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Joana holds a BSc degree in Genetics and Biotechnology (UTAD, 2014), an MSc degree in Molecular Genetics (CBMA-UM, 2017), and a Ph.D. degree in Molecular and Environmental Biology (CBMA-UM and CIMA-UNAV, 2022). During her BSc degree, she did an internship in the Laboratory of Molecular Genetics (INIAV - Oeiras), which was crucial to developing her bachelor's project, involving the genotyping of cereals with high carotenoid content. Her master thesis, developed at CBMA and CEB, allowed her to elucidate the molecular mechanism underlying the anticancer activity of the natural protein lactoferrin and, ultimately, unravel its molecular/cellular target(s). During her Ph.D. degree, Joana had the opportunity to work at CIMA in the University of Navarra, Pamplona for almost two years. Her Ph.D. thesis highlighted the role of the N-terminal acetylation and the N-degron pathways on apoptosis regulation. These works resulted in several poster presentations at national and international congresses and oral presentations as well as in four scientific papers, one manuscript, and one review in preparation. By working with different cell models (plants, mammalian/mouse, and yeast cells), she has gathered experience and know-how in genetics, molecular biology, cell biology, and microbiology. After completion of her Ph.D., Joana was awarded a master's fellowship and she has been working on the WINE-TUNNING (EXPL/BAA-AGR/1096/2021) project, which aims to identify novel yeast strains and methods to overcome emergent challenges in wine production. During this time, she has attended different training courses and workshops, and scientific meetings and participated in and organized several science communication programs. Since September 2023, Joana has been working as a post-doc researcher in an ERC project named "BeTASTy – New Molecular and Cell-based Approaches to assess Food Astringency and Bitterness" at REQUIMTE - FCUP.
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Identificação

Identificação pessoal

Nome completo
Joana Catarina Pereira Guedes

Nomes de citação

  • Joana P. Guedes

Identificadores de autor

Ciência ID
8A1F-EEAF-7FC8
ORCID iD
0000-0002-3265-5357

Telefones

Telefone
  • 253604314 (Profissional)

Moradas

  • Centro de Biologia Molecular e Ambiental - Universidade do Minho. Campus de Gualtar, 4710-057, Gualtar - Braga, Braga, Portugal (Profissional)

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador independente (B1) Utilizador proficiente (C1) Utilizador independente (B1) Utilizador independente (B1)
Espanhol; Castelhano Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2)
Formação
Grau Classificação
2017 - 2022
Concluído
 Biologia Molecular e Ambiental (Doutoramento)
Especialização em Especialidade: Biologia Celular e Saúde
Universidade do Minho, Portugal
"“Studies on apoptosis regulation: the role of N-terminal acetylation and the N-degron pathways" (TESE/DISSERTAÇÃO)
 Muito bom com distinção
2018/07/02 - 2018/07/13
Concluído
 Degradação e Tráfego de Proteínas na Saúde e na Doença (Outros)
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
 19
2018/06/04 - 2018/06/15
Concluído
 Engenharia Metabólica (Outros)
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
2014/10 - 2017/03
Concluído
 Genética Molecular (Mestrado)
Universidade do Minho Escola de Ciências, Portugal
"Molecular mechanism underlying the anticancer activity of Lactoferrin in highly metastatic cancer cell lines" (TESE/DISSERTAÇÃO)
 18
2017
Concluído
 Genética Molecular (Mestrado)
Especialização em Sem especialização
Universidade do Minho, Portugal
"Molecular Mechanisms Underlying the Anticancer Activity of Lactoferrin in Highly Metastatic Cancer Cell Lines" (TESE/DISSERTAÇÃO)
 19
2015/06/22 - 2015/07/04
Concluído
 Mammalian and yeast cells as models in programmend cell death (Outros)
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
 18
2015/06/08 - 2015/06/19
Concluído
 Cancer therapy: from basic research to clinic (Outros)
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
 19
2015/04 - 2015/04
Concluído
 Advances in Plant Molecular Biology (Outros)
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
 16
2011/09 - 2014/07
Concluído
 Genética e Biotencologia (Licenciatura)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
"Genotipagem de cereais com elevado teor de carotenoides utilizando um marcador funcional STS" (TESE/DISSERTAÇÃO)
 15
2013/07/01 - 2013/07/31
Concluído
 Estágio de Investigação (Outros)
Especialização em Biologia Molecular
Instituto Nacional de Investigação Agrária e Veterinária, Portugal
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2023/09/15 - Atual Investigador Contratado (Investigação) REQUIMTE LAQV Porto, Portugal
Universidade do Porto Faculdade de Ciências, Portugal
Projetos

