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Miguel Viveiros Bettencourt. Completed the title of Aggregate in Biomedical Sciences in 2012/04/19 by Universidade Nova de Lisboa/Institute of Hygiene and Tropical Medicine, PhD in Biology in 2001 by Universidade de Lisboa, Master in Biotechnology (Biochemical Engineering) in 1993/10/01 by University of Lisbon Instituto Superior Técnico and Licenciatura em Biologia in 1991/10/01 by University of Lisbon Faculty of Sciences. Full Professor at Universidade Nova de Lisboa/Institute of Hygiene and Tropical Medicine. Coordinator of the FCT Research Center Global Health and Tropical Medicine ( https://ghtm.ihmt.unl.pt/). Published 237 articles in specialized scientific journals. Has 10 book chapter (s) and 3 book (s). Supervised 5 postdocs, (and / or co-supervised) 9 PhD students and 30 Master's students. Dedicated to the study and development of new diagnostic tools and alternative therapies for the treatment of drug-resistant infections, such as multidrug-resistant tuberculosis and methicillin-vancomycin-resistant staphylococcal infections, using new technologies and new therapies incorporating non-antibiotic adjuvants for chemotherapy. Studied, over the past 25 years, the contribution of efflux pumps and membrane transporters to multi-resistant bacterial phenotypes and how we can prevent, reverse or reduce the level of resistance and recover the effectiveness of antibiotics to which the bacteria has become resistant. With an international team of collaborators, he documented mutations in drug targets and the corresponding associated minimum inhibitory concentrations for most anti-TB drug targets in M. tuberculosis and also the effectiveness of several new inhibitors for many of the MDR bacteria, in particular M / XDRTB. Specialist in laboratory diagnosis and characterization of resistance determinants by phenotypic and genotypic assays, using new technical approaches, such as the complete genome sequencing, nanotechnology and phenotypic assays in real time. Many of our studies have demonstrated the public health implications of antibiotic multidrug resistance and have contributed to the improvement of the currently recommended first and second line antiTB treatments. Founding member and treasurer, currently a member of the Study Group on Mycobacterial Infections (ESGMYC) of the European Society for Clinical Microbiology and Infectious Diseases (ESCMID) (https://www.escmid.org/index.php?id = 897). Vice President (2017) and President (2019) of the Gordon Research Conference - Multi-Drug Efflux Systems - 2017-2019 - https://www.grc.org/multi-drug-efflux-systems-conference/2019/). Scientific Coordinator and General Director of “Ciência LP - International Center for Advanced Training in Fundamental Sciences for Scientists from Portuguese Speaking Countries” (UNESCO Category 2 Center) and Vice President of the Portuguese Society of Microbiology (https: // spmicrobiologia. wordpress.com/orgaos-sociais/). Member of the evaluation panel of the Foundation for Science and Technology of Portugal and expert evaluator of MRC South Africa and UK (Tuberculosis area), Wellcome Trust Awards, Research Foundation - Flanders (FWO), Belgium, Haut Conseil de l 'Evaluation de la Recherche et de l'Enseignement Supérieur (HCERES) and National Agency for Scientific Evaluation (ANEP), Spain. Author / co-author of more than 200 scientific articles in national and international journals, books and book chapters on mycobacteriology, bacteriology, antibiotic resistance, microbial genetics, molecular epidemiology and immunology.
Identificação

Identificação pessoal

Nome completo
Miguel Viveiros Bettencourt

Nomes de citação

  • Viveiros, Miguel

Identificadores de autor

Ciência ID
DF17-B4BF-8756
ORCID iD
0000-0001-9676-6251
Google Scholar ID
o39byr4AAAAJ
Researcher Id
A-7326-2008
Scopus Author Id
7003949212

Websites

  • http://www.ihmt.unl.pt/?lang=pt&page=ihmt&subpage=unidades-de-ensino-e-investigacao&m2=54&staff=14 (Profissional)
  • https://novaresearch.unl.pt/en/persons/miguel-viveiros-bettencourt (Académico)
  • https://www.researchgate.net/profile/Miguel-Viveiros (Académico)

Domínios de atuação

  • Ciências Médicas e da Saúde

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Francês Utilizador independente (B1) Utilizador proficiente (C1) Utilizador independente (B1) Utilizador independente (B1)
Espanhol; Castelhano Utilizador independente (B1) Utilizador proficiente (C1) Utilizador independente (B1) Utilizador independente (B1)
Formação
Grau Classificação
2012/04/19
Concluído
Ciências Biomédicas (Título de Agregado)
Especialização em Ciências Biomédicas
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
"“As novas tecnologias de biologia molecular no diagnóstico precoce da tuberculose resistente: a sua integração e monitorização no contexto dos programas de controlo da tuberculose”. " (TESE/DISSERTAÇÃO)
Aprovado com Louvor e Distinção
2001
Concluído
Biologia (Doutoramento)
Especialização em Genética Microbiana
Universidade de Lisboa, Portugal
"Molecular Genetics of Carotenogenesis in Mycobacterium : Cloning and Study of the Mycobacterium Carotenogenic Operon and Application in the Development of a New Efficient Gene Expression System for the Isolation of Genes Associated in Mycobacterium Tuberc" (TESE/DISSERTAÇÃO)
Aprovado com Louvor e Distinção
1993/10/01
Concluído
Biotecnologia (Engenharia Bioquímica) (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
18/20
1991/10/01
Concluído
Biologia (Licenciatura)
Especialização em Microbiologia
Universidade de Lisboa Faculdade de Ciências, Portugal
16/20
Percurso profissional

Docência no Ensino Superior

2013/07/01 - Atual Professor Catedrático (Docente Universitário)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal

Cargos e Funções

2020/03/15 - Atual Coordenação ou direção de centro de investigação, departamento ou equivalente
Universidade Nova de Lisboa Saúde Global e Medicina Tropical, Portugal
2010 - Atual Conselho científico/técnico-científico ou orgão correspondente
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2015 - 2020 Conselho geral ou orgão correspondente
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2010 - 2020 Conselho pedagógico
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
Projetos

Projeto

Designação Financiadores
2018 - 2021/11/14 Imunoterapias contra sistemas de efluxo para modulação de bactérias multiresistentes
PTDC/BTM-SAL/30550/2017
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Universidade Nova de Lisboa, Portugal
Fundação para a Ciência e a Tecnologia
2018 - 2021/09/30 Identificação de novos tratamentos antimaláricos através de uma abordagem de "reposicionamento de fármacos" centrada no alvo
PTDC/SAU-PAR/28459/2017
Investigador
Universidade Nova de Lisboa, Portugal
Fundação para a Ciência e a Tecnologia
2018 - 2021/09/30 O uso de biocidas na prevenção da resistência aos antimicrobianos na comunidade.
PTDC/CAL-EST/30713/2017
Investigador
Universidade Nova de Lisboa, Portugal

Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
Fundação para a Ciência e a Tecnologia
2018 - 2021/09/30 Bombas de efluxo como alvos terapêuticos em Mycobacterium tuberculosis resistente aos antibióticos: uma abordagem para prevenir a resistência mediada por efluxo e potenciar a terapêutica na tuberculose activa e latente
PTDC/BIA-MIC/30692/2017
Investigador responsável
Universidade Nova de Lisboa, Portugal
Fundação para a Ciência e a Tecnologia
2018 - 2021/09/30 Em busca de novos derivados de isoniazida eficazes no combate à tuberculose multi-resistente: uma abordagem integrada de química medicinal
PTDC/MED-QUI/29036/2017
Investigador
Universidade Nova de Lisboa, Portugal
Fundação para a Ciência e a Tecnologia
2018 - 2021/08/31 Líquidos Iónicos Farmaceuticos como uma nova plataforma para o tratamento efectivo da Tuberculose (TB-ILs)
PTDC/QUI-QOR/32406/2017
Investigador
Associação para a Inovação e Desenvolvimento da FCT, Portugal

Universidade Nova de Lisboa, Portugal
Fundação para a Ciência e a Tecnologia
2018 - 2020/03/31 Chemogenomics and in silico repurposing as an innovative approach for rapid drug discovery in tuberculosis
NUMBER — 795924 — iCHEMGENODRUGS_TB
Investigador responsável
Universidade Nova de Lisboa Saúde Global e Medicina Tropical, Portugal

Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
EUROPEAN COMMISSION Research Executive Agency
2018 - 2020/03 Chemogenomics and in silico repurposing as an innovative approach for rapid drug discovery in tuberculosis
NUMBER 795924 iCHEMGENODRUGS_TB
EUROPEAN COMMISSION Research Executive Agency
2013 - 2015/12 OSYRISH - Organizational and Informational System to Improve the Communication Management of Healthcare Associated Infections in Hospitals
Provided by PTCRIS: 132200
132200
PTDC/IVC-COM/5016/2012
Investigador
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
Fundação para a Ciência e a Tecnologia

Fundação para a Ciência e a Tecnologia
2012 - 2015/03 Type-II NADH-menaquinone oxidoreductase (NDH-2) and the respiratory chain of M. tuberculosis: new therapeutic targets to fight tuberculosis.
121859
Provided by PTCRIS: 121859
PTDC/BIA-MIC/121859/2010
Investigador
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal

Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal

Associação para a Inovação e Desenvolvimento da FCT, Portugal
Fundação para a Ciência e a Tecnologia

Fundação para a Ciência e a Tecnologia
2010 - 2013/08/31 Aumento da capacidade de morte (killing activity) de macrófagos humanos infectados por Mycobacterium tuberculosis multi-resistente (MDRTB): uma nova estratégia quimioterapêutica para combater a tuberculose multi-resistente.
PTDC/SAU-FCF/102807/2008
Investigador responsável
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal

Universidade Nova de Lisboa Unidade de Ensino e Investigação de Parasitologia Médica, Portugal
Fundação para a Ciência e a Tecnologia
2010 - 2013/08/31 Descrição do mecanismo de acção de adjuvantes da antibioterapia de bactérias multirresistentes
PTDC/BIA-MIC/105509/2008
Investigador responsável
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal

Universidade de Lisboa Instituto Superior Técnico, Portugal
Fundação para a Ciência e a Tecnologia
2010 - 2013/08 Enhancing the killing of intracellular multi-drug resistant tuberculosis (MDRTB) by human macrophages: a new chemotherapeutic strategy to fight MDRTB.
102807
Provided by PTCRIS: 102807
Investigador responsável
Fundação para a Ciência e a Tecnologia
2010 - 2013/08 Helper compounds against multidrug resistant bacteria: revealing their mechanism of action
105509
Provided by PTCRIS: 105509
Investigador responsável
Fundação para a Ciência e a Tecnologia
2009 - 2012/08/01 Do Design à Síntese de Novos Agentes Anti-Tuberculares
PTDC/QUI/67933/2006
67933
Provided by PTCRIS: 67933
Investigador
Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal

Universidade de Lisboa Centro de Química e Bioquímica, Portugal

Universidade de Lisboa Faculdade de Farmácia, Portugal

Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
Fundação para a Ciência e a Tecnologia

Fundação para a Ciência e a Tecnologia
2008 - 2011/06/30 Dinâmica fisiológica e mutacional da resistência aos antibióticos em Mycobacterium tuberculosis: a emergência da Tuberculose Multi-Resistente.
PTDC/BIA-MIC/71280/2006
Investigador responsável
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal

Universidade Nova de Lisboa Unidade de Ensino e Investigação de Parasitologia Médica, Portugal
Fundação para a Ciência e a Tecnologia
2008 - 2011/06 Mutational and physiological dynamics of drug resistance in Mycobacterium tuberculosis: the emergence of Multi-Drug Resistant Tuberculosis.
71280
Provided by PTCRIS: 71280
Investigador responsável
Fundação para a Ciência e a Tecnologia
2007 - 2009/06 Efflux-pumps in drug resistance of Mycobacterium tuberculosis: Molecular characterisation of the efflux mechanism and use of efflux inhibitors as new anti-tubercular compounds
Provided by PTCRIS: 82329
82329
Provided by PTCRIS: 59370
59370
Investigador responsável
Fundação para a Ciência e a Tecnologia
2005 - 2007/12/31 Bombas de efluxo em Mycobacterium tuberculosis: caracterizacão molecular dos mecanismos de efluxo e uso de inibidores de efluxo como novos compostos anti-bacilares
POCI/SAU-MMO/59370/2004
Investigador responsável
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal

Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal

Universidade de Lisboa Instituto Superior Técnico, Portugal
Fundação para a Ciência e a Tecnologia
1995 - 1997/12/31 GENÉTICA MOLECULAR DA CAROTENOGÉNESE EM MYCOBACTERIUM
PRAXIS XXI/BD/3962/94
Bolseiro de Doutoramento
Universidade de Lisboa Faculdade de Ciências, Portugal
Fundação para a Ciência e a Tecnologia
Produções

