauer K; et al. "Modeling early phenotypes of Parkinson's disease by age-induced midbrain-striatum assembloids.". Communications biology (2024): https://doi.org/10.1038/s42003-024-07273-4.
    10.1038/s42003-024-07273-4
  2. Isabel Rosety; Alise Zagare; Claudia Saraiva; Sarah Nickels; Paul Antony; Catarina Almeida; Enrico Glaab; et al. "Impaired neuron differentiation in GBA-associated Parkinson’s disease is linked to cell cycle defects in organoids". npj Parkinson's Disease (2023): https://doi.org/10.1038/s41531-023-00616-8.
    10.1038/s41531-023-00616-8
  3. Cláudia Saraiva; Jéssica Lopes-Nunes; Marta Esteves; Tiago Santos; Ana Vale; Ana Clara Cristóvão; Raquel Ferreira; Liliana Bernardino. "CtBP Neuroprotective Role in Toxin-Based Parkinson’s Disease Models: From Expression Pattern to Dopaminergic Survival". Molecular Neurobiology (2023): http://dx.doi.org/10.1007/s12035-023-03331-w.
    10.1007/s12035-023-03331-w
  4. Axel Chemla; Giuseppe Arena; Claudia Saraiva; Clara Berenguer-Escuder; Dajana Grossmann; Anne Grünewald; Christine Klein; et al. "Generation of two induced pluripotent stem cell lines and the corresponding isogenic controls from Parkinson’s disease patients carrying the heterozygous mutations c.1290A > G (p.T351A) or c.2067A > G (p.T610A) in the RHOT1 gene encoding Miro1". Stem Cell Research (2023): http://dx.doi.org/10.1016/j.scr.2023.103085.
    10.1016/j.scr.2023.103085
  5. Rebelo, C.; Reis, T.; Guedes, J.; Saraiva, C.; Rodrigues, A.F.; Simões, S.; Bernardino, L.; et al. "Author Correction: Efficient spatially targeted gene editing using a near-infrared activatable protein-conjugated nanoparticle for brain applications (Nature Communications, (2022), 13, 1, (4135), 10.1038/s41467-022-31791-6)". Nature Communications 14 1 (2023): http://www.scopus.com/inward/record.url?eid=2-s2.0-85165234788&partnerID=MN8TOARS.
    10.1038/s41467-023-39976-3
  6. Marta Esteves; Ricardo Abreu; Hugo Fernandes; Catarina Serra-Almeida; Patrícia A.T. Martins; Marta Barão; Ana Clara Cristóvão; et al. "MicroRNA-124-3p-enriched small extracellular vesicles as a therapeutic approach for Parkinson’s disease". Molecular Therapy (2022): http://dx.doi.org/10.1016/j.ymthe.2022.06.003.
    10.1016/j.ymthe.2022.06.003
  7. Catarina Rebelo; Tiago Reis; Guedes, JR; Cláudia Saraiva; Artur Filipe Rodrigues; Susana Simões; Liliana Bernardino; et al. "Efficient spatially targeted gene editing using a near-infrared activatable protein-conjugated nanoparticle for brain applications". Nature Communications (2022): http://dx.doi.org/10.1038/s41467-022-31791-6.
    10.1038/s41467-022-31791-6
  8. Beatriz Garcia Santa Cruz; Jan Slter; Gemma Gomez-Giro; Claudia Saraiva; Sonia Sabate-Soler; Jennifer Modamio; Kyriaki Barmpa; et al. "Generalising from conventional pipelines using deep learning in high-throughput screening workflows". Scientific Reports (2022): http://dx.doi.org/10.1038/s41598-022-15623-7.
    10.1038/s41598-022-15623-7
  9. Sonia Sabate-Soler; Sarah Louise Nickels; Cláudia Saraiva; Emanuel Berger; Ugne Dubonyte; Kyriaki Barmpa; Yan Jun Lan; et al. "Microglia integration into human midbrain organoids leads to increased neuronal maturation and functionality". Glia (2022): https://doi.org/10.1002/glia.24167.
    10.1002/glia.24167
  10. "Argonaute-2 protects the neurovascular unit from damage caused by systemic inflammation.". Journal of neuroinflammation (2022): https://europepmc.org/articles/PMC8740421.
    10.1186/s12974-021-02324-7
  11. Javier Jarazo; Kyriaki Barmpa; Jennifer Modamio; Cláudia Saraiva; Sònia Sabaté-Soler; Isabel Rosety; Anne Griesbeck; et al. "Parkinson's Disease Phenotypes in Patient Neuronal Cultures and Brain Organoids Improved by 2-Hydroxypropyl-ß-Cyclodextrin Treatment". Movement Disorders 37 1 (2022): 80-94. https://doi.org/10.1002/mds.28810.
    10.1002/mds.28810
  12. Iman Zare; Mohammad Tavakkoli Yaraki; Giorgio Speranza; Alireza Hassani Najafabadi; Alireza Shourangiz-Haghighi; Amirala Bakhshian Nik; Bella B. Manshian; et al. "Gold nanostructures: synthesis, properties, and neurological applications". Chemical Society Reviews 51 7 (2022): 2601-2680. https://doi.org/10.1039/D1CS01111A.
    10.1039/D1CS01111A
  13. Saraiva, Cláudia. "New insights into the regulatory roles of microRNAs in adult neurogenesis". Current Opinion in Pharmacology (2020): http://dx.doi.org/10.1016/j.coph.2019.11.003.
    10.1016/j.coph.2019.11.003
