???global.info.a_carregar???
Paulo Aguiar graduated in Physics ("Engª Física Tecnológica") from Instituto Superior Técnico, University of Lisbon, Portugal, and completed the course work in the Biophysics Doctoral Program at the Institute for Biophysics and Biomedical Engineering, University of Lisbon in 2001 (final grade 95/100, among the highest achieved in the program). He then moved to the United Kingdom to continue his studies at the Institute for Adaptive and Neural Computation, University of Edinburgh. After finishing his PhD in Computational Neuroscience (U. Edinburgh, 2006) he joined, as a postdoc in neurobiology, the Neuroscience Unit at the Institute for Molecular and Cellular Biology, Portugal. In 2008 he was awarded a competitive researcher grant in Computational Biology, and in 2013 he was invited to join the National Institute for Biomedical Engineering (INEB) as an Assistant Investigator. Since 2016 he is a Principal Investigator at the Institute for Research and Innovation in Health (i3S), the largest R&D institution for health sciences research in Portugal, where he leads the Neuroengineering and Computational Neuroscience Lab (NCN). Sign of his scientific recognition, he was elected in 2019 Vice-Coordinator of the Neurobiology and Neurologic Disorders Research Program at i3S (harboring 23 research groups). He is also invited Associate Prof. at ICBAS, invited Associate Prof. in Neuroengineering at Faculty of Engineering, and Affiliate Prof. in Biophysics at Faculty of Medicine, all at Univ. of Porto. He has been responsible for several courses in physics, mathematics, neurobiology and engineering, and has received a Univ. of Porto Pedagogical Score of 6.7/7.0 by the students. He has supervised and co-supervised 16 PhD students (completed + ongoing). Paulo Aguiar is author in 70+ international peer-reviewed publications (including in Science, Nature Cell Biology, Nature Methods, J. Neuroscience, eLife, PNAS, J. Neural Eng., Medical Image Analysis; over 4200 citations). He has been already (co)PI/Task Leader in 18 national and international research projects, obtained in competitive calls.
Ler resumo completo ↓
Identificação

Identificação pessoal

Nome completo
Paulo de Castro Aguiar

Nomes de citação

  • Aguiar, Paulo

Identificadores de autor

Ciência ID
0413-0808-A59C
ORCID iD
0000-0003-4164-5713
Google Scholar ID
Jwr9SgMAAAAJ
Scopus Author Id
36842157600

Endereços de correio eletrónico

  • pauloaguiar@i3s.up.pt (Profissional)

Telefones

Telefone
  • 220408800 (Profissional)

Moradas

  • Rua Alfredo Allen, 208, 4200-135, Porto, Porto, Portugal (Profissional)

Websites

Domínios de atuação

  • Ciências da Engenharia e Tecnologias - Engenharia Médica
  • Ciências Médicas e da Saúde - Medicina Básica - Neurociências
  • Ciências Exatas - Ciências da Computação e da Informação - Bioinformática
  • Ciências Naturais - Ciências Biológicas - Biofísica
  • Ciências Exatas - Ciências da Computação e da Informação - Ciências da Informação
  • Ciências Exatas - Ciências da Computação e da Informação - Ciências da Computação

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2)
Francês Utilizador elementar (A1) Utilizador independente (B1) Utilizador independente (B1) Utilizador elementar (A1)
Japonês Utilizador elementar (A1) Utilizador elementar (A1)
Formação
Grau Classificação
2006/06/21
Concluído
 PhD (Doctor of Philosophy)
The University of Edinburgh Institute for Adaptive and Neural Computation, Reino Unido
"A General Hippocampal Computational Model: Episodic and Spatial Memory Combined in a Spiking Model" (TESE/DISSERTAÇÃO)
2003/08/01 - 2003/08/31
Concluído
 Advanced Course in Computational Neuroscience (Outros)
IBRO - International Brain Research Organization, França
2001/07/31
Concluído
 Doctoral Training Program in Biophysics and Biomedical Engineering (Curso de doutoramento (conclusão de unidades curriculares))
Universidade de Lisboa Instituto de Biofísica e Engenharia Biomédica, Portugal
 19/20
1995/09/01 - 2000/07/31
Concluído
 Engenharia Física Tecnológica (Mestrado integrado)
Instituto Superior Técnico Departamento de Física, Portugal
 16/20
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2022/01/01 - Atual Investigador principal (carreira) (Investigação) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2016/11/01 - Atual Investigador principal (carreira) (Investigação) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2013/05/02 - 2016/10/31 Investigador Auxiliar (carreira) (Investigação) Instituto Nacional de Engenharia Biomédica, Portugal
2015/02/01 - 2015/02/15 Investigador visitante (Investigação) Universiteit Antwerpen Campus Drie Eiken, Bélgica
2008/05/02 - 2013/05/01 Investigador Auxiliar (carreira) (Investigação) Universidade do Porto Faculdade de Ciências, Portugal
2006/06/22 - 2008/05/01 Pós-doutorado (Investigação) Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento 		Empregador
2017 - Atual Professor Associado Convidado (Docente Universitário) Universidade do Porto Faculdade de Engenharia, Portugal
2021/01 - 2022 Professor Associado Convidado (Docente Universitário) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Cargos e Funções

Categoria Profissional
Instituição de acolhimento 		Empregador
2019/12 - Atual Vice-Coordinator of the i3S Integrative Program on Neurobiology and Neurologic Disorders. Member of the i3S Restricted Scientific Committee Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2017 - 2019 Scientific Coordinator of the Bioimage Analysis Platform at INEB Instituto Nacional de Engenharia Biomédica, Portugal

Outros

Categoria Profissional
Instituição de acolhimento 		Empregador
2014 - Atual Affiliate Professor (Biophysics) Universidade do Porto Faculdade de Medicina, Portugal
Projetos

