| Artigo em conferência |
- Neves, Joana; Andrade, Mariana; Bento, Maria; Viveiros, Miguel; Rodrigues, Liliana; Couto, Isabel; Sofia Santos Costa; SS Costa; S Santos Costa. "Identification of new drugs targeting efflux and biofilms in Staphylococcus aureus and Staphylococcus epidermidis by an in silico drug repurposing approach". Trabalho apresentado em Webinar Frontiers in Cellular and Infection Microbiology para a coleção “Exploring Advanced Tools and Techniques for Studying Biofilms, 2024.
- Ferreira, Carolina; Abrantes, Patrícia; Costa, Sofia Santos; Viveiros, Miguel; Couto, Isabel. "Occurence and variability of norA and other main multidrug efflux pump determinants across the Staphylococcus genus". 2023.
- Rodrigues, Telma; Andrade, Mariana; Marques, Joana; Rodrigues, Liliana; Viveiros, Miguel; Silveira, Henrique; Couto, Isabel; Costa, Sofia Santos. "Implementation of a Galleria mellonella infection model at GHTM/IHMT-NOVA". 2023.
- Perdigão, João; Silva, Carla; Diniz, Jaciara; Pereira, Catarina; Machado, Diana; Ramos, Jorge; Silva, Hugo; et al. "Mycobacterium tuberculosis genetic diversity and drug resistance across Portuguese-speaking countries and CPLP-TB: a novel framework and surveillance tool for the Lusophone community". 2019.
- Sofia Santos Costa; Mafalda Rosa; Ana Catarina Rodrigues; Cláudia Mineiro Santos; Frederico Holtreman; Miguel Viveiros; Constança Pomba; Isabel Couto. "Emergence of non-wild-type populations towards biocides and antibiotic resistance in Staphylococcus epidermidis colonizing veterinary staff and students". 2018.
- Santos Costa, Sofia; Santos, Cláudia Mineiro; Viveiros, Miguel; Pomba, Constança. "Frequent biofilm production by Staphylococcus epidermidis causing infection in pets or colonizing veterinary staff". 2018.
- Santos Costa, Sofia; Rosato, Adriana E.; Viveiros, Miguel; Couto, Isabel. "Development of multidrug resistance in staphylococci driven by efflux". 2018.
- Santos Costa, Sofia; Rosa, Mafalda; Belas, Adriana; Viveiros, Miguel; Pomba, Constança; Couto, Isabel. "Biocide susceptibility in Staphylococcus epidermidis causing infection in pets". 2018.
- Costa, SS; Rosato, Adriana E.; Viveiros, M; Couto, I. "Development of multidrug resistance in staphylococci driven by efflux". 2018.
- Costa, SS; Kadlec, Kristina; Viveiros, M; Melo-Cristino, Josè; Schwarz, Stefan; Couto, I; Sofia Santos Costa; et al. "Complete sequences of two Staphylococcus aureus plasmids carrying genes for resistance to antibiotics, heavy-metals, biocides and/or virulence". 2018.
- Costa, SS; Rosa, Mafalda; Belas, Adriana; Viveiros, M; Pomba, Constança; Couto, I. "Biocide susceptibility in Staphylococcus epidermidis causing infection in pets". 2018.
- Costa, SS; Santos, Cláudia Mineiro; Viveiros, M; Pomba, Constança. "Frequent biofilm production by Staphylococcus epidermidis causing infection in pets or colonizing veterinary staff". 2018.
- Sofia Santos Costa; Mafalda Rosa; Ana Catarina Rodrigues; Frederico Holtreman; Miguel Viveiros; Constança Pomba; Isabel Couto. "Antibiotic and biocide resistance in Staphylococcus epidermidis colonizing humans in close contact with animals". 2017.
- Isabel Couto; Sofia Santos Costa; Diana Machado; Miguel Viveiros. "Microbial multiresistance in the era of global challenges – an urgent need for new approaches and technologies". 2017.
- Santos, Cláudia Mineiro; Costa, SS; Viveiros, Miguel; Pomba, Constança; Couto, I. "Prevalence of biofilm production in Staphylococcus epidermidis colonizing veterinary staff and students". 2017.
- Costa, SS; Rosa, Mafalda; Rodrigues, Ana Catarina; Holtreman, Frederico; Viveiros, Miguel; Pomba, Constança; Couto, I. "Antibiotic and biocide resistance in Staphylococcus epidermidis colonizing humans in close contact with animals". 2017.
- Holtreman, Frederico; Costa, SS; Rosa, Mafalda; Viveiros, Miguel; Pomba, Constança; Couto, I. "Characterization of plasmid encoded efflux determinants from Staphylococcus epidermidis". 2017.
- Costa, SS; Rosa, Mafalda; Rodrigues, Ana Catarina; Santos, Cláudia Mineiro; Holtreman, Frederico; Viveiros, Miguel; Pomba, Constança; Couto, I. "Characterization of antimicrobial resistance in Staphylococcus epidermidis colonizing veterinary staff and students". 2017.
- Costa, SS; Rosa, Mafalda; Rodrigues, Ana Catarina; Holtreman, Frederico; Viveiros, M; Pomba, Constança; Couto, I. "Antibiotic and biocide resistance in Staphylococcus epidermidis colonizing humans in close contact with animals". 2017.
- Costa, SS; Rosa, Mafalda; Rodrigues, Ana Catarina; Santos, Cláudia Mineiro; Holtreman, Frederico; Viveiros, M; Pomba, Constança; Couto, I. "Characterization of antimicrobial resistance in Staphylococcus epidermidis colonizing veterinary staff and students". 2017.
- Santos, Cláudia Mineiro; Costa, SS; Viveiros, M; Pomba, Constança; Couto, I. "Prevalence of biofilm production in Staphylococcus epidermidis colonizing veterinary staff and students". 2017.
- Holtreman, Frederico; Costa, SS; Rosa, Mafalda; Viveiros, M; Pomba, Constança; Couto, I. "Characterization of plasmid encoded efflux determinants from Staphylococcus epidermidis". 2017.
- Diana Machado; Elisa Azzali; Sofia Santos Costa; Gabriele Costantino; Isabel Couto; Marco Pieroni; Miguel Viveiros. "Antimycobacterial and efflux inhibitory activity of 2-aminothiazole lead compound against Mycobacterium tuberculosis". 2016.
- Elizeth Lopes; Sofia Santos Costa; Diana Machado; Marco Pieroni; Elisa Azzali; Gabriele Costantino; Miguel Viveiros; Isabel Couto. "Mycobacterium smegmatis model for the rapid screening of new compounds with efflux inhibitory and antimycobacterial activity". 2015.
- Perdigão, João; Clemente, Sofia; Ramos, Jorge; Masakidi, Pedro; Machado, Diana; Silva, Carla; Couto, Isabel; et al. "Drug resistance and genetic diversity of Mycobacterium tuberculosis in Luanda, Angola: a molecular epidemiological perspective". 2015.
- Perdigão, João; Clemente, Sofia; Ramos, Jorge; Masakidi, Pedro; Machado, Diana; Silva, Carla; Couto, Isabel; et al. "Drug resistance and genetic diversity of Mycobacterium tuberculosis in Luanda, Angola: a molecular epidemiological perspective". 2015.
- Sofia Santos Costa; Elisabete Junqueira; Cláudia Palma; Miguel Viveiros; Josè Melo-Cristino; Leonard Amaral; Isabel Couto. "Clinical relevance of efflux systems to antimicrobial resistance in Staphylococcus aureus". 2013.
- Leonard Amaral; Miguel Viveiros; Alexandru, T; Pascu, ML; Danko, B; Nastasa, V; Boni, M; et al. "Generation and biological evaluation of the pproducts formed from the exposure of phenothiazine to a 266 nm laser beam.". 2013.
10.1117/12.2032666
- Perdigão, João; Macedo, Rita; Machado, Diana; Silva, Carla; Jordão, Luísa; Couto, Isabel; Viveiros, Miguel; Portugal, Isabel. "Polymorphism in gidB gene as a genetic marker for the mycobacterium tuberculosis Q1 cluster and implications for the streptomycin resistance level". 2013.
- Perdigão, João; Macedo, Rita; Machado, Diana; Silva, Carla; Jordão, Luísa; Couto, Isabel; Viveiros, Miguel; Portugal, Isabel. "Polymorphism in gidB gene as a genetic marker for the mycobacterium tuberculosis Q1 cluster and implications for the streptomycin resistance level". 2013.
- Perdigao, joão; Macedo, Rita; Machado, Diana; Silva, Carla; Jordão, Luísa; Couto, Isabel; Viveiros, Miguel; Portugal, Isabel. "Correlation between streptomycin intermediate-level resistance and gidB mutation in an endemic multidrugresistant tuberculosis cluster". 2013.
- Perdigão, João; Silva, Hugo; Machado, Diana; Macedo, Rita; Maltez, Fernando; Silva, Carla; Jordão, Luísa; et al. "Genomic diversity of drug-resistant mycobacterium tuberculosis isolates in Lisbon Portugal: towards tuberculosis genomic epidemiology". 2013.
- Perdigao, Joao; Silva, D.; Pereira, V.; Macedo, Rita; Silva, Carla; Machado, Diana; Couto, Isabel; et al. "Dynamics and Development of Extensively Drug-resistant Tuberculosis, Portugal". 2012.
- Perdigao, Joao; Silva, D.; Pereira, V.; Macedo, Rita; Silva, Carla; Machado, Diana; Couto, Isabel; et al. "Dynamics and Development of Extensively Drug-resistant Tuberculosis, Portugal". 2012.
- Silva, Carla; Perdigão, João; Couto, Isabel; Viveiros, Miguel; Jordão, Luísa; Portugal, Isabel. "Deletion analysis on multidrug resistant Mycobacterium tuberculosis in Portugal". 2011.
- Silva, Carla; Perdigão, João; Couto, Isabel; Viveiros, Miguel; Jordão, Luísa; Portugal, Isabel. "Deletion analysis on multidrug resistant Mycobacterium tuberculosis in Portugal". 2011.
- Leonard Amaral; Gabriella Spengler; Liliana Rodrigues; Ana Martins; Marta Martins; Sofia Santos Costa; Isabel Couto; Miguel Viveiros. "Efflux pumps of bacteria and cancer cells". 2010.
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| Artigo em jornal |
- Pereira, Inês A.; André Pina; Beatriz Santos; Inês Vítor; Ana Henriques; João Fernandes; Filomena Pereira; et al. Autor correspondente: Liliana Rodrigues. "Targeting membrane transport and energy metabolism for the identification of new drugs for Neisseria gonorrhoeae using an in silico repurposing strategy", In the last stages of preparation to be submitted to Antibiotics (2025), 2025
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| Artigo em revista |
- Inês Pereira; André Pina; Inês Vítor; Beatriz Santos; Ana Henriques; Isabel Couto; Filomena M. Pereira; et al. "Targeting Membrane Transport and Energy Metabolism for the Identification of Repurposed Drug Candidates Against Neisseria gonorrhoeae Using an In Silico Strategy". Antibiotics (2026): https://doi.org/10.3390/antibiotics15060616.
10.3390/antibiotics15060616
- Gomes P; Paixão P; Maltez F; Brum L; Phelan J; Campino S; Clark T; et al. "The microevolutionary trajectory of endemic multidrug-resistant tuberculosis strains in Portugal toward increased drug resistance levels and its clinical significance". Frontiers in microbiology (2026): http://europepmc.org/abstract/PMC/PMC12868246.
- Pedro Gomes; Paulo Paixão; Fernando Maltez; Laura Brum; Jody E. Phelan; Susana Campino; Taane G. Clark; et al. "The microevolutionary trajectory of endemic multidrug-resistant tuberculosis strains in Portugal toward increased drug resistance levels and its clinical significance". Frontiers in Microbiology 16 (2026): https://novaresearch.unl.pt/en/publications/b83b96c2-46f7-42cc-a8d0-531f319493c0.
10.3389/fmicb.2025.1716549
- Andrade, Mariana; <; b> Neves, Joana< /b> ; Antunes, Carolina; Bento, Maria; Nunes, Matilde; Viveiros, Miguel; Rodrigues, Liliana; Couto, Isabel; Costa, Sofia S.. Autor correspondente: Costa, Sofia S.. "Targeting efflux and biofilms: screening of new candidate drugs for repurposing against antimicrobial-resistant <i>Staphylococcus aureus</i> and <i>Staphylococcus epidermidis</i>". To be submitted to Fronteirs in Pharmacology, special issue "Unravelling the Secrets of Multidrug Transport Proteins" (2026):
- Barreto H; Sousa JN; Ceballos NM; Leal M; Oliveira-Tintino CDM; Tintino SR; Coutinho HDM; et al. "Evaluation of new azole derivatives as potential antimicrobial agents or efflux inhibitors against <I>norA</i> overexpressing <i>Staphylococcus aureus</i>.". Bioorganic & Medicinal Chemistry (2026):
Submetido
- Maceiras AR; Silva ML; Couto J; Gonçalves R; Silva M; Macedo S; Machado D; et al. "Activation of nuclear receptors correlates with tuberculosis severity and is a target for host-directed therapy.". Frontiers in cellular and infection microbiology (2025): http://europepmc.org/abstract/med/41477004.
10.3389/fcimb.2025.1724798
- Pedro Eduardo Almeida da Silva; Andrea Von Groll; Ivy Bastos Ramis; Ana Julia Reis; Daniela Fernandes Ramos; Miguel Viveiros. "Efflux systems driving resistance and virulence across biological domains". PeerJ 13 (2025): https://peerj.com/articles/20360/.
10.7717/peerj.20360
- Drobniewski F; Ashmi M; Kusuma D; Ahmad R; Naumovas D; Juozapaite D; Toscano C; et al. "Determinants of vaccine hesitancy among healthcare workers in an international multicenter study within the EuCARE project.". Scientific reports (2025): http://europepmc.org/abstract/med/40877401.
10.1038/s41598-025-17507-y
- Mariana Andrade; Joana Neves; Maria Bento; Joana Marques; Sofia G. Seabra; Henrique Silveira; Liliana Rodrigues; et al. "Evaluation of Amlodipine and Imipramine Efficacy to Treat Galleria mellonella Infection by Biofilm-Producing and Antimicrobial-Resistant Staphylococcus aureus". Antibiotics (2025): https://doi.org/10.3390/antibiotics14020183.
10.3390/antibiotics14020183
- Elias R; Modesto A; Machado D; Pereira B; Phelan J; Melo-Cristino J; Lito L; et al. "Dissemination of arr-2 and arr-3 is associated with class 1 integrons in Klebsiella pneumoniae clinical isolates from Portugal.". Medical microbiology and immunology (2025): http://europepmc.org/abstract/med/39775075.
10.1007/s00430-024-00814-y
- Almeida da Silva P; Von Groll A; Ramis I; Reis A; Ramos D; Viveiros M. "Efflux systems driving resistance and virulence across biological domains". PeerJ (2025): http://europepmc.org/abstract/PMC/PMC12664331.
- Drobniewski F; Ashmi M; Kusuma D; Ahmad R; Naumovas D; Juozapaite D; Toscano C; et al. "Determinants of vaccine hesitancy among healthcare workers in an international multicenter study within the EuCARE project". Scientific reports (2025): http://europepmc.org/abstract/PMC/PMC12394626.
- Patil, Mrunal; Munteanu, T; Brasseur, G; Ferreira, Carolina; <B> Costa, Sofia Santos</B>; Couto, Isabel; Viveiros, Miguel; et al. Autor correspondente: Siri, O. "Unlocking the gates: a novel diagnostic molecule for quantifying efflux levels in Gram-positive bacteria". Submitted to Advanced Healthcare Materials (2025): https://doi.org/10.1002/adhm.202404145.
10.1002/adhm.202404145
- Marcela Bhering; Eunice Petris Ribeiro; Anna Karla Silveira; Carolyne Lalucha; Elizabete Oliveira Ribeiro; Tathiany Igreja; Luís Cristóvão Pôrto; et al. "Evaluation of T-NGS, Xpert Ultra, and Line Probe Assay on Clinical Samples for the Diagnosis of Drug-Resistant Pulmonary Tuberculosis in Rio de Janeiro". Revista da Sociedade Brasileira de Medicina Tropical (2025): https://doi.org/10.1590/0037-8682-0358-2025.
10.1590/0037-8682-0358-2025
- Oliveira Martins, Maria do Rosário; Viveiros, Miguel; Abrantes, Patrícia. "Teaching Quality at IHMT-NOVA: monitoring instruments for the period 2019 - 2024". (2025): https://doi.org/10.25761/anaisihmt.522.
https://doi.org/10.25761/anaisihmt.522
- Viveiros, Miguel; Ferreira, Albano; Gonçalves, Mauer; Fortes, Filomeno. "Biomedicine and Artificial Intelligence in Postgraduate Education in Health Sciences in Angola". (2025): https://doi.org/10.25761/anaisihmt.526.
https://doi.org/10.25761/anaisihmt.526
- Andrade, Mariana; <b>Neves, Joana</b>; Bento, Maria; Marques, Joana; Seabra, Sofia G.; Silveira, Henrique; Rodrigues , Liliana; et al. "Evaluation of Amlodipine and Imipramine Efficacy to Treat <i>Galleria mellonella</i> Infection by Biofilm-Producing and Antimicrobial-Resistant <i>Staphylococcus aureus</i>". Antibiotics 14 2 (2025): https://doi.org/10.3390/antibiotics14020183.
- Patil, Mrunal; Munteanu, Tatiana; Brasseur, Gaël; Ferreira, Carolina; Costa, Sofia Santos; Couto, Isabel; Athar, Mohd; et al. "Unlocking the Gates". (2025): http://hdl.handle.net/10362/182603.
https://doi.org/10.1002/adhm.202404145
- Wind Duarte Augusto; Joana Paula Mendes da Paixão; Miguel Viveiros; Santos de Morais Nicolau. "Sensitivity profile of pathogens identified in the diagnosis of urinary infection by uroculture carried out at the National Institute for Health Research, Luanda/Angola, during the pre - pandemic, intra - pandemic and post - pandemic of COVID 19". Brazilian Journal of Clinical Medicine and Review (2024): https://doi.org/10.52600/2965-0968.bjcmr.2024.2.4.3-14.
10.52600/2965-0968.bjcmr.2024.2.4.3-14
- Malaquias, Thiago da Silva Santos; Ribeiro, Eunice Petris; Dutra, Tatiana Cristina Pereira; Ricardo, Marina; Salvato, Richard; Bhering, Marcela; Bartholomeu, Daniella Castanheira; et al. "The performance of Xpert MTB/RIF and MTBDRplus within a Programmatic setting at TB Laboratory in Rio de Janeiro, Brazil". Revista da Sociedade Brasileira de Medicina Tropical (2024): https://www.scielo.br/j/rsbmt/a/bnK4998dCp4QZdksPJHkxwN/?lang=en.
https://doi.org/10.1590/0037-8682-0167-2024
- Francisco, Moisés; Belas, Adriana; Costa, Sofia Santos; Menezes, Juliana; Ramos, Jorge; Couto, Isabel; Viveiros, Miguel; et al. "Molecular Patterns and Antimicrobial Resistance Characterization of Salmonella enterica Non-Typhoidal from Human, Food, and Environment Samples Isolated in Luanda, Angola". Zoonotic Diseases (2024): http://hdl.handle.net/10362/179079.
https://doi.org/10.3390/zoonoticdis4040022
- Girardini, Miriam; Machado, Diana; Annunziato, Giannamaria; Papotti, Bianca; Palumbo, Marcella; Spaggiari, Chiara; Costantino, Gabriele; et al. "Preliminary structure-activity relationships analysis on N-(3,5-dichlorophenyl)-4,5-dihydronaphtho[1,2-d]thiazol-2-amine, a disruptor of mycobacterial energetics". Medicinal Chemistry Research 33 3 (2024): 518-531. https://link.springer.com/article/10.1007/s00044-024-03198-z.
https://doi.org/10.1007/s00044-024-03198-z
- Paulo Ferrinho; Miguel Viveiros; Inês Fronteira; Ferrinho, Paulo; Viveiros, Miguel; Fronteira, Inês. "Antimicrobial resistance, society and environment: A glocal syndemic". One Health (2023): https://app.dimensions.ai/details/publication/pub.1155483019.
10.1016/j.onehlt.2023.100512
- Fröberg G; Maurer FP; Chryssanthou E; Fernström L; Benmansour H; Boarbi S; Mengshoel AT; et al. "Towards clinical breakpoints for non-tuberculous mycobacteria - Determination of epidemiological cut off values for the Mycobacterium avium complex and Mycobacterium abscessus using broth microdilution.". Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases (2023): http://europepmc.org/abstract/med/36813087.
10.1016/j.cmi.2023.02.007
- Carolina Ferreira; Patrícia Abrantes; Sofia Santos Costa; Miguel Viveiros; Isabel Couto; Ferreira, Carolina; Abrantes, Patrícia; et al. "Occurrence and Variability of the Efflux Pump Gene norA across the Staphylococcus Genus". International Journal of Molecular Sciences (2022): https://doi.org/10.3390/ijms232315306.
10.3390/ijms232315306
- Kritski AL; Viveiros M; Carvalho ACC. "Rapid molecular diagnostics to detect resistance to second-line anti-TB drugs.". The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease (2022): http://europepmc.org/abstract/med/35505483.
10.5588/ijtld.22.0121
- Liliana Rodrigues; Renata Bento Cunha; Tatiana Vassilevskaia; Miguel Viveiros; Celso Cunha. "Drug Repurposing for COVID-19: A Review and a Novel Strategy to Identify New Targets and Potential Drug Candidates". Molecules (2022): https://doi.org/10.3390/molecules27092723.
10.3390/molecules27092723
- Antimycobacterial Susceptibility Testing Group; Antimycobacterial Susceptibility Testing Group:. "Updating the approaches to define susceptibility and resistance to anti-tuberculosis agents: implications for diagnosis and treatment.". The European respiratory journal (2022): http://europepmc.org/abstract/med/35422426.
10.1183/13993003.00166-2022
- Bateson A; Ortiz Canseco J; McHugh TD; Witney AA; Feuerriegel S; Merker M; Kohl TA; et al. "Ancient and recent differences in the intrinsic susceptibility of Mycobacterium tuberculosis complex to pretomanid.". The Journal of antimicrobial chemotherapy (2022): http://europepmc.org/abstract/med/35260883.
10.1093/jac/dkac070
- Marques, Joaquim Trigo; De Faria, Catarina Frazao; Reis, Marina; Machado, Diana; Santos, Susana; Santos, Maria da Soledade; Viveiros, Miguel; et al. "In vitro Evaluation of Isoniazid Derivatives as Potential Agents Against Drug-Resistant Tuberculosis". Frontiers in Pharmacology (2022): https://publons.com/publon/52849536/.
10.3389/FPHAR.2022.868545
- Rodrigues, Liliana; Cunha, Renata Bento; Vassilevskaia, Tatiana; Viveiros, Miguel; Cunha, Celso. "Drug Repurposing for COVID-19". (2022): http://hdl.handle.net/10362/140465.
https://doi.org/10.3390/molecules27092723
- Deisy M. G. C. Rocha; Miguel Viveiros; Margarida Saraiva; Nuno S. Osório; Rocha, Deisy M.G.C.; Viveiros, Miguel; Saraiva, Margarida; Osório, Nuno S.. "The Neglected Contribution of Streptomycin to the Tuberculosis Drug Resistance Problem". Genes (2021): https://doi.org/10.3390/genes12122003.
10.3390/genes12122003
- Catarina Frazão de Faria; Tânia Moreira; Pedro Lopes; Henrique Costa; Jessica R. Krewall; Callie M. Barton; Susana Santos; et al. "Designing new antitubercular isoniazid derivatives with improved reactivity and membrane trafficking abilities". Biomedicine and Pharmacotherapy 144 (2021): 1-9. https://www.sciencedirect.com/science/article/pii/S075333222101146X.
10.1016/j.biopha.2021.112362
- Jaciara de Lourdes do Carmo Guimarães Diniz; Andrea von Groll; Gisela Unis; Elis Regina Dalla-Costa; Maria Lúcia Rosa Rossetti; Júlia Silveira Vianna; Daniela Fernandes Ramos; et al. "Whole-genome sequencing as a tool for studying the microevolution of drug-resistant serial Mycobacterium tuberculosis isolates". Tuberculosis 131 (2021): 1-9. https://www.sciencedirect.com/science/article/pii/S1472979221000871.
10.1016/j.tube.2021.102137
- Ortiz M; Jauset-Rubio M; Skouridou V; Machado D; Viveiros M; Clark TG; Simonova A; et al. "Electrochemical Detection of Single-Nucleotide Polymorphism Associated with Rifampicin Resistance in <i>Mycobacterium tuberculosis</i> Using Solid-Phase Primer Elongation with Ferrocene-Linked Redox-Labeled Nucleotides.". ACS sensors (2021): http://europepmc.org/abstract/med/34797987.
10.1021/acssensors.1c01710
- Gómez-González PJ; Perdigao J; Gomes P; Puyen ZM; Santos-Lazaro D; Napier G; Hibberd ML; et al. "Genetic diversity of candidate loci linked to Mycobacterium tuberculosis resistance to bedaquiline, delamanid and pretomanid.". Scientific reports (2021): http://europepmc.org/abstract/med/34593898.
10.1038/s41598-021-98862-4
- Salvato RS; Reis AJ; Schiefelbein SH; Gómez MAA; Salvato SS; da Silva LV; Costa ERD; et al. "Genomic-based surveillance reveals high ongoing transmission of multidrug-resistant Mycobacterium tuberculosis in Southern Brazil.". International journal of antimicrobial agents (2021): http://europepmc.org/abstract/med/34289403.
10.1016/j.ijantimicag.2021.106401
- Rodrigues L; Aínsa JA; Viveiros M; Rodrigues, L.; Viveiros, M.; Aínsa, J.A.. "Measuring Efflux and Permeability in Mycobacteria.". Methods in molecular biology (Clifton, N.J.) 1285 (2021): http://europepmc.org/abstract/med/34235655.
10.1007/978-1-0716-1460-0_9
- Viveiros, Miguel. "Editorial: Tuberculosis and Non-tuberculous Mycobacteria Infections: Control, Diagnosis and Treatment". (2021): https://publons.com/publon/50452611/.
10.3389/fpubh.2021.666187
- Ortiz, Mayreli; Jauset-Rubio, Miriam; Skouridou, Vasso; Machado, Diana; Viveiros, Miguel; Clark, Taane G.; Simonova, Anna; et al. "Electrochemical Detection of Single-Nucleotide Polymorphism Associated with Rifampicin Resistance in Mycobacterium tuberculosis Using Solid-Phase Primer Elongation with Ferrocene-Linked Redox-Labeled Nucleotides". (2021): http://hdl.handle.net/10362/130385.
https://doi.org/10.1021/acssensors.1c01710
- Gómez-González, Paula J.; Perdigao, Joao; Gomes, Pedro; Puyen, Zully M.; Santos-Lazaro, David; Napier, Gary; Hibberd, Martin L.; et al. "Genetic diversity of candidate loci linked to Mycobacterium tuberculosis resistance to bedaquiline, delamanid and pretomanid". (2021): http://hdl.handle.net/10362/127473.
https://doi.org/10.1038/s41598-021-98862-4
- Salvato, Richard Steiner; Reis, Ana Júlia; Schiefelbein, Sun Hee; Gómez, Michael Andrés Abril; Salvato, Stéphanie Steiner; da Silva, Larissa Vitória; Costa, Elis Regina Dalla; et al. "Genomic-based surveillance reveals high ongoing transmission of multi-drug-resistant Mycobacterium tuberculosis in Southern Brazil". (2021): http://hdl.handle.net/10362/133338.
https://doi.org/10.1016/j.ijantimicag.2021.106401
- Schön, Thomas; Werngren, Jim; Machado, Diana; Borroni, Emanuele; Wijkander, Maria; Lina, Gerard; Mouton, Johan; et al. "Multicentre testing of the EUCAST broth microdilution reference method for MIC determination on Mycobacterium tuberculosis". Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases (2021): http://hdl.handle.net/10362/116505.
https://doi.org/10.1016/j.cmi.2020.10.019
- Tatiana Tozar; Sofia Santos Costa; Ana Maria Udrea; Viorel Nastasa; Isabel Couto; Miguel Viveiros; Mihail Lucian Pascu; et al. "Anti-staphylococcal activity and mode of action of thioridazine photoproducts". Scientific Reports Vol. 10 n.º 1 (2020): 18043-18055. https://novaresearch.unl.pt/en/publications/7f6bf3c7-512d-4cc3-b0e3-b9942d360c3a.
10.1038/s41598-020-74752-z
- Viveiros, Miguel; Perdigão, João; Gomes, Pedro; Miranda, Anabela; Maltez, Fernando; Machado, Diana; Silva, Carla; et al. "Using genomics to understand the origin and dispersion of multidrug and extensively drug resistant tuberculosis in Portugal". Scientific Reports (2020): http://dx.doi.org/10.1038/s41598-020-59558-3.
10.1038/s41598-020-59558-3
- João Perdigão; Carla Quintão; Fernando Maltez; Diana Machado; Anabela Miranda; Isabel Couto; Paulo Rabna; et al. "Emergence of multidrug-resistant Mycobacterium tuberculosis of the Beijing lineage in Portugal and Guinea-Bissau: a snapshot of moving clones by whole-genome sequencing". Emerging microbes & infections Vol. 9 n.º 1 (2020): 1342-1353. https://novaresearch.unl.pt/en/publications/997d4a3c-12af-4798-9249-b96d29a2d325.
10.1080/22221751.2020.1774425
- Verza M; Scheffer MC; Salvato RS; Schorner MA; Barazzetti FH; de Melo Machado H; Medeiros TF; et al. "Author Correction: Genomic epidemiology of Mycobacterium tuberculosis in Santa Catarina, Southern Brazil.". Scientific reports (2020): http://europepmc.org/abstract/med/33139782.
10.1038/s41598-020-76386-7
- Tavares A; Pingarilho M; Batista J; Viveiros M; Dias S; Toscano C; Gomes P; Abecasis AB. "HIV and tuberculosis co-infection among migrants in Portugal: a brief study on their sociodemographic, clinical, and genomic characteristics.". AIDS research and human retroviruses (2020): http://europepmc.org/abstract/med/32962419.
10.1089/aid.2020.0119
- Thomas Schön; Jim Werngren; Diana Machado; Emanuele Borroni; Maria Wijkander; Gerard Lina; Johan Mouton; et al. "Antimicrobial susceptibility testing of Mycobacterium tuberculosis complex isolates". Clin. Microbiol. Infect Supl. 1198 n.º 20 (2020): 30444-30465. https://novaresearch.unl.pt/en/publications/6058800c-bdc4-464b-9cba-9edb82ab1942.
10.1016/j.cmi.2020.07.036.
- Schön T; Köser CU; Werngren J; Viveiros M; Georghiou S; Kahlmeter G; Giske C; et al. "What is the role of the EUCAST reference method for MIC testing of the Mycobacterium tuberculosis complex?". Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases (2020): http://europepmc.org/abstract/med/32768492.
10.1016/j.cmi.2020.07.037
- Min Ong CW; Migliori GB; Raviglione M; MacGregor-Skinner G; Sotgiu G; Alffenaar JW; Tiberi S; et al. "Epidemic and pandemic viral infections: impact on tuberculosis and the lung. A consensus by the World Association for Infectious Diseases and Immunological Disorders (WAidid), Global Tuberculosis Network (GTN) and members# of ESCMID Study Group for Mycobacterial Infections (ESGMYC).". The European respiratory journal (2020): http://europepmc.org/abstract/med/32586885.
10.1183/13993003.01727-2020
- Verza M; Scheffer MC; Salvato RS; Schorner MA; Barazzetti FH; Machado HM; Medeiros TF; et al. "Genomic epidemiology of Mycobacterium tuberculosis in Santa Catarina, Southern Brazil.". Scientific reports (2020): http://europepmc.org/abstract/med/32732910.
10.1038/s41598-020-69755-9
- Liliana Rodrigues; Pedro Cravo; Miguel Viveiros; Rodrigues, Liliana; Cravo, Pedro; Viveiros, Miguel. "Efflux pump inhibitors as a promising adjunct therapy against drug resistant tuberculosis: a new strategy to revisit mycobacterial targets and repurpose old drugs". Expert Review of Anti-infective Therapy (2020): https://doi.org/10.1080/14787210.2020.1760845.
10.1080/14787210.2020.1760845
- Richard Steiner Salvato; Elis Regina Dalla Costa; Ana Júlia Reis; Sun Hee Schiefelbein; Maria Laura Halon; Regina Bones Barcellos; Gisela Unis; et al. "First insights into circulating XDR and pre-XDR Mycobacterium tuberculosis in Southern Brazil". Infection, Genetics and Evolution 78 (2020): 104127-104127. https://doi.org/10.1016/j.meegid.2019.104127.
10.1016/j.meegid.2019.104127
- Neves CP; Costa AG; Safe IP; de Souza Brito A; Jesus JS; Kritski AL; Lacerda MVG; Viveiros M; Cordeiro-Santos M. "The role of mini-bronchoalveolar lavage fluid in the diagnosis of pulmonary tuberculosis in critically ill patients.". BMC Infectious Diseases (2020): http://europepmc.org/abstract/med/32188399.
10.1186/s12879-020-04954-3
- Borsoi AF; Paz JD; Abbadi BL; Macchi FS; Sperotto N; Pissinate K; Rambo RS; et al. "Design, synthesis, and evaluation of new 2-(quinoline-4-yloxy)acetamide-based antituberculosis agents.". European journal of medicinal chemistry (2020): http://europepmc.org/abstract/med/32113048.
10.1016/j.ejmech.2020.112179
- Méchaï F; Cordel H; Guglielmetti L; Aubry A; Jankovic M; Viveiros M; Santin M; et al. "Management of Tuberculosis: Are the Practices Homogeneous in High-Income Countries?". Frontiers in public health 8 (2020): http://europepmc.org/abstract/PMC/PMC7509453.
10.3389/fpubh.2020.00443
- Silvana Miranda; Isabela Almeida; Maria Mansur; Lida Figueredo; Wânia Carvalho; João Hadaad; Jaciara Diniz; et al. "Detection of drug resistant Mycobacterium tuberculosis strains using Kit SIRE Nitratase". Brazilian Archives of Biology and Technology Vol. 63 (2020): e20190179-e20190188. https://novaresearch.unl.pt/en/publications/4fc5a85d-c2bb-48da-9b8d-9da720ec66a6.
https://doi.org/10.1590/1678-4324-2020190179
- Silvana Spindola de Miranda; Isabela Neves de Almeida; Maria de Fátima Filardi Oliveira Mansur; Lida Jouca de Assis Figueredo; Wânia da Silva Carvalho; João Paulo Amaral Hadaad; Jaciara de Lourdes do Carmo Guimarães Diniz; et al. "Detection of drug resistant mycobacterium tuberculosis strains using kit SIRE nitratase®". Brazilian Archives Of Biology And Technology 63 (2020): 1-9. https://novaresearch.unl.pt/en/publications/04f7768b-3da4-43d5-8514-9a45c7059216.
10.1590/1678-4324-2020190179
- Gomes, Bruno C.; Honrado, Mónica; Armada, Ana; Viveiros, Miguel; Rueff, José; Rodrigues, António S.; Bruno C. Gomes; et al. "ABC Efflux Transporters and the Circuitry of miRNAs". International Journal of Molecular Sciences (2020): http://hdl.handle.net/10362/97345.
10.3390/ijms21082985Scopus
- Santos, Tânia Raquel Martins dos Martins dos. "Novel Therapeutic Strategies for the Management of Diabetic Foot Infections : the Evaluation of Selected Antimicrobial Peptides Against Clinically Isolated Bacterial Pathogens". Universidade de Lisboa (Portugal) (2020): https://publons.com/wos-op/publon/64843842/.
- Verza, Mirela; Scheffer, Mara Cristina; Salvato, Richard Steiner; Schorner, Marcos André; Barazzetti, Fernando Hartmann; Machado, Hanalydia de Melo; Medeiros, Taiane Freitas; et al. "Genomic epidemiology of Mycobacterium tuberculosis in Santa Catarina, Southern Brazil". (2020): http://hdl.handle.net/10362/116602.
https://doi.org/10.1038/s41598-020-69755-9
- Miranda,Silvana Spindola de; Almeida,Isabela Neves de; Mansur,Maria de Fátima Filardi Oliveira; Figueredo,Lida Jouca de Assis; Carvalho,Wânia da Silva; Hadaad,João Paulo Amaral; Diniz,Jaciara de Lourdes do Carmo Guimarães; et al. "Detection of Drug Resistant Mycobacterium Tuberculosis Strains Using Kit SIRE Nitratase®: a Multicenter Study". (2020): http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132020000100308.
- Vieira ML; Liliana Rodrigues; Fernando Almeida; Filomeno Fortes; Sousa, Germano de; Monteiro, Sandra; Henrique Silveira; Miguel Viveiros. "O contributo dos serviços de diagnóstico laboratorial para o acesso universal à saúde nos países da Comunidade de Língua Portuguesa". Anais do Instituto de Higiene e Medicina Tropical Vol. 18 (2019): 42-51. https://novaresearch.unl.pt/en/publications/1b0e72c7-7520-4e49-a756-9d825609d611.
https://doi.org/10.25761/anaisihmt.337
- Peter Brown; Aik-Choon Tan; Mohamed A. El-Esawi; Thomas Liehr; Oliver Blanck; Douglas P. Gladue; Gabriel M. F. Almeida; et al. "Large expert-curated database for benchmarking document similarity detection in biomedical literature search". DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION Vol. 2019 (2019): 1-66. https://novaresearch.unl.pt/en/publications/9a3d235f-7197-4ca3-b449-12d8b73c663e.
10.1093/database/baz085
- Júlia S. Vianna; Diana Machado; Ivy B. Ramis; Fábia P. Silva; Dienefer V. Bierhals; Michael Andrés Abril; Andrea von Groll; et al. "The Contribution of Efflux Pumps in Mycobacterium abscessus Complex Resistance to Clarithromycin". Antibiotics (2019): https://doi.org/10.3390/antibiotics8030153.
10.3390/antibiotics8030153
- Cá B; Fonseca KL; Sousa J; Maceiras AR; Machado D; Sanca L; Rabna P; et al. "Experimental Evidence for Limited in vivo Virulence of Mycobacterium africanum.". Frontiers in microbiology (2019): http://europepmc.org/abstract/med/31552007.
10.3389/fmicb.2019.02102
- Tatara MB; Perdigão J; Viveiros M; Kritski A; Esther da Silva K; Correia Sacchi FP; Camioli de Lima C; Pereira Dos Santos PC; Andrade MKN. "Genetic Diversity and Molecular Epidemiology of Mycobacterium tuberculosis in Roraima State, Brazil.". The American journal of tropical medicine and hygiene (2019): http://europepmc.org/abstract/med/31392954.
10.4269/ajtmh.19-0324
- Pena E; Machado D; Viveiros M; Jordão S. "A case report of disseminated Mycobacterium colombiense infection in an HIV patient.". International journal of mycobacteriology (2019): http://europepmc.org/abstract/med/31512608.
10.4103/ijmy.ijmy_100_19
- Phelan JE; O'Sullivan DM; Machado D; Ramos J; Oppong YEA; Campino S; O'Grady J; et al. "Integrating informatics tools and portable sequencing technology for rapid detection of resistance to anti-tuberculous drugs.". Genome medicine (2019): http://europepmc.org/abstract/med/31234910.
10.1186/s13073-019-0650-x
- Irene Rossi; Francesca Buttini; Fabio Sonvico; Filippo Affaticati; Francesco Martinelli; Giannamaria Annunziato; Diana Machado; et al. "Sodium Hyaluronate Nanocomposite Respirable Microparticles to Tackle Antibiotic Resistance with Potential Application in Treatment of Mycobacterial Pulmonary Infections". Pharmaceutics (2019): https://doi.org/10.3390/pharmaceutics11050203.
10.3390/pharmaceutics11050203
- Tavares AM; Garcia AC; Gama A; Abecasis AB; Viveiros M; Dias S. "Tuberculosis care for migrant patients in Portugal: a mixed methods study with primary healthcare providers.". BMC health services research (2019): http://europepmc.org/abstract/med/30999913.
10.1186/s12913-019-4050-0
- Felicetti T; Machado D; Cannalire R; Astolfi A; Massari S; Tabarrini O; Manfroni G; et al. "Modifications on C6 and C7 positions of 3-phenylquinolone efflux pump inhibitors led to potent and safe anti-mycobacterial treatment adjuvants.". ACS infectious diseases (2019): http://europepmc.org/abstract/med/30907573.
10.1021/acsinfecdis.9b00041
- Catarina Pereira; Pedro Gomes; Ricardo Taveira; Carla Silva; Fernando Maltez; Rita Macedo; Catarina Costa; et al. "Insights on the Mycobacterium tuberculosis population structure associated with migrants from Portuguese-speaking countries over a three-year period in greater Lisbon, Portugal: Implications at the public health level". Infection, Genetics and Evolution (2019): https://doi.org/10.1016/j.meegid.2019.03.025.
10.1016/j.meegid.2019.03.025
- Oppong YEA; Phelan J; Perdigão J; Machado D; Miranda A; Portugal I; Viveiros M; Clark TG; Hibberd ML. "Genome-wide analysis of Mycobacterium tuberculosis polymorphisms reveals lineage-specific associations with drug resistance.". BMC genomics (2019): http://europepmc.org/abstract/med/30922221.
10.1186/s12864-019-5615-3
- Bouceiro-Mendes R; Ortins-Pina A; Fraga A; Marques T; Viveiros M; Machado D; Soares-de-Almeida L; Freitas JP; Filipe P. "Mycobacterium marinum lymphocutaneous infection.". Dermatology online journal (2019): http://europepmc.org/abstract/med/30865411.
- Júlia S. Vianna; Ivy B. Ramis; Dienefer Bierhals; Andrea von Groll; Daniela F. Ramos; Nilo Zanatta; Maria Cristina Lourenço; Miguel Viveiros; Pedro E.Almeida da Silva. "Tetrahydropyridine derivative as efflux inhibitor in Mycobacterium abscessus". Journal of Global Antimicrobial Resistance (2019): https://doi.org/10.1016/j.jgar.2018.12.020.
10.1016/j.jgar.2018.12.020
- Ramis, I.B.; Vianna, J.S.; Silva Junior, L.; von Groll, A.; Ramos, D.F.; Zanatta, N.; Viveiros, M.; Silva, P.E.A.D.. "In silico and in vitro evaluation of tetrahydropyridine compounds as efflux inhibitors in Mycobacterium abscessus". Tuberculosis 118 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85069975225&partnerID=MN8TOARS.
10.1016/j.tube.2019.07.004
- Viveiros, Miguel; Armada, Ana; Gomes, Bruno Costa; Viveiros, Miguel; Rueff, José; Rodrigues, António Sebastião; Instituto de Higiene e Medicina Tropical (IHMT); et al. "Regulation of ABCB1 activity by microRNA-200c and microRNA-203a in breast cancer cells: the quest for microRNAs’ involvement in cancer drug resistance". Cancer Drug Resistance (2019): http://dx.doi.org/10.20517/cdr.2019.24.
10.20517/cdr.2019.24
- Vieira, Marisa Luísa; Rodrigues, Liliana; Almeida, Fernando; Fortes, Filomeno; de Sousa, Germano; Monteiro, Sandra; Silveira, Henrique; Viveiros, Miguel. "Laboratory services contribution to supporting public health and health services in Portuguese-speaking countries". (2019): http://anaisihmt.com/index.php/ihmt/article/view/337.
- R. Bouceiro-Mendes; A. Ortins-Pina; T. Marques; Miguel Viveiros; Diana Machado; L. Lito; J. Ferreira; et al. "A case report of multibacillary leprosy presenting with multiple outbreaks of erythema nodosum leprosum". Journal of the Portuguese Society of Dermatology and Venereology 77 1 (2019): 67–72-67–72. https://novaresearch.unl.pt/en/publications/8a92e91f-1688-481c-99d7-06cd5bea0d22.
- Vianna, Júlia S.; Machado, Diana; Ramis, Ivy B.; Silva, Fábia P.; Bierhals, Dienefer V.; Abril, Michael Andrés; Groll, Andrea von; et al. "The Contribution of efflux pumps in Mycobacterium abscessus complex resistance to clarithromycin". (2019): https://www.arca.fiocruz.br/handle/icict/36952.
10.3390/antibiotics8030153
- Phelan, Jody E.; O'Sullivan, Denise M.; Machado, Diana; Ramos, Jorge; Oppong, Yaa E.A.; Campino, Susana; O'Grady, Justin; et al. "Integrating informatics tools and portable sequencing technology for rapid detection of resistance to anti-tuberculous drugs". (2019): http://hdl.handle.net/10362/116711.
https://doi.org/10.1186/s13073-019-0650-x
- Santos Costa, Sofia; Sobkowiak, Benjamin; Parreira, Ricardo; Edgeworth, Jonathan D.; Viveiros, Miguel; Clark, Taane G.; Couto, Isabel; et al. "Genetic Diversity of norA, Coding for a Main Efflux Pump of Staphylococcus aureus". Frontiers in Genetics 9 (2019): http://hdl.handle.net/10362/116697.
https://doi.org/10.3389/fgene.2018.00710
- Tavares, Ana Maria; Garcia, Ana Cristina; Gama, Ana; Abecasis, Ana B; Viveiros, Miguel; Dias, Sónia. "Tuberculosis care for migrant patients in Portugal". (2019): http://hdl.handle.net/10362/116708.
https://doi.org/10.1186/s12913-019-4050-0
- Oppong, Yaa E. A.; Phelan, Jody; Perdigao, Joao; Machado, Diana; Miranda, Anabela; Portugal, Isabel; Viveiros, Miguel; Clark, Taane G.; Hibberd, Martin L.. "Genome-wide analysis of Mycobacterium tuberculosis polymorphisms reveals lineage-specific associations with drug resistance". (2019): http://hdl.handle.net/10362/116707.
https://doi.org/10.1186/s12864-019-5615-3
- Diana Machado; Isabel Couto; Miguel Viveiros. "Advances in the molecular diagnosis of tuberculosis: From probes to genomes". Infection, Genetics and Evolution (2018): https://doi.org/10.1016/j.meegid.2018.11.021.
10.1016/j.meegid.2018.11.021
- Alexandra S Simões; M. R. Maia; J. Gregorio; Isabel Couto; A. M. Asfeldt; G. S. Simonsen; Pedro Povoa; Miguel Viveiros; Luís Velez Lapão. "Participatory implementation of an antibiotic stewardship programme supported by an innovative surveillance and clinical decision-support system". Journal of Hospital Infection 100 3 (2018): 257-264. https://research.unl.pt/en/publications/participatory-implementation-of-an-antibiotic-stewardship-programme-supported-by-an-innovative-surveillance-and-clinical-decisionsupport-system(1b84098f-0e69-4114-b624-d8daea97b98c).html.
10.1016/j.jhin.2018.07.034
- Luís Velez Lapão; Mélanie R. Maia; João Gregório; Isabel Couto; Pedro Povoa; Miguel Viveiros; Velez Lapao, L; et al. "Innovative Implementation of Antibiotic Stewardship supported by a Clinical Decision System". The European Journal of Public Health Vol. 28 supl. 4 (2018): 1-1. https://unl.elsevierpure.com/en/publications/3826e005-e0de-451d-b49a-e4bfb3322d20.
10.1093/eurpub/cky213.547
- Benjamin Sobkowiak; Judith R. Glynn; Rein M.G.J. Houben; Kim Mallard; Jody E. Phelan; José Afonso Guerra-Assunção; Louis Banda; et al. "Identifying mixed Mycobacterium tuberculosis infections from whole genome sequence data". BMC Genomics 19 1 (2018): https://research.unl.pt/en/publications/identifying-mixed-mycobacterium-tuberculosis-infections-from-whole-genome-sequence-data(5a159068-38b7-4eea-bdec-dd88c0baad60).html.
10.1186/s12864-018-4988-z
- Moisés Francisco; Sofia Santos Costa; Adriana Belas; Jorge Ramos; Isabel Couto; Constança Pomba; Miguel Viveiros. "First report on antimicrobial resistance and molecular characterisation of Salmonella enterica serotype Typhi isolated from human specimens in Luanda, Angola". Journal of Global Antimicrobial Resistance 13 (2018): 246-249. https://doi.org/10.1016/j.jgar.2018.02.001.
10.1016/j.jgar.2018.02.001
- Ramis IB; Vianna JS; Reis AJ; von Groll A; Ramos DF; Viveiros M; da Silva PEA. "Antimicrobial and Efflux Inhibitor Activity of Usnic Acid Against Mycobacterium abscessus.". Planta medica (2018): http://europepmc.org/abstract/med/29913527.
10.1055/a-0639-5412
- Machado D; Antunes J; Simões A; Perdigão J; Couto I; McCusker M; Martins M; et al. "Contribution of efflux to colistin heteroresistance in a multidrug resistant Acinetobacter baumannii clinical isolate.". Journal of medical microbiology (2018): http://europepmc.org/abstract/med/29717972.
10.1099/jmm.0.000741
- A. Tavares; A. Garcia; Abecasis AB; Miguel Viveiros; Sónia Dias. "Perspectives of health care providers in Portugal on the provision of care to migrant patients with TB or HIV-TB co-infection". European Journal of Public Health 28 (2018): 161-161. https://unl.elsevierpure.com/en/publications/88ef6e8e-51ed-4d48-a721-1c0950454fa7.
doi.org/10.1093/eurpub/cky048.151
- Coll F; Phelan J; Hill-Cawthorne GA; Nair MB; Mallard K; Ali S; Abdallah AM; et al. "Author Correction: Genome-wide analysis of multi- and extensively drug-resistant Mycobacterium tuberculosis.". Nature genetics (2018): http://europepmc.org/abstract/med/29674744.
10.1038/s41588-018-0074-3
- Deveson Lucas D; Crane B; Wright A; Han ML; Moffatt J; Bulach D; Gladman SL; et al. "Emergence of high-level colistin resistance in an Acinetobacter baumannii clinical isolate mediated by inactivation of the global regulator H-NS.". Antimicrobial agents and chemotherapy (2018): http://europepmc.org/abstract/med/29712662.
10.1128/aac.02442-17
- Diana Machado; João Perdigão; Isabel Portugal; Marco Pieroni; Pedro Silva; Isabel Couto; Miguel Viveiros. "Efflux Activity Differentially Modulates the Levels of Isoniazid and Rifampicin Resistance among Multidrug Resistant and Monoresistant Mycobacterium tuberculosis Strains". Antibiotics 7 1 (2018): 18-18. https://doi.org/10.3390/antibiotics7010018.
10.3390/antibiotics7010018
- Perdigão J; Silva C; Diniz J; Pereira C; Machado D; Ramos J; Silva H; et al. "Clonal expansion across the seas as seen through CPLP-TB database: A joint effort in cataloguing Mycobacterium tuberculosis genetic diversity in Portuguese-speaking countries.". Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases (2018): http://europepmc.org/abstract/med/29559379.
10.1016/j.meegid.2018.03.011
- Francesc Coll; Jody Phelan; Grant A Hill-Cawthorne; Mridul B Nair; Kim Mallard; Shahjahan Ali; Abdallah M Abdallah; et al. "Genome-wide analysis of multi- and extensively drug-resistant Mycobacterium tuberculosis". Nature Genetics 50 2 (2018): 307-316. https://research.unl.pt/en/publications/genomewide-analysis-of-multi-and-extensively-drugresistant-mycobacterium-tuberculosis(08c685f9-703c-4b58-a15c-79a4cd7ec5d0).html.
10.1038/s41588-017-0029-0
- Phelan J; de Sessions PF; Tientcheu L; Perdigao J; Machado D; Hasan R; Hasan Z; et al. "Methylation in Mycobacterium tuberculosis is lineage specific with associated mutations present globally.". Scientific reports (2018): http://europepmc.org/abstract/med/29317751.
10.1038/s41598-017-18188-y
- Simões AS; Alves DA; Gregório J; Couto I; Dias S; Póvoa P; Viveiros M; Gonçalves L; Lapão LV. "Fighting antibiotic resistance in Portuguese Hospitals: understanding antibiotic prescription behaviors to better design antibiotic stewardship programs.". Journal of global antimicrobial resistance (2018): http://europepmc.org/abstract/med/29409949.
10.1016/j.jgar.2018.01.013
- Costa, SS; Viveiros, M; Pomba, C; Couto, I. "Active antimicrobial efflux in Staphylococcus epidermidis: building up of resistance to fluoroquinolones and biocides in a major opportunistic pathogen". JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2018):
10.1093/jac/dkx400
- Machado, D; Lecorche, E; Mougari, F; Cambau, E; Viveiros, M; Machado, Diana; Lecorche, Emmanuel; et al. "Insights on Mycobacterium leprae Efflux Pumps and Their Implications in Drug Resistance and Virulence". FRONTIERS IN MICROBIOLOGY (2018): http://hdl.handle.net/10362/116694.