Publicações

Artigo em conferência
  1. Perdigão, João; Silva, Carla; Diniz, Jaciara; Pereira, Catarina; Machado, Diana; Ramos, Jorge; Silva, Hugo; et al. "Mycobacterium tuberculosis genetic diversity and drug resistance across Portuguese-speaking countries and CPLP-TB: a novel framework and surveillance tool for the Lusophone community". 2019.
  2. Sofia Santos Costa; Mafalda Rosa; Ana Catarina Rodrigues; Cláudia Mineiro Santos; Frederico Holtreman; Miguel Viveiros; Constança Pomba; Isabel Couto. "Emergence of non-wild-type populations towards biocides and antibiotic resistance in Staphylococcus epidermidis colonizing veterinary staff and students". 2018.
  3. Costa, SS; Kadlec, Kristina; Viveiros, Miguel; Melo Cristino, José; Schwarz, Stefan; Couto, Isabel. "Complete sequences of two Staphylococcus aureus plasmids carrying genes for resistance to antibiotics, heavy-metals, biocides and/or virulence". 2018.
  4. Santos Costa, Sofia; Santos, Cláudia Mineiro; Viveiros, Miguel; Pomba, Constança. "Frequent biofilm production by Staphylococcus epidermidis causing infection in pets or colonizing veterinary staff". 2018.
  5. Santos Costa, Sofia; Rosato, Adriana E.; Viveiros, Miguel; Couto, Isabel. "Development of multidrug resistance in staphylococci driven by efflux". 2018.
  6. Santos Costa, Sofia; Rosa, Mafalda; Belas, Adriana; Viveiros, Miguel; Pomba, Constança; Couto, Isabel. "Biocide susceptibility in Staphylococcus epidermidis causing infection in pets". 2018.
  7. Sofia Santos Costa; Mafalda Rosa; Ana Catarina Rodrigues; Frederico Holtreman; Miguel Viveiros; Constança Pomba; Isabel Couto. "Antibiotic and biocide resistance in Staphylococcus epidermidis colonizing humans in close contact with animals". 2017.
  8. Isabel Couto; Sofia Santos Costa; Diana Machado; Miguel Viveiros. "Microbial multiresistance in the era of global challenges – an urgent need for new approaches and technologies". 2017.
  9. Santos, Cláudia Mineiro; Costa, SS; Viveiros, Miguel; Pomba, Constança; Couto, I. "Prevalence of biofilm production in Staphylococcus epidermidis colonizing veterinary staff and students". 2017.
  10. Costa, SS; Rosa, Mafalda; Rodrigues, Ana Catarina; Holtreman, Frederico; Viveiros, Miguel; Pomba, Constança; Couto, I. "Antibiotic and biocide resistance in Staphylococcus epidermidis colonizing humans in close contact with animals". 2017.
  11. Holtreman, Frederico; Costa, SS; Rosa, Mafalda; Viveiros, Miguel; Pomba, Constança; Couto, I. "Characterization of plasmid encoded efflux determinants from Staphylococcus epidermidis". 2017.
  12. Costa, SS; Rosa, Mafalda; Rodrigues, Ana Catarina; Santos, Cláudia Mineiro; Holtreman, Frederico; Viveiros, Miguel; Pomba, Constança; Couto, I. "Characterization of antimicrobial resistance in Staphylococcus epidermidis colonizing veterinary staff and students". 2017.
  13. Diana Machado; Elisa Azzali; Sofia Santos Costa; Gabriele Costantino; Isabel Couto; Marco Pieroni; Miguel Viveiros. "Antimycobacterial and efflux inhibitory activity of 2-aminothiazole lead compound against Mycobacterium tuberculosis". 2016.
  14. Elizeth Lopes; Sofia Santos Costa; Diana Machado; Marco Pieroni; Elisa Azzali; Gabriele Costantino; Miguel Viveiros; Isabel Couto. "Mycobacterium smegmatis model for the rapid screening of new compounds with efflux inhibitory and antimycobacterial activity". 2015.
  15. Perdigão, João; Clemente, Sofia; Ramos, Jorge; Masakidi, Pedro; Machado, Diana; Silva, Carla; Couto, Isabel; et al. "Drug resistance and genetic diversity of Mycobacterium tuberculosis in Luanda, Angola: a molecular epidemiological perspective". 2015.
  16. Sofia Santos Costa; Elisabete Junqueira; Cláudia Palma; Miguel Viveiros; Josè Melo-Cristino; Leonard Amaral; Isabel Couto. "Clinical relevance of efflux systems to antimicrobial resistance in Staphylococcus aureus". 2013.
  17. Leonard Amaral; Miguel Viveiros; Alexandru, T; Pascu, ML; Danko, B; Nastasa, V; Boni, M; et al. "Generation and biological evaluation of the pproducts formed from the exposure of phenothiazine to a 266 nm laser beam.". 2013.
    10.1117/12.2032666
  18. Perdigao, joão; Macedo, Rita; Machado, Diana; Silva, Carla; Jordão, Luísa; Couto, Isabel; Viveiros, Miguel; Portugal, Isabel. "Correlation between streptomycin intermediate-level resistance and gidB mutation in an endemic multidrugresistant tuberculosis cluster". 2013.
  19. Perdigão, João; Macedo, Rita; Machado, Diana; Silva, Carla; Jordão, Luísa; Couto, Isabel; Viveiros, Miguel; Portugal, Isabel. "Polymorphism in gidB gene as a genetic marker for the mycobacterium tuberculosis Q1 cluster and implications for the streptomycin resistance level". 2013.
  20. Perdigao, Joao; Silva, D.; Pereira, V.; Macedo, Rita; Silva, Carla; Machado, Diana; Couto, Isabel; et al. "Dynamics and Development of Extensively Drug-resistant Tuberculosis, Portugal". 2012.
  21. Silva, Carla; Perdigão, João; Couto, Isabel; Viveiros, Miguel; Jordão, Luísa; Portugal, Isabel. "Deletion analysis on multidrug resistant Mycobacterium tuberculosis in Portugal". 2011.
  22. Leonard Amaral; Gabriella Spengler; Liliana Rodrigues; Ana Martins; Marta Martins; Sofia Santos Costa; Isabel Couto; Miguel Viveiros. "Efflux pumps of bacteria and cancer cells". 2010.
  23. Costa, SS; Couto, I; Viveiros, Miguel; Martins, Marta; Leandro, Clara; Amaral, Leonard. "Characterization of reduced susceptibility to biocides, dyes, and quinolones in a Staphylococcus aureus strain exposed to ethidium bromide". 2007.
Artigo em revista
  1. Tatiana Tozar; Sofia Santos Costa; Ana Maria Udrea; Viorel Nastasa; Isabel Couto; Miguel Viveiros; Mihail Lucian Pascu; Mihaela Oana Romanitan. "Anti-staphylococcal activity and mode of action of thioridazine photoproducts". Scientific Reports Vol. 10 n.º 1 (2020): 18043-18055. https://novaresearch.unl.pt/en/publications/7f6bf3c7-512d-4cc3-b0e3-b9942d360c3a.
    10.1038/s41598-020-74752-z
  2. Viveiros, Miguel. "Using genomics to understand the origin and dispersion of multidrug and extensively drug resistant tuberculosis in Portugal". Scientific Reports (2020): http://dx.doi.org/10.1038/s41598-020-59558-3.
    10.1038/s41598-020-59558-3
  3. João Perdigão; Carla Quintão; Fernando Maltez; Diana Machado; Anabela Miranda; Isabel Couto; Paulo Rabna; et al. "Emergence of multidrug-resistant Mycobacterium tuberculosis of the Beijing lineage in Portugal and Guinea-Bissau: a snapshot of moving clones by whole-genome sequencing". Emerging microbes & infections Vol. 9 n.º 1 (2020): 1342-1353. https://novaresearch.unl.pt/en/publications/997d4a3c-12af-4798-9249-b96d29a2d325.
    10.1080/22221751.2020.1774425
  4. Verza M; Scheffer MC; Salvato RS; Schorner MA; Barazzetti FH; de Melo Machado H; Medeiros TF; et al. "Author Correction: Genomic epidemiology of Mycobacterium tuberculosis in Santa Catarina, Southern Brazil.". Scientific reports (2020): http://europepmc.org/abstract/med/33139782.
    10.1038/s41598-020-76386-7
  5. Schön T; Werngren J; Machado D; Borroni E; Wijkander M; Lina G; Mouton J; et al. "Multicentre testing of the EUCAST broth microdilution reference method for MIC determination on Mycobacterium tuberculosis.". Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases (2020): http://europepmc.org/abstract/med/33198949.
    10.1016/j.cmi.2020.10.019
  6. Frédéric Méchaï; Hugues Cordel; Lorenzo Guglielmetti; Alexandra Aubry; Mateja Jankovic; Miguel Viveiros; Miguel Santin; et al. "Management of Tuberculosis". Frontiers in public health 8 (2020): https://novaresearch.unl.pt/en/publications/cfe4d982-d6f5-455e-9a1f-91cd5f580ec8.
    10.3389/fpubh.2020.00443
  7. Tavares A; Pingarilho M; Batista J; Viveiros M; Dias S; Toscano C; Gomes P; Abecasis AB. "HIV and tuberculosis co-infection among migrants in Portugal: a brief study on their sociodemographic, clinical, and genomic characteristics.". AIDS research and human retroviruses (2020): http://europepmc.org/abstract/med/32962419.
    10.1089/aid.2020.0119
  8. Thomas Schön; Jim Werngren; Diana Machado; Emanuele Borroni; Maria Wijkander; Gerard Lina; Johan Mouton; et al. "Antimicrobial susceptibility testing of Mycobacterium tuberculosis complex isolates". Clin. Microbiol. Infect Supl. 1198 n.º 20 (2020): 30444-30465. https://novaresearch.unl.pt/en/publications/6058800c-bdc4-464b-9cba-9edb82ab1942.
    10.1016/j.cmi.2020.07.036.
  9. Schön T; Köser CU; Werngren J; Viveiros M; Georghiou S; Kahlmeter G; Giske C; et al. "What is the role of the EUCAST reference method for MIC testing of the Mycobacterium tuberculosis complex?". Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases (2020): http://europepmc.org/abstract/med/32768492.
    10.1016/j.cmi.2020.07.037
  10. Min Ong CW; Migliori GB; Raviglione M; MacGregor-Skinner G; Sotgiu G; Alffenaar JW; Tiberi S; et al. "Epidemic and pandemic viral infections: impact on tuberculosis and the lung. A consensus by the World Association for Infectious Diseases and Immunological Disorders (WAidid), Global Tuberculosis Network (GTN) and members# of ESCMID Study Group for Mycobacterial Infections (ESGMYC).". The European respiratory journal (2020): http://europepmc.org/abstract/med/32586885.
    10.1183/13993003.01727-2020
  11. Verza M; Scheffer MC; Salvato RS; Schorner MA; Barazzetti FH; Machado HM; Medeiros TF; et al. "Genomic epidemiology of Mycobacterium tuberculosis in Santa Catarina, Southern Brazil.". Scientific reports (2020): http://europepmc.org/abstract/med/32732910.
    10.1038/s41598-020-69755-9
  12. Liliana Rodrigues; Pedro Cravo; Miguel Viveiros. "Efflux pump inhibitors as a promising adjunct therapy against drug resistant tuberculosis: a new strategy to revisit mycobacterial targets and repurpose old drugs". Expert Review of Anti-infective Therapy (2020): https://doi.org/10.1080/14787210.2020.1760845.
    10.1080/14787210.2020.1760845
  13. Bruno C. Gomes; Mónica Honrado; Ana Armada; Miguel Viveiros; José Rueff; António S. Rodrigues. "ABC Efflux Transporters and the Circuitry of miRNAs: Kinetics of Expression in Cancer Drug Resistance". International Journal of Molecular Sciences (2020): https://doi.org/10.3390/ijms21082985.
    10.3390/ijms21082985
  14. Richard Steiner Salvato; Elis Regina Dalla Costa; Ana Júlia Reis; Sun Hee Schiefelbein; Maria Laura Halon; Regina Bones Barcellos; Gisela Unis; et al. "First insights into circulating XDR and pre-XDR Mycobacterium tuberculosis in Southern Brazil". Infection, Genetics and Evolution 78 (2020): 104127-104127. https://doi.org/10.1016/j.meegid.2019.104127.
    10.1016/j.meegid.2019.104127
  15. Neves CP; Costa AG; Safe IP; de Souza Brito A; Jesus JS; Kritski AL; Lacerda MVG; Viveiros M; Cordeiro-Santos M. "The role of mini-bronchoalveolar lavage fluid in the diagnosis of pulmonary tuberculosis in critically ill patients.". BMC Infectious Diseases (2020): http://europepmc.org/abstract/med/32188399.
    10.1186/s12879-020-04954-3
  16. Borsoi AF; Paz JD; Abbadi BL; Macchi FS; Sperotto N; Pissinate K; Rambo RS; et al. "Design, synthesis, and evaluation of new 2-(quinoline-4-yloxy)acetamide-based antituberculosis agents.". European journal of medicinal chemistry (2020): http://europepmc.org/abstract/med/32113048.
    10.1016/j.ejmech.2020.112179
  17. Méchaï F; Cordel H; Guglielmetti L; Aubry A; Jankovic M; Viveiros M; Santin M; Goletti D; Cambau E. "Management of Tuberculosis: Are the Practices Homogeneous in High-Income Countries?". Frontiers in public health (2020): http://europepmc.org/abstract/PMC/PMC7509453.
  18. Silvana Miranda; Isabela Almeida; Maria Mansur; Lida Figueredo; Wânia Carvalho; João Hadaad; Jaciara Diniz; et al. "Detection of drug resistant Mycobacterium tuberculosis strains using Kit SIRE Nitratase". Brazilian Archives of Biology and Technology Vol. 63 (2020): e20190179-e20190188. https://novaresearch.unl.pt/en/publications/4fc5a85d-c2bb-48da-9b8d-9da720ec66a6.
    https://doi.org/10.1590/1678-4324-2020190179
  19. Silvana Spindola de Miranda; Isabela Neves de Almeida; Maria de Fátima Filardi Oliveira Mansur; Lida Jouca de Assis Figueredo; Wânia da Silva Carvalho; João Paulo Amaral Hadaad; Jaciara de Lourdes do Carmo Guimarães Diniz; et al. "Detection of drug resistant mycobacterium tuberculosis strains using kit SIRE nitratase®". Brazilian Archives Of Biology And Technology 63 (2020): 1-9. https://novaresearch.unl.pt/en/publications/04f7768b-3da4-43d5-8514-9a45c7059216.
    10.1590/1678-4324-2020190179
  20. Gomes, Bruno C.; Honrado, Mónica; Armada, Ana; Viveiros, Miguel; Rueff, José; Rodrigues, António S.. "ABC Efflux Transporters and the Circuitry of miRNAs". (2020): http://hdl.handle.net/10362/97345.
    10.3390/ijms21082985Scopus
  21. Vieira ML; Liliana Rodrigues; Fernando Almeida; Filomeno Fortes; Sousa, Germano de; Monteiro, Sandra; Henrique Silveira; Miguel Viveiros. "O contributo dos serviços de diagnóstico laboratorial para o acesso universal à saúde nos países da Comunidade de Língua Portuguesa". Anais do Instituto de Higiene e Medicina Tropical Vol. 18 (2019): 42-51. https://novaresearch.unl.pt/en/publications/1b0e72c7-7520-4e49-a756-9d825609d611.
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  23. Júlia S. Vianna; Diana Machado; Ivy B. Ramis; Fábia P. Silva; Dienefer V. Bierhals; Michael Andrés Abril; Andrea von Groll; et al. "The Contribution of Efflux Pumps in Mycobacterium abscessus Complex Resistance to Clarithromycin". Antibiotics (2019): https://doi.org/10.3390/antibiotics8030153.
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  24. Cá B; Fonseca KL; Sousa J; Maceiras AR; Machado D; Sanca L; Rabna P; et al. "Experimental Evidence for Limited in vivo Virulence of Mycobacterium africanum.". Frontiers in microbiology (2019): http://europepmc.org/abstract/med/31552007.
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  25. Tatara MB; Perdigão J; Viveiros M; Kritski A; Esther da Silva K; Correia Sacchi FP; Camioli de Lima C; Pereira Dos Santos PC; Andrade MKN. "Genetic Diversity and Molecular Epidemiology of Mycobacterium tuberculosis in Roraima State, Brazil.". The American journal of tropical medicine and hygiene (2019): http://europepmc.org/abstract/med/31392954.
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  26. Pena E; Machado D; Viveiros M; Jordão S. "A case report of disseminated Mycobacterium colombiense infection in an HIV patient.". International journal of mycobacteriology (2019): http://europepmc.org/abstract/med/31512608.
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  27. Phelan JE; O'Sullivan DM; Machado D; Ramos J; Oppong YEA; Campino S; O'Grady J; et al. "Integrating informatics tools and portable sequencing technology for rapid detection of resistance to anti-tuberculous drugs.". Genome medicine (2019): http://europepmc.org/abstract/med/31234910.
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  28. Irene Rossi; Francesca Buttini; Fabio Sonvico; Filippo Affaticati; Francesco Martinelli; Giannamaria Annunziato; Diana Machado; et al. "Sodium Hyaluronate Nanocomposite Respirable Microparticles to Tackle Antibiotic Resistance with Potential Application in Treatment of Mycobacterial Pulmonary Infections". Pharmaceutics (2019): https://doi.org/10.3390/pharmaceutics11050203.
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  29. Tavares AM; Garcia AC; Gama A; Abecasis AB; Viveiros M; Dias S. "Tuberculosis care for migrant patients in Portugal: a mixed methods study with primary healthcare providers.". BMC health services research (2019): http://europepmc.org/abstract/med/30999913.
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  30. Felicetti T; Machado D; Cannalire R; Astolfi A; Massari S; Tabarrini O; Manfroni G; et al. "Modifications on C6 and C7 positions of 3-phenylquinolone efflux pump inhibitors led to potent and safe anti-mycobacterial treatment adjuvants.". ACS infectious diseases (2019): http://europepmc.org/abstract/med/30907573.
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  31. Catarina Pereira; Pedro Gomes; Ricardo Taveira; Carla Silva; Fernando Maltez; Rita Macedo; Catarina Costa; et al. "Insights on the Mycobacterium tuberculosis population structure associated with migrants from Portuguese-speaking countries over a three-year period in greater Lisbon, Portugal: Implications at the public health level". Infection, Genetics and Evolution (2019): https://doi.org/10.1016/j.meegid.2019.03.025.
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  32. Oppong YEA; Phelan J; Perdigão J; Machado D; Miranda A; Portugal I; Viveiros M; Clark TG; Hibberd ML. "Genome-wide analysis of Mycobacterium tuberculosis polymorphisms reveals lineage-specific associations with drug resistance.". BMC genomics (2019): http://europepmc.org/abstract/med/30922221.
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  33. Bouceiro-Mendes R; Ortins-Pina A; Fraga A; Marques T; Viveiros M; Machado D; Soares-de-Almeida L; Freitas JP; Filipe P. "Mycobacterium marinum lymphocutaneous infection.". Dermatology online journal (2019): http://europepmc.org/abstract/med/30865411.