Bolsa

Designação Financiadores
2023/01/01 - 2025/12/31 smartDBS - Improving Deep Brain Stimulation in Parkinson’s Disease with Personalized Electrophysiological Biomarkers and Data-Driven Stimulation
Prémio Mantero Belard, MB-12-22
Investigador responsável
Santa Casa da Misericórdia de Lisboa
2022/12/31 - 2025/12/30 NeuroSpark - Neuromorphic devices for adaptive real-time neuromodulation in brain electrical stimulation therapies
HR22-00189
Investigador responsável
Obra Social La Caixa
2022/01/01 - 2024/12/31 Storing and recalling biological Memories with Neuromorphic Electronics
PTDC/NAN-MAT/4093/2021
Investigador
Fundação para a Ciência e a Tecnologia
2021 - 2024 Spatiotemporal dissection of nuclear mechanics in the maintenance of chromosomal stability
PTDC/BIA-CEL/6740/2020
Investigador
Fundação para a Ciência e a Tecnologia
Em curso
2022/01/01 - 2023/06/30 Dissecting the mechanisms underlying tension-driven axon growth.
EXPL/BIA-CEL/0717/2021
Investigador
Fundação para a Ciência e a Tecnologia
2019 - 2022 Mind The Gap: decoding and bridging somatosensory information in the spinal cord
PTDC/EMD-EMD/31540/2017
Investigador responsável
Fundação para a Ciência e a Tecnologia
Em curso
2018 - 2021 NIMAS - New Active Medical Implants
PTDC/EEI-EEE/32348/2017
Investigador
Fundação para a Ciência e a Tecnologia
Em curso
2018 - 2021 ACTinRING - Uncovering the mechanistic assembly and function of actin ring networks in axonal biology and pathology
02/SAICT/2017/28623
Investigador
Fundação para a Ciência e a Tecnologia
Em curso
2016 - 2019 Combinatorial regenerative strategy to potentiate axon regeneration and improve functional recovery after spinal cord injury
Prémio Melo e Castro
Investigador
Santa Casa da Misericórdia de Lisboa
Concluído
2017 - 2018 Facegram - a new standard and a universal tool for detailed analysis of facial movements in the context of therapy, surgery and rehabilitation of the face
FACEGRAM
Investigador responsável
Comissao de Coordenacao e Desenvolvimento Regional do Norte
Concluído
2017 - 2018 mCBEEs - Advanced integrative solutions to Corrosion problems beyond micro–scale: towards long-term durability of miniaturized Biomedical, Electronic and Energy systems
Marie Sklodowska-Curie grant agreement No 764977
Investigador
European Commission Marie Sklodowska-Curie Actions
2016 - 2018 Spatiotemporal control of mitotic spindle assembly
PTDC/BEX-BCM/1758/2014
Investigador
Fundação para a Ciência e a Tecnologia
2016 - 2018 Biodegradable dendrimers for targeted neuroprotective therapies in stroke
PTDC/CTM-NAN/3547/2014
Investigador
Fundação para a Ciência e a Tecnologia
2016 - 2018 Sensory innervation in the complex orchestration of bone regeneration: interplay in microfluidics platforms
PTDC/BIM-MED/4041/2014
Investigador
Fundação para a Ciência e a Tecnologia
Concluído
2016 - 2018 Hybrid neuron-memristor adaptive platform (NeuronMAP)
PTDC/CTM-NAN/3146/2014
Investigador
Fundação para a Ciência e a Tecnologia
Concluído
2016 - 2018 NEUBIAS: Network of European BioImage Analysts
COST Action CA15124
Investigador
European Cooperation in Science and Technology
Concluído
2014 - 2018 Memristors - Devices, Models, Circuits, Systems and Applications (MemoCiS)
COST Action IC1401
Investigador
European Cooperation in Science and Technology
Concluído
2013/04 - 2015/04 Y1 receptor based therapy for local bone repair: Antagonist behavior and delivery in challenged bone microenvironment
Provided by PTCRIS: 125869
125869
PTDC/BIM-MED/1047/2012
Investigador
Ministério da Ciência Tecnologia e Ensino Superior
Concluído
2012/04 - 2015/03 Memristor Based Adaptive Neural Networks (MemBrAiNN)
Provided by PTCRIS: 122868
122868
PTDC/CTM-NAN/122868/2010
Investigador
Fundação para a Ciência e a Tecnologia
Concluído
2007/07 - 2010/06 Theoretical models of nociceptive information processing and transmission in the spinal cord´s dorsal horn.
68929
Provided by PTCRIS: 68929
PTDC/SAU-NEU/68929/2006
Investigador responsável
Ministério da Ciência Tecnologia e Ensino Superior
2000/09/01 - 2001/07/31 Study of Type Ia supernovae and their cosmological implications
PESO/ESO/P/PRO/1257/98
Bolseiro de Doutoramento
Instituto Superior Técnico Departamento de Física, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído

Projeto

Designação Financiadores
2018/07/01 - 2022/06/30 Uncovering the mechanistic assembly and function of actin ring networks in axonal biology and pathology.
PTDC/MED-NEU/28623/2017
International Iberian Nanotechnology Laboratory, Portugal

Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Instituto Nacional de Engenharia Biomédica, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2019/05/01 - 2021/12/18 New Active Medical Implants
PTDC/EEI-EEE/32348/2017
International Iberian Nanotechnology Laboratory, Portugal

Universidade do Porto, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2018/07/01 - 2021/06/30 Pathological nerve sprouting in bone metastases: OSTEOCLASTS, what are you doing
PTDC/MED-PAT/30158/2017
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal

Instituto Nacional de Engenharia Biomédica, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
Produções

