???global.info.a_carregar???
Henrique Girao (HG) is Principal Investigator and Group Leader (Group of Ubiquitin-dependent proteolysis and Intercellular Communication - GUIC) at the Institute for Clinical and Biomedical Research (iCBR) - Faculty of Medicine of the University of Coimbra (FMUC). HG has been interested in understanding how disturbance of ubiquitin-dependent lysosomal degradation and intercellular communication, mediated by gap junctions and extracellular vesicles, contribute to cardiovascular disorders. HG is the director of iCBR, deputy-director for R&D at FMUC, and coordinator of the Group of Cellular and Translational Cardiology that brings together basic researchers and clinicians at Centre for Innovative Biomedicine and Biotechnology (CIBB-UC). HG integrates the Nucleus of the Working Group on Cellular Biology of the Heart of ESC and the management committee of CARDIOPROTECTION COST action. HG has secured around 1.5 million in 5 FCT funded projects and published 85 papers in peer-reviewed journals including the prestigious Circ Res, Science Advances, Cardiovasc Res, Basic Res Cardiol, Life Sci Alliance, Trends Cell Biol, Trends Mol Med, Autophagy, Molec Cell Proteomics and J Extracell Vesicles. In the last 11 years, as group leader, HG published 50 papers in the fields of intercellular communication, proteolysis and cardiovascular diseases, being 34 of them as last author, with an accumulated impact factor of 426. HG has participated, as invited speaker, in leading national and international scientific conferences in the field of cardiology, gap junctions or proteostasis, including the prestigious EMBO Workshops (2019), International Gap Junction Conference (2017), EU-CARDIOPROTECTION COST WG Meetings (2018-20) and Myocardial Function & Cellular Biology of the Heart Meeting (2017). HG is editor in the international peer-reviewed journals J Extracellular Vesicles, Frontiers in Physiology, Scientific Reports and Portuguese Journal of Cardiology. HG has served has reviewer in reputed journals such as Cardiovascular Research, Autophagy, Journal of Molecular and Cellular Cardiology, and FASEB J. HG coordinates the Master in Biomedical Research and the PhD Programme in Health Sciences and integrates the Scientific Council of the Doctoral Program in Nursing. HG organized >50 advanced courses of MSc and PhD programmes. In the past 5 years, HG supervised/co-supervised 9 PhD Theses (+ 9 ongoing), 34 Master Theses and 9 Posdocs, and integrated the Jury of 29 PhD Defenses (20 as main opponent). HG has launched a Health Communication Laboratory, at the FMUC to promote scientific culture and literacy in the society. In 2015, HG launched the Portuguese network in basic and translational research in cardiology PT_Beat, to foster synergies between Portuguese research groups working on cardiovascular field. Selected Publications: - Ferreira JV et al (2022) Sci Advances (accepted); - Alves-Silva J et al (2022) Pharmacol Res. 2:106151; - van der Velden J et al (2022) Cardiovasc Res. 2022 cvab370; - Lecour S et al (2021) Basic Res Cardiol 116(1):52; - Klionsky DJ et al (2021) Autophagy; - Lissoni A et al (2021) Cardiovasc Res 117(1):123-136; - Perrino C (2021) Cardiovasc Res 117(2):367-385; - Martins-Marques T et al (2020) Circulation Research 126, E97-E113; - Martins-Marques T et al (2020) Life Sci Alliance 3(12); - Martins-Marques T et al (2020) Trends Mol Med S1471-4914(20)30263-X; - Catarino S (2020) Cells 9(4):902; - Martins-Marques T et al (2019) Trends Cell Biol 29(10):835-847; - Almeida-Paiva R et al (2019) J Cel Mol Med 23(2): 1137-1151; - Davidson SM (2019) Cardiovasc Res 1;115(7):1156-1166; - Martins-Marques, T. et al. (2016) J of Extracell Ves 5, 32538; - Soares AR* et al (2015) Sci Rep 5, 13243; - Martins-Marques T et al (2015) Biochemical Journal 467, 231-45
Identificação

Identificação pessoal

Nome completo
Henrique Girao

Nomes de citação

  • Girao, Henrique

Identificadores de autor

Ciência ID
5216-BE64-1B6F
ORCID iD
0000-0002-5786-8447

Domínios de atuação

  • Ciências Naturais - Ciências Biológicas - Biologia Celular

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Espanhol; Castelhano Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Francês Utilizador independente (B1) Utilizador independente (B1) Utilizador elementar (A1) Utilizador independente (B1)
Formação
Grau Classificação
2021/06/22
Concluído
Biomedical Sciences (Título de Agregado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2006
Concluído
Biomedical Sciences (Doutoramento)
Universidade de Coimbra Faculdade de Medicina, Portugal
"Alvos em movimento: Contribuição para o estudo da degradação proteica em sistemas visuais" (TESE/DISSERTAÇÃO)
1998
Concluído
Master in Vision Sciences (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
"Implicações da oxidação do colesterol no desenvolvimento da catarata" (TESE/DISSERTAÇÃO)
1995
Concluído
Biochemistry (Licenciatura)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Oxidação do colesterol em membranas biológicas: o cristalino como modelo funcional" (TESE/DISSERTAÇÃO)
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento
Empregador
2019 - Atual Investigador principal (carreira) (Investigação) Universidade de Coimbra Faculdade de Medicina, Portugal
2008 - 2019 Investigador Auxiliar (carreira) (Investigação) Universidade de Coimbra Faculdade de Medicina, Portugal
2006 - 2008 Pós-doutorado (Investigação) Fundação para a Ciência e a Tecnologia, Portugal
Instituto de Biología Molecular de Barcelona, Espanha

Cargos e Funções

Categoria Profissional
Instituição de acolhimento
Empregador
2015 - Atual Subdirector de Unidade Orgânica Universidade de Coimbra Faculdade de Medicina, Portugal
Universidade de Coimbra Faculdade de Medicina, Portugal

Outros

Categoria Profissional
Instituição de acolhimento
Empregador
2021 - Atual Director Institute for Clinical and Biomedical Research (iCBR), Portugal
Universidade de Coimbra Faculdade de Medicina, Portugal
2012 - Atual Leader of the Group of ubiquitin-dependent proteolysis and intercellular communication (GUIC) Universidade de Coimbra Faculdade de Medicina, Portugal
2003 - 2005 Research Fellowship Universidade de Coimbra Faculdade de Medicina, Portugal
1998 - 2002 PhD Grant Holder Fundação para a Ciência e a Tecnologia, Portugal
Universidade de Coimbra Faculdade de Medicina, Portugal
(...)
1996 - 1998 Master Grant Holder Fundação para a Ciência e a Tecnologia, Portugal
Universidade de Coimbra Faculdade de Medicina, Portugal
Projetos