  14. Saraiva, Cláudia. "C-Terminal Binding Proteins Promote Neurogenesis and Oligodendrogenesis in the Subventricular Zone.". Frontiers in cell and developmental biology (2020): https://europepmc.org/articles/PMC7815648.
    10.3389/fcell.2020.584220
  15. Saraiva, Cláudia. "Histamine modulates hippocampal inflammation and neurogenesis in adult mice". Scientific Reports (2019): http://dx.doi.org/10.1038/s41598-019-44816-w.
    10.1038/s41598-019-44816-w
  16. Saraiva C; Talhada D; Rai A; Ferreira R; Ferreira L; Bernardino L; Ruscher K. "MicroRNA-124-loaded nanoparticles increase survival and neuronal differentiation of neural stem cells in vitro but do not contribute to stroke outcome in vivo.". PloS one (2018): http://europepmc.org/abstract/med/29494665.
    10.1371/journal.pone.0193609
  17. Saraiva, Cláudia. "Blue light potentiates neurogenesis induced by retinoic acid-loaded responsive nanoparticles.". Acta biomaterialia (2017): http://europepmc.org/abstract/med/28673742.
    10.1016/j.actbio.2017.06.044
  18. Saraiva, Cláudia. "MicroRNA: Basic concepts and implications for regeneration and repair of neurodegenerative diseases.". Biochemical pharmacology (2017): http://europepmc.org/abstract/med/28709951.
    10.1016/j.bcp.2017.07.008
  19. Saraiva C; Praça C; Ferreira R; Santos T; Ferreira L; Bernardino L. "Nanoparticle-mediated brain drug delivery: Overcoming blood-brain barrier to treat neurodegenerative diseases.". (2016): http://europepmc.org/abstract/med/27208862.
    10.1016/j.jconrel.2016.05.044
  20. Saraiva C; Paiva J; Santos T; Ferreira L; Bernardino L. "MicroRNA-124 loaded nanoparticles enhance brain repair in Parkinson's disease.". (2016): http://europepmc.org/abstract/med/27269730.
    10.1016/j.jconrel.2016.06.005
  21. Santos T; Boto C; Saraiva CM; Bernardino L; Ferreira L. "Nanomedicine Approaches to Modulate Neural Stem Cells in Brain Repair.". (2016): http://europepmc.org/abstract/med/26917252.
    10.1016/j.tibtech.2016.02.003
  22. Rocha SM; Saraiva T; Cristóvão AC; Ferreira R; Santos T; Esteves M; Saraiva C; et al. "Histamine induces microglia activation and dopaminergic neuronal toxicity via H1 receptor activation.". (2016): http://europepmc.org/abstract/med/27260166.
    10.1186/s12974-016-0600-0
  23. Saraiva C; Ferreira L; Bernardino L. "Traceable microRNA-124 loaded nanoparticles as a new promising therapeutic tool for Parkinson's disease.". (2016): http://europepmc.org/abstract/med/28405588.
    10.1080/23262133.2016.1256855
Capítulo de livro
  1. Saraiva, C.; Santos, T.; Bernardino, L.. "Neural stem cell-based therapeutic approaches for brain repair". 241-252. 2018.
Edição de número de revista
  1. Ferreira, Raquel; Liliana Bernardino; Saraiva, Cláudia. "Stem cells & brain injury: reprogramming, modeling and therapy". Frontiers in Cellular Neuroscience (2022):
    Editor convidado
Pré-impressão
  1. Alise Zagare; Irina Balaur; Adrien Rougny; Claudia Saraiva; Matthieu Gobin; Anna S. Monzel; Soumyabrata Ghosh; Venkata P. Satagopam; Jens C. Schwamborn. "Deciphering shared molecular dysregulation across Parkinson’s Disease variants using a multi-modal network-based data integration and analysis". 2024. https://doi.org/10.1101/2024.09.30.615801.
    10.1101/2024.09.30.615801
  2. Axel Chemla; Giuseppe Arena; GINEVRA SACRIPANTI; Kyriaki Barmpa; Alise Zagare; Pierre GARCIA; P.M.A. Antony; et al. "Parkinson’s disease-related Miro1 mutation induces mitochondrial dysfunction and loss of dopaminergic neuronsin vitroandin vivo". 2023. http://dx.doi.org/10.1101/2023.12.19.571978.
    10.1101/2023.12.19.571978
  3. Kyriaki Barmpa; Claudia Saraiva; Gemma Gomez-Giro; Elisa Gabassi; Sarah Spitz; Konstanze Brandauer; Juan Eduardo Rodriguez Gatica; et al. "Age-induced midbrain-striatum assembloids model early phenotypes of Parkinson’s disease". 2023. http://dx.doi.org/10.1101/2023.10.28.564305.
    10.1101/2023.10.28.564305
  4. Jennifer Modamio; Claudia Saraiva; Gemma Gomez Giro; Sarah Louise Nickels; Javier Jarazo; Paul Antony; Peter Barbuti; et al. "Synaptic decline precedes dopaminergic neuronal loss in human midbrain organoids harboring a triplication of the SNCA gene". 2021. http://dx.doi.org/10.1101/2021.07.15.452499.
    10.1101/2021.07.15.452499
Tese / Dissertação
  1. "MicroRNA-124-loaded nanoparticles as a new promising therapeutic tool for neural stem cell-based brain repair strategies". Doutoramento, Universidade Nova de Lisboa, 2017.
  2. "Development of Lipoplex Formulations for Specific Genetic Material Delivery to Pancreatic Cancer Cells". Mestrado, Universidade de Coimbra, 2012.

