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João C. Paquete-Ferreira graduated in 2017 with a BSc. in Biochemistry and, more recently, finished an MSc. in Biochemistry (2019), both granted by Faculdade de Ciências e Tecnologia Universidade Nova de Lisboa (FCT-NOVA). The main scientific interests of Paquete-Ferreira are the production of protein for determination of their structures, using X-ray Crystallography, for the rational development of new drugs, and the biophysical characterization of protein-ligand interactions. At the end of his BSc, he enrolled in the Macromolecular Crystallography Lab UCIBIO @REQUIMTE (FCT-NOVA), where he developed his first research activities, contacting with different techniques, giving him the knowledge to overexpress, purify and crystalize a protein, as well, as characterize it with diverse biophysical techniques. Paquete-Ferreira developed his master’s thesis, also in the Macromolecular Crystallography Lab, being able to solve the first reported three-dimensional structure of an LCP protein from Streptococcus dysgalactiae subs. dysgalactiae and extensively studied the interaction of the protein with different ligands. Also, during his master’s thesis, Paquete-Ferreira was involved in another project regarding the anti-apoptotic Bcl-2 protein, that is overexpressed in tumours leading to resistance to chemotherapeutic agents. From is participation in this project resulted in his first scientific publication. Among the experimental activities, communication in science was an important part as well, resulting in two oral communications with one of them being held at VIII Encontro Nacional de Utilzadores de Radiação de Sincrotrão (ENURS). These experiences improve his ability to communicate and perform a presentation that is pleasant to assist for a scientific audience. Paquete-Ferreira activities go beyond the scientific environment, as he is an active member of the community. He was involved in different organizations within the bachelor’s degree of Biochemistry that aims to improve the academic experience of the students. Taken together, Paquete-Ferreira experiences and skills make him a valuable asset to be part of a research team.
Identification

Personal identification

Full name
João Carlos Paquete Ferreira
Date of birth
1996/04/30
Gender
Male

Citation names

  • Paquete-Ferreira, João
  • Paquete-Ferreira, João C.
  • Paquete-Ferreira, J. C.

Author identifiers

Ciência ID
9E13-6E78-66FF
ORCID iD
0000-0003-2846-6606

Websites

  • https://www.linkedin.com/in/jo%C3%A3o-paquete-ferreira-a50258b1/ (Professional)

Knowledge fields

  • Natural sciences - Biological Sciences - Biochemistry
  • Natural sciences - Biological Sciences - Biophysics
  • Natural sciences - Biological Sciences - Biochemical Research Methods
  • Exact Sciences - Computer and Information Sciences - Bioinformatics
  • Medical and Health Sciences - Health Sciences - Infectious Diseases

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Proficiency (C2) Advanced (C1) Intermediate (B1) Intermediate (B1)
French Beginner (A1) Elementary (A2) Beginner (A1) Beginner (A1) Beginner (A1)
Education
Degree Classification
2021/01/01 - 2025/01/01
Ongoing
Doctoral Programme of Biochemistry (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2020/03 - 2020/07
Concluded
Getting started in cryo-EM (Outros)
California Institute of Technology, United States
2019/12 - 2020/02
Concluded
Learn to Program: The Fundamentals (Outros)
University of Toronto Department of Computer Science, Canada
2017/09 - 2019/10
Concluded
Msc in Biochemistry (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
"LytR Inhibition, an Approach to Avoid Biofilm Formation in Streptococcus dysgalactiae subs. dysgalactiae" (THESIS/DISSERTATION)
2014/09 - 2017/06
Concluded
Bsc in Biochemistry (Licenciatura)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
"Análise Estrutural e Funcional de uma Proteína Envolvida na Formação de Biofilmes para Desenvolvimento de Fármacos" (THESIS/DISSERTATION)
Affiliation

Science

Category
Host institution
Employer
2021/01/01 - 2025/01/01 Research Trainee (Research) REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2018/07 - 2019/09 Research Trainee (Research) REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
Outputs

