???global.info.a_carregar???
Luca Gasperini. Completed the Dottorato di Ricerca in N/A in 2013/04/15 by Università degli Studi di Trento, Dottorato di Ricerca in Biomaterials in 2015/04/15 by Università degli Studi di Trento and Dottorato di Ricerca in N/A in 2013 by Università degli Studi di Trento. Is Postdoc in Universidade do Minho, Postdoc in Laboratório Associado ICVS 3B's and Postdoc in Biomaterials Biodegradables and Biomimetics. Published 10 articles in journals. Has 1 patent(s) registered. Works in the area(s) of Engineering and Technology with emphasis on Materials Engineering. In their professional activities interacted with 50 collaborator(s) co-authorship of scientific papers. In his curriculum Ciência Vitae the most frequent terms in the context of scientific, technological and artistic-cultural output are: Chondroitin sulfate; Fiber-based techniques; Hyaluronic acid; Microfluidics; Polyelectrolyte complexation; Tendon; microfludics; Science & Technology; Gellan gum; Octadecylamine; Physical hydrogels; Thermal scanning rheology; Mechanical properties; Growth factor immobilization; Hydrogel; Cell encapsulation; Hydrogels; Natural polymers; Microencapsulation; Adipose-derived stem cells; Hydrogel;; Injectable; Methacrylated gellan gum; Osteogenic differentiation; Bioprinting; Cell viability; Cell-laden hydrogels; Osmotic regulator; Sucrose; Biomaterials; Polymers; Microfibers; Microfluidic technique; Drug delivery; Hydrogel fibers; .
Identificação

Identificação pessoal

Nome completo
Luca Gasperini

Nomes de citação

  • Gasperini, Luca
  • Gasperini, L.
  • Luca Gasperini
  • L. Gasperini
  • L Gasperini

Identificadores de autor

Ciência ID
1310-03A5-C495
ORCID iD
0000-0003-2133-4379

Domínios de atuação

  • Ciências da Engenharia e Tecnologias - Engenharia dos Materiais

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Italiano (Idioma materno)
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Português Utilizador elementar (A1) Utilizador independente (B1) Utilizador elementar (A1) Utilizador elementar (A1)
Formação
Grau Classificação
2013/04/15
Concluído
Biomaterials (Dottorato di Ricerca)
Università degli Studi di Trento, Itália
"Strategies for cells encapsulation and deposition" (TESE/DISSERTAÇÃO)
Excellent
2009/10/26
Concluído
Materials Engineering (Laurea)
Especialização em Biomaterials
Università degli Studi di Trento, Itália
"Strategies for neural regeneration" (TESE/DISSERTAÇÃO)
Percurso profissional

Ciência

2013/11/01 - Atual Pós-doutorado (Investigação)
Biomaterials Biodegradables and Biomimetics, Portugal
2013/11/01 - Atual Pós-doutorado (Investigação)
Laboratório Associado ICVS 3B's, Portugal
Projetos

Outro

Designação Financiadores
2017 - Atual Automated high-content screening of YAP/TAZ as intracellular mechanosensing rheostat and therapeutic target in a 3D hepatocellular carcinoma microspheroid model for pre-clinical drug development
PTDC/BTM-ORG/31564/2017
Biomaterials Biodegradables and Biomimetics, Portugal
2014 - Atual A novel bi-compartmentalized hydrogel microcapsule as 3D co-culture system for liver tissue microengineering and drug-induced hepatotoxicity screening
P2020-PTDC/BBB-ECT/4317/2014
Bolseiro de Pós-Doutoramento
Biomaterials Biodegradables and Biomimetics, Portugal
Associação para a Inovação e Desenvolvimento da FCT
2018 - 2019/01/31 ECM_INK
ERC-2016- COG-726061
Bolseiro de Pós-Doutoramento
Biomaterials Biodegradables and Biomimetics, Portugal
European Research Council
2013 - 2018/04/01 ComplexiTE
ERC-2012-ADG 20120216-321266
Bolseiro de Pós-Doutoramento
Biomaterials Biodegradables and Biomimetics, Portugal
European Research Council
Produções

