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Luca Gasperini. Completed the Dottorato di Ricerca in N/A in 2013/04/15 by Università degli Studi di Trento, Dottorato di Ricerca in Biomaterials in 2015/04/15 by Università degli Studi di Trento and Dottorato di Ricerca in N/A in 2013 by Università degli Studi di Trento. Is Postdoc in Universidade do Minho, Postdoc in Laboratório Associado ICVS 3B's and Postdoc in Biomaterials Biodegradables and Biomimetics. Published 10 articles in journals. Has 1 patent(s) registered. Works in the area(s) of Engineering and Technology with emphasis on Materials Engineering. In their professional activities interacted with 50 collaborator(s) co-authorship of scientific papers. In his curriculum Ciência Vitae the most frequent terms in the context of scientific, technological and artistic-cultural output are: Chondroitin sulfate; Fiber-based techniques; Hyaluronic acid; Microfluidics; Polyelectrolyte complexation; Tendon; microfludics; Science & Technology; Gellan gum; Octadecylamine; Physical hydrogels; Thermal scanning rheology; Mechanical properties; Growth factor immobilization; Hydrogel; Cell encapsulation; Hydrogels; Natural polymers; Microencapsulation; Adipose-derived stem cells; Hydrogel;; Injectable; Methacrylated gellan gum; Osteogenic differentiation; Bioprinting; Cell viability; Cell-laden hydrogels; Osmotic regulator; Sucrose; Biomaterials; Polymers; Microfibers; Microfluidic technique; Drug delivery; Hydrogel fibers; .
Identification

Personal identification

Full name
Luca Gasperini

Citation names

  • Gasperini, Luca

Author identifiers

Ciência ID
1310-03A5-C495
ORCID iD
0000-0003-2133-4379

Knowledge fields

  • Engineering and Technology - Materials Engineering

Languages

Language Speaking Reading Writing Listening Peer-review
Italian (Mother tongue)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Portuguese Beginner (A1) Intermediate (B1) Beginner (A1) Beginner (A1)
Education
Degree Classification
2013/04/15
Concluded
Biomaterials (Dottorato di Ricerca)
Università degli Studi di Trento, Italy
"Strategies for cells encapsulation and deposition" (THESIS/DISSERTATION)
Excellent
2009/10/26
Concluded
Materials Engineering (Laurea)
Major in Biomaterials
Università degli Studi di Trento, Italy
"Strategies for neural regeneration" (THESIS/DISSERTATION)
Affiliation

Science

2013/11/01 - Current Postdoc (Research)
Biomaterials Biodegradables and Biomimetics, Portugal
2013/11/01 - Current Postdoc (Research)
Laboratório Associado ICVS 3B's, Portugal
Projects

Other

Designation Funders
2017 - Current Automated high-content screening of YAP/TAZ as intracellular mechanosensing rheostat and therapeutic target in a 3D hepatocellular carcinoma microspheroid model for pre-clinical drug development
PTDC/BTM-ORG/31564/2017
Biomaterials Biodegradables and Biomimetics, Portugal
2014 - Current A novel bi-compartmentalized hydrogel microcapsule as 3D co-culture system for liver tissue microengineering and drug-induced hepatotoxicity screening
P2020-PTDC/BBB-ECT/4317/2014
Pos-doctoral Fellow
Biomaterials Biodegradables and Biomimetics, Portugal
Associação para a Inovação e Desenvolvimento da FCT
2018 - 2019/01/31 ECM_INK
ERC-2016- COG-726061
Pos-doctoral Fellow
Biomaterials Biodegradables and Biomimetics, Portugal
European Research Council
2013 - 2018/04/01 ComplexiTE
ERC-2012-ADG 20120216-321266
Pos-doctoral Fellow
Biomaterials Biodegradables and Biomimetics, Portugal
European Research Council
Outputs