Bolsa

Designação Financiadores
2022 - Atual ConCOEUR: Unveiling the impact of Connexin43 (Cx43)-mediated gene expression at the crossroads of aortic valve stenosis and left ventricle hypertrophy
EXPL/MED-OUT/0590/2021
Investigador
Fundação para a Ciência e a Tecnologia
2021 - Atual Radiolabeled EXosomes - a nanotheranostic tool for lung micrometastasis in osteosarcoma
PTDC/BTM-SAL/4451/2020
Investigador
Universidade de Coimbra Faculdade de Medicina, Portugal
Fundação para a Ciência e a Tecnologia
2018 - Atual Re-PAIR: A novel mechanism to re-pair HFpEF and endothelial damage
FCT/PT2020-02/SAICT/2017_424
Investigador responsável
Universidade de Coimbra Faculdade de Medicina, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2018 - Atual On the right side: unveiling the mechanisms of pulmonary hypertension reversability and the heart failure progression (Co-PI)
FCT/PT2020 - 02/SAICT/2017_434
Investigador responsável
Universidade de Coimbra Faculdade de Medicina, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2018 - Atual ExoSwitch – Understanding the switch between dry and wet age-related macular degeneration: role of exosomes (Co-PI)
Global Ophthalmology Awards Program from Bayer
Investigador
Em curso
2018 - Atual Speed, crash and run: exersomes boost neuroenergetics and mood in mice on speed (MOOD EXERsomes)
POCI-01-0145-FEDER-030786
Investigador
2017 - Atual Infrastructure of Collection and Disclosure of Health Contents - Laboratory of Communication and Disclosure in Health at FMUC
IRIS
Investigador responsável
Universidade de Coimbra Faculdade de Medicina, Portugal
Em curso
2016 - Atual Integrated Programmes IC&DT - CENTRO-45-2015-01
Healthy Ageing 2020
Investigador responsável
Em curso
2015 - Atual Multidisciplinary Research Institute of Ageing
MIA - TEAMING
Outra
Universidade de Coimbra Faculdade de Medicina, Portugal
Em curso
2015 - Atual Cellular and Molecular Biology of Ageing
ERA-CHAIR@UC
Outra
Universidade de Coimbra Faculdade de Medicina, Portugal
Em curso
2014 - 2016 Aging, Stress and Chronic Diseases
QREN-UC
Outra
2012 - 2015 Unravelling the molecular events of gap junction remodelling in ischemic heart
Investigador responsável
Universidade de Coimbra Faculdade de Medicina, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2012 - 2015 An animal model for age-related changes in proteostasis
Investigador responsável
Fundação para a Ciência e a Tecnologia
Concluído
2014 - 2014 Disruption of intercellular communication in the ischemic heart: exosomes bring the news
GAI_FMUC_HG/2014
Investigador responsável
Concluído
2011 - 2014 Tumorigenesis as a working model for the physiological role of HIF-1alpha degradation by chaperone-mediated autophagy
Investigador responsável
Fundação para a Ciência e a Tecnologia
Concluído
2009 - 2011 Functional genomics studies of phagocytosis in retinal pigment epithelium
PTDC/SAU-GMG/105175/2008
Outra
Fundação para a Ciência e a Tecnologia
Concluído
2006 - 2008 A new route for endothelial dysfunction on diabetes: From phenotypes to molecules
FCT - PTDC/SAU-OSM/67498/2006
Investigador responsável
Fundação para a Ciência e a Tecnologia
Concluído
2005 - 2007 Filling in the GAP: the missing link between intercellular communication and diabetic retinopathy.
FCT - POCI/SAU-MMO/57216/2004
Outra
Fundação para a Ciência e a Tecnologia
Concluído
2002 - 2005 Degradation of GLUT1 by ubiquitin proteasome pathway as a novel regulatory mechanism for glucose transport on diabetic retinopathy
POCTI/MGI/39142/2001
Outra
Fundação para a Ciência e a Tecnologia
Concluído
2002 - 2005 Identification and physiological role of deubiquitinating enzymes in the lens: a novel function for ubiquitin
FCT - POCTI/CBO/39137/2001
Outra
Fundação para a Ciência e a Tecnologia
Concluído
1999 - 2001 Age, diabetes and cataract related changes in ubiquitin - dependent proteolysis in human lens epithelial cells
FCT - PRAXIS XXI
Outra
Fundação para a Ciência e a Tecnologia
Concluído
1997 - 1999 Implications of cholesterol oxidation in Human cataract formation
FCT - PRAXIS XXI
Outra
Fundação para a Ciência e a Tecnologia
1998 - 1998 F2-Isoprostanes as Markers of Oxidative Injury in Human retina
CRUP- British Council B3/98
Outra
Concluído
1993 - 1996 The Role on Cell Membranes in Lens Ageing and Cataract
European concerted actions
Outra
Concluído

Outro

Designação Financiadores
2021 - Atual 'Connex_IN&OUT'
PID: 14677
Investigador responsável
Istruct-ERIC, Bélgica
Produções

