???global.info.a_carregar???
Professor in Biomedical Sciences and Medical Microbiology, Vice-Director of the Institute of Hygiene and Tropical Medicine, Scientific Coordinator of the Research Unit Global Health and Tropical Medicine and Vice-Coordinator of the Associate Laboratory in Translation and Innovation Towards Global Health, LA-REAL (UID/04413/2020 and LA/P/0117/2020), NOVA University of Lisbon, Portugal. Scientific Director of the UNESCO Center Ciência LP [https://www.ciencialp.pt/]: ------ a) Devoted to the early diagnosis and molecular epidemiology of TB and new therapeutics for MDRTB and XDRTB. Specialist in the diagnosis of antibiotic resistance in bacteria by phenotypic and genotypic assays; ------ b) Studied, in the last 20 years, the contribution of the efflux-pumps and membrane transporters to bacterial multidrug resistant phenotypes especially in mycobacteria, and how we can prevent, reverse or reduce the level of resistance and recover the effectiveness of the antibiotics to which the bacteria became resistant. Interested in the molecular biology and epidemiology of mycobacteria, nanotechnology, drug design and development, immunology, molecular epidemiology and whole genome sequencing of TB focused on the early diagnosis of multidrug/extensively drug resistant TB and other antibiotic resistant bacterial infections; ------- c) Executive committee member of the Study Group for Mycobacterial Infections of the European Society of Clinical Microbiology and Infectious Diseases and Vice-President of the Portuguese Society for Microbiology. Member of the evaluation panel of EU Research Programs (Horizon 2020, Horizon Europe, COST Action), Individual Doctoral and Post-doctoral Grant proposals - Fundação para a Ciencia e a Tecnologia - Ministério da Educação e Ciencia de Portugal and ESCMID Grants. Expert Evaluator for "MRC South Africa" calls (area Tuberculosis), Welcome Trust and Fundação Osvaldo Cruz, Brasil. Ad-hoc reviewer for the expert panel of the Mark Wainberg Fellowship Programme (Africa) of the International AIDS Society Educational Fund, The Research Foundation - Flanders (FWO)/Belgium and Swiss National Science Foundation. ------ d) Completed the Habilitation Degree in Biomedical Sciences on 04/2019/2012 from the Universidade Nova de Lisboa Institute of Hygiene and Tropical Medicine, PhD in Biology in 2001 from the University of Lisbon, Master's degree in Biotechnology (Engineering Biochemistry) in 1993/10/01 from the University of Lisbon Instituto Superior Técnico and Degree in Biology in 1991/10/01 from the University of Lisbon Faculty of Sciences; ------- e) Full Professor at the Universidade Nova de Lisboa Institute of Hygiene and Tropical Medicine, Scientific/technical-scientific Council or corresponding body at the Universidade Nova de Lisboa Institute of Hygiene and Tropical Medicine and Coordination or direction of a research center, department or equivalent at Universidade Nova de Lisboa Global Health and Tropical Medicine.; ------- f) Scopus H-index of 54. Published 228 articles in specialized journals. Has 10 book chapter(s) and 3 book(s). Supervised 6 post-docs and 10 doctoral thesis(s). Sup/Co-supervised 35 master's dissertation(s). Participates and/or participated as a PhD Fellow in 1 project(s), Investigator in 23 project(s) and Responsible Investigator in 13 project(s). He works in the area(s) of Medical and Health Sciences. Interacted with 3465 collaborator(s) in co-authoring scientific works; ------- g) The most frequent terms in the context of scientific, technological and artistic-cultural production are: Bioinformatics; Epidemiology; Genomic analysis; Mixed infections; M. tuberculosis; Tuberculosis; Efflux inhibitors; Efflux pumps; resistance; Synergism; Thioridazine; Portugal; Drug resistance; 3-Phenylquinolones; Antimicrobial resistance; Efflux pump inhibitors; M; avium complex; Nontuberculous mycobacteria; activation; KatG; membrane; mutation
Identificação

Identificação pessoal

Nome completo
Miguel Viveiros Bettencourt

Nomes de citação

  • Viveiros, Miguel

Identificadores de autor

Ciência ID
DF17-B4BF-8756
ORCID iD
0000-0001-9676-6251
Google Scholar ID
o39byr4AAAAJ
Researcher Id
A-7326-2008
Scopus Author Id
7003949212

Websites

Domínios de atuação

  • Ciências Médicas e da Saúde

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Francês Utilizador independente (B1) Utilizador proficiente (C1) Utilizador independente (B1) Utilizador independente (B1)
Espanhol; Castelhano Utilizador independente (B1) Utilizador proficiente (C1) Utilizador independente (B1) Utilizador independente (B1)
Formação
Grau Classificação
2012/04/19
Concluído
Ciências Biomédicas (Título de Agregado)
Especialização em Ciências Biomédicas
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
"“As novas tecnologias de biologia molecular no diagnóstico precoce da tuberculose resistente: a sua integração e monitorização no contexto dos programas de controlo da tuberculose”. " (TESE/DISSERTAÇÃO)
Aprovado com Louvor e Distinção
2001
Concluído
Biologia (Doutoramento)
Universidade de Lisboa, Portugal
"Molecular Genetics of Carotenogenesis in Mycobacterium : Cloning and Study of the Mycobacterium Carotenogenic Operon and Application in the Development of a New Efficient Gene Expression System for the Isolation of Genes Associated in Mycobacterium Tuberc" (TESE/DISSERTAÇÃO)
1993/10/01
Concluído
Biotecnologia (Engenharia Bioquímica) (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
18/20
1991/10/01
Concluído
Biologia (Licenciatura)
Especialização em Microbiologia
Universidade de Lisboa Faculdade de Ciências, Portugal
16/20
Percurso profissional

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento
Empregador
2013/07/01 - Atual Professor Catedrático (Docente Universitário) Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal

Cargos e Funções

Categoria Profissional
Instituição de acolhimento
Empregador
2020/03/15 - Atual Coordenação ou direção de centro de investigação, departamento ou equivalente Universidade Nova de Lisboa Saúde Global e Medicina Tropical, Portugal
Universidade Nova de Lisboa Saúde Global e Medicina Tropical, Portugal
2010 - Atual Conselho científico/técnico-científico ou orgão correspondente Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2015 - 2020 Conselho geral ou orgão correspondente Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2010 - 2020 Conselho pedagógico Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
Projetos

Bolsa

Designação Financiadores
1995/01 - 1997/12 GENÉTICA MOLECULAR DA CAROTENOGÉNESE EM MYCOBACTERIUM
2443DFA
PRAXIS XXI/BD/3962/94
Provided by PTCRIS: PRAXIS XXI/BD/3962/94
Bolseiro de Doutoramento
Universidade de Lisboa Faculdade de Ciências, Portugal
Fundação para a Ciência e a Tecnologia
Concluído

Projeto

Designação Financiadores
2021/01/01 - 2025/12/31 Associated Laboratory of Translation and Innovation for Global Health (REAL)
LA/P/0117/2020
Co-Investigador Responsável (Co-IR)
Universidade Nova de Lisboa Saúde Global e Medicina Tropical, Portugal

Universidade Nova de Lisboa, Portugal

Universidade NOVA de Lisboa Comprehensive Health Research Centre, Portugal

Universidade de Lisboa Faculdade de Medicina Dentária, Portugal

Universidade de Coimbra, Portugal

Universidade de Évora, Portugal

Universidade Nova de Lisboa ¿Laboratório de Instrumentação Engenharia Biomédica e Física da Radiação, Portugal

Universidade NOVA de Lisboa, Portugal

Universidade de Évora, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2021/01 - 2025/12 Translação e Inovação para a Saúde Global
168254UID
Co-Investigador Responsável (Co-IR)
Fundação para a Ciência e a Tecnologia
2019/01/01 - 2024/12/31 Global Health and Tropical Medicine
UID/Multi/04413/2019
UIDB/04413/2020
154718UID
UIDP/04413/2020
Co-Investigador Responsável (Co-IR)
Universidade Nova de Lisboa Saúde Global e Medicina Tropical, Portugal

Universidade Nova de Lisboa, Portugal

Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal

Universidade NOVA de Lisboa, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2023/01 - 2024/06 Explorando a inibição de efluxo para o combate à resistência aos antimicrobianos e a biofilmes em estafilococos
175487PRJ
Provided by PTCRIS: 2022.07931.PTDC
2022.07931.PTDC
Universidade NOVA de Lisboa, Portugal

Universidade Nova de Lisboa, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2022/01 - 2023/12 Efeitos não específicos da vacina BCG em crianças com menos de 5 anos de vida
168477PRJ
EXPL/SAU-EPI/0067/2021
Investigador
Universidade NOVA de Lisboa, Portugal

Universidade Nova de Lisboa Saúde Global e Medicina Tropical, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2020/01 - 2023/12 Saúde Global e Medicina Tropical
157866UID
Co-Investigador Responsável (Co-IR)
Fundação para a Ciência e a Tecnologia
Em curso
2020/01 - 2023/12 Saúde Global e Medicina Tropical
157551UID
Co-Investigador Responsável (Co-IR)
Fundação para a Ciência e a Tecnologia
Em curso
2018/10 - 2022/09 O uso de biocidas na prevenção da resistência aos antimicrobianos na comunidade.
151907PRJ
PTDC/CAL-EST/30713/2017
Investigador
Universidade Nova de Lisboa, Portugal

Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal

Universidade NOVA de Lisboa, Portugal

Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2018/11/15 - 2021/11/14 Imunoterapias contra sistemas de efluxo para modulação de bactérias multiresistentes
PTDC/BTM-SAL/30550/2017
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Universidade Nova de Lisboa, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Universidade NOVA de Lisboa, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2020/07 - 2021/10/30 Ion channel blockers mechanism of action against SARS-CoV-2/COVID-19: a fast-track ex-vivo study to complement the current on-going clinical trials
747202047188FAC
434
Investigador responsável
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
Fundação para a Ciência e a Tecnologia

Associação para a Inovação e Desenvolvimento da FCT
Concluído
2018/10/01 - 2021/09/30 Identificação de novos tratamentos antimaláricos através de uma abordagem de "reposicionamento de fármacos" centrada no alvo
PTDC/SAU-PAR/28459/2017
Investigador
Universidade Nova de Lisboa, Portugal

Universidade NOVA de Lisboa, Portugal

Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2018/10/01 - 2021/09/30 Bombas de efluxo como alvos terapêuticos em Mycobacterium tuberculosis resistente aos antibióticos: uma abordagem para prevenir a resistência mediada por efluxo e potenciar a terapêutica na tuberculose activa e latente
PTDC/BIA-MIC/30692/2017
151884PRJ
Investigador responsável
Universidade Nova de Lisboa, Portugal

Universidade NOVA de Lisboa, Portugal

Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2018/10/01 - 2021/09/30 Em busca de novos derivados de isoniazida eficazes no combate à tuberculose multi-resistente: uma abordagem integrada de química medicinal
PTDC/MED-QUI/29036/2017
150239PRJ
Investigador
Universidade Nova de Lisboa, Portugal

FCiênciasID Associação para a Investigação e Desenvolvimento de Ciências, Portugal

Universidade NOVA de Lisboa, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2018/10 - 2021/09 Targeting multi-resistant tuberculosis with new potent isoniazid derivatives: an integrated medicinal chemistry approach
Provided by PTCRIS: PTDC/MED-QUI/29036/2017
Investigador
Fundação para a Ciência e a Tecnologia
Concluído
2018/10 - 2021/09 Targeting efflux pumps in drug resistant Mycobacterium tuberculosis: an approach to prevent efflux-mediated resistance and boost therapy in active and latent tuberculosis
Provided by PTCRIS: PTDC/BIA-MIC/30692/2017
Investigador responsável
Fundação para a Ciência e a Tecnologia
Concluído
2018/10 - 2021/09 Preventing antimicrobial resistance in the community - the safe use of biocides.
Provided by PTCRIS: PTDC/CAL-EST/30713/2017
Investigador
Fundação para a Ciência e a Tecnologia
Concluído
2018/10 - 2021/09 Identification of new antimalarial treatments through a target-centred "drug repositioning" approach
Provided by PTCRIS: PTDC/SAU-PAR/28459/2017
Investigador
Fundação para a Ciência e a Tecnologia
2018/09/01 - 2021/08/31 Líquidos Iónicos Farmaceuticos como uma nova plataforma para o tratamento efectivo da Tuberculose (TB-ILs)
PTDC/QUI-QOR/32406/2017
Investigador
Associação para a Inovação e Desenvolvimento da FCT, Portugal

Universidade Nova de Lisboa, Portugal

Universidade NOVA de Lisboa, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2018/09 - 2021/08 Active Pharmaceutical Ionic Liquids as new platform for Effective Treatment of Tuberculosis TB-ILs
Provided by PTCRIS: PTDC/QUI-QOR/32406/2017
PTDC/QUIQOR/32406/2017.
PTDC/QUIQOR/32406/2017.
Investigador
Fundação para a Ciência e a Tecnologia
Concluído
2018 - 2021 BYDRUG: Immunotargeting efflux systems for therapeutic modulation of multidrug resistant bacteria
PTDC/BTMSAL/30550/2017
Provided by PTCRIS: PTDC/BTM-SAL/30550/2017
Investigador
Fundação para a Ciência e a Tecnologia
Concluído
2018/04/01 - 2020/03/31 Chemogenomics and in silico repurposing as an innovative approach for rapid drug discovery in tuberculosis
Investigador responsável
Universidade Nova de Lisboa Saúde Global e Medicina Tropical, Portugal

Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
EUROPEAN COMMISSION Research Executive Agency
Concluído
2018 - 2020 MagNanoP-TB/HIV: Aplicação de nanopartículas superparamagnéticas no diagnóstico rápido, simultâneo e não invasivo da infeção pelo VIH e da tuberculose
PGG/012/2017
Investigador responsável
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
Gilead Sciences Lda
Em curso
2015/01/01 - 2018/12/31 Saúde Global e Medicina Tropical
UID/Multi/04413/2013
Investigador
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal

Universidade Nova de Lisboa Saúde Global e Medicina Tropical, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2015/01 - 2018/12 Saúde Global e Medicina Tropical
147267UID
Investigador
Fundação para a Ciência e a Tecnologia
Concluído
2015/05/01 - 2018/04/30 HAITool - Antibiotic Stewardship Organizational and Informationals System Design and Implementation
Co-Investigador Responsável (Co-IR)
Universidade Nova de Lisboa Saúde Global e Medicina Tropical, Portugal
EEA Grants
Concluído
2013/01 - 2017/01 Caracterização do mecanismo de efluxo relacionado à resistência aos antimicrobianos e aos antitumorais e desenvolvimento de novos fármacos inibidores deste mecanismo
Investigador responsável
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
Concluído
2013/06 - 2015/12 OSYRISH - Sistema Organizacional e Informacional para melhorar a Comunicação na gestão das Infecções Aquiridas em Hospitais
132200PRJ
PTDC/IVC-COM/5016/2012
Provided by PTCRIS: PTDC/IVC-COM/5016/2012
Co-Investigador Responsável (Co-IR)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal

Instituto de Engenharia de Sistemas e Computadores Inovação, Portugal

Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas, Portugal

Karolinska Institutet, Suécia
Fundação para a Ciência e a Tecnologia

Fundação para a Ciência e a Tecnologia
Concluído
2012/03 - 2015/03 Type-II NADH-menaquinone oxidoreductase (NDH-2) and the respiratory chain of M. tuberculosis: new therapeutic targets to fight tuberculosis.
PTDC/BIA-MIC/121859/2010
Provided by PTCRIS: PTDC/BIA-MIC/121859/2010
121859PRJ
Investigador
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal

Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal

Associação para a Inovação e Desenvolvimento da FCT, Portugal

Unidade de Ciências Biomoleculares Aplicadas, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
Fundação para a Ciência e a Tecnologia

Fundação para a Ciência e a Tecnologia
Concluído
2011/01 - 2013/12 Projecto Estratégico - UI 74 - 2011-2012
123377UID
PEst-OE/SAU/UI0074/2011
Investigador
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal

Universidade Nova de Lisboa Unidade de Ensino e Investigação de Parasitologia Médica, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2010/03/01 - 2013/08/31 Aumento da capacidade de morte (killing activity) de macrófagos humanos infectados por Mycobacterium tuberculosis multi-resistente (MDRTB): uma nova estratégia quimioterapêutica para combater a tuberculose multi-resistente.
PTDC/SAU-FCF/102807/2008
102807PRJ
Investigador responsável
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal

Universidade Nova de Lisboa Unidade de Ensino e Investigação de Parasitologia Médica, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2010/03 - 2013/08 Helper compounds against multidrug resistant bacteria: revealing their mechanism of action
Provided by PTCRIS: PTDC/BIA-MIC/105509/2008
Investigador responsável
Fundação para a Ciência e a Tecnologia

Fundação para a Ciência e a Tecnologia
Concluído
2010/03 - 2013/08 Enhancing the killing of intracellular multi-drug resistant tuberculosis MDRTB by human macrophages: a new chemotherapeutic strategy to fight MDRTB.
Provided by PTCRIS: PTDC/SAU-FCF/102807/2008
Investigador responsável
Fundação para a Ciência e a Tecnologia

Fundação para a Ciência e a Tecnologia
Concluído
2010/03 - 2013/08 Descrição do mecanismo de acção de adjuvantes da antibioterapia de bactérias multirresistentes
105509PRJ
PTDC/BIA-MIC/105509/2008
Investigador responsável
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal

Universidade de Lisboa Instituto Superior Técnico, Portugal

Universidade Nova de Lisboa Unidade de Ensino e Investigação de Parasitologia Médica, Portugal

Instituto de Biotecnologia e Bioengenharia, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2009/02 - 2012/08 Do Design à Síntese de Novos Agentes Anti-Tuberculares
67933PRJ
Provided by PTCRIS: PTDC/QUI/67933/2006
PTDC/QUI/67933/2006
Investigador
Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal

Universidade de Lisboa Centro de Química e Bioquímica, Portugal

Universidade de Lisboa Faculdade de Farmácia, Portugal

Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal

Universidade de Lisboa Faculdade de Ciências, Portugal
Fundação para a Ciência e a Tecnologia

Fundação para a Ciência e a Tecnologia
Concluído
2008/01/01 - 2011/06/30 Dinâmica fisiológica e mutacional da resistência aos antibióticos em Mycobacterium tuberculosis: a emergência da Tuberculose Multi-Resistente.
PTDC/BIA-MIC/71280/2006
71280PRJ
Investigador responsável
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal

Universidade Nova de Lisboa Unidade de Ensino e Investigação de Parasitologia Médica, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2008/01 - 2011/06 Mutational and physiological dynamics of drug resistance in Mycobacterium tuberculosis: the emergence of Multi-Drug Resistant Tuberculosis.
Provided by PTCRIS: PTDC/BIA-MIC/71280/2006
Investigador responsável
Fundação para a Ciência e a Tecnologia

Fundação para a Ciência e a Tecnologia
Concluído
2007/01 - 2009/06 Efflux-pumps in drug resistance of Mycobacterium tuberculosis: Molecular characterisation of the efflux mechanism and use of efflux inhibitors as new anti-tubercular compounds
Provided by PTCRIS: POCI/SAU-MMO/59370/2004
Investigador responsável
Fundação para a Ciência e a Tecnologia

Fundação para a Ciência e a Tecnologia
Concluído
2005/07 - 2007/12 Bombas de efluxo em Mycobacterium tuberculosis: caracterizacão molecular dos mecanismos de efluxo e uso de inibidores de efluxo como novos compostos anti-bacilares
59370PRJ
POCI/SAU-MMO/59370/2004
Investigador responsável
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal

Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal

Universidade de Lisboa Instituto Superior Técnico, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
Produções