Publicações

Artigo em revista
  1. Carlos F. Guimarães; Luca Gasperini; Alexandra P. Marques; Rui L. Reis. "The stiffness of living tissues and its implications for tissue engineering". Nature Reviews Materials (2020): https://doi.org/10.1038/s41578-019-0169-1.
    10.1038/s41578-019-0169-1
  2. Stefano Agnello; Luca Gasperini; João F. Mano; Giovanna Pitarresi; Fabio S. Palumbo; Rui L. Reis; Gaetano Giammona. "Synthesis, mechanical and thermal rheological properties of new gellan gum derivatives". International Journal of Biological Macromolecules 98 (2017): 646-653. https://doi.org/10.1016%2Fj.ijbiomac.2017.02.029.
    10.1016/j.ijbiomac.2017.02.029
  3. A F Carvalho; L Gasperini; R S Ribeiro; A P Marques; R L Reis. "Control of osmotic pressure to improve cell viability in cell-laden tissue engineering constructs". Journal of Tissue Engineering and Regenerative Medicine (2017): https://doi.org/10.1002%2Fterm.2432.
    10.1002/term.2432
  4. Patuzzo, S.; Goracci, G.; Ciliberti, R.; Gasperini, L.. "3D Bioprinting Technology: Scientific Aspects and Ethical Issues". Science and Engineering Ethics (2017): 1-14. http://www.scopus.com/inward/record.url?eid=2-s2.0-85025131235&partnerID=MN8TOARS.
    10.1007/s11948-017-9918-y
  5. Raquel Costa-Almeida; Luca Gasperini; João Borges; Pedro S. Babo; Márcia T. Rodrigues; João F. Mano; Rui L. Reis; Manuela E. Gomes. "Microengineered Multicomponent Hydrogel Fibers: Combining Polyelectrolyte Complexation and Microfluidics". ACS Biomaterials Science & Engineering (2016): https://doi.org/10.1021%2Facsbiomaterials.6b00331.
    10.1021/acsbiomaterials.6b00331
  6. Stefano Agnello; Luca Gasperini; Rui L. Reis; João F. Mano; Giovanna Pitarresi; Fabio S. Palumbo; Gaetano Giammona. "Microfluidic production of hyaluronic acid derivative microfibers to control drug release". Materials Letters (2016): http://dx.doi.org/10.1016/j.matlet.2016.07.014.
    10.1016/j.matlet.2016.07.014
  7. Mariana B. Oliveira; Catarina A. Custódio; Luca Gasperini; Rui L. Reis; João F. Mano. "Autonomous osteogenic differentiation of hASCs encapsulated in methacrylated gellan-gum hydrogels". Acta Biomaterialia (2016): http://dx.doi.org/10.1016/j.actbio.2016.05.033.
    10.1016/j.actbio.2016.05.033
  8. Luca Gasperini; Devid Maniglio; Antonella Motta; Claudio Migliaresi. "An Electrohydrodynamic Bioprinter for Alginate Hydrogels Containing Living Cells". Tissue Engineering Part C: Methods 21 2 (2015): 123-132. http://dx.doi.org/10.1089/ten.tec.2014.0149.
    10.1089/ten.tec.2014.0149
  9. Volha Liaudanskaya; Luca Gasperini; Devid Maniglio; Antonella Motta; Claudio Migliaresi. "Assessing the Impact of Electrohydrodynamic Jetting on Encapsulated Cell Viability, Proliferation, and Ability to Self-Assemble in Three-Dimensional Structures". Tissue Engineering Part C: Methods (2014): 150127064141009-150127064141009. http://dx.doi.org/10.1089/ten.tec.2014.0228.
    10.1089/ten.tec.2014.0228
  10. L. Gasperini; J. F. Mano; R. L. Reis. "Natural polymers for the microencapsulation of cells". Journal of The Royal Society Interface 11 100 (2014): 20140817-20140817. http://dx.doi.org/10.1098/rsif.2014.0817.
    10.1098/rsif.2014.0817
  11. L. Gasperini; D. Maniglio; C. Migliaresi. "Microencapsulation of cells in alginate through an electrohydrodynamic process". Journal of Bioactive and Compatible Polymers 28 5 (2013): 413-425. http://dx.doi.org/10.1177/0883911513501599.
    10.1177/0883911513501599
Capítulo de livro
  1. Gasperini, Luca. "Microfluidics for Processing of Biomaterials.". 2020.
    10.1007/978-3-030-36588-2_2
Poster em conferência
  1. Reis Daniel; Fidalgo, Càtia; Gasperini, Luca; Rui L. Reis; Marques, A. P.. "Bio-tailored gellan gum-based bioinks". Trabalho apresentado em Termis Europe workshop 2019, 2019.
  2. Gasperini, Luca; Carvalho, A. F.; Ribeiro, R. S.; Marques, A. P.; Reis, R. L.. "Multicomponent hydrogel patches for wound healing". Trabalho apresentado em GeneSkin 2018, 2018.
  3. Carvalho, A. F.; Ribeiro, R. S.; Gasperini, Luca; Silva, L.P; Marques, A. P.; Reis, R. L.. "High-throughput screening of optimal osteogenic differentiation conditions in Gellan Gum hydrogel microfibers". Trabalho apresentado em ESB 2018, 2018.