  34. Sofia Santos Costa; Benjamin Sobkowiak; Ricardo Parreira; Jonathan D. Edgeworth; Miguel Viveiros; Taane G. Clark; Isabel Couto. "Genetic Diversity of norA, Coding for a Main Efflux Pump of Staphylococcus aureus". Frontiers in Genetics 9 (2019): https://doi.org/10.3389%2Ffgene.2018.00710.
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  35. Júlia S. Vianna; Ivy B. Ramis; Dienefer Bierhals; Andrea von Groll; Daniela F. Ramos; Nilo Zanatta; Maria Cristina Lourenço; Miguel Viveiros; Pedro E.Almeida da Silva. "Tetrahydropyridine derivative as efflux inhibitor in Mycobacterium abscessus". Journal of Global Antimicrobial Resistance (2019): https://doi.org/10.1016/j.jgar.2018.12.020.
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  36. Ramis, I.B.; Vianna, J.S.; Silva Junior, L.; von Groll, A.; Ramos, D.F.; Zanatta, N.; Viveiros, M.; Silva, P.E.A.D.. "In silico and in vitro evaluation of tetrahydropyridine compounds as efflux inhibitors in Mycobacterium abscessus". Tuberculosis 118 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85069975225&partnerID=MN8TOARS.
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  37. Viveiros, Miguel. "Regulation of ABCB1 activity by microRNA-200c and microRNA-203a in breast cancer cells: the quest for microRNAs’ involvement in cancer drug resistance". Cancer Drug Resistance (2019): http://dx.doi.org/10.20517/cdr.2019.24.
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  38. Armada, Ana; Gomes, Bruno Costa; Viveiros, Miguel; Rueff, José; Rodrigues, António Sebastião; Instituto de Higiene e Medicina Tropical (IHMT); Global Health and Tropical Medicine (GHTM); NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM); Centre for Toxicogenomics and Human Health (ToxOmics). "Regulation of ABCB1 activity by microRNA-200c and microRNA-203a in breast cancer cells: the quest for microRNAs’ involvement in cancer drug resistance". (2019): https://cdrjournal.com/article/view/3114.
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  39. Vieira, Marisa Luísa; Rodrigues, Liliana; Almeida, Fernando; Fortes, Filomeno; de Sousa, Germano; Monteiro, Sandra; Silveira, Henrique; Viveiros, Miguel. "Laboratory services contribution to supporting public health and health services in Portuguese-speaking countries". (2019): http://anaisihmt.com/index.php/ihmt/article/view/337.
  40. R. Bouceiro-Mendes; A. Ortins-Pina; T. Marques; Miguel Viveiros; Diana Machado; L. Lito; J. Ferreira; et al. "A case report of multibacillary leprosy presenting with multiple outbreaks of erythema nodosum leprosum". Journal of the Portuguese Society of Dermatology and Venereology 77 1 (2019): 67–72-67–72. https://novaresearch.unl.pt/en/publications/8a92e91f-1688-481c-99d7-06cd5bea0d22.
  41. Vianna, Júlia S.; Machado, Diana; Ramis, Ivy B.; Silva, Fábia P.; Bierhals, Dienefer V.; Abril, Michael Andrés; Groll, Andrea von; et al. "The Contribution of efflux pumps in Mycobacterium abscessus complex resistance to clarithromycin". (2019): https://www.arca.fiocruz.br/handle/icict/36952.
  42. Diana Machado; Isabel Couto; Miguel Viveiros. "Advances in the molecular diagnosis of tuberculosis: From probes to genomes". Infection, Genetics and Evolution (2018): https://doi.org/10.1016/j.meegid.2018.11.021.
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  43. Alexandra S Simões; M. R. Maia; J. Gregorio; Isabel Couto; A. M. Asfeldt; G. S. Simonsen; Pedro Povoa; Miguel Viveiros; Luís Velez Lapão. "Participatory implementation of an antibiotic stewardship programme supported by an innovative surveillance and clinical decision-support system". Journal of Hospital Infection 100 3 (2018): 257-264. https://research.unl.pt/en/publications/participatory-implementation-of-an-antibiotic-stewardship-programme-supported-by-an-innovative-surveillance-and-clinical-decisionsupport-system(1b84098f-0e69-4114-b624-d8daea97b98c).html.
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  44. Luís Velez Lapão; Mélanie R. Maia; João Gregório; Isabel Couto; Pedro Povoa; Miguel Viveiros; Velez Lapao, L; et al. "Innovative Implementation of Antibiotic Stewardship supported by a Clinical Decision System". The European Journal of Public Health Vol. 28 supl. 4 (2018): 1-1. https://unl.elsevierpure.com/en/publications/3826e005-e0de-451d-b49a-e4bfb3322d20.
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  45. Diana Machado; Elisa Azzali; Isabel Couto; Gabriele Costantino; Marco Pieroni; Miguel Viveiros. "Adjuvant therapies against tuberculosis". Future Microbiology (2018): https://research.unl.pt/en/publications/adjuvant-therapies-against-tuberculosis(964db813-d647-41d0-a89c-258bcddf0314).html.
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  46. Benjamin Sobkowiak; Judith R. Glynn; Rein M.G.J. Houben; Kim Mallard; Jody E. Phelan; José Afonso Guerra-Assunção; Louis Banda; et al. "Identifying mixed Mycobacterium tuberculosis infections from whole genome sequence data". BMC Genomics 19 1 (2018): https://research.unl.pt/en/publications/identifying-mixed-mycobacterium-tuberculosis-infections-from-whole-genome-sequence-data(5a159068-38b7-4eea-bdec-dd88c0baad60).html.
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  47. Moisés Francisco; Sofia Santos Costa; Adriana Belas; Jorge Ramos; Isabel Couto; Constança Pomba; Miguel Viveiros. "First report on antimicrobial resistance and molecular characterisation of Salmonella enterica serotype Typhi isolated from human specimens in Luanda, Angola". Journal of Global Antimicrobial Resistance 13 (2018): 246-249. https://doi.org/10.1016/j.jgar.2018.02.001.
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  48. Ramis IB; Vianna JS; Reis AJ; von Groll A; Ramos DF; Viveiros M; da Silva PEA. "Antimicrobial and Efflux Inhibitor Activity of Usnic Acid Against Mycobacterium abscessus.". Planta medica (2018): http://europepmc.org/abstract/med/29913527.
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  49. Machado D; Antunes J; Simões A; Perdigão J; Couto I; McCusker M; Martins M; et al. "Contribution of efflux to colistin heteroresistance in a multidrug resistant Acinetobacter baumannii clinical isolate.". Journal of medical microbiology (2018): http://europepmc.org/abstract/med/29717972.
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  50. A. Tavares; A. Garcia; Abecasis AB; Miguel Viveiros; Sónia Dias. "Perspectives of health care providers in Portugal on the provision of care to migrant patients with TB or HIV-TB co-infection". European Journal of Public Health 28 (2018): 161-161. https://unl.elsevierpure.com/en/publications/88ef6e8e-51ed-4d48-a721-1c0950454fa7.
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  53. Diana Machado; João Perdigão; Isabel Portugal; Marco Pieroni; Pedro Silva; Isabel Couto; Miguel Viveiros. "Efflux Activity Differentially Modulates the Levels of Isoniazid and Rifampicin Resistance among Multidrug Resistant and Monoresistant Mycobacterium tuberculosis Strains". Antibiotics 7 1 (2018): 18-18. https://doi.org/10.3390/antibiotics7010018.
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  54. Perdigão J; Silva C; Diniz J; Pereira C; Machado D; Ramos J; Silva H; et al. "Clonal expansion across the seas as seen through CPLP-TB database: A joint effort in cataloguing Mycobacterium tuberculosis genetic diversity in Portuguese-speaking countries.". Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases (2018): http://europepmc.org/abstract/med/29559379.
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  56. Phelan J; de Sessions PF; Tientcheu L; Perdigao J; Machado D; Hasan R; Hasan Z; et al. "Methylation in Mycobacterium tuberculosis is lineage specific with associated mutations present globally.". Scientific reports (2018): http://europepmc.org/abstract/med/29317751.
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  57. Simões AS; Alves DA; Gregório J; Couto I; Dias S; Póvoa P; Viveiros M; Gonçalves L; Lapão LV. "Fighting antibiotic resistance in Portuguese Hospitals: understanding antibiotic prescription behaviors to better design antibiotic stewardship programs.". Journal of global antimicrobial resistance (2018): http://europepmc.org/abstract/med/29409949.
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  58. Costa, SS; Viveiros, M; Pomba, C; Couto, I. "Active antimicrobial efflux in Staphylococcus epidermidis: building up of resistance to fluoroquinolones and biocides in a major opportunistic pathogen". JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2018):
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  59. Machado, D; Lecorche, E; Mougari, F; Cambau, E; Viveiros, M. "Insights on Mycobacterium leprae Efflux Pumps and Their Implications in Drug Resistance and Virulence". FRONTIERS IN MICROBIOLOGY (2018):
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  62. Rolando Cannalire; Diana Machado; Tommaso Felicetti; Sofia Santos Costa; Serena Massari; Giuseppe Manfroni; Maria Letizia Barreca; et al. "Natural isoflavone biochanin A as a template for the design of new and potent 3-phenylquinolone efflux inhibitors against Mycobacterium avium". European Journal of Medicinal Chemistry 140 (2017): 321-330. https://research.unl.pt/en/publications/natural-isoflavone-biochanin-a-as-a-template-for-the-design-of-new-and-potent-3phenylquinolone-efflux-inhibitors-against-mycobacterium-avium(671a32ce-545c-4997-a030-d79c019e8eba).html.
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  63. Diogo Vila-Viçosa; Bruno L Victor; Jorge Ramos; Diana Machado; Miguel Viveiros; Jacek Switala; Peter C Loewen; et al. "Insights on the mechanism of action of INH-C10 as an antitubercular prodrug". Molecular pharmaceutics 14 12 (2017): https://research.unl.pt/en/publications/insights-on-the-mechanism-of-action-of-inhc10-as-an-antitubercular-prodrug(88307fd0-7d81-4ff4-b5ef-52ab3a17134d).html.
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  64. Yoshio Nakatani; Helen K Opel-Reading; Matthias Merker; Diana Machado; Sönke Andres; S Siva Kumar; Danesh Moradigaravand; et al. "Role of alanine racemase mutations in Mycobacterium tuberculosis D-cycloserine resistance". Antimicrobial Agents and Chemotherapy 61 12 (2017): https://research.unl.pt/en/publications/role-of-alanine-racemase-mutations-in-mycobacterium-tuberculosis-dcycloserine-resistance(ba3b15cd-2ab2-4c72-981d-1f70b4d99862).html.
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  65. Tavares, Ana Maria; Fronteira, Inês; Couto, Isabel; Machado, Diana; Viveiros, Miguel; Abecasis, Ana B.; Dias, Sónia; et al. "HIV and tuberculosis co-infection among migrants in Europe: A systematic review on the prevalence, incidence and mortality". PLOS ONE 12 9 (2017): e0185526. http://dx.doi.org/10.1371/journal.pone.0185526.
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  66. Elisa Azzali; Diana Machado; Amit Kaushik; Federica Vacondio; Sara Flisi; Clotilde Silvia Cabassi; Gyanu Lamichhane; et al. "Substituted N-Phenyl-5-(2-(phenylamino)thiazol-4-yl)isoxazole-3-carboxamides Are Valuable Antitubercular Candidates that Evade Innate Efflux Machinery". Journal Of Medicinal Chemistry (2017): 7108-7108. https://research.unl.pt/en/publications/substituted-nphenyl52phenylaminothiazol4ylisoxazole3carboxamides-are-valuable-antitubercular-candidates-that-evade-innate-efflux-machinery(897491b3-e688-47ad-8a5f-a8d8261f676a).html.
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  72. João Perdigão; Sofia Clemente; Jorge Ramos; Pedro Masakidi; Diana Machado; Carla Silva; Isabel Couto; et al. "Genetic diversity, transmission dynamics and drug resistance of Mycobacterium tuberculosis in Angola". Scientific Reports 7 1 (2017): 42814-42814. https://research.unl.pt/en/publications/genetic-diversity-transmission-dynamics-and-drug-resistance-of-mycobacterium-tuberculosis-in-angola(cba65502-3f10-4de0-b2cf-7b06d66c9450).html.
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  73. Ana Soares; Mónica S Estevão; M. Manuel B. Marques; Vasily Kovalishyn; Diogo A R S Latino; Joao Aires-de-Sousa; Jorge Ramos; Miguel Viveiros; Filomena Martins. "Synthesis and Biological Evaluation of Hybrid 1,5- and 2,5-Disubstituted Indoles as Potentially New Antitubercular Agents". Journal Of Medicinal Chemistry 13 5 (2017): 439-439. https://research.unl.pt/en/publications/synthesis-and-biological-evaluation-of-hybrid-15-and-25disubstituted-indoles-as-potentially-new-antitubercular-agents(b8ab96c2-2ef3-46d9-ad19-4d948f399fa3).html.
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  74. Bettencourt, Miguel. "Thioridazine: A Non-Antibiotic Drug Highly Effective, in Combination with First Line Anti-Tuberculosis Drugs, against Any Form of Antibiotic Resistance of Mycobacterium tuberculosis Due to Its Multi-Mechanisms of Action". Antibiotics (2017): http://www.mdpi.com/2079-6382/6/1/3.
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  76. Diana Machado; Tatiane S Coelho; João Perdigão; Catarina Pereira; Isabel Couto; Isabel Portugal; Raquel De Abreu Maschmann; et al. "Interplay between Mutations and Efflux in Drug Resistant Clinical Isolates of Mycobacterium tuberculosis". Frontiers in Microbiology 8 (2017): 711-711. https://research.unl.pt/en/publications/interplay-between-mutations-and-efflux-in-drug-resistant-clinical-isolates-of-mycobacterium-tuberculosis(26dcab5e-97f6-4c2b-a305-f0ece9e75609).html.
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  134. P. V. Baptista; Miguel Viveiros; Isabel Couto. "Isothermal DNA amplification coupled to Aunanoprobes for detection of mutations associated to Rifampicin resistance in Mycobacterium tuberculosis". Journal Of Nanobiotechnology 11 NA (2013): 38-38. https://research.unl.pt/en/publications/isothermal-dna-amplification-coupled-to-aunanoprobes-for-detection-of-mutations-associated-to-rifampicin-resistance-in-mycobacterium-tuberculosis(c1384fed-4794-4633-8b01-bbe0c27aedb0).html.
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  135. Leonard Amaral; Miguel Viveiros; Isabel Couto. "A simple method for assessment of MDR bacteria for over-expressed efflux pumps.". Open Microbiology Journal 7 NA (2013): 72-82. https://research.unl.pt/en/publications/a-simple-method-for-assessment-of-mdr-bacteria-for-overexpressed-efflux-pumps(d873b843-79f0-490f-80b4-0ea7808a6f2f).html.
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  136. Sofia Santos Costa; Miguel Viveiros; Leonard Amaral; Isabel Couto. "Multidrug efflux pumps in Staphylococcus aureus: an update.". Open Microbiology Journal 7 NA (2013): 59-71. https://research.unl.pt/en/publications/multidrug-efflux-pumps-in-staphylococcus-aureus-an-update(04af8331-c342-4bdb-8dde-3966a927d2bc).html.
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  137. Sofia Costa; Celeste Falcão; Miguel Viveiros; Diana Machado; Marta Martins; José Melo-Cristino; Leonard Amaral; Isabel Couto. "Correction: Exploring the contribution of efflux on the resistance to fluoroquinolones in clinical isolates of Staphylococcus aureus". BMC Microbiology 13 1 (2013): 127-127. http://dx.doi.org/10.1186/1471-2180-13-127.
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  138. Perdigão, joão; Macedo, Rita; Machado, Diana; Silva, Carla; Jordão, Luísa; Couto, Isabel; Viveiros, Miguel; Portugal, Isabel. "GidB mutation as a phylogenetic marker for Q1 cluster Mycobacterium tuberculosis isolates and intermediate-level streptomycin resistance determinant in Lisbon, Portugal". (2013): http://hdl.handle.net/10400.18/1769.
    1469-0691doi: 10.1111/1469-0691.12392
  139. Veigas, Bruno; Pedrosa, Pedro; Couto, Isabel; Viveiros, Miguel; Baptista, Pedro V.. "Isothermal DNA amplification coupled to Au-nanoprobes for detection of mutations associated to Rifampicin resistance in Mycobacterium tuberculosis". (2013): http://hdl.handle.net/10362/100686.
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  140. Miguel Viveiros; Rodrigo Martins; Pedro Barquinha; Elvira Fortunato; P. V. Baptista. "Gold on paper-paper platform for Au-nanoprobe TB detection". Lab On A Chip 12 22 (2012): 4802-8. https://research.unl.pt/en/publications/gold-on-paperpaper-platform-for-aunanoprobe-tb-detection(0a0a1763-9d4b-404b-8ee7-7dcb84d82ce6).html.
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  141. Liliana Rodrigues; Diana Machado; Isabel Couto; Leonard Amaral; Miguel Viveiros. "Contribution of efflux activity to isoniazid resistance in the Mycobacterium tuberculosis complex". Infection Genetics And Evolution 12 4 (2012): 695-700. https://research.unl.pt/en/publications/contribution-of-efflux-activity-to-isoniazid-resistance-in-the-mycobacterium-tuberculosis-complex(f2c4ea6f-0c4b-4e78-a4c7-bcf78a21bdfc).html.
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  142. Diana Machado; Isabel Couto; Liliana Rodrigues; P. V. Baptista; Bruno Veigas; Miguel Viveiros; Leonard Amaral. "Contribution of Efflux to the Emergence of Isoniazid and Multidrug Resistance in Mycobacterium tuberculosis.". Plos One 7 4 (2012): e34538-e34538. https://research.unl.pt/en/publications/contribution-of-efflux-to-the-emergence-of-isoniazid-and-multidrug-resistance-in-mycobacterium-tuberculosis(4f80727c-69c9-4c79-9e84-3a2fff2617e8).html.
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  143. Dymek A; Armada A; Handzlik J; Viveiros M; Spengler G; Molnar J; Kiec-Kononowicz K; Amaral L. "The activity of 16 new hydantoin compounds on the intrinsic and overexpressed efflux pump system of Staphylococcus aureus.". In Vivo (2012): http://europepmc.org/abstract/med/22351662.
  144. Leonard Amaral; Ana Martins; Miguel Viveiros; Isabel Couto; Sofia Santos Costa; Marta Martins. "Genetic response of Salmonella enterica serotype Enteritidis to thioridazine rendering the organism resistant to the agent.". International Journal Of Antimicrobial Agents 39 1 (2012): 16-21. https://research.unl.pt/en/publications/genetic-response-of-salmonella-enterica-serotype-enteritidis-to-thioridazine-rendering-the-organism-resistant-to-the-agent(9480871f-8741-4209-9d04-5f6377b5db67).html.
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  145. Miguel Viveiros; Leonard Amaral; Isabel Couto. "Inhibitors of mycobacterial efflux pumps as potential boosters for anti-tubercular drugs.". Expert Review Of Anti-Infective Therapy 10 9 (2012): 983-998. https://research.unl.pt/en/publications/inhibitors-of-mycobacterial-efflux-pumps-as-potential-boosters-for-antitubercular-drugs(268b7625-7450-4be5-abc3-32d4150d9b67).html.
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  146. Miguel Viveiros; Isabel Couto. "Using Au-nanoprobes por point-of-need diagnostics of TB.". Microbiologia online 1 (2012): online-online. https://research.unl.pt/en/publications/using-aunanoprobes-por-pointofneed-diagnostics-of-tb(f61729c0-46ff-4d34-aaae-12eda27028f1).html.
  147. Leonard Amaral; Miguel Viveiros. "Why thioridazine in combination with antibiotics cures extensively drug-resistant Mycobacterium tuberculosis infections". International Journal Of Antimicrobial Agents 39 5 (2012): 376-380. https://research.unl.pt/en/publications/why-thioridazine-in-combination-with-antibiotics-cures-extensively-drugresistant-mycobacterium-tuberculosis-infections(16d0c0ce-904f-4288-84be-2893850e785e).html.
    10.1016/j.ijantimicag.2012.01.012
  148. Rita Castro; J Costa; Isabel Couto; Vieira ML; Miguel Viveiros. "Infeções bacterianas negligenciadas, esquecidas ou desconhecidas? A tradição exótica do IHMT.". Anais Do Instituto De Higiene E Medicina Tropical 11 (2012): https://research.unl.pt/en/publications/infecoes-bacterianas-negligenciadas-esquecidas-ou-desconhecidas-a-tradicao-exotica-do-ihmt(e4d952d2-f650-4df6-924b-af14619c941f).html.
  149. Miguel Viveiros. "Edição Comemorativa dos Anais: O ensino das ciências médicas e biomédicas no Instituto de Higiene e Medicina Tropical – a contextualização histórico-pedagógica.". Anais Do Instituto De Higiene E Medicina Tropical 11 (2012): https://research.unl.pt/en/publications/edicao-comemorativa-dos-anais-o-ensino-das-ciencias-medicas-e-biomedicas-no-instituto-de-higiene-e-medicina-tropical--a-contextualizacao-historicopedagogica(62bb4661-2cc6-4c1d-aa6c-744cd463c70b).html.
  150. Perdigao, João; Macedo, Rita; Silva, Carla; Machado, Diana; Couto, Isabel; Viveiros, Miguel; Jordão, Luísa; Portugal, Isabel. "From multidrug-resistant to extensively drug-resistant tuberculosis in Lisbon, Portugal: the stepwise mode of resistance acquisition". (2012): http://hdl.handle.net/10400.18/1187.
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  151. Faculdade de Ciências. "Synthesis and thermochemical study of quinoxaline-N-oxides: enthalpies of dissociation of the N-O bond". (2012): 0894-3230.
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  152. Gabriella Spengler; Joseph Molnar; Miguel Viveiros; Leonard Amaral. "Thioridazine induces apoptosis of multidrug-resistant mouse lymphoma cells transfected with the human ABCB1 and inhibits the expression of P-glycoprotein". Anticancer Research 31 12 (2011): 4201-5. https://research.unl.pt/en/publications/thioridazine-induces-apoptosis-of-multidrugresistant-mouse-lymphoma-cells-transfected-with-the-human-abcb1-and-inhibits-the-expression-of-pglycoprotein(5fba65fc-e81c-4324-a696-0d117d45cc8b).html.
  153. Sofia Santos Costa; Celeste Falcão; Miguel Viveiros; Diana Machado; Marta Martins; José Melo-Cristino; Leonard Amaral; Isabel Couto. "Exploring the contribution of efflux on the resistance to fluoroquinolones in clinical isolates of Staphylococcus aureus". Bmc Microbiology 11 (2011): 241-241. https://research.unl.pt/en/publications/exploring-the-contribution-of-efflux-on-the-resistance-to-fluoroquinolones-in-clinical-isolates-of-staphylococcus-aureus(2d5a98ed-d260-4d76-bb02-5379b696ad01).html.
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  154. Spengler G; Handzlik J; Ocsovszki I; Viveiros M; Kiec-Kononowicz K; Molnar J; Amaral L. "Modulation of multidrug efflux pump activity by new hydantoin derivatives on colon adenocarcinoma cells without inducing apoptosis.". Anticancer research (2011): http://europepmc.org/abstract/med/21965738.
  155. Lisa Machado; Gabriella Spengler; Miguel Evaristo; Jadwiga Handzlik; Joseph Molnár; Miguel Viveiros; Katarzyna Kiec-Kononowicz; Leonard Amaral. "Biological activity of twenty-three hydantoin derivatives on intrinsic efflux pump system of Salmonella enterica serovar enteritidis NCTC 13349". In Vivo 25 5 (2011): 769-772. https://research.unl.pt/en/publications/biological-activity-of-twentythree-hydantoin-derivatives-on-intrinsic-efflux-pump-system-of-salmonella-enterica-serovar-enteritidis-nctc-13349(c1e82ed5-027d-4c99-91d8-52230b623f5a).html.
  156. Daniella Takács; Pedro Cerca; Ana Martins; Zsuzsanna Riedl; György Hajós; Joseph Molnár; Miguel Viveiros; Isabel Couto; Leonard Amaral. "Evaluation of forty new phenothiazine derivatives for activity against intrinsic efflux pump systems of reference Escherichia coli, Salmonella enteritidis, Enterococcus faecalis and Staphylococcus aureus strains". In Vivo 25 5 (2011): 719-724. https://research.unl.pt/en/publications/evaluation-of-forty-new-phenothiazine-derivatives-for-activity-against-intrinsic-efflux-pump-systems-of-reference-escherichia-coli-salmonella-enteritidis-enterococcus-faecalis-and-staphylococcus-aure(aa96152c-ac41-4.
  157. Martins M; Viveiros M; Couto I; Costa SS; Pacheco T; Fanning S; Pagès JM; Amaral L. "Identification of efflux pump-mediated multidrug-resistant bacteria by the ethidium bromide-agar cartwheel method.". In Vivo (2011): http://europepmc.org/abstract/med/21471531.
  158. Ana Martins; L, Machado; S. Costa; P, Cerca; G. Spengler; Miguel Viveiros; Leonard Amaral. "Role of calcium in the efflux system of Escherichia coli.". International Journal Of Antimicrobial Agents 37 5 (2011): 410-414. https://research.unl.pt/en/publications/role-of-calcium-in-the-efflux-system-of-escherichia-coli(865b70b0-2c27-45e6-95a5-d4660562156d).html.
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  159. P, Cerca; Ana Martins; Isabel Couto; Miguel Viveiros; Leonard Amaral. "Competition between substrates of the efflux pump system of Salmonella enteritidis.". In vivo (Athens, Greece) 25 4 (2011): 597-602. https://research.unl.pt/en/publications/competition-between-substrates-of-the-efflux-pump-system-of-salmonella-enteritidis(bbb3a9aa-0235-416f-8a8a-3cb30de45e45).html.
  160. Ana Martins; A. Vasas; Miguel Viveiros; J Molnár; J. Hohmann; Leonard Amaral. "Antibacterial properties of compounds isolated from Carpobrotus edulis.". International Journal Of Antimicrobial Agents 37 5 (2011): 438-444. https://research.unl.pt/en/publications/antibacterial-properties-of-compounds-isolated-from-carpobrotus-edulis(ebb51e70-14e4-4fff-be48-5c6b97fb6c2c).html.
    10.1016/j.ijantimicag.2011.01.016
  161. L, Rodrigues; J, Ramos; Isabel Couto; Leonard Amaral; Miguel Viveiros. "Ethidium bromide transport across Mycobacterium smegmatis cell-wall: correlation with antibiotic resistance.". Bmc Microbiology 11 NA (2011): 35-35. https://research.unl.pt/en/publications/ethidium-bromide-transport-across-mycobacterium-smegmatis-cellwall-correlation-with-antibiotic-resistance(a95c3627-3ddf-441d-b10a-df02f43c68d7).html.
    10.1186/1471-2180-11-35
  162. Leonard Amaral; M Martins; Miguel Viveiros. "Thioridazine: alternative and potentially effective therapy of the XDR-TB patient.". Letters In Drug Design & Discovery 8 2 (2011): 130-132. https://research.unl.pt/en/publications/thioridazine-alternative-and-potentially-effective-therapy-of-the-xdrtb-patient(5e02ba83-14ea-41aa-8114-cf005ef247b0).html.
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  163. Rodrigues, L.; Aínsa, J.A.; Amaral, L.; Viveiros, M.. "Inhibition of drug efflux in mycobacteria with phenothiazines and other putative efflux inhibitors". Recent Patents on Anti-Infective Drug Discovery 6 2 (2011): 118-127. http://www.scopus.com/inward/record.url?eid=2-s2.0-79960065506&partnerID=MN8TOARS.
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  164. Amaral, L.; Cerca, P.; Spengler, G.; MacHado, L.; Martins, A.; Couto, I.; Viveiros, M.; Fanning, S.; Pags, J.-M.. "Ethidium bromide efflux by Salmonella: Modulation by metabolic energy, pH, ions and phenothiazines". International Journal of Antimicrobial Agents 38 2 (2011): 140-145. http://www.scopus.com/inward/record.url?eid=2-s2.0-79959759805&partnerID=MN8TOARS.
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  165. Pascu, M.-L.; Nastasa, V.; Smarandache, A.; Militaru, A.; Martins, A.; Viveiros, M.; Boni, M.; et al. "Direct modification of bioactive phenothiazines by exposure to laser radiation". Recent Patents on Anti-Infective Drug Discovery 6 2 (2011): 147-157. http://www.scopus.com/inward/record.url?eid=2-s2.0-79959994231&partnerID=MN8TOARS.
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  166. Amara, L.; Viveiros, M.; Molnar, J.; Kristiansen, J.E.. "Effective therapy with the neuroleptic thioridazine as an adjunct to second line of defence drugs, and the potential that thioridazine offers for new patents that cover a variety of ''New Uses''". Recent Patents on Anti-Infective Drug Discovery 6 2 (2011): 84-87. http://www.scopus.com/inward/record.url?eid=2-s2.0-79959996814&partnerID=MN8TOARS.
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  167. Ramalhete, C.; Spengler, G.; Martins, A.; Martins, M.; Viveiros, M.; Mulhovo, S.; Ferreira, M.-J.U.; Amaral, L.. "Inhibition of efflux pumps in meticillin-resistant Staphylococcus aureus and Enterococcus faecalis resistant strains by triterpenoids from Momordica balsamina". International Journal of Antimicrobial Agents 37 1 (2011): 70-74. http://www.scopus.com/inward/record.url?eid=2-s2.0-78650262885&partnerID=MN8TOARS.
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  168. Kristiansen JE; Thomsen VF; Martins A; Viveiros M; Amaral L. "Non-antibiotics reverse resistance of bacteria to antibiotics.". In Vivo (2010): http://europepmc.org/abstract/med/20952744.
  169. A. Martins; A. Vasas; Z. S. Schelz; Miguel Viveiros; Joseph Molnar; J. Hohmann; L. Amaral. "Constituents of Carpobrotus edulis Inhibit P-Glycoprotein of MDR1-transfected Mouse Lymphoma Cells". Anticancer Research 30 3 (2010): 829-835. https://research.unl.pt/en/publications/constituents-of-carpobrotus-edulis-inhibit-pglycoprotein-of-mdr1transfected-mouse-lymphoma-cells(7a37d487-12e5-497a-a2c2-3dbae69ac091).html.
  170. Leonard Amaral; Miguel Viveiros. "Biological Activity of Hydantoin Derivatives on P-Glycoprotein (ABCB1) of Mouse Lymphoma Cells.". Anticancer Research 30 12 (2010): 4867-4871. https://research.unl.pt/en/publications/biological-activity-of-hydantoin-derivatives-on-pglycoprotein-abcb1-of-mouse-lymphoma-cells(f1af5fe1-fd80-4a7a-9b80-9637a5c7d7f6).html.
  171. Leonard Amaral; A, Martins; J, Molnár; JE, Kristiansen; M, Martins; Miguel Viveiros; L, Rodrigues; et al. "Thioridazine cures extensively drug-resistant tuberculosis (XDR-TB) and the need for global trials is now!". International Journal Of Antimicrobial Agents 35 6 (2010): 524-6. https://research.unl.pt/en/publications/thioridazine-cures-extensively-drugresistant-tuberculosis-xdrtb-and-the-need-for-global-trials-is-now(74bcade5-7cd5-4922-b3fc-97944065d5c6).html.
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  172. J, Chevalier; A, Mahamoud; M, Baitiche; E, Adam; Miguel Viveiros; A, Smarandache; A, Militaru; et al. "Quinazoline derivatives are efficient chemosensitizers of antibiotic activity in Enterobacter aerogenes, Klebsiella pneumoniae and Pseudomonas aeruginosa resistant strains.". International Journal Of Antimicrobial Agents 36 2 (2010): 164-168. https://research.unl.pt/en/publications/quinazoline-derivatives-are-efficient-chemosensitizers-of-antibiotic-activity-in-enterobacter-aerogenes-klebsiella-pneumoniae-and-pseudomonas-aeruginosa-resistant-strains(fc26a076-2106-4cbf-81f1-83515193e57b).html.
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  173. Leonard Amaral; Isabel Couto; Miguel Viveiros. "Phenothiazines, bacterial efflux pumps and targeting the macrophage for enhanced killing of intracellular XDRTB.". In Vivo 24 4 (2010): 409-24. https://research.unl.pt/en/publications/phenothiazines-bacterial-efflux-pumps-and-targeting-the-macrophage-for-enhanced-killing-of-intracellular-xdrtb(4dceb97c-78b6-4568-8a08-17eee159d483).html.
  174. Miguel Viveiros; M Martins; Isabel Couto; L Rodrigues; Diana Machado; I, Portugal; Leonard Amaral. "Molecular tools for rapid identification and novel effective therapy against MDRTB/XDRTB infections.". Expert Review Of Anti-Infective Therapy 8 4 (2010): 465-80. https://research.unl.pt/en/publications/molecular-tools-for-rapid-identification-and-novel-effective-therapy-against-mdrtbxdrtb-infections(1a6357bd-6bd7-42d9-8971-fef672c368aa).html.
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  175. Isabel Couto; Diana Machado; Miguel Viveiros; L, Rodrigues; Leonard Amaral. "Identification of nontuberculous mycobacteria in clinical samples using molecular methods: a 3-year study.". Clinical Microbiology and Infection 16 8 (2010): 1161-4. https://research.unl.pt/en/publications/identification-of-nontuberculous-mycobacteria-in-clinical-samples-using-molecular-methods-a-3year-study(9f3654d8-6af6-40c2-a10d-5885a74e643f).html.
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  176. Leonard Amaral; Isabel Couto; Miguel Viveiros. "Physiological characterisation of the efflux pump system of antibiotic-susceptible and multidrug-resistant Enterobacter aerogenes.". International Journal Of Antimicrobial Agents 36 4 (2010): 313-318. https://research.unl.pt/en/publications/physiological-characterisation-of-the-efflux-pump-system-of-antibioticsusceptible-and-multidrugresistant-enterobacter-aerogenes(476a7457-e521-4833-a63d-da9839b03b42).html.
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  177. Isabel Couto; Miguel Viveiros; P. V. Baptista. "Au-nanoprobes for detection of SNPs associated with antibiotic resistance in Mycobacterium tuberculosis.". Nanotechnology 21 41 (2010): 415101-415101. https://research.unl.pt/en/publications/aunanoprobes-for-detection-of-snps-associated-with-antibiotic-resistance-in-mycobacterium-tuberculosis(410472c4-7c42-4661-8721-34d5c9f1a879).html.
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  178. Sofia Santos Costa; E, Ntokou; A, Martins; Miguel Viveiros; S, Pouranas; Leonard Amaral; Isabel Couto. "Identification of the plasmid-encoded qacA efflux pump gene in meticillin-resistant Staphylococcus aureus (MRSA) strain HPV107, a representative of the MRSA Iberian clone.". International Journal Of Antimicrobial Agents 36 6 (2010): 557-61. https://research.unl.pt/en/publications/identification-of-the-plasmidencoded-qaca-efflux-pump-gene-in-meticillinresistant-staphylococcus-aureus-mrsa-strain-hpv107-a-representative-of-the-mrsa-iberian-clone(3b723a33-fb4e-40ee-b1b8-dab03bbc7b78).html.
    10.1016/j.ijantimicag.2010.08.006
  179. Miguel Viveiros; Liliana Rodrigues; Marta Martins; Isabel Couto; Gabriella Spengler; Ana Martins; Leonard Amaral. "Evaluation of efflux activity of bacteria by a semi-automated fluorometric system". Methods In Molecular Biology (Clifton, N.J.) 642 (2010): 159-72. https://research.unl.pt/en/publications/evaluation-of-efflux-activity-of-bacteria-by-a-semiautomated-fluorometric-system(3e302ca5-1108-4948-b7c4-16c82c7f9ad4).html.
    10.1007/978-1-60327-279-7_12
  180. Marta Martins; Miguel Viveiros; Diane Ordway; Jette E. Kristiansen; Joseph Molnar; Leonard Amaral. "Reserpine, ouabain and the calcium channel blocker verapamil, cause intracellular killing of Staphylococcus aureus". Research Journal of Microbiology 5 6 (2010): 490-496. https://research.unl.pt/en/publications/reserpine-ouabain-and-the-calcium-channel-blocker-verapamil-cause-intracellular-killing-of-staphylococcus-aureus(29ea7e83-8af4-4d2a-8b37-0876c0f8aac4).html.