Bolsa

Designação Financiadores
2017/10/01 - Atual Unveiling a new Bax regulation mechanism by NatB-mediated N-terminal acetylation
SFRH/BD/132070/2017
Bolseiro de Doutoramento
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal

Centro de Investigación Médica Aplicada, Espanha
Em curso
2021/12/01 - 2022/01/31 Unveiling a new Bax regulation mechanism by NatB-mediated N-terminal acetylation
COVID/BD/151956/2021
 Fundação para a Ciência e a Tecnologia
Concluído
2021/12/01 - 2022/01/31 Unveiling a new Bax regulation mechanism by NatB-mediated N-terminal acetylation
COVID/BD/151956/2021
10.54499/COVID/BD/151956/2021
Universidade do Minho Escola de Ciências, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2017/10/01 - 2021/11/30 Unveiling a new Bax regulation mechanism by NatB-mediated N-terminal acetylation
SFRH/BD/132070/2017
Universidade do Minho Escola de Ciências, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído

Projeto

Designação Financiadores
2022/04/11 - 2023/04/11 WINETUNING: Novel strains and methods to overcome emergent challenges in wine production
EXPL/BIA-MIC/5246/2020
Bolseiro de Investigação
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2019/01/01 - 2019/12/31 CENTRO DE BIOLOGIA MOLECULAR E AMBIENTAL
UID/BIA/04050/2019
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal

Universidade do Minho, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2019/01/01 - 2019/12/31 CENTRO DE BIOLOGIA MOLECULAR E AMBIENTAL
UID/BIA/04050/2019
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal

Universidade do Minho, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2015 - 2017 UID/BIA/04050/2013 (POCI-01-0145-FEDER-007569)
UID/BIA/04050/2013
Outra
Fundação para a Ciência e a Tecnologia
Concluído
2015 - 2017 Strategic funding 2015-2018
UID/BIO/04469/2013 (POCI-01-0145-FEDER-006684)
Outra
Universidade do Minho, Portugal
 Fundação para a Ciência e a Tecnologia

Governo da República Portuguesa
Concluído
2015 - 2017 Fun-Silk: Functionalized silk-based polymers as advanced biomaterials
PEstOE/BIA/UI4050/2014
Outra
Universidade do Minho Centro de Biologia Molecular e Ambiental
2015 - 2017 DESIGN OF NOVEL BREAST TUMOR ‘TARGETED` MULTIFUNCTIONAL NANOPARTICLES
PTDC/SAU-BMA/121028/2010
Outra
Fundação para a Ciência e a Tecnologia
Concluído
2015 - 2016 RECI/BBB-EBI/0179/2012 (FCOMP-01-0124-FEDER-027462)
RECI/BBB-EBI/0179/2012 (FCOMP-01-0124-FEDER-027462)
Outra
2013/04/01 - 2016 Phosphoregulation of Bax-dependent cell death
FCT-ANR/BEX-BCM/0175/2012
Outra
Universidade do Minho, Portugal
 Fundação para a Ciência e a Tecnologia