Publications

Journal article
  1. Alves-Barroco, Cinthia; Paquete-Ferreira, João; Santos-Silva, Teresa; Fernandes, Alexandra R.. "Singularities of Pyogenic Streptococcal Biofilms – From Formation to Health Implication". Frontiers in Microbiology 11 (2020): http://dx.doi.org/10.3389/fmicb.2020.584947.
    Published • 10.3389/fmicb.2020.584947
  2. João Ramos; Jayaraman Muthukumaran; Freire, Filipe; Ferreira, João; Ana Rita Otrelo-Cardoso; Dmitri Svergun; Alejandro Panjkovich; Teresa, Santos-Silva. "Shedding Light on the Interaction of Human Anti-Apoptotic Bcl-2 Protein with Ligands through Biophysical and in Silico Studies". International Journal of Molecular Sciences (2019): http://dx.doi.org/10.3390/ijms20040860.
    Published • 10.3390/ijms20040860
Thesis / Dissertation
  1. Paquete-Ferreira, João. "LytR Inhibition, as a New Approach to Avoid Biofilm Formation in Streptococcus dysgalactiae subs. dysgalactiae". Master, Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, 2019. https://drive.google.com/open?id=1KxvUWIP9IQh13Al6ruYvM0-s1e3TaaTI (~15 minutes video).
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2019/06/28 LytR from Streptococcus dysgalactiae subs. dysgalactiae: A Target for Biofilm Inhibition Presentation video (~10 minutes): https://drive.google.com/open?id=1lqgZa1RGyi4UOnaKXovbA7u_6PwJqbf3 VIII Encontro Nacional de Utilizadores de Radiação de Sincrotrão
Universidade do Porto, Faculdade de Ciências (Porto, Portugal)
2019/02/15 Structure-Based Desing of Promising Antibiofilm Formation Molecules Jornadas Intercalares das Dissertações Anuais dos Mestrados do DQ e do DCV
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia (Caparica, Portugal)

Event organisation

Event name
Type of event (Role)
Institution / Organization
2019/04/24 - 2019/04/24 Volunteer in the annual presentation event of Faculdade de Ciências e Tecnologia educational offer (EXPO-FCT), which aims to provide orientation to pre-university students, when choosing a higher education course, through scientific demonstrations and workshop activities. As well, as demonstrate to the community, it's innovative research in the different fields. (2019/04/24 - 2019/04/24)
Exhibition (Other)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2016/11 - 2017/02 JorTec - Jornadas Tecnológicas da Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa – it is an event open to all people (inside and outsider FCT/NOVA), either students, professors, investigators and/or companies. It takes place at the FCT campus in Monte de Caparica and is organized exclusively by students from FCT-NOVA. The biggest objective of JorTec is to let know to all the participants the different realities existing in the several different areas of the faculty. (2017/02/03 - 2017/02/10)
Conference (President of the Organising Committee)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2016/04/06 - 2016/04/06 Volunteer in the annual presentation event of Faculdade de Ciências e Tecnologia educational offer (EXPO-FCT), which aims to provide orientation to pre-university students, when choosing a higher education course, through scientific demonstrations and workshop activities. As well, as demonstrate to the community, it's innovative research in the different fields. (2016/04/06 - 2016/04/06)
Exhibition (Other)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2015/11 - 2016/02 JorTec - Jornadas Tecnológicas da Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa – it is an event open to all people (inside and outsider FCT/NOVA), either students, professors, investigators and/or companies. It takes place at the FCT campus in Monte de Caparica and is organized exclusively by students from FCT-NOVA. The biggest objective of JorTec is to let know to all the participants the different realities existing in the several different areas of the faculty. (2016/01/29 - 2016/02/05)
Conference (Member of the Organising Committee)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Event participation

Activity description
Type of event
Event name
Institution / Organization
2015/02/13 - 2015/02/13 JorTec - Jornadas Tecnológicas da Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa – it is an event open to all people (inside and outsider FCT/NOVA), either students, professors, investigators and/or companies. It takes place at the FCT campus in Monte de Caparica and is organized exclusively by students from FCT-NOVA. The biggest objective of JorTec is to let know to all the participants the different realities existing in the several different areas of the faculty.
Conference
JORTEC Química e Bioquímica - Química à Portuguesa
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Committee member

Activity description
Role
Institution / Organization
2016/11 - 2017/06 Treasurer at Núcleo de Estudantes de Bioquímica FCT-NOVA (NuBioq). NuBioq was funded in 2016 by a group of students that aim to organize dynamic activities associated with the bachelor degree of Biochemistry. The activities organized by NuBioq enrich the academic experience of the students through workshops and lectures among other activities.
Member
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2015/04 - 2016/03 The pedagogical commission main objective is to facilitate the communication between the students and professors of the Biochemistry graduation of FCT-NOVA. It is also the linkage unit between the Biochemistry degree e the exterior providing important information, like scholarships, lectures and workshops; and revealing the degree in several institutions for the students to develop projects or ideas.
Member
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal