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João Paulo Caseiro Baixinho holds a a B.Sc. in Cellular and Molecular Biology (2016) and M.Sc. in Biotechnology (2018) from Faculdade de Ciências e Tecnologias da Universidade Nova de Lisboa. His master's thesis project, focused on the development of curcumin lipid formulations for food applications, was developed at the Nutraceuticals & Bioactives Process Lab of the Food & Health Division, at iBET and ITQB-NOVA (Oeiras, Portugal). As a Research Fellow working in the Food & Health Division of iBET, his research focused on using the by-products resulting from agro-industrial waste streams, in a perspective of its valorisation, through the achievement of technology advances in terms of extraction, fractionation and purification processes at the industrial level. The aim is to use of green extraction technologies to obtain extracts and compounds from chicory waste streams to unravel their bioactive potential by applying several analytical and biochemical tools. In 2022 started is PhD focused on the valorisation of winery waste streams: towards a bio-based novel pesticides. Focused on waste valorisation, circular economy and sustainable production chain. João Baixinho has two oral and three poster presentations at conferences where he won a prize for best poster presentation. Participated in the training school: Basic principles of supercritical fluids and actual trends on high pressure and is specialized in the valorization of agri-food waste through the use of green technologies.
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Identification

Personal identification

Full name
João Paulo Caseiro Baixinho

Citation names

  • Baixinho, João
  • Baixinho, J. C.

Author identifiers

Ciência ID
821E-8BB8-BC56
ORCID iD
0000-0002-0610-7664

Email addresses

  • jbaixinho@ibet.pt (Professional)

Telephones

Mobile phone
  • 919179553 (Personal)

Addresses

  • Plataforma Tecnológica (iBET), Av da Republica, Quinta do Marquês, 2780-157, Oeiras, Oeiras, Portugal (Professional)

Knowledge fields

  • Natural sciences - Biological Sciences
  • Engineering and Technology - Industrial Biotechnology - Bioproducts Biomaterials

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Education
Degree Classification
2022/01/01 - 2025/12/31
Ongoing
 Química Sustentável (Doutoramento)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
"Valorisation of winery waste streams: towards a bio-based novel pesticides" (THESIS/DISSERTATION)
2016/09 - 2018/11
Concluded
 Biotecnologia (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
"Development of curcumin lipid formulations for food applications: transport, permeability and safety evaluation on a mucus-secreting intestinal epithelial cell model" (THESIS/DISSERTATION)
 15
2013/09 - 2016/07
Concluded
 Biologia Celular e Molecular (Licenciatura)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
 14
Affiliation

Science

Category
Host institution 		Employer
2018/12 - 2021/12/31 Researcher (Research) Instituto de Biologia Experimental e Tecnológica, Portugal
Instituto de Biologia Experimental e Tecnológica, Portugal
2017/09 - 2018/11 Research Trainee (Research) Instituto de Biologia Experimental e Tecnológica, Portugal
Instituto de Biologia Experimental e Tecnológica, Portugal

Others

Category
Host institution 		Employer
2022/01/01 - Current PhD Student Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
Instituto de Biologia Experimental e Tecnológica, Portugal
Projects

Contract

Designation Funders
2018/01 - Current Chicory as a multipurpose crop for dietary fibre and medicinal terpenes (CHIC)
760891
Research Fellow
European Commission
Ongoing
2019/03 - 2019/09 Desenvolvimento de produtos e ingredientes alimentares bioativos através de recursos agrícolas endógenos portugueses para uma alimentação saudável (NATURE BIOACTIVE FOODS)
PDR2020-101-031527
Research Fellow
Fundação para a Ciência e a Tecnologia, Portugal
Concluded
2017/09 - 2018/11 Functionalized nanostructured delivery systems for food applications: strategies to maximize bioactive compounds’ bioavailability and their safety evaluation (NanoMaxiSafe)
FCT PTCD/AGR_TEC/5215/2014
Estagiário de Investigação
Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Conference abstract
  1. Baixinho, João; Gonçalves, R. F. S.; Guerreiro, J. N.; Gonçalves, V. S. S.; Pinheiro, A. C.; Sarmento, B.; Matias, A. A.. "Development of curcumin solid lipid formulations using a green process technology for food applications: transport and safety evaluation on a mucus-secreting intestinal epithelial cell model". Paper presented in V Prosciba, Iberoamerican conference on supercritical fluids, Campinas, 2019.
    Published
Conference poster
  1. Baixinho, João; M. Cardeira; A. Bento-Silva; A. M. Carvalho Partidário; T. Serra; M. R. Bronze; N. Fernández. "Rice bran oil extracted with Supercritical CO2 and bioactivity evaluation.". Paper presented in Euro Fed Lipid Congress and Expo, 2023.
  2. Baixinho, João; Frédéric B. Gaspar; Paulo J. Amorim Madeira; Maria do Rosário Bronze; Fernández, Naiara. "Winery waste streams as potential natural pesticides". Paper presented in 14th International Chemical and Biological Engineering Conference, 2023.
  3. Ana M. Rodrigues; Baixinho, João; António Ferreira; Teresa Serra; Naiara Fernandez; Maria Rosário Bronze. "TRACE-RICE: Chemical characterization of rice varieties and valorization of rice by-products.". Paper presented in New advances from PRIMA projects for improving Mediterranean Agro-Food value chains, 2023.
  4. Baixinho, João; Melanie S. Matos; Agostinho Alexandre; Fernández, Naiara; C. Nunes dos Santos; Ana A. Matias. "Supercritical CO2 extraction as a tool to isolate potential medicinal sesquiterpenes from Cichorium intybus L. taproots by-products". Paper presented in I Bio.Natural, Bioactive Natural Products Research Meeting, 2019.
  5. J. N. Guerreiro; Baixinho, João; Gonçalves, R. F. S; Gonçalves, V. S. S.; Pinheiro, A. C; Matias, A. A.. "Improving bioactives intestinal absorption using lipidic nanodelivery systems in food applications: evaluation of toxicity and bioavailability". Paper presented in 1st UNGAP Meeting, European Network on Understanding Gastrointestinal Absorption-related Processes, 2018.
  6. Baixinho, João; Guerreiro, J. N; Gonçalves, R. F. S; Gonçalves, V. S. S.; Pinheiro, A. C; Matias, A. A.. "Cytotoxicity and bioavailability evaluation using an in vitro triple co-culture intestinal cell culture: improving bioactives absorption using novel lipidic nanodelivery systems in food applications". Paper presented in BioBarriers, 2018.
Journal article
  1. Cankar, Katarina; Hakkert, Johanna Christina; Sevenier, Robert; Papastolopoulou, Christina; Schipper, Bert; Baixinho, João; Fernández, Naiara; et al. "Lactucin Synthase Inactivation Boosts the Accumulation of Anti-inflammatory 8-Deoxylactucin and Its Derivatives in Chicory (Cichorium intybus L.)". Journal of Agricultural and Food Chemistry (2023): http://dx.doi.org/10.1021/acs.jafc.2c08959.
    10.1021/acs.jafc.2c08959
  2. Débora Cerdá-Bernad; João P. Baixinho; Naiara Fernández; María José Frutos. "Evaluation of Microwave-Assisted Extraction as a Potential Green Technology for the Isolation of Bioactive Compounds from Saffron (Crocus sativus L.) Floral By-Products". Foods 11 15 (2022): 2335-2335. https://doi.org/10.3390/foods11152335.
    10.3390/foods11152335
  3. Ávila-Gálvez, María Ángeles; Rafael-Pita, Carlos; Fernández, Naiara; Baixinho, João; Anastácio, José D.; Cankar, Katarina; Bosch, Dirk; Nunes dos Santos, Cláudia. "Targeting proteases involved in the viral replication of SARS-CoV-2 by sesquiterpene lactones from chicory (Cichorium intybus L.)". Food & Function 13 17 (2022): 8977-8988. http://dx.doi.org/10.1039/d2fo00933a.
    10.1039/d2fo00933a
  4. Rita Valério; Ana Teresa Serra; João Baixinho; Martim Cardeira; Naiara Fernández; Maria Rosário Bronze; Luís C. Duarte; et al. "Combined hydrothermal pre-treatment and enzymatic hydrolysis of corn fibre: Production of ferulic acid extracts and assessment of their antioxidant and antiproliferative properties". Industrial Crops and Products 170 (2021): 113731-113731. https://doi.org/10.1016/j.indcrop.2021.113731.
    10.1016/j.indcrop.2021.113731
  5. Häkkinen, Suvi T.; Sokovic, Marina; Nohynek, Liisa; Ciric, Ana; Ivanov, Marija; Stojkovic, Dejan; Tsitko, Irina; et al. "Chicory Extracts and Sesquiterpene Lactones Show Potent Activity against Bacterial and Fungal Pathogens". Pharmaceuticals 14 9 (2021): 941. http://dx.doi.org/10.3390/ph14090941.
    Open access • Published • 10.3390/ph14090941
  6. João P. Baixinho; José D. Anastácio; Viktoriya Ivasiv; Katarina Cankar; Dirk Bosch; Regina Menezes; Matthew de Roode; et al. "Supercritical CO2 Extraction as a Tool to Isolate Anti-Inflammatory Sesquiterpene Lactones from Cichorium intybus L. Roots". Molecules 26 9 (2021): 2583-2583. https://doi.org/10.3390/molecules26092583.
    10.3390/molecules26092583
  7. GONÇALVES, Raquel F.S.; MARTINS, Joana T.; ABRUNHOSA, Luís; BAIXINHO, João; MATIAS, Ana A.; VICENTE, António A.; PINHEIRO, Ana C.. "Lipid-based nanostructures as a strategy to enhance curcumin bioaccessibility: behavior under digestion and cytotoxicity assessment". Food Research International (2021): 110278. http://dx.doi.org/10.1016/j.foodres.2021.110278.
    Published • 10.1016/j.foodres.2021.110278
Thesis / Dissertation
  1. Baixinho, João Paulo Caseiro. "Development of curcumin lipid formulations for food applications: transport, permeability and safety evaluation on a mucus-secreting intestinal epithelial cell model". Master, 2018. http://hdl.handle.net/10362/52151.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2023/10/05 Investigação cientifica e desenvolvimento dos territórios XI Feira do azeite e do figo
(Macedo de Cavaleiros, Portugal)
2023/05/21 High pressure as a tool to valorize food waste streams. 19th European Meeting on Supercritical Fluids
(Budapest, Hungary)
2022/03/30 Cromatografia como metodologia para caracterizar a composição de extratos bioativos de Codium tomentosum Stackhouse The Macroalgae Biotechnology, Food and Health
REQUIMTE/LAQV (Portugal)
2022/02/28 Supercritical CO2 extraction as a tool to isolate phytochemicals from Rice (Oryza sativa L.) by-products. 2nd Encontro Ibérico de Fluidos Supercríticos
(Coimbra, Portugal)
2019/04 Supercritical CO2 extraction as a tool to isolate medicinal sesquiterpenes from chicory taproots by-products 17th European Meeting on Supercritical Fluids (EMSF 2019) - 7th European Meeting on High Pressure Technology
Universidad de Castilla~La Mancha (Ciudad Real, Spain)
2019 Development of curcumin solid lipid formulations using a green process technology for food applications: transport and safety evaluation on a mucus-secreting intestinal epithelial cell model V Prosciba, Iberoamerican conference on supercritical fluids
Universidade Estadual de Campinas (Campinas, Brazil)

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2022/02/28 - 2022/03/02 Phase equilibrium in supercritical fluids - extraction and formulation
2019/04 - 2019/04 Basic principles of supercritical fluids and actual trends on high pressure (Graduado) Universidad de Castilla-La Mancha, Spain
Distinctions

Award

2019 Best Poster Award - I Bio.Natural Meeting
Universidade Lusófona, Portugal