Publicações

Artigo em conferência
  1. Perdigão, João; Silva, Carla; Diniz, Jaciara; Pereira, Catarina; Machado, Diana; Ramos, Jorge; Silva, Hugo; et al. "Mycobacterium tuberculosis genetic diversity and drug resistance across Portuguese-speaking countries and CPLP-TB: a novel framework and surveillance tool for the Lusophone community". 2019.
  2. Sofia Santos Costa; Mafalda Rosa; Ana Catarina Rodrigues; Cláudia Mineiro Santos; Frederico Holtreman; Miguel Viveiros; Constança Pomba; Isabel Couto. "Emergence of non-wild-type populations towards biocides and antibiotic resistance in Staphylococcus epidermidis colonizing veterinary staff and students". 2018.
  3. Santos Costa, Sofia; Santos, Cláudia Mineiro; Viveiros, Miguel; Pomba, Constança. "Frequent biofilm production by Staphylococcus epidermidis causing infection in pets or colonizing veterinary staff". 2018.
  4. Santos Costa, Sofia; Rosato, Adriana E.; Viveiros, Miguel; Couto, Isabel. "Development of multidrug resistance in staphylococci driven by efflux". 2018.
  5. Santos Costa, Sofia; Rosa, Mafalda; Belas, Adriana; Viveiros, Miguel; Pomba, Constança; Couto, Isabel. "Biocide susceptibility in Staphylococcus epidermidis causing infection in pets". 2018.
  6. Costa, SS; Rosato, Adriana E.; Viveiros, M; Couto, I. "Development of multidrug resistance in staphylococci driven by efflux". 2018.
  7. Costa, SS; Kadlec, Kristina; Viveiros, M; Melo-Cristino, Josè; Schwarz, Stefan; Couto, I; Sofia Santos Costa; et al. "Complete sequences of two Staphylococcus aureus plasmids carrying genes for resistance to antibiotics, heavy-metals, biocides and/or virulence". 2018.
  8. Costa, SS; Rosa, Mafalda; Belas, Adriana; Viveiros, M; Pomba, Constança; Couto, I. "Biocide susceptibility in Staphylococcus epidermidis causing infection in pets". 2018.
  9. Costa, SS; Santos, Cláudia Mineiro; Viveiros, M; Pomba, Constança. "Frequent biofilm production by Staphylococcus epidermidis causing infection in pets or colonizing veterinary staff". 2018.
  10. Sofia Santos Costa; Mafalda Rosa; Ana Catarina Rodrigues; Frederico Holtreman; Miguel Viveiros; Constança Pomba; Isabel Couto. "Antibiotic and biocide resistance in Staphylococcus epidermidis colonizing humans in close contact with animals". 2017.
  11. Isabel Couto; Sofia Santos Costa; Diana Machado; Miguel Viveiros. "Microbial multiresistance in the era of global challenges – an urgent need for new approaches and technologies". 2017.
  12. Santos, Cláudia Mineiro; Costa, SS; Viveiros, Miguel; Pomba, Constança; Couto, I. "Prevalence of biofilm production in Staphylococcus epidermidis colonizing veterinary staff and students". 2017.
  13. Costa, SS; Rosa, Mafalda; Rodrigues, Ana Catarina; Holtreman, Frederico; Viveiros, Miguel; Pomba, Constança; Couto, I. "Antibiotic and biocide resistance in Staphylococcus epidermidis colonizing humans in close contact with animals". 2017.
  14. Holtreman, Frederico; Costa, SS; Rosa, Mafalda; Viveiros, Miguel; Pomba, Constança; Couto, I. "Characterization of plasmid encoded efflux determinants from Staphylococcus epidermidis". 2017.
  15. Costa, SS; Rosa, Mafalda; Rodrigues, Ana Catarina; Santos, Cláudia Mineiro; Holtreman, Frederico; Viveiros, Miguel; Pomba, Constança; Couto, I. "Characterization of antimicrobial resistance in Staphylococcus epidermidis colonizing veterinary staff and students". 2017.
  16. Costa, SS; Rosa, Mafalda; Rodrigues, Ana Catarina; Holtreman, Frederico; Viveiros, M; Pomba, Constança; Couto, I. "Antibiotic and biocide resistance in Staphylococcus epidermidis colonizing humans in close contact with animals". 2017.
  17. Costa, SS; Rosa, Mafalda; Rodrigues, Ana Catarina; Santos, Cláudia Mineiro; Holtreman, Frederico; Viveiros, M; Pomba, Constança; Couto, I. "Characterization of antimicrobial resistance in Staphylococcus epidermidis colonizing veterinary staff and students". 2017.
  18. Diana Machado; Elisa Azzali; Sofia Santos Costa; Gabriele Costantino; Isabel Couto; Marco Pieroni; Miguel Viveiros. "Antimycobacterial and efflux inhibitory activity of 2-aminothiazole lead compound against Mycobacterium tuberculosis". 2016.
  19. Elizeth Lopes; Sofia Santos Costa; Diana Machado; Marco Pieroni; Elisa Azzali; Gabriele Costantino; Miguel Viveiros; Isabel Couto. "Mycobacterium smegmatis model for the rapid screening of new compounds with efflux inhibitory and antimycobacterial activity". 2015.
  20. Perdigão, João; Clemente, Sofia; Ramos, Jorge; Masakidi, Pedro; Machado, Diana; Silva, Carla; Couto, Isabel; et al. "Drug resistance and genetic diversity of Mycobacterium tuberculosis in Luanda, Angola: a molecular epidemiological perspective". 2015.
  21. Perdigão, João; Clemente, Sofia; Ramos, Jorge; Masakidi, Pedro; Machado, Diana; Silva, Carla; Couto, Isabel; et al. "Drug resistance and genetic diversity of Mycobacterium tuberculosis in Luanda, Angola: a molecular epidemiological perspective". 2015.
  22. Sofia Santos Costa; Elisabete Junqueira; Cláudia Palma; Miguel Viveiros; Josè Melo-Cristino; Leonard Amaral; Isabel Couto. "Clinical relevance of efflux systems to antimicrobial resistance in Staphylococcus aureus". 2013.
  23. Leonard Amaral; Miguel Viveiros; Alexandru, T; Pascu, ML; Danko, B; Nastasa, V; Boni, M; et al. "Generation and biological evaluation of the pproducts formed from the exposure of phenothiazine to a 266 nm laser beam.". 2013.
    10.1117/12.2032666
  24. Perdigão, João; Macedo, Rita; Machado, Diana; Silva, Carla; Jordão, Luísa; Couto, Isabel; Viveiros, Miguel; Portugal, Isabel. "Polymorphism in gidB gene as a genetic marker for the mycobacterium tuberculosis Q1 cluster and implications for the streptomycin resistance level". 2013.
  25. Perdigão, João; Macedo, Rita; Machado, Diana; Silva, Carla; Jordão, Luísa; Couto, Isabel; Viveiros, Miguel; Portugal, Isabel. "Polymorphism in gidB gene as a genetic marker for the mycobacterium tuberculosis Q1 cluster and implications for the streptomycin resistance level". 2013.
  26. Perdigao, joão; Macedo, Rita; Machado, Diana; Silva, Carla; Jordão, Luísa; Couto, Isabel; Viveiros, Miguel; Portugal, Isabel. "Correlation between streptomycin intermediate-level resistance and gidB mutation in an endemic multidrugresistant tuberculosis cluster". 2013.
  27. Perdigão, João; Silva, Hugo; Machado, Diana; Macedo, Rita; Maltez, Fernando; Silva, Carla; Jordão, Luísa; et al. "Genomic diversity of drug-resistant mycobacterium tuberculosis isolates in Lisbon Portugal: towards tuberculosis genomic epidemiology". 2013.
  28. Perdigao, Joao; Silva, D.; Pereira, V.; Macedo, Rita; Silva, Carla; Machado, Diana; Couto, Isabel; et al. "Dynamics and Development of Extensively Drug-resistant Tuberculosis, Portugal". 2012.
  29. Perdigao, Joao; Silva, D.; Pereira, V.; Macedo, Rita; Silva, Carla; Machado, Diana; Couto, Isabel; et al. "Dynamics and Development of Extensively Drug-resistant Tuberculosis, Portugal". 2012.
  30. Silva, Carla; Perdigão, João; Couto, Isabel; Viveiros, Miguel; Jordão, Luísa; Portugal, Isabel. "Deletion analysis on multidrug resistant Mycobacterium tuberculosis in Portugal". 2011.
  31. Silva, Carla; Perdigão, João; Couto, Isabel; Viveiros, Miguel; Jordão, Luísa; Portugal, Isabel. "Deletion analysis on multidrug resistant Mycobacterium tuberculosis in Portugal". 2011.
  32. Leonard Amaral; Gabriella Spengler; Liliana Rodrigues; Ana Martins; Marta Martins; Sofia Santos Costa; Isabel Couto; Miguel Viveiros. "Efflux pumps of bacteria and cancer cells". 2010.
Artigo em revista
  1. Miriam Girardini; Diana Machado; Giannamaria Annunziato; Bianca Papotti; Marcella Palumbo; Chiara Spaggiari; Gabriele Costantino; Miguel Viveiros; Marco Pieroni. "Preliminary structure-activity relationships analysis on N-(3,5-dichlorophenyl)-4,5-dihydronaphtho[1,2-d]thiazol-2-amine, a disruptor of mycobacterial energetics". Medicinal Chemistry Research 33 3 (2024): 518-531. https://novaresearch.unl.pt/en/publications/c92754bf-e047-4045-b898-45d0fdb06c53.
    10.1007/s00044-024-03198-z
  2. Wind Duarte Augusto; Joana Paula Mendes da Paixão; Miguel Viveiros; Santos de Morais Nicolau. "Sensitivity profile of pathogens identified in the diagnosis of urinary infection by uroculture carried out at the National Institute for Health Research, Luanda/Angola, during the pre - pandemic, intra - pandemic and post - pandemic of COVID 19". Brazilian Journal of Clinical Medicine and Review (2024): https://doi.org/10.52600/2965-0968.bjcmr.2024.2.4.3-14.
    10.52600/2965-0968.bjcmr.2024.2.4.3-14
  3. Thiago da Silva Santos Malaquias; Eunice Petris Ribeiro; Tatiana Cristina Pereira Dutra; Marina Ricardo; Richard Salvato; Marcela Bhering; Daniella Castanheira Bartholomeu; et al. "The performance of Xpert MTB/RIF and MTBDRplus within a Programmatic setting at TB Laboratory in Rio de Janeiro, Brazil". Revista da Sociedade Brasileira de Medicina Tropical (2024): https://doi.org/10.1590/0037-8682-0167-2024.
    10.1590/0037-8682-0167-2024
  4. Paulo Ferrinho; Miguel Viveiros; Inês Fronteira. "Antimicrobial resistance, society and environment: A glocal syndemic". One Health (2023): https://app.dimensions.ai/details/publication/pub.1155483019.
    10.1016/j.onehlt.2023.100512
  5. Fröberg G; Maurer FP; Chryssanthou E; Fernström L; Benmansour H; Boarbi S; Mengshoel AT; et al. "Towards clinical breakpoints for non-tuberculous mycobacteria - Determination of epidemiological cut off values for the Mycobacterium avium complex and Mycobacterium abscessus using broth microdilution.". Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases (2023): http://europepmc.org/abstract/med/36813087.
    10.1016/j.cmi.2023.02.007
  6. Carolina Ferreira; Patrícia Abrantes; Sofia Santos Costa; Miguel Viveiros; Isabel Couto; Ferreira, Carolina; Abrantes, Patrícia; et al. "Occurrence and Variability of the Efflux Pump Gene norA across the Staphylococcus Genus". International Journal of Molecular Sciences (2022): https://doi.org/10.3390/ijms232315306.
    10.3390/ijms232315306
  7. Kritski AL; Viveiros M; Carvalho ACC. "Rapid molecular diagnostics to detect resistance to second-line anti-TB drugs.". The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease (2022): http://europepmc.org/abstract/med/35505483.
    10.5588/ijtld.22.0121
  8. Liliana Rodrigues; Renata Bento Cunha; Tatiana Vassilevskaia; Miguel Viveiros; Celso Cunha. "Drug Repurposing for COVID-19: A Review and a Novel Strategy to Identify New Targets and Potential Drug Candidates". Molecules (2022): https://doi.org/10.3390/molecules27092723.
    10.3390/molecules27092723
  9. Antimycobacterial Susceptibility Testing Group; Antimycobacterial Susceptibility Testing Group:. "Updating the approaches to define susceptibility and resistance to anti-tuberculosis agents: implications for diagnosis and treatment.". The European respiratory journal (2022): http://europepmc.org/abstract/med/35422426.
    10.1183/13993003.00166-2022
  10. Bateson A; Ortiz Canseco J; McHugh TD; Witney AA; Feuerriegel S; Merker M; Kohl TA; et al. "Ancient and recent differences in the intrinsic susceptibility of Mycobacterium tuberculosis complex to pretomanid.". The Journal of antimicrobial chemotherapy (2022): http://europepmc.org/abstract/med/35260883.
    10.1093/jac/dkac070
  11. Marques, Joaquim Trigo; De Faria, Catarina Frazao; Reis, Marina; Machado, Diana; Santos, Susana; Santos, Maria da Soledade; Viveiros, Miguel; et al. "In vitro Evaluation of Isoniazid Derivatives as Potential Agents Against Drug-Resistant Tuberculosis". Frontiers in Pharmacology (2022): https://publons.com/publon/52849536/.
    10.3389/FPHAR.2022.868545
  12. Rodrigues, Liliana; Cunha, Renata Bento; Vassilevskaia, Tatiana; Viveiros, Miguel; Cunha, Celso. "Drug Repurposing for COVID-19". (2022): http://hdl.handle.net/10362/140465.
    https://doi.org/10.3390/molecules27092723
  13. Deisy M. G. C. Rocha; Miguel Viveiros; Margarida Saraiva; Nuno S. Osório; Rocha, Deisy M.G.C.; Viveiros, Miguel; Saraiva, Margarida; Osório, Nuno S.. "The Neglected Contribution of Streptomycin to the Tuberculosis Drug Resistance Problem". Genes (2021): https://doi.org/10.3390/genes12122003.
    10.3390/genes12122003
  14. Catarina Frazão de Faria; Tânia Moreira; Pedro Lopes; Henrique Costa; Jessica R. Krewall; Callie M. Barton; Susana Santos; et al. "Designing new antitubercular isoniazid derivatives with improved reactivity and membrane trafficking abilities". Biomedicine and Pharmacotherapy 144 (2021): 1-9. https://novaresearch.unl.pt/en/publications/482da6fa-647a-4c4a-ae4d-dc52aa56f7d3.
    10.1016/j.biopha.2021.112362
  15. Jaciara de Lourdes do Carmo Guimarães Diniz; Andrea von Groll; Gisela Unis; Elis Regina Dalla-Costa; Maria Lúcia Rosa Rossetti; Júlia Silveira Vianna; Daniela Fernandes Ramos; et al. "Whole-genome sequencing as a tool for studying the microevolution of drug-resistant serial Mycobacterium tuberculosis isolates". Tuberculosis 131 (2021): 1-9. https://novaresearch.unl.pt/en/publications/9dd0fcf4-b3b6-4d3b-8a5b-82f31683e0c9.
    10.1016/j.tube.2021.102137
  16. Ortiz M; Jauset-Rubio M; Skouridou V; Machado D; Viveiros M; Clark TG; Simonova A; et al. "Electrochemical Detection of Single-Nucleotide Polymorphism Associated with Rifampicin Resistance in Mycobacterium tuberculosis Using Solid-Phase Primer Elongation with Ferrocene-Linked Redox-Labeled Nucleotides.". ACS sensors (2021): http://europepmc.org/abstract/med/34797987.
    10.1021/acssensors.1c01710
  17. Gómez-González PJ; Perdigao J; Gomes P; Puyen ZM; Santos-Lazaro D; Napier G; Hibberd ML; et al. "Genetic diversity of candidate loci linked to Mycobacterium tuberculosis resistance to bedaquiline, delamanid and pretomanid.". Scientific reports (2021): http://europepmc.org/abstract/med/34593898.
    10.1038/s41598-021-98862-4
  18. Salvato RS; Reis AJ; Schiefelbein SH; Gómez MAA; Salvato SS; da Silva LV; Costa ERD; et al. "Genomic-based surveillance reveals high ongoing transmission of multidrug-resistant Mycobacterium tuberculosis in Southern Brazil.". International journal of antimicrobial agents (2021): http://europepmc.org/abstract/med/34289403.
    10.1016/j.ijantimicag.2021.106401
  19. Rodrigues L; Aínsa JA; Viveiros M. "Measuring Efflux and Permeability in Mycobacteria.". Methods in molecular biology (Clifton, N.J.) (2021): http://europepmc.org/abstract/med/34235655.
    10.1007/978-1-0716-1460-0_9
  20. Viveiros, Miguel. "Editorial: Tuberculosis and Non-tuberculous Mycobacteria Infections: Control, Diagnosis and Treatment". (2021): https://publons.com/publon/50452611/.
    10.3389/fpubh.2021.666187
  21. Ortiz, Mayreli; Jauset-Rubio, Miriam; Skouridou, Vasso; Machado, Diana; Viveiros, Miguel; Clark, Taane G.; Simonova, Anna; et al. "Electrochemical Detection of Single-Nucleotide Polymorphism Associated with Rifampicin Resistance in Mycobacterium tuberculosis Using Solid-Phase Primer Elongation with Ferrocene-Linked Redox-Labeled Nucleotides". (2021): http://hdl.handle.net/10362/130385.
    https://doi.org/10.1021/acssensors.1c01710
  22. Gómez-González, Paula J.; Perdigao, Joao; Gomes, Pedro; Puyen, Zully M.; Santos-Lazaro, David; Napier, Gary; Hibberd, Martin L.; et al. "Genetic diversity of candidate loci linked to Mycobacterium tuberculosis resistance to bedaquiline, delamanid and pretomanid". (2021): http://hdl.handle.net/10362/127473.
    https://doi.org/10.1038/s41598-021-98862-4
  23. Salvato, Richard Steiner; Reis, Ana Júlia; Schiefelbein, Sun Hee; Gómez, Michael Andrés Abril; Salvato, Stéphanie Steiner; da Silva, Larissa Vitória; Costa, Elis Regina Dalla; et al. "Genomic-based surveillance reveals high ongoing transmission of multi-drug-resistant Mycobacterium tuberculosis in Southern Brazil". (2021): http://hdl.handle.net/10362/133338.
    https://doi.org/10.1016/j.ijantimicag.2021.106401
  24. Schön, Thomas; Werngren, Jim; Machado, Diana; Borroni, Emanuele; Wijkander, Maria; Lina, Gerard; Mouton, Johan; et al. "Multicentre testing of the EUCAST broth microdilution reference method for MIC determination on Mycobacterium tuberculosis". Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases (2021): http://hdl.handle.net/10362/116505.
    https://doi.org/10.1016/j.cmi.2020.10.019
  25. Tatiana Tozar; Sofia Santos Costa; Ana Maria Udrea; Viorel Nastasa; Isabel Couto; Miguel Viveiros; Mihail Lucian Pascu; et al. "Anti-staphylococcal activity and mode of action of thioridazine photoproducts". Scientific Reports Vol. 10 n.º 1 (2020): 18043-18055. https://novaresearch.unl.pt/en/publications/7f6bf3c7-512d-4cc3-b0e3-b9942d360c3a.
    10.1038/s41598-020-74752-z
  26. Viveiros, Miguel; Perdigão, João; Gomes, Pedro; Miranda, Anabela; Maltez, Fernando; Machado, Diana; Silva, Carla; et al. "Using genomics to understand the origin and dispersion of multidrug and extensively drug resistant tuberculosis in Portugal". Scientific Reports (2020): http://dx.doi.org/10.1038/s41598-020-59558-3.
    10.1038/s41598-020-59558-3
  27. João Perdigão; Carla Quintão; Fernando Maltez; Diana Machado; Anabela Miranda; Isabel Couto; Paulo Rabna; et al. "Emergence of multidrug-resistant Mycobacterium tuberculosis of the Beijing lineage in Portugal and Guinea-Bissau: a snapshot of moving clones by whole-genome sequencing". Emerging microbes & infections Vol. 9 n.º 1 (2020): 1342-1353. https://novaresearch.unl.pt/en/publications/997d4a3c-12af-4798-9249-b96d29a2d325.
    10.1080/22221751.2020.1774425
  28. Verza M; Scheffer MC; Salvato RS; Schorner MA; Barazzetti FH; de Melo Machado H; Medeiros TF; et al. "Author Correction: Genomic epidemiology of Mycobacterium tuberculosis in Santa Catarina, Southern Brazil.". Scientific reports (2020): http://europepmc.org/abstract/med/33139782.
    10.1038/s41598-020-76386-7
  29. Frédéric Méchaï; Hugues Cordel; Lorenzo Guglielmetti; Alexandra Aubry; Mateja Jankovic; Miguel Viveiros; Miguel Santin; et al. "Management of Tuberculosis". Frontiers in public health 8 (2020): https://novaresearch.unl.pt/en/publications/cfe4d982-d6f5-455e-9a1f-91cd5f580ec8.
    10.3389/fpubh.2020.00443
  30. Tavares A; Pingarilho M; Batista J; Viveiros M; Dias S; Toscano C; Gomes P; Abecasis AB. "HIV and tuberculosis co-infection among migrants in Portugal: a brief study on their sociodemographic, clinical, and genomic characteristics.". AIDS research and human retroviruses (2020): http://europepmc.org/abstract/med/32962419.
    10.1089/aid.2020.0119
  31. Thomas Schön; Jim Werngren; Diana Machado; Emanuele Borroni; Maria Wijkander; Gerard Lina; Johan Mouton; et al. "Antimicrobial susceptibility testing of Mycobacterium tuberculosis complex isolates". Clin. Microbiol. Infect Supl. 1198 n.º 20 (2020): 30444-30465. https://novaresearch.unl.pt/en/publications/6058800c-bdc4-464b-9cba-9edb82ab1942.
    10.1016/j.cmi.2020.07.036.
  32. Schön T; Köser CU; Werngren J; Viveiros M; Georghiou S; Kahlmeter G; Giske C; et al. "What is the role of the EUCAST reference method for MIC testing of the Mycobacterium tuberculosis complex?". Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases (2020): http://europepmc.org/abstract/med/32768492.
    10.1016/j.cmi.2020.07.037
  33. Min Ong CW; Migliori GB; Raviglione M; MacGregor-Skinner G; Sotgiu G; Alffenaar JW; Tiberi S; et al. "Epidemic and pandemic viral infections: impact on tuberculosis and the lung. A consensus by the World Association for Infectious Diseases and Immunological Disorders (WAidid), Global Tuberculosis Network (GTN) and members# of ESCMID Study Group for Mycobacterial Infections (ESGMYC).". The European respiratory journal (2020): http://europepmc.org/abstract/med/32586885.
    10.1183/13993003.01727-2020
  34. Verza M; Scheffer MC; Salvato RS; Schorner MA; Barazzetti FH; Machado HM; Medeiros TF; et al. "Genomic epidemiology of Mycobacterium tuberculosis in Santa Catarina, Southern Brazil.". Scientific reports (2020): http://europepmc.org/abstract/med/32732910.
    10.1038/s41598-020-69755-9
  35. Liliana Rodrigues; Pedro Cravo; Miguel Viveiros. "Efflux pump inhibitors as a promising adjunct therapy against drug resistant tuberculosis: a new strategy to revisit mycobacterial targets and repurpose old drugs". Expert Review of Anti-infective Therapy (2020): https://doi.org/10.1080/14787210.2020.1760845.
    10.1080/14787210.2020.1760845
  36. Bruno C. Gomes; Mónica Honrado; Ana Armada; Miguel Viveiros; José Rueff; António S. Rodrigues. "ABC Efflux Transporters and the Circuitry of miRNAs: Kinetics of Expression in Cancer Drug Resistance". International Journal of Molecular Sciences (2020): https://doi.org/10.3390/ijms21082985.
    10.3390/ijms21082985
  37. Richard Steiner Salvato; Elis Regina Dalla Costa; Ana Júlia Reis; Sun Hee Schiefelbein; Maria Laura Halon; Regina Bones Barcellos; Gisela Unis; et al. "First insights into circulating XDR and pre-XDR Mycobacterium tuberculosis in Southern Brazil". Infection, Genetics and Evolution 78 (2020): 104127-104127. https://doi.org/10.1016/j.meegid.2019.104127.
    10.1016/j.meegid.2019.104127
  38. Neves CP; Costa AG; Safe IP; de Souza Brito A; Jesus JS; Kritski AL; Lacerda MVG; Viveiros M; Cordeiro-Santos M. "The role of mini-bronchoalveolar lavage fluid in the diagnosis of pulmonary tuberculosis in critically ill patients.". BMC Infectious Diseases (2020): http://europepmc.org/abstract/med/32188399.
    10.1186/s12879-020-04954-3
  39. Borsoi AF; Paz JD; Abbadi BL; Macchi FS; Sperotto N; Pissinate K; Rambo RS; et al. "Design, synthesis, and evaluation of new 2-(quinoline-4-yloxy)acetamide-based antituberculosis agents.". European journal of medicinal chemistry (2020): http://europepmc.org/abstract/med/32113048.
    10.1016/j.ejmech.2020.112179
  40. Méchaï F; Cordel H; Guglielmetti L; Aubry A; Jankovic M; Viveiros M; Santin M; Goletti D; Cambau E. "Management of Tuberculosis: Are the Practices Homogeneous in High-Income Countries?". Frontiers in public health (2020): http://europepmc.org/abstract/PMC/PMC7509453.
    10.3389/fpubh.2020.00443
  41. Silvana Miranda; Isabela Almeida; Maria Mansur; Lida Figueredo; Wânia Carvalho; João Hadaad; Jaciara Diniz; et al. "Detection of drug resistant Mycobacterium tuberculosis strains using Kit SIRE Nitratase". Brazilian Archives of Biology and Technology Vol. 63 (2020): e20190179-e20190188. https://novaresearch.unl.pt/en/publications/4fc5a85d-c2bb-48da-9b8d-9da720ec66a6.
    https://doi.org/10.1590/1678-4324-2020190179
  42. Silvana Spindola de Miranda; Isabela Neves de Almeida; Maria de Fátima Filardi Oliveira Mansur; Lida Jouca de Assis Figueredo; Wânia da Silva Carvalho; João Paulo Amaral Hadaad; Jaciara de Lourdes do Carmo Guimarães Diniz; et al. "Detection of drug resistant mycobacterium tuberculosis strains using kit SIRE nitratase®". Brazilian Archives Of Biology And Technology 63 (2020): 1-9. https://novaresearch.unl.pt/en/publications/04f7768b-3da4-43d5-8514-9a45c7059216.
    10.1590/1678-4324-2020190179
  43. Gomes, Bruno C.; Honrado, Mónica; Armada, Ana; Viveiros, Miguel; Rueff, José; Rodrigues, António S.. "ABC Efflux Transporters and the Circuitry of miRNAs". (2020): http://hdl.handle.net/10362/97345.
    10.3390/ijms21082985Scopus
  44. Santos, Tânia Raquel Martins dos Martins dos. "Novel Therapeutic Strategies for the Management of Diabetic Foot Infections : the Evaluation of Selected Antimicrobial Peptides Against Clinically Isolated Bacterial Pathogens". Universidade de Lisboa (Portugal) (2020): https://publons.com/wos-op/publon/64843842/.
  45. Verza, Mirela; Scheffer, Mara Cristina; Salvato, Richard Steiner; Schorner, Marcos André; Barazzetti, Fernando Hartmann; Machado, Hanalydia de Melo; Medeiros, Taiane Freitas; et al. "Genomic epidemiology of Mycobacterium tuberculosis in Santa Catarina, Southern Brazil". (2020): http://hdl.handle.net/10362/116602.
    https://doi.org/10.1038/s41598-020-69755-9
  46. Miranda,Silvana Spindola de; Almeida,Isabela Neves de; Mansur,Maria de Fátima Filardi Oliveira; Figueredo,Lida Jouca de Assis; Carvalho,Wânia da Silva; Hadaad,João Paulo Amaral; Diniz,Jaciara de Lourdes do Carmo Guimarães; et al. "Detection of Drug Resistant Mycobacterium Tuberculosis Strains Using Kit SIRE Nitratase®: a Multicenter Study". (2020): http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132020000100308.
  47. Vieira ML; Liliana Rodrigues; Fernando Almeida; Filomeno Fortes; Sousa, Germano de; Monteiro, Sandra; Henrique Silveira; Miguel Viveiros. "O contributo dos serviços de diagnóstico laboratorial para o acesso universal à saúde nos países da Comunidade de Língua Portuguesa". Anais do Instituto de Higiene e Medicina Tropical Vol. 18 (2019): 42-51. https://novaresearch.unl.pt/en/publications/1b0e72c7-7520-4e49-a756-9d825609d611.
    https://doi.org/10.25761/anaisihmt.337
  48. Peter Brown; Aik-Choon Tan; Mohamed A. El-Esawi; Thomas Liehr; Oliver Blanck; Douglas P. Gladue; Gabriel M. F. Almeida; et al. "Large expert-curated database for benchmarking document similarity detection in biomedical literature search". DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION Vol. 2019 (2019): 1-66. https://novaresearch.unl.pt/en/publications/9a3d235f-7197-4ca3-b449-12d8b73c663e.
    10.1093/database/baz085
  49. Júlia S. Vianna; Diana Machado; Ivy B. Ramis; Fábia P. Silva; Dienefer V. Bierhals; Michael Andrés Abril; Andrea von Groll; et al. "The Contribution of Efflux Pumps in Mycobacterium abscessus Complex Resistance to Clarithromycin". Antibiotics (2019): https://doi.org/10.3390/antibiotics8030153.
    10.3390/antibiotics8030153
  50. Cá B; Fonseca KL; Sousa J; Maceiras AR; Machado D; Sanca L; Rabna P; et al. "Experimental Evidence for Limited in vivo Virulence of Mycobacterium africanum.". Frontiers in microbiology (2019): http://europepmc.org/abstract/med/31552007.
    10.3389/fmicb.2019.02102
  51. Tatara MB; Perdigão J; Viveiros M; Kritski A; Esther da Silva K; Correia Sacchi FP; Camioli de Lima C; Pereira Dos Santos PC; Andrade MKN. "Genetic Diversity and Molecular Epidemiology of Mycobacterium tuberculosis in Roraima State, Brazil.". The American journal of tropical medicine and hygiene (2019): http://europepmc.org/abstract/med/31392954.
    10.4269/ajtmh.19-0324
  52. Pena E; Machado D; Viveiros M; Jordão S. "A case report of disseminated Mycobacterium colombiense infection in an HIV patient.". International journal of mycobacteriology (2019): http://europepmc.org/abstract/med/31512608.
    10.4103/ijmy.ijmy_100_19
  53. Phelan JE; O'Sullivan DM; Machado D; Ramos J; Oppong YEA; Campino S; O'Grady J; et al. "Integrating informatics tools and portable sequencing technology for rapid detection of resistance to anti-tuberculous drugs.". Genome medicine (2019): http://europepmc.org/abstract/med/31234910.
    10.1186/s13073-019-0650-x
  54. Irene Rossi; Francesca Buttini; Fabio Sonvico; Filippo Affaticati; Francesco Martinelli; Giannamaria Annunziato; Diana Machado; et al. "Sodium Hyaluronate Nanocomposite Respirable Microparticles to Tackle Antibiotic Resistance with Potential Application in Treatment of Mycobacterial Pulmonary Infections". Pharmaceutics (2019): https://doi.org/10.3390/pharmaceutics11050203.
    10.3390/pharmaceutics11050203
  55. Tavares AM; Garcia AC; Gama A; Abecasis AB; Viveiros M; Dias S. "Tuberculosis care for migrant patients in Portugal: a mixed methods study with primary healthcare providers.". BMC health services research (2019): http://europepmc.org/abstract/med/30999913.
    10.1186/s12913-019-4050-0
  56. Felicetti T; Machado D; Cannalire R; Astolfi A; Massari S; Tabarrini O; Manfroni G; et al. "Modifications on C6 and C7 positions of 3-phenylquinolone efflux pump inhibitors led to potent and safe anti-mycobacterial treatment adjuvants.". ACS infectious diseases (2019): http://europepmc.org/abstract/med/30907573.
    10.1021/acsinfecdis.9b00041
  57. Catarina Pereira; Pedro Gomes; Ricardo Taveira; Carla Silva; Fernando Maltez; Rita Macedo; Catarina Costa; et al. "Insights on the Mycobacterium tuberculosis population structure associated with migrants from Portuguese-speaking countries over a three-year period in greater Lisbon, Portugal: Implications at the public health level". Infection, Genetics and Evolution (2019): https://doi.org/10.1016/j.meegid.2019.03.025.
    10.1016/j.meegid.2019.03.025
  58. Oppong YEA; Phelan J; Perdigão J; Machado D; Miranda A; Portugal I; Viveiros M; Clark TG; Hibberd ML. "Genome-wide analysis of Mycobacterium tuberculosis polymorphisms reveals lineage-specific associations with drug resistance.". BMC genomics (2019): http://europepmc.org/abstract/med/30922221.
    10.1186/s12864-019-5615-3
  59. Bouceiro-Mendes R; Ortins-Pina A; Fraga A; Marques T; Viveiros M; Machado D; Soares-de-Almeida L; Freitas JP; Filipe P. "Mycobacterium marinum lymphocutaneous infection.". Dermatology online journal (2019): http://europepmc.org/abstract/med/30865411.