Outros

Conjunto de dados
  1. Axel Chemla; Jochen Ohnmacht; Saraiva, Cláudia; Rejko Krüger. Unveiling the effect of the Parkinson's disease related Miro1R272Q mutation in the transcriptome of human iPSC-derived dopaminergic neurons. https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE238129. 2023.
  2. Alise Zagare; Barmpa, K.; Jens C. Schwamborn; Saraiva, Cláudia. Single cell profile of human iPSC-derived midbrain organoids from healthy individual, Parkinson disease patient harboring a Miro1R272Q mutation and its respective isogenic control. https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE237133. 2023.
Outra produção
  1. Targeting autophagy to identify novel modulators of Parkinson’s disease using midbrain organoids. 2023. Jarazo, J.; Isabel Rosety; Serra-Almeida, C; Marques, R; Saraiva, Cláudia; Davis, R; Schwamborn, J.C.. https://www.mdsabstracts.org/abstract/targeting-autophagy-to-identify-novel-modulators-of-parkinsons-disease-using-midbrain-organoids/.
  2. Microglia integration into human midbrain organoids leads to increased neuronal maturation and functionality. 2022. Sabate-Soler, S.; Nickels, S.L.; Saraiva, C.; Berger, E.; Dubonyte, U.; Barmpa, K.; Lan, Y.J.; et al. http://www.scopus.com/inward/record.url?eid=2-s2.0-85125584006&partnerID=MN8TOARS.
    10.1101/2022.01.21.477192
  3. Generalising from Conventional Pipelines: A Case Study in Deep Learning-Based for High-Throughput Screening. 2021. Cruz, B.G.S.; Sölter, J.; Giro, G.G.; Saraiva, C.; Sabaté-Soler, S.; Modamio, J.; Barmpa, K.; et al. http://www.scopus.com/inward/record.url?eid=2-s2.0-85168030858&partnerID=MN8TOARS.
    10.21203/rs.3.rs-991404/v1
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2024/10/17 Parkinson’s disease-associated mutation in Miro1 leads to mitochondrial dysfunction and dopaminergic neuron degeneration 3rd Clinical Genetics
French-speaking Association of Clinical Genetics (AFGC)
2022/11 Parkinson’s disease-associated mutation in Miro1 leads to mitochondrial impairments and dopaminergic neuron degeneration Neuroscience 2022
(San Diego, Estados Unidos)
2022/10 REMODEL Summer School India EMBO Lecture Course Microphysiological Systems
CSIR–Indian Institute Of Chemical Technology (Hyderabad, Índia)
2022/09 Midbrain organoids for Parkinson’s Disease modeling REMODEL Summer School
i3s (Porto, Portugal)
2022/06 Midbrain organoids for Parkinson’s Disease modeling SelectBIO, 2022
(Rotterdam, Países Baixos)
2021/11 Miro1 mutant midbrain organoids show mitochondrial dysfunction and dopaminergic neuron loss 50 Annual Meeting of the Society for Neuroscience
Society for Neuroscience (Virtual)
2018 Neural stem cell-based strategies to promote brain repair UBI University Lunch Seminar CICS-UBI
Health Sciences Research Center, University of Beira Interior (Covilhã, Portugal)
2018 Potential therapeutic effect of microRNA-124-loaded nanoparticles in ischemic stroke Portuguese Society of Pharmacology (SPF) Meeting
Portuguese Society of Pharmacology (Lisboa, Portugal)
2015 MicroRNA-loaded nanoparticles induce subventricular zone neurogenesis in a mouse model for Parkinson's disease 9th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies
Portuguese Society for Stem Cells and Cell Therapies (Oeiras, Portugal)
2015 MicroRNA-loaded nanoparticles as modulators of neurogenesis in the subventricular zone X Annual CICS symposium,
Health Sciences Research Center, University of Beira Interior (Covilhã, Portugal)
2015 Modulation of neural stem cells from the subventricular zone by microRNA-loaded nanoparticle Portuguese Society of Pharmacology (SPF) Meeting
Portuguese Society of Pharmacology (Lisboa, Portugal)
2014/11 MicroRNA-124 loaded nanoparticles modulate neurogenesis in the subventricular zone 44th annual Meeting of Society for Neuroscience
Society for Neuroscience (Washington, Estados Unidos)
2014 MicroRNA-124 loaded nanoparticles modulate neurogenesis in the subventricular zone Portuguese Society of Pharmacology (SPF) Meeting
Portuguese Society of Pharmacology (Coimbra, Portugal)