Agence nationale de la recherche
Concluído
Produções

Publicações

Artigo em conferência
  1. Pereira, Cátia S.; Guedes, Joana P.; Chaves, Susana R.; Gerós, Hernâni; Rodrigues, L. R.; Côrte-Real, Manuela. "How can a milk protein selectively kill cancer cells? Mechanisms underlying lactoferrin-induced apoptosis". 2019.
  2. Pereira, Cátia S.; Guedes, Joana P.; Chaves, Susana R.; Gerós, Hernâni; Rodrigues, L. R.; Côrte-Real, Manuela. "How can a milk protein selectively kill cancer cells? Mechanisms underlying lactoferrin-induced apoptosis". 2019.
  3. Pereira, Cátia Sofia Santos; Guedes, Joana P.; Chaves, Susana Alexandra Rodrigues; Andrés, María T.; Fierro, José F.; Gerós, H.; Rodrigues, L. R.; Côrte-Real, Manuela. "Deciphering the mechanisms underlying bovine milk lactoferrin anticancer activity using yeast and cancer cell lines as complementary models". 2018.
  4. Pereira, Cátia Sofia Santos; Guedes, Joana P.; Chaves, Susana Alexandra Rodrigues; Andrés, María T.; Fierro, José F.; Gerós, H.; Rodrigues, L. R.; Côrte-Real, Manuela. "Deciphering the mechanisms underlying bovine milk lactoferrin anticancer activity using yeast and cancer cell lines as complementary models". 2018.
  5. Pereira, Cátia Sofia Santos; Guedes, Joana P.; Chaves, Susana R.; Gerós, H.; Rodrigues, L. R.; Côrte-Real, Manuela. "Exploring a novel effect of lactoferrin on the plasma membrane towards the elucidation of the mechanisms of action: from yeast to human cells". 2017.
  6. Pereira, Cátia Sofia Santos; Guedes, Joana P.; Chaves, Susana R.; Gerós, H.; Rodrigues, L. R.; Côrte-Real, Manuela. "Exploring a novel effect of lactoferrin on the plasma membrane towards the elucidation of the mechanisms of action: from yeast to human cells". 2017.
Artigo em revista
  1. Soares, Susana; Guerreiro, Carlos; Vilaça, Rita; Joana P. Guedes; Fernandes, Andreia. Autor correspondente: Soares, Susana. "New molecular and cell-based approaches to assess food astringency and bitterness". The Project Repository Journal 21 1 (2024): 134-137. https://doi.org/10.54050/prj2122280.
    10.54050/prj2122280
  2. Joana P. Guedes; Cardoso, Tiago Vidal; Fernandes, Ticiana; Mendes, Filipa; Baleiras-Couto, M. Margarida; Duarte, Filomena L.; Sousa, Maria João; et al. "Exploring wine yeast natural biodiversity to select strains with enological traits adapted to climate change". Heliyon 10 18 (2024): e36975. https://doi.org/10.1016/j.heliyon.2024.e36975.
    10.1016/j.heliyon.2024.e36975
  3. Guedes, Joana P.; Boyer, Jean Baptiste; Elurbide, Jasmine; Carte, Beatriz; Redeker, Virginie; Sago, Laila; Meinnel, Thierry; et al. "NatB Protects Procaspase-8 from UBR4-Mediated Degradation and Is Required for Full Induction of the Extrinsic Apoptosis Pathway". Molecular and Cellular Biology 44 9 (2024): 358-371. https://doi.org/10.1080/10985549.2024.2382453.
    10.1080/10985549.2024.2382453
  4. Jasmin Elurbide Tardio; Beatriz Carte; Joana P. Guedes; Rafael Aldabe. "NatB Catalytic Subunit Depletion Disrupts DNA Replication Initiation Leading to Senescence in MEFs". International Journal of Molecular Sciences (2023): https://www.mdpi.com/1422-0067/24/10/8724.
    10.3390/ijms24108724
  5. Santos-Pereira, Cátia; Guedes, Joana P.; Ferreira, Débora; Rodrigues, Lígia R.; Côrte-Real, Manuela. "Lactoferrin perturbs intracellular trafficking, disrupts cholesterol-rich lipid rafts and inhibits glycolysis of highly metastatic cancer cells harbouring plasmalemmal V-ATPase". International Journal of Biological Macromolecules 220 (2022): 1589-1604. http://dx.doi.org/10.1016/j.ijbiomac.2022.09.120.
    10.1016/j.ijbiomac.2022.09.120
  6. Guedes, Joana P.; Baptista, Vitória; Cátia S. Pereira; Sousa, Maria João; Manon, Stéphen; Chaves, Susana R.; Côrte-Real, Manuela. "Acetic acid triggers cytochrome c release in yeast heterologously expressing human Bax". (2022): https://hdl.handle.net/1822/77167.
    10.1007/s10495-022-01717-0
  7. Guedes, Joana P.; Baptista, Vitória; Cátia S. Pereira; Sousa, Maria João; Manon, Stéphen; Chaves, Susana R.; Côrte-Real, Manuela. "Acetic acid triggers cytochrome c release in yeast heterologously expressing human Bax". (2022): https://hdl.handle.net/1822/77167.
    10.1007/s10495-022-01717-0
  8. Guedes, Joana P.; Pereira, Cátia S.; Rodrigues, Lígia R.; Côrte-Real, Manuela. "Bovine Milk Lactoferrin Selectively Kills Highly Metastatic Prostate Cancer PC-3 and Osteosarcoma MG-63 Cells In Vitro". Frontiers in Oncology 8 (2018): http://dx.doi.org/10.3389/fonc.2018.00200.
    Acesso aberto • Publicado
  9. Guedes, Joana P.; Pereira, Cátia Sofia Santos; Rodrigues, L. R.; Côrte-Real, Manuela. "Bovine milk lactoferrin selectively kills highly metastatic prostate cancer PC-3 and osteosarcoma MG-63 cells in vitro". (2018): http://hdl.handle.net/1822/54977.
    10.3389/fonc.2018.00200
  10. Guedes, Joana P.; Pereira, Cátia Sofia Santos; Rodrigues, L. R.; Côrte-Real, Manuela. "Bovine milk lactoferrin selectively kills highly metastatic prostate cancer PC-3 and osteosarcoma MG-63 cells in vitro". (2018): http://hdl.handle.net/1822/54977.
    10.3389/fonc.2018.00200
  11. Pereira, Cátia S.; Guedes, Joana P.; Gonçalves, Marília; Loureiro, Luís; Castro, Lisandra; Gerós, Hernâni; Rodrigues, Lígia R.; Côrte-Real, Manuela. "Lactoferrin selectively triggers apoptosis in highly metastatic breast cancer cells through inhibition of plasmalemmal V-H+-ATPase". Oncotarget 7 38 (2016): http://dx.doi.org/10.18632/oncotarget.11394.
    Publicado • 10.18632/oncotarget.11394
Poster em conferência
  1. Joana P. Guedes; Machado Beatriz; Mendes, Filipa; Manon Stéphen; CHAVES, SUSANA; Côrte-Real, Manuela. "NatB regulates Bax-induced cell death in a heterologous expression model system". Trabalho apresentado em I CBMA Open Day & II PhD|Bio Symposium, 2024.
  2. Mendes, Filipa; Fonseca Carolina; Joana P. Guedes; Sousa, Maria João; CHAVES, SUSANA; Côrte-Real, Manuela. "Zygosaccharomyces parabailii can reduce volatile acidity of acidic wines". Trabalho apresentado em I CBMA Open Day & II PhD|Bio Symposium, 2024.
  3. Joana P. Guedes; Cardoso Tiago; Mendes, Filipa; Fernandes, Ticiana; Ricardo Franco-Duarte; Baleiras-Couto Margarida; Duarte Filomena; et al. "Exploring wine yeast natural biodiversity to select strains with enological traits adapted to climate change". Trabalho apresentado em 31st International Conference on Yeast Genetics and Molecular Biology, 2023.
  4. Mendes, Filipa; Joana P. Guedes; Cardoso Tiago; Sousa, Maria João; Côrte-Real, Manuela; CHAVES, SUSANA. "Bio-reduction of wine volatile acidity using yeast cells". Trabalho apresentado em 31st International Conference on Yeast Genetics and Molecular Biology, 2023.
  5. Mendes, Filipa; Joana P. Guedes; Baleiras-Couto Margarida; Duarte Filomena; Sousa, Maria João; CHAVES, SUSANA; Côrte-Real, Manuela. "Recovery of acidic wines through bio-reduction of their volatile acidity using yeast cells". Trabalho apresentado em MicroSummit 2022, 2022.
  6. Vitória Baptista; Joana P. Guedes; Cátia Santos-Pereira; Maria João Sousa; Stéphen Manon; Susana Chaves; Manuela Côrte-Real. "Acetic acid as a trigger to activate human Bax heterologously expressed in yeast". Trabalho apresentado em ICY15 meets ICYGMB30, Vienna, Austria, 2021.
  7. Cátia Santos-Pereira; Joana P. Guedes; Hernâni Gerós; Lígia Rodrigues; Manuela Côrte-Real. "Lactoferrin is selectively cytotoxic for highly metastatic cancer cells by inhibiting plasmalemmal V-ATPase". Trabalho apresentado em 14th International Conference on Lactoferrin Structure, Function and Applications, Lima, Peru, 2019.
  8. Pereira, Cátia S.; Guedes, Joana; Chaves, Susana R.; Gerós, Hernâni; Rodrigues, Lígia R.; Côrte-Real, Manuela. "The role of membrane lipid domains on lactoferrin anticancer activity: from yeast to human cells". Trabalho apresentado em FEBS-EMBO lecture course: Molecular Organization, Function and Dynamics of Biomembranes, 2019.
  9. Pereira, Cátia S.; Guedes, Joana; Chaves, Susana R.; Gerós, Hernâni; Rodrigues, Lígia R.; Côrte-Real, Manuela. "The role of membrane lipid domains on lactoferrin anticancer activity: from yeast to human cells". Trabalho apresentado em EMBO course Caveolae and nanodomains: Translating structural principles and dynamics into function, 2019.
  10. Vitória Baptista; Cátia Santos-Pereira; Joana P. Guedes; Maria João Sousa; Susana Chaves; Manuela Côrte-Real. "Yeast cells expressing human Bax as a tool to study its activation and regulation". Trabalho apresentado em I Jornadas da Ciência: Concentra o conhecimento, Braga, Portugal, 2019.
  11. Pereira, Cátia S.; Guedes, Joana; Chaves, Susana R.; Gerós, Hernâni; Rodrigues, Lígia R.; Côrte-Real, Manuela. "Studying the effect of bovine milk lactoferrin on the plasma membrane of yeast and human cells". Trabalho apresentado em IV SYMPOSIUM OF THE DOCTORAL PROGRAM IN APPLIED AND ENVIRONMENTAL BIOLOGY, 2018.
  12. Guedes, Joana; Pereira, Cátia S.; Rodrigues, Lígia R.; Côrte-Real, Manuela. "The highly metastatic prostate cancer PC-3 and osteosarcoma MG-63 cell lines are sensitive to bovine lactoferrin". Trabalho apresentado em IV SYMPOSIUM OF THE DOCTORAL PROGRAM IN APPLIED AND ENVIRONMENTAL BIOLOGY, 2018.
  13. Baptista, Vitória; Pereira, Cátia S.; Guedes, Joana; Sousa, Maria João; Chaves, Susana R.; Côrte-Real, Manuela. "The yeast Saccharomyces cerevisiae as a model organism to exploit the regulation of the human pro-apoptotic protein Bax". Trabalho apresentado em IV SYMPOSIUM OF THE DOCTORAL PROGRAM IN APPLIED AND ENVIRONMENTAL BIOLOGY, 2018.
    Pessoal de suporte
  14. Vitória Baptista; Cátia Santos-Pereira; Joana P. Guedes; Maria João Sousa; Susana Chaves; Manuela Côrte-Real. "Yeast Saccharomyces cerevisiae as a model organism to exploit the regulation of the human pro-apoptotic protein Bax". Trabalho apresentado em 4th symposium of PDBMA (Doctoral Program in Applied and Environmental Biology), Braga, Portugal, 2018.
  15. Pereira, Cátia S.; Guedes, Joana; Chaves, Susana R.; Gerós, Hernâni; Rodrigues, Lígia R.; Côrte-Real, Manuela. "How can a milk protein selectively kill cancer cells? Mechanisms underlying lactoferrin-induced apoptosis". Trabalho apresentado em 26th Euroconference on Apoptosis: Cell death in disease: from small molecules to translational medicine, 2018.
  16. Pereira, Cátia S.; Guedes, Joana; Chaves, Susana R.; Gerós, Hernâni; Rodrigues, Lígia R.; Côrte-Real, Manuela. ""Lactoferrin perturbs intracellular trafficking in yeast and highly metastatic cancer cells". Trabalho apresentado em 2nd Small Meeting on Endocytic Trafficking and Signalling (SMETS2), 2018.
  17. Pereira, Cátia S.; Guedes, Joana; Chaves, Susana R.; Fierro, JF; Andrés, MT; Gerós, Hernâni; Rodrigues, Lígia R.; Côrte-Real, Manuela. "Deciphering the mechanisms underlying bovine milk lactoferrin anticancer activity using yeast and cancer cell lines as complementary models". Trabalho apresentado em Jornadas de Biologia de Leveduras “XXI Professor van Uden, 2018.
  18. Baptista, Vitória; Pereira, Cátia S.; Guedes, Joana; Sousa, Maria João; Chaves, Susana R.; Côrte-Real, Manuela. "Yeast as a cell model to study the human pro-apoptotic protein Bax". Trabalho apresentado em Jornadas de Biologia de Leveduras “XXI Professor van Uden, 2018.
    Pessoal de suporte
  19. Pereira, Cátia S.; Guedes, Joana; Chaves, Susana R.; Gerós, Hernâni; Rodrigues, Lígia R.; Côrte-Real, Manuela. "Exploring a novel effec of lactoferrin on the plasma membrane towards the elucidation of the mechanisms of action: from yeast to human cells". Trabalho apresentado em Jornadas de Bioquímica – Da investigação à indústria, 2018.
  20. Baptista, Vitória; Pereira, Cátia S.; Guedes, Joana; Sousa, Maria João; Chaves, Susana R.; Côrte-Real, Manuela. "Yeast as a cell model to study the human pro-apoptotic protein Bax". Trabalho apresentado em Jornadas de Bioquímica – Da investigação à indústria, 2018.
    Pessoal de suporte
  21. Pereira, Cátia S.; Guedes, Joana; Chaves, Susana R.; Gerós, Hernâni; Rodrigues, Lígia R.; Côrte-Real, Manuela. "Lactoferrin perturbs intracellular trafficking in yeast and highly metastatic cancer cells". Trabalho apresentado em 1st Meeting on Vesicular Biology, 2018.
  22. Pereira, Cátia S.; Guedes, Joana; Chaves, Susana R.; Gerós, Hernâni; Rodrigues, Lígia R.; Côrte-Real, Manuela. "Exploring a novel effec of lactoferrin on the plasma membrane towards the elucidation of the mechanisms of action: from yeast to human cells". Trabalho apresentado em Microbiotec 17, 2017.
  23. Guedes, Joana; Pereira, Cátia S.; Rodrigues, Lígia R.; Côrte-Real, Manuela. "Insights on the molecular mechanisms underlying the anticancer activity of lactoferrin in highly metastatic cancer cell lines". Trabalho apresentado em XIX National Congress of Biochemistry, 2016.
  24. Pereira, Cátia S.; Guedes, Joana; Gonçalves, Marília; Loureiro, Luís; Castro, Lisandra; Gerós, Hernâni; Rodrigues, Lígia R.; Côrte-Real, Manuela. "Lactoferrin selectively triggers apoptosis in highly metastatic breast cancer cells through inhibition of plasmalemmal V-H+ATPase". Trabalho apresentado em XIX National Congress of Biochemistry, 2016.
  25. Pereira, Cátia S.; Guedes, Joana; Gonçalves, Marília; Loureiro, Luís; Castro, Lisandra; Gerós, Hernâni; Rodrigues, Lígia R.; Côrte-Real, Manuela. "Lactoferrin selectively triggers apoptosis in highly metastatic breast cancer cells through inhibition of plasmalemmal V-H+ATPase". Trabalho apresentado em 24th Congress of the European Cell Death Organization – “Cell Death in Health and Disease”, 2016.
Tese / Dissertação
  1. Guedes, Joana. "Molecular mechanisms underlying the anticancer activity of lactoferrin in highly metastatic cancer cell lines". Mestrado, Universidade do Minho Centro de Biologia Molecular e Ambiental, 2017. http://hdl.handle.net/1822/45646.
  2. Guedes, Joana. "Genotipagem de cereais com elevado teor de carotenoides utilizando um marcador funcional STS". 2014.
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2019/11 Lactoferrin is selectively cytotoxic for highly metastatic cancer cells by inhibiting plasmalemmal V-ATPase International Conference on Lactoferrin Structure, Function and Applications
(Lima, Peru)
2018/09 How can a milk protein selectively kill cancer cells? Mechanisms underlying lactoferrin-induced apoptosis 26th Euroconference on Apoptosis: Cell death in disease: from small molecules to translational medicine
(Saint Petersburg, Rússia)
2018/06 Deciphering the mechanisms underlying bovine milk lactoferrin anticancer activity using yeast and cancer cell lines as complementary models XXI Jornadas de Biologia de Leveduras “Professor van Uden
(Braga, Portugal)
2017/09 Molecular mechanism underlying the anticancer activity of Lactoferrin in highly metastatic cancer cell lines 2nd Joint Workshop of the PhD Programs in Applied and Environmental Microbiology (DP_AEM) and Molecular and Environmental Biology (PDBMA)
(Braga, Portugal)
2017/05 Mechanistic insights on the selective anticancer activity of lactoferrin unveiled by yeast 12th International Meeting on Yeast Apoptosis
(Bari, Itália)
2017/05 Understanding the interplay between the pro-apoptotic protein lactoferrin and biomembranes: from yeast to human cells 12th International Meeting on Yeast Apoptosis
(Bari, Itália)

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação) 		Instituição / Organização
2018 - 2018 Technical and Scientific Assistant in the laboratory classes of the advanced course “Mammalian and Yeast as Complementary Cell Models in Programmed Cell Death and Autophagy” (2018 - 2018)
Outro (Outra)
 Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
2017 - 2017 Technical and Scientific Assistant in the laboratory classes of the “Functional and Cellular Biology” course of the Masters in Molecular Genetics and Masters in Biophysics and Bionanosystems (2017 - 2017)
Outro (Outra)
 Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
2017 - 2017 Technical and Scientific Assistant in the laboratory classes of the advanced course “Mammalian and Yeast as Complementary Cell Models in Programmed Cell Death and Autophagy” (2017 - 2017)
Outro (Outra)
 Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
2013/03 - 2014/03 VI National Journeys of Genetics and Biotechnology and National Meeting of Biotechnology Students (2013/03 - 2014/03)
Congresso (Membro da Comissão Organizadora)
 Universidade de Trás-os-Montes e Alto Douro, Portugal
2013 - 2014 Solidarity Lectures (2013 - 2014)
Seminário (Membro da Comissão Organizadora)
 Universidade de Trás-os-Montes e Alto Douro, Portugal
2013 - 2014 2nd Genetics and Biotechnology Lectures (2013 - 2014)
Conferência (Membro da Comissão Organizadora)
 Universidade de Trás-os-Montes Centro de Estudos Transdisciplinares para o Desenvolvimento, Portugal

Participação em evento

Descrição da atividade
Tipo de evento 		Nome do evento
Instituição / Organização
2018/10/15 - 2018/10/17 Visionaries from around the world came together to share, interact and collaborate with scientists, business experts, entrepreneurs, artists, changemakers and innovators.
Conferência
 INL SUMMIT| Nanotecnology: An enabler for the new economy
International Iberian Nanotechnology Laboratory, Portugal
2018/10 - 2018/10 In this symposium there are presentations of the work developed in the CBMA (Center for Molecular and Environmental Biology) within the scope of the doctoral program of molecular and environmental biology, as well as lectures by invited researchers.
Simpósio
 IV Symposium of the PhD Programme on Molecular and Environmental Biology
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
2018/03/08 - 2018/03/08 Mesa redonda que tem como objectivo elucidar atuais alunos de Genética e Biotecnologia sobre o percurso de ex-alunos de licenciatura.
Mesa-redonda
 X Jornadas de Genética e Biotecnologia
Universidade de Trás-os-Montes e Alto Douro, Portugal
2017/09/25 - 2017/09/27 In this workshop there is a presentation of the work developed in the CBMA (Center for Molecular and Environmental Biology) within the scope of the PhD Programs in Applied and Environmental Microbiology (DP_AEM) and Molecular and Environmental Biology (PDBMA), as well as lectures by invited researchers.
Oficina (workshop)
 2ND Joint Workshop of the PhD Programs in Applied and Environmental Microbiology (DP_AEM) and Molecular and Environmental Biology (PDBMA)
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
2015/11 - 2015/11 This symposium included presentations of work developed at CBMA (Center for Molecular and Environmental Biology) within the scope of the doctoral program of molecular and environmental biology, as well as lectures by invited researchers.
Simpósio
 III Symposium of the PhD Programme on Molecular and Environmental Biology
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
2014/11 - 2014/11 In this symposium, the work developed in the CBMA (Center for Molecular and Environmental Biology) within the scope of the doctoral program of molecular and environmental biology, as well as lectures by invited researchers, were presented.
Simpósio
 II Symposium of the PhD Programme on Molecular and Environmental Biology
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
2013/10/23 - 2013/10/23 Lecture about Pharmacological Investigation
Seminário
 IV Forum of Pharmacological Investigation - New Challenges in health
Universidade de Trás-os-Montes e Alto Douro, Portugal
2013/02/20 - 2013/02/22 This congress included presentations of work developed at UTAD, as well as lectures by invited researchers.
Congresso
 V National Journeys of Genetics and Biotechnology
Universidade de Trás-os-Montes e Alto Douro, Portugal
2012/03/01 - 2012/03/03 This congress included presentations of work developed at UTAD, as well as lectures by invited researchers.
Congresso
 IV National Journeys of Genetics and Biotechnology
Universidade de Trás-os-Montes e Alto Douro, Portugal

Membro de associação

Nome da associação Tipo de participação
2013 - 2014 Núcleo de Estudantes de Genética e Biotecnologia (ADNGB) Tesoureira