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Helena Tomás graduated in Chemical Engineering/Biotechnology (IST, Lisbon, Portugal) and has a Ph.D. degree in Technological Chemistry/Biomaterials (1996, University of Lisbon, Portugal). Currently, she is an Associate Professor at the University of Madeira (Portugal) and Senior Researcher in the Materials Research Group at CQM-Centro de Química da Madeira. At UMa, among other responsibilities, she was Head of the Chemistry Department for several periods (2000-2003, 2019-2021, 2022-2025), President of the Pedagogical Board (1999-2001), and Director of the master program in Applied Biochemistry (2010-2019). Her teaching activity has been mainly focused on the Biochemistry and Biomaterials areas. Her research work stands out for its multidisciplinary approach, combining chemistry, materials science, and biotechnology to create impactful solutions with potential applications in regenerative medicine, and cancer (namely, targeted nanomaterials for cancer therapy). She has been mainly devoted to the development of nanogels and dendrimer-based and clay-based nanomaterials (drug/gene delivery and theranostics). She was principal investigator/participant in several research projects funded by FCT, INTERREG MAC, INTERREG Atlantic Area, ProCiência 2020, Horizon Europe, as well as Chinese institutions. At CQM, she was the main supervisor of 5 post-doc researchers, 5 PhD students (2 still ongoing), and 10 master students (she also co-supervised 4 post-doc researchers, 7 PhD students, and 12 master students). She belonged to the management committee of the COST action TD0802: Dendrimers in Biomedical Applications (2010-2013), as well as the COST action CA17140: NANO2CLINIC-Cancer nanomedicine - from the bench to the bedside (2018-2023, where she was a member of the proponent group). She authored/co-authored 85 papers in peer-reviewed journals, and 4 book chapters (WoS h-index= 39, total citations> 5700). She has 21 publications with more than 80 citations and one of her publications was cited > 1100 times. She was part of the Stanford University and Elsevier Worlds Top 2% Scientists list in 2022 and 2023. Throughout her entire career, she has consistently devoted a considerable amount of her time to promoting science among both younger audiences and the general public. In this regard, it is noteworthy to mention: a) She was a member of the National Commission for the celebration of the Year of the Periodic Table (2019) and promoted/organized various activities on the topic throughout the island of Madeira. b) She was responsible for organizing the event «A QUÍMICA É DIVERTIDA» («Chemistry in Fun», a regular science dissemination event involving fun experiments, colloquia, competitions, etc.) at CQM/UMa (2006-2019). c) She organized the participation of CQM in the nationwide initiative promoted by the «Ciência Viva» agency, offering research internships for high school students during the summer (2007-2019). d) She organized, in 2007, the CQM participation in a set of 3 television science programs for «Panda Channel» which is a TV channel dedicated to children. e) She was responsible (partner leader) for Madeira's participation in the European project Future2020: How will life be in 2020? Call: FP7-PEOPLE-2013-NIGHT, project 609809 (European Researchers' Night 2013). During this event, among other activities, she organized a TV debate with Madeira local TV (RTP Madeira). f) She presented numerous science lessons in secondary schools on the island of Madeira.
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Identification

Personal identification

Full name
Helena Maria Pires Gaspar Tomás

Citation names

  • Tomás, Helena
  • Tomás, H.
  • H. Tomás

Author identifiers

Ciência ID
4D14-D31E-A8BE
ORCID iD
0000-0002-7856-2041
Google Scholar ID
https://scholar.google.com.br/citations?user=gMkTUB8AAAAJ&hl=pt-BR
Researcher Id
E-5991-2010
Scopus Author Id
6508104177

Email addresses

  • lenat@staff.uma.pt (Professional)
  • lenat@uma.pt (Professional)

Addresses

  • Universidade da Madeira. CQM-Centro de Química da Madeira, Faculdade de Ciências Exactas e Engenharia, Universidade da Madeira, Campus da Penteada, 9020-105, Funchal, S. Pedro, Portugal (Professional)

Websites

Knowledge fields

  • Engineering and Technology - Nano-technology - Nano-materials
  • Medical and Health Sciences - Medical Biotechnology - Technologies Involving the Manipulation of Cells, Tissues, Organs or the Whole Organism
  • Medical and Health Sciences - Medical Biotechnology - Biomaterials

Languages

Language Speaking Reading Writing Listening Peer-review
English Upper intermediate (B2) Advanced (C1) Advanced (C1) Advanced (C1)
French Upper intermediate (B2) Intermediate (B1) Intermediate (B1) Advanced (C1)
Portuguese (Mother tongue)
Education
Degree Classification
1996
Concluded
 TECHNOLOGICAL CHEMISTRY - BIOMATERIALS (Doutoramento)
Universidade de Lisboa Faculdade de Ciências, Portugal
"Avaliação do comportamento à corrosão e da citocompatibilidade de uma liga ortopédica de Co-Cr-Mo" (THESIS/DISSERTATION)
 Aproved with distinction
1989
Concluded
 CHEMICAL ENGINEERING - BIOTECHNOLOGY (Licenciatura)
Universidade de Lisboa Instituto Superior Técnico, Portugal
"n/a" (THESIS/DISSERTATION)
 15
Affiliation

Science

Category
Host institution 		Employer
2004/01/01 - Current Principal Investigator (Research) Universidade da Madeira Centro de Química da Madeira, Portugal
Universidade da Madeira Centro de Química da Madeira, Portugal

Teaching in Higher Education

Category
Host institution 		Employer
2002/02/22 - Current Associate Professor (University Teacher) Universidade da Madeira, Portugal
1996/05/28 - 2002/02/03 Assistant Professor (University Teacher) Universidade da Madeira, Portugal
1995/10/13 - 1996/05/27 Trainee Assistant (University Teacher) Universidade da Madeira, Portugal

Positions / Appointments

Category
Host institution 		Employer
2022/12/21 - 2025/04/10 Coordinator of the Chemistry Department Universidade da Madeira, Portugal
Universidade da Madeira, Portugal
2019/02/08 - 2021/03/10 Coordinator of the Chemistry Department Universidade da Madeira, Portugal
2009/04/01 - 2021/01/30 Diretor of the Materials Research Group at CQM Universidade da Madeira Centro de Química da Madeira, Portugal
2017/06/27 - 2019/10/17 Head of the Pedagogic Council of the Faculty of Exact Sciences and Engineering Universidade da Madeira, Portugal
2010/04/15 - 2019/10/17 Director of the Master in Applied Biochemistry Universidade da Madeira, Portugal
2000/07/04 - 2003/11/19 Coordinator of the Chemistry Department Universidade da Madeira, Portugal
1999/03/03 - 2001/03/21 President of the Pedagogic Council Universidade da Madeira, Portugal

Others

Category
Host institution 		Employer
1990/10/01 - 1995/09/30 Ph.D. student (Ph.D. grant from JNICT) Universidade de Lisboa Faculdade de Ciências, Portugal
Projects