Orientação

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2017/09 - 2018/06 The role of novel transcriptional regulation mechanisms in neurogenesis
Coorientador
Universidade da Beira Interior, Portugal

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação) 		Instituição / Organização
2018 - 2018 International advanced course “Translational approaches for regenerative-based therapies.” (2018/11/29 - 2018/11/30)
Conferência (Membro da Comissão Organizadora)
2014 - 2018 Semana Internacional do Cérebro (Brain Awareness Week, Dana Foundation) (2014 - 2018)
Outro (Membro da Comissão Organizadora)
 Universidade da Beira Interior, Portugal
2017 - 2017 10th International Meeting of Portuguese Society for Stem Cells and Cell Therapies (SPCE-TC) (2017/10/12 - 2017/10/14)
Conferência (Membro da Comissão Organizadora)
 Universidade da Beira Interior, Portugal

Participação em evento

Descrição da atividade
Tipo de evento 		Nome do evento
Instituição / Organização
2022 - Atual Volunteer as a scientist in the initiative Cartas com Ciência - programs of letter exchanges between scientists and students in Portuguese-speaking countries Cartas com Ciência
2019 - 2019 Participation in Luxembourg Centre for System Biomedicine 10-year celebration event called “Family Day” – Laboratory Tour for Families 10-year celebration
Université du Luxembourg Luxembourg Centre for Systems Biomedicine, Luxemburgo
2018 - 2018 Recreational-pedagogical activities (lectures and yoga sessions) about the impact of stress on the brain. Brain Awareness Week
Universidade da Beira Interior, Portugal
2016 - 2016 Recreational-pedagogical activities related to brain function associated with music. Activities with 4 years-old children were done as well as a session dedicated to music for parents and babies Brain Awareness Week
Universidade da Beira Interior, Portugal
2015 - 2015 recreational-pedagogical activities on aspects related to active and healthy aging followed by a visit to the Health Science Research Centre laboratories (March 26th), University of Beira Interior. Playful pedagogical activities on the development of a healthy brain (Dr. José Dinis da Fonseca Regional School, Guarda, Portugal) Brain Awareness Week
Universidade da Beira Interior, Portugal
2014 - 2014 Recreational-pedagogical activities on how the brain works for grandparents and grandchildren to stimulate memory and dexterity Brain Awareness Week
Universidade da Beira Interior, Portugal

Arbitragem científica em conferência

Nome da conferência Local da conferência
2019 - 2019 III International Congress in Health Sciences Research. Towards Innovation and Entrepreneurship: Trends in Aging and Cancer University of Beira Interior