Publicações

Artigo em conferência
  1. Sousa, José; Reis, Liliana; Silva, Maria; Lourenço, Carolina; Martins-Marques, Tânia; Girao, Henrique; Gonçalves, Lino. "Circulating exosomal connexin-43 as a potential biomarker for myocardial infarction". Trabalho apresentado em 53rd ESCI2019 Annual Scientific Meeting of the European Society for Clinical Investigation, 2019.
  2. Tânia Martins-Marques; Steve Catarino; Cláudia G. Almeida; Girao, Henrique. "EHD proteins mediate ubiquitin-dependent recycling of gap junctions (GJs) in the ischemic heart". Trabalho apresentado em 53rd ESCI2019 Annual Scientific Meeting of the European Society for Clinical Investigation, 2019.
  3. Tânia Martins-Marques; Steve Catarino; Cláudia G. Almeida; Girao, Henrique. "EHD proteins mediate gap junction (GJ) remodeling during myocardial ischemia". Trabalho apresentado em ESC Congress 2018, 2018.
  4. Montero Bullón, Javier Fernando; Melo, Tania; Martins-Marques, Tania; Girão, Henrique; Domingues, Rosário; Domingues, Pedro. "Alteration of phospholipidome profile in the heart of an animal model of acute myocardial infarction". Trabalho apresentado em Annual SFRR-E Conference 2017 Metabolic Stress and Redox Regulation, 2017.
  5. Santos-Almeida, Fernanda Machado; Meschiari, César A; Martins-Marques, Tânia; Cury-Pavao, Maria L; Salgado, Helio S; Girao, Henrique; Fazan, Rubens. "Acetylcholine Stimulation with Pyridostigmine Prevents Cardiac Arrhythmias in Conscious Myocardial Infarcted Rats and Upregulate Connexin 43, Hypoxic Inducible Factor-1a and Vascular Endothelial Grow Factor in Cardiomyocytes Culture". Trabalho apresentado em American Heart Association's Council on Hypertension 2016, 2016.
  6. Paulo, J.; Balça, J.; Areias, M.; André, L.; Catarino, S.; Zuzarte, M.; Cadime, A.; et al. "Degradation of Connexin43 in the plasma membrane by autophagy in colon cancer". Trabalho apresentado em European Society for Medical Oncology (ESMO) Congress 2015, 2015.
  7. Folques Vicente, J.P.; Balça, J.; Matias, D.; Girão, H.; Sarmento-Ribeiro, A.B.; Nascimento-Costa, J.M.. "Cellular and Molecular Mechanisms of Mechanotransduction Involved in Metastasis - an in Vitro Study in Hepatocarcinoma and Breast Cancer Cell Lines". Trabalho apresentado em European Society for Medical Oncology (ESMO) Congress 2014, 2014.
  8. Martins-Marques, T; Pereira, P; Girao, H. "Degradation of gap junction protein Cx43 by autophagy in ischemic heart is determined by the triggering signal: the role of AMPK Vs Beclin1". Trabalho apresentado em Frontiers in Cardiovascular Biology 2014, 2014.
  9. T. Marques; C. Marques; T. Ribeiro-Rodrigues; P. Matafome; P. Pereira; L. M. Goncalves; H. Girao. "To beat or not to beat: detrimental autophagy contributes to gap junctions degradation in ischemic heart". Trabalho apresentado em ESC Congress, 2013.
  10. T. Rodrigues; C. Marques; T. Marques; P. Matafome; P. Pereira; L. M. Goncalves; H. Girao. "Ubiquitin induces interference in communication: ubiquitination of cx43 leads to gap junction degradation in ischemic heart". Trabalho apresentado em ESC Congress, 2013.
  11. Girao, H.; Marques, C.; Soares, A.; Fernandes, R.; Pereira, P.. "Proteasome dysfunction in retinal pigment epithelium during aging contributes to the pathogenesis of Age-Macular related Degeneration". Trabalho apresentado em EVER 2013, 2013.
  12. Marques, C.; Matafome, P.; Santos, A.; Lobo, C.; Shang, F.; Pereira, P.; Girao, H.. "In vivo analysis of protein quality control in response to aging using transgenic mice". Trabalho apresentado em EVER 2013, 2013.
Artigo em revista
  1. Domingues, Neuza; Gonçalves, Teresa; Girao, Henrique. "Phagolysosomal remodeling to confine C. albicans in macrophage". Trends in Microbiology (2022):
    Aceite para publicação
  2. Alves-Silva, Jorge M.; Zuzarte, Mónica; Marques, Carla; Viana, Sofia; Preguiça, Inês; Baptista, Rui; Ferreira, Cátia; et al. "1,8-cineole Ameliorates Right Ventricle Dysfunction Associated With Pulmonary Arterial Hypertension by Restoring Connexin 43 and Mitochondrial Homeostasis". Pharmacological Research (2022): 106151.
  3. van der Velden, Jolanda; Asselbergs, Folkert W; Bakkers, Jeroen; Batkai, Sandor; Bertrand, Luc; Bezzina, Connie R; Bot, Ilze; et al. "Animal models and animal-free innovations for cardiovascular research: current status and routes to be explored. Consensus document of the ESC Working Group on Myocardial Function and the ESC Working Group on Cellular Biology of the Heart". Cardiovascular Research (2022):
  4. Ferreira JV; Soares, AR; Ramalho, J; Carvalho, CM; Cardoso, MH; Pintado, P; Carvalho, AS; et al. "LAMP2A regulates the loading of proteins into exosomes". Science Advances (2022):
    Aceite para publicação
  5. Abreu, Mónica Teresa; Baptista, Rui; Girão, Henrique. "Immune cell subsets as a marker of development of heart failure: The application of bioinformatics tools". Revista Portuguesa de Cardiologia (English Edition) 40 11 (2021): 849-851.
  6. Lecour, Sandrine; Andreadou, Ioanna; Bøtker, Hans Erik; Davidson, Sean M.; Heusch, Gerd; Ruiz-Meana, Marisol; Schulz, Rainer; et al. "IMproving Preclinical Assessment of Cardioprotective Therapies (IMPACT) criteria: guidelines of the EU-CARDIOPROTECTION COST Action". Basic Research in Cardiology 116 1 (2021):
  7. Montero-Bullon, Javier-Fernando; Aveiro, Susana S.; Melo, Tânia; Martins-Marques, Tânia; Lopes, Diana; Neves, Bruna; Girão, Henrique; Rosário M Domingues, M.; Domingues, Pedro. "Cardiac phospholipidome is altered during ischemia and reperfusion in an ex vivo rat model". Biochemistry and Biophysics Reports 27 (2021): 101037.
  8. Pesce, Maurizio; Agostoni, Piergiuseppe; Bøtker, Hans-Erik; Brundel, Bianca; Davidson, Sean M; Caterina, Raffaele De; Ferdinandy, Peter; et al. "COVID-19-related cardiac complications from clinical evidences to basic mechanisms: opinion paper of the ESC Working Group on Cellular Biology of the Heart". Cardiovascular Research 117 10 (2021): 2148-2160.
  9. Alves-Silva, Jorge M.; Zuzarte, Mónica; Girão, Henrique; Salgueiro, Lígia. "The Role of Essential Oils and Their Main Compounds in the Management of Cardiovascular Disease Risk Factors". Molecules 26 12 (2021): 3506.
  10. Aires, Inês Dinis; Ribeiro-Rodrigues, Teresa; Boia, Raquel; Ferreira-Rodrigues, Magda; Girão, Henrique; Ambrósio, António Francisco; Santiago, Ana Raquel. "Microglial Extracellular Vesicles as Vehicles for Neurodegeneration Spreading". Biomolecules 11 6 (2021): 770.
  11. Martins-Marques, Tania; Rodriguez-Sinovas, Antonio; Girao, Henrique. "Cellular crosstalk in cardioprotection: where and when do reactive oxygen species play a role?". Free Radical Biology and Medicine (2021):
  12. Girão, Henrique; Martins-Marques, Tania. "A novel cardioprotective strategy targeting mitochondrial reactive oxygen species production independent of antioxidant activity (Editorial Comment)". Revista Portuguesa de Cardiologia (2021):
  13. Daniel J. Klionsky; Amal Kamal Abdel-Aziz; Sara Abdelfatah; (...); Girao, Henrique. "Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)". Autophagy (2021):
  14. Martins-Marques, Tania; Hausenloy, Derek J.; Sluijter, Joost P.G.; Leybaert, Luc; Girao, Henrique. "Intercellular Communication in the Heart: Therapeutic Opportunities for Cardiac Ischemia". Trends in Molecular Medicine (2020):
  15. Pereira, Patricia M. R.; Parada, Belmiro; Ribeiro-Rodrigues, Teresa M.; Fontes-Ribeiro, Carlos A.; Girão, Henrique; Tome, Joao P. C.; Fernandes, Rosa. "Caveolin-1 modulation increases efficacy of a galacto-conjugated phthalocyanine in bladder cancer cells resistant to photodynamic therapy". Molecular Pharmaceutics (2020): http://dx.doi.org/10.1021/acs.molpharmaceut.0c00298.
    10.1021/acs.molpharmaceut.0c00298
  16. Catarino, Steve; Ribeiro-Rodrigues, Teresa M; Sá Ferreira, Rita; Ramalho, José; Abert, Christine; Martens, Sascha; Girão, Henrique. "A Conserved LIR Motif in Connexins Mediates Ubiquitin-Independent Binding to LC3/GABARAP Proteins". Cells 9 4 (2020): 902.
  17. Martins-Marques, Tânia; Catarino, Steve; Gonçalves, Alexandre; Miranda-Silva, Daniela; Gonçalves, Lino M; Antunes, Pedro E; Coutinho, Gonçalo Freitas; et al. "EHD1 Modulates Cx43 Gap Junction Remodeling Associated with Cardiac Diseases". Circulation Research (2020):
  18. Hausenloy, Derek; Schulz R; Girao, Henrique; Kwak, Brenda R.; De Stefani D; Rosario Rizzuto R; Bernardi P; Di Lisa F. "Mitochondrial ion channels as targets for cardioprotection". Journal of Cellular and Molecular Medicine (accepted for publication) (2020):
  19. Hernandez-Resendiz S; Prunier F; Girao, Henrique; Dorn G; Hausenloy, Derek. "Targeting mitochondrial fusion and fission proteins for cardioprotection". J Cell Mol Med (accepted for publication) (2020):
  20. Batista-Almeida, Daniela; Ribeiro-Rodrigues, Teresa; Martins-Marques, Tânia; Cortes, Luisa; Antunes, Manuel J; Antunes, Pedro E; Gonçalves, Lino; et al. "Ischaemia impacts on TNT-mediated communication between cardiac cells". Current Research in Cell Biology (accepted for publication) (2020):
  21. Martins-Marques, Tania; Ribeiro-Rodrigues, Teresa; de Jager, Saskia C; Zuzarte, Monica; Ferreira, Cátia; Cruz, Pedro; Reis, Liliana; et al. "Myocardial infarction affects Cx43 content of extracellular vesicles secreted by cardiomyocytes". Life Science Alliance 3 12 (2020): e202000821.
  22. Santos-Ferreira, Cátia A.; Abreu, Mónica T.; Marques, Carla I.; Gonçalves, Lino M.; Baptista, Rui; Girão, Henrique M.. "Micro-RNA Analysis in Pulmonary Arterial Hypertension". JACC: Basic to Translational Science 5 11 (2020): 1149-1162.
  23. Tishchenko, Alexander; Azorín, Daniel D.; Vidal-Brime, Laia; Muñoz, María José; Arenas, Pol Jiménez; Pearce, Christopher; Girao, Henrique; Ramón y Cajal, Santiago; Aasen, Trond. "Cx43 and Associated Cell Signaling Pathways Regulate Tunneling Nanotubes in Breast Cancer Cells". Cancers 12 10 (2020): 2798.
  24. Gaspar, Laetitia S.; Santana, Magda M.; Henriques, Carina; Pinto, Maria M.; Ribeiro-Rodrigues, Teresa M.; Girão, Henrique; Nobre, Rui Jorge; Pereira de Almeida, Luís. "Simple and Fast SEC-Based Protocol to Isolate Human Plasma-Derived Extracellular Vesicles for Transcriptional Research". Molecular Therapy - Methods & Clinical Development 18 (2020): 723-737.
  25. Rusiecka, Olga M.; Montgomery, Jade; Morel, Sandrine; Batista-Almeida, Daniela; Van Campenhout, Raf; Vinken, Mathieu; Girao, Henrique; Kwak, Brenda R.. "Canonical and Non-Canonical Roles of Connexin43 in Cardioprotection". Biomolecules 10 9 (2020): 1225.
  26. Girão, Henrique. "A new predictive marker of ventricular remodeling associated with aortic stenosis". Revista Portuguesa de Cardiologia 39 7 (2020): 389-390.
  27. Aires, Inês Dinis; Ribeiro-Rodrigues, Teresa; Boia, Raquel; Catarino, Steve; Girão, Henrique; Ambrósio, António Francisco; Santiago, Ana Raquel. "Exosomes derived from microglia exposed to elevated pressure amplify the neuroinflammatory response in retinal cells". Glia 68 12 (2020): 2705-2724.
  28. Perrino, Cinzia; Ferdinandy, Péter; Bøtker, Hans E; Brundel, Bianca J J M; Collins, Peter; Davidson, Sean M; den Ruijter, Hester M; et al. "Improving translational research in sex-specific effects of comorbidities and risk factors in ischaemic heart disease and cardioprotection: position paper and recommendations of the ESC Working Group on Cellular Biology of the Heart". Cardiovascular Research 117 2 (2020): 367-385.
  29. Lissoni, Alessio; Hulpiau, Paco; Martins-Marques, Tânia; Wang, Nan; Bultynck, Geert; Schulz, Rainer; Witschas, Katja; et al. "RyR2 regulates Cx43 hemichannel intracellular Ca2+-dependent activation in cardiomyocytes". Cardiovascular Research (2019):
  30. Liberal, Joana; Costa, Gustavo; Carmo, Anália; Vitorino, Rui; Marques, Carla; Domingues, Maria Rosário; Domingues, Pedro; et al. "Chemical characterization and cytotoxic potential of an ellagitannin-enriched fraction from Fragaria vesca leaves". Arabian Journal of Chemistry 12 8 (2019): 3652-3666.
  31. Ferreira, Joao Vasco; Rosa Soares, Ana; Ramalho, José S.; Ribeiro-Rodrigues, Teresa; Máximo, Catarina; Zuzarte, Mónica; Girão, Henrique; Pereira, Paulo. "Exosomes and STUB1/CHIP cooperate to maintain intracellular proteostasis". PLOS ONE 14 10 (2019): e0223790.