Contract

Designation Funders
2025/09/01 - Current FOCUS-4R - Fostering Outermost regions Capabilities in Research and Innovation and Upgrading Skills complying with 4R principles
101217074
Researcher
European Commission
Ongoing
2020 - 2023 Inv2Mac- Potencial aprovechamiento de biomasa generada a partir de especies vegetales invasoras de la Macaronesia para uso industrial
MAC2/4.6d/229
Researcher
European Regional Development Fund
2020 - 2023 Construction of Functional Dendrimer-Based Nanogels For Ultrasound-Enhanced Tumor Theranostics
-
Researcher
Science and Technology Commission of Shanghai Municipality
2018/01/01 - 2021/06/30 BLUEHUMAN (partner leader) - BLUE biotechnology as a road for innovation on HUMAN's health aiming smart growth in Atlantic Area
EAPA 151/2016
Researcher
European Regional Development Fund
Concluded
2016/07/01 - 2020/03/31 BaiTS - Biodegradable dendrimers for Targeted neuroprotective therapies in Stroke
PTDC/CTM-NAN/3547/2014
Researcher
Universidade da Madeira, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2017 - 2019 MARINEBLUEREFINE-Valorização do potencial insular para aplicações de valor acrescentado
M1420-01-0247-FEDER-000006
Researcher
European Regional Development Fund
Concluded
2017 - 2019 ECOFIBRAS - Valorización ecosostenible de especies vegetales invasoras de la Macaronesia para la obtención de fibras de uso industrial
MAC/4.6d/040
Researcher
European Regional Development Fund
2013/04/03 - 2015/08/02 DENDIMAGE - Development of Novel Dendrimer-Based Nanoparticles for Dual Mode Computed Tomography and Magnetic Resonance Imaging of Tumors
PTDC/CTM-NAN/1748/2012
Researcher
Universidade da Madeira, Portugal

Universidade da Madeira Centro de Química da Madeira, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2012/03/01 - 2015/02/28 Self-assembled nanoparticles based on PEG-PLA-dendrimer building blocks for dual gene/drug delivery
PTDC/CTM-NAN/116788/2010
Researcher
Universidade da Madeira, Portugal

Universidade da Madeira Centro de Química da Madeira, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2011/04/01 - 2014/09/30 DENDRIMAT - New materials for drug/gene delivery based on the self-assembly of dendrimer-chitosan-single stranded DNA
PTDC/CTM-NAN/112428/2009
Principal investigator
Universidade da Madeira, Portugal

Universidade da Madeira Centro de Química da Madeira, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2012 - 2014 Dendrimer-based multifunctional hybrid nanoparticles as probes for dual-mode targeted tumor diagnosis
12520705500
Researcher
Science and Technology Commission of Shanghai Municipality
Concluded
2009 - 2013 VinSaudeMAC – Evaluation of the biological effects of red wines on the prevention of atherosclerotic, oncologic and neurologic diseases
MAC/1/M105
Researcher
European Regional Development Fund
2011 - 2012 Assembly of carbon nanotubes onto the surface of electrospun nanofibers for stem cell differentiation applications
11BA1400500
Researcher
Foundation - Shanghai Baiyulan Foundation
2007/09/01 - 2010/12/31 DENDRALGENE - Design of new gene delivery vectors based on dendrimers, alginate and the RGD sequence for bone tissue engineering
PTDC/SAU-BEB/71161/2006
Principal investigator
Universidade da Madeira, Portugal

Universidade da Madeira Centro de Química da Madeira, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2001/01/01 - 2005/12/31 Three-dimensional systems of collagen type I, proteoglycans and growth factors for bone cell proliferation and differentiation
POCTI/ESP/33620/99
Principal investigator
Universidade da Madeira Centro de Química da Madeira, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Book chapter
  1. Tomás, Helena; Rodrigues, João. Corresponding author: Rodrigues, João. "Dendrimers and dendrimer-based nano-objects for oncology applications". In New Trends in Smart Nanostructured Biomaterials in Health Sciences, 41-78. Elsevier, 2023.
    Published • 10.1016/b978-0-323-85671-3.00002-6
  2. Tomás, H.; A. P. Pêgo; R. Castro; P. Moreno. "Nucleic acid delivery mediated by polysaccharide-based vectors". edited by M.H. Gil. Research Signpost/Transworld Research Network, 2014.
    Published
  3. TOMAS, H; FREIRE, AP; ABRANTES, LM; KOSSOWSKY, R; KOSSOVSKY, N. "Activity of plasma proteins regarding biomaterials corrosion - pH Effects". 1995.
Conference abstract
  1. Mendes, Fátima; del Olmo, Natalia Sanz; Garcia, Jorge San Jacinto; Malkoch, Michael; Tomás, Helena. "Polyester-based dendritic block copolymers with biodegradable properties for potential cancer treatment". Paper presented in 10th CQM Meeting, Funchal, 2023.
    Published
  2. Mendes, Fátima; del Olmo, Natalia Sanz; Garcia, Jorge San Jacinto; Malkoch, Michael; Tomás, Helena. "Synthesis of Cisplatin loaded Polyester-based dendritic structures for the targeted treatment of Osteosarcoma". Paper presented in 2nd CA17140 STSM Conference, 2023.
    Published
  3. Duarte, Ana; Tomás, Helena; Rodrigues, João. Corresponding author: Rodrigues, João. "Development of Laponite® gels for cisplatin delivery". Paper presented in 10th CQM Annual Meeting, Funchal, 2023.
  4. dos Orfaos, Lydia; Rodrigues, João; Tomás, Helena. "Oxidation of fluorinated PAMAM dendrimer - A combination of fluorescence and NMR traceability". Paper presented in 9th CQM Annual Meeting, Funchal, 2022.
    Published
  5. Duarte, Ana; Olim, Filipe; Tomás, Helena. Corresponding author: Olim, Filipe. "Fucoidan-based delivery system for cisplatin in glioblastoma cells". Paper presented in 9th CQM Annual Meeting, Funchal, 2022.
  6. Mendes, Fátima; Olim, Filipe; Neves, Ana Rute; Rodrigues, João; Tomás, Helena. "Bisphosphonates: a brief review and envisaged work towards osteosarcoma treatment". Paper presented in 8th CQM annual meeting, Funchal, 2021.
    Published
  7. Martins, Ivo; Pita, Filipa; Tomás, Helena; Rodrigues, João. Corresponding author: Martins, Ivo. "Exploring new routes in the preparation of carbon dots for biomedical applications". Paper presented in 8th CQM Annual Meeting, Funchal, 2021.
  8. dos Orfaos, Lydia; Tomás, Helena; Rodrigues, João. "A fluorinated dendrimer for traceable gene delivery". Paper presented in 8th CQM Annual Meeting, Funchal, 2021.
    Published
  9. Martins, Ivo J; Tomás, Helena; Lahoz, Fernando; Rodrigues, João. "Nanohybrids and Hybridplexes based on Carbon Dots and PAMAM Dendrimer for Bioimaging and Gene Delivery". Paper presented in Encontro Nacional da Sociedade Portuguesa de Química, Braga, 2021.
  10. Maciel, D.; Nunes, N. ; Tomás, H.; Rodrigues, J.. Corresponding author: Rodrigues, J.. "Ruthenium Metallodendrimers for Cancer Therapy: Contributions to the Field and Perspectives (Invited lecture)". Paper presented in Sino-French Innovative Nanomedicine Forum & Celebration of 80th Birthday of Professor Jean-Pierre Majoral, Shanghai, 2021.
  11. Mendes, Fátima; Olim, Filipe; Neves, Ana Rute; Vieira, Mariana; Rodrigues, João; Tomás, Helena. "Laponite®-based nanogels for bone tissue regeneration and treatment of osteoporosis". Paper presented in 7th CQM Annual Meeting, Funchal, 2020.
    Published
  12. dos Orfaos, Lydia; Tomás, Helena; Rodrigues, João. "The fluorination of poly(amidoamine) (PAMAMG4-NH2) dendrimers - synthesis characterization and biological studies". Paper presented in 7th CQM Annual Meeting, Funchal, 2020.
  13. Alves, Carla S.; Castillo, Mariangie; Pereira, Bruna; Tomás, Helena; Rodrigues, João Manuel Cunha. "A Ciência e a sua Divulgação - Projecto BtG by CQM". Paper presented in XV Colóquio CIE-UMa: LITERACIA CIENTÍFICA- Ensino, Aprendizagem e Quotidiano, Funchal, 2020.
    Published
  14. Mendes, Fátima; Olim, Filipe; Neves, Ana Rute; Rodrigues, João; Tomás, Helena. "Laponite®-based nanogels for Bone Tissue Regeneration.". Paper presented in 6th CQM Meeting, Porto Moniz, 2019.
    Published
  15. dos Orfaos, Lydia; Rodrigues, João; Tomás, Helena. "Fluorescent dendrimers - The fluorination approach". Paper presented in 6th CQM Annual Meeting, Porto Moniz, 2019.
  16. Neves, Ana Rute; Olim, Filipe; Luís, Andreia; Mendes, Fátima; Rodrigues, João; Tomás, Helena. "Marine-based nanomaterials for tissue engineering.". Paper presented in MAD-NANO18: Madeira International Conference on Emerging Trends and Future of Nanomaterials for Human Health, Funchal, 2018.
    Published
  17. Xiong, Zhijuan; Alves, Carla S.; Li, Aijun; Chen, Feng; Liu, Jinyuan; Shen, Mingwu; Tomas, Helena; Shi, Xiangyang. "A gene delivery approach using zwitterion-modified dendrimer-entrapped gold nanoparticles for inhibition of cancer cell metastasis". 2018.
  18. Xiao, Shili; Rodrigues, Joao; Tomas, Helena. "Laponite-based nanohybrids for enhanced solubility of dexamethasone and osteogenic differentiation of human mesenchymal stem cells". 2017.
    10.1016/j.jconrel.2017.03.250
  19. Zhan, Yuan; Goncalves, Mara; Yi, Panpan; Capelo, Debora; Zhang, Yuhong; Rodrigues, Joao; Liu, Changsheng; et al. "Thermo/Redox/pH-stimulative nanogel delivery systems". 2016.
    10.1016/j.nano.2015.12.337
  20. Kong, Lingdan; Hou, Wenxiu; Tomas, Helena; Shi, Xiangyang. "RGD peptide-modified dendrimer-entrapped goldnanoparticles enable effective gene delivery to stem cells". 2014.
  21. Li, Y.; Santos, J.L.; Maciel, D.; Tomás, H.; Rodrigues, J.; Li Y; Santos JL; et al. "Injectable hybrid laponite/alginate hydrogels for sustained release of methylene blue.". 2011.
    10.1016/j.jconrel.2011.08.119
  22. Sargo, S.; Santos, J. L.; Rodrigues, J.; Pego, A. P.; Granja, P. L.; Tomas, H.. "New Pamam dendrimers/alginate nanoparticles for gene delivery". 2008.
  23. Santos, J. L.; Rodrigues, J.; Pego, A. P.; Granja, P. L.; Tomas, H.. "Novel conjugates of dendrimers and fatty acids for gene delivery applications". 2008.
  24. Santos, J.; Oramas, E.; Pêgo, A.; Granja, P.; Tomás, H.. "In vitro osteoblastic differentiation of MSCs using PAMAM dendrimers as delivery vectors for the hBMP-2 gene". 2008.
Conference poster
  1. Mendes, Fátima; del Olmo, Natalia Sanz; Garcia, Jorge San Jacinto; Malkoch, Michael; Tomás, Helena. "Development of polyester-based dendritic structures loaded with cisplatin for targeted treatment of osteosarcoma". Paper presented in Molecules4Life - I International Meeting 2023, 2023.
  2. dos Orfaos, Lydia; Tomás, Helena; Rodrigues, João. "Fluorination of G4 PAMAM dendrimers for gene delivery". Paper presented in 31st Conference of the European Society for Biomaterials - ESB2021, 2021.
  3. Gonçalves, Mara; João Manuel Cunha Rodrigues; Li, Yulin; Tomás, Helena. "Amine partially functionalized polyester dendrimers for doxorubicin delivery". Paper presented in FIRST COST ACTION CA17140 Conference, 2019.