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2023/09 - 2033/09 Master in Integrated Systems Biology Molecular Medicine I (Master) Université du Luxembourg, Luxemburgo
2022/10 - 2022/10 EMBO Lecture Course Microphysiological Systems: Advances and applications in human-relevant research midbrain organoids CSIR–Indian Institute Of Chemical Technology, Índia
2022/09 - 2022/09 Master in Integrated Systems Biology Molecular Medicine I (Master) Université du Luxembourg, Luxemburgo
2022/09 - 2022/09 REMODEL Summer School: Next-Generation Organoids and organ-on-chip Organoids and organ-on-chip Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2021/09/20 - 2021/10/04 Master in Integrated Systems Biology Molecular Medicine I (Master) Université du Luxembourg, Luxemburgo
2020/09/14 - 2020/09/25 Master in Integrated Systems Biology Molecular Medicine I (Master) Université du Luxembourg, Luxemburgo
2019/09/26 - 2019/09/27 MASTER IN INTEGRATED SYSTEMS BIOLOGY MOLECULAR MEDICINE I (Master) Université du Luxembourg, Luxemburgo
2018/11/29 - 2019/03/01 Terapias Regenerativas Curso Avançado Terapias Regenerativas (Outros) Universidade da Beira Interior, Portugal

Membro de associação

Nome da associação Tipo de participação
2021 - Atual Society for Neuroscience
2013 - Atual Sociedade Portuguesa de Neurociências
2022/01/01 - 2023/12/31 Society for Neuroscience member

Outro júri / avaliação

Descrição da atividade Instituição / Organização
2018 - 2019 Biomedical Sciences Bachelor project “Nanotubos de Carbono na Biomedicina: da sua produção à entrega de fármacos” from André Filipe Miranda Universidade da Beira Interior, Portugal
2018 - 2019 Biomedical Sciences Bachelor project “Utilização de scaffolds para regeneração neural com ênfase na técnica de electrospinning” from Andreia Liliane Louro Universidade da Beira Interior, Portugal

Revisão ad hoc de artigos em revista

Nome da revista (ISSN) Editora
2024 - Atual Journal of Molecular Pathology (MDPI) (2673-5261)
2024 - Atual Jornal de Investigação Médica (Ponteditora) (2184-7509)
2023 - Atual Frontiers in Genetics (Frontiers) (1664-8021)
2023 - Atual Frontiers in Cellular Neuroscience (Frontiers) (1662-5102)
2022 - Atual Frontiers in Aging Neuroscience (Frontiers) (1663-4365)
2020 - Atual Matter (Cell Press) (2590-2385)
2019 - Atual STAR Protocols (Cell Press) (26661667)

Tutoria

Tópico Nome do aluno
2022/04/01 - 2033/03/31 Technician at Axonal dying-back in Parkinson’s disease is caused by local axonal accumulations of defective mitochondria (CD19/BM/13535609) Raquel Forte Marques
2020/12/01 - 2023/10/03 Enhancing the Complexity of 3D In Vitro Models for Parkinson's Disease Research Kyriaky Barmpa
2018/03/01 - 2022/03/22 Increasing the complexity of midbrain organoid systems for developmental studies and disease modelling Sònia Sabaté Soler
2020/08/01 - 2021/12/31 Technician at Axonal dying-back in Parkinson’s disease is caused by local axonal accumulations of defective mitochondria (CD19/BM/13535609) Ginevra Sacripanti
Distinções

Prémio

2021 SfN Trainee Professional Development Award (TPDA)
Society for Neuroscience, Estados Unidos
2019 Marie Sklodowska-Curie Individual fellowship (H2020-MSCA-IF-2019), project: “Accumulation of defective mitochondria in axons: cause of neurodegeneration in Parkinson’s disease?” ID 886006 - declined in favor of the CORE Junior grant (CD19/BM/13535609)
European Commission Marie Sklodowska-Curie Actions, Bélgica
2019 Rapid Incentive Scheme (RISE) grant
Université du Luxembourg, Luxemburgo

Outra distinção

2018 Travel grant from FENS-IBRO/PERC
Federation of European Neuroscience Societies, Bélgica
2015 Best PhD student oral communication
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2014 Travel grant to attend the 44th annual meeting of Society for Neuroscience
Fundação Luso-Americana, Portugal
2010 The 3% Best Students Award (MSc in Biochemistry)
Universidade de Coimbra, Portugal
2009 The 3% Best Students Award (BSc in Biochemistry)
Hospitais da Universidade de Coimbra, Portugal
2008 The 3% Best Students Award (BSc in Biochemistry)
Hospitais da Universidade de Coimbra, Portugal
2007 The 3% Best Students Award - BSc in Biochemistry (Entry Grade)
Hospitais da Universidade de Coimbra, Portugal