  32. Martins-Marques, Tania; Ribeiro-Rodrigues, Teresa; Batista-Almeida, Daniela; Aasen, Trond; Kwak, Brenda R.; Girao, Henrique. "Biological Functions of Connexin43 Beyond Intercellular Communication". Trends in Cell Biology 29 10 (2019): 835-847.
  33. Dissmeyer, Nico; Coux, Olivier; Rodriguez, Manuel S.; Barrio, Rosa. "PROTEOSTASIS: A European Network to Break Barriers and Integrate Science on Protein Homeostasis". Trends in Biochemical Sciences 44 5 (2019): 383-387.
  34. Almeida Paiva, R.; Martins-Marques, T.; Jesus, K.; Ribeiro-Rodrigues, T.; Zuzarte, M.; Silva, A.; Reis, L.; et al. "Ischaemia alters the effects of cardiomyocyte-derived extracellular vesicles on macrophage activation". Journal of Cellular and Molecular Medicine 23 2 (2019): 1137-1151.
  35. Davidson, Sean M; Andreadou, Ioanna; Barile, Lucio; Birnbaum, Yochai; Cabrera-Fuentes, Hector A; Cohen, Michael V; Downey, James M; et al. "Circulating blood cells and extracellular vesicles in acute cardioprotection". Cardiovascular Research 115 7 (2018): 1156-1166.
  36. Bacalhau, Mafalda; Simões, Marta; Rocha, Mariana C.; Hardy, Steven A.; Vincent, Amy E.; Durães, João; Macário, Maria C.; et al. "Disclosing the functional changes of two genetic alterations in a patient with Chronic Progressive External Ophthalmoplegia: Report of the novel mtDNA m.7486G>A variant". Neuromuscular Disorders 28 4 (2018): 350-360.
  37. Anjo, Sandra I.; Martins-Marques, Tania; Pereira, Paulo; Girão, Henrique; Manadas, Bruno. "Elucidation of the dynamic nature of interactome networks: A practical tutorial". Journal of Proteomics 171 (2018): 116-126.
  38. Delgado-Silva, J.; Fernandes, R.; Pita, I.R.; Pereira, F.C.; Jaguszewski, M.; Gutiérrez-Chico, J.L.; Ribeiro-Rodrigues, T.; et al. "Intravascular imaging, histopathological analysis, and catecholamine quantification following catheter-based renal denervation in a swine model: the impact of prebifurcation energy delivery". Hypertension Research 41 9 (2018): 708-717.
  39. Pereira, Olga; Teixeira, Alexandra; Marques, Maria Belém Sousa Sampaio; Castro, Isabel; Girão, Henrique; Ludovico, Paula; Pereira, O.; et al. "Signalling mechanisms that regulate metabolic profile and autophagy of acute myeloid leukaemia cells". Journal of Cellular and Molecular Medicine 22 10 (2018): 4807-4817.
  40. Andreadou, Ioanna; (...); Girao, Henrique; Hausenloy, Derek. "Realizing the therapeutic potential of novel cardioprotective therapies: The EU-CARDIOPROTECTION COST Action - CA16225". Conditioning Medicine 1 3 (2018):
  41. Teresa M. Ribeiro-Rodrigues; Tânia Martins-Marques; Sandrine Morel; Brenda R. Kwak; Henrique Girão. "Role of connexin 43 in different forms of intercellular communication – gap junctions, extracellular vesicles and tunnelling nanotubes". Journal of Cell Science 130 21 (2017): 3619-3630.
  42. Baptista, Rui; Marques, Carla; Catarino, Steve; Enguita, Francisco J; Costa, Marina C; Matafome, Paulo; Zuzarte, Mónica; et al. "MicroRNA-424(322) as a new marker of disease progression in pulmonary arterial hypertension and its role in right ventricular hypertrophy by targeting SMURF1". Cardiovascular Research 114 1 (2017): 53-64.
  43. Balça-Silva, Joana; Matias, Diana; Dubois, Luiz Gustavo; Carneiro, Brenno; do Carmo, Anália; Girão, Henrique; Ferreira, Fernanda; et al. "The Expression of Connexins and SOX2 Reflects the Plasticity of Glioma Stem-Like Cells". Translational Oncology 10 4 (2017): 555-569.
  44. Ribeiro-Rodrigues, Teresa M.; Laundos, Tiago L.; Pereira-Carvalho, Rita; Batista-Almeida, Daniela; Pereira, Ricardo; Coelho-Santos, Vanessa; Silva, Ana P.; et al. "Exosomes secreted by cardiomyocytes subjected to ischaemia promote cardiac angiogenesis". Cardiovascular Research 113 11 (2017): 1338-1350.
  45. Ramalho, Ana Rita; Toscano, Adriana; Pereira, Paulo; Girão, Henrique; Gonçalves, Lino; Marques, Carla. "Hyperglycemia-induced degradation of HIF-1a contributes to impaired response of cardiomyocytes to hypoxia". Revista Portuguesa de Cardiologia 36 5 (2017): 367-373.
  46. Melo, Tânia; Domingues, Pedro; Ribeiro-Rodrigues, Teresa M.; Girão, Henrique; Segundo, Marcela A.; Domingues, M. Rosário M.. "Characterization of phospholipid nitroxidation by LC-MS in biomimetic models and in H9c2 Myoblast using a lipidomic approach". Free Radical Biology and Medicine 106 (2017): 219-227.
  47. Balça-Silva, Joana; Matias, Diana; Do Carmo, Anália; Dubois, Luiz Gustavo; Gonçalves, Ana Cristina; Girão, Henrique; Silva Canedo, Nathalie Henriques; et al. "Glioblastoma entities express subtle differences in molecular composition and response to treatment". Oncology Reports 38 3 (2017): 1341-1352.
  48. Deddens, Janine C.; Vrijsen, Krijn R.; Girao, Henrique; Doevendans, Pieter A.; Sluijter, Joost P. G.. "Cardiac-released extracellular vesicles can activate endothelial cells". Annals of Translational Medicine 5 3 (2017): 64-64.
  49. Catarino, S.; Pereira, P.; Girao, H.. "Molecular control of chaperone-mediated autophagy". Essays in Biochemistry 61 6 (2017): 663-674.
  50. M. Alves-Silva, Jorge; Zuzarte, Monica; Marques, Carla; Salgueiro, Ligia; Girao, Henrique. "Protective Effects of Terpenes on the Cardiovascular System: Current Advances and Future Perspectives". Current Medicinal Chemistry 23 40 (2016): 4559-4600.
  51. Pereira, Patrícia M.R.; Silva, Sandrina; Ramalho, José S.; Gomes, Célia M.; Girão, Henrique; Cavaleiro, José A.S.; Ribeiro, Carlos A.F.; Tomé, João P.C.; Fernandes, Rosa. "The role of galectin-1 in in vitro and in vivo photodynamic therapy with a galactodendritic porphyrin". European Journal of Cancer 68 (2016): 60-69.
  52. Pereira, Patrícia M. R.; Silva, Sandrina; Bispo, Mafalda; Zuzarte, Mónica; Gomes, Célia; Girão, Henrique; Cavaleiro, José A. S.; et al. "Mitochondria-Targeted Photodynamic Therapy with a Galactodendritic Chlorin to Enhance Cell Death in Resistant Bladder Cancer Cells". Bioconjugate Chemistry 27 11 (2016): 2762-2769.
  53. Da Silva-Ferrada, Elisa; Ribeiro-Rodrigues, Teresa M.; Rodríguez, Manuel S.; Girão, Henrique. "Proteostasis and SUMO in the heart". The International Journal of Biochemistry & Cell Biology 79 (2016): 443-450.
  54. Girao, Henrique. "Alteration in Phospholipidome Profile of Myoblast H9c2 Cell Line in a Model of Myocardium Starvation and Ischemia.". Journal of cellular physiology (2016):
  55. Girão, Henrique. "One small step for exosomes, one giant leap for Kawasaki disease". Revista Portuguesa de Cardiologia 35 5 (2016): 275-276.
  56. Gonçalves, Sara; Rodrigues, Inês Patrício; Padrão, Jorge; Silva, João Pedro; Sencadas, Vitor; Lanceros-Mendez, Senentxu; Girão, Henrique; et al. "Acetylated bacterial cellulose coated with urinary bladder matrix as a substrate for retinal pigment epithelium". Colloids and Surfaces B: Biointerfaces 139 (2016): 1-9.
  57. Martins-Marques, Tania; Pinho, Maria Joao; Zuzarte, Monica; Oliveira, Carla; Pereira, Paulo; Sluijter, Joost P. G.; Gomes, Celia; Girao, Henrique. "Presence of Cx43 in extracellular vesicles reduces the cardiotoxicity of the anti-tumour therapeutic approach with doxorubicin". Journal of Extracellular Vesicles 5 1 (2016): 32538.
  58. Iglesias, Bernardo A.; Barata, Joana F.B.; Pereira, Patrícia M.R.; Girão, Henrique; Fernandes, Rosa; Tomé, João P.C.; Neves, Maria G.P.M.S.; Cavaleiro, José A.S.. "New platinum(II)–bipyridyl corrole complexes: Synthesis, characterization and binding studies with DNA and HSA". Journal of Inorganic Biochemistry 153 (2015): 32-41.
  59. Tania Martins-Marques; Sandra Isabel Anjo; Paulo Pereira; Bruno Manadas; Henrique Girão. "Interacting Network of the Gap Junction (GJ) Protein Connexin43 (Cx43) is Modulated by Ischemia and Reperfusion in the Heart". Molecular & Cellular Proteomics 14 11 (2015): 3040-3055.
  60. Soares, Ana Rosa; Martins-Marques, Tania; Ribeiro-Rodrigues, Teresa; Ferreira, Joao Vasco; Catarino, Steve; Pinho, Maria João; Zuzarte, Monica; et al. "Gap junctional protein Cx43 is involved in the communication between extracellular vesicles and mammalian cells". Scientific Reports 5 1 (2015):
  61. Santos-Oliveira, Patrícia; Correia, António; Rodrigues, Tiago; Ribeiro-Rodrigues, Teresa M; Matafome, Paulo; Rodríguez-Manzaneque, Juan Carlos; Seiça, Raquel; Girão, Henrique; Travasso, Rui D. M.. "The Force at the Tip - Modelling Tension and Proliferation in Sprouting Angiogenesis". PLOS Computational Biology 11 8 (2015): e1004436.
  62. Martins-Marques, Tânia; Catarino, Steve; Marques, Carla; Pereira, Paulo; Girão, Henrique. "To beat or not to beat: degradation of Cx43 imposes the heart rhythm". Biochemical Society Transactions 43 3 (2015): 476-481.
  63. Ribeiro-Rodrigues, Teresa M.; Catarino, Steve; Pinho, Maria J.; Pereira, Paulo; Girao, Henrique. "Connexin 43 ubiquitination determines the fate of gap junctions: restrict to survive". Biochemical Society Transactions 43 3 (2015): 471-475.
  64. Vasco Ferreira, Joao; Rosa Soares, Ana; Silva Ramalho, Jose; Pereira, Paulo; Girao, Henrique. "K63 linked ubiquitin chain formation is a signal for HIF1A degradation by Chaperone-Mediated Autophagy". Scientific Reports 5 1 (2015):
  65. Martins-Marques, Tânia; Catarino, Steve; Marques, Carla; Matafome, Paulo; Ribeiro-Rodrigues, Teresa; Baptista, Rui; Pereira, Paulo; Girão, Henrique. "Heart ischemia results in connexin43 ubiquitination localized at the intercalated discs". Biochimie 112 (2015): 196-201.
  66. Martins-Marques, Tania; Catarino, Steve; Zuzarte, Monica; Marques, Carla; Matafome, Paulo; Pereira, Paulo; Girão, Henrique. "Ischaemia-induced autophagy leads to degradation of gap junction protein connexin43 in cardiomyocytes". Biochemical Journal 467 2 (2015): 231-245.
  67. Balça-Silva, Joana; Matias, Diana; do Carmo, Anália; Girão, Henrique; Moura-Neto, Vivaldo; Sarmento-Ribeiro, Ana Bela; Lopes, Maria Celeste. "Tamoxifen in combination with temozolomide induce a synergistic inhibition of PKC-pan in GBM cell lines". Biochimica et Biophysica Acta (BBA) - General Subjects 1850 4 (2015): 722-732.
  68. Martins-Marques, Tania; Ribeiro-Rodrigues, Teresa; Pereira, Paulo; Codogno, Patrice; Girao, Henrique. "Autophagy and Ubiquitination in Cardiovascular Diseases". DNA and Cell Biology 34 4 (2015): 243-251.
  69. Gonçalves, Sara; Padrão, Jorge; Rodrigues, Inês Patrício; Silva, João Pedro; Sencadas, Vítor; Lanceros-Mendez, Senentxu; Girão, Henrique; Dourado, Fernando; Rodrigues, Lígia R.. "Bacterial Cellulose As a Support for the Growth of Retinal Pigment Epithelium". Biomacromolecules 16 4 (2015): 1341-1351.
  70. Santos-Almeida, Fernanda Machado; Girão, Henrique; da Silva, Carlos Alberto Aguiar; Salgado, Helio Cesar; Fazan, Rubens. "Cholinergic stimulation with pyridostigmine protects myocardial infarcted rats against ischemic-induced arrhythmias and preserves connexin43 protein". American Journal of Physiology-Heart and Circulatory Physiology 308 2 (2015): H101-H107.
  71. Lourenço, Leandro M. O.; Iglesias, Bernardo A.; Pereira, Patrícia M. R.; Girão, Henrique; Fernandes, Rosa; Neves, Maria G. P. M. S.; Cavaleiro, José A. S.; Tomé, João P. C.. "Synthesis, characterization and biomolecule-binding properties of novel tetra-platinum(ii)-thiopyridylporphyrins". Dalton Transactions 44 2 (2015): 530-538.
  72. Liberal, Joana; Francisco, Vera; Costa, Gustavo; Figueirinha, Artur; Amaral, Maria Teresa; Marques, Carla; Girão, Henrique; et al. "Bioactivity of Fragaria vesca leaves through inflammation, proteasome and autophagy modulation". Journal of Ethnopharmacology 158 (2014): 113-122.
  73. Liberal, J; Costa, G; Marques, C; Girão, H; Vitorino, R; Domingues, R; Domingues, P; Cruz, MT; Batista, MT. "iTRAQ-based proteomic analysis of ellagitannins-enriched fraction from Fragaria vesca leaves on HepG2 cells". Planta Medica 80 16 (2014): 1438-1438.
  74. Ribeiro-Rodrigues, Teresa M.; Catarino, Steve; Marques, Carla; Ferreira, João V.; Martins-Marques, Tânia; Pereira, Paulo; Girão, Henrique. "AMSH-mediated deubiquitination of Cx43 regulates internalization and degradation of gap junctions". The FASEB Journal 28 11 (2014): 4629-4641.
  75. Simões-Correia, Joana; Silva, Diana I.; Melo, Soraia; Figueiredo, Joana; Caldeira, Joana; Pinto, Marta T.; Girão, Henrique; Pereira, Paulo; Seruca, Raquel. "DNAJB4 molecular chaperone distinguishes WT from mutant E-cadherin, determining their fate in vitro and in vivo". Human Molecular Genetics 23 8 (2013): 2094-2105.
  76. Ferreira, J.V.; Fofo, H.; Bejarano, E.; Bento, C.F.; Ramalho, J.S.; Girao, H.; Pereira, P.. "STUB1/CHIP is required for HIF1A degradation by chaperone-mediated autophagy". Autophagy 9 9 (2013): 1349-1366.
  77. Bejarano, E.; Girao, H.; Yuste, A.; Patel, B.; Marques, C.; Spray, D.C.; Pereira, P.; Cuervo, A.M.. "Autophagy modulates dynamics of connexins at the plasma membrane in a ubiquitin-dependent manner". Molecular Biology of the Cell 23 11 (2012): 2156-2169.
  78. Catarino, S.; Ramalho, J.S.; Marques, C.; Pereira, P.; Girão, H.. "Ubiquitin-mediated internalization of connexin43 is independent of the canonical endocytic tyrosine-sorting signal". Biochemical Journal 437 2 (2011): 255-267.
  79. Girão, H.; Catarino, S.; Pereira, P.. "Eps15 interacts with ubiquitinated Cx43 and mediates its internalization". Experimental Cell Research 315 20 (2009): 3587-3597.
  80. Girao, H.; Geli, M.-I.; Idrissi, F.-Z.. "Actin in the endocytic pathway: From yeast to mammals". FEBS Letters 582 14 (2008): 2112-2119.
  81. Girão, Henrique; Pereira, Paulo; Girao, H.; Pereira, P.. "The proteasome regulates the interaction between Cx43 and ZO-1". Journal of Cellular Biochemistry 102 3 (2007): 719-728.
  82. Girão, Henrique; Pereira, Paulo; Taylor, Allen; Shang, Fu; Girão, H.; Pereira, P.; Taylor, A.; Shang, F.. "Subcellular redistribution of components of the ubiquitin-proteasome pathway during lens differentiation and maturation". Investigative Ophthalmology and Visual Science 46 4 (2005): 1386-1392.
  83. Girão, Henrique; Catarino, Steve; Pereira, Paulo. "7-Ketocholesterol Modulates Intercellular Communication Through Gap-Junction in Bovine Lens Epithelial Cells". Cell Communication and Signaling 2 1 (2004): 2.
  84. Fernandes, Rosa; Girão, Henrique; Pereira, Paulo; Fernandes, R.; Girão, H.; Pereira, P.. "High glucose down-regulates intercellular communication in retinal endothelial cells by enhancing degradation of connexin 43 by a proteasome-dependent mechanism". Journal of Biological Chemistry 279 26 (2004): 27219-27224.
  85. Pereira, P.; Shang, F.; Hobbs, M.; Girão, H.; Taylor, A.; Pereira, Paulo; Shang, Fu; et al. "Lens fibers have a fully functional ubiquitin-proteasome pathway". Experimental Eye Research 76 5 (2003): 623-631.
  86. Girão, H.; Shang, F.; Pereira, P.. "7-Ketocholesterol stimulates differentiation of lens epithelial cells". Molecular Vision 9 (2003): 497-501.
  87. Girão, H.; Pereira, P.; Ramalho, J.; Quinlan, R.; Prescott, A.. "Cholesterol oxides mediated changes in cytoskeletal organisation involves Rho GTPases". Experimental Cell Research 291 2 (2003): 502-513.
  88. Henrique Girao; Paulo Pereira. "Phosphorylation of connexin 43 acts as a stimuli for proteasome-dependent degradation of the protein in lens epithelial cells". Molecular Vision 9 (2003): 24-30.
  89. Girao, Henrique; Paulo, P.. "Effect of cholesterol oxides in ubiquitin conjugation in the lens". Investigative Ophthalmology & Visual Science (2001):
  90. Paulo Pereira; Girao, Henrique. "Degradation of connexin 43 by ubiquitin-proteasome pathway in the lens". Investigative Opthalmology & Visual Science 42 suppl S (2001):
  91. Girao, H.; Mota, C.; Pereira, P.. "Cholesterol may act as an antioxidant in lens membranes". Current Eye Research 18 6 (1999): 448-454.
  92. Girão, H.; Mota, M.C.; Ramalho, J.; Pereira, P.. "Cholesterol oxides accumulate in human cataracts". Experimental Eye Research 66 5 (1998): 645-652.
  93. Girao, Henrique; Pereira, P.; Ramalho, JS; Mota, MC. "Cholesterol may cooperate with vitamin E in the antioxidant protection of human lenses". Investigative Ophthalmology & Visual Science (1997):
  94. Girao, Henrique; Paulo Pereira; JS Ramalho; MC Mota. "Cholesterol oxidation in lens membranes: Implications on cataract development". Investigative Ophthalmology & Visual Science (1996):
  95. Girao, H; Pereira, P.; Ramalho, JS; Mota, MC. "Cholesterol may modulate membrane susceptibility to oxidation in cataractous lens". Vision Research 35 1 (1995): S141.
Capítulo de livro
  1. Batista-Almeida, Daniela; Martins-Marques, Tania; Ribeiro-Rodrigues, Teresa; Girao, Henrique. "The Role of Proteostasis in the Regulation of Cardiac Intercellular Communication". In Advances in Experimental Medicine and Biology, 279-302. Springer International Publishing, 2020.
  2. M. Alves-Silva, Jorge; Barbeitos Júlia; Carla Marques; Ligia Salgueiro; Girao, Henrique; Monica Zuzarte. "Effects on the Cardiovascular System of Terpene-Rich Essential Oils". In Terpenes : biosynthesis, applications and research. 2018.
  3. Martins-Marques, Tania; Anjo, Sandra I.; Ribeiro-Rodrigues, Teresa; Manadas, Bruno; Girao, Henrique. "Targeted Approach for Proteomic Analysis of a Hidden Membrane Protein". In Methods in Molecular Biology, 151-172. Springer New York, 2017.
  4. Ferreira, J.V.; Pereira, P.; Girao, H.. "Role of Chaperone-Mediated Autophagy in Ageing and Neurodegeneration". In Toxicity and Autophagy in Neurodegenerative Disorders, 25-40. Springer International Publishing, 2015.
Poster em conferência
  1. Steve Catarino; Teresa M. Ribeiro-Rodrigues; Lino Gonçalves; Tania Martins-Marques; Girao, Henrique. "Cardiac ischemia modulates the sorting of Cx43 into EVs". Trabalho apresentado em International Gap Junction Conference 2019 (Victoria BC, Canada), 2019.
  2. Girao, Henrique. "Cx43 hemichannel intracellular Ca2+/RyR2-dependent activation in cardiomyocytes". Trabalho apresentado em International gap Junction Conference 2019 (Victoria BC, Canada), 2019.
  3. Girao, Henrique. "EHD1 promotes lateralization of the gap junction protein Cx43 in the ischemic heart". Trabalho apresentado em International Gap Junction Conference 2019 (Victoria BC, Canada), 2019.
  4. Girao, Henrique. "Direct interaction with LC3 modulates Cx43 degradation in endothelial cells". Trabalho apresentado em International Gap Junction Conference 2019 (Victoria BC, Canada), 2019.
  5. Girao, Henrique. "EHD proteins mediate gap junction (GJ) remodeling during myocardial ischemia". Trabalho apresentado em 4th COST Action EU-CARDIOPROTECTION Meeting 2019 (Kragujevac, Serbia), 2019.