10.3389/fmicb.2018.03072
- Brynildsrud, OB; Pepperell, CS; Suffys, P; Grandjean, L; Monteserin, J; Debech, N; Bohlin, J; et al. "Global expansion of Mycobacterium tuberculosis lineage 4 shaped by colonial migration and local adaptation". SCIENCE ADVANCES (2018):
10.1126/sciadv.aat5869
- Sobkowiak, Benjamin; Glynn, Judith R.; Houben, Rein M.G.J.; Mallard, Kim; Phelan, Jody E.; Guerra-Assunção, José Afonso; Banda, Louis; et al. "Identifying mixed Mycobacterium tuberculosis infections from whole genome sequence data". (2018): http://hdl.handle.net/10362/116846.
https://doi.org/10.1186/s12864-018-4988-z
- Brynildsrud, Ola B.; Pepperell, Caitlin S.; Suffys, Philip; Grandjean, Louis; Monteserin, Johana; Debech, Nadia; Bohlin, Jon; et al. "Global expansion of Mycobacterium tuberculosis lineage 4 shaped by colonial migration and local adaptation". (2018): http://hdl.handle.net/10362/116688.
https://doi.org/10.1126/sciadv.aat5869
- Phelan, Jody; De Sessions, Paola Florez; Tientcheu, Leopold; Perdigao, Joao; Machado, Diana; Hasan, Rumina; Hasan, Zahra; et al. "Methylation in Mycobacterium tuberculosis is lineage specific with associated mutations present globally". (2018): http://hdl.handle.net/10362/116703.
https://doi.org/10.1038/s41598-017-18188-y
- Viveiros, Miguel; Matos, Olga; Conceição, Cláudia; Cruz, Deolinda; Rosado Pinto, José; Conceição, Cláudia; Viveiros, Miguel; et al. "4th National Congress of Tropical Medicine and 1st Lusophone Meeting on AIDS, Tuberculosis and Opportunistic Diseases". The Institute of Hygiene and Tropical Medicine in Lisbon (IHMT) and the Association for the Development of Tropical Medicine (ADMT) organized the 4th National Congress of Tropical Medicine (CNMT) on April 19-21, 2017 in Lisbon in tandem with the 1st Lusophone Meeting on AIDS, Tuberculosis and Opportunistic Diseases, integrating the 115th anniversary of the IHMT. This biennial event brought togethe (2018): https://doi.org/10.25761/anaisihmt.20.
https://doi.org/10.25761/anaisihmt.20
- Castro, Rita; Costa, João; Couto, Isabel; Vieira, Maria Luísa; Viveiros, Miguel; Rita Castro; J Costa; et al. "INFEÇÕES BACTERIANAS NEGLIGENCIADAS, ESQUECIDAS OU DESCONHECIDAS? A TRADIÇÃO EXÓTICA DO IHMT". . 11 (2018): https://doi.org/10.25761/anaisihmt.212.
https://doi.org/10.25761/anaisihmt.212
- Viveiros, Miguel. "O ENSINO DAS CIÊNCIAS MÉDICAS E BIOMÉDICAS NO INSTITUTO DE HIGIENE E MEDICINA TROPICAL – A CONTEXTUALIZAÇÃO HISTÓRICO-PEDAGÓGICO". . (2018): https://doi.org/10.25761/anaisihmt.233.
https://doi.org/10.25761/anaisihmt.233
- Viveiros, Miguel. "Activity of rifabutin and hemi-synthetic derivatives against Mycobacterium abscessus.". Medicinal chemistry (Shariqah (United Arab Emirates)) (2017): http://europepmc.org/abstract/med/29205119.
10.2174/1573406414666171204102633
- Rolando Cannalire; Diana Machado; Tommaso Felicetti; Sofia Santos Costa; Serena Massari; Giuseppe Manfroni; Maria Letizia Barreca; et al. "Natural isoflavone biochanin A as a template for the design of new and potent 3-phenylquinolone efflux inhibitors against Mycobacterium avium". European Journal of Medicinal Chemistry 140 (2017): 321-330. https://research.unl.pt/en/publications/natural-isoflavone-biochanin-a-as-a-template-for-the-design-of-new-and-potent-3phenylquinolone-efflux-inhibitors-against-mycobacterium-avium(671a32ce-545c-4997-a030-d79c019e8eba).html.
10.1016/j.ejmech.2017.09.014
- Diogo Vila-Viçosa; Bruno L Victor; Jorge Ramos; Diana Machado; Miguel Viveiros; Jacek Switala; Peter C Loewen; et al. "Insights on the mechanism of action of INH-C10 as an antitubercular prodrug". Molecular pharmaceutics 14 12 (2017): https://research.unl.pt/en/publications/insights-on-the-mechanism-of-action-of-inhc10-as-an-antitubercular-prodrug(88307fd0-7d81-4ff4-b5ef-52ab3a17134d).html.
10.1021/acs.molpharmaceut.7b00719
- Yoshio Nakatani; Helen K Opel-Reading; Matthias Merker; Diana Machado; Sönke Andres; S Siva Kumar; Danesh Moradigaravand; et al. "Role of alanine racemase mutations in Mycobacterium tuberculosis D-cycloserine resistance". Antimicrobial Agents and Chemotherapy 61 12 (2017): https://research.unl.pt/en/publications/role-of-alanine-racemase-mutations-in-mycobacterium-tuberculosis-dcycloserine-resistance(ba3b15cd-2ab2-4c72-981d-1f70b4d99862).html.
10.1128/AAC.01575-17
- Tavares, Ana Maria; Fronteira, Inês; Couto, Isabel; Machado, Diana; Viveiros, Miguel; Abecasis, Ana B.; Dias, Sónia; et al. "HIV and tuberculosis co-infection among migrants in Europe: A systematic review on the prevalence, incidence and mortality". PLOS ONE 12 9 (2017): e0185526. http://dx.doi.org/10.1371/journal.pone.0185526.
10.1371/journal.pone.0185526
- Elisa Azzali; Diana Machado; Amit Kaushik; Federica Vacondio; Sara Flisi; Clotilde Silvia Cabassi; Gyanu Lamichhane; et al. "Substituted N-Phenyl-5-(2-(phenylamino)thiazol-4-yl)isoxazole-3-carboxamides Are Valuable Antitubercular Candidates that Evade Innate Efflux Machinery". Journal Of Medicinal Chemistry (2017): 7108-7108. https://research.unl.pt/en/publications/substituted-nphenyl52phenylaminothiazol4ylisoxazole3carboxamides-are-valuable-antitubercular-candidates-that-evade-innate-efflux-machinery(897491b3-e688-47ad-8a5f-a8d8261f676a).html.
10.1021/acs.jmedchem.7b00793
- Viveiros, Miguel. "Detection of tuberculosis drug resistance: a comparison by Mycobacterium tuberculosis MLPA assay versus Genotype®MTBDRplus.". Memorias do Instituto Oswaldo Cruz (2017): http://europepmc.org/abstract/med/28591399.
10.1590/0074-02760160376
- Schön, T.; Miotto, P.; Köser, C.U.; Viveiros, M.; Böttger, E.; Cambau, E.. "Mycobacterium tuberculosis drug-resistance testing: challenges, recent developments and perspectives". Clinical Microbiology and Infection 23 3 (2017): 154-160. http://dx.doi.org/10.1016/j.cmi.2016.10.022.
10.1016/j.cmi.2016.10.022
- Guerreiro, Cátia Sá; Hartz, Zulmira; Sambo, Luís; Conceição, Cláudia; Dussault, Gilles; Russo, Giuliano; Viveiros, Miguel; et al. "Política de Investigação Científica para a Saúde em Portugal: II – Factos e Sugestões". Acta Médica Portuguesa 30 3 (2017): 233. http://dx.doi.org/10.20344/amp.8012.
10.20344/amp.8012
- Sá Guerreiro, Cátia; Hartz, Zulmira; Sambo, Luís; Conceição, Cláudia; Dussault, Gilles; Russo, Giuliano; Viveiros, Miguel; et al. "Política de Investigação Científica para a Saúde em Portugal: I - Enquadramento Europeu e Nacional". Acta Médica Portuguesa 30 2 (2017): 141. http://dx.doi.org/10.20344/amp.8011.
10.20344/amp.8011
- João Perdigão; Sofia Clemente; Jorge Ramos; Pedro Masakidi; Diana Machado; Carla Silva; Isabel Couto; et al. "Genetic diversity, transmission dynamics and drug resistance of Mycobacterium tuberculosis in Angola". Scientific Reports 7 1 (2017): 42814-42814. https://research.unl.pt/en/publications/genetic-diversity-transmission-dynamics-and-drug-resistance-of-mycobacterium-tuberculosis-in-angola(cba65502-3f10-4de0-b2cf-7b06d66c9450).html.
10.1038/srep42814
- Ana Soares; Mónica S Estevão; M. Manuel B. Marques; Vasily Kovalishyn; Diogo A R S Latino; Joao Aires-de-Sousa; Jorge Ramos; Miguel Viveiros; Filomena Martins. "Synthesis and Biological Evaluation of Hybrid 1,5- and 2,5-Disubstituted Indoles as Potentially New Antitubercular Agents". Journal Of Medicinal Chemistry 13 5 (2017): 439-439. https://research.unl.pt/en/publications/synthesis-and-biological-evaluation-of-hybrid-15-and-25disubstituted-indoles-as-potentially-new-antitubercular-agents(b8ab96c2-2ef3-46d9-ad19-4d948f399fa3).html.
10.2174/1573406413666170209144003
- Bettencourt, Miguel; L Amaral; Diane Ordway; Miguel Viveiros; M Martins; C Leandro; Amaral, Leonard; et al. "Thioridazine: A Non-Antibiotic Drug Highly Effective, in Combination with First Line Anti-Tuberculosis Drugs, against Any Form of Antibiotic Resistance of <em>Mycobacterium tuberculosis</em> Due to Its Multi-Mechanisms of Action". Antibiotics (2017): http://www.mdpi.com/2079-6382/6/1/3.
10.3390/antibiotics6010003
- Silva L; Carrion LL; von Groll A; Costa SS; Junqueir E; Ramos DF; Cantos J; et al. "In vitro and in silico analysis of the efficiency of tetrahydropyridines as drug efflux inhibitors in Escherichia coli.". International Journal of Antimicrobial Agents 49 3 (2017): 1-3. http://europepmc.org/abstract/med/28153476.
10.1016/j.ijantimicag.2016.11.024
- Diana Machado; Tatiane S Coelho; João Perdigão; Catarina Pereira; Isabel Couto; Isabel Portugal; Raquel De Abreu Maschmann; et al. "Interplay between Mutations and Efflux in Drug Resistant Clinical Isolates of Mycobacterium tuberculosis". Frontiers in Microbiology 8 (2017): 711-711. https://research.unl.pt/en/publications/interplay-between-mutations-and-efflux-in-drug-resistant-clinical-isolates-of-mycobacterium-tuberculosis(26dcab5e-97f6-4c2b-a305-f0ece9e75609).html.
10.3389/fmicb.2017.00711
- Sandra A. Morais; Virginia Moneti; Joana Silva; Karen Pereira; Marta Manso; Teresa Vilaça Santos; Vera Falcão; et al. "Tuberculose extensivamente resistente: uma realidade presente. Revisão da literatura a propósito de um caso clínico.". Revista Portuguesa de Doenças Infecciosas (2017): https://research.unl.pt/en/publications/tuberculose-extensivamente-resistente-uma-realidade-presente-revisao-da-literatura-a-proposito-de-um-caso-clinico(267c92fc-6bde-4450-9c3c-35a22f5b7ed7).html.
- Machado, D.; Fernandes, L.; Costa, S.S.; Cannalire, R.; Manfroni, G.; Tabarrini, O.; Couto, I.; et al. "Mode of action of the 2-phenylquinoline efflux inhibitor PQQ4R against Escherichia coli". PeerJ 2017 4 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85018654266&partnerID=MN8TOARS.
10.7717/peerj.3168
- Nakatani, Yoshio; Opel-Reading, Helen K; Merker, Matthias; Machado, Diana; Andres, Sönke; Kumar, S Siva; Moradigaravand, Danesh; et al. "Role of alanine racemase mutations in Mycobacterium tuberculosis D-cycloserine resistance". (2017): http://hdl.handle.net/10362/32683.
https://doi.org/10.1128/AAC.01575-17
- Sá Guerreiro, Cátia; Hartz, Zulmira; Sambo, Luís; Conceição, Cláudia; Dussault, Gilles; Russo, G; Viveiros, Miguel; et al. "Política de investigação científica para a saúde em Portugal". Acta Médica Portuguesa 30 3 (2017): 233-242. http://hdl.handle.net/10362/36435.
https://doi.org/10.20344/amp.8012
- Guerreiro, Cátia Sá; Hartz, Zulmira; Sambo, Luís; Conceição, Cláudia; Dussault, Gilles; Russo, Giuliano; Viveiros, Miguel; et al. "Scientific Research Policy for Health in Portugal: II - Facts and Suggestions". (2017): https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/8012.
- Sá Guerreiro, Cátia; Hartz, Zulmira; Sambo, Luís; Conceição, Cláudia; Dussault, Gilles; Russo, Giuliano; Viveiros, Miguel; et al. "Scientific Research Policy for Health in Portugal: I - European and National Environment". (2017): https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/8011.
- Jody Phelan; Denise M. O'Sullivan; Diana Machado; Jorge Ramos; Alexandra S. Whale; Justin O'Grady; Keertan Dheda; et al. "The variability and reproducibility of whole genome sequencing technology for detecting resistance to anti-tuberculous drugs". Genome Medicine 8 1 (2016): https://research.unl.pt/en/publications/the-variability-and-reproducibility-of-whole-genome-sequencing-technology-for-detecting-resistance-to-antituberculous-drugs(9f7fd63d-cdfe-4848-8253-057aa8579cb0).html.
10.1186/s13073-016-0385-x
- Sofia Santos Costa; Cláudia Palma; Kristina Kadlec; Andrea T. Fessler; Miguel Viveiros; José Melo-Cristino; Stefan Schwarz; Isabel Couto. "Plasmid-borne antimicrobial resistance of staphylococcus aureus isolated in a hospital in Lisbon, Portugal". Microbial Drug Resistance 22 8 (2016): 617-626. https://research.unl.pt/en/publications/plasmidborne-antimicrobial-resistance-of-staphylococcus-aureus-isolated-in-a-hospital-in-lisbon-portugal(c958cee5-7d8c-4cc6-ade6-34077b2064a3).html.
10.1089/mdr.2015.0352
- J Perdigão; F Maltez; Diana Machado; H Silveira; C Pereira; C Silva; Isabel Couto; Miguel Viveiros; I Portugal. "Beyond extensively drug-resistant tuberculosis in Lisbon, Portugal". International Journal Of Antimicrobial Agents 48 5 (2016): 569-570. https://research.unl.pt/en/publications/beyond-extensively-drugresistant-tuberculosis-in-lisbon-portugal(90dceb78-989b-43ea-8b57-b2e1193e4979).html.
10.1016/j.ijantimicag.2016.07.026
- Sofia Santos Costa; Elizeth Lopes; Elisa Azzali; Diana Machado; Tatiane Coelho; Pedro Eduardo Almeida Da Silva; Miguel Viveiros; Marco Pieroni; Isabel Couto. "An Experimental Model for the Rapid Screening of Compounds with Potential Use Against Mycobacteria". Assay and Drug Development Technologies 14 9 (2016): 524-534. https://research.unl.pt/en/publications/an-experimental-model-for-the-rapid-screening-of-compounds-with-potential-use-against-mycobacteria(49709c9e-e92e-4438-830b-60cd071815b5).html.
10.1089/adt.2016.752
- Phelan, Jody E.; Coll, Francesc; Bergval, Indra; Anthony, Richard M.; Warren, Rob; Sampson, Samantha L.; Gey van Pittius, Nicolaas C.; et al. "Recombination in pe/ppe genes contributes to genetic variation in Mycobacterium tuberculosis lineages". BMC Genomics 17 1 (2016): http://dx.doi.org/10.1186/s12864-016-2467-y.
10.1186/s12864-016-2467-y
- Machado, D.; Cannalire, R.; Santos Costa, S.; Manfroni, G.; Tabarrini, O.; Cecchetti, V.; Couto, I.; Viveiros, M.; Sabatini, S.. "Boosting Effect of 2-Phenylquinoline Efflux Inhibitors in Combination with Macrolides against Mycobacterium smegmatis and Mycobacterium avium". ACS Infectious Diseases 1 12 (2016): 593-603. http://www.scopus.com/inward/record.url?eid=2-s2.0-84969256572&partnerID=MN8TOARS.
10.1021/acsinfecdis.5b00052
- Phelan, Jody; O'Sullivan, Denise M.; Machado, Diana; Ramos, Jorge; Whale, Alexandra S.; O'Grady, Justin; Dheda, Keertan; et al. "The variability and reproducibility of whole genome sequencing technology for detecting resistance to anti-tuberculous drugs". (2016): http://www.scopus.com/inward/record.url?scp=85006757655&partnerID=8YFLogxK.
https://doi.org/10.1186/s13073-016-0385-x
- Machado, Diana; Pires, David; Perdigão, João; Couto, Isabel; Portugal, Isabel; Martins, Marta; Amaral, Leonard; et al. "Ion channel blockers as antimicrobial agents, efflux inhibitors, and enhancers of macrophage killing activity against drug resistant mycobacterium tuberculosis". PLOS ONE 11 2 (2016): e0149326. http://www.scopus.com/inward/record.url?scp=84960338991&partnerID=8YFLogxK.
https://doi.org/10.1371/journal.pone.0149326
- Miguel Viveiros; MJ Simões. "Pequena história da RIDES-Tuberculose no âmbito do Plano Estratégico de Cooperação em saúde 2009-2012 da Comunidade dos Países de Língua Portuguesa". Anais Do Instituto De Higiene E Medicina Tropical 15 1 (2016): 45-50. https://novaresearch.unl.pt/en/publications/2a9026d1-aa7a-4a77-b1fe-688ca351356d.
- de Matos, Ana Cristina Outeiro Correia Outeiro Correia. "New Insights on Zoonotic and Non-zoonotic Mycobacteriosis in Wild Mammals in Portugal: Epidemiological and Histopathological Aspects". Universidade de Tras-os-Montes E Alto Douro (Portugal) (2016): https://publons.com/wos-op/publon/64843843/.
- Elis R. Dalla Costa; Sidra E G Vasconcelos; Leonardo S. Esteves; Harrison M. Gomes; Lia L. Gomes; Pedro Almeida Da Silva; João Perdigão; et al. "Multidrug-resistant mycobacterium tuberculosis of the Latin American mediterranean lineage, wrongly identified as mycobacterium pinnipedii (Spoligotype International Type 863 [SIT863]), causing active tuberculosis in South Brazil". Journal Of Clinical Microbiology 53 12 (2015): 3805-3811. https://research.unl.pt/en/publications/multidrugresistant-mycobacterium-tuberculosis-of-the-latin-american-mediterranean-lineage-wrongly-identified-as-mycobacterium-pinnipedii-spoligotype-international-type-863-sit863-causing-active-tuber(3bcb74ef-5a7c-4.
10.1128/JCM.02012-15
- Francesc Coll; Ruth McNerney; Mark D. Preston; José Afonso Guerra-Assunção; Andrew Warry; Grant Hill-Cawthorne; Kim Mallard; et al. "Rapid determination of anti-tuberculosis drug resistance from whole-genome sequences". Genome Medicine 7 1 (2015): https://research.unl.pt/en/publications/rapid-determination-of-antituberculosis-drug-resistance-from-wholegenome-sequences(d8f4e4e6-76c2-4f7c-bb4f-15e9c0e8e9ab).html.
10.1186/s13073-015-0164-0
- Isabel Couto; Miguel Viveiros. "Breve história da micobacteriologia no IHMT/UNL". Anais do Instituto de Higiene e Medicina Tropical 13 (2015): 29-35. https://research.unl.pt/en/publications/breve-historia-da-micobacteriologia-no-ihmtunl(d4629590-1023-4e29-ba9a-a75c8b5341e3).html.
https://doi.org/10.25761/anaisihmt.168
- Cambau, E.; Viveiros, M.; Machado, D.; Raskine, L.; Ritter, C.; Tortoli, E.; Matthys, V.; et al. "Revisiting susceptibility testing in MDR-TB by a standardized quantitative phenotypic assessment in a European multicentre study". Journal of Antimicrobial Chemotherapy 70 3 (2015): 686-696. http://www.scopus.com/inward/record.url?eid=2-s2.0-84928183832&partnerID=MN8TOARS.
10.1093/jac/dku438
- Cabral, V.; Luo, X.; Junqueira, E.; Costa, S.S.; Mulhovo, S.; Duarte, A.; Couto, I.; Viveiros, M.; Ferreira, M.-J.U.. "Enhancing activity of antibiotics against Staphylococcus aureus: Zanthoxylum capense constituents and derivatives". Phytomedicine 22 4 (2015): 469-476. http://www.scopus.com/inward/record.url?eid=2-s2.0-84964270861&partnerID=MN8TOARS.
10.1016/j.phymed.2015.02.003
- Pinto-Almeida, A.; Mendes, T.; Armada, A.; Belo, S.; Carrilho, E.; Viveiros, M.; Afonso, A.. "The role of efflux pumps in Schistosoma mansoni Praziquantel resistant phenotype". PLoS ONE 10 10 (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84948692444&partnerID=MN8TOARS.
10.1371/journal.pone.0140147
- Coelho, T.; Machado, D.; Couto, I.; Maschmann, R.; Ramos, D.; Groll, A.; Rossetti, M.L.; Silva, P.A.; Viveiros, M.. "Enhancement of antibiotic activity by efflux inhibitors against multidrug resistant Mycobacterium tuberculosis clinical isolates from Brazil". Frontiers in Microbiology 6 APR (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84930941347&partnerID=MN8TOARS.
10.3389/fmicb.2015.00330
- Perdigão, J.; Silva, H.; Machado, D.; Macedo, R.; Maltez, F.; Silva, C.; Jordao, L.; et al. "Genomic diversity of drug-resistant Mycobacterium tuberculosis isolates in Lisbon Portugal: Towards tuberculosis genomic epidemiology". International Journal of Mycobacteriology (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84921367931&partnerID=MN8TOARS.
10.1016/j.ijmyco.2015.01.001
- Pinto-Almeida, António; Mendes, Tiago; Armada, Ana; Belo, Silvana; Carrilho, Emanuel; Viveiros, Miguel; Afonso, Ana; et al. "The role of efflux pumps in Schistosoma mansoni Praziquantel resistant phenotype". (2015): http://www.scopus.com/inward/record.url?scp=84948692444&partnerID=8YFLogxK.
https://doi.org/10.1371/journal.pone.0140147
- Rabna, Paulo; Ramos, Jorge; Ponce, Gema; Sanca, Lilica; Mané, Morto; Armada, Ana; Machado, Diana; et al. "Direct detection by the xpert MTB/RIF assay and characterization of multi and poly drug- resistant tuberculosis in Guinea-Bissau, West Africa". PLOS ONE 10 5 (2015): e0127536. http://www.scopus.com/inward/record.url?scp=84958198245&partnerID=8YFLogxK.
https://doi.org/10.1371/journal.pone.0127536
- Costa, Sofia Santos; Viveiros, Miguel; Rosato, Adriana E.; Melo-Cristino, José; Couto, Isabel; TB, HIV and opportunistic diseases and pathogens (THOP); Global Health and Tropical Medicine (GHTM); et al. "Impact of efflux in the development of multidrug resistance phenotypes in Staphylococcus aureus Clinical microbiology and vaccines". Bmc Microbiology 15 1 (2015): http://www.scopus.com/inward/record.url?scp=84945118570&partnerID=8YFLogxK.
https://doi.org/10.1186/s12866-015-0572-8
- Coelho, Tatiane; Machado, Diana; Couto, Isabel; Maschmann, Raquel; Ramos, Daniela; Groll, Andrea von; Rossetti, Maria L.; et al. "Enhancement of antibiotic activity by efflux inhibitors against multidrug resistant Mycobacterium tuberculosis clinical isolates from Brazil". (2015): http://www.scopus.com/inward/record.url?scp=84930941347&partnerID=8YFLogxK.
https://doi.org/10.3389/fmicb.2015.00330
- Dalla Costa, Elis R.; Vasconcelos, Sidra E G; Esteves, Leonardo S.; Gomes, Harrison M.; Gomes, Lia L.; Da Silva, Pedro Almeida; Perdigão, João; et al. "Multidrug-resistant mycobacterium tuberculosis of the Latin American mediterranean lineage, wrongly identified as mycobacterium pinnipedii (Spoligotype International Type 863 [SIT863]), causing active tuberculosis in South Brazil". (2015): http://www.scopus.com/inward/record.url?scp=84947775741&partnerID=8YFLogxK.
https://doi.org/10.1128/JCM.02012-15
- Pieroni, M.; Machado, D.; Azzali, E.; Santos Costa, S.; Couto, I.; Costantino, G.; Viveiros, M.. "Rational Design and Synthesis of Thioridazine Analogues as Enhancers of the Antituberculosis Therapy". Journal of Medicinal Chemistry 58 15 (2015): 5842-5853. http://www.scopus.com/inward/record.url?eid=2-s2.0-84939125634&partnerID=MN8TOARS.
10.1021/acs.jmedchem.5b00428
- Célia Leão; Ana Canto; Diana Machado; Ilda Santos Sanches; Isabel Couto; Miguel Viveiros; João Inácio; Ana Botelho. "Relatedness of Mycobacterium avium subspecies hominissuis clinical isolates of human and porcine origins assessed by MLVA". Veterinary Microbiology 173 1-2 (2014): 92-100. https://research.unl.pt/en/publications/relatedness-of-mycobacterium-avium-subspecies-hominissuis-clinical-isolates-of-human-and-porcine-origins-assessed-by-mlva(fbddaea4-ee1b-4a32-9b94-b0d2e8e6f1ca).html.
10.1016/j.vetmic.2014.06.027
- Francesc Coll; Ruth McNerney; José Afonso Guerra-Assunção; Judith R. Glynn; João Perdigão; Miguel Viveiros; Isabel Portugal; et al. "A robust SNP barcode for typing Mycobacterium tuberculosis complex strains". NATURE COMMUNICATIONS 5 (2014): https://research.unl.pt/en/publications/a-robust-snp-barcode-for-typing-mycobacterium-tuberculosis-complex-strains(daca2113-5110-4d32-94f6-8415c90a70ac).html.
10.1038/ncomms5812
- Pedro Pedrosa; Bruno Veigas; Diana Machado; Isabel Couto; Miguel Viveiros; P. V. Baptista. "Gold nanoprobes for multi loci assessment of multi-drug resistant tuberculosis". Tuberculosis 94 3 (2014): 332-337. https://research.unl.pt/en/publications/gold-nanoprobes-for-multi-loci-assessment-of-multidrug-resistant-tuberculosis(0e5dc7d1-023f-414e-8149-1ffb9ed75cba).html.
10.1016/j.tube.2013.12.009
- Filomena Martins; Susana Santos; Cristina Ventura; Ruben Elvas-Leitão; Lidia Santos; Susana Vitorino; Marina Reis; et al. "Design, synthesis and biological evaluation of novel isoniazid derivatives with potent antitubercular activity.". European Journal Of Medicinal Chemistry 81C (2014): 119-138. https://research.unl.pt/en/publications/design-synthesis-and-biological-evaluation-of-novel-isoniazid-derivatives-with-potent-antitubercular-activity(c12c3c4a-6fc7-4143-9d65-725c51a2533f).html.
10.1016/j.ejmech.2014.04.077
- Pedro Costa; Ana Botelho; Isabel Couto; Miguel Viveiros; João Inácio; Costa, Pedro; Botelho, Ana R.; et al. "Standing of nucleic acid testing strategies in veterinary diagnosis laboratories to uncover Mycobacterium tuberculosis complex members". Frontiers in molecular biosciences 15 1 (2014): 16-16. https://research.unl.pt/en/publications/standing-of-nucleic-acid-testing-strategies-in-veterinary-diagnosis-laboratories-to-uncover-mycobacterium-tuberculosis-complex-members(f6c6f080-d462-433b-a86f-6ef17abe995e).html.