  4. Gasperini, Luca; Carvalho, A. F.; Ribeiro, R. S.; Marques, A. P.; Reis, R. L.. "Microfilm-inspired high-throughput platform to screen 3D cell-materials interactions". Trabalho apresentado em Termis World 2018, 2018.
  5. Gasperini, Luca; Carvalho, A. F.; Ribeiro, R. S.; Marques, A. P.; Reis, R. L.. "Segmented fibers-based high-throughput platform to screen 3D cellmaterials interactions". Trabalho apresentado em TermStem 2018, 2018.
  6. Gasperini, Luca; Carvalho, A. F.; Ribeiro, R. S.; Marques, A. P.; Reis, R. L.. "Microfluidic oil-free fabrication of multiple 3D platforms to screen cell-material interactions". Trabalho apresentado em Termstem 2017, 2017.
  7. Agnello, Stefano; Gasperini, Luca; Mano, J. F.; Pitarresi, Giovanna; Palumbo, Fabio S.; Giammona, Gaetano; Reis, R. L.. "Hyaluronic acid and gellan gum derivatives for tissue engineering and drug release". Trabalho apresentado em TermStem 2016, 2016.
  8. Agnello, Stefano; Gasperini, Luca; Mano, J. F.; Pitarresi, Giovanna; Palumbo, Fabio S.; Giammona, Gaetano; Reis, Rui L.. "Production of hyaluronic acid derivative microfibers with controlled dimension as potential drug delivery system". Trabalho apresentado em Biotecnologie: Ricerca di Base, Interdisciplinare e Traslazionale in Ambito Biomedico, 2015.
  9. Gasperini, Luca; Claudio Migliaresi; Devid Maniglio. "Electro Hydro Dynamic (ehd) Encapsulation of Cells in Alginate Based Hydrogels". Trabalho apresentado em XXXVIII Congress of the European Society for Artificial Organs, 2011.
    10.1111/j.1525-1594.2011.01336.x
Resumo em conferência
  1. Gasperini, Luca; Ribeiro, R. S.; Carvalho, Andreia; Marques, A. P.; Reis, R. L.. "Gellan gum rheological properties and bioprinting". Trabalho apresentado em Termis Europe workshop 2019, Nantes, 2019.
    Publicado
  2. Gasperini, Luca; Carvalho, A. F.; Ribeiro, R. S.; Marques, A. P.; Reis, R. L.. "Segmented microfibers as high-throughput platform to screen 3D cell-materials interactions". Trabalho apresentado em Termis Europe 2019, Rhodes, 2019.
    Aceite para publicação
  3. Guimarães, C. F.; Gasperini, Luca; Ribeiro, R. S.; Pinto, A. C.; Carvalho, A. F.; Marques, A. P.; Reis, R. L.. "Microfluidic fabrication of 3D biomaterial libraries for high-throughput screening stem cell responses". Trabalho apresentado em Termis Europe 2019, Rhodes, 2019.
    Publicado
  4. Guimarães, Carlos; Gasperini, Luca; Ribeiro, R. S.; Carvalho, A. F.; Marques, A. P.; Reis, R. L.. "From low-to high-throughput: Microfluidic fabrication of novel 3D biomaterial libraries for screening cell responses". Trabalho apresentado em ESB 2018, Maastrich, 2018.
    Aceite para publicação
  5. Gasperini, Luca; Carvalho, A. F.; Ribeiro, R. S.; Marques, A. P.; Reis, R. L.. "Microfluidic oil-free fabrication of multiple 3D platforms to screen cell-material interactions". Trabalho apresentado em Termis Europe, Davos, 2017.
    Publicado
  6. DK Bishi; Gasperini, Luca; Marques, A. P.; Mano, J. F.; Reis, R. L.. "Development of Janus hydrogel microcapsules as novel biomaterials-stem cells construct for 3D co-culture applications". Trabalho apresentado em Termis World, Boston, 2015.
    Publicado • 10.1089/ten.tea.2015.5000.abstracts
  7. Agnello, Stefano; Gasperini, Luca; Reis, R. L.; Mano, J. F.; Pitarresi, Giovanna; Palumbo, Fabio S.; Giammona, Gaetano. "Production of hyaluronic acid derivative microfibers with controlled dimension as potential drug delivery system". Trabalho apresentado em Bio Tecnologie Ricerca di base interdisciplinare traslazione in ambito biomedico, 2015.
  8. Gasperini, Luca; Mano, J. F.; Reis, R. L.. "A microfluidic strategy for oil-free cell encapsulation". Trabalho apresentado em TermStem 2015, 2015.
  9. Gasperini, Luca; Mano, J. F.; Reis, R. L.. "High-throughput microencapsulation of cells in microparticles formulated using mixtures of distinct natural-based macromolecules". 2014.
  10. Volha Liaudanskaya; Gasperini, Luca; Antonella Motta; Claudio Migliaresi. "Organ printing and stem cells as future of regenerative medicine: influence of the cell encapsulation system on cell behavior.". Trabalho apresentado em TermStem 2012, Guimarães, 2012.
    Publicado • 10.1002/term.1608

Propriedade Intelectual

Patente
  1. Gasperini, Luca. 2018. "Fibers With Segments, Their Preparation And Applications Thereof".
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2019/08 Rheological properties of gellan gum for bioprinting Termis-EU Workshop 3D Printing in Cancer Research
Termis (Nantes, França)
2019/05 Microfluidic fabrication of 3D biomaterial libraries for high-throughput screening stem cell responses Termis European Chapter Meeting
Termis (Rhodes, Grécia)
2019/05 Segmented microfibers as a high-throughput platform to screen 3D cell-materials interactions Termis European Chapter Meeting
Termis (Rhodes, Grécia)
2018/09 From low- to high-throughput: Microfluidic fabrication of novel 3D biomaterial libraries for screening cell responses 29th European Conference on Biomaterials
Europeans Society Biomaterials (Maastricht, Países Baixos)
2018/08 High-throughput screening of optimal osteogenic differentiation conditions 29th European Conference on Biomaterials
Europeans Society Biomaterials (Maastricht, Países Baixos)
2018/06 From low to high-throughput: Development of a 3D Gellan Gum gradient to screen the effect of hydrogel mechanics on ASC commitment Chem2Nature Summer School on Multifunctional biomedical devices
3Bs (Porto, Portugal)
2017/06 Rheological properties of gellan gum for biomedical applications Chem2Nature Second School
3Bs (Porto, Portugal)
2017/06 Microfluidic oil-free fabrication of multiple 3D platforms to screen cell-material interactions Termis European Chapter Meeting
Termis (Davos, Suiça)
2016/11 Screening of 3D cell-materials interactions: A Microfluidic approach Chem2Nature First School
3Bs (Guimarães, Portugal)
2016/11 Development of Janus droplet generation device for hepatocyte-endothelial cell co-culture applictions Chem2Nature First School
3Bs (Guimarães, Portugal)
2016/10 A Microfluidic-Based Platform for the Screening of 3D Cell-Biomaterials Interactions TermStem
3Bs (Guimarães, Portugal)
2016 Exploring amphiphilic derivatives of carbohydrate polymers for biomedical applications Chem2Nature
3B's (Portugal)
2015/06 A microfluidic strategy for oil-free cell encapsulation Polaris
3Bs (Guimarães, Portugal)
2014/10 High-throughput microencapsulation of cells in microparticles formulated using mixtures of distinct natural-based macromolecules TermStem
3Bs (Porto, Portugal)
2014/10 Three dimensional co-cultures in janus-like hydrogel microcapsules TermStem
3Bs (Porto, Portugal)

Orientação

Título / Tema
Papel desempenhado
Curso (Tipo)
Instituição / Organização
2018/09 - Atual Establishing a Dynamic In Vitro System to Enhance the Functionality of 3D-Bioprinted Skin-like Constructs
Coorientador
Biomaterials Biodegradables and Biomimetics, Portugal
2017/09/05 - Atual High-Throughput Fabrication, Screening and Sorting of 3D Cell-Biomaterial Constructs towards Combinatorial Tissue Engineering.
Coorientador
Biomaterials (Doutoramento)
Biomaterials Biodegradables and Biomimetics, Portugal

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação)
Instituição / Organização
2016/10/24 - 2018/10/26 Organization of 5 Gene2skin conferences and schools (talks, posters and activities) (2016/10/24 - 2018/10/26)
Conferência (Membro da Comissão Organizadora)
Biomaterials Biodegradables and Biomimetics, Portugal

Tutoria

Tópico Nome do aluno
2015/03 - 2015/11 Characterization of new carbohydrate derivatives Stefano Agnello
2012/01 - 2013/09 Assessing the Impact of Electrohydrodynamic Jetting on Encapsulated Cell Viability, Proliferation, and Ability to Self-Assemble in Three-Dimensional Structures. Volha Liaudanskaya
2012/11 - 2013/03 Bioprinting Silvia Lucchi