Publications

Conference abstract
  1. Gasperini, Luca; Carvalho, A. F.; Ribeiro, R. S.; Marques, A. P.; Reis, R. L.. 2019. "Segmented microfibers as high-throughput platform to screen 3D cell-materials interactions". Paper presented in Termis Europe 2019, Rhodes, Greece, 600.
    Accepted
  2. Guimarães, C. F.; Gasperini, Luca; Ribeiro, R. S.; Pinto, A. C.; Carvalho, A. F.; Marques, A. P.; Reis, R. L.. 2019. "Microfluidic fabrication of 3D biomaterial libraries for high-throughput screening stem cell responses". Paper presented in Termis Europe 2019, Rhodes, Greece, 378.
    Published
  3. Gasperini, Luca; Carvalho, A. F.; Ribeiro, R. S.; Marques, A. P.; Reis, R. L.. 2017. "Microfluidic oil-free fabrication of multiple 3D platforms to screen cell-material interactions". Paper presented in Termis Europe, Davos, Switzerland.
    Published
  4. DK Bishi; Gasperini, Luca; Marques, A. P.; Mano, J. F.; Reis, R. L.. 2015. "Development of Janus hydrogel microcapsules as novel biomaterials-stem cells construct for 3D co-culture applications". Paper presented in Termis World, Boston, United States.
    Published • 10.1089/ten.tea.2015.5000.abstracts
  5. Agnello, Stefano; Gasperini, Luca; Reis, R. L.; Mano, J. F.; Pitarresi, Giovanna; Palumbo, Fabio S.; Giammona, Gaetano. 2015. "Production of hyaluronic acid derivative microfibers with controlled dimension as potential drug delivery system". Paper presented in Bio Tecnologie Ricerca di base interdisciplinare traslazione in ambito biomedico, Italy.
  6. Gasperini, Luca; Mano, J. F.; Reis, R. L.. 2015. "A microfluidic strategy for oil-free cell encapsulation". Paper presented in TermStem 2015.
  7. Gasperini, Luca; Mano, J. F.; Reis, R. L.. 2014. "High-throughput microencapsulation of cells in microparticles formulated using mixtures of distinct natural-based macromolecules".
  8. Volha Liaudanskaya; Gasperini, Luca; Antonella Motta; Claudio Migliaresi. 2012. "Organ printing and stem cells as future of regenerative medicine: influence of the cell encapsulation system on cell behavior.". Paper presented in TermStem 2012, Guimarães, Portugal, 21-21.
    Published • 10.1002/term.1608
Conference paper
  1. Guimarães, Carlos; Gasperini, Luca; Ribeiro, R. S.; Carvalho, A. F.; Marques, A. P.; Reis, R. L.. 2018. "From low-to high-throughput: Microfluidic fabrication of novel 3D biomaterial libraries for screening cell responses". Paper presented in ESB 2018, Maastrich, Netherlands.
    Accepted
  2. Custódio, Catarina Almeida; Gasperini, Luca; Reis, R. L.; Mano, J. F.. 2015. "Cell type specific microspheres incorporating growth factors as injectable cell carriers for tissue repair". Portugal: Mary Ann Liebert Inc..
    10.1089/ten.tea.2015.5000.abstracts
  3. Costa-Almeida, R.; Gasperini, Luca; Rodrigues, Márcia T.; Babo, P. M.; Mano, J. F.; Reis, R. L.; Gomes, Manuela E.. 2015. "Development of biomimetic microengineered hydrogel fibers for tendon regeneration". Portugal: Mary Ann Liebert.
    10.1089/ten.tea.2015.5000.abstracts
Conference poster
  1. Gasperini, Luca; Carvalho, A. F.; Ribeiro, R. S.; Marques, A. P.; Reis, R. L.. 2018. "Multicomponent hydrogel patches for wound healing". Paper presented in GeneSkin 2018.
  2. Carvalho, A. F.; Ribeiro, R. S.; Gasperini, Luca; Silva, L.P; Marques, A. P.; Reis, R. L.. 2018. "High-throughput screening of optimal osteogenic differentiation conditions in Gellan Gum hydrogel microfibers". Paper presented in ESB 2018.
  3. Gasperini, Luca; Carvalho, A. F.; Ribeiro, R. S.; Marques, A. P.; Reis, R. L.. 2018. "Microfilm-inspired high-throughput platform to screen 3D cell-materials interactions". Paper presented in Termis World 2018.
  4. Gasperini, Luca; Carvalho, A. F.; Ribeiro, R. S.; Marques, A. P.; Reis, R. L.. 2018. "Segmented fibers-based high-throughput platform to screen 3D cellmaterials interactions". Paper presented in TermStem 2018.
  5. Gasperini, Luca; Carvalho, A. F.; Ribeiro, R. S.; Marques, A. P.; Reis, R. L.. 2017. "Microfluidic oil-free fabrication of multiple 3D platforms to screen cell-material interactions". Paper presented in Termstem 2017.
  6. Agnello, Stefano; Gasperini, Luca; Mano, J. F.; Pitarresi, Giovanna; Palumbo, Fabio S.; Giammona, Gaetano; Reis, R. L.. 2016. "Hyaluronic acid and gellan gum derivatives for tissue engineering and drug release". Paper presented in TermStem 2016.
  7. Gasperini, Luca; Claudio Migliaresi; Devid Maniglio. 2011. "Electro Hydro Dynamic (ehd) Encapsulation of Cells in Alginate Based Hydrogels". Paper presented in XXXVIII Congress of the European Society for Artificial Organs.
    10.1111/j.1525-1594.2011.01336.x
Journal article
  1. Stefano Agnello; Luca Gasperini; João F. Mano; Giovanna Pitarresi; Fabio S. Palumbo; Rui L. Reis; Gaetano Giammona. 2017. "Synthesis, mechanical and thermal rheological properties of new gellan gum derivatives". International Journal of Biological Macromolecules 98: 646-653. https://doi.org/10.1016%2Fj.ijbiomac.2017.02.029.
    10.1016/j.ijbiomac.2017.02.029
  2. A F Carvalho; L Gasperini; R S Ribeiro; A P Marques; R L Reis. 2017. "Control of osmotic pressure to improve cell viability in cell-laden tissue engineering constructs". Journal of Tissue Engineering and Regenerative Medicine. https://doi.org/10.1002%2Fterm.2432.
    10.1002/term.2432
  3. Patuzzo, S.; Goracci, G.; Ciliberti, R.; Gasperini, L.. 2017. "3D Bioprinting Technology: Scientific Aspects and Ethical Issues". Science and Engineering Ethics: 1-14. http://www.scopus.com/inward/record.url?eid=2-s2.0-85025131235&partnerID=MN8TOARS.
    10.1007/s11948-017-9918-y
  4. Raquel Costa-Almeida; Luca Gasperini; João Borges; Pedro S. Babo; Márcia T. Rodrigues; João F. Mano; Rui L. Reis; Manuela E. Gomes. 2016. "Microengineered Multicomponent Hydrogel Fibers: Combining Polyelectrolyte Complexation and Microfluidics". ACS Biomaterials Science & Engineering. https://doi.org/10.1021%2Facsbiomaterials.6b00331.
    10.1021/acsbiomaterials.6b00331
  5. Stefano Agnello; Luca Gasperini; Rui L. Reis; João F. Mano; Giovanna Pitarresi; Fabio S. Palumbo; Gaetano Giammona. 2016. "Microfluidic production of hyaluronic acid derivative microfibers to control drug release". Materials Letters. http://dx.doi.org/10.1016/j.matlet.2016.07.014.
    10.1016/j.matlet.2016.07.014
  6. Mariana B. Oliveira; Catarina A. Custódio; Luca Gasperini; Rui L. Reis; João F. Mano. 2016. "Autonomous osteogenic differentiation of hASCs encapsulated in methacrylated gellan-gum hydrogels". Acta Biomaterialia. http://dx.doi.org/10.1016/j.actbio.2016.05.033.
    10.1016/j.actbio.2016.05.033
  7. Luca Gasperini; Devid Maniglio; Antonella Motta; Claudio Migliaresi. 2015. "An Electrohydrodynamic Bioprinter for Alginate Hydrogels Containing Living Cells". Tissue Engineering Part C: Methods 21 (2): 123-132. http://dx.doi.org/10.1089/ten.tec.2014.0149.
    10.1089/ten.tec.2014.0149
  8. Volha Liaudanskaya; Luca Gasperini; Devid Maniglio; Antonella Motta; Claudio Migliaresi. 2014. "Assessing the Impact of Electrohydrodynamic Jetting on Encapsulated Cell Viability, Proliferation, and Ability to Self-Assemble in Three-Dimensional Structures". Tissue Engineering Part C: Methods: 150127064141009-150127064141009. http://dx.doi.org/10.1089/ten.tec.2014.0228.
    10.1089/ten.tec.2014.0228
  9. L. Gasperini; J. F. Mano; R. L. Reis. 2014. "Natural polymers for the microencapsulation of cells". Journal of The Royal Society Interface 11 (100): 20140817-20140817. http://dx.doi.org/10.1098/rsif.2014.0817.
    10.1098/rsif.2014.0817
  10. L. Gasperini; D. Maniglio; C. Migliaresi. 2013. "Microencapsulation of cells in alginate through an electrohydrodynamic process". Journal of Bioactive and Compatible Polymers 28 (5): 413-425. http://dx.doi.org/10.1177/0883911513501599.
    10.1177/0883911513501599

Intellectual property

Patent
  1. Gasperini, Luca. 2018. "Fibers With Segments, Their Preparation And Applications Thereof".
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2017 Rheological properties of gellan gum for biomedical applications Chem2Nature
3B's (Portugal)
2016 Exploring amphiphilic derivatives of carbohydrate polymers for biomedical applications Chem2Nature
3B's (Portugal)

Supervision

Thesis Title
Role
Degree Subject (Type)
Institution / Organization
2018/09 - Current Establishing a Dynamic In Vitro System to Enhance the Functionality of 3D-Bioprinted Skin-like Constructs
Co-supervisor
Biomaterials Biodegradables and Biomimetics, Portugal
2017/09/05 - Current High-Throughput Fabrication, Screening and Sorting of 3D Cell-Biomaterial Constructs towards Combinatorial Tissue Engineering.
Co-supervisor
Biomaterials (PhD)
Biomaterials Biodegradables and Biomimetics, Portugal

Event organisation

Event name
Type of event (Role)
Institution / Organization
2016/10/24 - 2018/10/26 Organization of 5 Gene2skin conferences and schools (talks, posters and activities) (2016/10/24 - 2018/10/26) Biomaterials Biodegradables and Biomimetics, Portugal

Mentoring / Tutoring

Topic Student name
2015/03 - 2015/11 Characterization of new carbohydrate derivatives Stefano Agnello
2012/01 - 2013/09 Assessing the Impact of Electrohydrodynamic Jetting on Encapsulated Cell Viability, Proliferation, and Ability to Self-Assemble in Three-Dimensional Structures. Volha Liaudanskaya
2012/11 - 2013/03 Bioprinting Silvia Lucchi