  4. Mendes, Fátima; Olim, Filipe; Neves, Ana Rute; Rodrigues, João; Tomás, Helena. "Laponite®-based nanogels for the treatment of osteoporosis.". Paper presented in XXVI Encontro Nacional da SPQ ¿ XXVIENSPQ., 2019.
  5. dos Orfaos, Lydia; Rodrigues, João; Tomás, Helena. "Functionalization of generation four PAMAM dendrimers - the fluorination effect". Paper presented in XXVI Encontro Nacional da Sociedade Portuguesa de Química, 2019.
  6. dos Orfaos, Lydia; Camacho, Cláudia; Tomás, Helena; Rodrigues, João. "Fluorinated and Non-fluorinated Generation Four (G4) PAMAM dendrimers". Paper presented in 11th International Dendrimer Symposium, 2019.
  7. Alves, Carla S.; Antunes, Natacha; Tomás, Helena; Castanho, Miguel A.R.B.; Rodrigues, João Manuel Cunha. "Synthesis of Novel Surface Modified Dendrimers for Dengue and Zika Viral Entry Inhibition". Paper presented in 11th International Dendrimer Symposium, 2019.
  8. Abreu, Nilsa; Alves, Carla S.; Tomás, Helena; Shi, Xiangyang; Rodrigues, João Manuel Cunha. "Hyaluronic Acid-Modified Dendrimer Entrapped Gold Nanoparticles". Paper presented in 11th International Dendrimer Symposium, 2019.
  9. Santos, SD; Xavier, Miguel; Leite DM; Moreira, Débora; Custódio, Beatriz; Torrado M; Castro, R.; et al. "The transport of therapeutic molecules to the ischemic brain: dendrimers as carriers in pre-clinical studies". Paper presented in XVI Meeting of the Portuguese Society for Neuroscience, 2019.
  10. Gonçalves, Mara; João Manuel Cunha Rodrigues; Tomás, Helena. "Polyester dendrimers as delivery vehicles for doxorubicin". Paper presented in Madeira International Conference on Emerging Trends and Future of Nanomaterials for Human Health - MAD-NANO18, 2018.
  11. Mendes, Fátima; Olim, Filipe; Neves, Ana Rute; Rodrigues, João; Tomás, Helena. "Laponite-based Nanogels for Alendronate Delivery". Paper presented in MAD-NANO18: Madeira International Conference on Emerging Trends and Future of Nanomaterials for Human Health., 2018.
  12. Santos, SD; Xavier, Miguel; Leite, DM; Moreira, Débora; Custódio, Beatriz; Torrado M; Castro, R; et al. "Blood-Brain Barrier Transport and Neuronal Uptake of PAMAM Dendrimers after Focal Brain Ischemia". Paper presented in i3S annual meeting, 2018.
  13. Santos, SD; Xavier, Miguel; Leite DM; Moreira, Débora; Castro, R; Leiro, Victoria; Rodrigues, J.; Tomás, Helena; Pêgo, Ana. "Nanoparticle-mediated Blood-Brain Barrier Transport for Neuronal Delivery in Focal Brain Ischemia". Paper presented in 10th International Symposium on Neuroprotection and Neurorepair, 2018.
  14. Ideia, P.; Pinto, J.; Ferreira, R.; Figueiredo, L.; Tomás, H.; Castilho, P. C.. "Extraction and characterization of hydroxyapatite from Madeira Island fish transforming industry by-products.". Paper presented in 2nd BioMaH conference, 2018.
  15. Gonçalves, Mara; João Manuel Cunha Rodrigues; Tomás, Helena. "Doxorubicin-based systems with improved anti-cancer efficacy". Paper presented in Ciência 2018, 2018.
  16. Gonçalves, Mara; João Manuel Cunha Rodrigues; Tomás, Helena. "Poly(amidoamine) vs bis-MPA Dendrimers: A comparative Study for Doxorubicin Encapsulation". Paper presented in Gordon Research Center on Cancer Nanotechnology, 2017.
  17. Santos, S.D.; Leiro, V; Lopes, C.D.F.; Xavier M.A; Leite, D.; Tomás, H.; Pêgo, A.P.. "PEGylated PAMAM dendrimers can effectively reach the injured ischemic brain". Paper presented in 6th China-Europe Symposium on Biomaterials in Regenerative Medicine CESB2017. Porto, Portugal., 2017.
  18. Santos SD; Leiro, V; Lopes CDF; Xavier MA; Leite, D.; Tomás, H.; Pêgo, AP. "Blood-Brain Barrier Transport and Brain Uptake of Poly(Ethylene Glycol)-Modified PAMAM Dendrimers in brain ischemia". Paper presented in XV Meeting of the Portuguese Society for Neuroscience., Braga, Portugal, 2017.
  19. Gonçalves, Mara; Ana Cristina Dias Olival; João Manuel Cunha Rodrigues; Tomás, Helena. "Polyester Dendrimers for Dual Gene and Drug Delivery - Preliminary Results". Paper presented in Indo-Portuguese Workshop on Emerging Trends of Nanotechnology in Chemistry and Biology ¿ INCB-2016, 2016.
  20. Gonçalves, Mara; Maciel, Dina; Capelo, Débora; Xiao, Shili; Sun, Wenjie; Shi, Xiangyang; João Manuel Cunha Rodrigues; Tomás, Helena; Li, Yulin. "Poly(amidoamine) dendrimer-mediated nanogels for drug delivery and intracellular tracking". Paper presented in 1st International Conference on Emerging Trends of Nanotechnology in Drug Discovery - INDD-2014, 2014.
  21. Gonçalves, Mara; Maciel, Dina; Xiao, Shili; Shi, Xiangyang; João Manuel Cunha Rodrigues; Tomás, Helena. "Dendrimer-Assisted Formation Of Self-Fluorescent Nanogels For Simultaneous Drug Delivery and Intracellular Tracking Imaging". Paper presented in Chinese Medicinal Chemistry Symposium (CMCS), 2013.
  22. Maciel, Dina; Gonçalves, Mara; Alves, C. S.; Shi, Xiangyang; João Manuel Cunha Rodrigues; Tomás, Helena; Li, Yulin. "Triple Cell-Responsive Nanogels For Drug Delivery Into Cancer Cells". Paper presented in Chinese Pharmaceutical Conference, 2013.
  23. Castro, Rita; Santos, J.L.; Gonçalves, Mara; João Manuel Cunha Rodrigues; Tomás, Helena. "Fatty-acid Functionalized PAMAM Dendrimers for Gene Silencing". Paper presented in 8th International Dendrimer Symposium, 2013.
  24. Gonçalves, Mara; Castro, Rita; João Manuel Cunha Rodrigues; Tomás, Helena. "PAMAM Dendrimers do Not Affect Mesenchymal Stem Cells Differentiation". Paper presented in 8th International Dendrimer Symposium, 2013.
  25. Gonçalves, Mara; Castro, Rita; João Manuel Cunha Rodrigues; Tomás, Helena. "Effect of PAMAM Dendrimers with Different Surface Functionalities on Mesenchymal Stem Cells Differentiation". Paper presented in 7th International Meeting of the Portuguese Society for Stem Cells & Cell Therapies, 2012.
  26. Santos JL; Oramas EG; Pêgo, Ana Paula; Granja PL; Tomás, H.. "Osteogenic differentiation of mesenchymal stem cells through gene delivery". Paper presented in 3rd International Meeting of the Portuguese Society for Stem Cells and Cellular Therapy, ¿From Molecular Mechanisms to Therapeutical applications¿, 2008, Faro, Portugal,, 2008.
  27. Santos JL; Oramas EG; Pêgo, Ana Paula; Granja PL; Tomás, H.. "In vitro osteogenesis via gene delivery". Paper presented in 5th Marie Curie Cutting-Edge Conference, 2008,Funchal, Madeira, Portugal, 2008.
  28. Santos JL; Oliveira, H.; Oramas EG; Pêgo, Ana Paula; Granja PL; Tomás, H.. "Gene therapy platform for bone regeneration using dendrimers and osteogenic plasmids systems". Paper presented in Gordon Research Conference-Biomaterials: Biocompatability/Tissue Engineering, 2007, Holderness, NH, USA, 2007.
  29. Santos L.; Pêgo, Ana Paula; Granja PL; Tomás, H.. "In vitro evaluation of gene delivery in bone marrow stromal cells by polyamidoamine dendrimers". Paper presented in XIV Annual Congress of the European Society of Gene Delivery, 2006, Athens, Greece, 2006.
  30. Costa, Maria; Monteiro, E.; Trigo Cabral, A.; Tomás, H.; Fernandes, M.H.. "Three dimensional matrices support the growth of human bone marrow cells.". Paper presented in ESB 2002 ¿ 17th European Conference on Biomaterials, Barcelona, Espanha, 11-14 de Setembro de 2002., 2002.
Journal article