10.3389/fmolb.2014.00016
- Machado, D; Ramos, J; Couto, I; Cadir, N; Narciso, I; Coelho, E; Viegas, S; Viveiros, M. "Assessment of the BD MGIT TBc Identification Test for the Detection of Mycobacterium tuberculosis Complex in a Network of Mycobacteriology Laboratories". BIOMED RESEARCH INTERNATIONAL (2014):
10.1155/2014/398108
- Francesc Coll; Mark Preston; José Afonso Guerra-Assunção; Grant Hill-Cawthorn; David Harris; João Perdigão; Miguel Viveiros; et al. "PolyTB". Tuberculosis (Edinburgh, Scotland) 94 3 (2014): 346-354. https://research.unl.pt/en/publications/polytb(f050e743-ad4f-4f57-8cc1-9fa7a3645962).html.
10.1016/j.tube.2014.02.005
- Viveiros, M.; Pieroni, M.. "Spectinamides: A challenge, a proof, and a suggestion". Trends in Microbiology 22 4 (2014): 170-171. http://www.scopus.com/inward/record.url?eid=2-s2.0-84897434951&partnerID=MN8TOARS.
10.1016/j.tim.2014.02.008
- Pedro Costa; Ana Amaro; Ana S. Ferreira; Diana Machado; Teresa Albuquerque; Isabel Couto; Ana Botelho; et al. "Rapid identification of veterinary-relevant Mycobacterium tuberculosis complex species using 16S rDNA, IS6110 and Regions of Differencetargeted dual-labelled hydrolysis probes". Journal Of Microbiological Methods 107 (2014): 13-22. https://research.unl.pt/en/publications/rapid-identification-of-veterinaryrelevant-mycobacterium-tuberculosis-complex-species-using-16s-rdna-is6110-and-regions-of-differencetargeted-duallabelled-hydrolysis-probes(beeda4f4-a0ab-496b-a9a0-f5eacea15679).html.
10.1016/j.mimet.2014.08.017
- de Carvalho, C.C.C.R.; Costa, S.S.; Fernandes, P.; Couto, I.; Viveiros, M.; de Carvalho, Carla C C R; Costa, Sofia Maria Mourão Marques dos Santos; et al. "Membrane transport systems and the biodegradation potential and pathogenicity of genus Rhodococcus". Frontiers in Physiology 5 APR (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84901008267&partnerID=MN8TOARS.
10.3389/fphys.2014.00133
- Perdigão, João; Silva, Hugo; Machado, Diana; Macedo, Rita; Maltez, Fernando; Silva, Carla; Jordão, Luísa; et al. "Unraveling Mycobacterium tuberculosis genomic diversity and evolution in Lisbon, Portugal, a highly drug resistant setting". Bmc Genomics 15 (2014): 991-991. http://hdl.handle.net/10400.18/2931.
10.1186/1471-2164-15-991
- Martins, F.; Ventura, C.; Santos, S.; Viveiros, M.. "QSAR based design of new antitubercular compounds: Improved isoniazid derivatives against multidrug-resistant TB". Current Pharmaceutical Design 20 27 (2014): 4427-4454. http://www.scopus.com/inward/record.url?eid=2-s2.0-84904757088&partnerID=MN8TOARS.
10.2174/1381612819666131118164434
- Coll, Francesc; McNerney, Ruth; Guerra-Assunção, José Afonso; Glynn, Judith R.; Perdigão, João; Viveiros, Miguel; Portugal, Isabel; et al. "A robust SNP barcode for typing Mycobacterium tuberculosis complex strains". (2014): http://hdl.handle.net/10362/116795.
https://doi.org/10.1038/ncomms5812
- Machado, Diana; Ramos, Jorge; Couto, Isabel; Cadir, Nureisha; Narciso, Inácio; Coelho, Elizabeth; Viegas, Sofia; Viveiros, Miguel. "Assessment of the BD MGIT TBc identification test for the detection of mycobacterium tuberculosis complex in a network of mycobacteriology laboratories". (2014): http://hdl.handle.net/10362/116796.
https://doi.org/10.1155/2014/398108
- Pedro Costa; Ana S. Ferreira; Ana Amaro; Teresa Albuquerque; Ana Botelho; Isabel Couto; Mónica V. Cunha; et al. "Enhanced detection of tuberculous mycobacteria in animal tissues using a semi-nested probe-based real-time PCR". PLoS ONE 8 11 (2013): https://research.unl.pt/en/publications/enhanced-detection-of-tuberculous-mycobacteria-in-animal-tissues-using-a-seminested-probebased-realtime-pcr(d55534de-59e0-49b4-ab32-2226ae5085a4).html.
10.1371/journal.pone.0081337
- Ana Armada; Tatiana Alexandru; Diana Machado; Balazs Danko; Attila Hunyadi; Andra Dinache; Viorel Nastasa; et al. "The in vitro activity of products formed from exposure of chlorpromazine to a 266nm laser beam against species of mycobacteria of human interest". In vivo (Athens, Greece) 27 5 (2013): 605-610. https://research.unl.pt/en/publications/the-in-vitro-activity-of-products-formed-from-exposure-of-chlorpromazine-to-a-266nm-laser-beam-against-species-of-mycobacteria-of-human-interest(170bb203-57a9-4067-b045-3c8a91752d36).html.
- Sofia Santos Costa; Elisabete Junqueira; Cláudia Palma; Miguel Viveiros; José Melo-Cristino; Leonard Amaral; Isabel Couto. "Resistance to antimicrobials mediated by efflux pumps in Staphylococcus aureus". Antibiotics 2 1 (2013): 83-99. https://research.unl.pt/en/publications/resistance-to-antimicrobials-mediated-by-efflux-pumps-in-staphylococcus-aureus(c5ee046d-4c8e-4800-8548-3d7faf8f0b8c).html.
10.3390/antibiotics2010083
- Ana Armada; Miguel Viveiros; Leonard Amaral. "Biological evaluation of products formed from the irradiation of chlorpromazine with a 266 nm laser beam.". Biochemistry & Pharmacology - Open Access 2 NA (2013): 109-109. https://research.unl.pt/en/publications/biological-evaluation-of-products-formed-from-the-irradiation-of-chlorpromazine-with-a-266-nm-laser-beam(e8ea1b38-bb33-4ea2-8ac5-8868b233d91b).html.
- J Perdigão; R., Macedo,; C., Silva,; Diana Machado; Isabel Couto; Miguel Viveiros; L., Jordao,; et al. "From multidrug-resistant to extensively drug-resistant tuberculosis in Lisbon, Portugal: the stepwise mode of resistance acquisition.". Journal of Antimicrobial Chemotherapy 68 1 (2013): 27-33. https://research.unl.pt/en/publications/from-multidrugresistant-to-extensively-drugresistant-tuberculosis-in-lisbon-portugal-the-stepwise-mode-of-resistance-acquisition(f70530b4-0075-4d58-8900-f431450e2874).html.
10.1093/jac/dks371
- Abecasis AB; Miguel Viveiros; Leonard Amaral. "Activity of the efflux pump inhibitor SILA 421 against drug-resistant tuberculosis.". International Journal Of Antimicrobial Agents 41 5 (2013): 488-489. https://research.unl.pt/en/publications/activity-of-the-efflux-pump-inhibitor-sila-421-against-drugresistant-tuberculosis(45e829ee-e540-4800-bb87-d02985173041).html.
10.1016/j.ijantimicag.2013.01.001
- Sofia Santos Costa; C., Mourato,; Miguel Viveiros; J., Melo- Cristino,; Leonard Amaral; Isabel Couto. "Description of plasmid pSM52, harbouring the gene for the Smr efflux pump, and its involvement in resistance to biocides in a meticillin-resistant Staphylococcus aureus strain.". International Journal Of Antimicrobial Agents 41 (2013): https://research.unl.pt/en/publications/description-of-plasmid-psm52-harbouring-the-gene-for-the-smr-efflux-pump-and-its-involvement-in-resistance-to-biocides-in-a-meticillinresistant-staphylococcus-aureus-strain(2b79dedb-fd6e-46a0-9aaa-a87bdd957d1c).html.
10.1016/j.ijantimicag.2013.01.003
- Miguel Viveiros; Diana Machado; J Perdigão; J, Ramos; Isabel Couto; I, Portugal; C. Ritter; E.C., Boettger,. "High-level resistance to isoniazid and ethionamide in multidrug-resistant Mycobacterium tuberculosis of the Lisboa family is associated with inhA double mutations.". Journal of Antimicrobial Chemotherapy 68 8 (2013): 1728-32. https://research.unl.pt/en/publications/highlevel-resistance-to-isoniazid-and-ethionamide-in-multidrugresistant-mycobacterium-tuberculosis-of-the-lisboa-family-is-associated-with-inha-double-mutations(ee32cb8e-627a-43a1-ab9d-bb5a9a980d2c).html.
10.1093/jac/dkt090
- Miguel Viveiros. "Role of the Mmr efflux pump in drug resistance in Mycobacterium tuberculosis.". Antimicrobial Agents And Chemotherapy 57 2 (2013): 751-7. https://research.unl.pt/en/publications/role-of-the-mmr-efflux-pump-in-drug-resistance-in-mycobacterium-tuberculosis(27f6e97f-ba86-469c-84fe-21722c84046c).html.
10.1128/aac.01482-12
- P. V. Baptista; Miguel Viveiros; Isabel Couto. "Isothermal DNA amplification coupled to Aunanoprobes for detection of mutations associated to Rifampicin resistance in Mycobacterium tuberculosis". Journal Of Nanobiotechnology 11 NA (2013): 38-38. https://research.unl.pt/en/publications/isothermal-dna-amplification-coupled-to-aunanoprobes-for-detection-of-mutations-associated-to-rifampicin-resistance-in-mycobacterium-tuberculosis(c1384fed-4794-4633-8b01-bbe0c27aedb0).html.
10.1186/1477-3155-11-38
- Leonard Amaral; Miguel Viveiros; Isabel Couto; Martins, Marta; McCusker, Matthew P.; Bettencourt, Miguel Viveiros; Couto, Isabel Maria dos Santos Leitão; et al. "A simple method for assessment of MDR bacteria for over-expressed efflux pumps.". Open Microbiology Journal 7 NA (2013): 72-82. https://research.unl.pt/en/publications/a-simple-method-for-assessment-of-mdr-bacteria-for-overexpressed-efflux-pumps(d873b843-79f0-490f-80b4-0ea7808a6f2f).html.
10.2174/1874285801307010072
- Sofia Santos Costa; Miguel Viveiros; Leonard Amaral; Isabel Couto; Costa, SS; Bettencourt, Miguel Viveiros; Amaral, Leonard; Couto, Isabel Maria dos Santos Leitão. "Multidrug efflux pumps in Staphylococcus aureus: an update.". Open Microbiology Journal 7 NA (2013): 59-71. https://research.unl.pt/en/publications/multidrug-efflux-pumps-in-staphylococcus-aureus-an-update(04af8331-c342-4bdb-8dde-3966a927d2bc).html.
10.2174/1874285801307010059
- Sofia Costa; Celeste Falcão; Miguel Viveiros; Diana Machado; Marta Martins; José Melo-Cristino; Leonard Amaral; Isabel Couto. "Correction: Exploring the contribution of efflux on the resistance to fluoroquinolones in clinical isolates of Staphylococcus aureus". BMC Microbiology 13 1 (2013): 127-127. http://dx.doi.org/10.1186/1471-2180-13-127.
10.1186/1471-2180-13-127
- Veigas, Bruno; Pedrosa, Pedro; Couto, Isabel; Viveiros, Miguel; Baptista, Pedro V.. "Isothermal DNA amplification coupled to Au-nanoprobes for detection of mutations associated to Rifampicin resistance in Mycobacterium tuberculosis". (2013): http://hdl.handle.net/10362/100686.
https://doi.org/10.1186/1477-3155-11-38
- Perdigão, joão; Macedo, Rita; Machado, Diana; Silva, Carla; Jordão, Luísa; Couto, Isabel; Viveiros, Miguel; et al. "GidB mutation as a phylogenetic marker for Q1 cluster Mycobacterium tuberculosis isolates and intermediate-level streptomycin resistance determinant in Lisbon, Portugal". Clinical Microbiology and Infection 20 5 (2013): https://www.authenticus.pt/P-010-V6K.
10.1111/1469-0691.12392
- Miguel Viveiros; Rodrigo Martins; Pedro Barquinha; Elvira Fortunato; P. V. Baptista. "Gold on paper-paper platform for Au-nanoprobe TB detection". Lab On A Chip 12 22 (2012): 4802-8. https://research.unl.pt/en/publications/gold-on-paperpaper-platform-for-aunanoprobe-tb-detection(0a0a1763-9d4b-404b-8ee7-7dcb84d82ce6).html.
10.1039/c2lc40739f
- Liliana Rodrigues; Diana Machado; Isabel Couto; Leonard Amaral; Miguel Viveiros. "Contribution of efflux activity to isoniazid resistance in the Mycobacterium tuberculosis complex". Infection Genetics And Evolution 12 4 (2012): 695-700. https://research.unl.pt/en/publications/contribution-of-efflux-activity-to-isoniazid-resistance-in-the-mycobacterium-tuberculosis-complex(f2c4ea6f-0c4b-4e78-a4c7-bcf78a21bdfc).html.
10.1016/j.meegid.2011.08.009
- Diana Machado; Isabel Couto; Liliana Rodrigues; P. V. Baptista; Bruno Veigas; Miguel Viveiros; Leonard Amaral. "Contribution of Efflux to the Emergence of Isoniazid and Multidrug Resistance in Mycobacterium tuberculosis.". Plos One 7 4 (2012): e34538-e34538. https://research.unl.pt/en/publications/contribution-of-efflux-to-the-emergence-of-isoniazid-and-multidrug-resistance-in-mycobacterium-tuberculosis(4f80727c-69c9-4c79-9e84-3a2fff2617e8).html.
10.1371/journal.pone.0034538
- Dymek A; Armada A; Handzlik J; Viveiros M; Spengler G; Molnar J; Kiec-Kononowicz K; Amaral L. "The activity of 16 new hydantoin compounds on the intrinsic and overexpressed efflux pump system of Staphylococcus aureus.". In Vivo (2012): http://europepmc.org/abstract/med/22351662.
- Leonard Amaral; Ana Martins; Miguel Viveiros; Isabel Couto; Sofia Santos Costa; Marta Martins. "Genetic response of Salmonella enterica serotype Enteritidis to thioridazine rendering the organism resistant to the agent.". International Journal Of Antimicrobial Agents 39 1 (2012): 16-21. https://research.unl.pt/en/publications/genetic-response-of-salmonella-enterica-serotype-enteritidis-to-thioridazine-rendering-the-organism-resistant-to-the-agent(9480871f-8741-4209-9d04-5f6377b5db67).html.
10.1016/j.ijantimicag.2011.08.013
- Miguel Viveiros; Leonard Amaral; Isabel Couto. "Inhibitors of mycobacterial efflux pumps as potential boosters for anti-tubercular drugs.". Expert Review Of Anti-Infective Therapy 10 9 (2012): 983-998. https://research.unl.pt/en/publications/inhibitors-of-mycobacterial-efflux-pumps-as-potential-boosters-for-antitubercular-drugs(268b7625-7450-4be5-abc3-32d4150d9b67).html.
10.1586/eri.12.89
- Miguel Viveiros; Isabel Couto. "Using Au-nanoprobes por point-of-need diagnostics of TB.". Microbiologia online 1 (2012): online-online. https://research.unl.pt/en/publications/using-aunanoprobes-por-pointofneed-diagnostics-of-tb(f61729c0-46ff-4d34-aaae-12eda27028f1).html.
- Leonard Amaral; Miguel Viveiros. "Why thioridazine in combination with antibiotics cures extensively drug-resistant Mycobacterium tuberculosis infections". International Journal Of Antimicrobial Agents 39 5 (2012): 376-380. https://research.unl.pt/en/publications/why-thioridazine-in-combination-with-antibiotics-cures-extensively-drugresistant-mycobacterium-tuberculosis-infections(16d0c0ce-904f-4288-84be-2893850e785e).html.
10.1016/j.ijantimicag.2012.01.012
- Miguel Viveiros. "Edição Comemorativa dos Anais: O ensino das ciências médicas e biomédicas no Instituto de Higiene e Medicina Tropical – a contextualização histórico-pedagógica.". Anais Do Instituto De Higiene E Medicina Tropical 11 (2012): https://research.unl.pt/en/publications/edicao-comemorativa-dos-anais-o-ensino-das-ciencias-medicas-e-biomedicas-no-instituto-de-higiene-e-medicina-tropical--a-contextualizacao-historicopedagogica(62bb4661-2cc6-4c1d-aa6c-744cd463c70b).html.
- Faculdade de Ciências. "Synthesis and thermochemical study of quinoxaline-N-oxides: enthalpies of dissociation of the N-O bond". (2012): 0894-3230.
10.1002/poc.1932
- Machado, D; Couto, Isabel Maria dos Santos Leitão; Perdigão, João; Rodrigues, Liliana; Portugal, Isabel; Baptista, Pedro; Veigas, Bruno; Amaral, Leonard; Bettencourt, Miguel Viveiros. "Contribution of Efflux to the Emergence of Isoniazid and Multidrug Resistance in Mycobacterium tuberculosis.". (2012): http://hdl.handle.net/10362/117077.
https://doi.org/10.1371/journal.pone.0034538
- Gabriella Spengler; Joseph Molnar; Miguel Viveiros; Leonard Amaral. "Thioridazine induces apoptosis of multidrug-resistant mouse lymphoma cells transfected with the human ABCB1 and inhibits the expression of P-glycoprotein". Anticancer Research 31 12 (2011): 4201-5. https://research.unl.pt/en/publications/thioridazine-induces-apoptosis-of-multidrugresistant-mouse-lymphoma-cells-transfected-with-the-human-abcb1-and-inhibits-the-expression-of-pglycoprotein(5fba65fc-e81c-4324-a696-0d117d45cc8b).html.
- Sofia Santos Costa; Celeste Falcão; Miguel Viveiros; Diana Machado; Marta Martins; José Melo-Cristino; Leonard Amaral; Isabel Couto. "Exploring the contribution of efflux on the resistance to fluoroquinolones in clinical isolates of Staphylococcus aureus". Bmc Microbiology 11 (2011): 241-241. https://research.unl.pt/en/publications/exploring-the-contribution-of-efflux-on-the-resistance-to-fluoroquinolones-in-clinical-isolates-of-staphylococcus-aureus(2d5a98ed-d260-4d76-bb02-5379b696ad01).html.
10.1186/1471-2180-11-241
- Spengler G; Handzlik J; Ocsovszki I; Viveiros M; Kiec-Kononowicz K; Molnar J; Amaral L. "Modulation of multidrug efflux pump activity by new hydantoin derivatives on colon adenocarcinoma cells without inducing apoptosis.". Anticancer research (2011): http://europepmc.org/abstract/med/21965738.
- Lisa Machado; Gabriella Spengler; Miguel Evaristo; Jadwiga Handzlik; Joseph Molnár; Miguel Viveiros; Katarzyna Kiec-Kononowicz; Leonard Amaral. "Biological activity of twenty-three hydantoin derivatives on intrinsic efflux pump system of Salmonella enterica serovar enteritidis NCTC 13349". In Vivo 25 5 (2011): 769-772. https://research.unl.pt/en/publications/biological-activity-of-twentythree-hydantoin-derivatives-on-intrinsic-efflux-pump-system-of-salmonella-enterica-serovar-enteritidis-nctc-13349(c1e82ed5-027d-4c99-91d8-52230b623f5a).html.
- Daniella Takács; Pedro Cerca; Ana Martins; Zsuzsanna Riedl; György Hajós; Joseph Molnár; Miguel Viveiros; Isabel Couto; Leonard Amaral. "Evaluation of forty new phenothiazine derivatives for activity against intrinsic efflux pump systems of reference Escherichia coli, Salmonella enteritidis, Enterococcus faecalis and Staphylococcus aureus strains". In Vivo 25 5 (2011): 719-724. https://research.unl.pt/en/publications/evaluation-of-forty-new-phenothiazine-derivatives-for-activity-against-intrinsic-efflux-pump-systems-of-reference-escherichia-coli-salmonella-enteritidis-enterococcus-faecalis-and-staphylococcus-aure(aa96152c-ac41-4.
- Martins M; Viveiros M; Couto I; Costa SS; Pacheco T; Fanning S; Pagès JM; Amaral L. "Identification of efflux pump-mediated multidrug-resistant bacteria by the ethidium bromide-agar cartwheel method.". In Vivo (2011): http://europepmc.org/abstract/med/21471531.
- Ana Martins; L, Machado; S. Costa; P, Cerca; G. Spengler; Miguel Viveiros; Leonard Amaral. "Role of calcium in the efflux system of Escherichia coli.". International Journal Of Antimicrobial Agents 37 5 (2011): 410-414. https://research.unl.pt/en/publications/role-of-calcium-in-the-efflux-system-of-escherichia-coli(865b70b0-2c27-45e6-95a5-d4660562156d).html.
10.1016/j.ijantimicag.2011.01.010
- P, Cerca; Ana Martins; Isabel Couto; Miguel Viveiros; Leonard Amaral. "Competition between substrates of the efflux pump system of Salmonella enteritidis.". In vivo (Athens, Greece) 25 4 (2011): 597-602. https://research.unl.pt/en/publications/competition-between-substrates-of-the-efflux-pump-system-of-salmonella-enteritidis(bbb3a9aa-0235-416f-8a8a-3cb30de45e45).html.
- Ana Martins; A. Vasas; Miguel Viveiros; J Molnár; J. Hohmann; Leonard Amaral. "Antibacterial properties of compounds isolated from Carpobrotus edulis.". International Journal Of Antimicrobial Agents 37 5 (2011): 438-444. https://research.unl.pt/en/publications/antibacterial-properties-of-compounds-isolated-from-carpobrotus-edulis(ebb51e70-14e4-4fff-be48-5c6b97fb6c2c).html.
10.1016/j.ijantimicag.2011.01.016
- L, Rodrigues; J, Ramos; Isabel Couto; Leonard Amaral; Miguel Viveiros; Rodrigues , Liliana; Ramos, Jorge; et al. "Ethidium bromide transport across Mycobacterium smegmatis cell-wall: correlation with antibiotic resistance.". Bmc Microbiology 11 NA (2011): 35-35. https://research.unl.pt/en/publications/ethidium-bromide-transport-across-mycobacterium-smegmatis-cellwall-correlation-with-antibiotic-resistance(a95c3627-3ddf-441d-b10a-df02f43c68d7).html.
10.1186/1471-2180-11-35
- Leonard Amaral; M Martins; Miguel Viveiros. "Thioridazine: alternative and potentially effective therapy of the XDR-TB patient.". Letters In Drug Design & Discovery 8 2 (2011): 130-132. https://research.unl.pt/en/publications/thioridazine-alternative-and-potentially-effective-therapy-of-the-xdrtb-patient(5e02ba83-14ea-41aa-8114-cf005ef247b0).html.
10.2174/157018011794183860
- Rodrigues, L.; Aínsa, J.A.; Amaral, L.; Viveiros, M.. "Inhibition of drug efflux in mycobacteria with phenothiazines and other putative efflux inhibitors". Recent Patents on Anti-Infective Drug Discovery 6 2 (2011): 118-127. http://www.scopus.com/inward/record.url?eid=2-s2.0-79960065506&partnerID=MN8TOARS.
10.2174/157489111796064579
- Amaral, L.; Cerca, P.; Spengler, G.; MacHado, L.; Martins, A.; Couto, I.; Viveiros, M.; Fanning, S.; Pags, J.-M.. "Ethidium bromide efflux by Salmonella: Modulation by metabolic energy, pH, ions and phenothiazines". International Journal of Antimicrobial Agents 38 2 (2011): 140-145. http://www.scopus.com/inward/record.url?eid=2-s2.0-79959759805&partnerID=MN8TOARS.
10.1016/j.ijantimicag.2011.03.014
- Pascu, M.-L.; Nastasa, V.; Smarandache, A.; Militaru, A.; Martins, A.; Viveiros, M.; Boni, M.; et al. "Direct modification of bioactive phenothiazines by exposure to laser radiation". Recent Patents on Anti-Infective Drug Discovery 6 2 (2011): 147-157. http://www.scopus.com/inward/record.url?eid=2-s2.0-79959994231&partnerID=MN8TOARS.
10.2174/157489111796064515
- Amara, L.; Viveiros, M.; Molnar, J.; Kristiansen, J.E.. "Effective therapy with the neuroleptic thioridazine as an adjunct to second line of defence drugs, and the potential that thioridazine offers for new patents that cover a variety of ''New Uses''". Recent Patents on Anti-Infective Drug Discovery 6 2 (2011): 84-87. http://www.scopus.com/inward/record.url?eid=2-s2.0-79959996814&partnerID=MN8TOARS.
10.2174/157489111796064542
- Ramalhete, C.; Spengler, G.; Martins, A.; Martins, M.; Viveiros, M.; Mulhovo, S.; Ferreira, M.-J.U.; Amaral, L.. "Inhibition of efflux pumps in meticillin-resistant Staphylococcus aureus and Enterococcus faecalis resistant strains by triterpenoids from Momordica balsamina". International Journal of Antimicrobial Agents 37 1 (2011): 70-74. http://www.scopus.com/inward/record.url?eid=2-s2.0-78650262885&partnerID=MN8TOARS.
10.1016/j.ijantimicag.2010.09.011
- Machado, LisaSantos. "The Inhibitory Activity of Synthetic Compounds and Ions Against Transporters of Multi-drug Resistant Bacteria". Universidade NOVA de Lisboa (Portugal) (2011): https://publons.com/wos-op/publon/64719086/.
- Kristiansen JE; Thomsen VF; Martins A; Viveiros M; Amaral L. "Non-antibiotics reverse resistance of bacteria to antibiotics.". In Vivo (2010): http://europepmc.org/abstract/med/20952744.
- A. Martins; A. Vasas; Z. S. Schelz; Miguel Viveiros; Joseph Molnar; J. Hohmann; L. Amaral. "Constituents of Carpobrotus edulis Inhibit P-Glycoprotein of MDR1-transfected Mouse Lymphoma Cells". Anticancer Research 30 3 (2010): 829-835. https://research.unl.pt/en/publications/constituents-of-carpobrotus-edulis-inhibit-pglycoprotein-of-mdr1transfected-mouse-lymphoma-cells(7a37d487-12e5-497a-a2c2-3dbae69ac091).html.
- Leonard Amaral; Miguel Viveiros. "Biological Activity of Hydantoin Derivatives on P-Glycoprotein (ABCB1) of Mouse Lymphoma Cells.". Anticancer Research 30 12 (2010): 4867-4871. https://research.unl.pt/en/publications/biological-activity-of-hydantoin-derivatives-on-pglycoprotein-abcb1-of-mouse-lymphoma-cells(f1af5fe1-fd80-4a7a-9b80-9637a5c7d7f6).html.
- Leonard Amaral; A, Martins; J, Molnár; JE, Kristiansen; M, Martins; Miguel Viveiros; L, Rodrigues; et al. "Thioridazine cures extensively drug-resistant tuberculosis (XDR-TB) and the need for global trials is now!". International Journal Of Antimicrobial Agents 35 6 (2010): 524-6. https://research.unl.pt/en/publications/thioridazine-cures-extensively-drugresistant-tuberculosis-xdrtb-and-the-need-for-global-trials-is-now(74bcade5-7cd5-4922-b3fc-97944065d5c6).html.
10.1016/j.ijantimicag.2009.12.019
- J, Chevalier; A, Mahamoud; M, Baitiche; E, Adam; Miguel Viveiros; A, Smarandache; A, Militaru; et al. "Quinazoline derivatives are efficient chemosensitizers of antibiotic activity in Enterobacter aerogenes, Klebsiella pneumoniae and Pseudomonas aeruginosa resistant strains.". International Journal Of Antimicrobial Agents 36 2 (2010): 164-168. https://research.unl.pt/en/publications/quinazoline-derivatives-are-efficient-chemosensitizers-of-antibiotic-activity-in-enterobacter-aerogenes-klebsiella-pneumoniae-and-pseudomonas-aeruginosa-resistant-strains(fc26a076-2106-4cbf-81f1-83515193e57b).html.
10.1016/j.ijantimicag.2010.03.027
- Leonard Amaral; Isabel Couto; Miguel Viveiros. "Phenothiazines, bacterial efflux pumps and targeting the macrophage for enhanced killing of intracellular XDRTB.". In Vivo 24 4 (2010): 409-24. https://research.unl.pt/en/publications/phenothiazines-bacterial-efflux-pumps-and-targeting-the-macrophage-for-enhanced-killing-of-intracellular-xdrtb(4dceb97c-78b6-4568-8a08-17eee159d483).html.
- Miguel Viveiros; M Martins; Isabel Couto; L Rodrigues; Diana Machado; I, Portugal; Leonard Amaral. "Molecular tools for rapid identification and novel effective therapy against MDRTB/XDRTB infections.". Expert Review Of Anti-Infective Therapy 8 4 (2010): 465-80. https://research.unl.pt/en/publications/molecular-tools-for-rapid-identification-and-novel-effective-therapy-against-mdrtbxdrtb-infections(1a6357bd-6bd7-42d9-8971-fef672c368aa).html.
10.1586/eri.10.20
- Isabel Couto; Diana Machado; Miguel Viveiros; L, Rodrigues; Leonard Amaral. "Identification of nontuberculous mycobacteria in clinical samples using molecular methods: a 3-year study.". Clinical Microbiology and Infection 16 8 (2010): 1161-4. https://research.unl.pt/en/publications/identification-of-nontuberculous-mycobacteria-in-clinical-samples-using-molecular-methods-a-3year-study(9f3654d8-6af6-40c2-a10d-5885a74e643f).html.
10.1111/j.1469-0691.2009.03076.x
- Leonard Amaral; Isabel Couto; Miguel Viveiros. "Physiological characterisation of the efflux pump system of antibiotic-susceptible and multidrug-resistant Enterobacter aerogenes.". International Journal Of Antimicrobial Agents 36 4 (2010): 313-318. https://research.unl.pt/en/publications/physiological-characterisation-of-the-efflux-pump-system-of-antibioticsusceptible-and-multidrugresistant-enterobacter-aerogenes(476a7457-e521-4833-a63d-da9839b03b42).html.
10.1016/j.ijantimicag.2010.06.036
- Isabel Couto; Miguel Viveiros; P. V. Baptista. "Au-nanoprobes for detection of SNPs associated with antibiotic resistance in Mycobacterium tuberculosis.". Nanotechnology 21 41 (2010): 415101-415101. https://research.unl.pt/en/publications/aunanoprobes-for-detection-of-snps-associated-with-antibiotic-resistance-in-mycobacterium-tuberculosis(410472c4-7c42-4661-8721-34d5c9f1a879).html.
10.1088/0957-4484/21/41/415101
- Sofia Santos Costa; E, Ntokou; A, Martins; Miguel Viveiros; S, Pouranas; Leonard Amaral; Isabel Couto. "Identification of the plasmid-encoded qacA efflux pump gene in meticillin-resistant Staphylococcus aureus (MRSA) strain HPV107, a representative of the MRSA Iberian clone.". International Journal Of Antimicrobial Agents 36 6 (2010): 557-61. https://research.unl.pt/en/publications/identification-of-the-plasmidencoded-qaca-efflux-pump-gene-in-meticillinresistant-staphylococcus-aureus-mrsa-strain-hpv107-a-representative-of-the-mrsa-iberian-clone(3b723a33-fb4e-40ee-b1b8-dab03bbc7b78).html.
10.1016/j.ijantimicag.2010.08.006
- Miguel Viveiros; Liliana Rodrigues; Marta Martins; Isabel Couto; Gabriella Spengler; Ana Martins; Leonard Amaral. "Evaluation of efflux activity of bacteria by a semi-automated fluorometric system". Methods In Molecular Biology (Clifton, N.J.) 642 (2010): 159-72. https://research.unl.pt/en/publications/evaluation-of-efflux-activity-of-bacteria-by-a-semiautomated-fluorometric-system(3e302ca5-1108-4948-b7c4-16c82c7f9ad4).html.
10.1007/978-1-60327-279-7_12
- Marta Martins; Miguel Viveiros; Diane Ordway; Jette E. Kristiansen; Joseph Molnar; Leonard Amaral. "Reserpine, ouabain and the calcium channel blocker verapamil, cause intracellular killing of Staphylococcus aureus". Research Journal of Microbiology 5 6 (2010): 490-496. https://research.unl.pt/en/publications/reserpine-ouabain-and-the-calcium-channel-blocker-verapamil-cause-intracellular-killing-of-staphylococcus-aureus(29ea7e83-8af4-4d2a-8b37-0876c0f8aac4).html.
10.3923/jm.2006.203.209
- Martins, M.; Couto, I.; Viveiros, M.; Amaral, L.. "Identification of efflux-mediated multi-drug resistance in bacterial clinical isolates by two simple methods.". Methods in molecular biology (Clifton, N.J.) 642 (2010): 143-157. http://www.scopus.com/inward/record.url?eid=2-s2.0-77954672260&partnerID=MN8TOARS.
10.1007/978-1-60327-279-7_11
- Costa, Susana Cristina Nunes Santos Nunes Santos; COSTA, Susana; COSTA, Susana Cristina Nunes Santos. "Caracterização Preliminar da Bioenergética do Efluxo Pelo Sistema Acrab-tolc em Escherichia Coli". Universidade NOVA de Lisboa (Portugal) (2010): https://publons.com/wos-op/publon/64719085/.
- Martins A; Spengler G; Rodrigues L; Viveiros M; Ramos J; Martins M; Couto I; et al. "pH Modulation of efflux pump activity of multi-drug resistant Escherichia coli: protection during its passage and eventual colonization of the colon.". PloS one (2009): http://europepmc.org/abstract/med/19684858.
10.1371/journal.pone.0006656
- Spengler G; Viveiros M; Martins M; Rodrigues L; Martins A; Molnar J; Couto I; Amaral L. "Demonstration of the activity of P-glycoprotein by a semi-automated fluorometric method.". Anticancer research (2009): http://europepmc.org/abstract/med/19528478.
- Gabriella Spengler; Ana Martins; Zsuzsanna Schelz; Liliana Rodrigues; Lone Aagaard; Marta Martins; Sofia Santos Costa; et al. "Characterization of intrinsic efflux activity of Enterococcus faecalis ATCC29212 by a semi-automated ethidium bromide method". In Vivo 23 1 (2009): 81-7. https://research.unl.pt/en/publications/characterization-of-intrinsic-efflux-activity-of-enterococcus-faecalis-atcc29212-by-a-semiautomated-ethidium-bromide-method(c61939f9-dbe3-4718-8929-fb0f970be727).html.
- Leonard Amaral; Miguel Viveiros; Isabel Couto. "An AcrAB-mediated multidrug-resistant phenotype is maintained following restoration of wild-type activities by efflux pump genes and their regulators". International Journal Of Antimicrobial Agents 34 6 (2009): 602-604. https://research.unl.pt/en/publications/an-acrabmediated-multidrugresistant-phenotype-is-maintained-following-restoration-of-wildtype-activities-by-efflux-pump-genes-and-their-regulators(f5824dcd-c5b1-46eb-af6c-e2eb636ad524).html.
10.1016/j.ijantimicag.2009.06.029
- Leonard Amaral; Miguel Viveiros; Isabel Couto. "Fluorometric determination of ethidium bromide efflux kinetics in Escherichia coli.". Journal Of Biological Engineering 3 NA (2009): 18-18. https://research.unl.pt/en/publications/fluorometric-determination-of-ethidium-bromide-efflux-kinetics-in-escherichia-coli(9a66e485-80b4-4a1b-aec4-6bfa9060b9ba).html.
10.1186/1754-1611-3-18
- Leonard Amaral; Miguel Viveiros; Isabel Couto. "The role of efflux pumps in macrolide resistance in Mycobacterium avium complex". International Journal Of Antimicrobial Agents 34 6 (2009): 529-533. https://research.unl.pt/en/publications/the-role-of-efflux-pumps-in-macrolide-resistance-in-mycobacterium-avium-complex(0924160f-b4d4-41ed-868d-be68bb03c3e6).html.
10.1016/j.ijantimicag.2009.07.010
- Miguel Viveiros; Leonard Amaral; Isabel Couto. "SILA 421, an inhibitor of efflux pumps of cancer cells, enhances the killing of intracellular extensively drug-resistant tuberculosis (XDR-TB)". International Journal Of Antimicrobial Agents 33 5 (2009): 479-482. https://research.unl.pt/en/publications/sila-421-an-inhibitor-of-efflux-pumps-of-cancer-cells-enhances-the-killing-of-intracellular-extensively-drugresistant-tuberculosis-xdrtb(bbfd06a7-9363-48df-b32f-59f8a2490489).html.
10.1016/j.ijantimicag.2008.10.028
- Miguel Viveiros; Leonard Amaral; Isabel Couto. "Targeting human macrophages for enhanced killing of intracellular XDR-TB and MDR-TB.". International Journal Of Tuberculosis And Lung Disease 13 5 (2009): 569-73. https://research.unl.pt/en/publications/targeting-human-macrophages-for-enhanced-killing-of-intracellular-xdrtb-and-mdrtb(0abde695-e879-4be9-8b3f-ce2ddcd65080).html.
- Spengler, G.; Ramalhete, C.; Martins, M.; Martins, A.; Serly, J.; Viveiros, M.; Molnár, J.; et al. "Evaluation of cucurbitane-type triterpenoids from Momordica balsamina on P-glycoprotein (ABCB1) by flow cytometry and real-time fluorometry". Anticancer Research 29 10 (2009): 3989-3993. http://www.scopus.com/inward/record.url?eid=2-s2.0-71949083688&partnerID=MN8TOARS.
- Marta Martins; Miguel Viveiros; Leonard Amaral. "The TB laboratory of the future". Future Microbiology 3 2 (2008): 135-144. https://research.unl.pt/en/publications/the-tb-laboratory-of-the-future(3a9c3aef-56ef-4473-b0dd-f53a8016e980).html.
10.2217/17460913.3.2.135
- Marta Martins; Miguel Viveiros; Leonard Amaral. "Inhibitors of Ca2+ and K+ transport enhance intracellular killing of M-tuberculosis by non-killing macrophages". In Vivo 22 1 (2008): 69-75. https://research.unl.pt/en/publications/inhibitors-of-ca2-and-k-transport-enhance-intracellular-killing-of-mtuberculosis-by-nonkilling-macrophages(1acf472d-2e82-4f36-8187-7fab48b71422).html.
- Viveiros, M; Martins, A; Paixao, L; Rodrigues, L; Martins, M; Couto, I; Faehnrich, E; Kern, WV; Amaral, L. "Demonstration of intrinsic efflux activity of Escherichia coli K-12 AG100 by an automated ethidium bromide method". INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2008):
10.1016/j.ijantimicag.2007.12.015
- Martins, M.; Viveiros, M.; Amaral, L.. "Enhanced killing of intracellular pathogenic bacteria by phenothiazines and the role of K+ efflux pumps of the bacterium and the killing macrophage". Anti-Infective Agents in Medicinal Chemistry 7 1 (2008): 63-72. http://www.scopus.com/inward/record.url?eid=2-s2.0-41149156855&partnerID=MN8TOARS.
10.2174/187152108783329807
- Martins, M.; Dastidar, S.G.; Fanning, S.; Kristiansen, J.E.; Molnar, J.; Pagès, J.-M.; Schelz, Z.; et al. "Potential role of non-antibiotics (helper compounds) in the treatment of multidrug-resistant Gram-negative infections: mechanisms for their direct and indirect activities". International Journal of Antimicrobial Agents 31 3 (2008): 198-208. http://www.scopus.com/inward/record.url?eid=2-s2.0-39149121434&partnerID=MN8TOARS.
10.1016/j.ijantimicag.2007.10.025
- Rodrigues, L.; Wagner, D.; Viveiros, M.; Sampaio, D.; Couto, I.; Vavra, M.; Kern, W.V.; Amaral, L.. "Thioridazine and chlorpromazine inhibition of ethidium bromide efflux in Mycobacterium avium and Mycobacterium smegmatis". Journal of Antimicrobial Chemotherapy 61 5 (2008): 1076-1082. http://www.scopus.com/inward/record.url?eid=2-s2.0-42149168442&partnerID=MN8TOARS.
10.1093/jac/dkn070
- Amaral, L.; Martins, M.; Viveiros, M.; Molnar, J.; Kristiansen, J.E.. "Promising therapy of XDR-TB/MDR-TB with thioridazine an inhibitor of bacterial efflux pumps". Current Drug Targets 9 9 (2008): 816-819. http://www.scopus.com/inward/record.url?eid=2-s2.0-52449123326&partnerID=MN8TOARS.
10.2174/138945008785747798
- Couto, I.; Costa, S.S.; Viveiros, M.; Martins, M.; Amaral, L.; <u>Couto, Isabel</u>; <b>Costa, Sofia Santos</b>; et al. "Efflux-mediated response of Staphylococcus aureus exposed to ethidium bromide". Journal of Antimicrobial Chemotherapy 62 3 (2008): 504-513. http://www.scopus.com/inward/record.url?eid=2-s2.0-49649085104&partnerID=MN8TOARS.
10.1093/jac/dkn217
- Marta Martins; Miguel Viveiros; Jette E. Kristiansen; Joseph Molnar; Leonard Amaral. "The curative activity of thioridazine on mice infected with Mycobacterium tuberculosis". In Vivo 21 5 (2007): 771-776. https://research.unl.pt/en/publications/the-curative-activity-of-thioridazine-on-mice-infected-with-mycobacterium-tuberculosis(ffeaa1b8-aaa8-4821-9cb4-a2eae377ae60).html.
- Noélia Duarte; Maria José U Ferreira; Marta Martins; Miguel Viveiros; Leonard Amaral. "Antibacterial activity of ergosterol peroxide against Mycobacterium tuberculosis". Phytotherapy Research 21 7 (2007): 601-604. https://research.unl.pt/en/publications/antibacterial-activity-of-ergosterol-peroxide-against-mycobacterium-tuberculosis(fc094880-9fe3-43d2-a9a0-d8558361b217).html.
10.1002/ptr.2119
- Zsuzsanna Schelz; Marta Martins; Ana Martins; Miguel Viveiros; Joseph Molnar; Leonard Amaral. "Elimination of plasmids by SILA compounds that inhibit efflux pumps of bacteria and cancer cells". In Vivo 21 4 (2007): 635-640. https://research.unl.pt/en/publications/elimination-of-plasmids-by-sila-compounds-that-inhibit-efflux-pumps-of-bacteria-and-cancer-cells(dd5b8258-e90a-423e-8ca3-e15dffd8e0ca).html.
- Amaral, L.; Engi, H.; Viveiros, M.; Molnar, J.. "Comparison of multidrug resistant efflux pumps of cancer and bacterial cells with respect to the same inhibitory agents". In Vivo 21 2 (2007): 237-244. http://www.scopus.com/inward/record.url?eid=2-s2.0-34047222991&partnerID=MN8TOARS.
- Amaral, L.; Martins, M.; Viveiros, M.. "Enhanced killing of intracellular multidrug-resistant Mycobacterium tuberculosis by compounds that affect the activity of efflux pumps". Journal of Antimicrobial Chemotherapy 59 6 (2007): 1237-1246. http://www.scopus.com/inward/record.url?eid=2-s2.0-34447542162&partnerID=MN8TOARS.
10.1093/jac/dkl500
- Martins, M.; Schelz, Z.; Martins, A.; Molnar, J.; Hajös, G.; Riedl, Z.; Viveiros, M.; et al. "In vitro and ex vivo activity of thioridazine derivatives against Mycobacterium tuberculosis". International Journal of Antimicrobial Agents 29 3 (2007): 338-340. http://www.scopus.com/inward/record.url?eid=2-s2.0-33846969173&partnerID=MN8TOARS.
10.1016/j.ijantimicag.2006.10.013
- Amaral, L.; Martins, M.; Viveiros, M.. "Phenothiazines as anti-multi-drug resistant tubercular agents". Infectious Disorders - Drug Targets 7 3 (2007): 257-265. http://www.scopus.com/inward/record.url?eid=2-s2.0-35649009444&partnerID=MN8TOARS.
10.2174/187152607782110022
- Martins, A.; Couto, I.; Aagaard, L.; Martins, M.; Viveiros, M.; Kristiansen, J.E.; Amaral, L.. "Prolonged exposure of methicillin-resistant Staphylococcus aureus (MRSA) COL strain to increasing concentrations of oxacillin results in a multidrug-resistant phenotype". International Journal of Antimicrobial Agents 29 3 (2007): 302-305. http://www.scopus.com/inward/record.url?eid=2-s2.0-33846939351&partnerID=MN8TOARS.
10.1016/j.ijantimicag.2006.10.012
- Duarte, Noelia; Ferreira, Maria-Jose U.; Martins, Marta; Viveiros, Miguel; Amaral, Leonard. "Antibacterial activity of ergosterol peroxide against Mycobacterium tuberculosis". (2007): http://hdl.handle.net/10451/21440.
http://dx.doi.org/10.1002/ptr.2119
- Viveiros, Miguel; Dupont, Myrielle; Rodrigues, Liliana; Couto, Isabel; Davin-Regli, Anne; Martins, Marta; Pagès, Jean Marie; et al. "Antibiotic stress, genetic response and altered permeability of E. coli". PLOS ONE (2007): http://hdl.handle.net/10362/117209.
https://doi.org/10.1371/journal.pone.0000365
- Martins M; Santos B; Martins A; Viveiros M; Couto I; Cruz A; Pagès JM; et al. "An instrument-free method for the demonstration of efflux pump activity of bacteria.". In vivo (Athens, Greece) (2006): http://europepmc.org/abstract/med/17091774.
- Kristina Wolfart; Gabriella Spengler; Masami Kawase; Noboru Motohashi; Joseph Molnr; Miguel Viveiros; Leonard Amaral. "Synergistic interaction between proton pump inhibitors and resistance modifiers". In Vivo 20 3 (2006): 367-372. https://research.unl.pt/en/publications/synergistic-interaction-between-proton-pump-inhibitors-and-resistance-modifiers(740ea607-96a5-4fec-a406-7b990ba58100).html.
- Malthe M. Kristiansen; Clara Leandro; Diane Ordway; Marta Martins; Miguel Viveiros; Teresa Pacheco; Joseph Molnar; Jette E. Kristiansen; Leonard Amaral. "Thioridazine reduces resistance of methicillin-resistant Staphylococcus aureus by inhibiting a reserpine-sensitive efflux pump". In Vivo 20 3 (2006): 361-366. https://research.unl.pt/en/publications/thioridazine-reduces-resistance-of-methicillinresistant-staphylococcus-aureus-by-inhibiting-a-reserpinesensitive-efflux-pump(890b5163-3167-417a-a31f-a5a85c93cbe7).html.
- Amaral, L.; Viveiros, M.; Kristiansen, J.E.. ""Non-antibiotics": Alternative therapy for the management of MDRTB and MRSA in economically disadvantaged countries". Current Drug Targets 7 7 (2006): 887-891. http://www.scopus.com/inward/record.url?eid=2-s2.0-33745738994&partnerID=MN8TOARS.
10.2174/138945006777709539
- Miguel Viveiros; Ana R. Jesus; Mafalda Brito; Clara Leandro; Marta Martins; Diane Ordway; Ana Maria Molnar; Joseph Molnar; Leonard Amaral. "Inducement and reversal of tetracycline resistance in Escherichia coli K-12 and expression of proton gradient-dependent multidrug efflux pump genes". Antimicrobial Agents and Chemotherapy -Journal- 49 8 (2005): 3578-3582. https://research.unl.pt/en/publications/inducement-and-reversal-of-tetracycline-resistance-in-escherichia-coli-k12-and-expression-of-proton-gradientdependent-multidrug-efflux-pump-genes(d09c3293-07b6-4d19-8115-6b4c2d8589a5).html.
10.1128/aac.49.8.3578-3582.2005
- Miguel Viveiros; Marta Martins; Isabel Couto; Jette E. Kristiansen; Joseph Molnar; Leonard Amaral. "The in vitro activity of phenothiazines against Mycobacterium avium". In Vivo 19 4 (2005): 733-736. https://research.unl.pt/en/publications/the-in-vitro-activity-of-phenothiazines-against-mycobacterium-avium(fbdec778-4c28-4150-8719-f1d9b476b329).html.
- Diane J. Ordway; Miguel Viveiros; Fernando A. Ventura; Ian M. Orme; Hazel M. Dockrell; Leonard Amaral. "Exogenous Re-infection by Multiple Exposures to Mycobacterium tuberculosis Contributes to Subsequent Development of Active Tuberculosis". American Journal of Immunology 1 1 (2005): 42-47. http://dx.doi.org/10.3844/ajisp.2005.42.47.
10.3844/ajisp.2005.42.47
- Marta Martins; Diane Ordway; Malthe M. Kristiansen; Miguel Viveiros; Clara Leandro; Joseph Molnar; Leonard Amaral. "Inhibition of the Carpobrotus edulis methanol extract on the growth of phagocytosed multidrug-resistant Mycobacterium tuberculosis and methicillin-resistant Staphylococcus aureus". Fitoterapia 76 1 (2005): 96-99. https://research.unl.pt/en/publications/inhibition-of-the-carpobrotus-edulis-methanol-extract-on-the-growth-of-phagocytosed-multidrugresistant-mycobacterium-tuberculosis-and-methicillinresistant-staphylococcus-aureus(3b85af21-61d8-4375-8c9c-83e5cf5bdbca)..
10.1016/j.fitote.2004.09.020
- Viveiros, M; Leandro, C; Rodrigues, L; Almeida, J; Bettencourt, R; Couto, I; Carrilho, L; et al. "Direct application of the INNO-LiPA Rif.TB line-probe assay for rapid identification of Mycobacterium tuberculosis complex strains and detection of rifampin resistance in 360 smear-positive respiratory specimens from an area of high incidence of multidrug-resistant tuberculosis". JOURNAL OF CLINICAL MICROBIOLOGY (2005):
10.1128/jcm.43.9.4880-4884.2005
- Ordway, DJ; Pinto, L; Costa, L; Martins, M; Leandro, C; Viveiros, M; Amaral, L; et al. "Gamma delta T cell responses associated with the development of tuberculosis in health care workers". FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY (2005):
10.1016/j.femsim.2004.09.005
- Marta Martins; Wilfrid Bleiss; Anorte Marko; Diane Ordway; Miguel Viveiros; Clara Leandro; Teresa Pacheco; et al. "Clinical concentrations of thioridazine enhance the killing of intracellular methicillin-resistant Staphylococcus aureus". In Vivo 18 6 (2004): 787-794. https://research.unl.pt/en/publications/clinical-concentrations-of-thioridazine-enhance-the-killing-of-intracellular-methicillinresistant-staphylococcus-aureus(aa321791-8547-499f-b3e4-61f0edc19608).html.
- Amaral L; Viveiros M; Molnar J. "Antimicrobial activity of phenothiazines.". In vivo (Athens, Greece) (2004): http://europepmc.org/abstract/med/15646813.
- Malthe M. Kristiansen; Clara Leandro; Diane Ordway; Marta Martins; Miguel Viveiros; Teresa Pacheco; Jette E. Kristiansen; Leonard Amaral. "Phenothiazines alter resistance of methicillin-resistant strains of Staphylococcus aureus (MRSA) to oxacillin in vitro". International Journal Of Antimicrobial Agents 22 3 (2003): 250-253. https://research.unl.pt/en/publications/phenothiazines-alter-resistance-of-methicillinresistant-strains-of-staphylococcus-aureus-mrsa-to-oxacillin-in-vitro(580a0a3f-9b63-46a4-96da-d37f37a1b599).html.
10.1016/s0924-8579(03)00200-0
- Diane Ordway; Miguel Viveiros; Clara Leandro; Rosário Bettencourt; Josefina Almeida; Marta Martins; Jette E. Kristiansen; Joseph Molnar; Leonard Amaral. "Clinical concentrations of thioridazine kill intracellular multidrug-resistant Mycobacterium tuberculosis". Antimicrobial Agents and Chemotherapy -Journal- 47 3 (2003): 917-922. https://research.unl.pt/en/publications/clinical-concentrations-of-thioridazine-kill-intracellular-multidrugresistant-mycobacterium-tuberculosis(74b76ec6-a5d5-4967-9a8e-b2cbf8729cdb).html.
10.1128/aac.47.3.917-922.2003
- Ordway, D; Hohmann, J; Viveiros, M; Viveiros, A; Molnar, J; Leandro, C; Arroz, MJ; Gracio, MA; Amaral, L. "Carpobrotus edulis methanol extract inhibits the MDR efflux pumps, enhances killing of phagocytosed S-aureus and promotes immune modulation". PHYTOTHERAPY RESEARCH (2003):
10.1002/ptr.1314
- Viveiros, M; Leandro, C; Amaral, L. "Mycobacterial efflux pumps and chemotherapeutic implications". INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2003):
10.1016/s0924-8579(03)00208-5
- Grácio, M.A.; Dos Santos Grácio, A.J.; Viveiros, M.; Amaral, L.. "Since phenothiazines alter antibiotic susceptibility of microorganisms by inhibiting efflux pumps, are these agents useful for evaluating similar pumps in phenothiazine-sensitive parasites?". International Journal of Antimicrobial Agents 22 3 (2003): 347-351. http://www.scopus.com/inward/record.url?eid=2-s2.0-0042834382&partnerID=MN8TOARS.
10.1016/s0924-8579(03)00204-8
- Diane Ordway; Miguel Viveiros; Clara Leandro; Maria Jorge Arroz; Joseph Molnar; Jette E. Kristiansen; Leonard Amaral. "Chlorpromazine has intracellular killing activity against phagocytosed Staphylococcus aureus at clinical concentrations". Journal of Infection and Chemotherapy 8 3 (2002): 227-231. https://research.unl.pt/en/publications/chlorpromazine-has-intracellular-killing-activity-against-phagocytosed-staphylococcus-aureus-at-clinical-concentrations(20f626b7-be04-42bf-bc20-d9de9b2a9909).html.
10.1007/s10156-002-0188-4
- Ordway, D; Viveiros, M; Leandro, C; Arroz, MJ; Amaral, L. "Intracellular activity of clinical concentrations of phenothiazines including thioridiazine against phagocytosed Staphylococcus aureus". INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2002):
10.1016/S0924-8579(02)00110-3
- Viveiros, M.; Portugal, I.; Bettencourt, R.; Victor, T.C.; Jordaan, A.M.; Leandro, C.; Ordway, D.; Amaral, L.. "Isoniazid-induced transient high-level resistance in Mycobacterium tuberculosis". Antimicrobial Agents and Chemotherapy 46 9 (2002): 2804-2810. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036719989&partnerID=MN8TOARS.
10.1128/AAC.46.9.2804-2810.2002
- Amaral L; Kristiansen JE; Viveiros M; Atouguia J. "Activity of phenothiazines against antibiotic-resistant Mycobacterium tuberculosis: a review supporting further studies that may elucidate the potential use of thioridazine as anti-tuberculosis therapy.". The Journal of antimicrobial chemotherapy (2001): http://europepmc.org/abstract/med/11328759.
10.1093/jac/47.5.505
- Miguel Viveiros; L Amaral; Viveiros, M; Amaral, L. "Enhancement of antibiotic activity against poly-drug resistant Mycobacterium tuberculosis by phenothiazines". International Journal Of Antimicrobial Agents 17 3 (2001): 225-228. https://research.unl.pt/en/publications/enhancement-of-antibiotic-activity-against-polydrug-resistant-mycobacterium-tuberculosis-by-phenothiazines(421d5e73-626f-4e33-9cce-de92d7ecf848).html.
10.1016/s0924-8579(00)00343-5
- Amaral, L.; Viveiros, M.; Kristiansen, J.E.. "Phenothiazines: Potential alternatives for the management of antibiotic resistant infections of tuberculosis and malaria in developing countries". Tropical Medicine and International Health 6 12 (2001): 1016-1022. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035657318&partnerID=MN8TOARS.
10.1046/j.1365-3156.2001.00804.x
- Miguel Viveiros; Suzana Bosne-David; Leonard Amaral. "Comparative in vitro activity of phenothiazines against multidrug- resistant Mycobacterium tuberculosis". International Journal Of Antimicrobial Agents 16 1 (2000): 69-71. https://research.unl.pt/en/publications/comparative-in-vitro-activity-of-phenothiazines-against-multidrug-resistant-mycobacterium-tuberculosis(3a4d1ea2-8f75-4af9-a2bf-c13eb2c5454b).html.
10.1016/s0924-8579(00)00199-0
- Viveiros, M.; Krubasik, P.; Sandmann, G.; Houssaini-Iraqui, M.. "Structural and functional analysis of the gene cluster encoding carotenoid biosynthesis in Mycobacterium aurum A+". FEMS Microbiology Letters 187 1 (2000): 95-101. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034213794&partnerID=MN8TOARS.
10.1016/S0378-1097(00)00182-8
- Miguel Viveiros; S. Pinheiro; Patrícia Raquel Moreira; Teresa Pacheco; Laura Maria Lourenço Brum da Cruz Martins. "Evaluation of a commercial ligase chain reaction assay for the diagnosis of pulmonary and extra-pulmonary tuberculosis". International Journal of Tuberculosis and Lung Disease 3 6 (1999): 508-514. https://research.unl.pt/en/publications/evaluation-of-a-commercial-ligase-chain-reaction-assay-for-the-diagnosis-of-pulmonary-and-extrapulmonary-tuberculosis(f32adb81-01f8-417d-82ca-555f263437d5).html.
- Portugal I; Covas MJ; Brum L; Viveiros M; Ferrinho P; Moniz-Pereira J; David H. "Outbreak of multiple drug-resistant tuberculosis in Lisbon: detection by restriction fragment length polymorphism analysis.". The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease (1999): http://europepmc.org/abstract/med/10094321.
- Graça Ribeiro; Miguel Viveiros; H. L. David; João V. Costa. "Mycobacteriophage D29 contains an integration system similar to that of the temperate mycobacteriophage L5". Microbiology-Sgm 143 8 (1997): 2701-2708. https://research.unl.pt/en/publications/mycobacteriophage-d29-contains-an-integration-system-similar-to-that-of-the-temperate-mycobacteriophage-l5(9858b247-c6d1-43b9-bbd0-a87dd1f10d8a).html.
10.1099/00221287-143-8-2701
- Emília Prieto; Teresa Pacheco; Miguel Viveiros; Rosário Bettencourt; Laura Brum; Filomena Exposto. "Pesquisa de infecção micobacteriana em hemoculturas de doentes com SIDA, usando o sistema BACTEC 460TB". Revista Portuguesa de Pneumologia 2 6 (1996): 403-407. http://dx.doi.org/10.1016/s0873-2159(15)31178-8.
10.1016/s0873-2159(15)31178-8
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| Artigo em revista (magazine) |
- Correia, T; Viveiros, Miguel; Pedrosa, Jorge. "Disease X and the limits of voluntary multilateralism", The Microbiologist, 2026
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| Capítulo de livro |
- da Silva, PEA; Machado, D; Ramos, D; Couto, I; Von Groll, A; Viveiros, M. "Efflux Pumps in Mycobacteria: Antimicrobial Resistance, Physiological Functions, and Role in Pathogenicity". 2016.
10.1007/978-3-319-39658-3_21
- Miguel Viveiros; Isabel Couto; Joao Inacio. "Diagnóstico Molecular". editado por {Barroso, 182-196. Lidel - Edi{\cc, 2014.
- Miguel Viveiros; Isabel Couto; ML, Rossetti; PA, da Silva. "Otimização, validação e controlo de qualidade de testes moleculares de diagnóstico". editado por {Cunha. Lidel - Edi{\cc, 2014.
- I, Portugal; Miguel Viveiros. "Mycobacterium". 316-331. Lidel - Edi{\cc, 2014.
- Miguel Viveiros; Leonard Amaral; Isabel Couto. "Therapy of the XDR-TB patients with thioridazine - an old drug with new applications.". 232-242. CABI, 2013.
- Miguel Viveiros; Isabel Couto; Leonard Amaral. "Improving on the LJ slope: automated liquid culture.". 34-45. CABI, 2013.
- Leonard Amaral; Ana Martins; Gabriella Spengler; Marta Martins; Liliana Rodrigues; Matthew McCusker; Eleni Ntokou; et al. "Structure, Genetic Regulation, Physiology and function of the acrab-tolc efflux pump of escherichia coli and salmonella". 44-61. CABI Publishing, 2012.
- Leonard Amaral; Séamus Fanning; Gabriella Spengler; L. Rodrigues; C. Iversen; M. Martins; A. Martins; et al. "Genetic regulation, physiology, assessment and inhibition of efflux pumps responsible for multi-drug resistant phenotypes of bacterial pathogens". editado por A Meszaros; G Balogh, 91-116. Nova Science Publishers, Inc., 2012.
- Miguel Viveiros. "Segurança em laboratórios de Microbiologia.". 587-609. Edi{\cc, 2010.
- Miguel Viveiros; Leonard Amaral; Isabel Couto. "One day identification of the md-rtb patient and proposed novel and effective therapy that is supported by extensive research.". 328 p.-328 p.. Nova science publishers, 2009.
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| Livro |
- Armada, A.; Martins, C.; Spengler, G.; Molnar, J.; Amaral, L.; Rodrigues, A.S.; Viveiros, M.. Fluorimetric methods for analysis of permeability, drug transport kinetics, and inhibition of the ABCB1 membrane transporter. 2016.
10.1007/978-1-4939-3347-1_7
- Costa, P.; Couto, I.; Viveiros, M.; Inácio, J.. Nested and multiplex real-time PCR using dual-labeled probes: Detecting and discriminating Mycobacterium tuberculosis complex members in cultures and animal tissues. 2014.
10.1007/978-1-4939-2004-4_9
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| Poster em conferência |
- Pereira, I.; Gustavo, Cassiano,; Viveiros, Miguel; Costa, Sofia Santos; Rodrigues, Liliana. "Drug repurposing to counter efflux-driven antimicrobial resistance in Neisseria gonorrhoeae". Trabalho apresentado em ESCMID Global, 2026.
- <u>Andrade, Mariana</u>; <b>Neves, Joana</b>; Rita, Pedro; Nunes, Matilde; Seabra, Sofia G.; Armada, Ana; Viveiros, Miguel; et al. Autor correspondente: Costa, Sofia S.. "Repurposing drugs to inhibit efflux and biofilm formation in antimicrobial-resistant Gram-positive pathogens". Trabalho apresentado em ESCMID Global 2026, 2026.
- Andrade, Mariana; Neves, Joana; Hanke, Dennis; Feßler, Andrea T.; Schwarz, Stefan; Sofia G. Seabra; Viveiros, Miguel; et al. "In vivo efficacy and target elucidation of new candidate drugs for repurposing against biofilm-producing antimicrobial-resistant staphylococci". Trabalho apresentado em XVI Jornadas Cientificas do IHMT, 2025.
- Pereira, I.; Pina, André; Vitor, Inês; Santos, Beatriz; Henriques, Ana; Pereira, Filomena; Couto, Isabel; et al. "Exploring new drugs for Neisseria gonorrhoeae through in silico repurposing targeting efflux mechanisms". Trabalho apresentado em Microbiotec'25, 2025.
- Ramos, Jorge; Alexandra Santos; Couto, Isabel; Rodrigues, L; Sofia Santos Costa; SS Costa; S Santos Costa; Sofia G. Seabra; Viveiros, Miguel; Ana Paula Arez. "Biobanking for Antimicrobial Resistance Surveillance: The Strategic Role of the BIOTROP Infrastructure (IHMT NOVA)". Trabalho apresentado em Congress of Microbiology and Biotechnology 2025 (Microbiotec’25), 2025.
- <u>Marinheiro A</u>; <b>Costa SS</b>; Viveiros M; Rodrigues L. "Efflux pump contribution to antimicrobial resistance in <I>Neisseria gonorrhoeae</I>: phenotypic and molecular characterization.". Trabalho apresentado em National Congress of Microbiology and Biotechnology 2025 (Microbiotec’25), 2025.
- <u>Pereira I</u>; Pina A; Santos B; Vítor I; Henriques A; Pereira F; Couto I; et al. "Exploring new drugs for <I>Neisseria gonorrhoeae</I> through <I>in silico</I> repurposing targeting membrane transport and energy metabolism". Trabalho apresentado em National Congress of Microbiology and Biotechnology (MicroBiotec25), 2025.
- <u>Martinho D</u>; Ferreira C; Melo-Cristino J; Viveiros M; <b>Costa SS</b>; Couto I. "Walking towards the characterization of <I>Staphylococcus haemolyticus</I> and <I>Staphylococcus hominis</I> effluxome". Trabalho apresentado em National Congress of Microbiology and Biotechnology 2025 (Microbiotec’25), 2025.
- Andrade, Mariana; Neves, Joana; Marques, Joana; Rita, Pedro; Armada A.; Sofia G. Seabra; Cortes, Sofia; et al. "Galleria mellonella Research Hub: a sustainable in vivo infection model at GHTM/IHMT-NOVA". Trabalho apresentado em Congress of Microbiology and Biotechnology 2025, 2025.
- Andrade, Mariana; Neves, Joana; Nunes, Matilde; Sofia G. Seabra; Armada A.; Viveiros, Miguel; Rodrigues, L; Couto, Isabel; Sofia Santos Costa; SS Costa; S Santos Costa. "Targeting efflux and biofilms: new candidate drugs for repurposing against antimicrobial-resistant Staphylococcus aureus and Staphylococcus epidermidis". Trabalho apresentado em Congress of Microbiology and Biotechnology 2025, 2025.
- Rita, Pedro; Andrade, Mariana; Viveiros, Miguel; Rodrigues, L; Couto, Isabel; Sofia Santos Costa; SS Costa; S Santos Costa. "Applying a drug repurposing strategy to identify new efflux inhibitors and antibiofilm agents for Enterococcus faecalis and Pseudomonas aeruginosa". Trabalho apresentado em Congress of Microbiology and Biotechnology 2025, 2025.
- Mariana Pinto; Skouridou, Vasso; Ana Tavares; Mayreli Ortiz; Miriam Jauset-Rubio; Viveiros, Miguel; Ana Paula Arez; Ciara K. O' Sullivan; Medeiros, MM. "Isothermal Nucleic Acid Amplification with Recombinase Polymerase for Rapid Detection of Drug Resistance in Plasmodium Parasites: a Feasible Point-of-Care Technology". Trabalho apresentado em Encontro Ciência 2025, 2025.
- Matos, Sofia; Diana Machado; Clark, Taane; Couto, Isabel; Viveiros, Miguel; Portugal, Isabel; Perdigão, João. "Global Genomic Landscape of Mycobacterium avium: Diversity, Transmission Dynamics, and Drug Resistance Mechanisms". Trabalho apresentado em European Society of Mycobacteriology (ESM) 45th Annual Congress, 2025.
- <u>Andrade, Mariana</u>; Neves, Joana; Bento, Maria; Marques, Joana; Seabra, Sofia G.; Viveiros, Miguel; Rodrigues, Liliana; et al. "Evaluation of candidate drugs for repurposing in a <i>Galleria mellonella</i> staphylococcal infection model.". Trabalho apresentado em Accepted for poster presentation at ESCMID Global 2025 - Congress of the European Society of¿ Clinical Microbiology and Infectious Diseases, 2025.
- Andrade, Mariana; <b>Neves, Joana</b>; Rita, Pedro; Nunes, Matilde; Seabra, Sofia G.; Armada, Ana; Viveiros, Miguel; et al. "<i>In vitro</i> and </i>in vivo</i> evaluation of new candidate drugs for repurposing as efflux inhibitors and antibiofilm agents against antimicrobial-resistant Gram-positive pathogens". Trabalho apresentado em 2025 Multi-Drug Efflux Systems Gordon Research Conference (accepted), 2025.
- Andrade, Mariana; <b>Neves, Joana</b>; Rita, Pedro; Nunes, Matilde; Seabra, Sofia G.; Armada, Ana; Viveiros, Miguel; et al. "New candidate drugs for repurposing as efflux inhibitors and antibiofilm agents against antimicrobial-resistant <i>Staphylococcus aureus</i>, <i>Staphylococcus epidermidis</i> and <i>Enterococcus faecalis</i>". Trabalho apresentado em 10th Symposium on Antimicrobial Resistance in Animals and the Environment (submitted), 2025.
- <u>Andrade, Mariana</u>; Neves, Joana; Marques, Joana; Armada, Ana; Rodrigues, Liliana; Viveiros, Miguel; Silveira, Henrique; Couto, Isabel; <b>Costa, Sofia Santos </b>. "<i>Galleria mellonella</i> research hub: a new in vivo infection model at GHTM/IHMT-NOVA.". Trabalho apresentado em NOVAHealth VII International Conference “Tackling Pandemics: Strategies for Prevention, Preparedness and Response”, 2024.
- Mariana Andrade; Joana Neves; Joana Marques; A Armada; Liliana Rodrigues; Miguel Viveiros; Henrique Silveira; et al. "Galleria mellonella research hub". 2024.
- <B><U>Andrade M</U></B>; Neves J; Marques J; Armada A; Rodrigues L; Viveiros M; Silveira H; Couto I; Costa SS. "<I>Galleria mellonella</I> research hub: a new <I>in vivo</I> infection model at GHTM/IHMT-NOVA". Trabalho apresentado em VII Conferência Internacional NOVAsaúde, 2024.
- <U>Ferreira C</U>; Leal M; <B>Andrade M</B>; Abrantes P; Viveiros M; Costa SS; Couto I. "Occurance of <I>norA</I> and other multidrug efflux pumps determinants across the <I>Staphylococcus</I> genus". Trabalho apresentado em VII Conferência Internacional NOVAsaúde, 2024.
- Mariana Pinto; Ana Lopes Tavares; Mayreli Ortiz; Vasoula Skouridou; Miriam Jauset-Rubio; Viveiros, Miguel; Ciara O’Sullivan; et al. "Detecção rápida de polimorfismos de nucleotídeo único em parasitas Plasmodium falciparum resistentes aos medicamentos antimaláricos através da amplificação isotérmica de ácidos nucleicos". Trabalho apresentado em 59º Congresso da Sociedade Brasileira de Medicina Tropical (MEDTROP 2024), 2024.
- Ferreira, Carolina; <b> Leal, Marta </b>; Andrade, Mariana; Abrantes, Patrícia; Viveiros, Miguel; Costa, Sofia Santos; Couto, Isabel. "Occurrence of norA and other multidrug efflux pump determinants across the Staphylococcus genus". Trabalho apresentado em 19th Internacional Symposium on Staphylococci and Staphylococcal Infections, 2024.
- Rodrigues, T; Andrade, Mariana; Marques, Joana; Rodrigues, Liliana; Viveiros, Miguel; Silveira, Henrique; Couto, Isabel; et al. "Implementation of a Galleria mellonella infection model at GHTM/IHMT-NOVA". Trabalho apresentado em Congress of Microbiology and Biotechnology 2023, 2023.
- Mariana Pinto; Ana Tavares; Mayreli Ortiz; Vasoula Skouridou; Miriam Jauset-Rubio; Miguel Viveiros; Ciara K. O'Sullivan; et al. Autor correspondente: Ana Lopes Tavares. "Rapid detection of single nucleotide polymorphisms associated with drug resistance in malaria parasites using isothermal amplification approach". Trabalho apresentado em Congresso de Saúde Pública 2023 ¿ Uma Nova Era, 2023.
- Ana Lopes Tavares; Miriam Jauset-Rubio; Mayreli Ortiz; Marcelo Urbano Ferreira; Diana Machado; Viveiros, Miguel; Ana Paula Arez; Ciara K. O' Sullivan. "Use of biosensors in the rapid detection of SNPs associated with resistance to antimalarials based on the isothermal amplification strategy". Trabalho apresentado em 6º Congresso Nacional de Medicina Tropical, 2023.
- Carolina Ferreira; Patricia Abrantes; Sofia Santos Costa; Miguel Viveiros; Isabel Couto; Carolina Ferreira; Abrantes, Patrícia; et al. "Occurence and variability of norA and other main multidrug efflux pump determinants across the Staphylococcus genus". Trabalho apresentado em European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), 2023.
- <u>Ferreira, Carolina</u>; <b>Costa, Sofia Santos</b>; Abrantes, Patrícia; Viveiros, Miguel; Couto, Isabel. "Rapid screening of <i>norA</i> alleles among <i>Staphylococcus aureus</i> strains causing SSTIs in different hosts". Trabalho apresentado em 32<sup>nd</sup> European Congress on Clinical Microbiology and Infectious Diseases (ECCMID), Lisbon/webconference, 2022.
- Carolina Ferreira; Sofia Santos Costa; Patricia Abrantes; Miguel Viveiros; Isabel Couto. "Rapid screening of norA alleles among Staphylococcus aureus strains causing SSTIs in different hosts". 2022.
- Bento-Cunha, Renata; Tatiana Vassilevskaia; Rodrigues, L; Viveiros, Miguel; Cunha, Celso. "Repsitioning drugs with potential activity against SARS-CoV-2 infection.". Trabalho apresentado em Microbiotec21, 2021.
- Silva, Carla; Antunes, Jessica; Serra, Débora; Toscano, Cristina; Viveiros, Miguel; Machado, Diana. "Detection of ß-lactamases and the simultaneous presence of increased efflux activity in Enterobacteriaceae using a 96-well microplate method.". Trabalho apresentado em MicroBiotec¿21, 2021.
- Silva, Carla; Viveiros, Miguel; Machado, Diana. "Optimization of a cost-effective method for the simultaneous detection of carbapenemases and efflux activity in Enterobacteriaceae". Trabalho apresentado em 31st European Congress of Clinical Microbiology & Infectious Diseases (ECCMID), 2021.
- Diana Machado; Gothe, Sarah; Martins, Marta C819-2F75-3A0A; Pacheco, Teresa; Batista, Judite; Toscano, Cristina; Viveiros, Miguel. "The emergence of high-level colistin resistance during treatment against heteroresistant Acinetobacter baumannii: a silent cause of treatment failure". Trabalho apresentado em 31st European Congress of Clinical Microbiology & Infectious Diseases (ECCMID), 2021.
- Renata Bento Cunha; Tatiana D. Vassilevskaia; Liliana Rodrigues; Miguel Viveiros; Celso Cunha. "Repositioning drugs with potential activity against SARS-CoV-2 infection.". 2021.
- Gothe, Sarah; Machado, Diana; Martins, Marta C819-2F75-3A0A; Pacheco, Teresa; Batista, Judite; Toscano, Cristina; Viveiros, Miguel. "Insights on colistin-heteroresistant Acinetobacter baumannii towards the development of effective therapies". Trabalho apresentado em III International Conference NOVAhealth Chronic Disease and Infection: Infection, Cancer and Global Health, 2020.
- Roseiro, Isabel; Machado, Diana; Viveiros, Miguel. "Tackling ß-lactam resistance in Escherichia coli ¿ the role of efflux pumps in ß-lactamase producing strains". Trabalho apresentado em NOVAhealth Chronic Disease and Infection "Infection, Cancer and Global Health", 2020.
- Diana Machado; Viveiros, Miguel; Pieroni, Marco. "Targeting Mycobacterium tuberculosis membrane energetics with lipophilic efflux inhibitors as adjuvants of tuberculosis treatment". Trabalho apresentado em III International Conference NOVAhealth Chronic Disease and Infection "Infection, Cancer and Global Health", 2020.
- Silva, Carla; Machado, Diana; Viveiros, Miguel. "Optimization of a cost-effective method for the simultaneous detection of ß-lactamases and efflux activity in Escherichia coli.". Trabalho apresentado em III International Conference NOVAhealth Chronic Disease and Infection "Infection, Cancer and Global Health", 2020.
- Diana Machado; Ravichandran, Rushiil; Machado, Diana; Kroger, Carsten; Viveiros, Miguel; Martins, Marta. "Tackling resistance to carbapenem and colistin in clinical isolates of Acinetobacter baumannii.". Trabalho apresentado em 30th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), 2020.
- Liliana Rodrigues; Pedro Cravo; Miguel Viveiros. "Targeting membrane transporters and energy metabolism in Mycobacterium tuberculosis through in silico drug repurposing". 2020.
- Rute Ribeiro; Sofia Santos Costa; Constança Pomba; Miguel Viveiros. "Biocide and antibiotic resistance in Staphylococcus aureus causing skin and soft tissue infections in companion animals". 2019.
- Sofia Santos Costa; Patricia Abrantes; C Morais; Miguel Viveiros; Adriana E. Rosato; Isabel Couto. "Exploring the staphylococcal efflux-mediated response to ethidium bromide, an efflux pump substrate". 2019.
- Sofia Santos Costa; SS Costa; S Santos Costa; Abrantes, Patrícia; Morais, Catarina; Viveiros, Miguel; Rosato, Adriana; Couto, Isabel. "Exploring the efflux-mediated multidrug resistance in staphylococci". Trabalho apresentado em National Congress of Microbiology and Biotechnology (MicroBiotec19). Coimbra, Portugal, 2019.
- Pereira, Bruna 5D1E-C298-769E; Machado, Diana; Silva, Carla; Viveiros, Miguel. "Exploring the contribution of efflux on the resistance to antibiotics, biocidesand dyes in clinical isolates of Escherichia coli". Trabalho apresentado em MicroBiotec¿19, 2019.
- Machado, Diana; Neves, Iolanda; Silva, Carla; Viveiros, Miguel. "Tackling bacterial infections by eliminating persister cells with efflux inhibitors.". Trabalho apresentado em MicroBiotec¿19, 2019.
- Machado, Diana; Pedrosa, Pedro; Piedade, João; Baptista, Pedro V.; Viveiros, Miguel. "Application of superparamagnetic nanoparticles for the early diagnosis of tuberculosis and HIV co-infection directly from respiratory samples.". Trabalho apresentado em Congresso Nacional de Microbiologia e Biotecnologia (MicroBiotec19), 2019.
- Maia, Inês; Machado, Diana; Viveiros, Miguel. "Evaluation of competition between substrates of the efflux pump system AcrAB-TolC of Escherichia coli using Red Nile.". Trabalho apresentado em Congresso Nacional de Microbiologia e Biotecnologia (MicroBiotec19), 2019.
- Roseiro, Isabel; Machado, Diana; Viveiros, Miguel. "The dark-side of drug resistance in Escherichia coli: efflux pumps and ß-lactamase producing strains.". Trabalho apresentado em Congresso Nacional de Microbiologia e Biotecnologia (MicroBiotec19), 2019.
- Ôchoa-Pires, Tiago; Froufe, Hugo; Barroso, Cristina; Machado, Diana; Rosa, Marguerita; Laranjeira, João; Seabra, Rafaela; et al. "Exploring Japanese quail immune repertoires for antibody discovery.". Trabalho apresentado em Congresso Nacional de Microbiologia e Biotecnologia (MicroBiotec19), 2019.
- Ribeiro, José; Machado, Diana; Viveiros, Miguel. "A bioinformatic approach to understand antibiotic resistance due to small multidrug resistant (SMR)-type efflux pumps in Acinetobacter baumannii through whole genome analysis.". Trabalho apresentado em Congresso Nacional de Microbiologia e Biotecnologia (MicroBiotec19), 2019.
- Tavares, Ana M.; Pingarilho, Marta; Batista, Judite; Toscano, Cristina; Dias, Sónia; Gomes, Perpétua; Viveiros, Miguel; Abecasis, Ana B.. "Sociodemographic and clinical characteristics of migrants and natives with HIV-TB co-infection in Portugal.". Trabalho apresentado em Ciência 2018, 2019.
- Machado, Diana; Pedrosa, Pedro; Piedade, João; Baptista, Pedro V.; Viveiros, Miguel. "Application of superparamagnetic nanoparticles for fast, simultaneous and non-invasive diagnosis of tuberculosis and HIV infection.". Trabalho apresentado em 40th Annual Congress of the European Society of Mycobacteriology, 2019.
- Sofia Santos Costa; Patricia Abrantes; C Morais; Miguel Viveiros; Isabel Couto. "Exploring the efflux-driven multidrug resistance in staphylococci". 2019.
- Machado, Diana; Azzali, Elisa; Couto, Isabel; Constantino, Gabriele; Pieroni, Marco; Viveiros, Miguel; Diana Machado; et al. "Adjuvant therapies against tuberculosis: discovery of a 2-aminothiazole targeting Mycobacterium tuberculosis energetics.". Trabalho apresentado em Multi-drug efflux systems: Gordon Research Conferences, 2019.
10.2217/fmb-2018-0110
- Machado, Diana; Costa, Raquel; Neves, Iolanda; Antunes, Jéssica; Couto, Isabel; Viveiros, Miguel. "Contribution of efflux to the emergence of antibiotic resistance in persister cells.". Trabalho apresentado em 28th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), 2019.
- Ramos, Jorge; Machado, Diana; Couto, Isabel; Viveiros, Miguel. "Diagnóstico laboratorial de micobactérias no Instituto de Higiene e Medicina Tropical: retrospetiva dos últimos 5 anos". Trabalho apresentado em 4º Congresso Nacional de Medicina Tropical, 2019.
- Theron, Maria; Machado, Diana; Couto, Isabel; Viveiros, Miguel. "Determination of efflux activity of Hoechst 33258 in Escherichia coli using a 96-well plate fluorescence assay.". Trabalho apresentado em NOVAsaude IV Genetics Workshop, 2019.
- Rodrigues, Fátima; Machado, Diana; Antunes, Jéssica; Couto, Isabel; Pacheco, teresa; Batista, Judite; Toscano, Cristina; Viveiros, Miguel. "Colistin resistance in Acinetobacter baumannii: correlation between mutations in target genes and active efflux.". Trabalho apresentado em NOVAsaude IV Genetics Workshop, 2019.
- Ribeiro, José; Machado, Diana; Antunes, Jéssica; Rodrigues, Fátima; Couto, Isabel; Pacheco, teresa; Batista, Judite; Toscano, Cristina; Viveiros, Miguel. "Prevalence of genes encoding small multidrug resistant (SMR)-type efflux pumps in Acinetobacter baumannii resistant to carbapenems isolated in hospital environment.". Trabalho apresentado em NOVAsaude IV Genetics Workshop, 2019.
- Neves, Iolanda; Machado, Diana; Costa, Raquel; Antunes, Jéssica; Mendes, Ângela; Castro, Rita; Couto, Isabel; Viveiros, Miguel. "Persister cells survive antibiotic treatment mounting an active response via activation of efflux pumps.". Trabalho apresentado em NOVAsaude IV Genetics Workshop., 2019.
- Machado, Diana; Perdigão, João; Ramos, Jorge; Tavares, Ana Maria; Abecasis, Ana; Dias, Sonia; Clark, Taane G.; et al. "Molecular epidemiology of antibiotic resistance genes in multi- and extensively drug-resistant Mycobacterium tuberculosis in Lisbon and its correlation with drug resistance levels". Trabalho apresentado em NOVAsaude IV Genetics Workshop, 2019.
- Liliana Rodrigues; Pedro Cravo; Miguel Viveiros. "Chemogenomics and in silico repurposing as an innovative approach for rapid drug discovery in tuberculosis.". 2019.
- Sofia Santos Costa; Mafalda Rosa; Frederico Holtreman; Ana Catarina Rodrigues; Miguel Viveiros; Constança Pomba; Isabel Couto. "Emergence of non-wild-type populations towards biocides in Staphylococcus epidermidis colonizing veterinary staff". 2018.
- Sofia Santos Costa; Adriana E. Rosato; Miguel Viveiros; Isabel Couto. "Development of multidrug resistance in staphylococci driven by efflux". 2018.
- Sofia Santos Costa; Mafalda Rosa; Adriana Belas; Miguel Viveiros; Constança Pomba; Isabel Couto. "Biocide susceptibility in Staphylococcus epidermidis causing infection in pets". 2018.
- Sofia Santos Costa; Cláudia Mineiro Santos; Miguel Viveiros; Constança Pomba. "Frequent biofilm production by Staphylococcus epidermidis causing infection in pets or colonizing veterinary staff". 2018.
- <b><u>Costa, Sofia Santos </b></u>; Kadlec, Kristina; Viveiros, Miguel; Melo-Cristino, José; Schwarz, Stefan; Couto, Isabel. "Complete sequences of two plasmids carrying genes for resistance to antibiotics, heavy-metals, biocides and/or virulence". Trabalho apresentado em 18<sup>th</sup> International Symposium of Staphylococci and Staphylococcal Infections (ISSSI), Copenhagen, Denmark, 2018.
- <b><u>Costa, Sofia Santos </b></u>; Santos, Cláudia Mineiro; Viveiros, Miguel; Pomba, Constança; Couto, Isabel. "Frequent biofilm production by <i>Staphylococcus epidermidis</i> causing infections in pets or colonizing veterinary staff". Trabalho apresentado em 18<sup>th</sup> International Symposium of Staphylococci and Staphylococcal Infections (ISSSI), Copenhagen, Denmark, 2018.
- <b><u>Costa, Sofia Santos </b></u>; Rosa, Mafalda; Holtreman, Frederico; Rodrigues, Ana Catarina; Viveiros, Miguel; Pomba, Constança; Couto, Isabel. "Emergence of non-wild-type populations towards biocides in <i>Staphylococcus epidermidis</i> colonizing veterinary staff". Trabalho apresentado em 18<sup>th</sup> International Symposium of Staphylococci and Staphylococcal Infections (ISSSI), Copenhagen, Denmark, 2018.
- <b><u>Costa, Sofia Santos </b></u>; Rosa, Mafalda; Belas, Adriana; Viveiros, Miguel; Pomba, Constança; Couto, Isabel. "Biocide susceptibility in <i>Staphylococcus epidermidis</i> causing infections in pets". Trabalho apresentado em 18<sup>th</sup> International Symposium of Staphylococci and Staphylococcal Infections (ISSSI), Copenhagen, Denmark, 2018.
- Tavares, Ana M.; Fronteira, Inês; Couto, Isabel; Machado, Diana; Viveiros, Miguel; Abecasis, Ana B.; Dias, Sónia. "HIV and tuberculosis co-infection among migrants in Europe: a systematic review". Trabalho apresentado em Ciência 2018, 2018.
- <b><u>Costa, Sofia Santos</u></b>; Lopes, Elizeth; Pieroni, Marco; Machado, Diana; Costantino, Gabriele; Viveiros, Miguel; Couto, Isabel. "<i>Mycobacterium smegmatis</i> model for the rapid screening of new compounds with efflux inhibitory activity and antimycobacterial activity". Trabalho apresentado em 1<sup>st</sup> Symposium of Tuberculosis and Non-tuberculous mycobacteria. Coimbra, Portugal, 2018.
- Perdigão, João; Silva, Carla; Diniz, Jaciara; Pereira, Catarina; Machado, Diana; Ramos, Jorge; Silva, Hugo; et al. "CPLP-TB: a novel framework and surveillance tool for tracing Mycobacterium tuberculosis strains across Lusophone countries.". Trabalho apresentado em 1º Simpósio de Investigação em Tuberculose e Micobactérias Não Tuberculosas em Portugal., 2018.
- Sofia Santos Costa; Mafalda Rosa; Ana Catarina Rodrigues; Cláudia Mineiro Santos; Frederico Holtreman; Miguel Viveiros; Constança Pomba; Isabel Couto. "Characterization of antimicrobial resistance in Staphylococcus epidermidis colonizing veterinary staff and students". 2017.
- Frederico Holtreman; Sofia Santos Costa; Mafalda Rosa; Miguel Viveiros; Constança Pomba; Isabel Couto. "Characterization of plasmid encoded efflux determinants from Staphylococcus epidermidis". 2017.
- Cláudia Mineiro Santos; Sofia Santos Costa; Miguel Viveiros; Constança Pomba; Isabel Couto. "Prevalence of biofilm production in Staphylococcus epidermidis colonizing veterinary staff and students". 2017.
- Brandão, Ângela; Machado, Diana; Pinhata, Juliana; Oliveira, Rosangela; Ferrazoli, Lucilaine; Chimara, Erica; Viveiros, Miguel. "Reliability of a multiplex allele-specific polymerase chain reaction (MAS-PCR) for the detection of multidrug-resistant Mycobacterium tuberculosis clinical isolates from Brazil.". Trabalho apresentado em Congresso Nacional de Microbiologia e Biotecnologia (MicroBiotec17), 2017.
- Antunes, Jéssica; Machado, Diana; Couto, Isabel; Pacheco, teresa; Batista, Judite; Toscano, Cristina; Viveiros, Miguel. "Correlation between carbapenem resistance, ß-lactamases, porins and efflux pumps in Acinetobacter baumannii clinical isolates.". Trabalho apresentado em Congresso Nacional de Microbiologia e Biotecnologia (MicroBiotec17), 2017.
- Laranjeira, João; Rosa, Marguerita; Machado, Diana; Francisco, Rafael; Viveiros, Miguel; Vieira-Pires, Ricardo. "Fighting bacterial infections with avian IgY antibodies.". Trabalho apresentado em Congresso Nacional de Microbiologia e Biotecnologia (MicroBiotec17), 2017.
- Silva, Mariana; Machado, Diana; Ramos, Jorge; Couto, Isabel; Viveiros, Miguel. "The contribution of efflux to ß-lactams resistance in non-ESBL-producing Escherichia coli clinical isolates". Trabalho apresentado em MicroBiotec17, 2017.
- Silva, Mariana; Machado, Diana; Ramos, Jorge; Couto, Isabel; Viveiros, Miguel. "The interplay between efflux and ß-lactamase activity in ß-lactams resistance in non-ESBLproducing Escherichia coli clinical isolates". Trabalho apresentado em NOVAsaude III Genetics Workshop, 2017.
- Moisés Francisco; Sofia Santos Costa; Adriana Belas; Jorge Ramos; Isabel Couto; Constança Pomba; Miguel Viveiros; et al. "Antimicrobial resistance and molecular characterization of Salmonella enterica serotype Typhi isolated in Luanda, Angola, in human specimens during 2013-2014". Trabalho apresentado em VIII Scientific Day of IHMT-NOVA. Lisbon, Portugal, 2017.
- <u>Francisco, Moisés</u>; <b>Costa, Sofia Santos</b>; Belas, Adriana; Ramos, Jorge; Couto, Isabel; Pomba, Constança; Viveiros, Miguel. "Antimicrobial resistance and molecular characterization of <i>Salmonella enterica</i> serotype Typhi isolated in Luanda, Angola, in human specimens during 2013-2014". Trabalho apresentado em Encontro Ciência 2017. Lisbon, Portugal, 2017.
- Isabel Couto; Sofia Santos Costa; Miguel Viveiros; Constança Pomba. "NorA mediated efflux in Staphylococcus epidermidis". 2017.
- Mafalda Rosa; Sofia Santos Costa; Miguel Viveiros; Constança Pomba; Isabel Couto. "Contribuição do efluxo para a resistência a compostos antimicrobianos em Staphylococcus epidermidis". 2017.
- Frederico Holtreman; Sofia Santos Costa; Mafalda Rosa; Miguel Viveiros; Constança Pomba; Isabel Couto. "Influência do efluxo na resistência a antibióticos e suscetibilidade reduzida aos biocidas em Staphylococcus epidermidis". 2017.
- Karen Mattos; Sofia Santos Costa; Isabel Couto; Carlos Emílio Levy; Cátia Marques; Patrícia Moriel; Constança Pomba; Miguel Viveiros. "Epidemiologia molecular e caracterização genética de estirpes de Klebsiella pneumoniae multirresistentes provenientes de um Hospital Universitário no Brasil". 2017.
- Cláudia Mineiro Santos; Sofia Santos Costa; Miguel Viveiros; Constança Pomba; Isabel Couto. "Correlação da produção de biofilme com a actividade de efluxo e resistência a antimicrobianos em Staphylococcus epidermidis". 2017.
- Machado, Diana; Coelho, Tatiane; Perdigão, João; Pereira, Catarina; Couto, Isabel; Portugal, Isabel; Maschmann, Raquel; et al. "Correlação entre a presença de mutações e a actividade de efluxo em isolados clínicos de Mycobacterium tuberculosis resistente aos antibióticos.". Trabalho apresentado em 3o Congresso Nacional de Medicina Tropical, 2017.
- Silva, Mariana; Machado, Diana; Couto, Isabel; Viveiros, Miguel. "A contribuição do efluxo na resistência aos ß-lactâmicos em Escherichia coli.". Trabalho apresentado em 3o Congresso Nacional de Medicina Tropical, 2017.
- Antunes, Jéssica; Machado, Diana; Couto, Isabel; Pacheco, teresa; Batista, Judite; Toscano, Cristina; Viveiros, Miguel. "Caracterização fenotípica e relação clonal entre isolados clínicos de Acinetobacter baumannii resistentes aos carbapenemos.". Trabalho apresentado em 3o Congresso Nacional de Medicina Tropical. Lisbon, Portugal, 2017.
- Costa, Raquel; Machado, Diana; Couto, Isabel; Viveiros, Miguel. "Estudo do efeito de fontes de carbono e inibidores de efluxo na susceptibilidade aos antibióticos em Escherichia coli.". Trabalho apresentado em 3º Congresso Nacional de Medicina Tropical, 2017.
- Sofia Santos Costa; Miguel Viveiros; Constança Pomba; Isabel Couto. "The role of efflux systems on antimicrobial resistance development in Staphylococcus epidermidis". 2017.
- Laranjeira, João; Machado, Diana; Francisco, Rafael; Rosa, Marguerita; Viveiros, Miguel; Vieira-Pires, Ricardo. "An avian antibody platform to fight bacterial infections.". Trabalho apresentado em 3rd Biologics and Biosimilars Congress, 2017.
- Diniz, Jaciara de Lourdes do Carmo Guimarães; Ramis I.; Abilleira, F.; Brum, C.; von Groll, A.; Silva A.; Ramos D.; et al. "Insights from the molecular epidemiological analysis of tuberculosis relapse cases in Rio Grande do Sul, Brazil". Trabalho apresentado em 27th ECCMID, 2017.
- Marrinhas, Carla; Santos, Marta; Marcos, Ricardo; Miranda, Sónia; Fernandes, Laura; Rodrigues, Catarina; Machado, Diana; Viveiros, Miguel; Pomba, Constança. "Infecção por Mycobacterium avium num gato em Portugal.". Trabalho apresentado em 7º Encontro de Formação da Ordem dos Médicos Veterinários, 2016.
- Tommaso Felicetti; Rolando Cannalire; Giuseppe Manfroni; Oriana Tabarrini; Diana Machado; Isabel Couto; Sofia Santos Costa; et al. "Natural isoflavone biochanin-A as a template for the design of new and potent 3-phenylquinolone inhibitors of the nontuberculous mycobacteria efflux pumps". 2016.
- Perdigão, João; Maltez, Fernando; Machado, Diana; Silva, Hugo; Pereira, Catarina; Silva, Carla; Couto, Isabel; Viveiros, Miguel; Portugal, Isabel. "Extensively drug resistant Tuberculosis plus linezolid resistance: the first report of linezolid resistance development in Lisbon, Portugal.". Trabalho apresentado em 8th iMed.ULisboa Postgraduate Students Meeting and 1st I3DU Meeting., 2016.
- Perdigão, João; Clemente, Sofia; Ramos, Jorge; Masakidi, Pedro; Machado, Diana; Silva, Carla; Couto, Isabel; et al. "First Insights on the Drug resistance and Genetic Diversity of Mycobacterium tuberculosis in Luanda, Angola". Trabalho apresentado em 26th ECCMID, 2016.
- Sofia Santos Costa; Adriana Belas; Natacha Couto; Catarina Rodrigues; Miguel Viveiros; Constança Pomba; Isabel Couto. "Biocide susceptibility profiles of staphylococci colonizing humans in close contact with pets". 2015.
- Machado, Diana; Couto, Isabel; Viveiros, Miguel. "Drug susceptibility testing for Mycobacterium avium complex strains using the MGIT960 system and the TB-eXIST software.". Trabalho apresentado em Congresso de Microbiologia e Biotecnologia (MicroBiotec15), 2015.
- Machado, Diana; Serra, Carlos; Viveiros, Miguel; Couto, Isabel. "Characterization of the mechanism of action of efflux inhibitors on the mycobacterial respiratory chain.". Trabalho apresentado em Congresso de Microbiologia e Biotecnologia (MicroBiotec15), 2015.
- Rabna, Paulo; Ramos, Jorge; Ponce, Gema; Sanca, Lilica; Mané, Morto; Armada, Ana; Machado, Diana; et al. "Laboratory fast direct detection and characterization of multi and poly drug-resistant tuberculosis in Guinea-Bissau". Trabalho apresentado em 3º Congresso Nacional de Medicina Tropical. Instituto de Higiene e Medicina Tropical, 2015.
- Coelho, Tatiane; Machado, Diana; Machmann, Raquel; von Groll, Andrea; Rossetti, Maria L; da Silva, Pedro E. Almeida; Viveiros, Miguel. "Efluxo como mecanismo envolvido na resistência antimicrobiana em isolados clínicos de Mycobacterium tuberculosis.". Trabalho apresentado em VII meeting of the Latino-American Society of Tuberculosis and other Mycobacteriosis, 2014.
- Sofia Santos Costa; Miguel Viveiros; Josè Melo-Cristino; Isabel Couto. "The role of efflux in the development of multidrug resistance phenotypes in Staphylococcus aureus". 2014.
- Sofia Santos Costa; Miguel Viveiros; Josè Melo-Cristino; Isabel Couto. "Impact of active efflux in the development of MDR phenotypes in Staphylococcus aureus". 2014.
- Machado, Diana; Silva, Vânia; Couto, Isabel; Ramos, Jorge; Viveiros, Miguel. "The interplay between mutations and efflux in acquired resistance to clarithromycin in Mycobacterium avium complex". Trabalho apresentado em 24th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), 2014.
- Rita Branquinho; Salomé Moço; Sofia Santos Costa; Isabel Couto; Miguel Viveiros; Rodrigo Martins; Elvira Fortunato. "Low cost paper-based materials functionalized with nanoparticles for antibacterial applications". 2014.
- Sofia Santos Costa; Miguel Viveiros; Josè Melo-Cristino; Isabel Couto. "Efflux as a first-line response to fluoroquinolones and other antimicrobials in Staphylococcus aureus". 2013.
- Sofia Santos Costa; Miguel Viveiros; Josè Melo-Cristino; Isabel Couto. "Characterization of a multiresistance plasmid from a methicillin-resistant Staphylococcus aureus clinical strain". 2013.
- Cláudia Palma; Sofia Santos Costa; Miguel Viveiros; Josè Melo-Cristino; Isabel Couto. "The role of plasmid determinants in the resistance of Staphylococcus aureus to antimicrobial agents". 2013.
- Serra, Carlos; Fernandes, Ana; Machado, Diana; Viveiros, Miguel; Salgueiro, Carlos; Couto, Isabel. "The role of type-II NADH-menaquinone oxidoreductase (NDH-2) on Mycobacterium tuberculosis resistance to drugs.". Trabalho apresentado em Congresso de Microbiologia e Biotecnologia (MicroBiotec13), 2013.
- Silva, Vânia; Machado, Diana; Ramos, Jorge; Couto, Isabel; Viveiros, Miguel. "Contribution of efflux systems to clarithromycin resistance in Mycobacterium avium complex.". Trabalho apresentado em MicroBiotec13, 2013.
- Machado, Diana; Pires, David; Perdigão, João; Ramos, Jorge; Couto, Isabel; Portugal, Isabel; ANES, ELSA; Viveiros, Miguel. "Efflux inhibitors against drug resistant Mycobacterium tuberculosis: antimicrobial agents and enhancers of macrophage killing activity". Trabalho apresentado em MicroBiotec13, 2013.
- Machado, Diana; Couto, Isabel; Ramos, Jorge; Viveiros, Miguel. "Contribution of efflux pumps to overall antibiotic resistance in Mycobacterium tuberculosis and the usefulness of efflux inhibitors as ¿helper compounds¿ in drug therapy". Trabalho apresentado em 23rd European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), 2013.
- Pedrosa, Pedro; Viegas, Bruno; Machado, Diana; Perdigão, João; Portugal, Isabel; Couto, Isabel; Viveiros, Miguel; Baptista, Pedro V.. "Gold nanoprobes methodology for diagnosis of multi-drug resistant tuberculosis.". Trabalho apresentado em NanoPT, 2013.
- Sofia Santos Costa; Miguel Viveiros; Isabel Couto. "Relevância clínica de sistemas de efluxo na resistência a compostos antimicrobianos em Staphylococcus aureus". 2012.
- Gröblacher, Barbara; Armada, Ana; Machado, Diana; Viveiros, Miguel; Bucar, Franz. "Mycobacterial efflux inhibitors from Aframomum melegueta.". Trabalho apresentado em II International Conference on Antimicrobial Research (ICAR), 2012.
- Machado, Diana; Couto, Isabel; Ramos, Jorge; Viveiros, Miguel. "Efflux inhibitors as adjuvants in drug resistant tuberculosis therapy". Trabalho apresentado em EMBO Conference: Tuberculosis 2012: Biology, pathogenesis, intervention strategies, 2012.
- Cláudia Mourato; Sofia Santos Costa; Miguel Viveiros; Leonard Amaral; Josè Melo-Cristino; Isabel Couto. "Co-resistance to biocides and beta-lactams in a MRSA clinical isolate". 2012.
- Sofia Santos Costa; Miguel Viveiros; Leonard Amaral; Patrick Butaye; Isabel Couto. "Susceptibility profiles of antibiotics, biocides and dyes in Staphylococcus aureus from pigs: correlation with efflux activity". 2012.
- Sofia Santos Costa; Miguel Viveiros; Leonard Amaral; Josè Melo-Cristino; Isabel Couto. "Efflux-mediated resistance to quaternary ammonium compounds in methicillin resistant Staphylococcus aureus (MRSA) clinical isolates". 2012.
- Mourato, Cláudia; Costa, Sofia Santos; Viveiros, Miguel; Amaral, Leonard; Melo-Cristino, José; Couto, Isabel. "Co-resistance to biocides and beta-lactams in a methicillin-resistant Staphylococcus aureus (MRSA) clinical isolate". Trabalho apresentado em 15th International Symposium on Staphylococci and Staphylococcal Infections (ISSSI), 2012.
- Sofia Santos Costa; Cláudia Mourato; Miguel Viveiros; Josè Melo-Cristino; Leonard Amaral; Isabel Couto. "Resistance to biocides conveyed by efflux pumps in clinical isolates of MRSA". 2012.
- Sofia Santos Costa; Miguel Viveiros; Leonard Amaral; Isabel Couto. "The role of NorA in the adaptative response of Staphylococcus aureus to stress stimuli". 2012.
- Costa, Sofia Santos; Mourato, Cláudia; Viveiros, Miguel; Melo-Cristino, José; Amaral, Leonard; Couto, Isabel. "Resistance to biocides in clinical MRSA isolates conveyed by efflux pumps". Trabalho apresentado em 22nd European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), 2012.
- Machado, Diana; Rodrigues, Liliana; Couto, Isabel; Amaral, Leonard; Viveiros, Miguel. "The emergence of clarithromycin resistance in Mycobacterium avium complex.". Trabalho apresentado em 22nd European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), 2012.
- Sofia Santos Costa; Cláudia Mourato; Miguel Viveiros; Josè Melo-Cristino; Isabel Couto; Leonard Amaral. "Description of a novel staphylococcal pC194-family plasmid carrying the smr efflux pump gene". 2011.
- PINTO Antónia Rosa Trindade; Diana Machado; Sofia Santos Costa; Isabel Couto; Leonard Amaral; Miguel Viveiros. "Multidrug resistance mediated by active efflux in Escherichia coli". 2011.
- Cláudia Mourato; Sofia Santos Costa; Miguel Viveiros; Celeste Falcão; Josè Melo-Cristino; Leonard Amaral; Isabel Couto. "Multidrug resistance in a methicillin-resistant Staphylococcus aureus (MRSA) clinical isolate mediated by efflux pump QacA". 2011.
- <u>Mourato, Cláudia</u>; <b>Costa, Sofia Santos</b>; Viveiros, Miguel; Falcão, Celeste; Melo-Cristino, José; Amaral, Leonard; Couto, Isabel. "Multidrug resistance in a methicillin-resistant <i>Staphylococcus aureus</i> (MRSA) clinical isolate mediated by efflux pump QacA". Trabalho apresentado em National Congress of Microbiology and Biotechnology (MicroBiotec11). Braga, Portugal, 2011.
- <b><u>Costa, Sofia Santos</b></u>; Viveiros, Miguel; Amaral, Leonard; Couto, Isabel. "The role of NorA in the adaptative response of <i>Staphylococcus aureus</i> to stress stimuli". Trabalho apresentado em National Congress of Microbiology and Biotechnology (MicroBiotec11). Braga, Portugal, 2011.
- <b><u>Costa, Sofia Santos</b></u>; Mourato, Cláudia; Viveiros, Miguel; Melo-Cristino, José; Couto, Isabel. "Description of a novel staphylococcal pC194-family plasmid carrying the <i>smr</i> efflux pump gene". Trabalho apresentado em National Congress of Microbiology and Biotechnology (MicroBiotec11). Braga, Portugal, 2011.
- Pinto, Antónia; Machado, Diana; Costa, Sofia S; Couto, Isabel; Amaral, Leonard; Viveiros, Miguel; <u>Pinto, Antónia</u>; Machado, Diana; <b>Costa, Sofia Santos </b>. "Multidrug resistance mediated by active efflux in Escherichia coli: new therapeutic strategies using antibiotics and inhibitors of active efflux.". Trabalho apresentado em Congresso de Microbiologia e Biotecnologia (MicroBiotec11), 2011.
- Francisco, Samuel; Machado, Diana; Viveiros, Miguel; Ramos, Jorge; Pacheco, Teresa; Melo Cristino, José; Lito, Luís Marques; et al. "Application of molecular methods for the direct detection of MDR-TB". Trabalho apresentado em MicroBiotec11, 2011.
- <b><u>Costa, Sofia Santos</b></u>; Mourato, Cláudia; Viveiros, Miguel; Melo-Cristino, José; Amaral, Leonard; Couto, Isabel. "Description of a novel pC194-family plasmid carrying the <i>smr</i> efflux pump gene". Trabalho apresentado em 51<i>st</i> Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC). Chicago, USA, 2011.
- Cerca, Pedro; Machado, Diana; Viveiros, Miguel; Amaral, Leonard; Couto, Isabel. "Identification of nontuberculous mycobacteria: comparison of three in-house molecular protocols.". Trabalho apresentado em 51st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), 2011.
- Sofia Santos Costa; Cláudia Mourato; Miguel Viveiros; Josè Melo-Cristino; Isabel Couto; Leonard Amaral. "Description of a novel pC194-family plasmid carrying the smr efflux pump gene". 2011.
- Machado, Diana; Couto, Isabel; Rodrigues, Liliana; Amaral, Leonard; Viveiros, Miguel. "Efflux activity in Mycobacterium tuberculosis as an intrinsic mechanism of resistance to isoniazid.". Trabalho apresentado em 32nd Annual Congress of the European Society of Mycobacteriology, 2011.
- Machado, Diana; Couto, Isabel; Amaral, Leonard; Portugal, Isabel; Baptista, Pedro V.; Viveiros, Miguel. "Selection for mutator phenotypes in Mycobacterium tuberculosis.". Trabalho apresentado em 32nd Annual Congress of the European Society of Mycobacteriology, 2011.
- Machado, Diana; Couto, Isabel; Rodrigues, Liliana; Perdigão, João; Portugal, Isabel; Amaral, Leonard; Viveiros, Miguel. "Phenotypic adaptation to isoniazid in Mycobacterium tuberculosis: a pathway to multidrug resistant tuberculosis.". Trabalho apresentado em 21st European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), 2011.
- Rodrigues, Liliana; Machado, Diana; Couto, Isabel; Amaral, Leonard; Viveiros, Miguel. "Contribution of efflux activity to isoniazid resistance in Mycobacterium tuberculosis complex.". Trabalho apresentado em 21st European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), 2011.
- Raúl Saraiva; Sofia Santos Costa; Isabel Couto; Miguel Viveiros; Maria José Feio; Paula Gameiro. "The role of enrofloxacin-based-metallocomplexes in the war against bacterial resistance". 2010.
- Viegas, Bruno; Machado, Diana; Perdigão, João; Portugal, Isabel; Couto, Isabel; Viveiros, Miguel; Baptista, Pedro V.. "A PCR-Au-nanoprobes combined approach for detection of mutations associated with antibiotic resistance in Mycobacterium tuberculosis.". Trabalho apresentado em 11th Trends in Nanotechnology International Conference (TNT2010), 2010.
- Sofia Santos Costa; Miguel Viveiros; Celeste Falcão; Josè Melo-Cristino; Leonard Amaral; Isabel Couto; <u><b>Costa, Sofia Santos</u></b>; et al. "Genetic diversity of the Staphylococcus aureus efflux pump gene norA". Trabalho apresentado em National Congress of Microbiology (Micro09). Vilamoura, Portugal, 2010.
- Ramos, Jorge; Machado, Diana; Couto, Isabel; Amaral, Leonard; Viveiros, Miguel. "Evaluation of the BD MGIT¿ TBc identification test for the rapid detection of Mycobacterium tuberculosis complex from cultures". Trabalho apresentado em 31th Annual Congress of the European Society of Mycobacteriology, 2010.
- <u><b>Costa, Sofia Santos</u></b>; Falcão, Celeste; Viveiros, Miguel; Melo-Cristino, José; Amaral, Leonard; Couto, Isabel; Sofia S. Costa; et al. "Importance of efflux systems on the resistance to fluoroquinolones in <i>Staphylococcus aureus</i>". Trabalho apresentado em 20<sup>th</sup> European Congress of Clinical Microbiology and Infectious Diseases (ECCMID). Vienna, Austria, 2010.
- MARTINS Marta Sofia Lopes; Miguel Viveiros; Isabel Couto; Sofia Santos Costa; Teresa Pacheco; Leonard Amaral. "New method for the rapid screening of efflux pump activity in multi-drug resistant clinical strains". 2009.
- Cerca, Pedro; Machado, Diana; Viveiros, Miguel; Amaral, Leonard; Couto, Isabel. "Identification of non-tuberculous mycobacteria by molecular methods: comparison of three in-house protocols.". Trabalho apresentado em Congresso de Microbiologia e Biotecnologia (MicroBiotec09), 2009.
- Rodrigues, Liliana; Sampaio, Daniela; Couto, Isabel; Machado, Diana; Kern, Winfried V.; Amaral, Leonard; Viveiros, Miguel. "The role played by efflux pump in macrolide resistance in Mycobacterium avium complex.". Trabalho apresentado em Congresso de Microbiologia e Biotecnologia (MicroBiotec09), 2009.
- Ramos, Jorge; Rodrigues, Liliana; Couto, Isabel; Amaral, Leonard; Viveiros, Miguel. "The effect of efflux pumps inhibitors on the transport of ethidium bromide and antimicrobials across Mycobacterium smegmatis cell wall". Trabalho apresentado em Microbiotec09, 2009.
- Couto, Isabel; Machado, Diana; Viveiros, Miguel; Rodrigues, Liliana; Amaral, Leonard. "Identification of nontuberculous mycobacteria in clinical samples using molecular methods: a three-year study.". Trabalho apresentado em 30th Annual Congress of the European Society of Mycobacteriology, 2009.
- Ramos, Jorge; Rodrigues, Liliana; Couto, Isabel; Amaral, Leonard; Viveiros, Miguel. "Methods for assessment of ethidium bromide transport across Mycobacterium smegmatis cell wall". Trabalho apresentado em 30th Annual congress of European Society of Mycobacteriology, 2009.
- Couto, Isabel; Viveiros, Miguel; Machado, Diana; Rodrigues, Liliana; Amaral, Leonard. "Identificação de micobactérias atípicas em amostras clínicas utilizando métodos moleculares.". Trabalho apresentado em IX Congresso Nacional de Doenças Infecciosas e Microbiologia Clínica, Sida e Parasitologia, 2008.
- Rodrigues, Liliana; Viveiros, Miguel; Sampaio, Daniela; Couto, Isabel; Machado, Diana; Vavra, Martina; Wagner, Dirk; Kern, Winfried V.; Amaral, Leonard. "O Papel das bombas de efluxo na resistência aos antibióticos em micobactérias do complexo M. avium.". Trabalho apresentado em IX Congresso Nacional de Doenças Infecciosas e Microbiologia Clínica, Sida e Parasitologia, 2008.
- Sofia Santos Costa; Isabel Couto; Miguel Viveiros; MARTINS Marta; Clara Leandro; Leonard Amaral; <u><b>Costa, Sofia Santos</u></b>; et al. "Characterization of reduced susceptibility to biocides, dyes, and quinolones in a Staphylococcus aureus strain exposed to ethidium bromide". Trabalho apresentado em National Congress of Microbiology (Micro07). Lisbon, Portugal, 2007.
- Couto, Isabel; Machado, Diana; Viveiros, Miguel; Rodrigues, Liliana; Amaral, Leonard. "Molecular identification of non-tuberculosis mycobacteria from Lisbon hospitals: a two-year study.". Trabalho apresentado em MICRO¿07 BIOTEC¿07-XXXIII JPG, 2007.
- Couto, Isabel; Viveiros, Miguel; Machado, Diana; Rodrigues, Liliana; Martins, Marta; Amaral, Leonard. "Identification of non-tuberculosis mycobacteria in clinical samples using molecular methods: a two-year study.". Trabalho apresentado em 47th International Congress on Antimicrobial Agents and Chemotherapy, 2007.
- T Faria; R Carvalho; C Araújo; Nina, Jaime; T Pacheco; Viveiros, Miguel; F Borges; et al. "Admited cases of tuberculosis (TB) and resistant TB in a central hospital (Egas Moniz Hospital): evaluation of a three years period - January 1996 to December 1998". Trabalho apresentado em 7th European Conference on Clinical Aspects and Treatment of HIV-Infection, 1999.
- W.F. Canas Ferreira; A. Santos Pinto; A.P. Silva; E. Prieto; R. Albuquerque; C. Costa; F. Dias; et al. "Natural history of HIV-2 infection in an urban population from Guinea-Bissau: clinical and immunologic outcome, 1986-1992". 1993.
- João Piedade; Miguel Viveiros; C. Costa; A. Santos Pinto; E. Prieto; R. Albuquerque; L. Brum; et al. "Seroprevalence and risk factors associated with HIV infection in Guinea-Bissau". 1992.
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| Pré-impressão |
- Maceiras AR; Silva ML; Couto J; Gonçalves R; Silva M; Macedo S; Machado D; et al. "Activation of nuclear receptors correlates with tuberculosis severity and is a target for host-directed therapy". 2025. http://europepmc.org/abstract/PPR/PPR1055066.
10.1101/2025.07.23.666296
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| Resumo em conferência |
- <u>Andrade M</u>; Neves J; Rita P; Nunes M; Seabra SG; Armada A; Viveiros M; et al. Autor correspondente: <B> Costa SS</B>. "Targeting efflux and biofilms: new candidate drugs for repurposing against antimicrobial-resistant Gram-positive bacteria". Trabalho apresentado em e-Conference on Innovation in Microbial Control, Online, 2025.
- <u>Andrade M</u>; Neves J; Bento M; Marques J; Viveiros M; Rodrigues L; Armada A; et al. Autor correspondente: <b>Costa SS</b>. "<i>Galleria mellonella</i>: um modelo <i>in vivo</i> fidedigno para avaliar a eficácia de fármacos para a terapêutica de infeções provocadas por estafilococos". Trabalho apresentado em Oral presentation at Microbiologia 2024, Online, 2024.
- M. Andrade; Joana Neves; Maria Bento; Joana Marques; Miguel Viveiros; Liliana Rodrigues; A Armada; et al. "Galleria mellonella as a reliable in vivo model to evaluate repurposed drugs for Staphylococcus infection therapeutics". Trabalho apresentado em 19<sup>th</sup> International Symposium of Staphylococci and Staphylococcal Infections (ISSSI), Perth, Australia, Perth, 2024.
- <u>Andrade M</u>; Neves J; Bento M; Marques J; Viveiros M; Rodrigues L; Armada A; et al. Autor correspondente: <b>Costa SS</b>. "<i>Galleria mellonella</i> as a reliable <i>in vivo</i> model to evaluate repurposed drugs for <i>Staphylococcus</i> infection therapeutics". Trabalho apresentado em Oral presentation at 19<sup>th</sup> International Symposium of Staphylococci and Staphylococcal Infections (ISSSI), Perth, 2024.
- Neves, Joana; Andrade, Mariana; Bento, Maria; Viveiros, Miguel; Rodrigues, Liliana; Couto, Isabel; Costa, S. Sofia. "New candidate drugs for repurposing as efflux inhibitors and antibiofilm agents against antimicrobial-resistant staphylococcus aureus and staphylococcus epidermidis.". Trabalho apresentado em Accepted for oral presentation at 19th International Symposium on Staphylococci and Staphylococcal Infections (ISSSI), 18-21 August, Perth., Perth, 2024.
- Ana Tavares; Miriam Jauset-Rubio; Mayreli Ortiz; Marcelo U. Ferreira; Diana Machado; Miguel Viveiros; Arez, Ana Paula; Ciara K. O'Sullivan. "Utilização de biosensores na deteção rápida de SNPs associados à resistência aos antimaláricos com base na estratégia de amplificação isotérmica.". 2023.
- Diana Machado; Sarah Gothe; Marta Martins; Teresa Pacheco; Judite Batista; Cristina Toscano; Miguel Viveiros. "Colistin heteroresistance in carbapenemase-producing Acinetobacter baumannii". 2020.
- Diana Machado; Marco Pieroni; Miguel Viveiros. "Development of lipophilic efflux inhibitors as adjuvants of Mycobacterium tuberculosis chemotherapy". 2020.
- Thomas Schön; Erja Chryssanthou; H.Benmansour Florian Maurer; S. Boarbi; Petter Keller; Miguel Viveiros; Diana Machado; et al. "ECOFFs for non-tuberculous mycobacteria: towards a EUCAST reference method and clinical breakpoints for antimicrobial susceptibility testing". 2020.
- Diana Machado; Elisa Azzali; Isabel Couto; Gabriele Costantino; Marco Pieroni; Miguel Viveiros. "Targeting Mycobacterium tuberculosis with lipophilic efflux inhibitors exploring their dual activity: dissipation of the proton motive force and efflux inhibition". 2019.
- Jéssica Antunes; Diana Machado; Marta Martins; Isabel Couto; Teresa Pacheco; Judite Batista; Cristina Toscano; Miguel Viveiros. "Contribution of ß-lactamases, porins and efflux pumps to carbapenem resistance in Acinetobacter baumannii". 2019.
- Diana Machado; João Perdigão; Jorge Ramos; Ana Tavares; Abecasis AB; Sónia Dias; Taane G. Clark; et al. "Exploring the phenotypic and genetic basis of drug-resistant Mycobacterium tuberculosis strains in Lisbon, Portugal". 2019.
- Sarah Gothe; Diana Machado; Marta Martins; Teresa Pacheco; Judite Batista; Cristina Toscano; Miguel Viveiros. "Insights on Acinetobacter baumannii heteroresistance to colistin: what is the fate?". 2019.
- Miguel Viveiros; Diana Machado; Iolanda Neves; Marta Martins; Isabel Couto; Teresa Pacheco; Judite Batista; Cristina Toscano. "The contribution of membrane transporter proteins to extensively-drug resistant phenotypes in Acinetobacter baumannii". 2019.
- Thomas Schön; Miguel Viveiros; Jim Werngren; Daniella Cirrillo; Emanuele Borroni; Maria Wijkander; Diana Machado; et al. "Towards a new reference drug susceptibility testing method for Mycobacterium tuberculosis". 2019.
- Liliana Rodrigues; Pedro Cravo; Miguel Viveiros. "In silico repurposing of approved drugs against tuberculosis: targeting membrane transporters and energy metabolism". 2019.
- Diana Machado; João Perdigão; Jorge Ramos; Ana Tavares; Abecasis AB; Sónia Dias; Taane Clark; et al. "Epidemiologia molecular da resistência em Mycobacterium tuberculosis multirresistente em Lisboa". 2019.
- Denise O'Sullivan; Jody Phelan; Diana Machado; Miguel Viveiros; Taane G. Clark; Justin O'Grady; Jim F. Huggett. "Evaluation of the performance of MinION sequencing to identify multi- and extensively drug resistant tuberculosis". 2018.
- João Perdigão; Carla Silva; Jaciara Diniz; Catarina Pereira; Diana Machado; Jorge Ramos; Fernanda Silva; et al. "Genetic diversity and mapping of M. tuberculosis strains in Portuguese Speaking Countries". 2017.
- Jéssica Antunes; Diana Machado; Isabel Couto; Teresa Pacheco; Judite Batista; Cristina Toscano; Miguel Viveiros. "The contribution of efflux pumps and porins in Acinetobacter baumannii resistance to carbapenems". 2017.
- João Perdigão; Carla Silva; Jaciara Diniz; Catarina Pereira; Diana Machado; Jorge Ramos; Fernanda Silva; et al. "Tracking Mycobacterium tuberculosis across the seas: CPLP-TB and genetic diversity in the Lusophone space". 2017.
- A Armada; Bruno Costa Gomes; Jose Rueff; Miguel Viveiros; Antonio Sebastião Rodrigues. "Evaluation of the modulating effect of miR-203 and miR-200c on drug extrusion by ABCB1". 2017.
- Santos-Gomes, G; M. Rafael-Fernandes; A Armada; P. Ruas; J.H. Lago; F. Passero; Miguel Viveiros. "Eficácia da terapia combinada como estratégia alternativa ao tratamento convencional das leishmanioses.". 2017.
- Diana Machado; Faiza Mougari; Emmanuelle Cambau; Miguel Viveiros. "Genome downsizing and drug resistance in Mycobacterium leprae: are there places for drug efflux pumps?". 2016.
- A Armada; Bruno Costa Gomes; Jose Rueff; Antonio Sebastião Rodrigues; Miguel Viveiros. "MicroRNAs 203 e 200c regulam a expressão das bombas ABCB1 na resistência à doxorubicina". 2016.
- T. Mendes; A. Pinto-Almeida; Pedro Ferreira; A Armada; Miguel Viveiros; Silvana Belo; A. Afonso. "Avaliação do envolvimento das bombas de efluxo na fármaco-resistência ao Praziquantel em Schistosoma mansoni.". 2014.
- Cabral, V; Luo, X; Junqueira, E; Costa, S; Mulhovo, S; Duarte, A; Couto, I; Viveiros, M; Ferreira, MJU. "Zanthoxylum capense constituents and derivatives: Effects on the activity of antibiotics against Staphylococcus aureus strains". 2014.
10.1055/s-0034-1395089
- Martins, C; Armada, A; Viveiros, M; Rueff, J; Rodrigues, AS. "Allylbenzenes as potential chemosensitizers and P-glycoprotein inhibitors". 2013.
- Diana Machado; Isabel Couto; Jorge Ramos; Miguel Viveiros. "Inibidores de efluxo como adjuvantes no tratamento da tuberculose resistente aos antibacilares". 2013.
- Diana Machado; Miguel Viveiros; Samuel Francisco; Jorge Ramos; Carlos Serra; Teresa Pacheco; Teresa Marques; et al. "Detecção directa de MDRTB em Portugal: métodos e aplicações comerciais. A experiência do IHMT". 2013.
- Pedro Pedrosa; Bruno Veigas; Diana Machado; João Perdigão; Isabel Portugal; Isabel Couto; Miguel Viveiros; P. V. Baptista. "Detecção de MDRTB por gold-nanoprobes – uma nova abordagem tecnológica desenvolvida em Portugal". 2013.
- Miguel Viveiros; Liliana Rodrigues; Diana Machado; Marta Martins; Isabel Couto; Leonard Amaral. "Significance of efflux in multidrug resistance in Mycobacterium tuberculosis". 2013.
- Paulo Rabna; Jorge Ramos; Gema Ponce; Fina Bamba; Diana Machado; A Armada; Lilica Sanca; et al. "Detecção directa da TB-MR através do teste Xpert MTB/RIF na Guiné-Bissau". 2013.
- Diana Machado; Isabel Couto; Jorge Ramos; Miguel Viveiros. "Anti-tuberculosis activity of efflux inhibitors against drug resistant Mycobacterium tuberculosis". 2013.
- Diana Machado; João Perdigão; Jorge Ramos; Isabel Couto; Isabel Portugal; Claudia Ritter; Erik C. Boettger; Miguel Viveiros. "High level resistance to isoniazid and ethionamide among multidrug resistant Mycobacterium tuberculosis strains from Lisbon, Portugal, is associated with double mutations in inhA gene". 2012.
- Diana Machado; João Perdigão; Jorge Ramos; Isabel Couto; Isabel Portugal; Claudia Ritter; Eric C. Boettger; Miguel Viveiros. "Resistência de alto nível à isoniazida e etionamida em estirpes de Mycobacterium tuberculosis multirresistentes está associada a mutações duplas no gene inhA". 2012.
- Miguel Viveiros; Diana Machado; Isabel Couto; João Perdigão; Isabel Portugal; Emmanuelle Cambau; Erik C. Boettger. "O teste de susceptibilidade semi-quantitativo de 1a e 2a linha para Mycobacterium tuberculosis usando o sistema BD EpiCenterTM TB-eXiST: um importante contributo para a Luta Contra a Tuberculose Resistente aos antibióticos". 2012.
- Martins, A; Vasas, A; Schelz, Z; Martins, M; Viveiros, M; Molnar, J; Hohmann, J; Amoral, L. "Purification and identification of active compounds of Carpobrotus edulis against the reversal of resistance of human mdr1 gene transfected mouse lymphoma cells". 2008.
- Amaral, L; Spengler, G; Viveiros, M; Rodrigues, L; Martins, A; Couto, I; Martins, M; et al. "ASSESSMENT AND COMPARISON OF EFFLUX PUMPS OF CANCER CELLS AND MDR BACTERIA UNDER PHYSIOLOGICAL CONDITIONS BY A REAL-TIME SEMI-AUTOMATED SYSTEM". 2008.
- Spengler, G; Viveiros, M; Martins, A; Rodrigues, L; Martins, M; Molnar, J; Couto, I; Amaral, L. "DEMONSTRATION OF THE ACTIVITY OF P-GLYCOPROTEIN BY A FULLY AUTOMATED ETHIDIUM BROMIDE METHOD". 2008.
- Amaral, L; Ordway, D; Viveiros, M; Martins, M; Leandro, C. "Thioridazine: evidence supporting its use as alternative therapy for MDR-TB". 2004.
- Amaral, L; Martins, M; Viveiros, M; Leandro, C; Ordway, D; Molnar, J. "VERAPAMIL AND RESERPIN PROMOTE THE KILLING OF INTRACELLULAR BACTERIA". 2004.
- João Piedade; Miguel Viveiros; C. Costa; A. Santos Pinto; E. Prieto; R. Albuquerque; A. Paulo Silva; et al. "HIV-2 seroprevalence in Guinea-Bissau". 1993.
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| Revisão de livro |
- Guerreiro, Cátia Sá; Hartz, Zulmira; Sambo, Luís; Conceição, Cláudia; Dussault, Gilles; Russo, Giuliano; Viveiros, Miguel; et al. "Scientific Research Policy for Health in Portugal: II - Facts and Suggestions". https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/8012.
- Sá Guerreiro, Cátia; Hartz, Zulmira; Sambo, Luís; Conceição, Cláudia; Dussault, Gilles; Russo, Giuliano; Viveiros, Miguel; et al. "Scientific Research Policy for Health in Portugal: I - European and National Environment". https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/8011.
- Simões, Alexandra S.; Couto, Isabel; Toscano, Cristina; Gonçalves, Elsa; Póvoa, Pedro; Viveiros, Miguel; Lapão, Luís V.; et al. "Prevention and control of antimicrobial resistant healthcare-associated infections". 7, JUN (2016): http://hdl.handle.net/10362/116814.
https://doi.org/10.3389/fmicb.2016.00855
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| Tese / Dissertação |
- Matos, Sofia Ferra de. "Global Genomic Diversity, Population Structure and Drug Resistance in the Mycobacterium avium complex". Mestrado, 2025. http://hdl.handle.net/10362/191881.
- NASCIMENTO, Teresa Maria Silva do. "Caracterização do micobioma em unidades de cuidados intensivos". Doutoramento, 2025. http://hdl.handle.net/10362/187828.
- Veríssimo Almeida, Maria João. "Molecular characterization of clinical isolates of the Mycobacterium abscessus complex circulating in Lisbon". Mestrado, 2024. http://hdl.handle.net/10362/182261.
- De Jesus Vila Boa Menino, Filipa. "Towards the establishment of a reference method for Mycobacterium avium drug susceptibility testing". Mestrado, 2024. http://hdl.handle.net/10362/181981.
- MAIA, Inês Lopes Pinheiro de Oliveira. "Estudo de competição entre substratos de bombas de efluxo em isolados clínicos de Escherichia coli por fluorimetria em tempo real usando Vermelho do Nilo". Mestrado, 2022. http://hdl.handle.net/10362/146124.
- VIEGAS, Sarah Gothe Esteves. "Insights on the mechanisms underlying the development of heteroresistance to colistin in Acinetobacter baumannii". Mestrado, 2022. http://hdl.handle.net/10362/159181.
- Ribeiro, José Francisco Valente. "Uma abordagem bioinformática para o estudo da contribuição das bombas de efluxo “Small Multidrug Resistance” na resistência aos antibióticos em Acinetobacter baumannii através da análise de genoma completo". Mestrado, 2020. http://hdl.handle.net/10362/93123.
- Serra, Débora Carvalho. "Detection and inhibition of ß-lactamase activity in clinical isolates of Escherichia coli combining ß-lactamase and efflux inhibitors using an MTT-based method: phenotypic and genotypic validation". Mestrado, 2020. http://hdl.handle.net/10362/97300.
- ARMADA, Ana Maria Buttle de Mendonça Mourão Possidónio de. "ABC efflux pumps in eukaryotic cells from function to regulation". Doutoramento, 2019. http://hdl.handle.net/10362/66659.
- FERREIRA, Mónica Eduarda Franco. "Diagnóstico e tratamento da infeção malárica: desenvolvimento de uma nova plataforma de diagnóstico e de um novo composto antimalárico". Mestrado, 2019. http://hdl.handle.net/10362/66269.
- RODRIGUES, Fátima Alexandra Tavares. "Caracterização dos mecanismos de resistência à colistina em isolados clínicos de Acinetobacter baumannii resistentes aos carbapenemos". Mestrado, 2019. http://hdl.handle.net/10362/116358.
- TAVARES, Ana Maria Pinho. "HIV, tuberculosis and co-infection among migrant populations living in Portugal". Doutoramento, 2019. https://www.authenticus.pt/P-010-V7N.
- COSTA, Ana Raquel Esteves. "Contribuição do efluxo para a emergência da resistência em bactérias persistentes". Mestrado, 2018. http://hdl.handle.net/10362/53496.
- FRANCISCO, Moisés. "Caracterização microbiológica e molecular das estirpes de Salmonella spp. isoladas em amostras clínicas, águas residuais e alimentos na região de Luanda e dos seus perfis de resistência aos antimicrobianos - o seu impacto na saúde pública.". Doutoramento, 2018. http://hdl.handle.net/10362/59484.
- THERON, Maria João de Resende. "Determinação da actividade de efluxo de Hoechst 33258 em Escherichia coli". Mestrado, 2018. http://hdl.handle.net/10362/66373.
- Antunes, Jéssica. "Estudo da contribuição de bombas de efluxo,porinas e ß-lactamases na resistência aos carbapenemos em isolados clínicos de Acinetobacter baumannii". Mestrado, 2018. http://hdl.handle.net/10362/114950.
- ANTUNES, Samuel Filipe Jesus. "Aplicação de um método fluorométrico em placa de 96 poços para a detecção de actividade de efluxo em bactérias". Mestrado, 2017. http://hdl.handle.net/10362/53802.
- GABRIEL, Marta Isabel Martins. "Resposta imunitária inflamatória de macrófagos na presença de inibidores de efluxo". Mestrado, 2016. http://hdl.handle.net/10362/19084.
- SIMÕES, Ana Sofia Mourão. "Contribuição do efluxo para a aquisição de resistência aos antibióticos em isolados clínicos de Acinetobacter baumannii". Mestrado, 2016. http://hdl.handle.net/10362/19196.
- EUSÉBIO, Ana Sofia Sancho. "Determinantes genéticos de virulência e de resistência aos antibióticos em isolados uropatogénicos de Escherichia coli provenientes da comunidade e do hospital.". Mestrado, 2015. http://hdl.handle.net/10362/19064.
- Chocalheiro, Ana Luísa Mateus. "Lab on paper: biossensores colorimétricos de papel para a detecção de membros do complexo Mycobacterium tuberculosis". Mestrado, 2014. http://hdl.handle.net/10362/13836.
- MACHADO, DIANA. "The dynamics of drug resistance in Mycobacterium tuberculosis: exploring the biological basis of multi- and extensively drug resistant tuberculosis (MDR/XDRTB) as a route for alternative therapeutic strategies". Doutoramento, 2014. https://www.authenticus.pt/P-010-V6R.
- COSTA, Pedro Miguel Nisa. "Improved nucleic acid testing strategies to detect and discriminate veterinary relevant Mycobacterium tuberculosis complex members". Doutoramento, 2014. https://www.authenticus.pt/P-010-V72.
- PINTO, Antónia Rosa Trindade. "Resistência mediada por efluxo em Escherichia coli: novas estratégias terapêuticas utilizando antibióticos e inibidores do efluxo". Mestrado, 2012. http://hdl.handle.net/10362/14014.
- Cabral, Vanessa Roque. "Pesquisa de compostos com actividade inibidora de bombas de efluxo bacterianas". Mestrado, 2012. http://hdl.handle.net/10451/11231.
- RAMOS, Jorge Alexandre Santos. "Transporte do brometo de etídio através da parede celular de Mycrobacterium smegmatis: desenvolvimento e aplicação de metodologias de quantificação do transporte e correlação com a resistência aos antibióticos". Mestrado, 2010. http://hdl.handle.net/10362/10272.
- RODRIGUES, Liliana Isabel Dias; Rodrigues, Liliana. "The role of the efflux mechanisms in multidrug resistance in Mycobacterium tuberculosis". Doutoramento, 2010. http://hdl.handle.net/10362/4813.
- MACHADO, Diana Oliveira. "Dinâmica fisiológica e mutacional da multirresistência em Mycobacterium tuberculosis". Mestrado, 2009. http://hdl.handle.net/10362/19211.
- CHAREPE, Nadia Borges. "Impacto da sobre-expressão de bombas de efluxo de estirpes E. coli MDR clínicas na resistência aos compostos antimicrobianos". Mestrado, 2008. http://hdl.handle.net/10362/19222.
- MARTINS, Marta Sofia Lopes. "The role played efflux systems on the resistance to antibiotics". Doutoramento, 2008. http://hdl.handle.net/10362/61898.
- MARTINS, Marta Sofia Lopes. "The antimycobacterial activity of thioridazine derivatives against drug resistant Mycobacterium tuberculosis: in vitro, ex vivo and in vivo studies". Doutoramento, 2008. https://www.authenticus.pt/P-010-V70.
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