Publicações

Artigo em conferência
  1. Monteiro, J.P.; Oliveira, H.P.; Aguiar, P.; Cardoso, J.S.. "A depth-map approach for automatic mice behavior recognition". 2014.
    10.1109/ICIP.2014.7025458
  2. Aguiar, P.; David, A.; Paulo, S.; Rosa, A.. "EEGSolver - Brain activity and genetic algorithms". 2000.
    10.1145/335603.335702
Artigo em revista
  1. J. C. Mateus; M. M. Sousa; J. Burrone; P. Aguiar; MATEUS, JOSÉ C; Sousa, Monica M; Burrone, Juan; et al. Autor correspondente: Aguiar, Paulo. "Beyond a Transmission Cable—New Technologies to Reveal the Richness in Axonal Electrophysiology". The Journal of Neuroscience (2024): https://doi.org/10.1523/JNEUROSCI.1446-23.2023.
    No prelo • 10.1523/JNEUROSCI.1446-23.2023
  2. Domingos L Castro; Miguel Aroso; A Pedro Aguiar; David B Grayden; Paulo Aguiar. "Disrupting abnormal neuronal oscillations with adaptive delayed feedback control". eLife (2024): https://doi.org/10.7554/eLife.89151.
    10.7554/eLife.89151
  3. Andreia M. Oliveira; Luis Coelho; Eduardo Carvalho; Manuel J. Ferreira-Pinto; Rui Vaz; Paulo Aguiar. "Machine learning for adaptive deep brain stimulation in Parkinson’s disease: closing the loop". Journal of Neurology (2023): https://doi.org/10.1007/s00415-023-11873-1.
    10.1007/s00415-023-11873-1
  4. Francisca Diniz; Sofia Lamas; Hugo Osório; Paulo Aguiar; Daniela Freitas; Fátima Gärtner; Bruno Sarmento; Celso A. Reis; Joana Gomes. "Nanoparticles targeting Sialyl-Tn for efficient tyrosine kinase inhibitor delivery in gastric cancer". Acta Biomaterialia (2023): https://doi.org/10.1016/j.actbio.2023.08.014.
    10.1016/j.actbio.2023.08.014
  5. Manubens-Gil, L.; Zhou, Z.; Chen, H.; Ramanathan, A.; Liu, X.; Liu, Y.; Bria, A.; et al. "BigNeuron: a resource to benchmark and predict performance of algorithms for automated tracing of neurons in light microscopy datasets". Nature Methods 20 6 (2023): 824-835. http://www.scopus.com/inward/record.url?eid=2-s2.0-85153062588&partnerID=MN8TOARS.
    10.1038/s41592-023-01848-5
  6. Margarida Dantas; Andreia Oliveira; Paulo Aguiar; Helder Maiato; Jorge G. Ferreira. "Nuclear tension controls mitotic entry by regulating cyclin B1 nuclear translocation". Journal of Cell Biology (2022): https://doi.org/10.1083/jcb.202205051.
    10.1083/jcb.202205051
  7. Eduardo Conde-Sousa; João Vale; Ming Feng; KELE XU; Yin Wang; Della Mea V; David La Barbera; et al. "HEROHE Challenge: Predicting HER2 Status in Breast Cancer from Hematoxylin–Eosin Whole-Slide Imaging". Journal of Imaging (2022): https://www.mdpi.com/2313-433X/8/8/213.
    10.3390/jimaging8080213
  8. Ana C. Almeida; Joana Soares-de-Oliveira; Danica Drpic; Liam P. Cheeseman; Joana Damas; Harris A. Lewin; Denis M. Larkin; et al. "Augmin-dependent microtubule self-organization drives kinetochore fiber maturation in mammals". Cell Reports (2022): https://doi.org/10.1016/j.celrep.2022.110610.
    10.1016/j.celrep.2022.110610
  9. Urša Blenkuš; Ana Filipa Gerós; Cristiana Carpinteiro; Paulo de Castro Aguiar; I. Anna S. Olsson; Nuno Henrique Franco. "Non-Invasive Assessment of Mild Stress-Induced Hyperthermia by Infrared Thermography in Laboratory Mice". Animals (2022): https://doi.org/10.3390/ani12020177.
    10.3390/ani12020177
  10. Mateus, J.C.; Weaver, S.; Van Swaay, D.; Renz, A.F.; Hengsteler, J.; Aguiar, P.; Vörös, J.. "Nanoscale Patterning of in Vitro Neuronal Circuits". ACS Nano 16 4 (2022): 5731-5742. http://www.scopus.com/inward/record.url?eid=2-s2.0-85129103498&partnerID=MN8TOARS.
    10.1021/acsnano.1c10750
  11. Dias, C.; Castro, D.; Aroso, M.; Ventura, J.; Aguiar, P.. "Memristor-Based Neuromodulation Device for Real-Time Monitoring and Adaptive Control of Neuronal Populations". ACS Applied Electronic Materials (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85130149541&partnerID=MN8TOARS.
    10.1021/acsaelm.2c00198
  12. Neto, E.; Leitão, L.; Mateus, J.C.; Sousa, D.M.; Alves, C.J.; Aroso, M.; Monteiro, A.C.; et al. "Osteoclast-derived extracellular vesicles are implicated in sensory neurons sprouting through the activation of epidermal growth factor signaling". Cell and Bioscience 12 1 (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85135937935&partnerID=MN8TOARS.
    10.1186/s13578-022-00864-w
  13. Mateus, JC; Lopes, CDF; Aroso, M; Costa, AR; Gerós, A; Meneses, J; Faria, P; et al. "Bidirectional flow of action potentials in axons drives activity dynamics in neuronal cultures". Journal of Neural Engineering 18 6 (2021): 066045. http://dx.doi.org/10.1088/1741-2552/ac41db.
    10.1088/1741-2552/ac41db
  14. Teixeira, H.; Dias, C.; Aguiar, P.; Ventura, J.. "Gold-Mushroom Microelectrode Arrays and the Quest for Intracellular-Like Recordings: Perspectives and Outlooks". Advanced Materials Technologies 6 2 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85097519751&partnerID=MN8TOARS.
    10.1002/admt.202000770
  15. Polónia, António; Campelos, Sofia; Ribeiro, Ana; Aymore, Ierece; Pinto, Daniel; Biskup-Fruzynska, Magdalena; Veiga, Ricardo Santana; et al. "Artificial Intelligence Improves the Accuracy in Histologic Classification of Breast Lesions". American Journal of Clinical Pathology 155 4 (2020): 527-536. http://dx.doi.org/10.1093/ajcp/aqaa151.
    10.1093/ajcp/aqaa151
  16. Ana Gerós; Ana Magalhães; Paulo Aguiar. "Improved 3D tracking and automated classification of rodents’ behavioral activity using depth-sensing cameras". Behavior Research Methods (2020): https://doi.org/10.3758/s13428-020-01381-9.
    10.3758/s13428-020-01381-9
  17. Loureiro, J.; Torres, A.L.; Neto, T.; Aguiar, P.; Barrias, C.C.; Pinto, M.T.; Amaral, I.F.. "Corrigendum to “Conjugation of the T1 sequence from CCN1 to fibrin hydrogels for therapeutic vascularization” [Mater. Sci. & Eng. C. 104 (2019) 109847](S092849311930548X)(10.1016/j.msec.2019.109847)". Materials Science and Engineering C 108 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85076046977&partnerID=MN8TOARS.
    10.1016/j.msec.2019.110514
  18. Costa, A.R.; Sousa, S.C.; Pinto-Costa, R.; Mateus, J.C.; Lopes, C.D.; Costa, A.C.; Rosa, D.; et al. "The membrane periodic skeleton is an actomyosin network that regulates axonal diameter and conduction". eLife 9 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85082635132&partnerID=MN8TOARS.
    10.7554/eLife.55471
  19. Nunes, V.; Dantas, M.; Castro, D.; Vitiello, E.; Wang, I.; Carpi, N.; Balland, M.; et al. "Centrosome-nuclear axis repositioning drives the assembly of a bipolar spindle scaffold to ensure mitotic fidelity". Molecular Biology of the Cell 31 16 (2020): 1675-1690. http://www.scopus.com/inward/record.url?eid=2-s2.0-85088608180&partnerID=MN8TOARS.
    10.1091/mbc.E20-01-0047
  20. Castro, D.; Nunes, V.; Lima, J.T.; Ferreira, J.G.; Aguiar, P.; Castro, Domingos; Nunes, Vanessa; et al. "Trackosome: a computational toolbox to study the spatiotemporal dynamics of centrosomes, nuclear envelope and cellular membrane". Journal of Cell Science 133 24 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85099992997&partnerID=MN8TOARS.
    10.1101/2020.04.27.064204
  21. Kristine Heiney; José C. Mateus; Cátia D. F. Lopes; Estrela Neto; Meriem Lamghari; Paulo Aguiar; Heiney, K.; et al. "µSpikeHunter: An advanced computational tool for the analysis of neuronal communication and action potential propagation in microfluidic platforms". Scientific Reports (2019): https://doi.org/10.1038/s41598-019-42148-3.