  1. Rita Castro; Pedro L. Granja; João Rodrigues; Ana Paula Pêgo; Helena Tomás. "Bioinspired hybrid DNA/dendrimer-based films with supramolecular chirality". Journal of Materials Chemistry B (2025): https://doi.org/10.1039/D4TB02761B.
    10.1039/D4TB02761B
  2. Waad El Mejri; Ayoub El Mahdi; Fátima Mendes; Rita Castro; Leila Njim; Sonia Zaied; Helena Tomás; et al. "Chitosan films synthesized via thiol-ene click chemistry: Toward safe and versatile platforms for packaging, cosmetics and biomedical applications". Sustainable Chemistry and Pharmacy 40 (2024): 101643. https://doi.org/10.1016/j.scp.2024.101643.
    Open access • 10.1016/j.scp.2024.101643
  3. Ye Tian; Zhiqiang Wang; Xu Xu; Yunqi Guo; Yanni Ma; Yanqi Lu; Mingwu Shen; et al. "Natural alkaloids from Dicranostigma leptopodum (Maxim.) Fedde and their G5. NHAc-PBA dendrimer-alkaloid complexes for targeting chemotherapy in breast cancer MCF-7 cells". Natural Product Research (2024): 1-18. https://doi.org/10.1080/14786419.2024.2335669.
    Open access • 10.1080/14786419.2024.2335669
  4. Jinkai Zhang; Yu Zhuang; Ruilong Sheng; Helena Tomás; João Rodrigues; Guangyin Yuan; Xudong Wang; Kaili Lin. "Smart stimuli-responsive strategies for titanium implant functionalization in bone regeneration and therapeutics". Materials Horizons (2024): http://dx.doi.org/10.1039/d3mh01260c.
    10.1039/d3mh01260c
  5. Jinxia Wang; Zhiqiang Wang; Guixiang Zhang; João Rodrigues; Helena Tomás; Xiangyang Shi; Mingwu Shen. "Blood–brain barrier-crossing dendrimers for glioma theranostics". Biomaterials Science (2024): https://doi.org/10.1039/D4BM00043A.
    10.1039/D4BM00043A
  6. Martins, Ivo J; Tomás, Helena; Rodrigues, João. "Carbon dots and dendrimers nanohybrids: from synthesis to applications". Materials Today Chemistry 32 101662 (2023): https://doi.org/10.1016/j.mtchem.2023.101662.
    Published
  7. Cláudia Camacho; Dina Maciel; Helena Tomás; João Rodrigues. "Biological Effects in Cancer Cells of Mono- and Bidentate Conjugation of Cisplatin on PAMAM Dendrimers: A Comparative Study". Pharmaceutics (2023): https://doi.org/10.3390/pharmaceutics15020689.
    10.3390/pharmaceutics15020689
  8. Zeyu Fu; Yu Zhuang; Jinjie Cui; Ruilong Sheng; Helena Tomás; João Rodrigues; Bin Zhao; Xudong Wang; Kaili Lin. "Development and challenges of cells- and materials-based tooth regeneration". Engineered Regeneration (2022): http://dx.doi.org/10.1016/j.engreg.2022.04.003.
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  68. Li, Y.; Rodrigues, J.; Tomás, H.. "Injectable and biodegradable hydrogels: Gelation, biodegradation and biomedical applications". Chemical Society Reviews 41 6 (2012): 2193-2221. http://www.scopus.com/inward/record.url?eid=2-s2.0-84863229467&partnerID=MN8TOARS.
    10.1039/c1cs15203c
  69. Shan, Y.; Luo, T.; Peng, C.; Sheng, R.; Cao, A.; Cao, X.; Shen, M.; et al. "Gene delivery using dendrimer-entrapped gold nanoparticles as nonviral vectors". Biomaterials 33 10 (2012): 3025-3035. http://www.scopus.com/inward/record.url?eid=2-s2.0-84856275170&partnerID=MN8TOARS.
    10.1016/j.biomaterials.2011.12.045
  70. Santos, J.L.; Nouri, A.; Fernandes, T.; Rodrigues, J.; Tomás, H.. "Gene delivery using biodegradable polyelectrolyte microcapsules prepared through the layer-by-layer technique". Biotechnology Progress 28 4 (2012): 1088-1094. http://www.scopus.com/inward/record.url?eid=2-s2.0-84864859566&partnerID=MN8TOARS.
    10.1002/btpr.1576
  71. Nouri, A.; Castro, R.; Santos, J.L.; Fernandes, C.; Rodrigues, J.; Tomás, H.. "Calcium phosphate-mediated gene delivery using simulated body fluid (SBF)". International Journal of Pharmaceutics 434 1-2 (2012): 199-208. http://www.scopus.com/inward/record.url?eid=2-s2.0-84864153035&partnerID=MN8TOARS.
    10.1016/j.ijpharm.2012.05.066
  72. Goncalves, M.; Castro, R.; Rodrigues, J.; Tomas, H.; Gonçalves, M.; Tomás, H.. "The Effect of PAMAM Dendrimers on Mesenchymal Stem Cell Viability and Differentiation". Current Medicinal Chemistry 19 29 (2012): 4969-4975. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000309976900008&KeyUID=WOS:000309976900008.
    10.2174/0929867311209024969
  73. Rodrigues, J.; Jardim, M.G.; Figueira, J.; Gouveia, M.; Tomás, H.; Rissanen, K.. "Poly(alkylidenamines) dendrimers as scaffolds for the preparation of low-generation ruthenium based metallodendrimers". New Journal of Chemistry 35 10 (2011): 1938-1943. http://www.scopus.com/inward/record.url?eid=2-s2.0-80053361429&partnerID=MN8TOARS.
    10.1039/c1nj20364a
  74. Pandita, D.; Santos, J.L.; Rodrigues, J.; Pêgo, A.P.; Granja, P.L.; Tomás, H.. "Gene delivery into mesenchymal stem cells: A biomimetic approach using rgd nanoclusters based on poly(amidoamine) dendrimers". Biomacromolecules 12 2 (2011): 472-481. http://www.scopus.com/inward/record.url?eid=2-s2.0-79951658350&partnerID=MN8TOARS.
    10.1021/bm1012647
  75. Santos, J.L.; Pandita, D.; Rodrigues, J.; Pêgo, A.P.; Granja, P.L.; Tomás, H.. "Non-viral gene delivery to mesenchymal stem cells: Methods, strategies and application in bone tissue engineering and regeneration". Current Gene Therapy 11 1 (2011): 46-57. http://www.scopus.com/inward/record.url?eid=2-s2.0-79951686783&partnerID=MN8TOARS.
    10.2174/156652311794520102
  76. Li, Y.; MacIel, D.; Tomás, H.; Rodrigues, J.; Ma, H.; Shi, X.. "PH sensitive Laponite/alginate hybrid hydrogels: Swelling behaviour and release mechanism". Soft Matter 7 13 (2011): 6231-6238. http://www.scopus.com/inward/record.url?eid=2-s2.0-79959495125&partnerID=MN8TOARS.
    10.1039/c1sm05345k
  77. Santos, J.L.; Oliveira, H.; Pandita, D.; Rodrigues, J.; Pêgo, A.P.; Granja, P.L.; Tomás, H.. "Functionalization of poly(amidoamine) dendrimers with hydrophobic chains for improved gene delivery in mesenchymal stem cells". Journal of Controlled Release 144 1 (2010): 55-64. http://www.scopus.com/inward/record.url?eid=2-s2.0-77953239685&partnerID=MN8TOARS.
    10.1016/j.jconrel.2010.01.034
  78. Santos, J.L.; Pandita, D.; Rodrigues, J.; Pêgo, A.P.; Granja, P.L.; Balian, G.; Tomás, H.. "Receptor-mediated gene delivery using PAMAM dendrimers conjugated with peptides recognized by mesenchymal stem cells". Molecular Pharmaceutics 7 3 (2010): 763-774. http://www.scopus.com/inward/record.url?eid=2-s2.0-77953253240&partnerID=MN8TOARS.
    10.1021/mp9002877
  79. Santos, J.L.; Oramas, E.; Pêgo, A.P.; Granja, P.L.; Tomás, H.. "Osteogenic differentiation of mesenchymal stem cells using PAMAM dendrimers as gene delivery vectors". Journal of Controlled Release 134 2 (2009): 141-148. http://www.scopus.com/inward/record.url?eid=2-s2.0-60649096454&partnerID=MN8TOARS.
    10.1016/j.jconrel.2008.11.007
  80. Alves, N.M.; Shi, J.; Oramas, E.; Santos, J.L.; Tomás, H.; Mano, J.F.. "Bioinspired superhydrophobic poly(L-lactic acid) surfaces control bone marrow derived cells adhesion and proliferation". Journal of Biomedical Materials Research - Part A 91 2 (2009): 480-488. http://www.scopus.com/inward/record.url?eid=2-s2.0-70349464694&partnerID=MN8TOARS.
    10.1002/jbm.a.32210
  81. Fernandes, L.F.; Costa, M.A.; Fernandes, M.H.; Tomás, H.. "Osteoblastic behavior of human bone marrow cells cultured over adsorbed collagen layer, over surface of collagen gels, and inside collagen gels". Connective Tissue Research 50 5 (2009): 336-346. http://www.scopus.com/inward/record.url?eid=2-s2.0-70350754598&partnerID=MN8TOARS.