    10.3923/jm.2006.203.209
  181. Martins, M.; Couto, I.; Viveiros, M.; Amaral, L.. "Identification of efflux-mediated multi-drug resistance in bacterial clinical isolates by two simple methods.". Methods in molecular biology (Clifton, N.J.) 642 (2010): 143-157. http://www.scopus.com/inward/record.url?eid=2-s2.0-77954672260&partnerID=MN8TOARS.
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  182. Martins A; Spengler G; Rodrigues L; Viveiros M; Ramos J; Martins M; Couto I; et al. "pH Modulation of efflux pump activity of multi-drug resistant Escherichia coli: protection during its passage and eventual colonization of the colon.". PloS one (2009): http://europepmc.org/abstract/med/19684858.
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  183. Spengler G; Viveiros M; Martins M; Rodrigues L; Martins A; Molnar J; Couto I; Amaral L. "Demonstration of the activity of P-glycoprotein by a semi-automated fluorometric method.". Anticancer research (2009): http://europepmc.org/abstract/med/19528478.
  184. Gabriella Spengler; Ana Martins; Zsuzsanna Schelz; Liliana Rodrigues; Lone Aagaard; Marta Martins; Sofia Santos Costa; et al. "Characterization of intrinsic efflux activity of Enterococcus faecalis ATCC29212 by a semi-automated ethidium bromide method". In Vivo 23 1 (2009): 81-7. https://research.unl.pt/en/publications/characterization-of-intrinsic-efflux-activity-of-enterococcus-faecalis-atcc29212-by-a-semiautomated-ethidium-bromide-method(c61939f9-dbe3-4718-8929-fb0f970be727).html.
  185. Leonard Amaral; Miguel Viveiros; Isabel Couto. "An AcrAB-mediated multidrug-resistant phenotype is maintained following restoration of wild-type activities by efflux pump genes and their regulators". International Journal Of Antimicrobial Agents 34 6 (2009): 602-604. https://research.unl.pt/en/publications/an-acrabmediated-multidrugresistant-phenotype-is-maintained-following-restoration-of-wildtype-activities-by-efflux-pump-genes-and-their-regulators(f5824dcd-c5b1-46eb-af6c-e2eb636ad524).html.
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  186. Leonard Amaral; Miguel Viveiros; Isabel Couto. "Fluorometric determination of ethidium bromide efflux kinetics in Escherichia coli.". Journal Of Biological Engineering 3 NA (2009): 18-18. https://research.unl.pt/en/publications/fluorometric-determination-of-ethidium-bromide-efflux-kinetics-in-escherichia-coli(9a66e485-80b4-4a1b-aec4-6bfa9060b9ba).html.
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  187. Leonard Amaral; Miguel Viveiros; Isabel Couto. "The role of efflux pumps in macrolide resistance in Mycobacterium avium complex". International Journal Of Antimicrobial Agents 34 6 (2009): 529-533. https://research.unl.pt/en/publications/the-role-of-efflux-pumps-in-macrolide-resistance-in-mycobacterium-avium-complex(0924160f-b4d4-41ed-868d-be68bb03c3e6).html.
    10.1016/j.ijantimicag.2009.07.010
  188. Miguel Viveiros; Leonard Amaral; Isabel Couto. "SILA 421, an inhibitor of efflux pumps of cancer cells, enhances the killing of intracellular extensively drug-resistant tuberculosis (XDR-TB)". International Journal Of Antimicrobial Agents 33 5 (2009): 479-482. https://research.unl.pt/en/publications/sila-421-an-inhibitor-of-efflux-pumps-of-cancer-cells-enhances-the-killing-of-intracellular-extensively-drugresistant-tuberculosis-xdrtb(bbfd06a7-9363-48df-b32f-59f8a2490489).html.
    10.1016/j.ijantimicag.2008.10.028
  189. Miguel Viveiros; Leonard Amaral; Isabel Couto. "Targeting human macrophages for enhanced killing of intracellular XDR-TB and MDR-TB.". International Journal Of Tuberculosis And Lung Disease 13 5 (2009): 569-73. https://research.unl.pt/en/publications/targeting-human-macrophages-for-enhanced-killing-of-intracellular-xdrtb-and-mdrtb(0abde695-e879-4be9-8b3f-ce2ddcd65080).html.
  190. Spengler, G.; Ramalhete, C.; Martins, M.; Martins, A.; Serly, J.; Viveiros, M.; Molnár, J.; et al. "Evaluation of cucurbitane-type triterpenoids from Momordica balsamina on P-glycoprotein (ABCB1) by flow cytometry and real-time fluorometry". Anticancer Research 29 10 (2009): 3989-3993. http://www.scopus.com/inward/record.url?eid=2-s2.0-71949083688&partnerID=MN8TOARS.
  191. Marta Martins; Miguel Viveiros; Leonard Amaral. "The TB laboratory of the future". Future Microbiology 3 2 (2008): 135-144. https://research.unl.pt/en/publications/the-tb-laboratory-of-the-future(3a9c3aef-56ef-4473-b0dd-f53a8016e980).html.
    10.2217/17460913.3.2.135
  192. Marta Martins; Miguel Viveiros; Leonard Amaral. "Inhibitors of Ca2+ and K+ transport enhance intracellular killing of M-tuberculosis by non-killing macrophages". In Vivo 22 1 (2008): 69-75. https://research.unl.pt/en/publications/inhibitors-of-ca2-and-k-transport-enhance-intracellular-killing-of-mtuberculosis-by-nonkilling-macrophages(1acf472d-2e82-4f36-8187-7fab48b71422).html.
  193. Viveiros, M; Martins, A; Paixao, L; Rodrigues, L; Martins, M; Couto, I; Faehnrich, E; Kern, WV; Amaral, L. "Demonstration of intrinsic efflux activity of Escherichia coli K-12 AG100 by an automated ethidium bromide method". INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2008):
    10.1016/j.ijantimicag.2007.12.015
  194. Martins, M.; Viveiros, M.; Amaral, L.. "Enhanced killing of intracellular pathogenic bacteria by phenothiazines and the role of K+ efflux pumps of the bacterium and the killing macrophage". Anti-Infective Agents in Medicinal Chemistry 7 1 (2008): 63-72. http://www.scopus.com/inward/record.url?eid=2-s2.0-41149156855&partnerID=MN8TOARS.
    10.2174/187152108783329807
  195. Martins, M.; Dastidar, S.G.; Fanning, S.; Kristiansen, J.E.; Molnar, J.; Pagès, J.-M.; Schelz, Z.; et al. "Potential role of non-antibiotics (helper compounds) in the treatment of multidrug-resistant Gram-negative infections: mechanisms for their direct and indirect activities". International Journal of Antimicrobial Agents 31 3 (2008): 198-208. http://www.scopus.com/inward/record.url?eid=2-s2.0-39149121434&partnerID=MN8TOARS.
    10.1016/j.ijantimicag.2007.10.025
  196. Rodrigues, L.; Wagner, D.; Viveiros, M.; Sampaio, D.; Couto, I.; Vavra, M.; Kern, W.V.; Amaral, L.. "Thioridazine and chlorpromazine inhibition of ethidium bromide efflux in Mycobacterium avium and Mycobacterium smegmatis". Journal of Antimicrobial Chemotherapy 61 5 (2008): 1076-1082. http://www.scopus.com/inward/record.url?eid=2-s2.0-42149168442&partnerID=MN8TOARS.
    10.1093/jac/dkn070
  197. Amaral, L.; Martins, M.; Viveiros, M.; Molnar, J.; Kristiansen, J.E.. "Promising therapy of XDR-TB/MDR-TB with thioridazine an inhibitor of bacterial efflux pumps". Current Drug Targets 9 9 (2008): 816-819. http://www.scopus.com/inward/record.url?eid=2-s2.0-52449123326&partnerID=MN8TOARS.
    10.2174/138945008785747798
  198. Couto, I.; Costa, S.S.; Viveiros, M.; Martins, M.; Amaral, L.. "Efflux-mediated response of Staphylococcus aureus exposed to ethidium bromide". Journal of Antimicrobial Chemotherapy 62 3 (2008): 504-513. http://www.scopus.com/inward/record.url?eid=2-s2.0-49649085104&partnerID=MN8TOARS.
    10.1093/jac/dkn217
  199. Marta Martins; Miguel Viveiros; Jette E. Kristiansen; Joseph Molnar; Leonard Amaral. "The curative activity of thioridazine on mice infected with Mycobacterium tuberculosis". In Vivo 21 5 (2007): 771-776. https://research.unl.pt/en/publications/the-curative-activity-of-thioridazine-on-mice-infected-with-mycobacterium-tuberculosis(ffeaa1b8-aaa8-4821-9cb4-a2eae377ae60).html.
  200. Noélia Duarte; Maria José U Ferreira; Marta Martins; Miguel Viveiros; Leonard Amaral. "Antibacterial activity of ergosterol peroxide against Mycobacterium tuberculosis". Phytotherapy Research 21 7 (2007): 601-604. https://research.unl.pt/en/publications/antibacterial-activity-of-ergosterol-peroxide-against-mycobacterium-tuberculosis(fc094880-9fe3-43d2-a9a0-d8558361b217).html.
    10.1002/ptr.2119
  201. Zsuzsanna Schelz; Marta Martins; Ana Martins; Miguel Viveiros; Joseph Molnar; Leonard Amaral. "Elimination of plasmids by SILA compounds that inhibit efflux pumps of bacteria and cancer cells". In Vivo 21 4 (2007): 635-640. https://research.unl.pt/en/publications/elimination-of-plasmids-by-sila-compounds-that-inhibit-efflux-pumps-of-bacteria-and-cancer-cells(dd5b8258-e90a-423e-8ca3-e15dffd8e0ca).html.
  202. Viveiros, M; Dupont, M; Rodrigues, L; Couto, I; Davin Regli, A; Martins, M; Pages, JM; Amaral, L. "Antibiotic Stress, Genetic Response and Altered Permeability of E. coli". PLOS ONE (2007):
    10.1371/journal.pone.0000365
  203. Amaral, L.; Engi, H.; Viveiros, M.; Molnar, J.. "Comparison of multidrug resistant efflux pumps of cancer and bacterial cells with respect to the same inhibitory agents". In Vivo 21 2 (2007): 237-244. http://www.scopus.com/inward/record.url?eid=2-s2.0-34047222991&partnerID=MN8TOARS.
  204. Amaral, L.; Martins, M.; Viveiros, M.. "Enhanced killing of intracellular multidrug-resistant Mycobacterium tuberculosis by compounds that affect the activity of efflux pumps". Journal of Antimicrobial Chemotherapy 59 6 (2007): 1237-1246. http://www.scopus.com/inward/record.url?eid=2-s2.0-34447542162&partnerID=MN8TOARS.
    10.1093/jac/dkl500
  205. Martins, M.; Schelz, Z.; Martins, A.; Molnar, J.; Hajös, G.; Riedl, Z.; Viveiros, M.; et al. "In vitro and ex vivo activity of thioridazine derivatives against Mycobacterium tuberculosis". International Journal of Antimicrobial Agents 29 3 (2007): 338-340. http://www.scopus.com/inward/record.url?eid=2-s2.0-33846969173&partnerID=MN8TOARS.
    10.1016/j.ijantimicag.2006.10.013
  206. Amaral, L.; Martins, M.; Viveiros, M.. "Phenothiazines as anti-multi-drug resistant tubercular agents". Infectious Disorders - Drug Targets 7 3 (2007): 257-265. http://www.scopus.com/inward/record.url?eid=2-s2.0-35649009444&partnerID=MN8TOARS.
    10.2174/187152607782110022
  207. Martins, A.; Couto, I.; Aagaard, L.; Martins, M.; Viveiros, M.; Kristiansen, J.E.; Amaral, L.. "Prolonged exposure of methicillin-resistant Staphylococcus aureus (MRSA) COL strain to increasing concentrations of oxacillin results in a multidrug-resistant phenotype". International Journal of Antimicrobial Agents 29 3 (2007): 302-305. http://www.scopus.com/inward/record.url?eid=2-s2.0-33846939351&partnerID=MN8TOARS.
    10.1016/j.ijantimicag.2006.10.012
  208. Duarte, Noelia; Ferreira, Maria-Jose U.; Martins, Marta; Viveiros, Miguel; Amaral, Leonard. "Antibacterial activity of ergosterol peroxide against Mycobacterium tuberculosis". (2007): http://hdl.handle.net/10451/21440.
    http://dx.doi.org/10.1002/ptr.2119
  209. Martins M; Santos B; Martins A; Viveiros M; Couto I; Cruz A; Pagès JM; et al. "An instrument-free method for the demonstration of efflux pump activity of bacteria.". In vivo (Athens, Greece) (2006): http://europepmc.org/abstract/med/17091774.
  210. Kristina Wolfart; Gabriella Spengler; Masami Kawase; Noboru Motohashi; Joseph Molnr; Miguel Viveiros; Leonard Amaral. "Synergistic interaction between proton pump inhibitors and resistance modifiers". In Vivo 20 3 (2006): 367-372. https://research.unl.pt/en/publications/synergistic-interaction-between-proton-pump-inhibitors-and-resistance-modifiers(740ea607-96a5-4fec-a406-7b990ba58100).html.
  211. Malthe M. Kristiansen; Clara Leandro; Diane Ordway; Marta Martins; Miguel Viveiros; Teresa Pacheco; Joseph Molnar; Jette E. Kristiansen; Leonard Amaral. "Thioridazine reduces resistance of methicillin-resistant Staphylococcus aureus by inhibiting a reserpine-sensitive efflux pump". In Vivo 20 3 (2006): 361-366. https://research.unl.pt/en/publications/thioridazine-reduces-resistance-of-methicillinresistant-staphylococcus-aureus-by-inhibiting-a-reserpinesensitive-efflux-pump(890b5163-3167-417a-a31f-a5a85c93cbe7).html.
  212. Amaral, L.; Viveiros, M.; Kristiansen, J.E.. ""Non-antibiotics": Alternative therapy for the management of MDRTB and MRSA in economically disadvantaged countries". Current Drug Targets 7 7 (2006): 887-891. http://www.scopus.com/inward/record.url?eid=2-s2.0-33745738994&partnerID=MN8TOARS.
    10.2174/138945006777709539
  213. Miguel Viveiros; Ana R. Jesus; Mafalda Brito; Clara Leandro; Marta Martins; Diane Ordway; Ana Maria Molnar; Joseph Molnar; Leonard Amaral. "Inducement and reversal of tetracycline resistance in Escherichia coli K-12 and expression of proton gradient-dependent multidrug efflux pump genes". Antimicrobial Agents and Chemotherapy -Journal- 49 8 (2005): 3578-3582. https://research.unl.pt/en/publications/inducement-and-reversal-of-tetracycline-resistance-in-escherichia-coli-k12-and-expression-of-proton-gradientdependent-multidrug-efflux-pump-genes(d09c3293-07b6-4d19-8115-6b4c2d8589a5).html.
    10.1128/aac.49.8.3578-3582.2005
  214. Miguel Viveiros; Marta Martins; Isabel Couto; Jette E. Kristiansen; Joseph Molnar; Leonard Amaral. "The in vitro activity of phenothiazines against Mycobacterium avium". In Vivo 19 4 (2005): 733-736. https://research.unl.pt/en/publications/the-in-vitro-activity-of-phenothiazines-against-mycobacterium-avium(fbdec778-4c28-4150-8719-f1d9b476b329).html.
  215. Diane J. Ordway; Miguel Viveiros; Fernando A. Ventura; Ian M. Orme; Hazel M. Dockrell; Leonard Amaral. "Exogenous Re-infection by Multiple Exposures to Mycobacterium tuberculosis Contributes to Subsequent Development of Active Tuberculosis". American Journal of Immunology 1 1 (2005): 42-47. http://dx.doi.org/10.3844/ajisp.2005.42.47.
    10.3844/ajisp.2005.42.47
  216. Marta Martins; Diane Ordway; Malthe M. Kristiansen; Miguel Viveiros; Clara Leandro; Joseph Molnar; Leonard Amaral. "Inhibition of the Carpobrotus edulis methanol extract on the growth of phagocytosed multidrug-resistant Mycobacterium tuberculosis and methicillin-resistant Staphylococcus aureus". Fitoterapia 76 1 (2005): 96-99. https://research.unl.pt/en/publications/inhibition-of-the-carpobrotus-edulis-methanol-extract-on-the-growth-of-phagocytosed-multidrugresistant-mycobacterium-tuberculosis-and-methicillinresistant-staphylococcus-aureus(3b85af21-61d8-4375-8c9c-83e5cf5bdbca)..
    10.1016/j.fitote.2004.09.020
  217. Viveiros, M; Leandro, C; Rodrigues, L; Almeida, J; Bettencourt, R; Couto, I; Carrilho, L; et al. "Direct application of the INNO-LiPA Rif.TB line-probe assay for rapid identification of Mycobacterium tuberculosis complex strains and detection of rifampin resistance in 360 smear-positive respiratory specimens from an area of high incidence of multidrug-resistant tuberculosis". JOURNAL OF CLINICAL MICROBIOLOGY (2005):
    10.1128/jcm.43.9.4880-4884.2005
  218. Ordway, DJ; Pinto, L; Costa, L; Martins, M; Leandro, C; Viveiros, M; Amaral, L; et al. "Gamma delta T cell responses associated with the development of tuberculosis in health care workers". FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY (2005):
    10.1016/j.femsim.2004.09.005
  219. Marta Martins; Wilfrid Bleiss; Anorte Marko; Diane Ordway; Miguel Viveiros; Clara Leandro; Teresa Pacheco; et al. "Clinical concentrations of thioridazine enhance the killing of intracellular methicillin-resistant Staphylococcus aureus". In Vivo 18 6 (2004): 787-794. https://research.unl.pt/en/publications/clinical-concentrations-of-thioridazine-enhance-the-killing-of-intracellular-methicillinresistant-staphylococcus-aureus(aa321791-8547-499f-b3e4-61f0edc19608).html.
  220. Amaral L; Viveiros M; Molnar J. "Antimicrobial activity of phenothiazines.". In vivo (Athens, Greece) (2004): http://europepmc.org/abstract/med/15646813.
  221. Malthe M. Kristiansen; Clara Leandro; Diane Ordway; Marta Martins; Miguel Viveiros; Teresa Pacheco; Jette E. Kristiansen; Leonard Amaral. "Phenothiazines alter resistance of methicillin-resistant strains of Staphylococcus aureus (MRSA) to oxacillin in vitro". International Journal Of Antimicrobial Agents 22 3 (2003): 250-253. https://research.unl.pt/en/publications/phenothiazines-alter-resistance-of-methicillinresistant-strains-of-staphylococcus-aureus-mrsa-to-oxacillin-in-vitro(580a0a3f-9b63-46a4-96da-d37f37a1b599).html.
    10.1016/s0924-8579(03)00200-0
  222. Diane Ordway; Miguel Viveiros; Clara Leandro; Rosário Bettencourt; Josefina Almeida; Marta Martins; Jette E. Kristiansen; Joseph Molnar; Leonard Amaral. "Clinical concentrations of thioridazine kill intracellular multidrug-resistant Mycobacterium tuberculosis". Antimicrobial Agents and Chemotherapy -Journal- 47 3 (2003): 917-922. https://research.unl.pt/en/publications/clinical-concentrations-of-thioridazine-kill-intracellular-multidrugresistant-mycobacterium-tuberculosis(74b76ec6-a5d5-4967-9a8e-b2cbf8729cdb).html.
    10.1128/aac.47.3.917-922.2003
  223. Ordway, D; Hohmann, J; Viveiros, M; Viveiros, A; Molnar, J; Leandro, C; Arroz, MJ; Gracio, MA; Amaral, L. "Carpobrotus edulis methanol extract inhibits the MDR efflux pumps, enhances killing of phagocytosed S-aureus and promotes immune modulation". PHYTOTHERAPY RESEARCH (2003):
    10.1002/ptr.1314
  224. Viveiros, M; Leandro, C; Amaral, L. "Mycobacterial efflux pumps and chemotherapeutic implications". INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2003):