  6. Girao, Henrique. "Ischemia impacts on TNT-medited communication between cardiomyocytes". Trabalho apresentado em Meeting on Vesicular Biology (MVB) (Coimbra, Portugal), 2018.
  7. Chetty, C.; Braun, R.K.; Schmitt, T.E.; Pellmann, E.M.; Balasubramaniam, V.. "Ischemia alters the effects of cardiomyocyte-derived extracellular vesicles on macrophage activation". Trabalho apresentado em IX Meeting on Signal Transduction - SINAL 2018 (Lisbon, Portugal), 2018.
  8. Girao, Henrique. "Cx43 interacts directly with LC3 protein family members through a LIR motif". Trabalho apresentado em 1st Meeting on Vesicular Biology (Coimbra, Portugal), 2018.
  9. Girao, Henrique. "EHD proteins mediate gap junction (GJ) remodeling during myocardial ischemia". Trabalho apresentado em ESC Congress (Munich, Germany), 2018.
  10. Girao, Henrique. "EHD1 modulates intercellular trafficking of the gap junction Cx43". Trabalho apresentado em 1st Meeting on Vesicular Biology (Coimbra, Portugal), 2018.
  11. Girao, Henrique. "A new regulatory mechanism of Cx43 degradation in the heart: CMA enters the stage". Trabalho apresentado em SINAL - 8th Meeting on Signal Transduction (Lisbon, Portugal), 2017.
  12. Girao, Henrique. "A new regulatory mechanism for Cx43 degradation in the heart: CMA enters the stage". Trabalho apresentado em International Gap Junction Conference Meeting (IGJC) (Glasgow, UK), 2017.
  13. Girao, Henrique. "Interaction between Cx43 and LC3: an ubiuitin-indepedent pathway for degradation of Cx43 by autophagy". Trabalho apresentado em SINAL 2017 - 8th Meeting on Signal Transduction (Lisbon, Portugal), 2017.
  14. Girao, Henrique. "EHD1 regulates the internalization of Cx43 - a new player of ischemia-induced remodeling of gap junction in the heart?". Trabalho apresentado em International Gap Junction Conference (IGJC) (Glasgow, UK), 2017.
  15. Girao, Henrique. "EHD1 regulates the internalization of Cx43 - a new player of ischemia-induced remodeling of gap junction in the heart?". Trabalho apresentado em SINAL - 8th Meeting on Signal Transduction (Lisbon, Portugal), 2017.
  16. Girao, Henrique. "EHD1 regulates the internalization of Cx43 - a new player of ischemia-induced remodeling of gap junction in the heart?". Trabalho apresentado em 7th UK Gap Junction Meeting (Warwick, UK), 2016.
  17. Girao, Henrique. "A new regulatory mechanism of Cx43 degradation in the heart: CMA enters the stage". Trabalho apresentado em 3rd PROTEOSTASIS Action Meeting (Lisbon, Portugal), 2016.
  18. Girao, Henrique. "EHD1 regulates the internalization of Cx43 - a new player of ischemia-induced remodeling of gap junction in the heart?". Trabalho apresentado em 3rd PROTEOSTASIS Action Meeting (Lisbon, Portugal), 2016.
  19. Girao, Henrique. "Interaction between Cx43 and LC3: an ubiquitin-independent pathway for degradation of Cx43 by autophagy". Trabalho apresentado em 3rd PROTEOSTASIS Action Meeting (Lisbon, Portugal), 2016.
  20. Girao, Henrique. "To beat or not to beat: detrimental autophagy contributes to gap junctions degradation in ischemic heart". Trabalho apresentado em Molecular Biology of Ageing Meeting (Groningen, The Netherlands), 2015.
  21. Girao, Henrique. "Cx43 mediates the interaction of exosomes with the target cells". Trabalho apresentado em 1st Iberian Meeting on Extracellular Vesicles (Porto, Portugal), 2015.
  22. Girao, Henrique. "The protective effect of starvation in the heart involves an improvement of gap junction intercellular communication". Trabalho apresentado em Heart with/out Borders - Cardiovascular Development, Disease and repair - International Conference (Porto, Portugal), 2014.
  23. Girao, Henrique. "To beat or not to beat: detrimental autophagy contributes to gap junctions degradation in ischemic heart". Trabalho apresentado em XXXV Congresso da Sociedade Portuguesa de Cardiologia (Algarve, Portugal), 2014.
  24. Girao, Henrique. "AMSH-mediated deubiquitination of Cx43 regulates internalization and degradation of gap junctions". Trabalho apresentado em 7th UK Gap Junction Meeting (Glasgow, UK), 2014.
  25. Girao, Henrique. "Connexin 43: a new substrate for chaperone-mediated autophagy". Trabalho apresentado em Heart with/out Borders - Cardiovascular Development, Disease and Repair (Porto, Portugal), 2014.
  26. Girao, Henrique. "AMSH-mediated deubiquitination of Cx43 regulates internalization and degradation of gap junctions". Trabalho apresentado em EMBO Pratical Course - Ubiquitin unrelated modifiers (Alghero, Italy), 2014.
  27. Rasmussen, NL; Totland, MZ; Basing, S; Knudsen, LM; Yohannes, Z; Lothe, R; Leithe, E. "Ubiquitin targets Connexin43 localized at the intercalated discs in ischemic heart". Trabalho apresentado em Heart with/out Borders (Porto, Portugal), 2014.
  28. Girao, Henrique. "To beat or not to beat: detrimental autophagy contributes to gap junctions degradation in ischemic heart". Trabalho apresentado em 7th UK Gap Junctions Meeting (Glasgow, UK), 2014.
  29. Girao, Henrique. "To beat or not to beat: detrimental autophagy contributes to gap junctions degradation in ischemic heart". Trabalho apresentado em ESC Congress 2013 (Amesterdam, The Netherlands), 2013.
  30. Girao, Henrique. "To beat or not to beat: detrimental autophagy contributes to gap junctions degradation in ischemic heart". Trabalho apresentado em 7th National Meeting on Cell Signaling - SINAL (Aveiro, Portugal), 2013.
  31. Girao, Henrique. "Presentation of >40 posters in International and National Scientific Meetings (2013-2022)". 2013.
Tese / Dissertação
  1. Girao, Henrique. "Alvos em movimento: contribuição para o estudo da degradação proteica em sistemas visuais". Doutoramento, Universidade de Coimbra Faculdade de Medicina, 2006.
  2. Girao, Henrique. "Implicações da oxidação do colesterol no desenvolvimento da catarata". Mestrado, Universidade de Coimbra Faculdade de Medicina, 1998.
Distinções

Prémio

2021 Best Paper in Cardiovascular Sciences - AIDFM-CETERA 2020 (1st Place)
2019 FMUC Best Researcher
Universidade de Coimbra Faculdade de Medicina, Portugal