    10.3109/03008200902855909
  82. Nascimento, M.L.; Mueller, W.D.; Carvalho, A.C.; Tomás, H.M.; Mueller, W.-D.; Tomás, H.. "Electrochemical characterization of titanium biomaterials using the Mini-cell System". Journal of Materials Science 41 11 (2006): 3323-3327. http://www.scopus.com/inward/record.url?eid=2-s2.0-33745697952&partnerID=MN8TOARS.
    10.1007/s10853-005-5426-6
  83. Sedláková, P.; Svobodová, J.; Mikšík, I.; Tomás, H.. "Separation of poly(amidoamine) (PAMAM) dendrimer generations by dynamic coating capillary electrophoresis". Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 841 1-2 (2006): 135-139. http://www.scopus.com/inward/record.url?eid=2-s2.0-33747788046&partnerID=MN8TOARS.
    10.1016/j.jchromb.2006.03.013
  84. Caldeira Araújo, H.; Smit, W.; Verhoeven, N.M.; Salomons, G.S.; Silva, S.; Vasconcelos, R.; Tomás, H.; et al. "Guanidinoacetate methyltransferase deficiency identified in adults and a child with mental retardation". American Journal of Medical Genetics 133 A 2 (2005): 122-127. http://www.scopus.com/inward/record.url?eid=2-s2.0-20044386883&partnerID=MN8TOARS.
    10.1002/ajmg.a.30226
  85. TOMAS, H; CARVALHO, GS; FERNANDES, MH; FREIRE, AP; ABRANTES, LM; Tomás, H.. "The use of rat, rabbit or human bone marrow derived cells for cytocompatibility evaluation of metallic elements". Journal of Materials Science-Materials in Medicine 8 4 (1997): 233-238. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:A1997WU94500008&KeyUID=WOS:A1997WU94500008.
    10.1023/A:1018543808210
  86. Tomás, H.; Carvalho, G.S.; Fernandes, M.H.; Freire, A.P.; Abrantes, L.M.. "Effects of Co-Cr corrosion products and corresponding separate metal ions on human osteoblast-like cell cultures". Journal of Materials Science: Materials in Medicine 7 5 (1996): 291-296. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030150670&partnerID=MN8TOARS.
    10.1007/BF00058569
  87. Tomas, H.; Friere, A.P.; Abrantes, L.M.. "Cast Co-Cr alloy and pure chromium in proteinaceous media: An electrochemical characterization". Journal of Materials Science: Materials in Medicine 5 6-7 (1994): 446-451. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028445287&partnerID=MN8TOARS.
    10.1007/BF00058981
Magazine article
  1. Tomás, Helena. "A Química é divertida, Doze anos de promoção da Química na Madeira, Química (Boletim da Sociedade Portuguesa de Química), nº104, p.51-52 (2007).", 2007
Thesis / Dissertation
  1. "Corrosion behaviour and cytocompatibility evaluation of a Co-Cr-Mo orthopaedic alloy". PhD, Universidade de Lisboa, 1996.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2023/09/07 Tomás H.; Dendrimer-based nanomaterials for anticancer drug delivery; XL National Meeting of the Spanish Society of Pharmacology; Toledo, Spain; 6-8 September, page 38, 2023 (Invited keynote lecture)
2021 Castro R., Granja P. L., Rodrigues J., Pêgo A. P., Tomás H., Dendrimers and DNA: a promising marriage. XXVII Encontro Nacional Sociedade Portuguesa de Química (SPQ), Braga, Portugal 2021 (Invited)
2019 Tomás H., Rodrigues J., Laponite in drug delivery and tissue regeneration, MedTex19 & IFBMTM 2019, May 17-18, Shanghai, China, 2019 (Invited lecture)
2019 Tomás H., Laponite in nanomedicine, University of Donghua, Shanghai, China, 2019 (Invited lecture)
2019 H. Tomás, Designing nanomaterials for cancer cell targeting in therapeutics and diagnostics, First COST ACTION CA17140 Training School, Trieste, Italy (trainer in the school)
2013 Tomás H., Dendrimers and nucleic acid delivery, Donghua University, Shanghai (China, 2013) (Invited)
2012 Tomás H., Dendrimers and mesenchymal stem cells, Donghua University, Shanghai (China, 2012) (Invited)
2011 Tomás H., Different Strategies for Mesenchymal Stem Cells Differentiation, 8th Supraphone Meeting (Funchal, 2011) (Invited oral presentation)
2009 Tomás, H., Tissue regeneration via gene delivery, Summer Course on Biomaterials and Regenerative Medicine in the scope of the European Project BRIDGE (Funchal, 2009) (Invited)
2006 Tomás, H., Osteogenic differentiation - Extracellular Matrix Effects, 1st Annual International Meeting of the Portuguese Society for Stem Cells and Cellular Therapies, SPCE-TC (Funchal, 2006) (Keynote Lecture)
2006 Tomás, H., Tissue Engineering Research in Madeira – A Gene Delivery Approach,1st Marie Curie Cutting Edge InVENTS Conference on New Developments on Polymers for Tissue Engineering, Replacement and Regeneration (Funchal, 2006) (Keynote Lecture)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2022/09/15 - Current Laponite hydrogels for cisplatin delivery
Supervisor of Ana Sofia Duarte
 Mestrado em Bioquímica Aplicada (Master)
Universidade da Madeira, Portugal
2022/01/01 - Current Novel stimuli-responsive nanoplatforms for osteosarcoma treatment based on biodegradable bone-targeted dendrimers
Supervisor of Fátima Ferreira
 Chemistry (PhD)
2019/12/01 - Current Fucoidan/dendrimer-based nanosystems with targeting capabilities for glioblastoma theranostics
Supervisor of José Filipe Olim
 Chemistry (PhD)
Universidade da Madeira Centro de Química da Madeira, Portugal
2021/09/15 - 2022/11/04 Spheroid development for in vitro chondrogenesis
Supervisor of Filipa Jardim
 Master in Applied Biochemistry (Master)
Universidade da Madeira, Portugal
2017 - 2022 Post-DOCTORAl work: Ligand development by Phage Display Technology - application to bionanosensors for the diagnostic of infectious diseases. Grant from ARDITI (ARDITI-CQM/2017/009-PDG, in the scope of the project CQM+).
Supervisor of Mariana Vieira
 Chemistry (Other)
Universidade da Madeira Centro de Química da Madeira, Portugal
2018 - 2020 Laponite®-based nanogels for bone tissue regeneration
Supervisor of Fátima Ferreira
 Applied Biochemistry (Master)
2018 - 2019 Nanopartículas de colagénio para terapias da cartilagem baseadas em recursos marinhos
Supervisor of Francisca Costa
 Applied Biochemistry (Master)
2017 - 2019 Post-DOCTORAL work: Development of nanogels for biomedical applications based on marine resources (organic, inorganic or hybrid nanomaterials). Grant from ARDITI (ARDITI-CQM/2017/011-PDG, in the scope of the project CQM+)
Supervisor of Ana Rute Neves
 Chemistry (Other)
Universidade da Madeira Centro de Química da Madeira, Portugal
2013/09/01 - 2018/07/23 "DNA/Dendrimer-based films: a novel material with potential biomedical applications"
Supervisor of Rita Maria de Castro
 Chemistry (PhD)
Universidade da Madeira Centro de Química da Madeira, Portugal
2013/09/01 - 2018/07/05 Nanotechnology Approaches for the delivery of antitumor drugs, the case of doxorubicin
Supervisor of Mara Isabel Jesus Gonçalves
 Chemistry (PhD)
Universidade da Madeira Centro de Química da Madeira, Portugal
2011 - 2018 From 2011 until 2018, she supervised 14 Chinese students during internships at CQM (3 months) in the scope of an exchange program (Santander Chair) with the University of Donghua
Supervisor of -
 Chemistry (Other)
Universidade da Madeira Centro de Química da Madeira, Portugal
2016 - 2017 Preliminary studies on the use of exosomes as dendrimer carriers
Supervisor of Filipe Olim
 Applied Biochemistry (Master)
2013 - 2014 Gene delivery using dendrimer/pDNA complexes immobilized in electrospun fibers using the layer-by-layer technique
Supervisor of Kirthiga Ramalingam
Nanochemistry and Nanomaterials (Master)
2011 - 2014 Post-DOCTORAL work: New materials for biomedical applications obtained by the self-assembly of dendrimer-single stranded DNA conjugates. FCT grant (SFRH/BPD/75420/2010).
Supervisor
 Chemistry (Other)
Universidade da Madeira Centro de Química da Madeira, Portugal
2011 - 2012 Interação das células estaminais mesenquimais com um novo material de implante à base de hidroxiapatite e com multicamadas de polieletrólitos
Supervisor of Daniel Lima
 Applied Biochemistry (Master)
2009 - 2012 Post-DOCTORAL work: Biomimetic preparation of calcium phosphate nanoparticles using dendrimers as templates – application on gene delivery. FCT grant (SFRH/BPD/47369/2008).
Supervisor of Alireza Nouri
 Chemistry (Other)
Universidade da Madeira Centro de Química da Madeira, Portugal
2010 - 2011 New dendrimer-based vectors for antisense therapy
Supervisor of Rita Castro
 Applied Biochemistry (Master)
2010 - 2011 Avaliação do efeito dos dendrímeros com diferentes grupos funcionais na diferenciação de células estaminais mesenquimais
Supervisor of Mara Gonçalves
 Ciências Biomédicas (Master)
2009 - 2010 Encapsulation of single hMSCs in polyelectrolyte shells-preliminary studies
Supervisor of Neide Freitas
 Applied Biochemistry (Master)
2009 - 2010 Post-DOCTORAL work: Novel drug/gene delivery platforms based on the self-assembly of dendrimer-single strand DNA conjugates. FCT grant (SFRH/BPD/44821/2008).
Supervisor of Deepti Pandita
 Chemistry (Other)
Universidade da Madeira Centro de Química da Madeira, Portugal
2004/12/01 - 2009/09/18 Functionalization of Dendrimers for Improved Gene Delivery to Mesenchymal Stem Cells
Supervisor of José Luís Santos
 Chemistry (PhD)
Universidade da Madeira Centro de Química da Madeira, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2019 - Current Global Women’s Breakfast at CQM, in 2019, which has the general aim of Empowering Women in Science (2019)
Other (Other)
 Universidade da Madeira Centro de Química da Madeira, Portugal
2019 - Current Meeting of the Working Group 1 of COST Action CA17140: NANO2CLINIC-Cancer nanomedicine - from the bench to the bedside (Funchal, Portugal, 2019). (2019)
Workshop (Co-organisor)
 Universidade da Madeira Centro de Química da Madeira, Portugal
2014 - Current NanoSchool 2014 - Advanced School (Invited scientist: Prof. Ruth Duncan, Cardiff University) (2014)
Other (Other)
 Universidade da Madeira Centro de Química da Madeira, Portugal
2013 - Current Madeira's participation in the European project Future2020: How will life be in 2020? Call: FP7-PEOPLE-2013-NIGHT, project 609809 (European Researchers' Night 2013). During this event, among other activities, she organized a TV debate with Madeira local TV (RTP Madeira). (2013)
Other (Other)
 Universidade da Madeira, Portugal
2011 - Current FBPS 2011 - Frontiers in Biomedical Polymers (Funchal, Portugal, 2011) (2011)
Congress (Other)
2010 - Current NanoSchool 2010 - Advanced School (Invited scientist: Prof. Mathias Epple, University of Duisburg-Essen) (2010)
Other (Other)
 Universidade da Madeira Centro de Química da Madeira, Portugal
2009 - Current 5th European Symposium on Biopolymers (ESBP2009, Funchal, Portugal, 2009). (2009)
Congress (Co-organisor)
2009 - Current Summer Course on Biomaterials and Regenerative Medicine no âmbito do projeto europeu BRIDGE (Funchal, Portugal, 2009 (2009)
Other (Co-organisor)
2007 - Current Organization of CQM participation in a set of 3 television science programs for «Panda Channel» which is a TV channel dedicated to children (2007)
Other (Other)
 Universidade da Madeira Centro de Química da Madeira, Portugal
2007 - Current 3rd Marie Curie Cutting Edge Conference: Biomineralisation of polymeric materials, bioactive biomaterials and biomimetic methodologies (Funchal, Portugal, 2007) (2007)
Congress (Other)
2006 - Current 1st Annual International Meeting of the Portuguese Society for Stem Cells and Cellular Therapies, SPCE-TC (Funchal, Portugal, 2006) (2006)
Conference (Co-organisor)
2006 - Current 1st Marie Curie Cutting Edge InVENTS Conference on New Developments on Polymers for Tissue Engineering, Replacement and Regeneration (Funchal, Portugal, 2006) (2006)
Congress (Other)
2007 - 2019 Participation of CQM in the nationwide initiative promoted by the «Ciência Viva» agency, offering research internships for high school students during the summer (role: coordinator at CQM). (2007 - 2019)
Other (Other)
 Universidade da Madeira Centro de Química da Madeira, Portugal
2006 - 2019 A QUÍMICA É DIVERTIDA - SCIENCE DISSEMINATION ACTIVITY, Centro de Química da Madeira, Universidade da Madeira (open doors, funny experiments and visits to research labs) (2006 - 2019)
Other (Other)
 Universidade da Madeira Centro de Química da Madeira, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2023 Analytical and in vitro cytotoxicity studies of synthetic cannabinoids found in seized ‘herbal incenses’.
Thesis Member
 Vera Alves (PhD)
Universidade da Madeira, Portugal
2022 Magneto-plasmonic nanoassemblies using dendrimers: chemical synthesis and water quality monitoring
(Thesis) Main arguer
 Tiago Fernandes (PhD)
Instituto de Nanoestruturas Nanomodelação e Nanofabricação, Portugal
2019 Tissue Engineered In Vitro Models on a Chip for Cancer Research
(Thesis) Main arguer
 Mariana Carvalho (PhD)
Universidade do Minho, Portugal
2018 Nutraceuticals and functional foods for diabetes and obesity control
Thesis Member
 Vítor Spínola (PhD)
Universidade da Madeira, Portugal
2018 DNA/dendrimer-based films. A novel material with potential biomedical applications
Supervisor
 Rita Castro (PhD)
Universidade da Madeira, Portugal
2018 Nanotechnology approaches for the delivery of antitumor drugs. The case of doxorubicin.
Supervisor
 Mara Gonçalves (PhD)
Universidade da Madeira, Portugal
2015 Non-invasive strategy in assessing asthma through biofluids metabolomics exploration: exhaled breath and urine potentialities
Thesis Member
 Michael Caldeira (PhD)
2011 Computational and Experimental Strategies for Assessing the Conformational and Dynamic Properties of Proteins and peptides
Thesis Member
 Carla Alves (PhD)
Universidade da Madeira, Portugal
2009 New nanotecnology approaches using dendrimers modified with natural polymers for controlling stem cells behaviour in tissue engineering strategies.
(Thesis) Main arguer
 Joaquim Oliveira (PhD)
Universidade do Minho, Portugal
2009 Functionalization of dendrimers for improved gene delivery to mesenchymal stem cells.
Supervisor
 José Luís Santos (PhD)
2008 Osteochondral tissue engineering constructs combining particle aggregated scaffolding and bioactive delivery strategies
(Thesis) Main arguer
 Patrícia Malafaya Baptista (PhD)
Universidade do Minho, Portugal
2003 Erros hereditários das purinas e pirimidinas: diagnóstico diferencial e caracterização molecular.
Thesis Member
 Helena Caldeira Araújo (PhD)
2000 Estudo da influência dos ácidos gordos ¿-3 na composição dos lípidos e lipoproteínas do soro e na susceptibilidade das LDL à oxidação em dois grupos populacionais da ilha da Madeira
Thesis Member
 Isabel Torres (PhD)
Universidade da Madeira, Portugal
1999 Avaliação da biocompatibilidade de ligas metálicas ortopédicas: estudos in vitro e in vivo
(Thesis) Main arguer
 Isabel Bravo (PhD)
Universidade de Aveiro, Portugal

Association member

Society Organization name Role
1990/01/01 - Current SPQ-Sociedade Portuguesa de Química Effective member
1989/09/01 - Current Portuguese Order of the Engineer Specialty in Chemical and Biological Engineeering, Member number 29449 (effective), Level of qualification:E2

Consulting

Activity description Institution / Organization
2019 - Current International adviser for the project Biomedical Textile Materials and Technology (since 01/03/2019, PI: Lu Wang) from Donghua University, funded by “Plan 111” promoted by the Ministry of Education and the Chinese State Administration of Foreign Experts Affairs.

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
1995 - Current At the University of Madeira (Chemistry Department), she taught several courses, such as: General Chemistry, Biochemistry I and II, Cellular and Molecular Characterization Techniques (to the 1st Cycle in Biochemistry); Topics in Nanomedicine, Biomaterials and Tissue Engineering, Nanomaterials for Biomedical Applications (2nd Cycle in Applied Biochemistry and 2nd Cycle in Nanomaterials and Tissue Engineering).

Evaluation committee

Activity description
Role 		Institution / Organization Funding entity
2020 - Current She served as an expert for the Science Fund of the Republic of Serbia
Specialist
2020 - Current She served as an expert for the French Agence Nationale de la Recherche.
Specialist
2018 - Current She served FCT as an evaluator in the 2018 Call for PhD grants of FCT (Materials Engineering and Nanotechnologies Panel)
Specialist
2021 - 2024 She served as expert for the European Commission in the monitoring of two research projects: 1) HADEA/A/03 ENDOSCAPE, a clinically applicable non-viral gene delivery technology (2022, 2023); 2) EISMEA H2020-FETOPEN-2018-2019-2020-01-899549-SCANnTREAT (2021, 2022, 2024).
Specialist
2019 - 2024 She served as evaluator for the European Commission in the calls: 1) HORIZON-HLTH-2024-TOOL-11-02 (Bio-printing of living cells for regenerative medicine); 2) HORIZON-EIC-2024-PATHFINDEROPEN-01; 3) HORIZON-WIDERA-2023-ACCESS-06 (Hop-on facility); 4) HORIZON-HLTH-2021-TOOL-06-02 (Next generation advanced therapies to treat highly prevalent and high burden diseases with unmet medical needs); 5) SC1-BHC-07-2019 (Regenerative medicine: from new insights to new applications).
Specialist
2014 - 2022 She served FCT as an evaluator of final project reports (2014, 2019-2022).
Specialist
2016 - 2020 She served as an expert for the Latvian Central Finance and Contracting Agency (2016-2020).
Specialist

Interview (tv / radio show)

Program Topic
2018 - Current EM ENTREVISTA (RTP Madeira) - Episódio 22 (2018) Nanomedicina
2020/08/15 - 2020/10/10 No Feminino - Antena 1 Madeira (conversas sobre a atualidade)

Journal scientific committee

Journal title (ISSN) Publisher
2021/01/15 - Current Pharmaceutics (1999-4923) MDPI
2013 - Current Biomed Research International (Biomaterials area) (2314-6141) Hindawi Publishing Corporation
Distinctions

Other distinction

2019 Best Poster Presentation Award at the 11th International Dendrimers Symposium (student: Rita Castro)
2019 Member of the Portuguese Committee for the commemoration of the International Year of the Periodic Table of the Chemical Elements 2019.
2018 Portuguese Representative in the COST Action CA17140 NANO2CLINIC - Cancer nanomedicine - from the bench to the bedside (2018-2022) European Union funded.
Fundação para a Ciência e a Tecnologia, Portugal
2011 Portuguese Representative in the COST Action TD0802: Dendrimers in Biomedical Applications. (2010-2013) European Union funded.
Fundação para a Ciência e a Tecnologia, Portugal
2009 Best oral presentation at the 5th European Symposium on Biopolymers, ESBP 2009 (student: José Luís Santos)