    10.1016/s0924-8579(03)00208-5
  225. Grácio, M.A.; Dos Santos Grácio, A.J.; Viveiros, M.; Amaral, L.. "Since phenothiazines alter antibiotic susceptibility of microorganisms by inhibiting efflux pumps, are these agents useful for evaluating similar pumps in phenothiazine-sensitive parasites?". International Journal of Antimicrobial Agents 22 3 (2003): 347-351. http://www.scopus.com/inward/record.url?eid=2-s2.0-0042834382&partnerID=MN8TOARS.
    10.1016/s0924-8579(03)00204-8
  226. Diane Ordway; Miguel Viveiros; Clara Leandro; Maria Jorge Arroz; Joseph Molnar; Jette E. Kristiansen; Leonard Amaral. "Chlorpromazine has intracellular killing activity against phagocytosed Staphylococcus aureus at clinical concentrations". Journal of Infection and Chemotherapy 8 3 (2002): 227-231. https://research.unl.pt/en/publications/chlorpromazine-has-intracellular-killing-activity-against-phagocytosed-staphylococcus-aureus-at-clinical-concentrations(20f626b7-be04-42bf-bc20-d9de9b2a9909).html.
    10.1007/s10156-002-0188-4
  227. Ordway, D; Viveiros, M; Leandro, C; Arroz, MJ; Amaral, L. "Intracellular activity of clinical concentrations of phenothiazines including thioridiazine against phagocytosed Staphylococcus aureus". INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2002):
    10.1016/S0924-8579(02)00110-3
  228. Viveiros, M.; Portugal, I.; Bettencourt, R.; Victor, T.C.; Jordaan, A.M.; Leandro, C.; Ordway, D.; Amaral, L.. "Isoniazid-induced transient high-level resistance in Mycobacterium tuberculosis". Antimicrobial Agents and Chemotherapy 46 9 (2002): 2804-2810. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036719989&partnerID=MN8TOARS.
    10.1128/AAC.46.9.2804-2810.2002
  229. Amaral L; Kristiansen JE; Viveiros M; Atouguia J. "Activity of phenothiazines against antibiotic-resistant Mycobacterium tuberculosis: a review supporting further studies that may elucidate the potential use of thioridazine as anti-tuberculosis therapy.". The Journal of antimicrobial chemotherapy (2001): http://europepmc.org/abstract/med/11328759.
    10.1093/jac/47.5.505
  230. Miguel Viveiros; L Amaral; Viveiros, M; Amaral, L. "Enhancement of antibiotic activity against poly-drug resistant Mycobacterium tuberculosis by phenothiazines". International Journal Of Antimicrobial Agents 17 3 (2001): 225-228. https://research.unl.pt/en/publications/enhancement-of-antibiotic-activity-against-polydrug-resistant-mycobacterium-tuberculosis-by-phenothiazines(421d5e73-626f-4e33-9cce-de92d7ecf848).html.
    10.1016/s0924-8579(00)00343-5
  231. Amaral, L.; Viveiros, M.; Kristiansen, J.E.. "Phenothiazines: Potential alternatives for the management of antibiotic resistant infections of tuberculosis and malaria in developing countries". Tropical Medicine and International Health 6 12 (2001): 1016-1022. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035657318&partnerID=MN8TOARS.
    10.1046/j.1365-3156.2001.00804.x
  232. Miguel Viveiros; Suzana Bosne-David; Leonard Amaral. "Comparative in vitro activity of phenothiazines against multidrug- resistant Mycobacterium tuberculosis". International Journal Of Antimicrobial Agents 16 1 (2000): 69-71. https://research.unl.pt/en/publications/comparative-in-vitro-activity-of-phenothiazines-against-multidrug-resistant-mycobacterium-tuberculosis(3a4d1ea2-8f75-4af9-a2bf-c13eb2c5454b).html.
    10.1016/s0924-8579(00)00199-0
  233. Viveiros, M.; Krubasik, P.; Sandmann, G.; Houssaini-Iraqui, M.. "Structural and functional analysis of the gene cluster encoding carotenoid biosynthesis in Mycobacterium aurum A+". FEMS Microbiology Letters 187 1 (2000): 95-101. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034213794&partnerID=MN8TOARS.
    10.1016/S0378-1097(00)00182-8
  234. Miguel Viveiros; S. Pinheiro; Patrícia Raquel Moreira; Teresa Pacheco; Laura Maria Lourenço Brum da Cruz Martins. "Evaluation of a commercial ligase chain reaction assay for the diagnosis of pulmonary and extra-pulmonary tuberculosis". International Journal of Tuberculosis and Lung Disease 3 6 (1999): 508-514. https://research.unl.pt/en/publications/evaluation-of-a-commercial-ligase-chain-reaction-assay-for-the-diagnosis-of-pulmonary-and-extrapulmonary-tuberculosis(f32adb81-01f8-417d-82ca-555f263437d5).html.
  235. Portugal I; Covas MJ; Brum L; Viveiros M; Ferrinho P; Moniz-Pereira J; David H. "Outbreak of multiple drug-resistant tuberculosis in Lisbon: detection by restriction fragment length polymorphism analysis.". The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease (1999): http://europepmc.org/abstract/med/10094321.
  236. Graça Ribeiro; Miguel Viveiros; H. L. David; João V. Costa. "Mycobacteriophage D29 contains an integration system similar to that of the temperate mycobacteriophage L5". Microbiology-Sgm 143 8 (1997): 2701-2708. https://research.unl.pt/en/publications/mycobacteriophage-d29-contains-an-integration-system-similar-to-that-of-the-temperate-mycobacteriophage-l5(9858b247-c6d1-43b9-bbd0-a87dd1f10d8a).html.
    10.1099/00221287-143-8-2701
  237. Emília Prieto; Teresa Pacheco; Miguel Viveiros; Rosário Bettencourt; Laura Brum; Filomena Exposto. "Pesquisa de infecção micobacteriana em hemoculturas de doentes com SIDA, usando o sistema BACTEC 460TB". Revista Portuguesa de Pneumologia 2 6 (1996): 403-407. http://dx.doi.org/10.1016/s0873-2159(15)31178-8.
    10.1016/s0873-2159(15)31178-8
Capítulo de livro
  1. da Silva, PEA; Machado, D; Ramos, D; Couto, I; Von Groll, A; Viveiros, M. "Efflux Pumps in Mycobacteria: Antimicrobial Resistance, Physiological Functions, and Role in Pathogenicity". 2016.
    10.1007/978-3-319-39658-3_21
  2. Miguel Viveiros; Isabel Couto; Joao Inacio. "Diagnóstico Molecular". editado por {Barroso, 182-196. Lidel - Edi{\cc, 2014.
  3. Miguel Viveiros; Isabel Couto; ML, Rossetti; PA, da Silva. "Otimização, validação e controlo de qualidade de testes moleculares de diagnóstico". editado por {Cunha. Lidel - Edi{\cc, 2014.
  4. I, Portugal; Miguel Viveiros. "Mycobacterium". 316-331. Lidel - Edi{\cc, 2014.
  5. Miguel Viveiros; Leonard Amaral; Isabel Couto. "Therapy of the XDR-TB patients with thioridazine - an old drug with new applications.". 232-242. CABI, 2013.
  6. Miguel Viveiros; Isabel Couto; Leonard Amaral. "Improving on the LJ slope: automated liquid culture.". 34-45. CABI, 2013.
  7. Leonard Amaral; Ana Martins; Gabriella Spengler; Marta Martins; Liliana Rodrigues; Matthew McCusker; Eleni Ntokou; et al. "Structure, Genetic Regulation, Physiology and function of the acrab-tolc efflux pump of escherichia coli and salmonella". 44-61. CABI Publishing, 2012.
  8. Leonard Amaral; Séamus Fanning; Gabriella Spengler; L. Rodrigues; C. Iversen; M. Martins; A. Martins; et al. "Genetic regulation, physiology, assessment and inhibition of efflux pumps responsible for multi-drug resistant phenotypes of bacterial pathogens". editado por A Meszaros; G Balogh, 91-116. Nova Science Publishers, Inc., 2012.
  9. Miguel Viveiros. "Segurança em laboratórios de Microbiologia.". 587-609. Edi{\cc, 2010.
  10. Miguel Viveiros; Leonard Amaral; Isabel Couto. "One day identification of the md-rtb patient and proposed novel and effective therapy that is supported by extensive research.". 328 p.-328 p.. Nova science publishers, 2009.
Livro
  1. Armada, A.; Martins, C.; Spengler, G.; Molnar, J.; Amaral, L.; Rodrigues, A.S.; Viveiros, M.. Fluorimetric methods for analysis of permeability, drug transport kinetics, and inhibition of the ABCB1 membrane transporter. 2016.
    10.1007/978-1-4939-3347-1_7
  2. Rodrigues, L.; Viveiros, M.; Aínsa, J.A.. Measuring efflux and permeability in mycobacteria. 2015.
    10.1007/978-1-4939-2450-9_13
  3. Costa, P.; Couto, I.; Viveiros, M.; Inácio, J.. Nested and multiplex real-time PCR using dual-labeled probes: Detecting and discriminating Mycobacterium tuberculosis complex members in cultures and animal tissues. 2014.
    10.1007/978-1-4939-2004-4_9
Poster em conferência
  1. Liliana Rodrigues; Pedro Cravo; Miguel Viveiros. "Targeting membrane transporters and energy metabolism in Mycobacterium tuberculosis through in silico drug repurposing". 2020.
  2. Rute Ribeiro; Sofia Santos Costa; Constança Pomba; Miguel Viveiros. "Biocide and antibiotic resistance in Staphylococcus aureus causing skin and soft tissue infections in companion animals". 2019.
  3. Sofia Santos Costa; Patricia Abrantes; C Morais; Miguel Viveiros; Adriana E. Rosato; Isabel Couto. "Exploring the staphylococcal efflux-mediated response to ethidium bromide, an efflux pump substrate". 2019.
  4. Sofia Santos Costa; Patricia Abrantes; C Morais; Miguel Viveiros; Isabel Couto. "Exploring the efflux-driven multidrug resistance in staphylococci". 2019.
  5. Liliana Rodrigues; Pedro Cravo; Miguel Viveiros. "Chemogenomics and in silico repurposing as an innovative approach for rapid drug discovery in tuberculosis.". 2019.
  6. Sofia Santos Costa; Mafalda Rosa; Frederico Holtreman; Ana Catarina Rodrigues; Miguel Viveiros; Constança Pomba; Isabel Couto. "Emergence of non-wild-type populations towards biocides in Staphylococcus epidermidis colonizing veterinary staff". 2018.
  7. Sofia Santos Costa; Kristina Kadlec; Miguel Viveiros; Josè Melo-Cristino; Stefan Schwarz; Isabel Couto. "Complete sequences of two Staphylococcus aureus plasmids carrying genes for resistance to antibiotics, heavy-metals, biocides and/or virulence". 2018.
  8. Sofia Santos Costa; Adriana E. Rosato; Miguel Viveiros; Isabel Couto. "Development of multidrug resistance in staphylococci driven by efflux". 2018.
  9. Sofia Santos Costa; Mafalda Rosa; Adriana Belas; Miguel Viveiros; Constança Pomba; Isabel Couto. "Biocide susceptibility in Staphylococcus epidermidis causing infection in pets". 2018.
  10. Sofia Santos Costa; Cláudia Mineiro Santos; Miguel Viveiros; Constança Pomba. "Frequent biofilm production by Staphylococcus epidermidis causing infection in pets or colonizing veterinary staff". 2018.
  11. Sofia Santos Costa; Mafalda Rosa; Ana Catarina Rodrigues; Cláudia Mineiro Santos; Frederico Holtreman; Miguel Viveiros; Constança Pomba; Isabel Couto. "Characterization of antimicrobial resistance in Staphylococcus epidermidis colonizing veterinary staff and students". 2017.
  12. Frederico Holtreman; Sofia Santos Costa; Mafalda Rosa; Miguel Viveiros; Constança Pomba; Isabel Couto. "Characterization of plasmid encoded efflux determinants from Staphylococcus epidermidis". 2017.
  13. Cláudia Mineiro Santos; Sofia Santos Costa; Miguel Viveiros; Constança Pomba; Isabel Couto. "Prevalence of biofilm production in Staphylococcus epidermidis colonizing veterinary staff and students". 2017.
  14. Moisés Francisco; Sofia Santos Costa; Adriana Belas; Jorge Ramos; Isabel Couto; Constança Pomba; Miguel Viveiros. "Antimicrobial resistance and molecular characterization of Salmonella enterica serotype Typhi isolated in Luanda, Angola, in human specimens during 2013-2014". 2017.
  15. Isabel Couto; Sofia Santos Costa; Miguel Viveiros; Constança Pomba. "NorA mediated efflux in Staphylococcus epidermidis". 2017.
  16. Mafalda Rosa; Sofia Santos Costa; Miguel Viveiros; Constança Pomba; Isabel Couto. "Contribuição do efluxo para a resistência a compostos antimicrobianos em Staphylococcus epidermidis". 2017.
  17. Frederico Holtreman; Sofia Santos Costa; Mafalda Rosa; Miguel Viveiros; Constança Pomba; Isabel Couto. "Influência do efluxo na resistência a antibióticos e suscetibilidade reduzida aos biocidas em Staphylococcus epidermidis". 2017.
  18. Karen Mattos; Sofia Santos Costa; Isabel Couto; Carlos Emílio Levy; Cátia Marques; Patrícia Moriel; Constança Pomba; Miguel Viveiros. "Epidemiologia molecular e caracterização genética de estirpes de Klebsiella pneumoniae multirresistentes provenientes de um Hospital Universitário no Brasil". 2017.
  19. Cláudia Mineiro Santos; Sofia Santos Costa; Miguel Viveiros; Constança Pomba; Isabel Couto. "Correlação da produção de biofilme com a actividade de efluxo e resistência a antimicrobianos em Staphylococcus epidermidis". 2017.
  20. Sofia Santos Costa; Miguel Viveiros; Constança Pomba; Isabel Couto. "The role of efflux systems on antimicrobial resistance development in Staphylococcus epidermidis". 2017.
  21. Tommaso Felicetti; Rolando Cannalire; Giuseppe Manfroni; Oriana Tabarrini; Diana Machado; Isabel Couto; Sofia Santos Costa; et al. "Natural isoflavone biochanin-A as a template for the design of new and potent 3-phenylquinolone inhibitors of the nontuberculous mycobacteria efflux pumps". 2016.
  22. Sofia Santos Costa; Adriana Belas; Natacha Couto; Catarina Rodrigues; Miguel Viveiros; Constança Pomba; Isabel Couto. "Biocide susceptibility profiles of staphylococci colonizing humans in close contact with pets". 2015.
  23. Sofia Santos Costa; Miguel Viveiros; Josè Melo-Cristino; Isabel Couto. "The role of efflux in the development of multidrug resistance phenotypes in Staphylococcus aureus". 2014.
  24. Sofia Santos Costa; Miguel Viveiros; Josè Melo-Cristino; Isabel Couto. "Impact of active efflux in the development of MDR phenotypes in Staphylococcus aureus". 2014.
  25. Rita Branquinho; Salomé Moço; Sofia Santos Costa; Isabel Couto; Miguel Viveiros; Rodrigo Martins; Elvira Fortunato. "Low cost paper-based materials functionalized with nanoparticles for antibacterial applications". 2014.
  26. Sofia Santos Costa; Miguel Viveiros; Josè Melo-Cristino; Isabel Couto. "Efflux as a first-line response to fluoroquinolones and other antimicrobials in Staphylococcus aureus". 2013.
  27. Sofia Santos Costa; Miguel Viveiros; Josè Melo-Cristino; Isabel Couto. "Characterization of a multiresistance plasmid from a methicillin-resistant Staphylococcus aureus clinical strain". 2013.
  28. Cláudia Palma; Sofia Santos Costa; Miguel Viveiros; Josè Melo-Cristino; Isabel Couto. "The role of plasmid determinants in the resistance of Staphylococcus aureus to antimicrobial agents". 2013.
  29. Sofia Santos Costa; Miguel Viveiros; Isabel Couto. "Relevância clínica de sistemas de efluxo na resistência a compostos antimicrobianos em Staphylococcus aureus". 2012.
  30. Cláudia Mourato; Sofia Santos Costa; Miguel Viveiros; Leonard Amaral; Josè Melo-Cristino; Isabel Couto. "Co-resistance to biocides and beta-lactams in a MRSA clinical isolate". 2012.
  31. Sofia Santos Costa; Miguel Viveiros; Leonard Amaral; Patrick Butaye; Isabel Couto. "Susceptibility profiles of antibiotics, biocides and dyes in Staphylococcus aureus from pigs: correlation with efflux activity". 2012.
  32. Sofia Santos Costa; Miguel Viveiros; Leonard Amaral; Josè Melo-Cristino; Isabel Couto. "Efflux-mediated resistance to quaternary ammonium compounds in methicillin resistant Staphylococcus aureus (MRSA) clinical isolates". 2012.
  33. Sofia Santos Costa; Cláudia Mourato; Miguel Viveiros; Josè Melo-Cristino; Leonard Amaral; Isabel Couto. "Resistance to biocides conveyed by efflux pumps in clinical isolates of MRSA". 2012.
  34. Sofia Santos Costa; Miguel Viveiros; Leonard Amaral; Isabel Couto. "The role of NorA in the adaptative response of Staphylococcus aureus to stress stimuli". 2012.
  35. Sofia Santos Costa; Cláudia Mourato; Miguel Viveiros; Josè Melo-Cristino; Isabel Couto; Leonard Amaral. "Description of a novel staphylococcal pC194-family plasmid carrying the smr efflux pump gene". 2011.
  36. PINTO Antónia Rosa Trindade; Diana Machado; Sofia Santos Costa; Isabel Couto; Leonard Amaral; Miguel Viveiros. "Multidrug resistance mediated by active efflux in Escherichia coli". 2011.
  37. Cláudia Mourato; Sofia Santos Costa; Miguel Viveiros; Celeste Falcão; Josè Melo-Cristino; Leonard Amaral; Isabel Couto. "Multidrug resistance in a methicillin-resistant Staphylococcus aureus (MRSA) clinical isolate mediated by efflux pump QacA". 2011.
  38. Sofia Santos Costa; Cláudia Mourato; Miguel Viveiros; Josè Melo-Cristino; Isabel Couto; Leonard Amaral. "Description of a novel pC194-family plasmid carrying the smr efflux pump gene". 2011.
  39. Raúl Saraiva; Sofia Santos Costa; Isabel Couto; Miguel Viveiros; Maria José Feio; Paula Gameiro. "The role of enrofloxacin-based-metallocomplexes in the war against bacterial resistance". 2010.
  40. Sofia Santos Costa; Celeste Falcão; Miguel Viveiros; Diana Machado; MARTINS Marta Sofia Lopes; Josè Melo-Cristino; Leonard Amaral; Isabel Couto. "Importance of efflux systems on the resistance to fluoroquinolones by Staphylococcus aureus.". 2010.
  41. Sofia Santos Costa; Miguel Viveiros; Celeste Falcão; Josè Melo-Cristino; Leonard Amaral; Isabel Couto. "Genetic diversity of the Staphylococcus aureus efflux pump gene norA". 2010.
  42. Sofia Santos Costa; Celeste Falcão; Miguel Viveiros; Josè Melo-Cristino; Leonard Amaral; Isabel Couto. "Importance of efflux systems on the resistance to fluoroquinolones in Staphylococcus aureus". 2010.