    10.1038/s41598-019-42148-3
  22. José C Mateus; Cátia D F Lopes; Mónica Cerquido; Luís Leitão; Diana Leitão; Susana Cardoso; João Ventura; Paulo Aguiar. "Improved in vitro electrophysiology using 3D-structured microelectrode arrays with a micro-mushrooms islets architecture capable of promoting topotaxis". Journal of Neural Engineering (2019): https://doi.org/10.1088/1741-2552/ab0b86.
    10.1088/1741-2552/ab0b86
  23. Franco, N.H.; Gerós, A.; Oliveira, L.; Olsson, I.A.S.; Aguiar, P.. "ThermoLabAnimal - A high-throughput analysis software for non-invasive thermal assessment of laboratory mice". Physiology and Behavior 207 (2019): 113-121. http://www.scopus.com/inward/record.url?eid=2-s2.0-85065609959&partnerID=MN8TOARS.
    10.1016/j.physbeh.2019.05.004
  24. Aresta, G.; Araújo, T.; Kwok, S.; Chennamsetty, S.S.; Safwan, M.; Alex, V.; Marami, B.; et al. "BACH: Grand challenge on breast cancer histology images". Medical Image Analysis 56 (2019): 122-139. http://www.scopus.com/inward/record.url?eid=2-s2.0-85067343074&partnerID=MN8TOARS.
    10.1016/j.media.2019.05.010
  25. Leitão, L.; Alves, C.J.; Alencastre, I.S.; Sousa, D.M.; Neto, E.; Conceição, F.; Leitão, C.; et al. "Bone marrow cell response after injury and during early stage of regeneration is independent of the tissue-of-injury in 2 injury models". FASEB Journal 33 1 (2019): 857-872. http://www.scopus.com/inward/record.url?eid=2-s2.0-85059244844&partnerID=MN8TOARS.
    10.1096/fj.201800610RR
  26. Loureiro, J.; Torres, A.L.; Neto, T.; Aguiar, P.; Barrias, C.C.; Pinto, M.T.; Amaral, I.F.. "Conjugation of the T1 sequence from CCN1 to fibrin hydrogels for therapeutic vascularization". Materials Science and Engineering C 104 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85068767347&partnerID=MN8TOARS.
    10.1016/j.msec.2019.109847
  27. Catarina Dias; Luís M. Guerra; Paulo Aguiar; João Ventura. "The Concept of Metal-Insulator-Metal Nanostructures as Adaptive Neural Networks". U.Porto Journal of Engineering (2018): https://doi.org/10.24840/2183-6493_003.001_0001.
    10.24840/2183-6493_003.001_0001
  28. Fondón, I.; Sarmiento, A.; García, A.I.; Silvestre, M.; Eloy, C.; Polónia, A.; Aguiar, P.. "Automatic classification of tissue malignancy for breast carcinoma diagnosis". Computers in Biology and Medicine 96 (2018): 41-51. http://www.scopus.com/inward/record.url?eid=2-s2.0-85043461026&partnerID=MN8TOARS.
    10.1016/j.compbiomed.2018.03.003
  29. Horta, R.; Nascimento, R.; Gerós, A.; Aguiar, P.; Silva, A.; Amarante, J.. "A Novel System for Assessing Facial Muscle Movements: The Facegram 3D". Surgical Innovation 25 1 (2018): 90-92. http://www.scopus.com/inward/record.url?eid=2-s2.0-85040841966&partnerID=MN8TOARS.
    10.1177/1553350617753227
  30. Lopes, C.D.F.; Mateus, J.C.; Aguiar, P.. "Interfacing microfluidics with microelectrode arrays for studying neuronal communication and axonal signal propagation". Journal of Visualized Experiments 2018 142 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85058915521&partnerID=MN8TOARS.
    10.3791/58878
  31. Cerquido, M.; Proenca, M.P.; Dias, C.; Leitao, D.C.; Cardoso, S.; Freitas, P.P.; Aguiar, P.; Ventura, J.. "Tailoring the cap's morphology of electrodeposited gold micro-mushrooms". Applied Surface Science 445 (2018): 512-518. http://www.scopus.com/inward/record.url?eid=2-s2.0-85044588454&partnerID=MN8TOARS.
    10.1016/j.apsusc.2018.03.158
  32. Drpic, D.; Almeida, A.C.; Aguiar, P.; Renda, F.; Damas, J.; Lewin, H.A.; Larkin, D.M.; et al. "Chromosome Segregation Is Biased by Kinetochore Size". Current Biology 28 9 (2018): 1344-1356.e5. http://www.scopus.com/inward/record.url?eid=2-s2.0-85045880247&partnerID=MN8TOARS.
    10.1016/j.cub.2018.03.023
  33. Torres, A.L.; Bidarra, S.J.; Pinto, M.T.; Aguiar, P.C.; Silva, E.A.; Barrias, C.C.. "Guiding morphogenesis in cell-instructive microgels for therapeutic angiogenesis". Biomaterials 154 (2018): 34-47. http://www.scopus.com/inward/record.url?eid=2-s2.0-85032820887&partnerID=MN8TOARS.
    10.1016/j.biomaterials.2017.10.051
  34. Martins, L.F.; Costa, R.O.; Pedro, J.R.; Aguiar, P.; Serra, S.C.; Teixeira, F.G.; Sousa, N.; Salgado, A.J.; Almeida, R.D.. "Mesenchymal stem cells secretome-induced axonal outgrowth is mediated by BDNF". Scientific Reports 7 1 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85021292472&partnerID=MN8TOARS.
    10.1038/s41598-017-03592-1
  35. Mestre, A.L.G.; Inácio, P.M.C.; Elamine, Y.; Asgarifar, S.; Lourenço, A.S.; Cristiano, M.L.S.; Aguiar, P.; et al. "Extracellular electrophysiological measurements of cooperative signals in astrocytes populations". Frontiers in Neural Circuits 11 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85032285952&partnerID=MN8TOARS.
    10.3389/fncir.2017.00080
  36. Mestre, A.L.G.; Cerquido, M.; Inácio, P.M.C.; Asgarifar, S.; Lourenço, A.S.; Cristiano, M.L.S.; Aguiar, P.; et al. "Ultrasensitive gold micro-structured electrodes enabling the detection of extra-cellular long-lasting potentials in astrocytes populations". Scientific Reports 7 1 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85032462728&partnerID=MN8TOARS.
    10.1038/s41598-017-14697-y
  37. Shamarova, E.; Chertovskih, R.; Ramos, A.F.; Aguiar, P.. "Backward-stochastic-differential-equation approach to modeling of gene expression". Physical Review E 95 3 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85016463242&partnerID=MN8TOARS.
    10.1103/PhysRevE.95.032418
  38. Conde-Sousa, E.; Szücs, P.; Peng, H.; Aguiar, P.. "N3DFix: an Algorithm for Automatic Removal of Swelling Artifacts in Neuronal Reconstructions". Neuroinformatics 15 1 (2017): 5-12. http://www.scopus.com/inward/record.url?eid=2-s2.0-84978143735&partnerID=MN8TOARS.
    10.1007/s12021-016-9308-7
  39. Dias, C.; Lv, H.; Picos, R.; Aguiar, P.; Cardoso, S.; Freitas, P.P.; Ventura, J.. "Bipolar resistive switching in Si/Ag nanostructures". Applied Surface Science 424 (2017): 122-126. http://www.scopus.com/inward/record.url?eid=2-s2.0-85013683491&partnerID=MN8TOARS.
    10.1016/j.apsusc.2017.01.140
  40. Araujo, T.; Aresta, G.; Castro, E.; Rouco, J.; Aguiar, P.; Eloy, C.; Polonia, A.; Campilho, A.. "Classification of breast cancer histology images using convolutional neural networks". PLoS ONE 12 6 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85020032538&partnerID=MN8TOARS.
    10.1371/journal.pone.0177544
  41. Teixeira, G.Q.; Leite Pereira, C.; Castro, F.; Ferreira, J.R.; Gomez-Lazaro, M.; Aguiar, P.; Barbosa, M.A.; Neidlinger-Wilke, C.; Goncalves, R.M.. "Anti-inflammatory Chitosan/Poly-¿-glutamic acid nanoparticles control inflammation while remodeling extracellular matrix in degenerated intervertebral disc". Acta Biomaterialia 42 (2016): 168-179. http://www.scopus.com/inward/record.url?eid=2-s2.0-84983262266&partnerID=MN8TOARS.
    10.1016/j.actbio.2016.06.013
  42. Sousa, D.M.; Conceição, F.; Silva, D.I.; Leitão, L.; Neto, E.; Alves, C.J.; Alencastre, I.S.; et al. "Ablation of Y1 receptor impairs osteoclast bone-resorbing activity". Scientific Reports 6 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84988625216&partnerID=MN8TOARS.
    10.1038/srep33470
  43. Gerós, A.; Horta, R.; Aguiar, P.. "Facegram - Objective quantitative analysis in facial reconstructive surgery". Journal of Biomedical Informatics 61 (2016): 1-9. http://www.scopus.com/inward/record.url?eid=2-s2.0-84961616824&partnerID=MN8TOARS.
    10.1016/j.jbi.2016.03.011
  44. Alencastre, I.S.; Sousa, D.M.; Alves, C.J.; Leit�o, L.; Neto, E.; Aguiar, P.; Lamghari, M.. "Delivery of pharmaceutics to bone: Nanotechnologies, high-throughput processing and in silico mathematical models". European Cells and Materials 31 (2016): 355-381. http://www.scopus.com/inward/record.url?eid=2-s2.0-84973639341&partnerID=MN8TOARS.
  45. Lopes, C.D.F.; Gomes, C.P.; Neto, E.; Sampaio, P.; Aguiar, P.; Pêgo, A.P.. "Microfluidic-based platform to mimic the in vivo peripheral administration of neurotropic nanoparticles". Nanomedicine 11 24 (2016): 3205-3221. http://www.scopus.com/inward/record.url?eid=2-s2.0-84998705753&partnerID=MN8TOARS.
    10.2217/nnm-2016-0247
  46. Pereira, A.J.; Aguiar, P.; Belsley, M.; Maiato, H.. "Inducible fluorescent speckle microscopy". Journal of Cell Biology 212 2 (2016): 245-255. http://www.scopus.com/inward/record.url?eid=2-s2.0-84959490543&partnerID=MN8TOARS.
    10.1083/jcb.201506128
  47. Neto, E.; Leitão, L.; Sousa, D.M.; Alves, C.J.; Alencastre, I.S.; Aguiar, P.; Lamghari, M.. "Compartmentalized microfluidic platforms: The unrivaled breakthrough of in vitro tools for neurobiological research". Journal of Neuroscience 36 46 (2016): 11573-11584. http://www.scopus.com/inward/record.url?eid=2-s2.0-84996552043&partnerID=MN8TOARS.
    10.1523/JNEUROSCI.1748-16.2016
  48. Pereira, C.L.; Teixeira, G.Q.; Ribeiro-Machado, C.; Caldeira, J.; Costa, M.; Figueiredo, F.; Fernandes, R.; et al. "Mesenchymal Stem/Stromal Cells seeded on cartilaginous endplates promote Intervertebral Disc Regeneration through Extracellular Matrix Remodeling". Scientific Reports 6 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84988672665&partnerID=MN8TOARS.
    10.1038/srep33836
  49. Dias, C.; Guerra, L.M.; Ventura, J.; Aguiar, P.. "Memristor-based Willshaw network: Capacity and robustness to noise in the presence of defects". Applied Physics Letters 106 22 (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84930960301&partnerID=MN8TOARS.
    10.1063/1.4922148
  50. Silva, P.; Aguiar, P.; Duarte, R.; Davids, K.; Araújo, D.; Garganta, J.. "Effects of pitch size and skill level on tactical behaviours of association football players during small-sided and conditioned games". International Journal of Sports Science and Coaching 9 5 (2014): 993-1006. http://www.scopus.com/inward/record.url?eid=2-s2.0-84919760822&partnerID=MN8TOARS.
    10.1260/1747-9541.9.5.993
  51. Silva, P.; Travassos, B.; Vilar, L.; Aguiar, P.; Davids, K.; Araújo, D.; Garganta, J.. "Numerical relations and skill level constrain co-adaptive behaviors of agents in sports teams". PLoS ONE 9 9 (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84906991508&partnerID=MN8TOARS.
    10.1371/journal.pone.0107112
  52. Silva, P.; Duarte, R.; Sampaio, J.; Aguiar, P.; Davids, K.; Araújo, D.; Garganta, J.. "Field dimension and skill level constrain team tactical behaviours in small-sided and conditioned games in football". Journal of Sports Sciences 32 20 (2014): 1888-1896. http://www.scopus.com/inward/record.url?eid=2-s2.0-84918836662&partnerID=MN8TOARS.
    10.1080/02640414.2014.961950
  53. Horta, R.; Aguiar, P.; Silva, P.; Monteiro, D.; Amarante, J.M.. "Facial disfigurement: Restoration of facial dynamics in a patient with concomitant facial paralysis and blindness". Journal of Reconstructive Microsurgery 30 3 (2014): 207-210. http://www.scopus.com/inward/record.url?eid=2-s2.0-84896695594&partnerID=MN8TOARS.
    10.1055/s-0033-1357269
  54. Afonso, O.; Matos, I.; Pereira, A.J.; Aguiar, P.; Lampson, M.A.; Maiato, H.. "Feedback control of chromosome separation by a midzone Aurora B gradient". Science 345 6194 (2014): 332-336. http://www.scopus.com/inward/record.url?eid=2-s2.0-84904382634&partnerID=MN8TOARS.
    10.1126/science.1251121
  55. Sousa, M.; Szucs, P.; Lima, D.; Aguiar, P.. "The pronociceptive dorsal reticular nucleus contains mostly tonic neurons and shows a high prevalence of spontaneous activity in block preparation". Journal of Neurophysiology 111 7 (2014): 1507-1518. http://www.scopus.com/inward/record.url?eid=2-s2.0-84900810824&partnerID=MN8TOARS.
    10.1152/jn.00440.2013
  56. Sousa, M.; Aguiar, P.. "Building, simulating and visualizing large spiking neural networks with NeuralSyns". Neurocomputing 123 (2014): 372-380. http://www.scopus.com/inward/record.url?eid=2-s2.0-84885844080&partnerID=MN8TOARS.
    10.1016/j.neucom.2013.07.034
  57. Castro, L.; Aguiar, P.. "A feedforward model for the formation of a grid field where spatial information is provided solely from place cells". Biological Cybernetics 108 2 (2014): 133-143. http://www.scopus.com/inward/record.url?eid=2-s2.0-84898883716&partnerID=MN8TOARS.
    10.1007/s00422-013-0581-3
  58. Horta, R.; Aguiar, P.; Monteiro, D.; Silva, A.; Amarante, J.M.. "A facegram for spatial-temporal analysis of facial excursion: Applicability in the microsurgical reanimation of long-standing paralysis and pretransplantation". Journal of Cranio-Maxillofacial Surgery 42 7 (2014): 1250-1259. http://www.scopus.com/inward/record.url?eid=2-s2.0-84908230161&partnerID=MN8TOARS.
    10.1016/j.jcms.2014.03.006
  59. Barisic, M.; Aguiar, P.; Geley, S.; Maiato, H.. "Kinetochore motors drive congression of peripheral polar chromosomes by overcoming random arm-ejection forces". Nature Cell Biology 16 12 (2014): 1249-1256. http://www.scopus.com/inward/record.url?eid=2-s2.0-84925285786&partnerID=MN8TOARS.
    10.1038/ncb3060
  60. Neto, E.; Alves, C.J.; Sousa, D.M.; Alencastre, I.S.; Lourenço, A.H.; Leitão, L.; Ryu, H.R.; et al. "Sensory neurons and osteoblasts: Close partners in a microfluidic platform". Integrative Biology (United Kingdom) 6 6 (2014): 586-595. http://www.scopus.com/inward/record.url?eid=2-s2.0-84901624359&partnerID=MN8TOARS.
    10.1039/c4ib00035h
  61. Conde-Sousa, E.; Aguiar, P.. "A working memory model for serial order that stores information in the intrinsic excitability properties of neurons". Journal of Computational Neuroscience 35 2 (2013): 187-199. http://www.scopus.com/inward/record.url?eid=2-s2.0-84883784747&partnerID=MN8TOARS.
    10.1007/s10827-013-0447-7
  62. Moutinho-Pereira, S.; Stuurman, N.; Afonso, O.; Hornsveld, M.; Aguiar, P.; Goshima, G.; Vale, R.D.; Maiato, H.. "Genes involved in centrosome-independent mitotic spindle assembly in Drosophila S2 cells". Proceedings of the National Academy of Sciences of the United States of America 110 49 (2013): 19808-19813. http://www.scopus.com/inward/record.url?eid=2-s2.0-84889661951&partnerID=MN8TOARS.
    10.1073/pnas.1320013110
  63. Horta, R.; Monteiro, D.; Silva, A.; Amarante, J.M.; Aguiar, P.. "Erratum: Evaluation of a facial transplant candidate with a facegram: A baseline analysis (Plastic and Reconstructive Surgery (2013) 132 (479e-480))". Plastic and Reconstructive Surgery 132 4 (2013): 1040-1041. http://www.scopus.com/inward/record.url?eid=2-s2.0-84885454603&partnerID=MN8TOARS.
    10.1097/01.prs.0000435314.41811.85
  64. Szucs, P.; Luz, L.L.; Pinho, R.; Aguiar, P.; Antal, Z.; Tiong, S.Y.X.; Todd, A.J.; Safronov, B.V.. "Axon diversity of lamina I local-circuit neurons in the lumbar spinal cord". Journal of Comparative Neurology 521 12 (2013): 2719-2741. http://www.scopus.com/inward/record.url?eid=2-s2.0-84879484866&partnerID=MN8TOARS.
    10.1002/cne.23311
  65. Aguiar, P.; Horta, R.; Monteiro, D.; Silva, A.; Amarante, J.M.. "Evaluation of a facial transplant candidate with a facegram: A baseline analysis". Plastic and Reconstructive Surgery 132 3 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84883574434&partnerID=MN8TOARS.
    10.1097/PRS.0b013e31829ad4df
  66. Aguiar, P.; Sousa, M.; Szucs, P.. "Versatile morphometric analysis and visualization of the three-dimensional structure of neurons". Neuroinformatics 11 4 (2013): 393-403. http://www.scopus.com/inward/record.url?eid=2-s2.0-84886291005&partnerID=MN8TOARS.
    10.1007/s12021-013-9188-z
  67. Carneiro, J.; Duarte-Pereira, S.; Azevedo, L.; Castro, L.F.C.; Aguiar, P.; Moreira, I.S.; Amorim, A.; Silva, R.M.. "The Evolutionary Portrait of Metazoan NAD Salvage". PLoS ONE 8 5 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84878391235&partnerID=MN8TOARS.
    10.1371/journal.pone.0064674
  68. Silva, P.; Garganta, J.; Araújo, D.; Davids, K.; Aguiar, P.. "Shared knowledge or shared affordances? insights from an ecological dynamics approach to team coordination in sports". Sports Medicine 43 9 (2013): 765-772. http://www.scopus.com/inward/record.url?eid=2-s2.0-84883221144&partnerID=MN8TOARS.
    10.1007/s40279-013-0070-9
  69. Guimarães, J.; Moura, E.; Silva, E.; Aguiar, P.; Garrett, C.; Vieira-Coelho, M.A.. "Locus coeruleus is involved in weight loss in a rat model of Parkinson's disease: An effect reversed by deep brain stimulation". Brain Stimulation 6 6 (2013): 845-855. http://www.scopus.com/inward/record.url?eid=2-s2.0-84887990923&partnerID=MN8TOARS.
    10.1016/j.brs.2013.06.002
  70. Conde-Sousa E; Aguiar P; Conde-Sousa, Eduardo; Aguiar, Paulo. "Conversion from spatial patterns of activity to sequences of neuronal activations using gate interneurons.". BMC Neuroscience 14 S1 (2013): http://europepmc.org/abstract/PMC/PMC3704592.
    10.1186/1471-2202-14-s1-p3
  71. Castro, L.; Aguiar, P.. "Phase precession through acceleration of local theta rhythm: A biophysical model for the interaction between place cells and local inhibitory neurons". Journal of Computational Neuroscience 33 1 (2012): 141-150. http://www.scopus.com/inward/record.url?eid=2-s2.0-84861878587&partnerID=MN8TOARS.
    10.1007/s10827-011-0378-0
  72. Pinto, S.; Krishna, R.; Dias, C.; Pimentel, G.; Oliveira, G.N.P.; Teixeira, J.M.; Aguiar, P.; et al. "Resistive switching and activity-dependent modifications in Ni-doped graphene oxide thin films". Applied Physics Letters 101 6 (2012): http://www.scopus.com/inward/record.url?eid=2-s2.0-84865141673&partnerID=MN8TOARS.
    10.1063/1.4742912
  73. Pais-Vieira, M.; Aguiar, P.; Lima, D.; Galhardo, V.. "Inflammatory pain disrupts the orbitofrontal neuronal activity and risk-assessment performance in a rodent decision-making task". Pain 153 8 (2012): 1625-1635. http://www.scopus.com/inward/record.url?eid=2-s2.0-84863720383&partnerID=MN8TOARS.
    10.1016/j.pain.2012.04.011
  74. Aguiar, P.; Sousa, M.; Lima, D.. "NMDA channels together with L-type calcium currents and calcium-activated nonspecific cationic currents are sufficient to generate windup in WDR neurons". Journal of Neurophysiology 104 2 (2010): 1155-1166. http://www.scopus.com/inward/record.url?eid=2-s2.0-77955972258&partnerID=MN8TOARS.
    10.1152/jn.00834.2009
  75. Vourvouhaki, E.; Carvalho, C.; Aguiar, P.. "Model for Osteosarcoma-9 as a potent factor in cell survival and resistance to apoptosis". Physical Review E - Statistical, Nonlinear, and Soft Matter Physics 76 1 (2007): http://www.scopus.com/inward/record.url?eid=2-s2.0-34547619785&partnerID=MN8TOARS.
    10.1103/PhysRevE.76.011926
  76. Aguiar, P.; Mendonça, L.; Galhardo, V.. "OpenControl: A free opensource software for video tracking and automated control of behavioral mazes". Journal of Neuroscience Methods 166 1 (2007): 66-72. http://www.scopus.com/inward/record.url?eid=2-s2.0-34548491369&partnerID=MN8TOARS.
    10.1016/j.jneumeth.2007.06.020
  77. Aguiar, P.; Willshaw, D.. "Hippocampal mossy fibre boutons as dynamical synapses". Neurocomputing 58-60 (2004): 699-703. http://www.scopus.com/inward/record.url?eid=2-s2.0-2542481831&partnerID=MN8TOARS.
    10.1016/j.neucom.2004.01.116
Capítulo de livro
  1. Dias, C.; Silva, D.J.; Aguiar, P.; Ventura, J.. "Associative networks and perceptron based on memristors: Fundamentals and algorithmic implementation". 729-765. 2019.
  2. Dias, C.; Ventura, J.; Aguiar, P.. "Memristive-based neuromorphic applications and associative memories". 2017.
    10.1007/978-3-319-51724-7_13
  3. Neto, E.; Paramos-De-Carvalho, D.; Lourenço, A.H.; Aguiar, P.; Lamghari, M.. "Compartmentalized microfluidic platforms as tool of choice to study the interaction between neurons and osteoblasts". 2015.
    10.1007/978-1-4939-2510-0_10
Poster em conferência
  1. Sousa, Sara Castro; Aroso, Miguel; Veríssimo, Eduardo; Brites, Pedro; Vieira, Jorge; Cristina P. Vieira ; Aguiar, Paulo; Sousa, Monica M. Autor correspondente: Sousa, Monica M. "Tension-driven growth triggers developmental stage-specific adaptations of the axonal cytoskeleton and membrane". Trabalho apresentado em Forces Across Scales - i3S, University of Porto, Portugal, 2024.
  2. Terceiro, Ana F.; Lobo, Andrea; Canedo, Teresa; Socodato, Renato; Carvalhais, Lia; Aroso, Miguel; Sousa, Mafalda; et al. "Rho GTPases in the spotlight: unveiling methamphetamine's effects on neuronal remodeling in the hippocampus". Trabalho apresentado em Neuroscience 2023, 2023.
  3. Silva, SC; Castro, Domingos; MATEUS, JOSÉ C; Aroso, Miguel; Aguiar, Paulo. Autor correspondente: Aguiar, Paulo. "A Tripartite Microfluidic Device with Integrated Microelectrodes to Study the Neuron-Astrocyte Crosstalk". Trabalho apresentado em VII Symposium of the Portuguese Glial Network, 2023.
  4. Castro, Domingos; Aroso, Miguel; A. Pedro Aguiar; David B. Grayden; Aguiar, Paulo. "Disrupting unwanted neuronal oscillations with closed-loop". Trabalho apresentado em NER IEEE 2023, 11th International IEEE EMBS Conference on Neural, 2023.
  5. Terceiro, Ana F.; Lobo, Andrea; Canedo, Teresa; Carvalhais, Lia; Aroso, Miguel; Sousa, Mafalda; Socodato, Renato; et al. "Methamphetamine-induced modulation of RhoGTPases in hippocampal neurons and microglia (Presented by A. Terceiro)". Trabalho apresentado em n FENS-Hertie Winter School on Neuro-Immune Interactions in Health and Disease, 2023.
  6. Castro, Domingos; Aroso, Miguel; A. Pedro Aguiar; David B. Grayden; Aguiar, Paulo. "Disrupting pathological neuronal oscillations with closed-loop stimulation in vitro". Trabalho apresentado em Nature Conference - Technologies for Neuroengineering 2022, 2022.
  7. Silva, SC; Castro, Domingos; MATEUS, JOSÉ C; Aroso, Miguel; Aguiar, Paulo. Autor correspondente: Aguiar, Paulo. "Electrical Stimulation of Astrocytes and its Impact on Astrocytic Calcium Signaling". Trabalho apresentado em VI Symposium of the Portuguese Glia Network, 2022.
  8. Terceiro, Ana F.; Lobo, Andrea; Canedo, Teresa; Carvalhais, Lia; Aroso, Miguel; Sousa, Mafalda; Magalhães, Ana; et al. ""Methamphetamine remodelling of hippocampal neurons is orchestrated via cdc42 pathway (Presented by A. Terceiro)". Trabalho apresentado em VI Symposium of the Portuguese Glial Network, 2022.
  9. Domingos Leite de Castro; Aroso, Miguel; Aguiar, A. Pedro; David B. Grayden; Aguiar, Paulo. Autor correspondente: Domingos Leite de Castro. "Disrupting periodic neuronal synchrony with closed-loop stimulation in vitro". Trabalho apresentado em Cosyne 2022, 2022.
  10. Catarina Dias; Domingos Castro; Aroso, Miguel; João Ventura; Aguiar, Paulo. Autor correspondente: Catarina Dias. "Bio/electronic interfaces for neuroprosthetics". Trabalho apresentado em 3rd Condensed Matter Physics National Conference, 2022.
  11. Lobo, Andrea; Ana Filipa Terceiro; Lia Carvalhais; Aroso, Miguel; Mafalda Sousa; Ana Magalhães; Aguiar, Paulo; Relvas, João; Summavielle, Teresa. "Methamphetamine remodelling of hippocampal neurons is orchestrated via cdc42 pathway". Trabalho apresentado em XVII Meeting of the Portuguese Society for Neuroscience - SPN2021, 2021.
  12. Catarina Dias; Domingos Castro; Aroso, Miguel; João Ventura; Aguiar, Paulo. "A neuromorphic system for real-time feedback stimulation of neuronal populations". Trabalho apresentado em XVII Meeting of the Portuguese Society for Neuroscience - SPN2021, 2021.
  13. Mateus JC; Lopes, CDF; Aroso, Miguel; Costa AR; Gerós, Ana; Meneses J; Faria P; et al. "New insights into the mechanisms regulating axonal development and maturation". Trabalho apresentado em XVII Meeting of the Portuguese Society for Neuroscience - SPN2021, 2021.
  14. Aroso, Miguel; Domingos Castro; Sara Silva; Leonor Sá; Aguiar, Paulo. Autor correspondente: Aroso, Miguel. "Astrocytes are activated by direct electrical stimulation in the physiological range of neuronal activity". Trabalho apresentado em XVII Meeting of the Portuguese Society for Neuroscience - SPN2021, 2021.
  15. Lopes, CDF; Catarina Ricardo; Maria Ribeiro; José Mateus; Aroso, Miguel; Aguiar, Paulo. Autor correspondente: Aguiar, Paulo. "Dissecting the regulatory effects of neuronal electrical activity on mitochondria axonal transport dynamics". Trabalho apresentado em XVII Meeting of the Portuguese Society for Neuroscience - SPN2021, 2021.
  16. Catarina Dias; Domingos Castro; Aroso, Miguel; João Ventura; Aguiar, Paulo. Autor correspondente: Catarina Dias. "A bio-electronic memristive interface for real-time coupling of neuronal populations". Trabalho apresentado em 4th International Conference on Memristive Materials, Devices & Systems (MEMRISYS 2021), 2021.
  17. Sara Castro Sousa; Aroso, Miguel; Tiago Silva; Lopes, CDF; Pedro Brites; Aguiar, Paulo; Sousa, Monica M. "A microfluidic platform enabling live imaging of cytoskeleton dynamics and transport of axon elongation driven by physiological stretch". Trabalho apresentado em The EMBO Workshop Axons 2021: Structure and Function, 2021.
  18. Catarina Dias; Domingos Castro; Aroso, Miguel; João Ventura; Aguiar, Paulo. "Real-time adaptive coupling between neuronal populations in a hybrid bio-electronic interface using memristors". Trabalho apresentado em Nature Conference- Technologies for Neuroengineering, 2021.
  19. Aroso, Miguel; Silva, SC; Aguiar, Paulo. "Enlightening the Neuron-Astrocytes Interaction in the Electrophysiological Domain: Astrocytic Calcium Waves in Response to Electrical Stimuli". Trabalho apresentado em 8th i3S Annual Meeting, 2019.
  20. Silva, SC; Aguiar, Paulo; Aroso, Miguel. "Assessing Functional Activity of Astrocytes by Calcium Imaging: Astrocytic Calcium Signals and the Electrophysiological Environment". Trabalho apresentado em XVI Meeting of the Portuguese Society for Neuroscience, 2019.
  21. Conceição, Francisco; Daniela M. Sousa; Alves, Cecília J; I. S. Alencastre; Aguiar, Paulo; Lamghari, Meriem. "The Deficiency of Y1 Receptor Signalling Leads to Defective Osteoclast Bone-Resorbing Activity". Trabalho apresentado em GPCR-Ligand Interactions, Structures, and Transmembrane Signalling: a European Research Network (GLISTEN) Symposium, 2017.
  22. Conceição, Francisco; Daniela M. Sousa; Aguiar, Paulo; Lamghari, Meriem. "A Computational Tool for Bone Resorption Analysis". Trabalho apresentado em 4th International Symposium in applied Bioimaging, 2015.
  23. Luz, Liliana Laracho; Pinho, Raquel; Aguiar, Paulo; Antal, Zsófia; Todd, Andrew J.; Safronov, Boris V.; Szucs, Peter. "Morphological analysis of lamina I local-circuit neurons in the lumbar spinal cord of the rat". Trabalho apresentado em Champalimaud Neuroscience Symposium, 2011.
  24. Cardoso-Cruz, Helder; Aguiar, Paulo; Lima, Deolinda; Galhardo, Vasco. "Thalamocortical global dynamics of behavioral transitions in a rat model of persistent peripheral neuropathic pain". Trabalho apresentado em X Reunião Annual da Sociedade Portuguesa de Neurociências. 2007, 24-26 Maio, Ofir, PORTUGAL., 2007.
Pré-impressão
  1. Miguel Aroso; Domingos Castro; Sara Costa Silva; Paulo Aguiar. "Bringing astrocytes into the spotlight of electrical brain stimulation". 2024. https://doi.org/10.1101/2024.02.28.582466.
    10.1101/2024.02.28.582466
  2. Andreia M. Oliveira; Eduardo Carvalho; Beatriz Barros; Carolina Soares; Manuel Ferreira-Pinto; Rui Vaz; Paulo Aguiar. "DBScope: a versatile computational toolbox for the visualization and analysis of sensing data from Deep Brain Stimulation". 2023. https://doi.org/10.1101/2023.07.23.23292136.
    10.1101/2023.07.23.23292136
  3. Domingos Leite de Castro; Miguel Aroso; A. Pedro Aguiar; David B. Grayden; Paulo Aguiar. "Adaptive delayed feedback control disrupts unwanted neuronal oscillations and adjusts to network synchronization dynamics". 2022. https://doi.org/10.1101/2022.07.05.498735.
    10.1101/2022.07.05.498735
  4. Ana Gerós; Ricardo Cruz; Fabrice de Chaumont; Jaime S. Cardoso; Paulo Aguiar. "Deep learning-based system for real-time behavior recognition and closed-loop control of behavioral mazes using depth sensing". 2022. https://doi.org/10.1101/2022.02.22.481410.
    10.1101/2022.02.22.481410
  5. Margarida Dantas; Andreia Oliveira; Paulo Aguiar; Helder Maiato; Jorge G. Ferreira. "Mechanosensitive control of mitotic entry". 2021. https://doi.org/10.1101/2021.09.23.461473.
    10.1101/2021.09.23.461473
Resumo em conferência
  1. Sousa, Sara Castro; Aroso, Miguel; 5E1D-7E42-BBAD; Veríssimo, Eduardo; Brites, Pedro; Aguiar, Paulo; Sousa, Monica M; Lopes, CDF. "Tension-driven axon elongation triggers cytoskeleton and membrane remodelling". Trabalho apresentado em IUBMB-EMBO Focused Meeting On Emerging Concepts Of The Neuronal Cytoskeleton (6th Edition), Santa Cruz, 2023.
  2. Loureiro, Joana C.; Torres, Ana L.; Neto, Tânia; Aguiar, Paulo; Barrias, Cristina C.; Pinto, Marta T.; Amaral, Isabel F.. "Pro-angiogenic effect of fibrin hydrogel functionalization with the T1 sequence from CCN1". Trabalho apresentado em Second CellFit Workshop (COST Action CA16119), Belgrade, 2019.
  3. Loureiro, Joana C.; Torres, Ana L.; Aguiar, Paulo; Pinto, Marta T.; Amaral, Isabel F.. "Conjugation of the integrin a6ß1 binding domain of the angiogenic inducer CCN1 to fibrin hydrogels for therapeutic vascularization". Trabalho apresentado em 28th Annual Conference of the European Society for Biomaterials (ESB), Athens, 2017.
  4. Loureiro, Joana C.; Torres, Ana L.; Aguiar, Paulo; Pinto, Marta T.; Amaral, Isabel F.. "Fibrin hydrogels functionalized with integrin-specific adhesive cues for therapeutic vascularization in the central nervous system". Trabalho apresentado em XV Annual Meeting of the Portuguese Society for Neuroscience, Braga, 2017.
  5. Monteiro, João P.; Oliveira, Hélder P.; Aguiar, Paulo; Cardoso, Jaime S.. "Depth-map Images for Automatic Mice Behavior Recognition". Trabalho apresentado em 1st PhD. Students Conference in Electrical and Computer Engineering, Porto, 2012.
    Publicado

Outros

Conjunto de dados
  1. BACH Dataset : Grand Challenge on Breast Cancer Histology images.
    10.5281/zenodo.3632035
  2. RGB-D Rat Behavioral Dataset.
    10.5281/zenodo.3636136
  3. MATEUS, JOSÉ C; Aguiar, Paulo. Sample raw data for publication "Bidirectional flow of action potentials in axons drives activity dynamics in neuronal cultures".
    10.5281/zenodo.5745979
Outra produção
  1. Nanoparticles Targeting Sialyl-Tn for Tyrosine Kinase Inhibitor Efficient Delivery in Gastric Cancer. 2023. Diniz, F.; Lamas, S.; Osório, H.; Aguiar, P.; Freitas, D.; Gartner, F.; Sarmento, B.; Reis, C.A.; Gomes, J.. http://www.scopus.com/inward/record.url?eid=2-s2.0-85147570161&partnerID=MN8TOARS.
    10.2139/ssrn.4347869
  2. A memristor-based neuromodulation device for real-time monitoring and adaptive control of in vitro neuronal populations. 2021. Catarina Dias; Domingos Castro; Miguel Aroso; João Ventura; Paulo Aguiar. https://doi.org/10.1101/2021.05.20.444941.
    10.1101/2021.05.20.444941
  3. In vitro neuronal networks show bidirectional axonal conduction with antidromic action potentials effectively depolarizing the soma. 2021. Mateus, J.C.; Lopes, C.D.F.; Aroso, M.; Costa, A.R.; Gerós, A.; Pereira, A.; Meneses, J.; et al. http://www.scopus.com/inward/record.url?eid=2-s2.0-85105400648&partnerID=MN8TOARS.
    10.1101/2021.03.07.434278
  4. Kinetochore-mediated microtubule assembly and Augmin-dependent amplification drive k-fiber maturation in mammals. 2021. Almeida, A.C.; Oliveira, J.; Drpic, D.; Cheeseman, L.P.; Damas, J.; Lewin, H.A.; Larkin, D.M.; et al. http://www.scopus.com/inward/record.url?eid=2-s2.0-85118903356&partnerID=MN8TOARS.
    10.1101/2021.08.18.456780
  5. HEROHE Challenge: Assessing HER2 status in breast cancer without immunohistochemistry or in situ hybridization. 2021. Conde-Sousa, E.; Vale, J.; Feng, M.; Xu, K.; Wang, Y.; Mea, V.D.; Barbera, D.L.; et al. http://www.scopus.com/inward/record.url?eid=2-s2.0-85169487309&partnerID=MN8TOARS.
    10.48550/arxiv.2111.04738
  6. Mechanosensitive nuclear asymmetries define a bipolar spindle scaffold to ensure mitotic fidelity. 2019. Nunes, V.; Dantas, M.; Castro, D.; Vitiello, E.; Wang, I.; Carpi, N.; Balland, M.; et al. http://www.scopus.com/inward/record.url?eid=2-s2.0-85095641297&partnerID=MN8TOARS.
    10.2139/ssrn.3434727
  7. Sensory neurons sprouting is dependent on osteoclast-derived extracellular vesicles involving the activation of epidermal growth factor receptors. 2018. Estrela Neto; Luís Leitão; José Mateus; Daniela M. Sousa; Francisco Conceição; Cecília J. Alves; Richard O. C. Oreffo; et al. https://doi.org/10.1101/259218.
    10.1101/259218
Atividades

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação) 		Instituição / Organização
2017 - Atual Workshop on Neuroengineering (2017)
Oficina (workshop) (Presidente da Comissão Organizadora)
2018 - 2019 Future of Computing (2018 - 2019)
Oficina (workshop) (Coorganizador)
2014 - 2016 International Symposium in Applied Bioimaging (2014 - 2016)
Simpósio (Coorganizador)

Júri de grau académico

Tema
Tipo de participação 		Nome do candidato (Tipo de grau)
Instituição / Organização
2019 Transcutaneous spinal direct current stimulation: modelling the spinal electric field distribution and clinical relevance
Arguente
 Sofia Rita Fernandes (Doutoramento)
Universidade de Lisboa Instituto de Biofísica e Engenharia Biomédica, Portugal
2016 LocoMouse: a novel system for studying the role of cerebellum in gait coordination
Arguente
 Ana Sofia Rodrigues Machado (Doutoramento)
2014 Multi-bump solutions in dynamic neural fields: Analysis and Applications
Arguente principal
 Flora Ferreira (Doutoramento)
2014 Efficient storage and retrieval of memories in neural networks
Arguente principal
 João Sacramento (Doutoramento)
Instituto Superior Técnico Departamento de Física, Portugal
2009 Numerical modelling in Transcranial Magnetic Stimulation
Arguente principal
 Ricardo Salvador (Doutoramento)

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2020 - Atual Introduction to Python and Fundamental Concepts in Machine Learning (Outros) Universidade do Porto, Portugal
2017 - Atual Neuroengineering (Mestrado integrado) Universidade do Porto Faculdade de Engenharia, Portugal
2010 - 2020 Introduction to Scientific Programming with MATLAB (Outros)
2016 - 2018 NEUBIAS - International school on bioimage analysis
2014 - 2018 Medical Biophysics (Mestrado integrado)
2016 - 2017 CAJAL Course in Computational Neuroscience Programa Champalimaud de Neurociências, Portugal
2008 - 2017 Computational Neuroscience (Doutoramento) Universidade do Porto Faculdade de Medicina, Portugal
2008 - 2012 Mathematics in Biology; Computational Biology (Mestrado) Universidade do Porto Faculdade de Ciências, Portugal
2002 - 2004 Teaching Assistant (in M.Sc. courses): 1) "Neural Computation"; 2) "Learning from Data"; 3) "Maths Refresher" (Master) The University of Edinburgh Institute for Adaptive and Neural Computation, Reino Unido
1998 - 2000 Teaching Assistant (in B.Sc. courses): 1) "Physics II"; 2) "Computational Physics" (Bacharelato)

Membro de associação

Nome da associação Tipo de participação
2006 - Atual Sociedade Portuguesa de Neurociências
1999 - 2000 NFIST Astronomy Group Director

Membro de comissão

Descrição da atividade
Tipo de participação 		Instituição / Organização
2019 - Atual Vice-Coordinator of the Neurobiology and Neurologic Disorders (NDD) Integrative Program at i3S
Coordenador
 Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2000 - 2001 IST Physics Degree Committee (only non-Professor member)
Membro