  60. Júlia S. Vianna; Ivy B. Ramis; Dienefer Bierhals; Andrea von Groll; Daniela F. Ramos; Nilo Zanatta; Maria Cristina Lourenço; Miguel Viveiros; Pedro E.Almeida da Silva. "Tetrahydropyridine derivative as efflux inhibitor in Mycobacterium abscessus". Journal of Global Antimicrobial Resistance (2019): https://doi.org/10.1016/j.jgar.2018.12.020.
    10.1016/j.jgar.2018.12.020
  61. Ramis, I.B.; Vianna, J.S.; Silva Junior, L.; von Groll, A.; Ramos, D.F.; Zanatta, N.; Viveiros, M.; Silva, P.E.A.D.. "In silico and in vitro evaluation of tetrahydropyridine compounds as efflux inhibitors in Mycobacterium abscessus". Tuberculosis 118 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85069975225&partnerID=MN8TOARS.
    10.1016/j.tube.2019.07.004
  62. Viveiros, Miguel; Armada, Ana; Gomes, Bruno Costa; Viveiros, Miguel; Rueff, José; Rodrigues, António Sebastião; Instituto de Higiene e Medicina Tropical (IHMT); et al. "Regulation of ABCB1 activity by microRNA-200c and microRNA-203a in breast cancer cells: the quest for microRNAs’ involvement in cancer drug resistance". Cancer Drug Resistance (2019): http://dx.doi.org/10.20517/cdr.2019.24.
    10.20517/cdr.2019.24
  63. Vieira, Marisa Luísa; Rodrigues, Liliana; Almeida, Fernando; Fortes, Filomeno; de Sousa, Germano; Monteiro, Sandra; Silveira, Henrique; Viveiros, Miguel. "Laboratory services contribution to supporting public health and health services in Portuguese-speaking countries". (2019): http://anaisihmt.com/index.php/ihmt/article/view/337.
  64. R. Bouceiro-Mendes; A. Ortins-Pina; T. Marques; Miguel Viveiros; Diana Machado; L. Lito; J. Ferreira; et al. "A case report of multibacillary leprosy presenting with multiple outbreaks of erythema nodosum leprosum". Journal of the Portuguese Society of Dermatology and Venereology 77 1 (2019): 67–72-67–72. https://novaresearch.unl.pt/en/publications/8a92e91f-1688-481c-99d7-06cd5bea0d22.
  65. Vianna, Júlia S.; Machado, Diana; Ramis, Ivy B.; Silva, Fábia P.; Bierhals, Dienefer V.; Abril, Michael Andrés; Groll, Andrea von; et al. "The Contribution of efflux pumps in Mycobacterium abscessus complex resistance to clarithromycin". (2019): https://www.arca.fiocruz.br/handle/icict/36952.
    10.3390/antibiotics8030153
  66. Phelan, Jody E.; O'Sullivan, Denise M.; Machado, Diana; Ramos, Jorge; Oppong, Yaa E.A.; Campino, Susana; O'Grady, Justin; et al. "Integrating informatics tools and portable sequencing technology for rapid detection of resistance to anti-tuberculous drugs". (2019): http://hdl.handle.net/10362/116711.
    https://doi.org/10.1186/s13073-019-0650-x
  67. Santos Costa, Sofia; Sobkowiak, Benjamin; Parreira, Ricardo; Edgeworth, Jonathan D.; Viveiros, Miguel; Clark, Taane G.; Couto, Isabel; et al. "Genetic Diversity of norA, Coding for a Main Efflux Pump of Staphylococcus aureus". Frontiers in Genetics 9 (2019): http://hdl.handle.net/10362/116697.
    https://doi.org/10.3389/fgene.2018.00710
  68. Tavares, Ana Maria; Garcia, Ana Cristina; Gama, Ana; Abecasis, Ana B; Viveiros, Miguel; Dias, Sónia. "Tuberculosis care for migrant patients in Portugal". (2019): http://hdl.handle.net/10362/116708.
    https://doi.org/10.1186/s12913-019-4050-0
  69. Oppong, Yaa E. A.; Phelan, Jody; Perdigao, Joao; Machado, Diana; Miranda, Anabela; Portugal, Isabel; Viveiros, Miguel; Clark, Taane G.; Hibberd, Martin L.. "Genome-wide analysis of Mycobacterium tuberculosis polymorphisms reveals lineage-specific associations with drug resistance". (2019): http://hdl.handle.net/10362/116707.
    https://doi.org/10.1186/s12864-019-5615-3
  70. Diana Machado; Isabel Couto; Miguel Viveiros. "Advances in the molecular diagnosis of tuberculosis: From probes to genomes". Infection, Genetics and Evolution (2018): https://doi.org/10.1016/j.meegid.2018.11.021.
    10.1016/j.meegid.2018.11.021
  71. Alexandra S Simões; M. R. Maia; J. Gregorio; Isabel Couto; A. M. Asfeldt; G. S. Simonsen; Pedro Povoa; Miguel Viveiros; Luís Velez Lapão. "Participatory implementation of an antibiotic stewardship programme supported by an innovative surveillance and clinical decision-support system". Journal of Hospital Infection 100 3 (2018): 257-264. https://research.unl.pt/en/publications/participatory-implementation-of-an-antibiotic-stewardship-programme-supported-by-an-innovative-surveillance-and-clinical-decisionsupport-system(1b84098f-0e69-4114-b624-d8daea97b98c).html.
    10.1016/j.jhin.2018.07.034
  72. Luís Velez Lapão; Mélanie R. Maia; João Gregório; Isabel Couto; Pedro Povoa; Miguel Viveiros; Velez Lapao, L; et al. "Innovative Implementation of Antibiotic Stewardship supported by a Clinical Decision System". The European Journal of Public Health Vol. 28 supl. 4 (2018): 1-1. https://unl.elsevierpure.com/en/publications/3826e005-e0de-451d-b49a-e4bfb3322d20.
    10.1093/eurpub/cky213.547
  73. Diana Machado; Elisa Azzali; Isabel Couto; Gabriele Costantino; Marco Pieroni; Miguel Viveiros. "Adjuvant therapies against tuberculosis". Future Microbiology (2018): https://research.unl.pt/en/publications/adjuvant-therapies-against-tuberculosis(964db813-d647-41d0-a89c-258bcddf0314).html.
    10.2217/fmb-2018-0110
  74. Benjamin Sobkowiak; Judith R. Glynn; Rein M.G.J. Houben; Kim Mallard; Jody E. Phelan; José Afonso Guerra-Assunção; Louis Banda; et al. "Identifying mixed Mycobacterium tuberculosis infections from whole genome sequence data". BMC Genomics 19 1 (2018): https://research.unl.pt/en/publications/identifying-mixed-mycobacterium-tuberculosis-infections-from-whole-genome-sequence-data(5a159068-38b7-4eea-bdec-dd88c0baad60).html.
    10.1186/s12864-018-4988-z
  75. Moisés Francisco; Sofia Santos Costa; Adriana Belas; Jorge Ramos; Isabel Couto; Constança Pomba; Miguel Viveiros. "First report on antimicrobial resistance and molecular characterisation of Salmonella enterica serotype Typhi isolated from human specimens in Luanda, Angola". Journal of Global Antimicrobial Resistance 13 (2018): 246-249. https://doi.org/10.1016/j.jgar.2018.02.001.
    10.1016/j.jgar.2018.02.001
  76. Ramis IB; Vianna JS; Reis AJ; von Groll A; Ramos DF; Viveiros M; da Silva PEA. "Antimicrobial and Efflux Inhibitor Activity of Usnic Acid Against Mycobacterium abscessus.". Planta medica (2018): http://europepmc.org/abstract/med/29913527.
    10.1055/a-0639-5412
  77. Machado D; Antunes J; Simões A; Perdigão J; Couto I; McCusker M; Martins M; et al. "Contribution of efflux to colistin heteroresistance in a multidrug resistant Acinetobacter baumannii clinical isolate.". Journal of medical microbiology (2018): http://europepmc.org/abstract/med/29717972.
    10.1099/jmm.0.000741
  78. A. Tavares; A. Garcia; Abecasis AB; Miguel Viveiros; Sónia Dias. "Perspectives of health care providers in Portugal on the provision of care to migrant patients with TB or HIV-TB co-infection". European Journal of Public Health 28 (2018): 161-161. https://unl.elsevierpure.com/en/publications/88ef6e8e-51ed-4d48-a721-1c0950454fa7.
    doi.org/10.1093/eurpub/cky048.151
  79. Coll F; Phelan J; Hill-Cawthorne GA; Nair MB; Mallard K; Ali S; Abdallah AM; et al. "Author Correction: Genome-wide analysis of multi- and extensively drug-resistant Mycobacterium tuberculosis.". Nature genetics (2018): http://europepmc.org/abstract/med/29674744.
    10.1038/s41588-018-0074-3
  80. Deveson Lucas D; Crane B; Wright A; Han ML; Moffatt J; Bulach D; Gladman SL; et al. "Emergence of high-level colistin resistance in an Acinetobacter baumannii clinical isolate mediated by inactivation of the global regulator H-NS.". Antimicrobial agents and chemotherapy (2018): http://europepmc.org/abstract/med/29712662.
    10.1128/aac.02442-17
  81. Diana Machado; João Perdigão; Isabel Portugal; Marco Pieroni; Pedro Silva; Isabel Couto; Miguel Viveiros. "Efflux Activity Differentially Modulates the Levels of Isoniazid and Rifampicin Resistance among Multidrug Resistant and Monoresistant Mycobacterium tuberculosis Strains". Antibiotics 7 1 (2018): 18-18. https://doi.org/10.3390/antibiotics7010018.
    10.3390/antibiotics7010018
  82. Perdigão J; Silva C; Diniz J; Pereira C; Machado D; Ramos J; Silva H; et al. "Clonal expansion across the seas as seen through CPLP-TB database: A joint effort in cataloguing Mycobacterium tuberculosis genetic diversity in Portuguese-speaking countries.". Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases (2018): http://europepmc.org/abstract/med/29559379.
    10.1016/j.meegid.2018.03.011
  83. Francesc Coll; Jody Phelan; Grant A Hill-Cawthorne; Mridul B Nair; Kim Mallard; Shahjahan Ali; Abdallah M Abdallah; et al. "Genome-wide analysis of multi- and extensively drug-resistant Mycobacterium tuberculosis". Nature Genetics 50 2 (2018): 307-316. https://research.unl.pt/en/publications/genomewide-analysis-of-multi-and-extensively-drugresistant-mycobacterium-tuberculosis(08c685f9-703c-4b58-a15c-79a4cd7ec5d0).html.
    10.1038/s41588-017-0029-0
  84. Phelan J; de Sessions PF; Tientcheu L; Perdigao J; Machado D; Hasan R; Hasan Z; et al. "Methylation in Mycobacterium tuberculosis is lineage specific with associated mutations present globally.". Scientific reports (2018): http://europepmc.org/abstract/med/29317751.
    10.1038/s41598-017-18188-y
  85. Simões AS; Alves DA; Gregório J; Couto I; Dias S; Póvoa P; Viveiros M; Gonçalves L; Lapão LV. "Fighting antibiotic resistance in Portuguese Hospitals: understanding antibiotic prescription behaviors to better design antibiotic stewardship programs.". Journal of global antimicrobial resistance (2018): http://europepmc.org/abstract/med/29409949.
    10.1016/j.jgar.2018.01.013
  86. Costa, SS; Viveiros, M; Pomba, C; Couto, I. "Active antimicrobial efflux in Staphylococcus epidermidis: building up of resistance to fluoroquinolones and biocides in a major opportunistic pathogen". JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2018):
    10.1093/jac/dkx400
  87. Machado, D; Lecorche, E; Mougari, F; Cambau, E; Viveiros, M; Machado, Diana; Lecorche, Emmanuel; et al. "Insights on Mycobacterium leprae Efflux Pumps and Their Implications in Drug Resistance and Virulence". FRONTIERS IN MICROBIOLOGY (2018): http://hdl.handle.net/10362/116694.
    10.3389/fmicb.2018.03072
  88. Brynildsrud, OB; Pepperell, CS; Suffys, P; Grandjean, L; Monteserin, J; Debech, N; Bohlin, J; et al. "Global expansion of Mycobacterium tuberculosis lineage 4 shaped by colonial migration and local adaptation". SCIENCE ADVANCES (2018):
    10.1126/sciadv.aat5869
  89. Sobkowiak, Benjamin; Glynn, Judith R.; Houben, Rein M.G.J.; Mallard, Kim; Phelan, Jody E.; Guerra-Assunção, José Afonso; Banda, Louis; et al. "Identifying mixed Mycobacterium tuberculosis infections from whole genome sequence data". (2018): http://hdl.handle.net/10362/116846.
    https://doi.org/10.1186/s12864-018-4988-z
  90. Brynildsrud, Ola B.; Pepperell, Caitlin S.; Suffys, Philip; Grandjean, Louis; Monteserin, Johana; Debech, Nadia; Bohlin, Jon; et al. "Global expansion of Mycobacterium tuberculosis lineage 4 shaped by colonial migration and local adaptation". (2018): http://hdl.handle.net/10362/116688.
    https://doi.org/10.1126/sciadv.aat5869
  91. Phelan, Jody; De Sessions, Paola Florez; Tientcheu, Leopold; Perdigao, Joao; Machado, Diana; Hasan, Rumina; Hasan, Zahra; et al. "Methylation in Mycobacterium tuberculosis is lineage specific with associated mutations present globally". (2018): http://hdl.handle.net/10362/116703.
    https://doi.org/10.1038/s41598-017-18188-y
  92. Viveiros, Miguel; Matos, Olga; Conceição, Cláudia; Cruz, Deolinda; Rosado Pinto, José. "4th National Congress of Tropical Medicine and 1st Lusophone Meeting on AIDS, Tuberculosis and Opportunistic Diseases". The Institute of Hygiene and Tropical Medicine in Lisbon (IHMT) and the Association for the Development of Tropical Medicine (ADMT) organized the 4th National Congress of Tropical Medicine (CNMT) on April 19-21, 2017 in Lisbon in tandem with the 1st Lusophone Meeting on AIDS, Tuberculosis and Opportunistic Diseases, integrating the 115th anniversary of the IHMT. This biennial event brought togethe (2018): https://doi.org/10.25761/anaisihmt.20.
    https://doi.org/10.25761/anaisihmt.20
  93. Castro, Rita; Costa, João; Couto, Isabel; Vieira, Maria Luísa; Viveiros, Miguel; Rita Castro; J Costa; et al. "INFEÇÕES BACTERIANAS NEGLIGENCIADAS, ESQUECIDAS OU DESCONHECIDAS? A TRADIÇÃO EXÓTICA DO IHMT". . 11 (2018): https://doi.org/10.25761/anaisihmt.212.
    https://doi.org/10.25761/anaisihmt.212
  94. Viveiros, Miguel. "O ENSINO DAS CIÊNCIAS MÉDICAS E BIOMÉDICAS NO INSTITUTO DE HIGIENE E MEDICINA TROPICAL – A CONTEXTUALIZAÇÃO HISTÓRICO-PEDAGÓGICO". . (2018): https://doi.org/10.25761/anaisihmt.233.
    https://doi.org/10.25761/anaisihmt.233
  95. Viveiros, Miguel. "Activity of rifabutin and hemi-synthetic derivatives against Mycobacterium abscessus.". Medicinal chemistry (Shariqah (United Arab Emirates)) (2017): http://europepmc.org/abstract/med/29205119.
    10.2174/1573406414666171204102633
  96. Rolando Cannalire; Diana Machado; Tommaso Felicetti; Sofia Santos Costa; Serena Massari; Giuseppe Manfroni; Maria Letizia Barreca; et al. "Natural isoflavone biochanin A as a template for the design of new and potent 3-phenylquinolone efflux inhibitors against Mycobacterium avium". European Journal of Medicinal Chemistry 140 (2017): 321-330. https://research.unl.pt/en/publications/natural-isoflavone-biochanin-a-as-a-template-for-the-design-of-new-and-potent-3phenylquinolone-efflux-inhibitors-against-mycobacterium-avium(671a32ce-545c-4997-a030-d79c019e8eba).html.
    10.1016/j.ejmech.2017.09.014
  97. Diogo Vila-Viçosa; Bruno L Victor; Jorge Ramos; Diana Machado; Miguel Viveiros; Jacek Switala; Peter C Loewen; et al. "Insights on the mechanism of action of INH-C10 as an antitubercular prodrug". Molecular pharmaceutics 14 12 (2017): https://research.unl.pt/en/publications/insights-on-the-mechanism-of-action-of-inhc10-as-an-antitubercular-prodrug(88307fd0-7d81-4ff4-b5ef-52ab3a17134d).html.
    10.1021/acs.molpharmaceut.7b00719
  98. Yoshio Nakatani; Helen K Opel-Reading; Matthias Merker; Diana Machado; Sönke Andres; S Siva Kumar; Danesh Moradigaravand; et al. "Role of alanine racemase mutations in Mycobacterium tuberculosis D-cycloserine resistance". Antimicrobial Agents and Chemotherapy 61 12 (2017): https://research.unl.pt/en/publications/role-of-alanine-racemase-mutations-in-mycobacterium-tuberculosis-dcycloserine-resistance(ba3b15cd-2ab2-4c72-981d-1f70b4d99862).html.
    10.1128/AAC.01575-17
  99. Tavares, Ana Maria; Fronteira, Inês; Couto, Isabel; Machado, Diana; Viveiros, Miguel; Abecasis, Ana B.; Dias, Sónia; et al. "HIV and tuberculosis co-infection among migrants in Europe: A systematic review on the prevalence, incidence and mortality". PLOS ONE 12 9 (2017): e0185526. http://dx.doi.org/10.1371/journal.pone.0185526.
    10.1371/journal.pone.0185526
  100. Elisa Azzali; Diana Machado; Amit Kaushik; Federica Vacondio; Sara Flisi; Clotilde Silvia Cabassi; Gyanu Lamichhane; et al. "Substituted N-Phenyl-5-(2-(phenylamino)thiazol-4-yl)isoxazole-3-carboxamides Are Valuable Antitubercular Candidates that Evade Innate Efflux Machinery". Journal Of Medicinal Chemistry (2017): 7108-7108. https://research.unl.pt/en/publications/substituted-nphenyl52phenylaminothiazol4ylisoxazole3carboxamides-are-valuable-antitubercular-candidates-that-evade-innate-efflux-machinery(897491b3-e688-47ad-8a5f-a8d8261f676a).html.
    10.1021/acs.jmedchem.7b00793
  101. Viveiros, Miguel. "Detection of tuberculosis drug resistance: a comparison by Mycobacterium tuberculosis MLPA assay versus Genotype®MTBDRplus.". Memorias do Instituto Oswaldo Cruz (2017): http://europepmc.org/abstract/med/28591399.
    10.1590/0074-02760160376
  102. Schön, T.; Miotto, P.; Köser, C.U.; Viveiros, M.; Böttger, E.; Cambau, E.. "Mycobacterium tuberculosis drug-resistance testing: challenges, recent developments and perspectives". Clinical Microbiology and Infection 23 3 (2017): 154-160. http://dx.doi.org/10.1016/j.cmi.2016.10.022.
    10.1016/j.cmi.2016.10.022
  103. Guerreiro, Cátia Sá; Hartz, Zulmira; Sambo, Luís; Conceição, Cláudia; Dussault, Gilles; Russo, Giuliano; Viveiros, Miguel; et al. "Política de Investigação Científica para a Saúde em Portugal: II – Factos e Sugestões". Acta Médica Portuguesa 30 3 (2017): 233. http://dx.doi.org/10.20344/amp.8012.
    10.20344/amp.8012
  104. Sá Guerreiro, Cátia; Hartz, Zulmira; Sambo, Luís; Conceição, Cláudia; Dussault, Gilles; Russo, Giuliano; Viveiros, Miguel; et al. "Política de Investigação Científica para a Saúde em Portugal: I - Enquadramento Europeu e Nacional". Acta Médica Portuguesa 30 2 (2017): 141. http://dx.doi.org/10.20344/amp.8011.
    10.20344/amp.8011
  105. João Perdigão; Sofia Clemente; Jorge Ramos; Pedro Masakidi; Diana Machado; Carla Silva; Isabel Couto; et al. "Genetic diversity, transmission dynamics and drug resistance of Mycobacterium tuberculosis in Angola". Scientific Reports 7 1 (2017): 42814-42814. https://research.unl.pt/en/publications/genetic-diversity-transmission-dynamics-and-drug-resistance-of-mycobacterium-tuberculosis-in-angola(cba65502-3f10-4de0-b2cf-7b06d66c9450).html.
    10.1038/srep42814
  106. Ana Soares; Mónica S Estevão; M. Manuel B. Marques; Vasily Kovalishyn; Diogo A R S Latino; Joao Aires-de-Sousa; Jorge Ramos; Miguel Viveiros; Filomena Martins. "Synthesis and Biological Evaluation of Hybrid 1,5- and 2,5-Disubstituted Indoles as Potentially New Antitubercular Agents". Journal Of Medicinal Chemistry 13 5 (2017): 439-439. https://research.unl.pt/en/publications/synthesis-and-biological-evaluation-of-hybrid-15-and-25disubstituted-indoles-as-potentially-new-antitubercular-agents(b8ab96c2-2ef3-46d9-ad19-4d948f399fa3).html.
    10.2174/1573406413666170209144003
  107. Bettencourt, Miguel. "Thioridazine: A Non-Antibiotic Drug Highly Effective, in Combination with First Line Anti-Tuberculosis Drugs, against Any Form of Antibiotic Resistance of Mycobacterium tuberculosis Due to Its Multi-Mechanisms of Action". Antibiotics (2017): http://www.mdpi.com/2079-6382/6/1/3.
    10.3390/antibiotics6010003
  108. Silva L; Carrion LL; von Groll A; Costa SS; Junqueir E; Ramos DF; Cantos J; et al. "In vitro and in silico analysis of the efficiency of tetrahydropyridines as drug efflux inhibitors in Escherichia coli.". International Journal of Antimicrobial Agents 49 3 (2017): 1-3. http://europepmc.org/abstract/med/28153476.
    10.1016/j.ijantimicag.2016.11.024
  109. Diana Machado; Tatiane S Coelho; João Perdigão; Catarina Pereira; Isabel Couto; Isabel Portugal; Raquel De Abreu Maschmann; et al. "Interplay between Mutations and Efflux in Drug Resistant Clinical Isolates of Mycobacterium tuberculosis". Frontiers in Microbiology 8 (2017): 711-711. https://research.unl.pt/en/publications/interplay-between-mutations-and-efflux-in-drug-resistant-clinical-isolates-of-mycobacterium-tuberculosis(26dcab5e-97f6-4c2b-a305-f0ece9e75609).html.
    10.3389/fmicb.2017.00711
  110. Sandra A. Morais; Virginia Moneti; Joana Silva; Karen Pereira; Marta Manso; Teresa Vilaça Santos; Vera Falcão; et al. "Tuberculose extensivamente resistente: uma realidade presente. Revisão da literatura a propósito de um caso clínico.". Revista Portuguesa de Doenças Infecciosas (2017): https://research.unl.pt/en/publications/tuberculose-extensivamente-resistente-uma-realidade-presente-revisao-da-literatura-a-proposito-de-um-caso-clinico(267c92fc-6bde-4450-9c3c-35a22f5b7ed7).html.
  111. Machado, D.; Fernandes, L.; Costa, S.S.; Cannalire, R.; Manfroni, G.; Tabarrini, O.; Couto, I.; et al. "Mode of action of the 2-phenylquinoline efflux inhibitor PQQ4R against Escherichia coli". PeerJ 2017 4 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85018654266&partnerID=MN8TOARS.
    10.7717/peerj.3168
  112. Nakatani, Yoshio; Opel-Reading, Helen K; Merker, Matthias; Machado, Diana; Andres, Sönke; Kumar, S Siva; Moradigaravand, Danesh; et al. "Role of alanine racemase mutations in Mycobacterium tuberculosis D-cycloserine resistance". (2017): http://hdl.handle.net/10362/32683.
    https://doi.org/10.1128/AAC.01575-17
  113. Sá Guerreiro, Cátia; Hartz, Zulmira; Sambo, Luís; Conceição, Cláudia; Dussault, Gilles; Russo, G; Viveiros, Miguel; et al. "Política de investigação científica para a saúde em Portugal". Acta Médica Portuguesa 30 3 (2017): 233-242. http://hdl.handle.net/10362/36435.
    https://doi.org/10.20344/amp.8012
  114. Viveiros, Miguel; Matos, Olga. "4º Congresso Nacional de Medicina Tropical (CNMT) e 1º Encontro Lusófono de Sida, Tuberculose e Doenças Oportunistas". (2017): http://hdl.handle.net/10362/116882.
    https://doi.org/10.25761/anaisihmt.20
  115. Conceição, Cláudia; Viveiros, Miguel; Cruz, Deolinda; Rosado Pinto, José. "4 º Congresso Nacional de Medicina Tropical". (2017): http://hdl.handle.net/10362/116883.
    https://doi.org/10.25761/anaisihmt.23
  116. Jody Phelan; Denise M. O'Sullivan; Diana Machado; Jorge Ramos; Alexandra S. Whale; Justin O'Grady; Keertan Dheda; et al. "The variability and reproducibility of whole genome sequencing technology for detecting resistance to anti-tuberculous drugs". Genome Medicine 8 1 (2016): https://research.unl.pt/en/publications/the-variability-and-reproducibility-of-whole-genome-sequencing-technology-for-detecting-resistance-to-antituberculous-drugs(9f7fd63d-cdfe-4848-8253-057aa8579cb0).html.
    10.1186/s13073-016-0385-x
  117. Sofia Santos Costa; Cláudia Palma; Kristina Kadlec; Andrea T. Fessler; Miguel Viveiros; José Melo-Cristino; Stefan Schwarz; Isabel Couto. "Plasmid-borne antimicrobial resistance of staphylococcus aureus isolated in a hospital in Lisbon, Portugal". Microbial Drug Resistance 22 8 (2016): 617-626. https://research.unl.pt/en/publications/plasmidborne-antimicrobial-resistance-of-staphylococcus-aureus-isolated-in-a-hospital-in-lisbon-portugal(c958cee5-7d8c-4cc6-ade6-34077b2064a3).html.
    10.1089/mdr.2015.0352
  118. J Perdigão; F Maltez; Diana Machado; H Silveira; C Pereira; C Silva; Isabel Couto; Miguel Viveiros; I Portugal. "Beyond extensively drug-resistant tuberculosis in Lisbon, Portugal". International Journal Of Antimicrobial Agents 48 5 (2016): 569-570. https://research.unl.pt/en/publications/beyond-extensively-drugresistant-tuberculosis-in-lisbon-portugal(90dceb78-989b-43ea-8b57-b2e1193e4979).html.
    10.1016/j.ijantimicag.2016.07.026
  119. Sofia Santos Costa; Elizeth Lopes; Elisa Azzali; Diana Machado; Tatiane Coelho; Pedro Eduardo Almeida Da Silva; Miguel Viveiros; Marco Pieroni; Isabel Couto. "An Experimental Model for the Rapid Screening of Compounds with Potential Use Against Mycobacteria". Assay and Drug Development Technologies 14 9 (2016): 524-534. https://research.unl.pt/en/publications/an-experimental-model-for-the-rapid-screening-of-compounds-with-potential-use-against-mycobacteria(49709c9e-e92e-4438-830b-60cd071815b5).html.
    10.1089/adt.2016.752
  120. Phelan, Jody E.; Coll, Francesc; Bergval, Indra; Anthony, Richard M.; Warren, Rob; Sampson, Samantha L.; Gey van Pittius, Nicolaas C.; et al. "Recombination in pe/ppe genes contributes to genetic variation in Mycobacterium tuberculosis lineages". BMC Genomics 17 1 (2016): http://dx.doi.org/10.1186/s12864-016-2467-y.
    10.1186/s12864-016-2467-y
  121. Simões, A.S.; Couto, I.; Toscano, C.; Gonçalves, E.; Póvoa, P.; Viveiros, M.; Lapão, L.V.. "Prevention and control of antimicrobial resistant healthcare-associated infections: The microbiology laboratory rocks!". Frontiers in Microbiology 7 JUN (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84976864101&partnerID=MN8TOARS.
    10.3389/fmicb.2016.00855
  122. Machado, D.; Cannalire, R.; Santos Costa, S.; Manfroni, G.; Tabarrini, O.; Cecchetti, V.; Couto, I.; Viveiros, M.; Sabatini, S.. "Boosting Effect of 2-Phenylquinoline Efflux Inhibitors in Combination with Macrolides against Mycobacterium smegmatis and Mycobacterium avium". ACS Infectious Diseases 1 12 (2016): 593-603. http://www.scopus.com/inward/record.url?eid=2-s2.0-84969256572&partnerID=MN8TOARS.
    10.1021/acsinfecdis.5b00052
  123. Phelan, Jody; O'Sullivan, Denise M.; Machado, Diana; Ramos, Jorge; Whale, Alexandra S.; O'Grady, Justin; Dheda, Keertan; et al. "The variability and reproducibility of whole genome sequencing technology for detecting resistance to anti-tuberculous drugs". (2016): http://www.scopus.com/inward/record.url?scp=85006757655&partnerID=8YFLogxK.
    https://doi.org/10.1186/s13073-016-0385-x
  124. Machado, Diana; Pires, David; Perdigão, João; Couto, Isabel; Portugal, Isabel; Martins, Marta; Amaral, Leonard; et al. "Ion channel blockers as antimicrobial agents, efflux inhibitors, and enhancers of macrophage killing activity against drug resistant mycobacterium tuberculosis". PLOS ONE 11 2 (2016): e0149326. http://www.scopus.com/inward/record.url?scp=84960338991&partnerID=8YFLogxK.
    https://doi.org/10.1371/journal.pone.0149326
  125. Miguel Viveiros; MJ Simões. "Pequena história da RIDES-Tuberculose no âmbito do Plano Estratégico de Cooperação em saúde 2009-2012 da Comunidade dos Países de Língua Portuguesa". Anais Do Instituto De Higiene E Medicina Tropical 15 1 (2016): 45-50. https://novaresearch.unl.pt/en/publications/2a9026d1-aa7a-4a77-b1fe-688ca351356d.
  126. de Matos, Ana Cristina Outeiro Correia Outeiro Correia. "New Insights on Zoonotic and Non-zoonotic Mycobacteriosis in Wild Mammals in Portugal: Epidemiological and Histopathological Aspects". Universidade de Tras-os-Montes E Alto Douro (Portugal) (2016): https://publons.com/wos-op/publon/64843843/.
  127. Elis R. Dalla Costa; Sidra E G Vasconcelos; Leonardo S. Esteves; Harrison M. Gomes; Lia L. Gomes; Pedro Almeida Da Silva; João Perdigão; et al. "Multidrug-resistant mycobacterium tuberculosis of the Latin American mediterranean lineage, wrongly identified as mycobacterium pinnipedii (Spoligotype International Type 863 [SIT863]), causing active tuberculosis in South Brazil". Journal Of Clinical Microbiology 53 12 (2015): 3805-3811. https://research.unl.pt/en/publications/multidrugresistant-mycobacterium-tuberculosis-of-the-latin-american-mediterranean-lineage-wrongly-identified-as-mycobacterium-pinnipedii-spoligotype-international-type-863-sit863-causing-active-tuber(3bcb74ef-5a7c-4.
    10.1128/JCM.02012-15
  128. Francesc Coll; Ruth McNerney; Mark D. Preston; José Afonso Guerra-Assunção; Andrew Warry; Grant Hill-Cawthorne; Kim Mallard; et al. "Rapid determination of anti-tuberculosis drug resistance from whole-genome sequences". Genome Medicine 7 1 (2015): https://research.unl.pt/en/publications/rapid-determination-of-antituberculosis-drug-resistance-from-wholegenome-sequences(d8f4e4e6-76c2-4f7c-bb4f-15e9c0e8e9ab).html.
    10.1186/s13073-015-0164-0
  129. Isabel Couto; Miguel Viveiros. "Breve história da micobacteriologia no IHMT/UNL". Anais do Instituto de Higiene e Medicina Tropical 13 (2015): 29-35. https://research.unl.pt/en/publications/breve-historia-da-micobacteriologia-no-ihmtunl(d4629590-1023-4e29-ba9a-a75c8b5341e3).html.
    https://doi.org/10.25761/anaisihmt.168
  130. Cambau, E.; Viveiros, M.; Machado, D.; Raskine, L.; Ritter, C.; Tortoli, E.; Matthys, V.; et al. "Revisiting susceptibility testing in MDR-TB by a standardized quantitative phenotypic assessment in a European multicentre study". Journal of Antimicrobial Chemotherapy 70 3 (2015): 686-696. http://www.scopus.com/inward/record.url?eid=2-s2.0-84928183832&partnerID=MN8TOARS.
    10.1093/jac/dku438
  131. Cabral, V.; Luo, X.; Junqueira, E.; Costa, S.S.; Mulhovo, S.; Duarte, A.; Couto, I.; Viveiros, M.; Ferreira, M.-J.U.. "Enhancing activity of antibiotics against Staphylococcus aureus: Zanthoxylum capense constituents and derivatives". Phytomedicine 22 4 (2015): 469-476. http://www.scopus.com/inward/record.url?eid=2-s2.0-84964270861&partnerID=MN8TOARS.
    10.1016/j.phymed.2015.02.003
  132. Pinto-Almeida, A.; Mendes, T.; Armada, A.; Belo, S.; Carrilho, E.; Viveiros, M.; Afonso, A.. "The role of efflux pumps in Schistosoma mansoni Praziquantel resistant phenotype". PLoS ONE 10 10 (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84948692444&partnerID=MN8TOARS.
    10.1371/journal.pone.0140147
  133. Coelho, T.; Machado, D.; Couto, I.; Maschmann, R.; Ramos, D.; Groll, A.; Rossetti, M.L.; Silva, P.A.; Viveiros, M.. "Enhancement of antibiotic activity by efflux inhibitors against multidrug resistant Mycobacterium tuberculosis clinical isolates from Brazil". Frontiers in Microbiology 6 APR (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84930941347&partnerID=MN8TOARS.
    10.3389/fmicb.2015.00330
  134. Perdigão, J.; Silva, H.; Machado, D.; Macedo, R.; Maltez, F.; Silva, C.; Jordao, L.; et al. "Genomic diversity of drug-resistant Mycobacterium tuberculosis isolates in Lisbon Portugal: Towards tuberculosis genomic epidemiology". International Journal of Mycobacteriology (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84921367931&partnerID=MN8TOARS.
    10.1016/j.ijmyco.2015.01.001
  135. Pinto-Almeida, António; Mendes, Tiago; Armada, Ana; Belo, Silvana; Carrilho, Emanuel; Viveiros, Miguel; Afonso, Ana; et al. "The role of efflux pumps in Schistosoma mansoni Praziquantel resistant phenotype". (2015): http://www.scopus.com/inward/record.url?scp=84948692444&partnerID=8YFLogxK.
    https://doi.org/10.1371/journal.pone.0140147
  136. Rabna, Paulo; Ramos, Jorge; Ponce, Gema; Sanca, Lilica; Mané, Morto; Armada, Ana; Machado, Diana; et al. "Direct detection by the xpert MTB/RIF assay and characterization of multi and poly drug- resistant tuberculosis in Guinea-Bissau, West Africa". PLOS ONE 10 5 (2015): e0127536. http://www.scopus.com/inward/record.url?scp=84958198245&partnerID=8YFLogxK.
    https://doi.org/10.1371/journal.pone.0127536
  137. Costa, Sofia Santos; Viveiros, Miguel; Rosato, Adriana E.; Melo-Cristino, José; Couto, Isabel; TB, HIV and opportunistic diseases and pathogens (THOP); Global Health and Tropical Medicine (GHTM); et al. "Impact of efflux in the development of multidrug resistance phenotypes in Staphylococcus aureus Clinical microbiology and vaccines". Bmc Microbiology 15 1 (2015): http://www.scopus.com/inward/record.url?scp=84945118570&partnerID=8YFLogxK.
    https://doi.org/10.1186/s12866-015-0572-8
  138. Coelho, Tatiane; Machado, Diana; Couto, Isabel; Maschmann, Raquel; Ramos, Daniela; Groll, Andrea von; Rossetti, Maria L.; et al. "Enhancement of antibiotic activity by efflux inhibitors against multidrug resistant Mycobacterium tuberculosis clinical isolates from Brazil". (2015): http://www.scopus.com/inward/record.url?scp=84930941347&partnerID=8YFLogxK.
    https://doi.org/10.3389/fmicb.2015.00330
  139. Dalla Costa, Elis R.; Vasconcelos, Sidra E G; Esteves, Leonardo S.; Gomes, Harrison M.; Gomes, Lia L.; Da Silva, Pedro Almeida; Perdigão, João; et al. "Multidrug-resistant mycobacterium tuberculosis of the Latin American mediterranean lineage, wrongly identified as mycobacterium pinnipedii (Spoligotype International Type 863 [SIT863]), causing active tuberculosis in South Brazil". (2015): http://www.scopus.com/inward/record.url?scp=84947775741&partnerID=8YFLogxK.
    https://doi.org/10.1128/JCM.02012-15
  140. Pieroni, M.; Machado, D.; Azzali, E.; Santos Costa, S.; Couto, I.; Costantino, G.; Viveiros, M.. "Rational Design and Synthesis of Thioridazine Analogues as Enhancers of the Antituberculosis Therapy". Journal of Medicinal Chemistry 58 15 (2015): 5842-5853. http://www.scopus.com/inward/record.url?eid=2-s2.0-84939125634&partnerID=MN8TOARS.
    10.1021/acs.jmedchem.5b00428
  141. Célia Leão; Ana Canto; Diana Machado; Ilda Santos Sanches; Isabel Couto; Miguel Viveiros; João Inácio; Ana Botelho. "Relatedness of Mycobacterium avium subspecies hominissuis clinical isolates of human and porcine origins assessed by MLVA". Veterinary Microbiology 173 1-2 (2014): 92-100. https://research.unl.pt/en/publications/relatedness-of-mycobacterium-avium-subspecies-hominissuis-clinical-isolates-of-human-and-porcine-origins-assessed-by-mlva(fbddaea4-ee1b-4a32-9b94-b0d2e8e6f1ca).html.
    10.1016/j.vetmic.2014.06.027
  142. Francesc Coll; Ruth McNerney; José Afonso Guerra-Assunção; Judith R. Glynn; João Perdigão; Miguel Viveiros; Isabel Portugal; et al. "A robust SNP barcode for typing Mycobacterium tuberculosis complex strains". NATURE COMMUNICATIONS 5 (2014): https://research.unl.pt/en/publications/a-robust-snp-barcode-for-typing-mycobacterium-tuberculosis-complex-strains(daca2113-5110-4d32-94f6-8415c90a70ac).html.
    10.1038/ncomms5812
  143. Pedro Pedrosa; Bruno Veigas; Diana Machado; Isabel Couto; Miguel Viveiros; P. V. Baptista. "Gold nanoprobes for multi loci assessment of multi-drug resistant tuberculosis". Tuberculosis 94 3 (2014): 332-337. https://research.unl.pt/en/publications/gold-nanoprobes-for-multi-loci-assessment-of-multidrug-resistant-tuberculosis(0e5dc7d1-023f-414e-8149-1ffb9ed75cba).html.
    10.1016/j.tube.2013.12.009
  144. Filomena Martins; Susana Santos; Cristina Ventura; Ruben Elvas-Leitão; Lidia Santos; Susana Vitorino; Marina Reis; et al. "Design, synthesis and biological evaluation of novel isoniazid derivatives with potent antitubercular activity.". European Journal Of Medicinal Chemistry 81C (2014): 119-138. https://research.unl.pt/en/publications/design-synthesis-and-biological-evaluation-of-novel-isoniazid-derivatives-with-potent-antitubercular-activity(c12c3c4a-6fc7-4143-9d65-725c51a2533f).html.
    10.1016/j.ejmech.2014.04.077
  145. Pedro Costa; Ana Botelho; Isabel Couto; Miguel Viveiros; João Inácio; Costa, Pedro; Botelho, Ana R.; et al. "Standing of nucleic acid testing strategies in veterinary diagnosis laboratories to uncover Mycobacterium tuberculosis complex members". Frontiers in molecular biosciences 15 1 (2014): 16-16. https://research.unl.pt/en/publications/standing-of-nucleic-acid-testing-strategies-in-veterinary-diagnosis-laboratories-to-uncover-mycobacterium-tuberculosis-complex-members(f6c6f080-d462-433b-a86f-6ef17abe995e).html.
    10.3389/fmolb.2014.00016
  146. Machado, D; Ramos, J; Couto, I; Cadir, N; Narciso, I; Coelho, E; Viegas, S; Viveiros, M. "Assessment of the BD MGIT TBc Identification Test for the Detection of Mycobacterium tuberculosis Complex in a Network of Mycobacteriology Laboratories". BIOMED RESEARCH INTERNATIONAL (2014):
    10.1155/2014/398108
  147. Francesc Coll; Mark Preston; José Afonso Guerra-Assunção; Grant Hill-Cawthorn; David Harris; João Perdigão; Miguel Viveiros; et al. "PolyTB". Tuberculosis (Edinburgh, Scotland) 94 3 (2014): 346-354. https://research.unl.pt/en/publications/polytb(f050e743-ad4f-4f57-8cc1-9fa7a3645962).html.
    10.1016/j.tube.2014.02.005
  148. Viveiros, M.; Pieroni, M.. "Spectinamides: A challenge, a proof, and a suggestion". Trends in Microbiology 22 4 (2014): 170-171. http://www.scopus.com/inward/record.url?eid=2-s2.0-84897434951&partnerID=MN8TOARS.
    10.1016/j.tim.2014.02.008
  149. Pedro Costa; Ana Amaro; Ana S. Ferreira; Diana Machado; Teresa Albuquerque; Isabel Couto; Ana Botelho; et al. "Rapid identification of veterinary-relevant Mycobacterium tuberculosis complex species using 16S rDNA, IS6110 and Regions of Differencetargeted dual-labelled hydrolysis probes". Journal Of Microbiological Methods 107 (2014): 13-22. https://research.unl.pt/en/publications/rapid-identification-of-veterinaryrelevant-mycobacterium-tuberculosis-complex-species-using-16s-rdna-is6110-and-regions-of-differencetargeted-duallabelled-hydrolysis-probes(beeda4f4-a0ab-496b-a9a0-f5eacea15679).html.
    10.1016/j.mimet.2014.08.017
  150. de Carvalho, C.C.C.R.; Costa, S.S.; Fernandes, P.; Couto, I.; Viveiros, M.; de Carvalho, Carla C C R; Costa, Sofia Maria Mourão Marques dos Santos; et al. "Membrane transport systems and the biodegradation potential and pathogenicity of genus Rhodococcus". Frontiers in Physiology 5 APR (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84901008267&partnerID=MN8TOARS.
    10.3389/fphys.2014.00133
  151. Perdigão, João; Silva, Hugo; Machado, Diana; Macedo, Rita; Maltez, Fernando; Silva, Carla; Jordão, Luísa; et al. "Unraveling Mycobacterium tuberculosis genomic diversity and evolution in Lisbon, Portugal, a highly drug resistant setting". Bmc Genomics 15 (2014): 991-991. http://hdl.handle.net/10400.18/2931.
    10.1186/1471-2164-15-991
  152. Martins, F.; Ventura, C.; Santos, S.; Viveiros, M.. "QSAR based design of new antitubercular compounds: Improved isoniazid derivatives against multidrug-resistant TB". Current Pharmaceutical Design 20 27 (2014): 4427-4454. http://www.scopus.com/inward/record.url?eid=2-s2.0-84904757088&partnerID=MN8TOARS.
    10.2174/1381612819666131118164434
  153. Coll, Francesc; McNerney, Ruth; Guerra-Assunção, José Afonso; Glynn, Judith R.; Perdigão, João; Viveiros, Miguel; Portugal, Isabel; et al. "A robust SNP barcode for typing Mycobacterium tuberculosis complex strains". (2014): http://hdl.handle.net/10362/116795.
    https://doi.org/10.1038/ncomms5812
  154. Machado, Diana; Ramos, Jorge; Couto, Isabel; Cadir, Nureisha; Narciso, Inácio; Coelho, Elizabeth; Viegas, Sofia; Viveiros, Miguel. "Assessment of the BD MGIT TBc identification test for the detection of mycobacterium tuberculosis complex in a network of mycobacteriology laboratories". (2014): http://hdl.handle.net/10362/116796.
    https://doi.org/10.1155/2014/398108
  155. Pedro Costa; Ana S. Ferreira; Ana Amaro; Teresa Albuquerque; Ana Botelho; Isabel Couto; Mónica V. Cunha; et al. "Enhanced detection of tuberculous mycobacteria in animal tissues using a semi-nested probe-based real-time PCR". PLoS ONE 8 11 (2013): https://research.unl.pt/en/publications/enhanced-detection-of-tuberculous-mycobacteria-in-animal-tissues-using-a-seminested-probebased-realtime-pcr(d55534de-59e0-49b4-ab32-2226ae5085a4).html.
    10.1371/journal.pone.0081337
  156. Ana Armada; Tatiana Alexandru; Diana Machado; Balazs Danko; Attila Hunyadi; Andra Dinache; Viorel Nastasa; et al. "The in vitro activity of products formed from exposure of chlorpromazine to a 266nm laser beam against species of mycobacteria of human interest". In vivo (Athens, Greece) 27 5 (2013): 605-610. https://research.unl.pt/en/publications/the-in-vitro-activity-of-products-formed-from-exposure-of-chlorpromazine-to-a-266nm-laser-beam-against-species-of-mycobacteria-of-human-interest(170bb203-57a9-4067-b045-3c8a91752d36).html.
  157. Sofia Santos Costa; Elisabete Junqueira; Cláudia Palma; Miguel Viveiros; José Melo-Cristino; Leonard Amaral; Isabel Couto. "Resistance to antimicrobials mediated by efflux pumps in Staphylococcus aureus". Antibiotics 2 1 (2013): 83-99. https://research.unl.pt/en/publications/resistance-to-antimicrobials-mediated-by-efflux-pumps-in-staphylococcus-aureus(c5ee046d-4c8e-4800-8548-3d7faf8f0b8c).html.
    10.3390/antibiotics2010083
  158. Ana Armada; Miguel Viveiros; Leonard Amaral. "Biological evaluation of products formed from the irradiation of chlorpromazine with a 266 nm laser beam.". Biochemistry & Pharmacology - Open Access 2 NA (2013): 109-109. https://research.unl.pt/en/publications/biological-evaluation-of-products-formed-from-the-irradiation-of-chlorpromazine-with-a-266-nm-laser-beam(e8ea1b38-bb33-4ea2-8ac5-8868b233d91b).html.
  159. J Perdigão; R., Macedo,; C., Silva,; Diana Machado; Isabel Couto; Miguel Viveiros; L., Jordao,; et al. "From multidrug-resistant to extensively drug-resistant tuberculosis in Lisbon, Portugal: the stepwise mode of resistance acquisition.". Journal of Antimicrobial Chemotherapy 68 1 (2013): 27-33. https://research.unl.pt/en/publications/from-multidrugresistant-to-extensively-drugresistant-tuberculosis-in-lisbon-portugal-the-stepwise-mode-of-resistance-acquisition(f70530b4-0075-4d58-8900-f431450e2874).html.
    10.1093/jac/dks371
  160. Abecasis AB; Miguel Viveiros; Leonard Amaral. "Activity of the efflux pump inhibitor SILA 421 against drug-resistant tuberculosis.". International Journal Of Antimicrobial Agents 41 5 (2013): 488-489. https://research.unl.pt/en/publications/activity-of-the-efflux-pump-inhibitor-sila-421-against-drugresistant-tuberculosis(45e829ee-e540-4800-bb87-d02985173041).html.
    10.1016/j.ijantimicag.2013.01.001
  161. Sofia Santos Costa; C., Mourato,; Miguel Viveiros; J., Melo- Cristino,; Leonard Amaral; Isabel Couto. "Description of plasmid pSM52, harbouring the gene for the Smr efflux pump, and its involvement in resistance to biocides in a meticillin-resistant Staphylococcus aureus strain.". International Journal Of Antimicrobial Agents 41 (2013): https://research.unl.pt/en/publications/description-of-plasmid-psm52-harbouring-the-gene-for-the-smr-efflux-pump-and-its-involvement-in-resistance-to-biocides-in-a-meticillinresistant-staphylococcus-aureus-strain(2b79dedb-fd6e-46a0-9aaa-a87bdd957d1c).html.
    10.1016/j.ijantimicag.2013.01.003
  162. Miguel Viveiros; Diana Machado; J Perdigão; J, Ramos; Isabel Couto; I, Portugal; C. Ritter; E.C., Boettger,. "High-level resistance to isoniazid and ethionamide in multidrug-resistant Mycobacterium tuberculosis of the Lisboa family is associated with inhA double mutations.". Journal of Antimicrobial Chemotherapy 68 8 (2013): 1728-32. https://research.unl.pt/en/publications/highlevel-resistance-to-isoniazid-and-ethionamide-in-multidrugresistant-mycobacterium-tuberculosis-of-the-lisboa-family-is-associated-with-inha-double-mutations(ee32cb8e-627a-43a1-ab9d-bb5a9a980d2c).html.
    10.1093/jac/dkt090
  163. Miguel Viveiros. "Role of the Mmr efflux pump in drug resistance in Mycobacterium tuberculosis.". Antimicrobial Agents And Chemotherapy 57 2 (2013): 751-7. https://research.unl.pt/en/publications/role-of-the-mmr-efflux-pump-in-drug-resistance-in-mycobacterium-tuberculosis(27f6e97f-ba86-469c-84fe-21722c84046c).html.
    10.1128/aac.01482-12
  164. P. V. Baptista; Miguel Viveiros; Isabel Couto. "Isothermal DNA amplification coupled to Aunanoprobes for detection of mutations associated to Rifampicin resistance in Mycobacterium tuberculosis". Journal Of Nanobiotechnology 11 NA (2013): 38-38. https://research.unl.pt/en/publications/isothermal-dna-amplification-coupled-to-aunanoprobes-for-detection-of-mutations-associated-to-rifampicin-resistance-in-mycobacterium-tuberculosis(c1384fed-4794-4633-8b01-bbe0c27aedb0).html.
    10.1186/1477-3155-11-38
  165. Leonard Amaral; Miguel Viveiros; Isabel Couto; Martins, Marta; McCusker, Matthew P.; Bettencourt, Miguel Viveiros; Couto, Isabel Maria dos Santos Leitão; et al. "A simple method for assessment of MDR bacteria for over-expressed efflux pumps.". Open Microbiology Journal 7 NA (2013): 72-82. https://research.unl.pt/en/publications/a-simple-method-for-assessment-of-mdr-bacteria-for-overexpressed-efflux-pumps(d873b843-79f0-490f-80b4-0ea7808a6f2f).html.
    10.2174/1874285801307010072
  166. Sofia Santos Costa; Miguel Viveiros; Leonard Amaral; Isabel Couto; Costa, SS; Bettencourt, Miguel Viveiros; Amaral, Leonard; Couto, Isabel Maria dos Santos Leitão. "Multidrug efflux pumps in Staphylococcus aureus: an update.". Open Microbiology Journal 7 NA (2013): 59-71. https://research.unl.pt/en/publications/multidrug-efflux-pumps-in-staphylococcus-aureus-an-update(04af8331-c342-4bdb-8dde-3966a927d2bc).html.
    10.2174/1874285801307010059
  167. Sofia Costa; Celeste Falcão; Miguel Viveiros; Diana Machado; Marta Martins; José Melo-Cristino; Leonard Amaral; Isabel Couto. "Correction: Exploring the contribution of efflux on the resistance to fluoroquinolones in clinical isolates of Staphylococcus aureus". BMC Microbiology 13 1 (2013): 127-127. http://dx.doi.org/10.1186/1471-2180-13-127.
    10.1186/1471-2180-13-127
  168. Veigas, Bruno; Pedrosa, Pedro; Couto, Isabel; Viveiros, Miguel; Baptista, Pedro V.. "Isothermal DNA amplification coupled to Au-nanoprobes for detection of mutations associated to Rifampicin resistance in Mycobacterium tuberculosis". (2013): http://hdl.handle.net/10362/100686.
    https://doi.org/10.1186/1477-3155-11-38
  169. Perdigão, joão; Macedo, Rita; Machado, Diana; Silva, Carla; Jordão, Luísa; Couto, Isabel; Viveiros, Miguel; et al. "GidB mutation as a phylogenetic marker for Q1 cluster Mycobacterium tuberculosis isolates and intermediate-level streptomycin resistance determinant in Lisbon, Portugal". Clinical Microbiology and Infection 20 5 (2013): https://www.authenticus.pt/P-010-V6K.
    10.1111/1469-0691.12392
  170. Miguel Viveiros; Rodrigo Martins; Pedro Barquinha; Elvira Fortunato; P. V. Baptista. "Gold on paper-paper platform for Au-nanoprobe TB detection". Lab On A Chip 12 22 (2012): 4802-8. https://research.unl.pt/en/publications/gold-on-paperpaper-platform-for-aunanoprobe-tb-detection(0a0a1763-9d4b-404b-8ee7-7dcb84d82ce6).html.
    10.1039/c2lc40739f
  171. Liliana Rodrigues; Diana Machado; Isabel Couto; Leonard Amaral; Miguel Viveiros. "Contribution of efflux activity to isoniazid resistance in the Mycobacterium tuberculosis complex". Infection Genetics And Evolution 12 4 (2012): 695-700. https://research.unl.pt/en/publications/contribution-of-efflux-activity-to-isoniazid-resistance-in-the-mycobacterium-tuberculosis-complex(f2c4ea6f-0c4b-4e78-a4c7-bcf78a21bdfc).html.
    10.1016/j.meegid.2011.08.009
  172. Diana Machado; Isabel Couto; Liliana Rodrigues; P. V. Baptista; Bruno Veigas; Miguel Viveiros; Leonard Amaral. "Contribution of Efflux to the Emergence of Isoniazid and Multidrug Resistance in Mycobacterium tuberculosis.". Plos One 7 4 (2012): e34538-e34538. https://research.unl.pt/en/publications/contribution-of-efflux-to-the-emergence-of-isoniazid-and-multidrug-resistance-in-mycobacterium-tuberculosis(4f80727c-69c9-4c79-9e84-3a2fff2617e8).html.
    10.1371/journal.pone.0034538
  173. Dymek A; Armada A; Handzlik J; Viveiros M; Spengler G; Molnar J; Kiec-Kononowicz K; Amaral L. "The activity of 16 new hydantoin compounds on the intrinsic and overexpressed efflux pump system of Staphylococcus aureus.". In Vivo (2012): http://europepmc.org/abstract/med/22351662.
  174. Leonard Amaral; Ana Martins; Miguel Viveiros; Isabel Couto; Sofia Santos Costa; Marta Martins. "Genetic response of Salmonella enterica serotype Enteritidis to thioridazine rendering the organism resistant to the agent.". International Journal Of Antimicrobial Agents 39 1 (2012): 16-21. https://research.unl.pt/en/publications/genetic-response-of-salmonella-enterica-serotype-enteritidis-to-thioridazine-rendering-the-organism-resistant-to-the-agent(9480871f-8741-4209-9d04-5f6377b5db67).html.
    10.1016/j.ijantimicag.2011.08.013
  175. Miguel Viveiros; Leonard Amaral; Isabel Couto. "Inhibitors of mycobacterial efflux pumps as potential boosters for anti-tubercular drugs.". Expert Review Of Anti-Infective Therapy 10 9 (2012): 983-998. https://research.unl.pt/en/publications/inhibitors-of-mycobacterial-efflux-pumps-as-potential-boosters-for-antitubercular-drugs(268b7625-7450-4be5-abc3-32d4150d9b67).html.
    10.1586/eri.12.89
  176. Miguel Viveiros; Isabel Couto. "Using Au-nanoprobes por point-of-need diagnostics of TB.". Microbiologia online 1 (2012): online-online. https://research.unl.pt/en/publications/using-aunanoprobes-por-pointofneed-diagnostics-of-tb(f61729c0-46ff-4d34-aaae-12eda27028f1).html.
  177. Leonard Amaral; Miguel Viveiros. "Why thioridazine in combination with antibiotics cures extensively drug-resistant Mycobacterium tuberculosis infections". International Journal Of Antimicrobial Agents 39 5 (2012): 376-380. https://research.unl.pt/en/publications/why-thioridazine-in-combination-with-antibiotics-cures-extensively-drugresistant-mycobacterium-tuberculosis-infections(16d0c0ce-904f-4288-84be-2893850e785e).html.
    10.1016/j.ijantimicag.2012.01.012
  178. Miguel Viveiros. "Edição Comemorativa dos Anais: O ensino das ciências médicas e biomédicas no Instituto de Higiene e Medicina Tropical – a contextualização histórico-pedagógica.". Anais Do Instituto De Higiene E Medicina Tropical 11 (2012): https://research.unl.pt/en/publications/edicao-comemorativa-dos-anais-o-ensino-das-ciencias-medicas-e-biomedicas-no-instituto-de-higiene-e-medicina-tropical--a-contextualizacao-historicopedagogica(62bb4661-2cc6-4c1d-aa6c-744cd463c70b).html.
  179. Faculdade de Ciências. "Synthesis and thermochemical study of quinoxaline-N-oxides: enthalpies of dissociation of the N-O bond". (2012): 0894-3230.
    10.1002/poc.1932
  180. Machado, D; Couto, Isabel Maria dos Santos Leitão; Perdigão, João; Rodrigues, Liliana; Portugal, Isabel; Baptista, Pedro; Veigas, Bruno; Amaral, Leonard; Bettencourt, Miguel Viveiros. "Contribution of Efflux to the Emergence of Isoniazid and Multidrug Resistance in Mycobacterium tuberculosis.". (2012): http://hdl.handle.net/10362/117077.
    https://doi.org/10.1371/journal.pone.0034538
  181. Gabriella Spengler; Joseph Molnar; Miguel Viveiros; Leonard Amaral. "Thioridazine induces apoptosis of multidrug-resistant mouse lymphoma cells transfected with the human ABCB1 and inhibits the expression of P-glycoprotein". Anticancer Research 31 12 (2011): 4201-5. https://research.unl.pt/en/publications/thioridazine-induces-apoptosis-of-multidrugresistant-mouse-lymphoma-cells-transfected-with-the-human-abcb1-and-inhibits-the-expression-of-pglycoprotein(5fba65fc-e81c-4324-a696-0d117d45cc8b).html.
  182. Sofia Santos Costa; Celeste Falcão; Miguel Viveiros; Diana Machado; Marta Martins; José Melo-Cristino; Leonard Amaral; Isabel Couto. "Exploring the contribution of efflux on the resistance to fluoroquinolones in clinical isolates of Staphylococcus aureus". Bmc Microbiology 11 (2011): 241-241. https://research.unl.pt/en/publications/exploring-the-contribution-of-efflux-on-the-resistance-to-fluoroquinolones-in-clinical-isolates-of-staphylococcus-aureus(2d5a98ed-d260-4d76-bb02-5379b696ad01).html.
    10.1186/1471-2180-11-241
  183. Spengler G; Handzlik J; Ocsovszki I; Viveiros M; Kiec-Kononowicz K; Molnar J; Amaral L. "Modulation of multidrug efflux pump activity by new hydantoin derivatives on colon adenocarcinoma cells without inducing apoptosis.". Anticancer research (2011): http://europepmc.org/abstract/med/21965738.
  184. Lisa Machado; Gabriella Spengler; Miguel Evaristo; Jadwiga Handzlik; Joseph Molnár; Miguel Viveiros; Katarzyna Kiec-Kononowicz; Leonard Amaral. "Biological activity of twenty-three hydantoin derivatives on intrinsic efflux pump system of Salmonella enterica serovar enteritidis NCTC 13349". In Vivo 25 5 (2011): 769-772. https://research.unl.pt/en/publications/biological-activity-of-twentythree-hydantoin-derivatives-on-intrinsic-efflux-pump-system-of-salmonella-enterica-serovar-enteritidis-nctc-13349(c1e82ed5-027d-4c99-91d8-52230b623f5a).html.
  185. Daniella Takács; Pedro Cerca; Ana Martins; Zsuzsanna Riedl; György Hajós; Joseph Molnár; Miguel Viveiros; Isabel Couto; Leonard Amaral. "Evaluation of forty new phenothiazine derivatives for activity against intrinsic efflux pump systems of reference Escherichia coli, Salmonella enteritidis, Enterococcus faecalis and Staphylococcus aureus strains". In Vivo 25 5 (2011): 719-724. https://research.unl.pt/en/publications/evaluation-of-forty-new-phenothiazine-derivatives-for-activity-against-intrinsic-efflux-pump-systems-of-reference-escherichia-coli-salmonella-enteritidis-enterococcus-faecalis-and-staphylococcus-aure(aa96152c-ac41-4.
  186. Martins M; Viveiros M; Couto I; Costa SS; Pacheco T; Fanning S; Pagès JM; Amaral L. "Identification of efflux pump-mediated multidrug-resistant bacteria by the ethidium bromide-agar cartwheel method.". In Vivo (2011): http://europepmc.org/abstract/med/21471531.
  187. Ana Martins; L, Machado; S. Costa; P, Cerca; G. Spengler; Miguel Viveiros; Leonard Amaral. "Role of calcium in the efflux system of Escherichia coli.". International Journal Of Antimicrobial Agents 37 5 (2011): 410-414. https://research.unl.pt/en/publications/role-of-calcium-in-the-efflux-system-of-escherichia-coli(865b70b0-2c27-45e6-95a5-d4660562156d).html.
    10.1016/j.ijantimicag.2011.01.010
  188. P, Cerca; Ana Martins; Isabel Couto; Miguel Viveiros; Leonard Amaral. "Competition between substrates of the efflux pump system of Salmonella enteritidis.". In vivo (Athens, Greece) 25 4 (2011): 597-602. https://research.unl.pt/en/publications/competition-between-substrates-of-the-efflux-pump-system-of-salmonella-enteritidis(bbb3a9aa-0235-416f-8a8a-3cb30de45e45).html.
  189. Ana Martins; A. Vasas; Miguel Viveiros; J Molnár; J. Hohmann; Leonard Amaral. "Antibacterial properties of compounds isolated from Carpobrotus edulis.". International Journal Of Antimicrobial Agents 37 5 (2011): 438-444. https://research.unl.pt/en/publications/antibacterial-properties-of-compounds-isolated-from-carpobrotus-edulis(ebb51e70-14e4-4fff-be48-5c6b97fb6c2c).html.
    10.1016/j.ijantimicag.2011.01.016
  190. L, Rodrigues; J, Ramos; Isabel Couto; Leonard Amaral; Miguel Viveiros; Rodrigues , Liliana; Ramos, Jorge; et al. "Ethidium bromide transport across Mycobacterium smegmatis cell-wall: correlation with antibiotic resistance.". Bmc Microbiology 11 NA (2011): 35-35. https://research.unl.pt/en/publications/ethidium-bromide-transport-across-mycobacterium-smegmatis-cellwall-correlation-with-antibiotic-resistance(a95c3627-3ddf-441d-b10a-df02f43c68d7).html.
    10.1186/1471-2180-11-35
  191. Leonard Amaral; M Martins; Miguel Viveiros. "Thioridazine: alternative and potentially effective therapy of the XDR-TB patient.". Letters In Drug Design & Discovery 8 2 (2011): 130-132. https://research.unl.pt/en/publications/thioridazine-alternative-and-potentially-effective-therapy-of-the-xdrtb-patient(5e02ba83-14ea-41aa-8114-cf005ef247b0).html.
    10.2174/157018011794183860
  192. Rodrigues, L.; Aínsa, J.A.; Amaral, L.; Viveiros, M.. "Inhibition of drug efflux in mycobacteria with phenothiazines and other putative efflux inhibitors". Recent Patents on Anti-Infective Drug Discovery 6 2 (2011): 118-127. http://www.scopus.com/inward/record.url?eid=2-s2.0-79960065506&partnerID=MN8TOARS.
    10.2174/157489111796064579
  193. Amaral, L.; Cerca, P.; Spengler, G.; MacHado, L.; Martins, A.; Couto, I.; Viveiros, M.; Fanning, S.; Pags, J.-M.. "Ethidium bromide efflux by Salmonella: Modulation by metabolic energy, pH, ions and phenothiazines". International Journal of Antimicrobial Agents 38 2 (2011): 140-145. http://www.scopus.com/inward/record.url?eid=2-s2.0-79959759805&partnerID=MN8TOARS.
    10.1016/j.ijantimicag.2011.03.014
  194. Pascu, M.-L.; Nastasa, V.; Smarandache, A.; Militaru, A.; Martins, A.; Viveiros, M.; Boni, M.; et al. "Direct modification of bioactive phenothiazines by exposure to laser radiation". Recent Patents on Anti-Infective Drug Discovery 6 2 (2011): 147-157. http://www.scopus.com/inward/record.url?eid=2-s2.0-79959994231&partnerID=MN8TOARS.
    10.2174/157489111796064515
  195. Amara, L.; Viveiros, M.; Molnar, J.; Kristiansen, J.E.. "Effective therapy with the neuroleptic thioridazine as an adjunct to second line of defence drugs, and the potential that thioridazine offers for new patents that cover a variety of ''New Uses''". Recent Patents on Anti-Infective Drug Discovery 6 2 (2011): 84-87. http://www.scopus.com/inward/record.url?eid=2-s2.0-79959996814&partnerID=MN8TOARS.
    10.2174/157489111796064542
  196. Ramalhete, C.; Spengler, G.; Martins, A.; Martins, M.; Viveiros, M.; Mulhovo, S.; Ferreira, M.-J.U.; Amaral, L.. "Inhibition of efflux pumps in meticillin-resistant Staphylococcus aureus and Enterococcus faecalis resistant strains by triterpenoids from Momordica balsamina". International Journal of Antimicrobial Agents 37 1 (2011): 70-74. http://www.scopus.com/inward/record.url?eid=2-s2.0-78650262885&partnerID=MN8TOARS.
    10.1016/j.ijantimicag.2010.09.011
  197. Machado, LisaSantos. "The Inhibitory Activity of Synthetic Compounds and Ions Against Transporters of Multi-drug Resistant Bacteria". Universidade NOVA de Lisboa (Portugal) (2011): https://publons.com/wos-op/publon/64719086/.
  198. Kristiansen JE; Thomsen VF; Martins A; Viveiros M; Amaral L. "Non-antibiotics reverse resistance of bacteria to antibiotics.". In Vivo (2010): http://europepmc.org/abstract/med/20952744.
  199. A. Martins; A. Vasas; Z. S. Schelz; Miguel Viveiros; Joseph Molnar; J. Hohmann; L. Amaral. "Constituents of Carpobrotus edulis Inhibit P-Glycoprotein of MDR1-transfected Mouse Lymphoma Cells". Anticancer Research 30 3 (2010): 829-835. https://research.unl.pt/en/publications/constituents-of-carpobrotus-edulis-inhibit-pglycoprotein-of-mdr1transfected-mouse-lymphoma-cells(7a37d487-12e5-497a-a2c2-3dbae69ac091).html.
  200. Leonard Amaral; Miguel Viveiros. "Biological Activity of Hydantoin Derivatives on P-Glycoprotein (ABCB1) of Mouse Lymphoma Cells.". Anticancer Research 30 12 (2010): 4867-4871. https://research.unl.pt/en/publications/biological-activity-of-hydantoin-derivatives-on-pglycoprotein-abcb1-of-mouse-lymphoma-cells(f1af5fe1-fd80-4a7a-9b80-9637a5c7d7f6).html.
  201. Leonard Amaral; A, Martins; J, Molnár; JE, Kristiansen; M, Martins; Miguel Viveiros; L, Rodrigues; et al. "Thioridazine cures extensively drug-resistant tuberculosis (XDR-TB) and the need for global trials is now!". International Journal Of Antimicrobial Agents 35 6 (2010): 524-6. https://research.unl.pt/en/publications/thioridazine-cures-extensively-drugresistant-tuberculosis-xdrtb-and-the-need-for-global-trials-is-now(74bcade5-7cd5-4922-b3fc-97944065d5c6).html.
    10.1016/j.ijantimicag.2009.12.019
  202. J, Chevalier; A, Mahamoud; M, Baitiche; E, Adam; Miguel Viveiros; A, Smarandache; A, Militaru; et al. "Quinazoline derivatives are efficient chemosensitizers of antibiotic activity in Enterobacter aerogenes, Klebsiella pneumoniae and Pseudomonas aeruginosa resistant strains.". International Journal Of Antimicrobial Agents 36 2 (2010): 164-168. https://research.unl.pt/en/publications/quinazoline-derivatives-are-efficient-chemosensitizers-of-antibiotic-activity-in-enterobacter-aerogenes-klebsiella-pneumoniae-and-pseudomonas-aeruginosa-resistant-strains(fc26a076-2106-4cbf-81f1-83515193e57b).html.
    10.1016/j.ijantimicag.2010.03.027
  203. Leonard Amaral; Isabel Couto; Miguel Viveiros. "Phenothiazines, bacterial efflux pumps and targeting the macrophage for enhanced killing of intracellular XDRTB.". In Vivo 24 4 (2010): 409-24. https://research.unl.pt/en/publications/phenothiazines-bacterial-efflux-pumps-and-targeting-the-macrophage-for-enhanced-killing-of-intracellular-xdrtb(4dceb97c-78b6-4568-8a08-17eee159d483).html.
  204. Miguel Viveiros; M Martins; Isabel Couto; L Rodrigues; Diana Machado; I, Portugal; Leonard Amaral. "Molecular tools for rapid identification and novel effective therapy against MDRTB/XDRTB infections.". Expert Review Of Anti-Infective Therapy 8 4 (2010): 465-80. https://research.unl.pt/en/publications/molecular-tools-for-rapid-identification-and-novel-effective-therapy-against-mdrtbxdrtb-infections(1a6357bd-6bd7-42d9-8971-fef672c368aa).html.
    10.1586/eri.10.20
  205. Isabel Couto; Diana Machado; Miguel Viveiros; L, Rodrigues; Leonard Amaral. "Identification of nontuberculous mycobacteria in clinical samples using molecular methods: a 3-year study.". Clinical Microbiology and Infection 16 8 (2010): 1161-4. https://research.unl.pt/en/publications/identification-of-nontuberculous-mycobacteria-in-clinical-samples-using-molecular-methods-a-3year-study(9f3654d8-6af6-40c2-a10d-5885a74e643f).html.
    10.1111/j.1469-0691.2009.03076.x
  206. Leonard Amaral; Isabel Couto; Miguel Viveiros. "Physiological characterisation of the efflux pump system of antibiotic-susceptible and multidrug-resistant Enterobacter aerogenes.". International Journal Of Antimicrobial Agents 36 4 (2010): 313-318. https://research.unl.pt/en/publications/physiological-characterisation-of-the-efflux-pump-system-of-antibioticsusceptible-and-multidrugresistant-enterobacter-aerogenes(476a7457-e521-4833-a63d-da9839b03b42).html.
    10.1016/j.ijantimicag.2010.06.036
  207. Isabel Couto; Miguel Viveiros; P. V. Baptista. "Au-nanoprobes for detection of SNPs associated with antibiotic resistance in Mycobacterium tuberculosis.". Nanotechnology 21 41 (2010): 415101-415101. https://research.unl.pt/en/publications/aunanoprobes-for-detection-of-snps-associated-with-antibiotic-resistance-in-mycobacterium-tuberculosis(410472c4-7c42-4661-8721-34d5c9f1a879).html.
    10.1088/0957-4484/21/41/415101
  208. Sofia Santos Costa; E, Ntokou; A, Martins; Miguel Viveiros; S, Pouranas; Leonard Amaral; Isabel Couto. "Identification of the plasmid-encoded qacA efflux pump gene in meticillin-resistant Staphylococcus aureus (MRSA) strain HPV107, a representative of the MRSA Iberian clone.". International Journal Of Antimicrobial Agents 36 6 (2010): 557-61. https://research.unl.pt/en/publications/identification-of-the-plasmidencoded-qaca-efflux-pump-gene-in-meticillinresistant-staphylococcus-aureus-mrsa-strain-hpv107-a-representative-of-the-mrsa-iberian-clone(3b723a33-fb4e-40ee-b1b8-dab03bbc7b78).html.
    10.1016/j.ijantimicag.2010.08.006
  209. Miguel Viveiros; Liliana Rodrigues; Marta Martins; Isabel Couto; Gabriella Spengler; Ana Martins; Leonard Amaral. "Evaluation of efflux activity of bacteria by a semi-automated fluorometric system". Methods In Molecular Biology (Clifton, N.J.) 642 (2010): 159-72. https://research.unl.pt/en/publications/evaluation-of-efflux-activity-of-bacteria-by-a-semiautomated-fluorometric-system(3e302ca5-1108-4948-b7c4-16c82c7f9ad4).html.
    10.1007/978-1-60327-279-7_12
  210. Marta Martins; Miguel Viveiros; Diane Ordway; Jette E. Kristiansen; Joseph Molnar; Leonard Amaral. "Reserpine, ouabain and the calcium channel blocker verapamil, cause intracellular killing of Staphylococcus aureus". Research Journal of Microbiology 5 6 (2010): 490-496. https://research.unl.pt/en/publications/reserpine-ouabain-and-the-calcium-channel-blocker-verapamil-cause-intracellular-killing-of-staphylococcus-aureus(29ea7e83-8af4-4d2a-8b37-0876c0f8aac4).html.
    10.3923/jm.2006.203.209
  211. Martins, M.; Couto, I.; Viveiros, M.; Amaral, L.. "Identification of efflux-mediated multi-drug resistance in bacterial clinical isolates by two simple methods.". Methods in molecular biology (Clifton, N.J.) 642 (2010): 143-157. http://www.scopus.com/inward/record.url?eid=2-s2.0-77954672260&partnerID=MN8TOARS.
    10.1007/978-1-60327-279-7_11
  212. Costa, Susana Cristina Nunes Santos Nunes Santos; COSTA, Susana; COSTA, Susana Cristina Nunes Santos. "Caracterização Preliminar da Bioenergética do Efluxo Pelo Sistema Acrab-tolc em Escherichia Coli". Universidade NOVA de Lisboa (Portugal) (2010): https://publons.com/wos-op/publon/64719085/.
  213. Martins A; Spengler G; Rodrigues L; Viveiros M; Ramos J; Martins M; Couto I; et al. "pH Modulation of efflux pump activity of multi-drug resistant Escherichia coli: protection during its passage and eventual colonization of the colon.". PloS one (2009): http://europepmc.org/abstract/med/19684858.
    10.1371/journal.pone.0006656
  214. Spengler G; Viveiros M; Martins M; Rodrigues L; Martins A; Molnar J; Couto I; Amaral L. "Demonstration of the activity of P-glycoprotein by a semi-automated fluorometric method.". Anticancer research (2009): http://europepmc.org/abstract/med/19528478.
  215. Gabriella Spengler; Ana Martins; Zsuzsanna Schelz; Liliana Rodrigues; Lone Aagaard; Marta Martins; Sofia Santos Costa; et al. "Characterization of intrinsic efflux activity of Enterococcus faecalis ATCC29212 by a semi-automated ethidium bromide method". In Vivo 23 1 (2009): 81-7. https://research.unl.pt/en/publications/characterization-of-intrinsic-efflux-activity-of-enterococcus-faecalis-atcc29212-by-a-semiautomated-ethidium-bromide-method(c61939f9-dbe3-4718-8929-fb0f970be727).html.
  216. Leonard Amaral; Miguel Viveiros; Isabel Couto. "An AcrAB-mediated multidrug-resistant phenotype is maintained following restoration of wild-type activities by efflux pump genes and their regulators". International Journal Of Antimicrobial Agents 34 6 (2009): 602-604. https://research.unl.pt/en/publications/an-acrabmediated-multidrugresistant-phenotype-is-maintained-following-restoration-of-wildtype-activities-by-efflux-pump-genes-and-their-regulators(f5824dcd-c5b1-46eb-af6c-e2eb636ad524).html.
    10.1016/j.ijantimicag.2009.06.029
  217. Leonard Amaral; Miguel Viveiros; Isabel Couto. "Fluorometric determination of ethidium bromide efflux kinetics in Escherichia coli.". Journal Of Biological Engineering 3 NA (2009): 18-18. https://research.unl.pt/en/publications/fluorometric-determination-of-ethidium-bromide-efflux-kinetics-in-escherichia-coli(9a66e485-80b4-4a1b-aec4-6bfa9060b9ba).html.
    10.1186/1754-1611-3-18
  218. Leonard Amaral; Miguel Viveiros; Isabel Couto. "The role of efflux pumps in macrolide resistance in Mycobacterium avium complex". International Journal Of Antimicrobial Agents 34 6 (2009): 529-533. https://research.unl.pt/en/publications/the-role-of-efflux-pumps-in-macrolide-resistance-in-mycobacterium-avium-complex(0924160f-b4d4-41ed-868d-be68bb03c3e6).html.
    10.1016/j.ijantimicag.2009.07.010
  219. Miguel Viveiros; Leonard Amaral; Isabel Couto. "SILA 421, an inhibitor of efflux pumps of cancer cells, enhances the killing of intracellular extensively drug-resistant tuberculosis (XDR-TB)". International Journal Of Antimicrobial Agents 33 5 (2009): 479-482. https://research.unl.pt/en/publications/sila-421-an-inhibitor-of-efflux-pumps-of-cancer-cells-enhances-the-killing-of-intracellular-extensively-drugresistant-tuberculosis-xdrtb(bbfd06a7-9363-48df-b32f-59f8a2490489).html.
    10.1016/j.ijantimicag.2008.10.028
  220. Miguel Viveiros; Leonard Amaral; Isabel Couto. "Targeting human macrophages for enhanced killing of intracellular XDR-TB and MDR-TB.". International Journal Of Tuberculosis And Lung Disease 13 5 (2009): 569-73. https://research.unl.pt/en/publications/targeting-human-macrophages-for-enhanced-killing-of-intracellular-xdrtb-and-mdrtb(0abde695-e879-4be9-8b3f-ce2ddcd65080).html.
  221. Spengler, G.; Ramalhete, C.; Martins, M.; Martins, A.; Serly, J.; Viveiros, M.; Molnár, J.; et al. "Evaluation of cucurbitane-type triterpenoids from Momordica balsamina on P-glycoprotein (ABCB1) by flow cytometry and real-time fluorometry". Anticancer Research 29 10 (2009): 3989-3993. http://www.scopus.com/inward/record.url?eid=2-s2.0-71949083688&partnerID=MN8TOARS.
  222. Marta Martins; Miguel Viveiros; Leonard Amaral. "The TB laboratory of the future". Future Microbiology 3 2 (2008): 135-144. https://research.unl.pt/en/publications/the-tb-laboratory-of-the-future(3a9c3aef-56ef-4473-b0dd-f53a8016e980).html.
    10.2217/17460913.3.2.135
  223. Marta Martins; Miguel Viveiros; Leonard Amaral. "Inhibitors of Ca2+ and K+ transport enhance intracellular killing of M-tuberculosis by non-killing macrophages". In Vivo 22 1 (2008): 69-75. https://research.unl.pt/en/publications/inhibitors-of-ca2-and-k-transport-enhance-intracellular-killing-of-mtuberculosis-by-nonkilling-macrophages(1acf472d-2e82-4f36-8187-7fab48b71422).html.
  224. Viveiros, M; Martins, A; Paixao, L; Rodrigues, L; Martins, M; Couto, I; Faehnrich, E; Kern, WV; Amaral, L. "Demonstration of intrinsic efflux activity of Escherichia coli K-12 AG100 by an automated ethidium bromide method". INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2008):
    10.1016/j.ijantimicag.2007.12.015
  225. Martins, M.; Viveiros, M.; Amaral, L.. "Enhanced killing of intracellular pathogenic bacteria by phenothiazines and the role of K+ efflux pumps of the bacterium and the killing macrophage". Anti-Infective Agents in Medicinal Chemistry 7 1 (2008): 63-72. http://www.scopus.com/inward/record.url?eid=2-s2.0-41149156855&partnerID=MN8TOARS.
    10.2174/187152108783329807
  226. Martins, M.; Dastidar, S.G.; Fanning, S.; Kristiansen, J.E.; Molnar, J.; Pagès, J.-M.; Schelz, Z.; et al. "Potential role of non-antibiotics (helper compounds) in the treatment of multidrug-resistant Gram-negative infections: mechanisms for their direct and indirect activities". International Journal of Antimicrobial Agents 31 3 (2008): 198-208. http://www.scopus.com/inward/record.url?eid=2-s2.0-39149121434&partnerID=MN8TOARS.
    10.1016/j.ijantimicag.2007.10.025
  227. Rodrigues, L.; Wagner, D.; Viveiros, M.; Sampaio, D.; Couto, I.; Vavra, M.; Kern, W.V.; Amaral, L.. "Thioridazine and chlorpromazine inhibition of ethidium bromide efflux in Mycobacterium avium and Mycobacterium smegmatis". Journal of Antimicrobial Chemotherapy 61 5 (2008): 1076-1082. http://www.scopus.com/inward/record.url?eid=2-s2.0-42149168442&partnerID=MN8TOARS.
    10.1093/jac/dkn070
  228. Amaral, L.; Martins, M.; Viveiros, M.; Molnar, J.; Kristiansen, J.E.. "Promising therapy of XDR-TB/MDR-TB with thioridazine an inhibitor of bacterial efflux pumps". Current Drug Targets 9 9 (2008): 816-819. http://www.scopus.com/inward/record.url?eid=2-s2.0-52449123326&partnerID=MN8TOARS.
    10.2174/138945008785747798
  229. Couto, I.; Costa, S.S.; Viveiros, M.; Martins, M.; Amaral, L.; Couto, Isabel; Costa, Sofia Santos; et al. "Efflux-mediated response of Staphylococcus aureus exposed to ethidium bromide". Journal of Antimicrobial Chemotherapy 62 3 (2008): 504-513. http://www.scopus.com/inward/record.url?eid=2-s2.0-49649085104&partnerID=MN8TOARS.
    10.1093/jac/dkn217
  230. Marta Martins; Miguel Viveiros; Jette E. Kristiansen; Joseph Molnar; Leonard Amaral. "The curative activity of thioridazine on mice infected with Mycobacterium tuberculosis". In Vivo 21 5 (2007): 771-776. https://research.unl.pt/en/publications/the-curative-activity-of-thioridazine-on-mice-infected-with-mycobacterium-tuberculosis(ffeaa1b8-aaa8-4821-9cb4-a2eae377ae60).html.
  231. Noélia Duarte; Maria José U Ferreira; Marta Martins; Miguel Viveiros; Leonard Amaral. "Antibacterial activity of ergosterol peroxide against Mycobacterium tuberculosis". Phytotherapy Research 21 7 (2007): 601-604. https://research.unl.pt/en/publications/antibacterial-activity-of-ergosterol-peroxide-against-mycobacterium-tuberculosis(fc094880-9fe3-43d2-a9a0-d8558361b217).html.
    10.1002/ptr.2119
  232. Zsuzsanna Schelz; Marta Martins; Ana Martins; Miguel Viveiros; Joseph Molnar; Leonard Amaral. "Elimination of plasmids by SILA compounds that inhibit efflux pumps of bacteria and cancer cells". In Vivo 21 4 (2007): 635-640. https://research.unl.pt/en/publications/elimination-of-plasmids-by-sila-compounds-that-inhibit-efflux-pumps-of-bacteria-and-cancer-cells(dd5b8258-e90a-423e-8ca3-e15dffd8e0ca).html.
  233. Amaral, L.; Engi, H.; Viveiros, M.; Molnar, J.. "Comparison of multidrug resistant efflux pumps of cancer and bacterial cells with respect to the same inhibitory agents". In Vivo 21 2 (2007): 237-244. http://www.scopus.com/inward/record.url?eid=2-s2.0-34047222991&partnerID=MN8TOARS.
  234. Amaral, L.; Martins, M.; Viveiros, M.. "Enhanced killing of intracellular multidrug-resistant Mycobacterium tuberculosis by compounds that affect the activity of efflux pumps". Journal of Antimicrobial Chemotherapy 59 6 (2007): 1237-1246. http://www.scopus.com/inward/record.url?eid=2-s2.0-34447542162&partnerID=MN8TOARS.
    10.1093/jac/dkl500
  235. Martins, M.; Schelz, Z.; Martins, A.; Molnar, J.; Hajös, G.; Riedl, Z.; Viveiros, M.; et al. "In vitro and ex vivo activity of thioridazine derivatives against Mycobacterium tuberculosis". International Journal of Antimicrobial Agents 29 3 (2007): 338-340. http://www.scopus.com/inward/record.url?eid=2-s2.0-33846969173&partnerID=MN8TOARS.
    10.1016/j.ijantimicag.2006.10.013
  236. Amaral, L.; Martins, M.; Viveiros, M.. "Phenothiazines as anti-multi-drug resistant tubercular agents". Infectious Disorders - Drug Targets 7 3 (2007): 257-265. http://www.scopus.com/inward/record.url?eid=2-s2.0-35649009444&partnerID=MN8TOARS.
    10.2174/187152607782110022
  237. Martins, A.; Couto, I.; Aagaard, L.; Martins, M.; Viveiros, M.; Kristiansen, J.E.; Amaral, L.. "Prolonged exposure of methicillin-resistant Staphylococcus aureus (MRSA) COL strain to increasing concentrations of oxacillin results in a multidrug-resistant phenotype". International Journal of Antimicrobial Agents 29 3 (2007): 302-305. http://www.scopus.com/inward/record.url?eid=2-s2.0-33846939351&partnerID=MN8TOARS.
    10.1016/j.ijantimicag.2006.10.012
  238. Duarte, Noelia; Ferreira, Maria-Jose U.; Martins, Marta; Viveiros, Miguel; Amaral, Leonard. "Antibacterial activity of ergosterol peroxide against Mycobacterium tuberculosis". (2007): http://hdl.handle.net/10451/21440.
    http://dx.doi.org/10.1002/ptr.2119
  239. Viveiros, Miguel; Dupont, Myrielle; Rodrigues, Liliana; Couto, Isabel; Davin-Regli, Anne; Martins, Marta; Pagès, Jean Marie; et al. "Antibiotic stress, genetic response and altered permeability of E. coli". PLOS ONE (2007): http://hdl.handle.net/10362/117209.
    https://doi.org/10.1371/journal.pone.0000365
  240. Martins M; Santos B; Martins A; Viveiros M; Couto I; Cruz A; Pagès JM; et al. "An instrument-free method for the demonstration of efflux pump activity of bacteria.". In vivo (Athens, Greece) (2006): http://europepmc.org/abstract/med/17091774.
  241. Kristina Wolfart; Gabriella Spengler; Masami Kawase; Noboru Motohashi; Joseph Molnr; Miguel Viveiros; Leonard Amaral. "Synergistic interaction between proton pump inhibitors and resistance modifiers". In Vivo 20 3 (2006): 367-372. https://research.unl.pt/en/publications/synergistic-interaction-between-proton-pump-inhibitors-and-resistance-modifiers(740ea607-96a5-4fec-a406-7b990ba58100).html.
  242. Malthe M. Kristiansen; Clara Leandro; Diane Ordway; Marta Martins; Miguel Viveiros; Teresa Pacheco; Joseph Molnar; Jette E. Kristiansen; Leonard Amaral. "Thioridazine reduces resistance of methicillin-resistant Staphylococcus aureus by inhibiting a reserpine-sensitive efflux pump". In Vivo 20 3 (2006): 361-366. https://research.unl.pt/en/publications/thioridazine-reduces-resistance-of-methicillinresistant-staphylococcus-aureus-by-inhibiting-a-reserpinesensitive-efflux-pump(890b5163-3167-417a-a31f-a5a85c93cbe7).html.
  243. Amaral, L.; Viveiros, M.; Kristiansen, J.E.. ""Non-antibiotics": Alternative therapy for the management of MDRTB and MRSA in economically disadvantaged countries". Current Drug Targets 7 7 (2006): 887-891. http://www.scopus.com/inward/record.url?eid=2-s2.0-33745738994&partnerID=MN8TOARS.
    10.2174/138945006777709539
  244. Miguel Viveiros; Ana R. Jesus; Mafalda Brito; Clara Leandro; Marta Martins; Diane Ordway; Ana Maria Molnar; Joseph Molnar; Leonard Amaral. "Inducement and reversal of tetracycline resistance in Escherichia coli K-12 and expression of proton gradient-dependent multidrug efflux pump genes". Antimicrobial Agents and Chemotherapy -Journal- 49 8 (2005): 3578-3582. https://research.unl.pt/en/publications/inducement-and-reversal-of-tetracycline-resistance-in-escherichia-coli-k12-and-expression-of-proton-gradientdependent-multidrug-efflux-pump-genes(d09c3293-07b6-4d19-8115-6b4c2d8589a5).html.
    10.1128/aac.49.8.3578-3582.2005
  245. Miguel Viveiros; Marta Martins; Isabel Couto; Jette E. Kristiansen; Joseph Molnar; Leonard Amaral. "The in vitro activity of phenothiazines against Mycobacterium avium". In Vivo 19 4 (2005): 733-736. https://research.unl.pt/en/publications/the-in-vitro-activity-of-phenothiazines-against-mycobacterium-avium(fbdec778-4c28-4150-8719-f1d9b476b329).html.
  246. Diane J. Ordway; Miguel Viveiros; Fernando A. Ventura; Ian M. Orme; Hazel M. Dockrell; Leonard Amaral. "Exogenous Re-infection by Multiple Exposures to Mycobacterium tuberculosis Contributes to Subsequent Development of Active Tuberculosis". American Journal of Immunology 1 1 (2005): 42-47. http://dx.doi.org/10.3844/ajisp.2005.42.47.
    10.3844/ajisp.2005.42.47
  247. Marta Martins; Diane Ordway; Malthe M. Kristiansen; Miguel Viveiros; Clara Leandro; Joseph Molnar; Leonard Amaral. "Inhibition of the Carpobrotus edulis methanol extract on the growth of phagocytosed multidrug-resistant Mycobacterium tuberculosis and methicillin-resistant Staphylococcus aureus". Fitoterapia 76 1 (2005): 96-99. https://research.unl.pt/en/publications/inhibition-of-the-carpobrotus-edulis-methanol-extract-on-the-growth-of-phagocytosed-multidrugresistant-mycobacterium-tuberculosis-and-methicillinresistant-staphylococcus-aureus(3b85af21-61d8-4375-8c9c-83e5cf5bdbca)..
    10.1016/j.fitote.2004.09.020
  248. Viveiros, M; Leandro, C; Rodrigues, L; Almeida, J; Bettencourt, R; Couto, I; Carrilho, L; et al. "Direct application of the INNO-LiPA Rif.TB line-probe assay for rapid identification of Mycobacterium tuberculosis complex strains and detection of rifampin resistance in 360 smear-positive respiratory specimens from an area of high incidence of multidrug-resistant tuberculosis". JOURNAL OF CLINICAL MICROBIOLOGY (2005):
    10.1128/jcm.43.9.4880-4884.2005
  249. Ordway, DJ; Pinto, L; Costa, L; Martins, M; Leandro, C; Viveiros, M; Amaral, L; et al. "Gamma delta T cell responses associated with the development of tuberculosis in health care workers". FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY (2005):
    10.1016/j.femsim.2004.09.005
  250. Marta Martins; Wilfrid Bleiss; Anorte Marko; Diane Ordway; Miguel Viveiros; Clara Leandro; Teresa Pacheco; et al. "Clinical concentrations of thioridazine enhance the killing of intracellular methicillin-resistant Staphylococcus aureus". In Vivo 18 6 (2004): 787-794. https://research.unl.pt/en/publications/clinical-concentrations-of-thioridazine-enhance-the-killing-of-intracellular-methicillinresistant-staphylococcus-aureus(aa321791-8547-499f-b3e4-61f0edc19608).html.
  251. Amaral L; Viveiros M; Molnar J. "Antimicrobial activity of phenothiazines.". In vivo (Athens, Greece) (2004): http://europepmc.org/abstract/med/15646813.
  252. Malthe M. Kristiansen; Clara Leandro; Diane Ordway; Marta Martins; Miguel Viveiros; Teresa Pacheco; Jette E. Kristiansen; Leonard Amaral. "Phenothiazines alter resistance of methicillin-resistant strains of Staphylococcus aureus (MRSA) to oxacillin in vitro". International Journal Of Antimicrobial Agents 22 3 (2003): 250-253. https://research.unl.pt/en/publications/phenothiazines-alter-resistance-of-methicillinresistant-strains-of-staphylococcus-aureus-mrsa-to-oxacillin-in-vitro(580a0a3f-9b63-46a4-96da-d37f37a1b599).html.
    10.1016/s0924-8579(03)00200-0
  253. Diane Ordway; Miguel Viveiros; Clara Leandro; Rosário Bettencourt; Josefina Almeida; Marta Martins; Jette E. Kristiansen; Joseph Molnar; Leonard Amaral. "Clinical concentrations of thioridazine kill intracellular multidrug-resistant Mycobacterium tuberculosis". Antimicrobial Agents and Chemotherapy -Journal- 47 3 (2003): 917-922. https://research.unl.pt/en/publications/clinical-concentrations-of-thioridazine-kill-intracellular-multidrugresistant-mycobacterium-tuberculosis(74b76ec6-a5d5-4967-9a8e-b2cbf8729cdb).html.
    10.1128/aac.47.3.917-922.2003
  254. Ordway, D; Hohmann, J; Viveiros, M; Viveiros, A; Molnar, J; Leandro, C; Arroz, MJ; Gracio, MA; Amaral, L. "Carpobrotus edulis methanol extract inhibits the MDR efflux pumps, enhances killing of phagocytosed S-aureus and promotes immune modulation". PHYTOTHERAPY RESEARCH (2003):
    10.1002/ptr.1314
  255. Viveiros, M; Leandro, C; Amaral, L. "Mycobacterial efflux pumps and chemotherapeutic implications". INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2003):
    10.1016/s0924-8579(03)00208-5
  256. Grácio, M.A.; Dos Santos Grácio, A.J.; Viveiros, M.; Amaral, L.. "Since phenothiazines alter antibiotic susceptibility of microorganisms by inhibiting efflux pumps, are these agents useful for evaluating similar pumps in phenothiazine-sensitive parasites?". International Journal of Antimicrobial Agents 22 3 (2003): 347-351. http://www.scopus.com/inward/record.url?eid=2-s2.0-0042834382&partnerID=MN8TOARS.
    10.1016/s0924-8579(03)00204-8
  257. Diane Ordway; Miguel Viveiros; Clara Leandro; Maria Jorge Arroz; Joseph Molnar; Jette E. Kristiansen; Leonard Amaral. "Chlorpromazine has intracellular killing activity against phagocytosed Staphylococcus aureus at clinical concentrations". Journal of Infection and Chemotherapy 8 3 (2002): 227-231. https://research.unl.pt/en/publications/chlorpromazine-has-intracellular-killing-activity-against-phagocytosed-staphylococcus-aureus-at-clinical-concentrations(20f626b7-be04-42bf-bc20-d9de9b2a9909).html.
    10.1007/s10156-002-0188-4
  258. Ordway, D; Viveiros, M; Leandro, C; Arroz, MJ; Amaral, L. "Intracellular activity of clinical concentrations of phenothiazines including thioridiazine against phagocytosed Staphylococcus aureus". INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2002):
    10.1016/S0924-8579(02)00110-3
  259. Viveiros, M.; Portugal, I.; Bettencourt, R.; Victor, T.C.; Jordaan, A.M.; Leandro, C.; Ordway, D.; Amaral, L.. "Isoniazid-induced transient high-level resistance in Mycobacterium tuberculosis". Antimicrobial Agents and Chemotherapy 46 9 (2002): 2804-2810. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036719989&partnerID=MN8TOARS.
    10.1128/AAC.46.9.2804-2810.2002
  260. Amaral L; Kristiansen JE; Viveiros M; Atouguia J. "Activity of phenothiazines against antibiotic-resistant Mycobacterium tuberculosis: a review supporting further studies that may elucidate the potential use of thioridazine as anti-tuberculosis therapy.". The Journal of antimicrobial chemotherapy (2001): http://europepmc.org/abstract/med/11328759.
    10.1093/jac/47.5.505
  261. Miguel Viveiros; L Amaral; Viveiros, M; Amaral, L. "Enhancement of antibiotic activity against poly-drug resistant Mycobacterium tuberculosis by phenothiazines". International Journal Of Antimicrobial Agents 17 3 (2001): 225-228. https://research.unl.pt/en/publications/enhancement-of-antibiotic-activity-against-polydrug-resistant-mycobacterium-tuberculosis-by-phenothiazines(421d5e73-626f-4e33-9cce-de92d7ecf848).html.
    10.1016/s0924-8579(00)00343-5
  262. Amaral, L.; Viveiros, M.; Kristiansen, J.E.. "Phenothiazines: Potential alternatives for the management of antibiotic resistant infections of tuberculosis and malaria in developing countries". Tropical Medicine and International Health 6 12 (2001): 1016-1022. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035657318&partnerID=MN8TOARS.
    10.1046/j.1365-3156.2001.00804.x
  263. Miguel Viveiros; Suzana Bosne-David; Leonard Amaral. "Comparative in vitro activity of phenothiazines against multidrug- resistant Mycobacterium tuberculosis". International Journal Of Antimicrobial Agents 16 1 (2000): 69-71. https://research.unl.pt/en/publications/comparative-in-vitro-activity-of-phenothiazines-against-multidrug-resistant-mycobacterium-tuberculosis(3a4d1ea2-8f75-4af9-a2bf-c13eb2c5454b).html.
    10.1016/s0924-8579(00)00199-0
  264. Viveiros, M.; Krubasik, P.; Sandmann, G.; Houssaini-Iraqui, M.. "Structural and functional analysis of the gene cluster encoding carotenoid biosynthesis in Mycobacterium aurum A+". FEMS Microbiology Letters 187 1 (2000): 95-101. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034213794&partnerID=MN8TOARS.
    10.1016/S0378-1097(00)00182-8
  265. Miguel Viveiros; S. Pinheiro; Patrícia Raquel Moreira; Teresa Pacheco; Laura Maria Lourenço Brum da Cruz Martins. "Evaluation of a commercial ligase chain reaction assay for the diagnosis of pulmonary and extra-pulmonary tuberculosis". International Journal of Tuberculosis and Lung Disease 3 6 (1999): 508-514. https://research.unl.pt/en/publications/evaluation-of-a-commercial-ligase-chain-reaction-assay-for-the-diagnosis-of-pulmonary-and-extrapulmonary-tuberculosis(f32adb81-01f8-417d-82ca-555f263437d5).html.
  266. Portugal I; Covas MJ; Brum L; Viveiros M; Ferrinho P; Moniz-Pereira J; David H. "Outbreak of multiple drug-resistant tuberculosis in Lisbon: detection by restriction fragment length polymorphism analysis.". The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease (1999): http://europepmc.org/abstract/med/10094321.
  267. Graça Ribeiro; Miguel Viveiros; H. L. David; João V. Costa. "Mycobacteriophage D29 contains an integration system similar to that of the temperate mycobacteriophage L5". Microbiology-Sgm 143 8 (1997): 2701-2708. https://research.unl.pt/en/publications/mycobacteriophage-d29-contains-an-integration-system-similar-to-that-of-the-temperate-mycobacteriophage-l5(9858b247-c6d1-43b9-bbd0-a87dd1f10d8a).html.
    10.1099/00221287-143-8-2701
  268. Emília Prieto; Teresa Pacheco; Miguel Viveiros; Rosário Bettencourt; Laura Brum; Filomena Exposto. "Pesquisa de infecção micobacteriana em hemoculturas de doentes com SIDA, usando o sistema BACTEC 460TB". Revista Portuguesa de Pneumologia 2 6 (1996): 403-407. http://dx.doi.org/10.1016/s0873-2159(15)31178-8.
    10.1016/s0873-2159(15)31178-8
Capítulo de livro
  1. da Silva, PEA; Machado, D; Ramos, D; Couto, I; Von Groll, A; Viveiros, M. "Efflux Pumps in Mycobacteria: Antimicrobial Resistance, Physiological Functions, and Role in Pathogenicity". 2016.
    10.1007/978-3-319-39658-3_21
  2. Miguel Viveiros; Isabel Couto; Joao Inacio. "Diagnóstico Molecular". editado por {Barroso, 182-196. Lidel - Edi{\cc, 2014.
  3. Miguel Viveiros; Isabel Couto; ML, Rossetti; PA, da Silva. "Otimização, validação e controlo de qualidade de testes moleculares de diagnóstico". editado por {Cunha. Lidel - Edi{\cc, 2014.
  4. I, Portugal; Miguel Viveiros. "Mycobacterium". 316-331. Lidel - Edi{\cc, 2014.
  5. Miguel Viveiros; Leonard Amaral; Isabel Couto. "Therapy of the XDR-TB patients with thioridazine - an old drug with new applications.". 232-242. CABI, 2013.
  6. Miguel Viveiros; Isabel Couto; Leonard Amaral. "Improving on the LJ slope: automated liquid culture.". 34-45. CABI, 2013.
  7. Leonard Amaral; Ana Martins; Gabriella Spengler; Marta Martins; Liliana Rodrigues; Matthew McCusker; Eleni Ntokou; et al. "Structure, Genetic Regulation, Physiology and function of the acrab-tolc efflux pump of escherichia coli and salmonella". 44-61. CABI Publishing, 2012.
  8. Leonard Amaral; Séamus Fanning; Gabriella Spengler; L. Rodrigues; C. Iversen; M. Martins; A. Martins; et al. "Genetic regulation, physiology, assessment and inhibition of efflux pumps responsible for multi-drug resistant phenotypes of bacterial pathogens". editado por A Meszaros; G Balogh, 91-116. Nova Science Publishers, Inc., 2012.
  9. Miguel Viveiros. "Segurança em laboratórios de Microbiologia.". 587-609. Edi{\cc, 2010.
  10. Miguel Viveiros; Leonard Amaral; Isabel Couto. "One day identification of the md-rtb patient and proposed novel and effective therapy that is supported by extensive research.". 328 p.-328 p.. Nova science publishers, 2009.
Livro
  1. Armada, A.; Martins, C.; Spengler, G.; Molnar, J.; Amaral, L.; Rodrigues, A.S.; Viveiros, M.. Fluorimetric methods for analysis of permeability, drug transport kinetics, and inhibition of the ABCB1 membrane transporter. 2016.
    10.1007/978-1-4939-3347-1_7
  2. Rodrigues, L.; Viveiros, M.; Aínsa, J.A.. Measuring efflux and permeability in mycobacteria. 2015.
    10.1007/978-1-4939-2450-9_13
  3. Costa, P.; Couto, I.; Viveiros, M.; Inácio, J.. Nested and multiplex real-time PCR using dual-labeled probes: Detecting and discriminating Mycobacterium tuberculosis complex members in cultures and animal tissues. 2014.
    10.1007/978-1-4939-2004-4_9
Poster em conferência
  1. Rodrigues, T; Andrade, Mariana; Marques, Joana; Rodrigues, Liliana; Viveiros, Miguel; Silveira, Henrique; Couto, Isabel; et al. "Implementation of a Galleria mellonella infection model at GHTM/IHMT-NOVA". Trabalho apresentado em Congress of Microbiology and Biotechnology 2023, 2023.
  2. Mariana Pinto; Ana Tavares; Mayreli Ortiz; Vasoula Skouridou; Miriam Jauset-Rubio; Miguel Viveiros; Ciara K. O'Sullivan; et al. Autor correspondente: Ana Lopes Tavares. "Rapid detection of single nucleotide polymorphisms associated with drug resistance in malaria parasites using isothermal amplification approach". Trabalho apresentado em Congresso de Saúde Pública 2023 ¿ Uma Nova Era, 2023.
  3. Ana Lopes Tavares; Miriam Jauset-Rubio; Mayreli Ortiz; Marcelo Urbano Ferreira; Diana Machado; Viveiros, Miguel; Ana Paula Arez; Ciara K. O' Sullivan. "Use of biosensors in the rapid detection of SNPs associated with resistance to antimalarials based on the isothermal amplification strategy". Trabalho apresentado em 6º Congresso Nacional de Medicina Tropical, 2023.
  4. Carolina Ferreira; Patricia Abrantes; Sofia Santos Costa; Miguel Viveiros; Isabel Couto; Carolina Ferreira; Abrantes, Patrícia; et al. "Occurence and variability of norA and other main multidrug efflux pump determinants across the Staphylococcus genus". Trabalho apresentado em European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), 2023.
  5. Ferreira, Carolina; Costa, Sofia Santos; Abrantes, Patrícia; Viveiros, Miguel; Couto, Isabel. "Rapid screening of norA alleles among Staphylococcus aureus strains causing SSTIs in different hosts". Trabalho apresentado em 32nd European Congress on Clinical Microbiology and Infectious Diseases (ECCMID), Lisbon/webconference, 2022.
  6. Carolina Ferreira; Sofia Santos Costa; Patricia Abrantes; Miguel Viveiros; Isabel Couto. "Rapid screening of norA alleles among Staphylococcus aureus strains causing SSTIs in different hosts". 2022.
  7. Bento-Cunha, Renata; Tatiana Vassilevskaia; Rodrigues, L; Viveiros, Miguel; Cunha, Celso. "Repsitioning drugs with potential activity against SARS-CoV-2 infection.". Trabalho apresentado em Microbiotec21, 2021.
  8. Silva, Carla; Antunes, Jessica; Serra, Débora; Toscano, Cristina; Viveiros, Miguel; Machado, Diana. "Detection of ß-lactamases and the simultaneous presence of increased efflux activity in Enterobacteriaceae using a 96-well microplate method.". Trabalho apresentado em MicroBiotec¿21, 2021.
  9. Silva, Carla; Viveiros, Miguel; Machado, Diana. "Optimization of a cost-effective method for the simultaneous detection of carbapenemases and efflux activity in Enterobacteriaceae". Trabalho apresentado em 31st European Congress of Clinical Microbiology & Infectious Diseases (ECCMID), 2021.
  10. Diana Machado; Gothe, Sarah; Martins, Marta C819-2F75-3A0A; Pacheco, Teresa; Batista, Judite; Toscano, Cristina; Viveiros, Miguel. "The emergence of high-level colistin resistance during treatment against heteroresistant Acinetobacter baumannii: a silent cause of treatment failure". Trabalho apresentado em 31st European Congress of Clinical Microbiology & Infectious Diseases (ECCMID), 2021.
  11. Renata Bento Cunha; Tatiana D. Vassilevskaia; Liliana Rodrigues; Miguel Viveiros; Celso Cunha. "Repositioning drugs with potential activity against SARS-CoV-2 infection.". 2021.
  12. Gothe, Sarah; Machado, Diana; Martins, Marta C819-2F75-3A0A; Pacheco, Teresa; Batista, Judite; Toscano, Cristina; Viveiros, Miguel. "Insights on colistin-heteroresistant Acinetobacter baumannii towards the development of effective therapies". Trabalho apresentado em III International Conference NOVAhealth Chronic Disease and Infection: Infection, Cancer and Global Health, 2020.
  13. Roseiro, Isabel; Machado, Diana; Viveiros, Miguel. "Tackling ß-lactam resistance in Escherichia coli ¿ the role of efflux pumps in ß-lactamase producing strains". Trabalho apresentado em NOVAhealth Chronic Disease and Infection "Infection, Cancer and Global Health", 2020.
  14. Diana Machado; Viveiros, Miguel; Pieroni, Marco. "Targeting Mycobacterium tuberculosis membrane energetics with lipophilic efflux inhibitors as adjuvants of tuberculosis treatment". Trabalho apresentado em III International Conference NOVAhealth Chronic Disease and Infection "Infection, Cancer and Global Health", 2020.
  15. Silva, Carla; Machado, Diana; Viveiros, Miguel. "Optimization of a cost-effective method for the simultaneous detection of ß-lactamases and efflux activity in Escherichia coli.". Trabalho apresentado em III International Conference NOVAhealth Chronic Disease and Infection "Infection, Cancer and Global Health", 2020.
  16. Diana Machado; Ravichandran, Rushiil; Machado, Diana; Kroger, Carsten; Viveiros, Miguel; Martins, Marta. "Tackling resistance to carbapenem and colistin in clinical isolates of Acinetobacter baumannii.". Trabalho apresentado em 30th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), 2020.
  17. Liliana Rodrigues; Pedro Cravo; Miguel Viveiros. "Targeting membrane transporters and energy metabolism in Mycobacterium tuberculosis through in silico drug repurposing". 2020.
  18. Rute Ribeiro; Sofia Santos Costa; Constança Pomba; Miguel Viveiros. "Biocide and antibiotic resistance in Staphylococcus aureus causing skin and soft tissue infections in companion animals". 2019.
  19. Sofia Santos Costa; Patricia Abrantes; C Morais; Miguel Viveiros; Adriana E. Rosato; Isabel Couto. "Exploring the staphylococcal efflux-mediated response to ethidium bromide, an efflux pump substrate". 2019.
  20. Sofia Santos Costa; SS Costa; S Santos Costa; Abrantes, Patrícia; Morais, Catarina; Viveiros, Miguel; Rosato, Adriana; Couto, Isabel. "Exploring the efflux-mediated multidrug resistance in staphylococci". Trabalho apresentado em National Congress of Microbiology and Biotechnology (MicroBiotec19). Coimbra, Portugal, 2019.
  21. Pereira, Bruna 5D1E-C298-769E; Machado, Diana; Silva, Carla; Viveiros, Miguel. "Exploring the contribution of efflux on the resistance to antibiotics, biocidesand dyes in clinical isolates of Escherichia coli". Trabalho apresentado em MicroBiotec¿19, 2019.
  22. Machado, Diana; Neves, Iolanda; Silva, Carla; Viveiros, Miguel. "Tackling bacterial infections by eliminating persister cells with efflux inhibitors.". Trabalho apresentado em MicroBiotec¿19, 2019.
  23. Machado, Diana; Pedrosa, Pedro; Piedade, João; Baptista, Pedro V.; Viveiros, Miguel. "Application of superparamagnetic nanoparticles for the early diagnosis of tuberculosis and HIV co-infection directly from respiratory samples.". Trabalho apresentado em Congresso Nacional de Microbiologia e Biotecnologia (MicroBiotec19), 2019.
  24. Maia, Inês; Machado, Diana; Viveiros, Miguel. "Evaluation of competition between substrates of the efflux pump system AcrAB-TolC of Escherichia coli using Red Nile.". Trabalho apresentado em Congresso Nacional de Microbiologia e Biotecnologia (MicroBiotec19), 2019.
  25. Roseiro, Isabel; Machado, Diana; Viveiros, Miguel. "The dark-side of drug resistance in Escherichia coli: efflux pumps and ß-lactamase producing strains.". Trabalho apresentado em Congresso Nacional de Microbiologia e Biotecnologia (MicroBiotec19), 2019.
  26. Ôchoa-Pires, Tiago; Froufe, Hugo; Barroso, Cristina; Machado, Diana; Rosa, Marguerita; Laranjeira, João; Seabra, Rafaela; et al. "Exploring Japanese quail immune repertoires for antibody discovery.". Trabalho apresentado em Congresso Nacional de Microbiologia e Biotecnologia (MicroBiotec19), 2019.
  27. Ribeiro, José; Machado, Diana; Viveiros, Miguel. "A bioinformatic approach to understand antibiotic resistance due to small multidrug resistant (SMR)-type efflux pumps in Acinetobacter baumannii through whole genome analysis.". Trabalho apresentado em Congresso Nacional de Microbiologia e Biotecnologia (MicroBiotec19), 2019.
  28. Tavares, Ana M.; Pingarilho, Marta; Batista, Judite; Toscano, Cristina; Dias, Sónia; Gomes, Perpétua; Viveiros, Miguel; Abecasis, Ana B.. "Sociodemographic and clinical characteristics of migrants and natives with HIV-TB co-infection in Portugal.". Trabalho apresentado em Ciência 2018, 2019.
  29. Machado, Diana; Pedrosa, Pedro; Piedade, João; Baptista, Pedro V.; Viveiros, Miguel. "Application of superparamagnetic nanoparticles for fast, simultaneous and non-invasive diagnosis of tuberculosis and HIV infection.". Trabalho apresentado em 40th Annual Congress of the European Society of Mycobacteriology, 2019.
  30. Sofia Santos Costa; Patricia Abrantes; C Morais; Miguel Viveiros; Isabel Couto. "Exploring the efflux-driven multidrug resistance in staphylococci". 2019.
  31. Machado, Diana; Azzali, Elisa; Couto, Isabel; Constantino, Gabriele; Pieroni, Marco; Viveiros, Miguel. "Adjuvant therapies against tuberculosis: discovery of a 2-aminothiazole targeting Mycobacterium tuberculosis energetics.". Trabalho apresentado em Multi-drug efflux systems: Gordon Research Conferences, 2019.
    10.2217/fmb-2018-0110
  32. Machado, Diana; Costa, Raquel; Neves, Iolanda; Antunes, Jéssica; Couto, Isabel; Viveiros, Miguel. "Contribution of efflux to the emergence of antibiotic resistance in persister cells.". Trabalho apresentado em 28th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), 2019.
  33. Ramos, Jorge; Machado, Diana; Couto, Isabel; Viveiros, Miguel. "Diagnóstico laboratorial de micobactérias no Instituto de Higiene e Medicina Tropical: retrospetiva dos últimos 5 anos". Trabalho apresentado em 4º Congresso Nacional de Medicina Tropical, 2019.
  34. Theron, Maria; Machado, Diana; Couto, Isabel; Viveiros, Miguel. "Determination of efflux activity of Hoechst 33258 in Escherichia coli using a 96-well plate fluorescence assay.". Trabalho apresentado em NOVAsaude IV Genetics Workshop, 2019.
  35. Rodrigues, Fátima; Machado, Diana; Antunes, Jéssica; Couto, Isabel; Pacheco, teresa; Batista, Judite; Toscano, Cristina; Viveiros, Miguel. "Colistin resistance in Acinetobacter baumannii: correlation between mutations in target genes and active efflux.". Trabalho apresentado em NOVAsaude IV Genetics Workshop, 2019.
  36. Ribeiro, José; Machado, Diana; Antunes, Jéssica; Rodrigues, Fátima; Couto, Isabel; Pacheco, teresa; Batista, Judite; Toscano, Cristina; Viveiros, Miguel. "Prevalence of genes encoding small multidrug resistant (SMR)-type efflux pumps in Acinetobacter baumannii resistant to carbapenems isolated in hospital environment.". Trabalho apresentado em NOVAsaude IV Genetics Workshop, 2019.
  37. Neves, Iolanda; Machado, Diana; Costa, Raquel; Antunes, Jéssica; Mendes, Ângela; Castro, Rita; Couto, Isabel; Viveiros, Miguel. "Persister cells survive antibiotic treatment mounting an active response via activation of efflux pumps.". Trabalho apresentado em NOVAsaude IV Genetics Workshop., 2019.
  38. Machado, Diana; Perdigão, João; Ramos, Jorge; Tavares, Ana Maria; Abecasis, Ana; Dias, Sonia; Clark, Taane G.; et al. "Molecular epidemiology of antibiotic resistance genes in multi- and extensively drug-resistant Mycobacterium tuberculosis in Lisbon and its correlation with drug resistance levels". Trabalho apresentado em NOVAsaude IV Genetics Workshop, 2019.
  39. Liliana Rodrigues; Pedro Cravo; Miguel Viveiros. "Chemogenomics and in silico repurposing as an innovative approach for rapid drug discovery in tuberculosis.". 2019.
  40. Sofia Santos Costa; Mafalda Rosa; Frederico Holtreman; Ana Catarina Rodrigues; Miguel Viveiros; Constança Pomba; Isabel Couto. "Emergence of non-wild-type populations towards biocides in Staphylococcus epidermidis colonizing veterinary staff". 2018.
  41. Sofia Santos Costa; Adriana E. Rosato; Miguel Viveiros; Isabel Couto. "Development of multidrug resistance in staphylococci driven by efflux". 2018.
  42. Sofia Santos Costa; Mafalda Rosa; Adriana Belas; Miguel Viveiros; Constança Pomba; Isabel Couto. "Biocide susceptibility in Staphylococcus epidermidis causing infection in pets". 2018.
  43. Sofia Santos Costa; Cláudia Mineiro Santos; Miguel Viveiros; Constança Pomba. "Frequent biofilm production by Staphylococcus epidermidis causing infection in pets or colonizing veterinary staff". 2018.
  44. Costa, Sofia Santos ; Kadlec, Kristina; Viveiros, Miguel; Melo-Cristino, José; Schwarz, Stefan; Couto, Isabel. "Complete sequences of two plasmids carrying genes for resistance to antibiotics, heavy-metals, biocides and/or virulence". Trabalho apresentado em 18th International Symposium of Staphylococci and Staphylococcal Infections (ISSSI), Copenhagen, Denmark, 2018.
  45. Costa, Sofia Santos ; Santos, Cláudia Mineiro; Viveiros, Miguel; Pomba, Constança; Couto, Isabel. "Frequent biofilm production by Staphylococcus epidermidis causing infections in pets or colonizing veterinary staff". Trabalho apresentado em 18th International Symposium of Staphylococci and Staphylococcal Infections (ISSSI), Copenhagen, Denmark, 2018.
  46. Costa, Sofia Santos ; Rosa, Mafalda; Holtreman, Frederico; Rodrigues, Ana Catarina; Viveiros, Miguel; Pomba, Constança; Couto, Isabel. "Emergence of non-wild-type populations towards biocides in Staphylococcus epidermidis colonizing veterinary staff". Trabalho apresentado em 18th International Symposium of Staphylococci and Staphylococcal Infections (ISSSI), Copenhagen, Denmark, 2018.
  47. Costa, Sofia Santos ; Rosa, Mafalda; Belas, Adriana; Viveiros, Miguel; Pomba, Constança; Couto, Isabel. "Biocide susceptibility in Staphylococcus epidermidis causing infections in pets". Trabalho apresentado em 18th International Symposium of Staphylococci and Staphylococcal Infections (ISSSI), Copenhagen, Denmark, 2018.
  48. Tavares, Ana M.; Fronteira, Inês; Couto, Isabel; Machado, Diana; Viveiros, Miguel; Abecasis, Ana B.; Dias, Sónia. "HIV and tuberculosis co-infection among migrants in Europe: a systematic review". Trabalho apresentado em Ciência 2018, 2018.
  49. Costa, Sofia Santos; Lopes, Elizeth; Pieroni, Marco; Machado, Diana; Costantino, Gabriele; Viveiros, Miguel; Couto, Isabel. "Mycobacterium smegmatis model for the rapid screening of new compounds with efflux inhibitory activity and antimycobacterial activity". Trabalho apresentado em 1st Symposium of Tuberculosis and Non-tuberculous mycobacteria. Coimbra, Portugal, 2018.
  50. Perdigão, João; Silva, Carla; Diniz, Jaciara; Pereira, Catarina; Machado, Diana; Ramos, Jorge; Silva, Hugo; et al. "CPLP-TB: a novel framework and surveillance tool for tracing Mycobacterium tuberculosis strains across Lusophone countries.". Trabalho apresentado em 1º Simpósio de Investigação em Tuberculose e Micobactérias Não Tuberculosas em Portugal., 2018.
  51. Sofia Santos Costa; Mafalda Rosa; Ana Catarina Rodrigues; Cláudia Mineiro Santos; Frederico Holtreman; Miguel Viveiros; Constança Pomba; Isabel Couto. "Characterization of antimicrobial resistance in Staphylococcus epidermidis colonizing veterinary staff and students". 2017.
  52. Frederico Holtreman; Sofia Santos Costa; Mafalda Rosa; Miguel Viveiros; Constança Pomba; Isabel Couto. "Characterization of plasmid encoded efflux determinants from Staphylococcus epidermidis". 2017.
  53. Cláudia Mineiro Santos; Sofia Santos Costa; Miguel Viveiros; Constança Pomba; Isabel Couto. "Prevalence of biofilm production in Staphylococcus epidermidis colonizing veterinary staff and students". 2017.
  54. Brandão, Ângela; Machado, Diana; Pinhata, Juliana; Oliveira, Rosangela; Ferrazoli, Lucilaine; Chimara, Erica; Viveiros, Miguel. "Reliability of a multiplex allele-specific polymerase chain reaction (MAS-PCR) for the detection of multidrug-resistant Mycobacterium tuberculosis clinical isolates from Brazil.". Trabalho apresentado em Congresso Nacional de Microbiologia e Biotecnologia (MicroBiotec17), 2017.
  55. Antunes, Jéssica; Machado, Diana; Couto, Isabel; Pacheco, teresa; Batista, Judite; Toscano, Cristina; Viveiros, Miguel. "Correlation between carbapenem resistance, ß-lactamases, porins and efflux pumps in Acinetobacter baumannii clinical isolates.". Trabalho apresentado em Congresso Nacional de Microbiologia e Biotecnologia (MicroBiotec17), 2017.
  56. Laranjeira, João; Rosa, Marguerita; Machado, Diana; Francisco, Rafael; Viveiros, Miguel; Vieira-Pires, Ricardo. "Fighting bacterial infections with avian IgY antibodies.". Trabalho apresentado em Congresso Nacional de Microbiologia e Biotecnologia (MicroBiotec17), 2017.
  57. Silva, Mariana; Machado, Diana; Ramos, Jorge; Couto, Isabel; Viveiros, Miguel. "The contribution of efflux to ß-lactams resistance in non-ESBL-producing Escherichia coli clinical isolates". Trabalho apresentado em MicroBiotec17, 2017.
  58. Silva, Mariana; Machado, Diana; Ramos, Jorge; Couto, Isabel; Viveiros, Miguel. "The interplay between efflux and ß-lactamase activity in ß-lactams resistance in non-ESBLproducing Escherichia coli clinical isolates". Trabalho apresentado em NOVAsaude III Genetics Workshop, 2017.
  59. Moisés Francisco; Sofia Santos Costa; Adriana Belas; Jorge Ramos; Isabel Couto; Constança Pomba; Miguel Viveiros; et al. "Antimicrobial resistance and molecular characterization of Salmonella enterica serotype Typhi isolated in Luanda, Angola, in human specimens during 2013-2014". Trabalho apresentado em VIII Scientific Day of IHMT-NOVA. Lisbon, Portugal, 2017.
  60. Isabel Couto; Sofia Santos Costa; Miguel Viveiros; Constança Pomba. "NorA mediated efflux in Staphylococcus epidermidis". 2017.
  61. Mafalda Rosa; Sofia Santos Costa; Miguel Viveiros; Constança Pomba; Isabel Couto. "Contribuição do efluxo para a resistência a compostos antimicrobianos em Staphylococcus epidermidis". 2017.
  62. Frederico Holtreman; Sofia Santos Costa; Mafalda Rosa; Miguel Viveiros; Constança Pomba; Isabel Couto. "Influência do efluxo na resistência a antibióticos e suscetibilidade reduzida aos biocidas em Staphylococcus epidermidis". 2017.
  63. Karen Mattos; Sofia Santos Costa; Isabel Couto; Carlos Emílio Levy; Cátia Marques; Patrícia Moriel; Constança Pomba; Miguel Viveiros. "Epidemiologia molecular e caracterização genética de estirpes de Klebsiella pneumoniae multirresistentes provenientes de um Hospital Universitário no Brasil". 2017.
  64. Cláudia Mineiro Santos; Sofia Santos Costa; Miguel Viveiros; Constança Pomba; Isabel Couto. "Correlação da produção de biofilme com a actividade de efluxo e resistência a antimicrobianos em Staphylococcus epidermidis". 2017.
  65. Machado, Diana; Coelho, Tatiane; Perdigão, João; Pereira, Catarina; Couto, Isabel; Portugal, Isabel; Maschmann, Raquel; et al. "Correlação entre a presença de mutações e a actividade de efluxo em isolados clínicos de Mycobacterium tuberculosis resistente aos antibióticos.". Trabalho apresentado em 3o Congresso Nacional de Medicina Tropical, 2017.
  66. Silva, Mariana; Machado, Diana; Couto, Isabel; Viveiros, Miguel. "A contribuição do efluxo na resistência aos ß-lactâmicos em Escherichia coli.". Trabalho apresentado em 3o Congresso Nacional de Medicina Tropical, 2017.
  67. Antunes, Jéssica; Machado, Diana; Couto, Isabel; Pacheco, teresa; Batista, Judite; Toscano, Cristina; Viveiros, Miguel. "Caracterização fenotípica e relação clonal entre isolados clínicos de Acinetobacter baumannii resistentes aos carbapenemos.". Trabalho apresentado em 3o Congresso Nacional de Medicina Tropical. Lisbon, Portugal, 2017.
  68. Costa, Raquel; Machado, Diana; Couto, Isabel; Viveiros, Miguel. "Estudo do efeito de fontes de carbono e inibidores de efluxo na susceptibilidade aos antibióticos em Escherichia coli.". Trabalho apresentado em 3º Congresso Nacional de Medicina Tropical, 2017.
  69. Sofia Santos Costa; Miguel Viveiros; Constança Pomba; Isabel Couto. "The role of efflux systems on antimicrobial resistance development in Staphylococcus epidermidis". 2017.
  70. Laranjeira, João; Machado, Diana; Francisco, Rafael; Rosa, Marguerita; Viveiros, Miguel; Vieira-Pires, Ricardo. "An avian antibody platform to fight bacterial infections.". Trabalho apresentado em 3rd Biologics and Biosimilars Congress, 2017.
  71. Diniz, Jaciara de Lourdes do Carmo Guimarães; Ramis I.; Abilleira, F.; Brum, C.; von Groll, A.; Silva A.; Ramos D.; et al. "Insights from the molecular epidemiological analysis of tuberculosis relapse cases in Rio Grande do Sul, Brazil". Trabalho apresentado em 27th ECCMID, 2017.
  72. Diniz, Jaciara de Lourdes do Carmo Guimarães; Perdigão, João; Ramos D.; Campino, S.; Viveiros, Miguel; McNerney, R.; Pain, A.; et al. "Whole-genome sequencing enables differentiation of tuberculosis reinfection with strains bearing the same genotypic patterns". Trabalho apresentado em 27th ECCMID, 2017.
  73. Marrinhas, Carla; Santos, Marta; Marcos, Ricardo; Miranda, Sónia; Fernandes, Laura; Rodrigues, Catarina; Machado, Diana; Viveiros, Miguel; Pomba, Constança. "Infecção por Mycobacterium avium num gato em Portugal.". Trabalho apresentado em 7º Encontro de Formação da Ordem dos Médicos Veterinários, 2016.
  74. Tommaso Felicetti; Rolando Cannalire; Giuseppe Manfroni; Oriana Tabarrini; Diana Machado; Isabel Couto; Sofia Santos Costa; et al. "Natural isoflavone biochanin-A as a template for the design of new and potent 3-phenylquinolone inhibitors of the nontuberculous mycobacteria efflux pumps". 2016.
  75. Perdigão, João; Maltez, Fernando; Machado, Diana; Silva, Hugo; Pereira, Catarina; Silva, Carla; Couto, Isabel; Viveiros, Miguel; Portugal, Isabel. "Extensively drug resistant Tuberculosis plus linezolid resistance: the first report of linezolid resistance development in Lisbon, Portugal.". Trabalho apresentado em 8th iMed.ULisboa Postgraduate Students Meeting and 1st I3DU Meeting., 2016.
  76. Perdigão, João; Clemente, Sofia; Ramos, Jorge; Masakidi, Pedro; Machado, Diana; Silva, Carla; Couto, Isabel; et al. "First Insights on the Drug resistance and Genetic Diversity of Mycobacterium tuberculosis in Luanda, Angola". Trabalho apresentado em 26th ECCMID, 2016.
  77. Sofia Santos Costa; Adriana Belas; Natacha Couto; Catarina Rodrigues; Miguel Viveiros; Constança Pomba; Isabel Couto. "Biocide susceptibility profiles of staphylococci colonizing humans in close contact with pets". 2015.
  78. Machado, Diana; Couto, Isabel; Viveiros, Miguel. "Drug susceptibility testing for Mycobacterium avium complex strains using the MGIT960 system and the TB-eXIST software.". Trabalho apresentado em Congresso de Microbiologia e Biotecnologia (MicroBiotec15), 2015.
  79. Machado, Diana; Serra, Carlos; Viveiros, Miguel; Couto, Isabel. "Characterization of the mechanism of action of efflux inhibitors on the mycobacterial respiratory chain.". Trabalho apresentado em Congresso de Microbiologia e Biotecnologia (MicroBiotec15), 2015.
  80. Rabna, Paulo; Ramos, Jorge; Ponce, Gema; Sanca, Lilica; Mané, Morto; Armada, Ana; Machado, Diana; et al. "Laboratory fast direct detection and characterization of multi and poly drug-resistant tuberculosis in Guinea-Bissau". Trabalho apresentado em 3º Congresso Nacional de Medicina Tropical. Instituto de Higiene e Medicina Tropical, 2015.
  81. Dalla Costa, E.R.; Vasconcelos S.; Esteves, L.; Gomes H.; Gomes L.; Silva PA; Perdigão, João; et al. "Misclassification by Spoligotyping: Multidrug Resistant Mycobacterium tuberculosis of the Latin American Mediterranean Lineage Wrongly Identified as Mycobacterium pinnipedii (ST863)". Trabalho apresentado em Congress of the European Society of Mycobacteriology, 2015.
  82. Coelho, Tatiane; Machado, Diana; Machmann, Raquel; von Groll, Andrea; Rossetti, Maria L; da Silva, Pedro E. Almeida; Viveiros, Miguel. "Efluxo como mecanismo envolvido na resistência antimicrobiana em isolados clínicos de Mycobacterium tuberculosis.". Trabalho apresentado em VII meeting of the Latino-American Society of Tuberculosis and other Mycobacteriosis, 2014.
  83. Sofia Santos Costa; Miguel Viveiros; Josè Melo-Cristino; Isabel Couto. "The role of efflux in the development of multidrug resistance phenotypes in Staphylococcus aureus". 2014.
  84. Sofia Santos Costa; Miguel Viveiros; Josè Melo-Cristino; Isabel Couto. "Impact of active efflux in the development of MDR phenotypes in Staphylococcus aureus". 2014.
  85. Machado, Diana; Silva, Vânia; Couto, Isabel; Ramos, Jorge; Viveiros, Miguel. "The interplay between mutations and efflux in acquired resistance to clarithromycin in Mycobacterium avium complex". Trabalho apresentado em 24th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), 2014.
  86. Rita Branquinho; Salomé Moço; Sofia Santos Costa; Isabel Couto; Miguel Viveiros; Rodrigo Martins; Elvira Fortunato. "Low cost paper-based materials functionalized with nanoparticles for antibacterial applications". 2014.
  87. Sofia Santos Costa; Miguel Viveiros; Josè Melo-Cristino; Isabel Couto. "Efflux as a first-line response to fluoroquinolones and other antimicrobials in Staphylococcus aureus". 2013.
  88. Sofia Santos Costa; Miguel Viveiros; Josè Melo-Cristino; Isabel Couto. "Characterization of a multiresistance plasmid from a methicillin-resistant Staphylococcus aureus clinical strain". 2013.
  89. Cláudia Palma; Sofia Santos Costa; Miguel Viveiros; Josè Melo-Cristino; Isabel Couto. "The role of plasmid determinants in the resistance of Staphylococcus aureus to antimicrobial agents". 2013.
  90. Serra, Carlos; Fernandes, Ana; Machado, Diana; Viveiros, Miguel; Salgueiro, Carlos; Couto, Isabel. "The role of type-II NADH-menaquinone oxidoreductase (NDH-2) on Mycobacterium tuberculosis resistance to drugs.". Trabalho apresentado em Congresso de Microbiologia e Biotecnologia (MicroBiotec13), 2013.
  91. Silva, Vânia; Machado, Diana; Ramos, Jorge; Couto, Isabel; Viveiros, Miguel. "Contribution of efflux systems to clarithromycin resistance in Mycobacterium avium complex.". Trabalho apresentado em MicroBiotec13, 2013.
  92. Machado, Diana; Perdigão, João; Ramos, Jorge; Couto, Isabel; Portugal, Isabel; Viveiros, Miguel; Ramos, J.; Couto, I.; Portugal, I.. "Correlation between phenotypic and genetic resistance to first and second line antituberculosis drugs in a high tuberculosis endemic area". Trabalho apresentado em MicroBiotec13, 2013.
  93. Machado, Diana; Couto, Isabel; Ramos, Jorge; Viveiros, Miguel. "Contribution of efflux pumps to overall antibiotic resistance in Mycobacterium tuberculosis and the usefulness of efflux inhibitors as ¿helper compounds¿ in drug therapy". Trabalho apresentado em 23rd European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), 2013.
  94. Pedrosa, Pedro; Viegas, Bruno; Machado, Diana; Perdigão, João; Portugal, Isabel; Couto, Isabel; Viveiros, Miguel; Baptista, Pedro V.. "Gold nanoprobes methodology for diagnosis of multi-drug resistant tuberculosis.". Trabalho apresentado em NanoPT, 2013.
  95. Sofia Santos Costa; Miguel Viveiros; Isabel Couto. "Relevância clínica de sistemas de efluxo na resistência a compostos antimicrobianos em Staphylococcus aureus". 2012.
  96. Gröblacher, Barbara; Armada, Ana; Machado, Diana; Viveiros, Miguel; Bucar, Franz. "Mycobacterial efflux inhibitors from Aframomum melegueta.". Trabalho apresentado em II International Conference on Antimicrobial Research (ICAR), 2012.
  97. Machado, Diana; Couto, Isabel; Ramos, Jorge; Viveiros, Miguel. "Efflux inhibitors as adjuvants in drug resistant tuberculosis therapy". Trabalho apresentado em EMBO Conference: Tuberculosis 2012: Biology, pathogenesis, intervention strategies, 2012.
  98. Cláudia Mourato; Sofia Santos Costa; Miguel Viveiros; Leonard Amaral; Josè Melo-Cristino; Isabel Couto. "Co-resistance to biocides and beta-lactams in a MRSA clinical isolate". 2012.
  99. Sofia Santos Costa; Miguel Viveiros; Leonard Amaral; Patrick Butaye; Isabel Couto. "Susceptibility profiles of antibiotics, biocides and dyes in Staphylococcus aureus from pigs: correlation with efflux activity". 2012.
  100. Sofia Santos Costa; Miguel Viveiros; Leonard Amaral; Josè Melo-Cristino; Isabel Couto. "Efflux-mediated resistance to quaternary ammonium compounds in methicillin resistant Staphylococcus aureus (MRSA) clinical isolates". 2012.
  101. Mourato, Cláudia; Costa, Sofia Santos; Viveiros, Miguel; Amaral, Leonard; Melo-Cristino, José; Couto, Isabel. "Co-resistance to biocides and beta-lactams in a methicillin-resistant Staphylococcus aureus (MRSA) clinical isolate". Trabalho apresentado em 15th International Symposium on Staphylococci and Staphylococcal Infections (ISSSI), 2012.
  102. Sofia Santos Costa; Cláudia Mourato; Miguel Viveiros; Josè Melo-Cristino; Leonard Amaral; Isabel Couto. "Resistance to biocides conveyed by efflux pumps in clinical isolates of MRSA". 2012.
  103. Sofia Santos Costa; Miguel Viveiros; Leonard Amaral; Isabel Couto. "The role of NorA in the adaptative response of Staphylococcus aureus to stress stimuli". 2012.
  104. Costa, Sofia Santos; Mourato, Cláudia; Viveiros, Miguel; Melo-Cristino, José; Amaral, Leonard; Couto, Isabel. "Resistance to biocides in clinical MRSA isolates conveyed by efflux pumps". Trabalho apresentado em 22nd European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), 2012.
  105. Machado, Diana; Rodrigues, Liliana; Couto, Isabel; Amaral, Leonard; Viveiros, Miguel. "The emergence of clarithromycin resistance in Mycobacterium avium complex.". Trabalho apresentado em 22nd European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), 2012.
  106. Sofia Santos Costa; Cláudia Mourato; Miguel Viveiros; Josè Melo-Cristino; Isabel Couto; Leonard Amaral. "Description of a novel staphylococcal pC194-family plasmid carrying the smr efflux pump gene". 2011.
  107. PINTO Antónia Rosa Trindade; Diana Machado; Sofia Santos Costa; Isabel Couto; Leonard Amaral; Miguel Viveiros. "Multidrug resistance mediated by active efflux in Escherichia coli". 2011.
  108. Cláudia Mourato; Sofia Santos Costa; Miguel Viveiros; Celeste Falcão; Josè Melo-Cristino; Leonard Amaral; Isabel Couto. "Multidrug resistance in a methicillin-resistant Staphylococcus aureus (MRSA) clinical isolate mediated by efflux pump QacA". 2011.
  109. Mourato, Cláudia; Costa, Sofia Santos; Viveiros, Miguel; Falcão, Celeste; Melo-Cristino, José; Amaral, Leonard; Couto, Isabel. "Multidrug resistance in a methicillin-resistant Staphylococcus aureus (MRSA) clinical isolate mediated by efflux pump QacA". Trabalho apresentado em National Congress of Microbiology and Biotechnology (MicroBiotec11). Braga, Portugal, 2011.
  110. Costa, Sofia Santos; Viveiros, Miguel; Amaral, Leonard; Couto, Isabel. "The role of NorA in the adaptative response of Staphylococcus aureus to stress stimuli". Trabalho apresentado em National Congress of Microbiology and Biotechnology (MicroBiotec11). Braga, Portugal, 2011.
  111. Costa, Sofia Santos; Mourato, Cláudia; Viveiros, Miguel; Melo-Cristino, José; Couto, Isabel. "Description of a novel staphylococcal pC194-family plasmid carrying the smr efflux pump gene". Trabalho apresentado em National Congress of Microbiology and Biotechnology (MicroBiotec11). Braga, Portugal, 2011.
  112. Pinto, Antónia; Machado, Diana; Costa, Sofia S; Couto, Isabel; Amaral, Leonard; Viveiros, Miguel; Pinto, Antónia; Machado, Diana; Costa, Sofia Santos . "Multidrug resistance mediated by active efflux in Escherichia coli: new therapeutic strategies using antibiotics and inhibitors of active efflux.". Trabalho apresentado em Congresso de Microbiologia e Biotecnologia (MicroBiotec11), 2011.
  113. Francisco, Samuel; Machado, Diana; Viveiros, Miguel; Ramos, Jorge; Pacheco, Teresa; Melo Cristino, José; Lito, Luís Marques; et al. "Application of molecular methods for the direct detection of MDR-TB". Trabalho apresentado em MicroBiotec11, 2011.
  114. Costa, Sofia Santos; Mourato, Cláudia; Viveiros, Miguel; Melo-Cristino, José; Amaral, Leonard; Couto, Isabel. "Description of a novel pC194-family plasmid carrying the smr efflux pump gene". Trabalho apresentado em 51st Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC). Chicago, USA, 2011.
  115. Cerca, Pedro; Machado, Diana; Viveiros, Miguel; Amaral, Leonard; Couto, Isabel. "Identification of nontuberculous mycobacteria: comparison of three in-house molecular protocols.". Trabalho apresentado em 51st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), 2011.
  116. Sofia Santos Costa; Cláudia Mourato; Miguel Viveiros; Josè Melo-Cristino; Isabel Couto; Leonard Amaral. "Description of a novel pC194-family plasmid carrying the smr efflux pump gene". 2011.
  117. Machado, Diana; Couto, Isabel; Rodrigues, Liliana; Amaral, Leonard; Viveiros, Miguel. "Efflux activity in Mycobacterium tuberculosis as an intrinsic mechanism of resistance to isoniazid.". Trabalho apresentado em 32nd Annual Congress of the European Society of Mycobacteriology, 2011.
  118. Machado, Diana; Couto, Isabel; Amaral, Leonard; Portugal, Isabel; Baptista, Pedro V.; Viveiros, Miguel. "Selection for mutator phenotypes in Mycobacterium tuberculosis.". Trabalho apresentado em 32nd Annual Congress of the European Society of Mycobacteriology, 2011.
  119. Machado, Diana; Couto, Isabel; Rodrigues, Liliana; Perdigão, João; Portugal, Isabel; Amaral, Leonard; Viveiros, Miguel. "Phenotypic adaptation to isoniazid in Mycobacterium tuberculosis: a pathway to multidrug resistant tuberculosis.". Trabalho apresentado em 21st European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), 2011.
  120. Rodrigues, Liliana; Machado, Diana; Couto, Isabel; Amaral, Leonard; Viveiros, Miguel. "Contribution of efflux activity to isoniazid resistance in Mycobacterium tuberculosis complex.". Trabalho apresentado em 21st European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), 2011.
  121. Raúl Saraiva; Sofia Santos Costa; Isabel Couto; Miguel Viveiros; Maria José Feio; Paula Gameiro. "The role of enrofloxacin-based-metallocomplexes in the war against bacterial resistance". 2010.
  122. Viegas, Bruno; Machado, Diana; Perdigão, João; Portugal, Isabel; Couto, Isabel; Viveiros, Miguel; Baptista, Pedro V.. "A PCR-Au-nanoprobes combined approach for detection of mutations associated with antibiotic resistance in Mycobacterium tuberculosis.". Trabalho apresentado em 11th Trends in Nanotechnology International Conference (TNT2010), 2010.
  123. Sofia Santos Costa; Miguel Viveiros; Celeste Falcão; Josè Melo-Cristino; Leonard Amaral; Isabel Couto; Costa, Sofia Santos; et al. "Genetic diversity of the Staphylococcus aureus efflux pump gene norA". Trabalho apresentado em National Congress of Microbiology (Micro09). Vilamoura, Portugal, 2010.
  124. Ramos, Jorge; Machado, Diana; Couto, Isabel; Amaral, Leonard; Viveiros, Miguel. "Evaluation of the BD MGIT¿ TBc identification test for the rapid detection of Mycobacterium tuberculosis complex from cultures". Trabalho apresentado em 31th Annual Congress of the European Society of Mycobacteriology, 2010.
  125. Costa, Sofia Santos; Falcão, Celeste; Viveiros, Miguel; Melo-Cristino, José; Amaral, Leonard; Couto, Isabel; Sofia S. Costa; et al. "Importance of efflux systems on the resistance to fluoroquinolones in Staphylococcus aureus". Trabalho apresentado em 20th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID). Vienna, Austria, 2010.
  126. MARTINS Marta Sofia Lopes; Miguel Viveiros; Isabel Couto; Sofia Santos Costa; Teresa Pacheco; Leonard Amaral. "New method for the rapid screening of efflux pump activity in multi-drug resistant clinical strains". 2009.
  127. Cerca, Pedro; Machado, Diana; Viveiros, Miguel; Amaral, Leonard; Couto, Isabel. "Identification of non-tuberculous mycobacteria by molecular methods: comparison of three in-house protocols.". Trabalho apresentado em Congresso de Microbiologia e Biotecnologia (MicroBiotec09), 2009.
  128. Rodrigues, Liliana; Sampaio, Daniela; Couto, Isabel; Machado, Diana; Kern, Winfried V.; Amaral, Leonard; Viveiros, Miguel. "The role played by efflux pump in macrolide resistance in Mycobacterium avium complex.". Trabalho apresentado em Congresso de Microbiologia e Biotecnologia (MicroBiotec09), 2009.
  129. Ramos, Jorge; Rodrigues, Liliana; Couto, Isabel; Amaral, Leonard; Viveiros, Miguel. "The effect of efflux pumps inhibitors on the transport of ethidium bromide and antimicrobials across Mycobacterium smegmatis cell wall". Trabalho apresentado em Microbiotec09, 2009.
  130. Couto, Isabel; Machado, Diana; Viveiros, Miguel; Rodrigues, Liliana; Amaral, Leonard. "Identification of nontuberculous mycobacteria in clinical samples using molecular methods: a three-year study.". Trabalho apresentado em 30th Annual Congress of the European Society of Mycobacteriology, 2009.
  131. Ramos, Jorge; Rodrigues, Liliana; Couto, Isabel; Amaral, Leonard; Viveiros, Miguel. "Methods for assessment of ethidium bromide transport across Mycobacterium smegmatis cell wall". Trabalho apresentado em 30th Annual congress of European Society of Mycobacteriology, 2009.
  132. Veigas, B.; Perdigão, João; Portugal, I.; Couto, I.; Viveiros, Miguel; Baptista, P.. "Use of Au-nanoprobes for the detection of SNPs associated with antibiotic resistance in Mycobacterium tuberculosis". Trabalho apresentado em MicroBiotec09, 2009.
  133. Couto, Isabel; Viveiros, Miguel; Machado, Diana; Rodrigues, Liliana; Amaral, Leonard. "Identificação de micobactérias atípicas em amostras clínicas utilizando métodos moleculares.". Trabalho apresentado em IX Congresso Nacional de Doenças Infecciosas e Microbiologia Clínica, Sida e Parasitologia, 2008.
  134. Rodrigues, Liliana; Viveiros, Miguel; Sampaio, Daniela; Couto, Isabel; Machado, Diana; Vavra, Martina; Wagner, Dirk; Kern, Winfried V.; Amaral, Leonard. "O Papel das bombas de efluxo na resistência aos antibióticos em micobactérias do complexo M. avium.". Trabalho apresentado em IX Congresso Nacional de Doenças Infecciosas e Microbiologia Clínica, Sida e Parasitologia, 2008.
  135. Sofia Santos Costa; Isabel Couto; Miguel Viveiros; MARTINS Marta; Clara Leandro; Leonard Amaral; Costa, Sofia Santos; et al. "Characterization of reduced susceptibility to biocides, dyes, and quinolones in a Staphylococcus aureus strain exposed to ethidium bromide". Trabalho apresentado em National Congress of Microbiology (Micro07). Lisbon, Portugal, 2007.
  136. Couto, Isabel; Machado, Diana; Viveiros, Miguel; Rodrigues, Liliana; Amaral, Leonard. "Molecular identification of non-tuberculosis mycobacteria from Lisbon hospitals: a two-year study.". Trabalho apresentado em MICRO¿07 BIOTEC¿07-XXXIII JPG, 2007.
  137. Couto, Isabel; Viveiros, Miguel; Machado, Diana; Rodrigues, Liliana; Martins, Marta; Amaral, Leonard. "Identification of non-tuberculosis mycobacteria in clinical samples using molecular methods: a two-year study.". Trabalho apresentado em 47th International Congress on Antimicrobial Agents and Chemotherapy, 2007.
  138. T Faria; R Carvalho; C Araújo; Nina, Jaime; T Pacheco; Viveiros, Miguel; F Borges; et al. "Admited cases of tuberculosis (TB) and resistant TB in a central hospital (Egas Moniz Hospital): evaluation of a three years period - January 1996 to December 1998". Trabalho apresentado em 7th European Conference on Clinical Aspects and Treatment of HIV-Infection, 1999.
  139. W.F. Canas Ferreira; A. Santos Pinto; A.P. Silva; E. Prieto; R. Albuquerque; C. Costa; F. Dias; et al. "Natural history of HIV-2 infection in an urban population from Guinea-Bissau: clinical and immunologic outcome, 1986-1992". 1993.
  140. João Piedade; Miguel Viveiros; C. Costa; A. Santos Pinto; E. Prieto; R. Albuquerque; L. Brum; et al. "Seroprevalence and risk factors associated with HIV infection in Guinea-Bissau". 1992.
Resumo em conferência
  1. Ferreira, Carolina; Leal, Marta; Andrade, Mariana; Abrantes, Patrícia; Viveiros, Miguel; Costa, S. Sofia; Couto, Isabel. "Occurrence of norA and other multidrug efflux pump determinants across the Staphylococcus genus.". Trabalho apresentado em Accepted for poster presentation at 19th International Symposium on Staphylococci and Staphylococcal Infections (ISSSI), 18-21 August, Perth., Perth, 2024.
  2. Neves, Joana; Andrade, Mariana; Bento, Maria; Viveiros, Miguel; Rodrigues, Liliana; Couto, Isabel; Costa, S. Sofia. "New candidate drugs for repurposing as efflux inhibitors and antibiofilm agents against antimicrobial-resistant staphylococcus aureus and staphylococcus epidermidis.". Trabalho apresentado em Accepted for oral presentation at 19th International Symposium on Staphylococci and Staphylococcal Infections (ISSSI), 18-21 August, Perth., Perth, 2024.
  3. Andrade, Mariana; Neves, Joana; Bento, Maria; Marques, Joana; Viveiros, Miguel; Rodrigues, Liliana; Armada, Ana; et al. "Galleria mellonella as a reliable in vivo model to evaluate repurposed drugs for Staphylococcus infection therapeutics.". Trabalho apresentado em Accepted for oral presentation at 19th International Symposium on Staphylococci and Staphylococcal Infections (ISSSI), 18-21 August, Perth., 2024.
  4. Ana Tavares; Miriam Jauset-Rubio; Mayreli Ortiz; Marcelo U. Ferreira; Diana Machado; Miguel Viveiros; Arez, Ana Paula; Ciara K. O'Sullivan. "Utilização de biosensores na deteção rápida de SNPs associados à resistência aos antimaláricos com base na estratégia de amplificação isotérmica.". 2023.
  5. Diana Machado; Sarah Gothe; Marta Martins; Teresa Pacheco; Judite Batista; Cristina Toscano; Miguel Viveiros. "Colistin heteroresistance in carbapenemase-producing Acinetobacter baumannii". 2020.
  6. Diana Machado; Marco Pieroni; Miguel Viveiros. "Development of lipophilic efflux inhibitors as adjuvants of Mycobacterium tuberculosis chemotherapy". 2020.
  7. Thomas Schön; Erja Chryssanthou; H.Benmansour Florian Maurer; S. Boarbi; Petter Keller; Miguel Viveiros; Diana Machado; et al. "ECOFFs for non-tuberculous mycobacteria: towards a EUCAST reference method and clinical breakpoints for antimicrobial susceptibility testing". 2020.
  8. Diana Machado; Elisa Azzali; Isabel Couto; Gabriele Costantino; Marco Pieroni; Miguel Viveiros. "Targeting Mycobacterium tuberculosis with lipophilic efflux inhibitors exploring their dual activity: dissipation of the proton motive force and efflux inhibition". 2019.
  9. Jéssica Antunes; Diana Machado; Marta Martins; Isabel Couto; Teresa Pacheco; Judite Batista; Cristina Toscano; Miguel Viveiros. "Contribution of ß-lactamases, porins and efflux pumps to carbapenem resistance in Acinetobacter baumannii". 2019.
  10. Diana Machado; João Perdigão; Jorge Ramos; Ana Tavares; Abecasis AB; Sónia Dias; Taane G. Clark; et al. "Exploring the phenotypic and genetic basis of drug-resistant Mycobacterium tuberculosis strains in Lisbon, Portugal". 2019.
  11. Sarah Gothe; Diana Machado; Marta Martins; Teresa Pacheco; Judite Batista; Cristina Toscano; Miguel Viveiros. "Insights on Acinetobacter baumannii heteroresistance to colistin: what is the fate?". 2019.
  12. Miguel Viveiros; Diana Machado; Iolanda Neves; Marta Martins; Isabel Couto; Teresa Pacheco; Judite Batista; Cristina Toscano. "The contribution of membrane transporter proteins to extensively-drug resistant phenotypes in Acinetobacter baumannii". 2019.
  13. Thomas Schön; Miguel Viveiros; Jim Werngren; Daniella Cirrillo; Emanuele Borroni; Maria Wijkander; Diana Machado; et al. "Towards a new reference drug susceptibility testing method for Mycobacterium tuberculosis". 2019.
  14. Liliana Rodrigues; Pedro Cravo; Miguel Viveiros. "In silico repurposing of approved drugs against tuberculosis: targeting membrane transporters and energy metabolism". 2019.
  15. Diana Machado; João Perdigão; Jorge Ramos; Ana Tavares; Abecasis AB; Sónia Dias; Taane Clark; et al. "Epidemiologia molecular da resistência em Mycobacterium tuberculosis multirresistente em Lisboa". 2019.
  16. Denise O'Sullivan; Jody Phelan; Diana Machado; Miguel Viveiros; Taane G. Clark; Justin O'Grady; Jim F. Huggett. "Evaluation of the performance of MinION sequencing to identify multi- and extensively drug resistant tuberculosis". 2018.
  17. João Perdigão; Carla Silva; Jaciara Diniz; Catarina Pereira; Diana Machado; Jorge Ramos; Fernanda Silva; et al. "Genetic diversity and mapping of M. tuberculosis strains in Portuguese Speaking Countries". 2017.
  18. Jéssica Antunes; Diana Machado; Isabel Couto; Teresa Pacheco; Judite Batista; Cristina Toscano; Miguel Viveiros. "The contribution of efflux pumps and porins in Acinetobacter baumannii resistance to carbapenems". 2017.
  19. João Perdigão; Carla Silva; Jaciara Diniz; Catarina Pereira; Diana Machado; Jorge Ramos; Fernanda Silva; et al. "Tracking Mycobacterium tuberculosis across the seas: CPLP-TB and genetic diversity in the Lusophone space". 2017.
  20. A Armada; Bruno Costa Gomes; Jose Rueff; Miguel Viveiros; Antonio Sebastião Rodrigues. "Evaluation of the modulating effect of miR-203 and miR-200c on drug extrusion by ABCB1". 2017.
  21. Santos-Gomes, G; M. Rafael-Fernandes; A Armada; P. Ruas; J.H. Lago; F. Passero; Miguel Viveiros. "Eficácia da terapia combinada como estratégia alternativa ao tratamento convencional das leishmanioses.". 2017.
  22. Diana Machado; Faiza Mougari; Emmanuelle Cambau; Miguel Viveiros. "Genome downsizing and drug resistance in Mycobacterium leprae: are there places for drug efflux pumps?". 2016.
  23. A Armada; Bruno Costa Gomes; Jose Rueff; Antonio Sebastião Rodrigues; Miguel Viveiros. "MicroRNAs 203 e 200c regulam a expressão das bombas ABCB1 na resistência à doxorubicina". 2016.
  24. T. Mendes; A. Pinto-Almeida; Pedro Ferreira; A Armada; Miguel Viveiros; Silvana Belo; A. Afonso. "Avaliação do envolvimento das bombas de efluxo na fármaco-resistência ao Praziquantel em Schistosoma mansoni.". 2014.
  25. Cabral, V; Luo, X; Junqueira, E; Costa, S; Mulhovo, S; Duarte, A; Couto, I; Viveiros, M; Ferreira, MJU. "Zanthoxylum capense constituents and derivatives: Effects on the activity of antibiotics against Staphylococcus aureus strains". 2014.
    10.1055/s-0034-1395089
  26. Diana Machado; David Pires; João Perdigão; Jorge Ramos; Isabel Couto; Isabel Portugal; Elsa Anes; et al. "Efflux inhibitors against drug resistant Mycobacterium tuberculosis: antimicrobial agents and enhancers of macrophage killing activity". Trabalho apresentado em MicroBiotec¿13, 2014.
  27. Martins, C; Armada, A; Viveiros, M; Rueff, J; Rodrigues, AS. "Allylbenzenes as potential chemosensitizers and P-glycoprotein inhibitors". 2013.
  28. Diana Machado; Isabel Couto; Jorge Ramos; Miguel Viveiros. "Inibidores de efluxo como adjuvantes no tratamento da tuberculose resistente aos antibacilares". 2013.
  29. Diana Machado; Miguel Viveiros; Samuel Francisco; Jorge Ramos; Carlos Serra; Teresa Pacheco; Teresa Marques; et al. "Detecção directa de MDRTB em Portugal: métodos e aplicações comerciais. A experiência do IHMT". 2013.
  30. Pedro Pedrosa; Bruno Veigas; Diana Machado; João Perdigão; Isabel Portugal; Isabel Couto; Miguel Viveiros; P. V. Baptista. "Detecção de MDRTB por gold-nanoprobes – uma nova abordagem tecnológica desenvolvida em Portugal". 2013.
  31. Miguel Viveiros; Liliana Rodrigues; Diana Machado; Marta Martins; Isabel Couto; Leonard Amaral. "Significance of efflux in multidrug resistance in Mycobacterium tuberculosis". 2013.
  32. Paulo Rabna; Jorge Ramos; Gema Ponce; Fina Bamba; Diana Machado; A Armada; Lilica Sanca; et al. "Detecção directa da TB-MR através do teste Xpert MTB/RIF na Guiné-Bissau". 2013.
  33. Diana Machado; Isabel Couto; Jorge Ramos; Miguel Viveiros. "Anti-tuberculosis activity of efflux inhibitors against drug resistant Mycobacterium tuberculosis". 2013.
  34. Diana Machado; João Perdigão; Jorge Ramos; Isabel Couto; Isabel Portugal; Claudia Ritter; Erik C. Boettger; Miguel Viveiros. "High level resistance to isoniazid and ethionamide among multidrug resistant Mycobacterium tuberculosis strains from Lisbon, Portugal, is associated with double mutations in inhA gene". 2012.
  35. Diana Machado; João Perdigão; Jorge Ramos; Isabel Couto; Isabel Portugal; Claudia Ritter; Eric C. Boettger; Miguel Viveiros. "Resistência de alto nível à isoniazida e etionamida em estirpes de Mycobacterium tuberculosis multirresistentes está associada a mutações duplas no gene inhA". 2012.
  36. Miguel Viveiros; Diana Machado; Isabel Couto; João Perdigão; Isabel Portugal; Emmanuelle Cambau; Erik C. Boettger. "O teste de susceptibilidade semi-quantitativo de 1a e 2a linha para Mycobacterium tuberculosis usando o sistema BD EpiCenterTM TB-eXiST: um importante contributo para a Luta Contra a Tuberculose Resistente aos antibióticos". 2012.
  37. Martins, A; Vasas, A; Schelz, Z; Martins, M; Viveiros, M; Molnar, J; Hohmann, J; Amoral, L. "Purification and identification of active compounds of Carpobrotus edulis against the reversal of resistance of human mdr1 gene transfected mouse lymphoma cells". 2008.
  38. Amaral, L; Spengler, G; Viveiros, M; Rodrigues, L; Martins, A; Couto, I; Martins, M; et al. "ASSESSMENT AND COMPARISON OF EFFLUX PUMPS OF CANCER CELLS AND MDR BACTERIA UNDER PHYSIOLOGICAL CONDITIONS BY A REAL-TIME SEMI-AUTOMATED SYSTEM". 2008.
  39. Spengler, G; Viveiros, M; Martins, A; Rodrigues, L; Martins, M; Molnar, J; Couto, I; Amaral, L. "DEMONSTRATION OF THE ACTIVITY OF P-GLYCOPROTEIN BY A FULLY AUTOMATED ETHIDIUM BROMIDE METHOD". 2008.
  40. Amaral, L; Ordway, D; Viveiros, M; Martins, M; Leandro, C. "Thioridazine: evidence supporting its use as alternative therapy for MDR-TB". 2004.
  41. Amaral, L; Martins, M; Viveiros, M; Leandro, C; Ordway, D; Molnar, J. "VERAPAMIL AND RESERPIN PROMOTE THE KILLING OF INTRACELLULAR BACTERIA". 2004.
  42. João Piedade; Miguel Viveiros; C. Costa; A. Santos Pinto; E. Prieto; R. Albuquerque; A. Paulo Silva; et al. "HIV-2 seroprevalence in Guinea-Bissau". 1993.
Revisão de livro
  1. Guerreiro, Cátia Sá; Hartz, Zulmira; Sambo, Luís; Conceição, Cláudia; Dussault, Gilles; Russo, Giuliano; Viveiros, Miguel; et al. "Scientific Research Policy for Health in Portugal: II - Facts and Suggestions". https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/8012.
  2. Sá Guerreiro, Cátia; Hartz, Zulmira; Sambo, Luís; Conceição, Cláudia; Dussault, Gilles; Russo, Giuliano; Viveiros, Miguel; et al. "Scientific Research Policy for Health in Portugal: I - European and National Environment". https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/8011.
  3. Rodrigues, Liliana; Cravo, Pedro; Viveiros, Miguel. "Efflux pump inhibitors as a promising adjunct therapy against drug resistant tuberculosis". http://hdl.handle.net/10362/105619.
    https://doi.org/10.1080/14787210.2020.1760845
  4. Simões, Alexandra S.; Couto, Isabel; Toscano,  Cristina; Gonçalves, Elsa; Póvoa, Pedro; Viveiros, Miguel; Lapão, Luís V.. "Prevention and control of antimicrobial resistant healthcare-associated infections". http://hdl.handle.net/10362/116814.
    https://doi.org/10.3389/fmicb.2016.00855
Tese / Dissertação
  1. MAIA, Inês Lopes Pinheiro de Oliveira. "Estudo de competição entre substratos de bombas de efluxo em isolados clínicos de Escherichia coli por fluorimetria em tempo real usando Vermelho do Nilo". Mestrado, 2022. http://hdl.handle.net/10362/146124.
  2. VIEGAS, Sarah Gothe Esteves. "Insights on the mechanisms underlying the development of heteroresistance to colistin in Acinetobacter baumannii". Mestrado, 2022. http://hdl.handle.net/10362/159181.
  3. Ribeiro, José Francisco Valente. "Uma abordagem bioinformática para o estudo da contribuição das bombas de efluxo “Small Multidrug Resistance” na resistência aos antibióticos em Acinetobacter baumannii através da análise de genoma completo". Mestrado, 2020. http://hdl.handle.net/10362/93123.
  4. Serra, Débora Carvalho. "Detection and inhibition of ß-lactamase activity in clinical isolates of Escherichia coli combining ß-lactamase and efflux inhibitors using an MTT-based method: phenotypic and genotypic validation". Mestrado, 2020. http://hdl.handle.net/10362/97300.
  5. ARMADA, Ana Maria Buttle de Mendonça Mourão Possidónio de. "ABC efflux pumps in eukaryotic cells from function to regulation". Doutoramento, 2019. http://hdl.handle.net/10362/66659.
  6. FERREIRA, Mónica Eduarda Franco. "Diagnóstico e tratamento da infeção malárica: desenvolvimento de uma nova plataforma de diagnóstico e de um novo composto antimalárico". Mestrado, 2019. http://hdl.handle.net/10362/66269.
  7. TAVARES, Ana Maria Pinho. "HIV, tuberculosis and co-infection among migrant populations living in Portugal". Doutoramento, 2019. http://hdl.handle.net/10362/105852.
  8. RODRIGUES, Fátima Alexandra Tavares. "Caracterização dos mecanismos de resistência à colistina em isolados clínicos de Acinetobacter baumannii resistentes aos carbapenemos". Mestrado, 2019. http://hdl.handle.net/10362/116358.
  9. COSTA, Ana Raquel Esteves. "Contribuição do efluxo para a emergência da resistência em bactérias persistentes". Mestrado, 2018. http://hdl.handle.net/10362/53496.
  10. FRANCISCO, Moisés. "Caracterização microbiológica e molecular das estirpes de Salmonella spp. isoladas em amostras clínicas, águas residuais e alimentos na região de Luanda e dos seus perfis de resistência aos antimicrobianos - o seu impacto na saúde pública.". Doutoramento, 2018. http://hdl.handle.net/10362/59484.
  11. THERON, Maria João de Resende. "Determinação da actividade de efluxo de Hoechst 33258 em Escherichia coli". Mestrado, 2018. http://hdl.handle.net/10362/66373.
  12. Antunes, Jéssica. "Estudo da contribuição de bombas de efluxo,porinas e ß-lactamases na resistência aos carbapenemos em isolados clínicos de Acinetobacter baumannii". Mestrado, 2018. http://hdl.handle.net/10362/114950.
  13. ANTUNES, Samuel Filipe Jesus. "Aplicação de um método fluorométrico em placa de 96 poços para a detecção de actividade de efluxo em bactérias". Mestrado, 2017. http://hdl.handle.net/10362/53802.
  14. GABRIEL, Marta Isabel Martins. "Resposta imunitária inflamatória de macrófagos na presença de inibidores de efluxo". Mestrado, 2016. http://hdl.handle.net/10362/19084.
  15. SIMÕES, Ana Sofia Mourão. "Contribuição do efluxo para a aquisição de resistência aos antibióticos em isolados clínicos de Acinetobacter baumannii". Mestrado, 2016. http://hdl.handle.net/10362/19196.
  16. EUSÉBIO, Ana Sofia Sancho. "Determinantes genéticos de virulência e de resistência aos antibióticos em isolados uropatogénicos de Escherichia coli provenientes da comunidade e do hospital.". Mestrado, 2015. http://hdl.handle.net/10362/19064.
  17. MACHADO, DIANA. "The dynamics of drug resistance in Mycobacterium tuberculosis: exploring the biological basis of multi- and extensively drug resistant tuberculosis (MDR/XDRTB) as a route for alternative therapeutic strategies". Doutoramento, 2014. http://hdl.handle.net/10362/20311.
  18. Chocalheiro, Ana Luísa Mateus. "Lab on paper: biossensores colorimétricos de papel para a detecção de membros do complexo Mycobacterium tuberculosis". Mestrado, 2014. http://hdl.handle.net/10362/13836.
  19. COSTA, Pedro Miguel Nisa. "Improved nucleic acid testing strategies to detect and discriminate veterinary relevant Mycobacterium tuberculosis complex members". Doutoramento, 2014. http://hdl.handle.net/10362/19272.
  20. PINTO, Antónia Rosa Trindade. "Resistência mediada por efluxo em Escherichia coli: novas estratégias terapêuticas utilizando antibióticos e inibidores do efluxo". Mestrado, 2012. http://hdl.handle.net/10362/14014.
  21. Cabral, Vanessa Roque. "Pesquisa de compostos com actividade inibidora de bombas de efluxo bacterianas". Mestrado, 2012. http://hdl.handle.net/10451/11231.
  22. RAMOS, Jorge Alexandre Santos. "Transporte do brometo de etídio através da parede celular de Mycrobacterium smegmatis: desenvolvimento e aplicação de metodologias de quantificação do transporte e correlação com a resistência aos antibióticos". Mestrado, 2010. http://hdl.handle.net/10362/10272.
  23. RODRIGUES, Liliana Isabel Dias; Rodrigues, Liliana. "The role of the efflux mechanisms in multidrug resistance in Mycobacterium tuberculosis". Doutoramento, 2010. http://hdl.handle.net/10362/4813.
  24. MACHADO, Diana Oliveira. "Dinâmica fisiológica e mutacional da multirresistência em Mycobacterium tuberculosis". Mestrado, 2009. http://hdl.handle.net/10362/19211.
  25. CHAREPE, Nadia Borges. "Impacto da sobre-expressão de bombas de efluxo de estirpes E. coli MDR clínicas na resistência aos compostos antimicrobianos". Mestrado, 2008. http://hdl.handle.net/10362/19222.
  26. MARTINS, Marta Sofia Lopes. "The role played efflux systems on the resistance to antibiotics". Doutoramento, 2008. http://hdl.handle.net/10362/61898.
  27. MARTINS, Marta Sofia Lopes. "The antimycobacterial activity of thioridazine derivatives against drug resistant Mycobacterium tuberculosis: in vitro, ex vivo and in vivo studies". Doutoramento, 2008. http://hdl.handle.net/10362/61780.

Outros

Outra produção
  1. Antimicrobial resistance, society and environment. Funding Information: GHTM ( UID/Multi/04413/2019 ) is Funded by the Portuguese Science Foundation (FCT).. 2023. Ferrinho, Paulo; Viveiros, Miguel; Fronteira, Inês. http://hdl.handle.net/10362/154662.
    https://doi.org/10.1016/j.onehlt.2023.100512
  2. Editorial. Funding sponsor: Ministero della Salute, Italia Funding Information: The editors thank all the authors for the amazing work grouped in this Research Topic and all the scientists that achieved the reviewing of these manuscripts. The study was partially funded by the Italian Ministry of health, Ricerca corrente, linea 4.. Tuberculosis (TB), is one of the top 10 causes of death worldwide (WHO). Accor. 2021. Opota, Onya; Mazza-Stalder, Jesica; Viveiros, Miguel; Cambau, Emmanuelle; Santin, Miguel; Goletti, Delia. http://hdl.handle.net/10362/128859.
    https://doi.org/10.3389/fpubh.2021.666187
  3. Author Correction. An amendment to this paper has been published and can be accessed via a link at the top of the paper.. 2020. Verza, Mirela; Scheffer, Mara Cristina; Salvato, Richard Steiner; Schorner, Marcos André; Barazzetti, Fernando Hartmann; de Melo Machado, Hanalydia; Medeiros, Taiane Freitas; et al. http://hdl.handle.net/10362/116503.
    https://doi.org/10.1038/s41598-020-76386-7
  4. CPLP-TB: a new tuberculosis transnational surveillance tool for the lusophone community. Tuberculosis (TB) remains a major health problem within the Community of Portuguese Language Speaking Countries (CPLP). Despite the marked variation in TB incidence across its member-states and continued human migratory flux between countries, a considerable gap in the knowledge on the Mycobacterium tuberculosis population structure and strain circulation between the countries still exists. To add. 2019. Perdigão, João; Silva, Carla; Diniz, Jaciara; Pereira, Catarina; Machado, Diana; Ramos, Jorge; Silva, Hugo; et al. http://anaisihmt.com/index.php/ihmt/article/view/278.
    https://doi.org/10.25761/anaisihmt.278
  5. Perceptions of primary care providers on TB care for migrants. a mixed methods study in Portugal. 2019. AM Tavares; AC Garcia; A Gama; AB Abecasis; Miguel Viveiros; Sónia Dias. https://novaresearch.unl.pt/en/publications/0983da5a-3fbe-4caa-9b99-0fcabb18cfea.
  6. Brief history of mycobacteriology at IHMT/UNL. This article reviews the studies on tuberculosis and other mycobacterial diseases at the Institute of Hygiene and Tropical Medicine, over more than one hundred years of history of this institute. If in the first decades these studies were focused on the public care and support to the local health programs to control tuberculosis in all the countries and provinces where the institute was operating. 2018. Viveiros, Miguel; Couto, Isabel. http://anaisihmt.com/index.php/ihmt/article/view/168.
  7. Little history of RIDES-Tuberculosis in the Framework of the Strategic Plan 2009-2012 for cooperation in health of the Community of Portuguese Speaking Countries. Tuberculosis remains a major public health problem world-wide. In 2016, the WHO launched an appeal to governments, communities, civil society and the private sector to be "United to End Tuberculosis", promoting the dialogue and collaboration that unites people and communities to implement new ways to end the epidemic of tuberculosis (TB) and in particular of drug-resistant TB that continues to inc. 2018. Viveiros, Miguel; Simões, Maria João. http://anaisihmt.com/index.php/ihmt/article/view/104.
    https://doi.org/10.25761/anaisihmt.104
  8. Challenging the Drug-Likeness Dogma for New Drug Discovery in Tuberculosis. 2018. Machado, D; Girardini, M; Viveiros, M; Pieroni, M; Machado, Diana; Girardini, Miriam; Viveiros, Miguel; Pieroni, Marco. http://hdl.handle.net/10362/116865.
    10.3389/fmicb.2018.01367
  9. Tuberculosis across the seas: CPLP-TB - a joint effort in cataloguing mycobacterium tuberculosis genetic diversity in the lusophone space. The Community of Portuguese Language Speaking Countries (CPLP) comprises nine countries across four continents, accounting for 7.2% of the world’s land area, and where tuberculosis (TB) is still a cause of public health concern. A marked variation in TB incidence (23 to 551 cases per 100 000 habitants) can be observed across the different member-states and, despite of this, a considerable gap in t. 2017. Perdigão, João; Silva, Carla; Diniz, Jaciara; Pereira, Catarina; Machado, Diana; Ramos, Jorge; da Silva, Fernanda; et al. http://hdl.handle.net/10400.18/4737.
  10. Mutational and physiological dynamic of drug resistance in Mycobacterium tuberculosis, OP-8.. 2010. Isabel Couto; Miguel Viveiros; Leonard Amaral. https://research.unl.pt/en/publications/mutational-and-physiological-dynamic-of-drug-resistance-in-mycobacterium-tuberculosis-op8(eb43570e-c273-4345-bc26-136e07324a6b).html.
  11. Evaluation of the BD MGIT™ TBc identification test for the rapid detection of M. tuberculosis complex from cultures. 2010. Leonard Amaral; Isabel Couto; Miguel Viveiros. https://unl.elsevierpure.com/en/publications/852fbf2f-fa8c-4bff-8437-fe74e987366c.
  12. Biological activity of hydantoin derivatives on efflux pump systems of bacteria and cancer cells.. 2010. Miguel Viveiros; Leonard Amaral. https://unl.elsevierpure.com/en/publications/db229c15-d116-4be6-87cb-ad33967082fc.
  13. Contribution of efflux activity to isoniazid resistance in Mycobacterium tuberculosis complex. (1). 2010. Miguel Viveiros; Leonard Amaral; Isabel Couto. https://unl.elsevierpure.com/en/publications/65337d27-8492-4b93-8155-243c494e5ef6.
  14. Contribution of the Mmr efflux pump to antimicrobial resistance in M. tuberculosis: construction of a mmr knockout mutant by allelic exchange.. 2010. Miguel Viveiros. https://unl.elsevierpure.com/en/publications/4b97f2f5-c873-4d86-a486-218440d194a6.
  15. Aedes (Stegomyia) aegypti (Diptera: Culicidae) in the Madeira Archipelago: bioecology.. 2010. Miguel Viveiros; António Grácio. https://unl.elsevierpure.com/en/publications/3033f072-c9f4-48f5-a3de-2b7b9372560d.
  16. Energetics, pH and intrinsic efflux pump systems of Gram-negative pathogens.. 2010. Miguel Viveiros; Leonard Amaral; Isabel Couto. https://unl.elsevierpure.com/en/publications/5fb0d562-3b6e-468b-982c-7e974f991c86.
  17. Mutational adaptation in Mycobacterium tuberculosis: the emergence of multidrug resistance.. 2009. Miguel Viveiros; Leonard Amaral; Isabel Couto. https://research.unl.pt/en/publications/mutational-adaptation-in-mycobacterium-tuberculosis-the-emergence-of-multidrug-resistance(b4e15613-3b79-473a-acb6-22c39f38340e).html.
  18. Early detection of MDRTB by molecular tools in the control of drug resistant tuberculosis in Portugal: a case of success.. 2009. Leonard Amaral; Isabel Couto; Miguel Viveiros. https://research.unl.pt/en/publications/early-detection-of-mdrtb-by-molecular-tools-in-the-control-of-drug-resistant-tuberculosis-in-portugal-a-case-of-success(e1f38d60-5dd6-4572-ae45-7940ef9fd8b0).html.
  19. Contribution of efflux pump activity of macrolide resistance in M. avium complex.. 2009. Leonard Amaral; Miguel Viveiros; Isabel Couto. https://research.unl.pt/en/publications/contribution-of-efflux-pump-activity-of-macrolide-resistance-in-m-avium-complex(a5a170e9-04ec-490b-b19c-6c6ea5b22cac).html.
  20. The human macrophage as a model to select compounds active against MDR/XDR-TB.. 2009. Miguel Viveiros; Leonard Amaral; Isabel Couto. https://unl.elsevierpure.com/en/publications/f375cc59-f45d-4a80-8e68-85a8f71ec4d5.
  21. The role played by efflux pumps in macrolide resistance in Mycobacterium avium complex.. 2009. Leonard Amaral; Isabel Couto; Miguel Viveiros. https://unl.elsevierpure.com/en/publications/217ce718-ee58-4a4e-b04e-3d76ac470e9d.
  22. New Methods for the Identification of Efflux Mediated MDR Bacteria, Genetic Assessment of Regulators and Efflux Pump Constituents, Characterization of Efflux Systems and Screening for Inhibitors of Efflux Pumps. 2008. Viveiros, M; Martins, M; Couto, I; Rodrigues, L; Spengler, G; Martins, A; Kristiansen, JE; Molnar, J; Amaral, L.
    10.2174/138945008785747734
  23. Thioridazine. evidence supporting its use as alternative therapy for MDR-TB. 2004. L Amaral; Diane Ordway; Miguel Viveiros; M Martins; C Leandro; Amaral, Leonard; Viveiros, Miguel; et al. https://novaresearch.unl.pt/en/publications/43b8add9-759a-49bb-804b-03160b0d6f52.
    https://doi.org/10.3390/antibiotics6010003
  24. Health care workers who are to progress to active TB disease present a panel of T cell immune markers predicting such progression. 2004. C. Leandro; Diane Ordway; Miguel Viveiros; Maria Jorge Perinhas Arroz; L. Pinto; F. A. Ventura; Hazel M. Dockrell; Leonard Amaral. https://novaresearch.unl.pt/en/publications/21979caf-c025-471c-81f0-a7dfca828cd6.
  25. Plant extract kills intracellular MDR pathogens reverses MDR of cancer and steps up T cell activity. 2004. Miguel Viveiros; Diane Ordway; Judit Hohmann; Clara Leandro; Joseph Molnar; Leonard Amaral; Viveiros, M; et al. https://novaresearch.unl.pt/en/publications/f30b2adb-5f53-45ae-8f55-3379899dc8f5.
  26. International Journal of Antimicrobial Agents. Foreword. 2003. Leonard Amaral; Miguel Viveiros; Peter Henderson. https://research.unl.pt/en/publications/international-journal-of-antimicrobial-agents(97c60da8-d5c6-4202-9d3f-af694e7345c3).html.
    10.1016/s0924-8579(03)00223-1
Atividades

Orientação

Título / Tema
Papel desempenhado
Curso (Tipo)
Instituição / Organização
2020 - 2020 Uma abordagem bioinformática para o estudo da contribuição das bombas de efluxo “Small Multidrug Resistance” na resistência aos antibióticos em Acinetobacter baumannii através da análise de genoma completo
Coorientador
Microbiologia Médica (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2018 - 2018 Contribuição do efluxo para a emergência da resistência em bactérias persistentes.
Coorientador
Ciências Biomédicas (Mestrado)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2018 - 2018 Aplicação de um método fluorométrico em placa de 96 poços para a deteção de atividade de efluxo em bactérias.
Orientador
Ciências Biomédicas (Mestrado)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2016 - 2016 Resposta imunitária inflamatória de macrófagos na presença de inibidores de efluxo
Orientador
Ciências Biomédicas (Mestrado)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2016 - 2016 Contribuição do efluxo para a aquisição de resistência aos antibióticos em isolados clínicos de Acinetobacter baumannii.
Orientador
Microbiologia Médica (Mestrado)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2015 - 2015 ABC efflux pumps in eukaryotic cells From funtion to regulation
Orientador
Genética Humana e Doenças Infecciosas (Doutoramento)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2014 - 2014 Caracterização microbiológica e molecular das estirpes de Salmonella spp. isoladas em amostras de fezes, águas residuais e em ovos de produção aviárias na região de Luanda e dos seus perfis de resistência aos antimicrobianos - o seu impacto na saúde pública
Orientador
Ciências Biomédicas (Doutoramento)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2013 - 2013 Contribuição dos sistemas de efluxo na resistência à claritromicina no complexo Mycobacterium avium
Orientador
Ciências Biomédicas (Mestrado)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2010 - 2010 The dynamics of drug resistance in Mycobacterium tuberculosis: exploring the biological basis of multi - and multi extensively drug resistant tuberculosis (MDR/XDRTB) as a route for alternative therapeutic strategies
Orientador
Ciências Biomédicas (Doutoramento)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2005 - 2005 The Role of the Efflux Mechanisms in Multidrug Resistance in Mycobacterium Tuberculosis
Orientador
Ciências Biomédicas (Doutoramento)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
Distinções

Prémio

2020 2020 I PFIZER AWARD - Best Poster Communication at the III International Conference NOVAhealth Chronic Disease and Infection: Infection, Cancer and Global Health
2017 2017 | Gilead GÉNESE, referência PGG/012/2017 ( Programa Gilead GÉNESE) Distinção
2017 2017 I Seal of Excellence Europen Union - European Commission, Horizon 2020, EU Framework Programme for Research and Innovation
2020 Agency, Reino Unido

European Union, Bélgica
2017 2017 I Merit Award for the Best Panel Communication on the Section “Health Microbiology and Biotechnology”. National Congress of Microbiology and Biotechnology - Congresso Nacional de Microbiologia e Biotecnologia de 2017
Sociedade Portuguesa de Microbiologia, Portugal
2012 2012 | Santander/Totta – Universidade Nova de Lisboa - Merit Award (Santander/Totta Merit Award )
2009 2009 I Merit Award for Best Panel Communication National Congress of Microbiology and Biotechnology - Congresso Nacional de Microbiologia e Biotecnologia de 2009
Sociedade Portuguesa de Microbiologia, Portugal
2003 2003 I Glaxo-Smithkline Fundation - Merit Award for Research in Infectious Diseases (2º Place) – Portuguese Society of Infectious Diseases
GlaxoSmithKline, Estados Unidos

Título

2014 2014-10-01 a 2017-10-01 | Professor Visitante Especial / Special Visiting Professor (Programa Academico de Tuberculose na Faculdade de Medicina da UFRJ ) Posição convidada
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, Brasil

Universidade Federal do Estado do Rio de Janeiro, Brasil