  43. Celeste Falcão; Sofia Santos Costa; Miguel Viveiros; Diana Machado; MARTINS Marta Sofia Lopes; Josè Melo-Cristino; Leonard Amaral; Isabel Couto. "Importance of efflux systems on the resistance to fluoroquinolones by Staphylococcus aureus". 2009.
  44. MARTINS Marta Sofia Lopes; Miguel Viveiros; Isabel Couto; Sofia Santos Costa; Teresa Pacheco; Leonard Amaral. "New method for the rapid screening of efflux pump activity in multi-drug resistant clinical strains". 2009.
  45. Sofia Santos Costa; Isabel Couto; Miguel Viveiros; MARTINS Marta; Clara Leandro; Leonard Amaral. "Characterization of reduced susceptibility to biocides, dyes, and quinolones in a Staphylococcus aureus strain exposed to ethidium bromide". 2007.
  46. W.F. Canas Ferreira; A. Santos Pinto; A.P. Silva; E. Prieto; R. Albuquerque; C. Costa; F. Dias; et al. "Natural history of HIV-2 infection in an urban population from Guinea-Bissau: clinical and immunologic outcome, 1986-1992". 1993.
  47. João Piedade; Miguel Viveiros; C. Costa; A. Santos Pinto; E. Prieto; R. Albuquerque; L. Brum; et al. "Seroprevalence and risk factors associated with HIV infection in Guinea-Bissau". 1992.
  48. W.F. Canas Ferreira; A.P. Silva; E. Prieto; A.S. Pinto; R. Sousa; J. Monteiro; C. Costa; et al. "Natural history of HIV-2 infection in an urban population from Guinea- Bissau". 1992.
Resumo em conferência
  1. Diana Machado; Sarah Gothe; Marta Martins; Teresa Pacheco; Judite Batista; Cristina Toscano; Miguel Viveiros. "Colistin heteroresistance in carbapenemase-producing Acinetobacter baumannii". 2020.
  2. Diana Machado; Marco Pieroni; Miguel Viveiros. "Development of lipophilic efflux inhibitors as adjuvants of Mycobacterium tuberculosis chemotherapy". 2020.
  3. Thomas Schön; Erja Chryssanthou; H.Benmansour Florian Maurer; S. Boarbi; Petter Keller; Miguel Viveiros; Diana Machado; et al. "ECOFFs for non-tuberculous mycobacteria: towards a EUCAST reference method and clinical breakpoints for antimicrobial susceptibility testing". 2020.
  4. Diana Machado; Elisa Azzali; Isabel Couto; Gabriele Costantino; Marco Pieroni; Miguel Viveiros. "Targeting Mycobacterium tuberculosis with lipophilic efflux inhibitors exploring their dual activity: dissipation of the proton motive force and efflux inhibition". 2019.
  5. Jéssica Antunes; Diana Machado; Marta Martins; Isabel Couto; Teresa Pacheco; Judite Batista; Cristina Toscano; Miguel Viveiros. "Contribution of ß-lactamases, porins and efflux pumps to carbapenem resistance in Acinetobacter baumannii". 2019.
  6. Diana Machado; João Perdigão; Jorge Ramos; Ana Tavares; Abecasis AB; Sónia Dias; Taane G. Clark; et al. "Exploring the phenotypic and genetic basis of drug-resistant Mycobacterium tuberculosis strains in Lisbon, Portugal". 2019.
  7. Sarah Gothe; Diana Machado; Marta Martins; Teresa Pacheco; Judite Batista; Cristina Toscano; Miguel Viveiros. "Insights on Acinetobacter baumannii heteroresistance to colistin: what is the fate?". 2019.
  8. Miguel Viveiros; Diana Machado; Iolanda Neves; Marta Martins; Isabel Couto; Teresa Pacheco; Judite Batista; Cristina Toscano. "The contribution of membrane transporter proteins to extensively-drug resistant phenotypes in Acinetobacter baumannii". 2019.
  9. Thomas Schön; Miguel Viveiros; Jim Werngren; Daniella Cirrillo; Emanuele Borroni; Maria Wijkander; Diana Machado; et al. "Towards a new reference drug susceptibility testing method for Mycobacterium tuberculosis". 2019.
  10. Liliana Rodrigues; Pedro Cravo; Miguel Viveiros. "Chemogenomics and in silico repurposing as an innovative approach for rapid drug discovery in tuberculosis". 2019.
  11. Liliana Rodrigues; Pedro Cravo; Miguel Viveiros. "In silico repurposing of approved drugs against tuberculosis: targeting membrane transporters and energy metabolism". 2019.
  12. Diana Machado; João Perdigão; Jorge Ramos; Ana Tavares; Abecasis AB; Sónia Dias; Taane Clark; et al. "Epidemiologia molecular da resistência em Mycobacterium tuberculosis multirresistente em Lisboa". 2019.
  13. Denise O'Sullivan; Jody Phelan; Diana Machado; Miguel Viveiros; Taane G. Clark; Justin O'Grady; Jim F. Huggett. "Evaluation of the performance of MinION sequencing to identify multi- and extensively drug resistant tuberculosis". 2018.
  14. Diana Machado; Jéssica Antunes; Ana Simões; João Perdigão; Isabel Couto; Matthew P. McCusker; Marta Martins; et al. "Contribution of efflux to colistin heteroresistance in a multidrug resistant Acinetobacter baumannii clinical isolate". 2018.
  15. João Perdigão; Carla Silva; Jaciara Diniz; Catarina Pereira; Diana Machado; Jorge Ramos; Fernanda Silva; et al. "Genetic diversity and mapping of M. tuberculosis strains in Portuguese Speaking Countries". 2017.
  16. Jéssica Antunes; Diana Machado; Isabel Couto; Teresa Pacheco; Judite Batista; Cristina Toscano; Miguel Viveiros. "The contribution of efflux pumps and porins in Acinetobacter baumannii resistance to carbapenems". 2017.
  17. João Perdigão; Carla Silva; Jaciara Diniz; Catarina Pereira; Diana Machado; Jorge Ramos; Fernanda Silva; et al. "Tracking Mycobacterium tuberculosis across the seas: CPLP-TB and genetic diversity in the Lusophone space". 2017.
  18. João Perdigão; Sofia Clemente; Jorge Ramos; Pedro Masakidi; Diana Machado; Carla Silva; Isabel Couto; et al. "Genetic diversity, transmission dynamics and drug resistance of Mycobacterium tuberculosis in Luanda, Angola". 2017.
  19. A Armada; Bruno Costa Gomes; Jose Rueff; Miguel Viveiros; Antonio Sebastião Rodrigues. "Evaluation of the modulating effect of miR-203 and miR-200c on drug extrusion by ABCB1". 2017.
  20. Santos-Gomes, G; M. Rafael-Fernandes; A Armada; P. Ruas; J.H. Lago; F. Passero; Miguel Viveiros. "Eficácia da terapia combinada como estratégia alternativa ao tratamento convencional das leishmanioses.". 2017.
  21. Diana Machado; Faiza Mougari; Emmanuelle Cambau; Miguel Viveiros. "Genome downsizing and drug resistance in Mycobacterium leprae: are there places for drug efflux pumps?". 2016.
  22. A Armada; Bruno Costa Gomes; Jose Rueff; Antonio Sebastião Rodrigues; Miguel Viveiros. "MicroRNAs 203 e 200c regulam a expressão das bombas ABCB1 na resistência à doxorubicina". 2016.
  23. Cabral, V; Luo, X; Junqueira, E; Costa, S; Mulhovo, S; Duarte, A; Couto, I; Viveiros, M; Ferreira, MJU. "Zanthoxylum capense constituents and derivatives: Effects on the activity of antibiotics against Staphylococcus aureus strains". 2014.
    10.1055/s-0034-1395089
  24. Diana Machado; David Pires; João Perdigão; Jorge Ramos; Isabel Couto; Isabel Portugal; Elsa Anes; Miguel Viveiros. "Efflux inhibitors against drug resistant Mycobacterium tuberculosis: antimicrobial agents and enhancers of macrophage killing activity". 2014.
  25. Martins, C; Armada, A; Viveiros, M; Rueff, J; Rodrigues, AS. "Allylbenzenes as potential chemosensitizers and P-glycoprotein inhibitors". 2013.
  26. Diana Machado; Isabel Couto; Jorge Ramos; Miguel Viveiros. "Inibidores de efluxo como adjuvantes no tratamento da tuberculose resistente aos antibacilares". 2013.
  27. Diana Machado; Miguel Viveiros; Samuel Francisco; Jorge Ramos; Carlos Serra; Teresa Pacheco; Teresa Marques; et al. "Detecção directa de MDRTB em Portugal: métodos e aplicações comerciais. A experiência do IHMT". 2013.
  28. Pedro Pedrosa; Bruno Veigas; Diana Machado; João Perdigão; Isabel Portugal; Isabel Couto; Miguel Viveiros; P. V. Baptista. "Detecção de MDRTB por gold-nanoprobes – uma nova abordagem tecnológica desenvolvida em Portugal". 2013.
  29. Miguel Viveiros; Liliana Rodrigues; Diana Machado; Marta Martins; Isabel Couto; Leonard Amaral. "Significance of efflux in multidrug resistance in Mycobacterium tuberculosis". 2013.
  30. Paulo Rabna; Jorge Ramos; Gema Ponce; Fina Bamba; Diana Machado; A Armada; Lilica Sanca; et al. "Detecção directa da TB-MR através do teste Xpert MTB/RIF na Guiné-Bissau". 2013.
  31. Diana Machado; Isabel Couto; Jorge Ramos; Miguel Viveiros. "Anti-tuberculosis activity of efflux inhibitors against drug resistant Mycobacterium tuberculosis". 2013.
  32. Diana Machado; João Perdigão; Jorge Ramos; Isabel Couto; Isabel Portugal; Claudia Ritter; Erik C. Boettger; Miguel Viveiros. "High level resistance to isoniazid and ethionamide among multidrug resistant Mycobacterium tuberculosis strains from Lisbon, Portugal, is associated with double mutations in inhA gene". 2012.
  33. Diana Machado; João Perdigão; Jorge Ramos; Isabel Couto; Isabel Portugal; Claudia Ritter; Eric C. Boettger; Miguel Viveiros. "Resistência de alto nível à isoniazida e etionamida em estirpes de Mycobacterium tuberculosis multirresistentes está associada a mutações duplas no gene inhA". 2012.
  34. Miguel Viveiros; Diana Machado; Isabel Couto; João Perdigão; Isabel Portugal; Emmanuelle Cambau; Erik C. Boettger. "O teste de susceptibilidade semi-quantitativo de 1a e 2a linha para Mycobacterium tuberculosis usando o sistema BD EpiCenterTM TB-eXiST: um importante contributo para a Luta Contra a Tuberculose Resistente aos antibióticos". 2012.
  35. Sofia S. Costa; Celeste Falcão; Miguel Viveiros; Diana Machado; Miguel Martins; José Melo-Cristino; Leonard Amaral; Isabel Couto. "Importance of efflux systems on the resistance to fluoroquinolones in Staphylococcus aureus". 2010.
  36. Martins, A; Vasas, A; Schelz, Z; Martins, M; Viveiros, M; Molnar, J; Hohmann, J; Amoral, L. "Purification and identification of active compounds of Carpobrotus edulis against the reversal of resistance of human mdr1 gene transfected mouse lymphoma cells". 2008.
  37. Amaral, L; Spengler, G; Viveiros, M; Rodrigues, L; Martins, A; Couto, I; Martins, M; et al. "ASSESSMENT AND COMPARISON OF EFFLUX PUMPS OF CANCER CELLS AND MDR BACTERIA UNDER PHYSIOLOGICAL CONDITIONS BY A REAL-TIME SEMI-AUTOMATED SYSTEM". 2008.
  38. Spengler, G; Viveiros, M; Martins, A; Rodrigues, L; Martins, M; Molnar, J; Couto, I; Amaral, L. "DEMONSTRATION OF THE ACTIVITY OF P-GLYCOPROTEIN BY A FULLY AUTOMATED ETHIDIUM BROMIDE METHOD". 2008.
  39. Viveiros, M; Ordway, D; Hohmann, J; Leandro, C; Molnar, J; Amaral, L. "PLANT EXTRACT KILLS INTRACELLULAR MDR PATHOGENS, REVERSES MDR OF CANCER AND STEPS UP T CELL ACTIVITY". 2004.
  40. Amaral, L; Ordway, D; Viveiros, M; Martins, M; Leandro, C. "Thioridazine: evidence supporting its use as alternative therapy for MDR-TB". 2004.
  41. Amaral, L; Martins, M; Viveiros, M; Leandro, C; Ordway, D; Molnar, J. "VERAPAMIL AND RESERPIN PROMOTE THE KILLING OF INTRACELLULAR BACTERIA". 2004.
  42. João Piedade; Miguel Viveiros; C. Costa; A. Santos Pinto; E. Prieto; R. Albuquerque; A. Paulo Silva; et al. "HIV-2 seroprevalence in Guinea-Bissau". 1993.
Revisão de livro
  1. Amaral, Leonard; Viveiros, Miguel; Instituto de Higiene e Medicina Tropical (IHMT); Global Health and Tropical Medicine (GHTM); TB, HIV and opportunistic diseases and pathogens (THOP). "Thioridazine". http://www.scopus.com/inward/record.url?scp=85010430804&partnerID=8YFLogxK.
    https://doi.org/10.3390/antibiotics6010003
  2. Guerreiro, Cátia Sá; Hartz, Zulmira; Sambo, Luís; Conceição, Cláudia; Dussault, Gilles; Russo, Giuliano; Viveiros, Miguel; et al. "Scientific Research Policy for Health in Portugal: II - Facts and Suggestions". https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/8012.
  3. Sá Guerreiro, Cátia; Hartz, Zulmira; Sambo, Luís; Conceição, Cláudia; Dussault, Gilles; Russo, Giuliano; Viveiros, Miguel; et al. "Scientific Research Policy for Health in Portugal: I - European and National Environment". https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/8011.
  4. Rodrigues, Liliana; Cravo, Pedro; Viveiros, Miguel. "Efflux pump inhibitors as a promising adjunct therapy against drug resistant tuberculosis". http://hdl.handle.net/10362/105619.
    https://doi.org/10.1080/14787210.2020.1760845
Tese / Dissertação
  1. Ribeiro, José Francisco Valente. "Uma abordagem bioinformática para o estudo da contribuição das bombas de efluxo “Small Multidrug Resistance” na resistência aos antibióticos em Acinetobacter baumannii através da análise de genoma completo". Mestrado, 2020. http://hdl.handle.net/10362/93123.
  2. Serra, Débora Carvalho. "Detection and inhibition of ß-lactamase activity in clinical isolates of Escherichia coli combining ß-lactamase and efflux inhibitors using an MTT-based method: phenotypic and genotypic validation". Mestrado, 2020. http://hdl.handle.net/10362/97300.
  3. ARMADA, Ana Maria Buttle de Mendonça Mourão Possidónio de. "ABC efflux pumps in eukaryotic cells from function to regulation". Doutoramento, 2019. http://hdl.handle.net/10362/66659.
  4. FERREIRA, Mónica Eduarda Franco. "Diagnóstico e tratamento da infeção malárica: desenvolvimento de uma nova plataforma de diagnóstico e de um novo composto antimalárico". Mestrado, 2019. http://hdl.handle.net/10362/66269.
  5. TAVARES, Ana Maria Pinho. "HIV, tuberculosis and co-infection among migrant populations living in Portugal". Doutoramento, 2019. http://hdl.handle.net/10362/105852.
  6. COSTA, Ana Raquel Esteves. "Contribuição do efluxo para a emergência da resistência em bactérias persistentes". Mestrado, 2018. http://hdl.handle.net/10362/53496.
  7. FRANCISCO, Moisés. "Caracterização microbiológica e molecular das estirpes de Salmonella spp. isoladas em amostras clínicas, águas residuais e alimentos na região de Luanda e dos seus perfis de resistência aos antimicrobianos - o seu impacto na saúde pública.". Doutoramento, 2018. http://hdl.handle.net/10362/59484.
  8. THERON, Maria João de Resende. "Determinação da actividade de efluxo de Hoechst 33258 em Escherichia coli". Mestrado, 2018. http://hdl.handle.net/10362/66373.
  9. ANTUNES, Samuel Filipe Jesus. "Aplicação de um método fluorométrico em placa de 96 poços para a detecção de actividade de efluxo em bactérias". Mestrado, 2017. http://hdl.handle.net/10362/53802.
  10. GABRIEL, Marta Isabel Martins. "Resposta imunitária inflamatória de macrófagos na presença de inibidores de efluxo". Mestrado, 2016. http://hdl.handle.net/10362/19084.
  11. SIMÕES, Ana Sofia Mourão. "Contribuição do efluxo para a aquisição de resistência aos antibióticos em isolados clínicos de Acinetobacter baumannii". Mestrado, 2016. http://hdl.handle.net/10362/19196.
  12. EUSÉBIO, Ana Sofia Sancho. "Determinantes genéticos de virulência e de resistência aos antibióticos em isolados uropatogénicos de Escherichia coli provenientes da comunidade e do hospital.". Mestrado, 2015. http://hdl.handle.net/10362/19064.
  13. MACHADO, DIANA. "The dynamics of drug resistance in Mycobacterium tuberculosis: exploring the biological basis of multi- and extensively drug resistant tuberculosis (MDR/XDRTB) as a route for alternative therapeutic strategies". Doutoramento, 2014. http://hdl.handle.net/10362/20311.
  14. Chocalheiro, Ana Luísa Mateus. "Lab on paper: biossensores colorimétricos de papel para a detecção de membros do complexo Mycobacterium tuberculosis". Mestrado, 2014. http://hdl.handle.net/10362/13836.
  15. COSTA, Pedro Miguel Nisa. "Improved nucleic acid testing strategies to detect and discriminate veterinary relevant Mycobacterium tuberculosis complex members". Doutoramento, 2014. http://hdl.handle.net/10362/19272.
  16. PINTO, Antónia Rosa Trindade. "Resistência mediada por efluxo em Escherichia coli: novas estratégias terapêuticas utilizando antibióticos e inibidores do efluxo". Mestrado, 2012. http://hdl.handle.net/10362/14014.
  17. Cabral, Vanessa Roque. "Pesquisa de compostos com actividade inibidora de bombas de efluxo bacterianas". Mestrado, 2012. http://hdl.handle.net/10451/11231.
  18. RAMOS, Jorge Alexandre Santos. "Transporte do brometo de etídio através da parede celular de Mycrobacterium smegmatis: desenvolvimento e aplicação de metodologias de quantificação do transporte e correlação com a resistência aos antibióticos". Mestrado, 2010. http://hdl.handle.net/10362/10272.
  19. RODRIGUES, Liliana Isabel Dias; Rodrigues, Liliana. "The role of the efflux mechanisms in multidrug resistance in Mycobacterium tuberculosis". Doutoramento, 2010. http://hdl.handle.net/10362/4813.
  20. COSTA, Susana; COSTA, Susana Cristina Nunes Santos. "Caracterização preliminar da bioenergética do efluxo pelo sistema AcrAB-TolC EM Escherichia Coli". Mestrado, 2010. http://hdl.handle.net/10362/11410.
  21. MACHADO, Diana Oliveira. "Dinâmica fisiológica e mutacional da multirresistência em Mycobacterium tuberculosis". Mestrado, 2009. http://hdl.handle.net/10362/19211.
  22. CHAREPE, Nadia Borges. "Impacto da sobre-expressão de bombas de efluxo de estirpes E. coli MDR clínicas na resistência aos compostos antimicrobianos". Mestrado, 2008. http://hdl.handle.net/10362/19222.
  23. MARTINS, Marta Sofia Lopes. "The role played efflux systems on the resistance to antibiotics". Doutoramento, 2008. http://hdl.handle.net/10362/61898.
  24. MARTINS, Marta Sofia Lopes. "The antimycobacterial activity of thioridazine derivatives against drug resistant Mycobacterium tuberculosis: in vitro, ex vivo and in vivo studies". Doutoramento, 2008. http://hdl.handle.net/10362/61780.

Outros

Outra produção
  1. Pereira, Catarina; Gomes, Pedro; Taveira, Ricardo; Silva, Carla; Maltez, Fernando; Macedo, Rita; Costa, Catarina; et al. 2019. Insights on the Mycobacterium tuberculosis population structure associated with migrants from Portuguese-speaking countries over a three-year period in greater Lisbon, Portugal: Implications at the public health level. Tuberculosis among foreign-born patients is a key indicator of country-level epidemiological profiles and, of an increasing concern in Europe given the more intensified migratory waves of refugees. Since Portugal presents a lower immigrant-associated TB incidence rate when compared to other European countries, we sought to characterize the epidemiology and transmission dynamics among the foreign-b. http://hdl.handle.net/10400.18/6351.
    Infect Genet Evol. 2019 Jul;71:159-165. doi: 10.1016/j.meegid.2019.03.025. Epub 2019 Mar 27
  2. Perdigão, João; Silva, Carla; Diniz, Jaciara; Pereira, Catarina; Machado, Diana; Ramos, Jorge; Silva, Hugo; et al. 2019. CPLP-TB: a new tuberculosis transnational surveillance tool for the lusophone community. Tuberculosis (TB) remains a major health problem within the Community of Portuguese Language Speaking Countries (CPLP). Despite the marked variation in TB incidence across its member-states and continued human migratory flux between countries, a considerable gap in the knowledge on the Mycobacterium tuberculosis population structure and strain circulation between the countries still exists. To add. http://anaisihmt.com/index.php/ihmt/article/view/278.
  3. AM Tavares; AC Garcia; A Gama; AB Abecasis; Miguel Viveiros; Sónia Dias. 2019. Perceptions of primary care providers on TB care for migrants. a mixed methods study in Portugal. https://novaresearch.unl.pt/en/publications/0983da5a-3fbe-4caa-9b99-0fcabb18cfea.
  4. Viveiros, Miguel. 2018. O ENSINO DAS CIÊNCIAS MÉDICAS E BIOMÉDICAS NO INSTITUTO DE HIGIENE E MEDICINA TROPICAL – A CONTEXTUALIZAÇÃO HISTÓRICO-PEDAGÓGICO. .. http://anaisihmt.com/index.php/ihmt/article/view/233.
  5. Viveiros, Miguel; Matos, Olga. 2018. 4th National Congress of Tropical Medicine and 1st Lusophone Meeting on AIDS, Tuberculosis and Opportunistic Diseases. The Institute of Hygiene and Tropical Medicine in Lisbon (IHMT) and the Association for the Development of Tropical Medicine (ADMT) organized the 4th National Congress of Tropical Medicine (CNMT) on April 19-21, 2017 in Lisbon in tandem with the 1st Lusophone Meeting on AIDS, Tuberculosis and Opportunistic Diseases, integrating the 115th anniversary of the IHMT. This biennial event brought togethe. http://anaisihmt.com/index.php/ihmt/article/view/20.
  6. Viveiros, Miguel; Couto, Isabel. 2018. Brief history of mycobacteriology at IHMT/UNL. This article reviews the studies on tuberculosis and other mycobacterial diseases at the Institute of Hygiene and Tropical Medicine, over more than one hundred years of history of this institute. If in the first decades these studies were focused on the public care and support to the local health programs to control tuberculosis in all the countries and provinces where the institute was operating. http://anaisihmt.com/index.php/ihmt/article/view/168.
  7. Viveiros, Miguel; Simões, Maria João. 2018. Little history of RIDES-Tuberculosis in the Framework of the Strategic Plan 2009-2012 for cooperation in health of the Community of Portuguese Speaking Countries. Tuberculosis remains a major public health problem world-wide. In 2016, the WHO launched an appeal to governments, communities, civil society and the private sector to be "United to End Tuberculosis", promoting the dialogue and collaboration that unites people and communities to implement new ways to end the epidemic of tuberculosis (TB) and in particular of drug-resistant TB that continues to inc. http://anaisihmt.com/index.php/ihmt/article/view/104.
  8. Conceição, Cláudia; Viveiros, Miguel; Cruz, Deolinda; Rosado Pinto, José. 2018. 4th National Congress of Tropical Medicine - Chronic respiratory diseases and tuberculosis pre-congress seminar. On the 18th of April of 2017, the Institute of Tropical Medicine of the Nova University of Lisbon IHMT held the Pre-Congress Seminar, "Chronic respiratory diseases and tuberculosis". The seminar was organised comprising the following objectives: to increase the visibility and importance of chronic respiratory diseases in lusophone and international space; to provide opportunity of collaboration in. http://anaisihmt.com/index.php/ihmt/article/view/23.
  9. Castro, Rita; Costa, João; Couto, Isabel; Vieira, Maria Luísa; Viveiros, Miguel. 2018. INFEÇÕES BACTERIANAS NEGLIGENCIADAS, ESQUECIDAS OU DESCONHECIDAS? A TRADIÇÃO EXÓTICA DO IHMT. .. http://anaisihmt.com/index.php/ihmt/article/view/212.
  10. Machado, D; Girardini, M; Viveiros, M; Pieroni, M. 2018. Challenging the Drug-Likeness Dogma for New Drug Discovery in Tuberculosis.
    10.3389/fmicb.2018.01367
  11. Perdigão, João; Silva, Carla; Diniz, Jaciara; Pereira, Catarina; Machado, Diana; Ramos, Jorge; da Silva, Fernanda; et al. 2017. Tuberculosis across the seas: CPLP-TB - a joint effort in cataloguing mycobacterium tuberculosis genetic diversity in the lusophone space. The Community of Portuguese Language Speaking Countries (CPLP) comprises nine countries across four continents, accounting for 7.2% of the world’s land area, and where tuberculosis (TB) is still a cause of public health concern. A marked variation in TB incidence (23 to 551 cases per 100 000 habitants) can be observed across the different member-states and, despite of this, a considerable gap in t. http://hdl.handle.net/10400.18/4737.
  12. Perdigão, João; Clemente, Sofia; Ramos, Jorge; Masakidi, Pedro; Machado, Diana; Silva, Carla; Couto, Isabel; et al. 2017. Genetic diversity, transmission dynamics and drug resistance of Mycobacterium tuberculosis in Angola. Tuberculosis (TB) poses a serious public health problem in Angola. No surveillance data on drug resistance is available and nothing is known regarding the genetic diversity and population structure of circulating Mycobacterium tuberculosis strains. Here, we have genotyped and evaluated drug susceptibility of 89 Mycobacterium tuberculosis clinical isolates from Luanda. Thirty-three different spolig. http://hdl.handle.net/10362/24634.
    https://doi.org/10.1038/srep42814
  13. Coll, Francesc; McNerney, Ruth; Preston, Mark D.; Guerra-Assunção, José Afonso; Warry, Andrew; Hill-Cawthorne, Grant; Mallard, Kim; et al. 2015. Rapid determination of anti-tuberculosis drug resistance from whole-genome sequences. Mycobacterium tuberculosis drug resistance (DR) challenges effective tuberculosis disease control. Current molecular tests examine limited numbers of mutations, and although whole genome sequencing approaches could fully characterise DR, data complexity has restricted their clinical application. A library (1,325 mutations) predictive of DR for 15 anti-tuberculosis drugs was compiled and validated. http://hdl.handle.net/10400.18/3554.
    Genome Med. 2015 May 27;7(1):51. doi: 10.1186/s13073-015-0164-0. eCollection 2015.
  14. Isabel Couto; Miguel Viveiros; Leonard Amaral. 2010. Mutational and physiological dynamic of drug resistance in Mycobacterium tuberculosis, OP-8.. https://research.unl.pt/en/publications/mutational-and-physiological-dynamic-of-drug-resistance-in-mycobacterium-tuberculosis-op8(eb43570e-c273-4345-bc26-136e07324a6b).html.
  15. Leonard Amaral; Isabel Couto; Miguel Viveiros. 2010. Evaluation of the BD MGIT™ TBc identification test for the rapid detection of M. tuberculosis complex from cultures. https://unl.elsevierpure.com/en/publications/852fbf2f-fa8c-4bff-8437-fe74e987366c.
  16. Miguel Viveiros; Leonard Amaral. 2010. Biological activity of hydantoin derivatives on efflux pump systems of bacteria and cancer cells.. https://unl.elsevierpure.com/en/publications/db229c15-d116-4be6-87cb-ad33967082fc.
  17. Miguel Viveiros; Leonard Amaral; Isabel Couto. 2010. Importance of efflux systems on the resistance to fluoroquinolones in Staphylococcus aureus. (2). https://unl.elsevierpure.com/en/publications/4f8478bf-757e-4c53-a456-018cbfdf582d.
  18. Miguel Viveiros; Leonard Amaral; Isabel Couto. 2010. Contribution of efflux activity to isoniazid resistance in Mycobacterium tuberculosis complex. (1). https://unl.elsevierpure.com/en/publications/65337d27-8492-4b93-8155-243c494e5ef6.
  19. Miguel Viveiros. 2010. Contribution of the Mmr efflux pump to antimicrobial resistance in M. tuberculosis: construction of a mmr knockout mutant by allelic exchange.. https://unl.elsevierpure.com/en/publications/4b97f2f5-c873-4d86-a486-218440d194a6.
  20. Miguel Viveiros; António Grácio. 2010. Aedes (Stegomyia) aegypti (Diptera: Culicidae) in the Madeira Archipelago: bioecology.. https://unl.elsevierpure.com/en/publications/3033f072-c9f4-48f5-a3de-2b7b9372560d.
  21. Miguel Viveiros; Isabel Couto; Leonard Amaral. 2010. Genetic diversity of the Staphylococcus aureus efflux pump gene norA. (2). https://unl.elsevierpure.com/en/publications/4b3877fc-4c19-44f2-ad82-d149e83599c4.
  22. Miguel Viveiros; Leonard Amaral; Isabel Couto. 2010. Energetics, pH and intrinsic efflux pump systems of Gram-negative pathogens.. https://unl.elsevierpure.com/en/publications/5fb0d562-3b6e-468b-982c-7e974f991c86.
  23. Miguel Viveiros; Leonard Amaral; Isabel Couto. 2009. Mutational adaptation in Mycobacterium tuberculosis: the emergence of multidrug resistance.. https://research.unl.pt/en/publications/mutational-adaptation-in-mycobacterium-tuberculosis-the-emergence-of-multidrug-resistance(b4e15613-3b79-473a-acb6-22c39f38340e).html.
  24. Leonard Amaral; Isabel Couto; Miguel Viveiros. 2009. Early detection of MDRTB by molecular tools in the control of drug resistant tuberculosis in Portugal: a case of success.. https://research.unl.pt/en/publications/early-detection-of-mdrtb-by-molecular-tools-in-the-control-of-drug-resistant-tuberculosis-in-portugal-a-case-of-success(e1f38d60-5dd6-4572-ae45-7940ef9fd8b0).html.
  25. Miguel Viveiros; Leonard Amaral; Isabel Couto. 2009. New method for the rapid screening of efflux pump activity in multi-drug resistant clinical strains.. https://research.unl.pt/en/publications/new-method-for-the-rapid-screening-of-efflux-pump-activity-in-multidrug-resistant-clinical-strains(947c5a51-fef0-47c3-8472-ef1b133a3afc).html.
  26. Leonard Amaral; Miguel Viveiros; Isabel Couto. 2009. Contribution of efflux pump activity of macrolide resistance in M. avium complex.. https://research.unl.pt/en/publications/contribution-of-efflux-pump-activity-of-macrolide-resistance-in-m-avium-complex(a5a170e9-04ec-490b-b19c-6c6ea5b22cac).html.
  27. Miguel Viveiros; Leonard Amaral; Isabel Couto. 2009. The human macrophage as a model to select compounds active against MDR/XDR-TB.. https://unl.elsevierpure.com/en/publications/f375cc59-f45d-4a80-8e68-85a8f71ec4d5.
  28. Leonard Amaral; Isabel Couto; Miguel Viveiros. 2009. The role played by efflux pumps in macrolide resistance in Mycobacterium avium complex.. https://unl.elsevierpure.com/en/publications/217ce718-ee58-4a4e-b04e-3d76ac470e9d.
  29. Viveiros, M; Martins, M; Couto, I; Rodrigues, L; Spengler, G; Martins, A; Kristiansen, JE; Molnar, J; Amaral, L. 2008. New Methods for the Identification of Efflux Mediated MDR Bacteria, Genetic Assessment of Regulators and Efflux Pump Constituents, Characterization of Efflux Systems and Screening for Inhibitors of Efflux Pumps.
    10.2174/138945008785747734
  30. L Amaral; Diane Ordway; Miguel Viveiros; M Martins; C Leandro. 2004. Thioridazine. evidence supporting its use as alternative therapy for MDR-TB. https://novaresearch.unl.pt/en/publications/43b8add9-759a-49bb-804b-03160b0d6f52.
  31. Miguel Viveiros; Diane Ordway; Judit Hohmann; Clara Leandro; Joseph Molnar; Leonard Amaral. 2004. Plant extract kills intracellular MDR pathogens reverses MDR of cancer and steps up T cell activity. https://novaresearch.unl.pt/en/publications/f30b2adb-5f53-45ae-8f55-3379899dc8f5.
  32. Leonard Amaral; Miguel Viveiros; Peter Henderson. 2003. International Journal of Antimicrobial Agents. Foreword. https://research.unl.pt/en/publications/international-journal-of-antimicrobial-agents(97c60da8-d5c6-4202-9d3f-af694e7345c3).html.
    10.1016/s0924-8579(03)00223-1
Atividades

Orientação

Título / Tema
Papel desempenhado
Curso (Tipo)
Instituição / Organização
2020 - 2020 Uma abordagem bioinformática para o estudo da contribuição das bombas de efluxo “Small Multidrug Resistance” na resistência aos antibióticos em Acinetobacter baumannii através da análise de genoma completo
Orientador
Microbiologia Médica (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2018 - 2018 Contribuição do efluxo para a emergência da resistência em bactérias persistentes.
Orientador
Ciências Biomédicas (Mestrado)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2018 - 2018 Aplicação de um método fluorométrico em placa de 96 poços para a deteção de atividade de efluxo em bactérias.
Orientador
Ciências Biomédicas (Mestrado)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2016 - 2016 Resposta imunitária inflamatória de macrófagos na presença de inibidores de efluxo
Orientador
Ciências Biomédicas (Mestrado)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2016 - 2016 Contribuição do efluxo para a aquisição de resistência aos antibióticos em isolados clínicos de Acinetobacter baumannii.
Orientador
Microbiologia Médica (Mestrado)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2015 - 2015 ABC efflux pumps in eukaryotic cells From funtion to regulation
Orientador
Genética Humana e Doenças Infecciosas (Doutoramento)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2014 - 2014 Caracterização microbiológica e molecular das estirpes de Salmonella spp. isoladas em amostras de fezes, águas residuais e em ovos de produção aviárias na região de Luanda e dos seus perfis de resistência aos antimicrobianos - o seu impacto na saúde pública
Orientador
Ciências Biomédicas (Doutoramento)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2013 - 2013 Contribuição dos sistemas de efluxo na resistência à claritromicina no complexo Mycobacterium avium
Orientador
Ciências Biomédicas (Mestrado)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2010 - 2010 The dynamics of drug resistance in Mycobacterium tuberculosis: exploring the biological basis of multi - and multi extensively drug resistant tuberculosis (MDR/XDRTB) as a route for alternative therapeutic strategies
Orientador
Ciências Biomédicas (Doutoramento)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2005 - 2005 The Role of the Efflux Mechanisms in Multidrug Resistance in Mycobacterium Tuberculosis
Orientador
Ciências Biomédicas (Doutoramento)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal