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My scientific career has evolved from foundational work in experimental biomedicine to a broader mission of strengthening transparency, reproducibility, and research data management across the life sciences. I began as a biochemist and cell biologist at the University of Coimbra, where I later completed my PhD in Cell Biology. During these early years, my research centered on mitochondrial physiology and toxicology, exploring how cells respond to metabolic stress and dysfunction. This period grounded me in rigorous experimental design and cultivated a deep appreciation for methodological precision. As my work progressed, I became increasingly aware of the structural challenges that limit the reliability and reuse of biomedical research—particularly the gaps in documentation, metadata, and data stewardship. This recognition progressively shifted my trajectory toward metascience, where I now focus on developing practical approaches that help experimental researchers adopt more transparent and reproducible workflows. Over time, I expanded my expertise to include computational biology, data science, and research-quality assessment. I began integrating automated screening tools, dashboarding, and workflow design into my research practice, bridging experimental and computational perspectives. My recent publication in Physiological Reviews reflects this evolution, translating best practices in data management and sharing into accessible, actionable guidance for laboratory scientists. Today, my work combines method development, institutional capacity building, and community engagement. I contribute to initiatives that enhance data stewardship, support experimental design, and promote FAIR and Open Science principles. I regularly collaborate with national and international networks, mentor early-career researchers, and develop resources that help laboratories implement more robust and trustworthy research practices. Through this interdisciplinary path—spanning bench science, computational methods, and research integrity—I remain committed to improving the quality, transparency, and long-term value of biomedical research. --------------------------------------------------------------------------------------------------------------------------- CAREER GOALS Modern science has evidently contributed to the improvement of human living conditions. However, most of its advances often struggle to reach society, either in the form of tangible benefits or general knowledge. Several factors can contribute to this, including the lack of systematization of scientific practices, which would allow data generated by some, often with public funding, to be used (or validated) by others, namely for different purposes than initially intended. As I know from personal experience, doing science at the bench is demanding work. It requires a lot of concentration, many hours and sacrifices. However, beyond what they already do, scientists need to start documenting more of what they do, why they do it, when they do it, and how they do it, so that the information they generate can be transparent, repeatable, and used by other scientists. This process needs to be made simple and uniform. My main goals are to raise awareness and increase literacy among experimental researchers about this need and to co-develop and validate guidelines and workflows, along with experimental researchers, so that best research practices can be adopted by all.
Identificação

Identificação pessoal

Nome completo
MARIA TERESA MARTINS DA CUNHA OLIVEIRA

Identificadores de autor

Ciência ID
7F1D-6E9A-C5EA
ORCID iD
0000-0002-7382-0339
Google Scholar ID
7h2nOmwAAAAJ
Researcher Id
A-3054-2009
Scopus Author Id
9744915800

Moradas

  • Centro de Neurociências e Biologia Celular da Universidade de Coimbra. MitoXT, UC-Biotech, Biocant Park, 3060-197, Cantanhede, Cantanhede, Portugal (Profissional)

Domínios de atuação

  • Ciências Naturais - Ciências Biológicas
  • Ciências Médicas e da Saúde - Medicina Básica
  • Ciências Médicas e da Saúde - Biotecnologia Médica
  • Ciências Médicas e da Saúde - Ciências da Saúde
  • Ciências Médicas e da Saúde - Medicina Básica
  • Ciências Médicas e da Saúde - Medicina Básica

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Formação
Grau Classificação
2007/12/01 - 2018/07/04
Concluído
Post-Doc (Pós-doutoramento)
Centro de Neurociências e Biologia Celular da Universidade de Coimbra, Portugal
2008 - 2008
Concluído
Experimentação Animal- FELASA C Accreditation (Pós-Graduação)
Centro de Neurociências e Biologia Celular da Universidade de Coimbra, Portugal

Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
Approved
2007/11/07
Concluído
Biologia (Doutoramento)
Especialização em Especialidade: Biologia Celular
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Neuronal Dysfunction Induced by Drugs of Abuse" (TESE/DISSERTAÇÃO)
Approved by Unanimity with Distinction (Maximum Grade)
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento
Empregador
2024/09/01 - 2027/08/31 Investigador Contratado (Investigação) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2019/02/01 - 2024/08/31 Investigador Contratado (Investigação) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Centro de Neurociências e Biologia Celular da Universidade de Coimbra, Portugal
2019/02/01 - 2022/01/31 Investigador Contratado (Investigação) Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Outros

Categoria Profissional
Instituição de acolhimento
Empregador
2018/07/06 - 2021/11/05 Principal Investigator of Grant POCI-01-0145-FEDER-029297 Fundação para a Ciência e a Tecnologia, Portugal
Centro de Neurociências e Biologia Celular da Universidade de Coimbra, Portugal
2016/11/01 - 2018/07/31 Head of MitoXT Service Facility Centro de Neurociências e Biologia Celular da Universidade de Coimbra, Portugal
Centro de Neurociências e Biologia Celular da Universidade de Coimbra, Portugal
2008/07/01 - 2010/08/31 Principal Investigator of Grant III/34/2008 Instituto de Investigação Interdisciplinar, Universidade de Coimbra, Portugal
Centro de Neurociências e Biologia Celular da Universidade de Coimbra, Portugal
Projetos

Bolsa

Designação Financiadores
2025/07/01 - Atual InSync - Development of a New Protective Therapy Against the Cardiac Toxicity of Anti-Cancer Treatments
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2023/03/01 - Atual EXCELScIOR: EXCELlent Science with Impact, Open and Reliable
Investigador
Universidade de Coimbra, Portugal
Horizon Europe
Em curso
2019/02/01 - 2024/08/31 MitoProfiling- Mitochondrial Health Profiling. Applications in Toxicology and Personalized Medicine
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluído

Projeto

Designação Financiadores
2023/05 - Atual PAS GRAS - De-risking metabolic, environmental and behavioral determinants of obesity in children, adolescents and young adults
Investigador
European Commission
Em curso
2021/10 - 2025/10 BenBedPhar - Bench to bedside transition for pharmacological regulation of NRF2 in noncommunicable diseases European Commission
2022/01/15 - 2025/01/14 Human Neuronal Cells Differentiated from Urine-derived Stem Cells as a Platform for Personalized Medicine in Amyotrophic Lateral Sclerosis
PTDC/BTM-ORG/0055/2021
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2022/01/01 - 2023/06/30 Role of mitochondrial-thiol homeostasis in neurodegeneration: implication for amyotrophic lateral sclerosis
EXPL/BTM-TEC/1407/2021
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2022 - 2023/06/30 Mitochondria as potential drivers of sex-specific microglia dysfunctional remodelling and anxiety caused by prenatal stress
EXPL/MED-NEU/1002/2021
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2018/07/06 - 2021/12/05 Development and validation of innovative screening methods for mitochondrial health modulators
PTDC/BTM-SAL/29297/2017
Investigador responsável
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Universidade de Coimbra, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2018/05/01 - 2021/04/30 Development of Novel Mitochondria-Targeted Antioxidants for Improving SOD1-Familial Amyotrophic Lateral Sclerosis Phenotype
PTDC/MED-FAR/29391/2017
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Universidade do Porto, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2008/09 - 2010/08 Relationship Between Body Weight and the Development of Heroin Addiction: Role of Insulin and Leptin Hypothalamic Signalling Pathways
III/34/2008
Investigador responsável
Instituto de Investigação Interdisciplinar, Universidade de Coimbra
Produções

Publicações

Artigo em conferência
  1. *# Cunha-Oliveira, T. (7F1D-6E9A-C5EA). "Good practices with experimental data". Trabalho apresentado em 55th Annual Meeting of the European Society for Clinical Investigation, 2021.
    Publicado
Artigo em jornal
  1. Cunha-Oliveira, T.. "Qual o efeito das drogas de abuso no cérebro?", i, 2015, http://www.cienciaviva.pt/saberastu/.
Artigo em revista
  1. Diana Santos; Ana Burgeiro; Ana Catarina R. G. Fonseca; Cândida Dias; Teresa Cunha-Oliveira; Aryane Oliveira; João Laranjinha; et al. "Assessing the interaction of the UCP system and fatty acids on epicardial adipose tissue mitochondrial respiration". European Journal of Clinical Investigation (2025): https://doi.org/10.1111/eci.70149.
    10.1111/eci.70149
  2. Sónia A. Pinho; Cristina Barosa; Cláudia M. Deus; John G. Jones; Paulo J. Oliveira; Teresa Cunha-Oliveira. "Metabolic priming alters the morphology and metabolism of human dermal fibroblasts". EXCLI Journal; 25:Doc1419; ISSN 1611-2156 (2025): https://www.excli.de/excli/article/view/8609.
    Acesso aberto • Publicado • 10.17179/EXCLI2025-8609
  3. Sónia A. Pinho; Paulo J. Oliveira; Teresa Cunha-Oliveira. Autor correspondente: Teresa Cunha-Oliveira. "Heterogeneous redox responses in NHDF cells primed to enhance mitochondrial bioenergetics". Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease (2025): https://doi.org/10.1016/j.bbadis.2024.167495.
    Acesso aberto • Publicado • 10.1016/j.bbadis.2024.167495
  4. Cunha-Oliveira, T.; Ioannidis, John P.A.; Oliveira, Paulo J.. Autor correspondente: Cunha-Oliveira, T.. "Best Practices for Data Management and Sharing in Experimental Biomedical Research". Physiological Reviews (2024): http://dx.doi.org/10.1152/physrev.00043.2023.
    Acesso aberto • Publicado • 10.1152/physrev.00043.2023
  5. Teresa Cunha-Oliveira; Liliana Montezinho; Rui F. Simões; Marcelo Carvalho; Elisabete Ferreiro; Filomena S. G. Silva. "Mitochondria: A Promising Convergent Target for the Treatment of Amyotrophic Lateral Sclerosis". Cells (2024): https://doi.org/10.3390/cells13030248.
    10.3390/cells13030248
  6. Susana P. Pereira; Mariana S. Diniz; Ludgero C. Tavares; Teresa Cunha-Oliveira; Cun Li; Laura A. Cox; Mark J. Nijland; Peter W. Nathanielsz; Paulo J. Oliveira. "Characterizing Early Cardiac Metabolic Programming via 30% Maternal Nutrient Reduction during Fetal Development in a Non-Human Primate Model". International Journal of Molecular Sciences (2023): https://doi.org/10.3390/ijms242015192.
    10.3390/ijms242015192
  7. Pinho, S.A.; Anjo, S.I.; Cunha-Oliveira, T.. Autor correspondente: Cunha-Oliveira, T.. "Metabolic Priming as a Tool in Redox and Mitochondrial Theragnostics". Antioxidants (2023): https://www.mdpi.com/2076-3921/12/5/1072.
    Acesso aberto • Publicado • 10.3390/antiox12051072
  8. Amorim, Ricardo; Simões, Inês C.M.; Teixeira, José; Cagide, Fernando; Potes, Yaiza; Soares, Pedro; Carvalho, Adriana; et al. "Mitochondria-targeted anti-oxidant AntiOxCIN4 improved liver steatosis in Western diet-fed mice by preventing lipid accumulation due to upregulation of fatty acid oxidation, quality control mechanism and antioxidant defense systems". Redox Biology 55 (2022): 102400. http://dx.doi.org/10.1016/j.redox.2022.102400.
    Publicado • 10.1016/j.redox.2022.102400
  9. Cunha-Oliveira, Teresa; Carvalho, Marcelo; Sardão, Vilma; Ferreiro, Elisabete; Mena, Débora; Pereira, Francisco B.; Borges, Fernanda; Oliveira, Paulo J.; Silva, Filomena S. G.. Autor correspondente: Cunha-Oliveira, Teresa. "Integrative Profiling of Amyotrophic Lateral Sclerosis Lymphoblasts Identifies Unique Metabolic and Mitochondrial Disease Fingerprints". Molecular Neurobiology 59 10 (2022): 6373-6396. http://dx.doi.org/10.1007/s12035-022-02980-7.
    Publicado • 10.1007/s12035-022-02980-7
  10. Panieri, Emiliano; Pinho, Sónia A.; Afonso, Gonçalo J. M.; Oliveira, Paulo J.; Cunha-Oliveira, T.; Saso, Luciano. "NRF2 and Mitochondrial Function in Cancer and Cancer Stem Cells". Cells 11 15 (2022): 2401. http://dx.doi.org/10.3390/cells11152401.
    Acesso aberto • Publicado • 10.3390/cells11152401
  11. Cunha-Oliveira, T.; Silva, Daniela Franco; Segura, Luis; Baldeiras, Inês; Marques, Ricardo; Rosenstock, Tatiana; Oliveira, Paulo J.; Silva, Filomena S. G.. Autor correspondente: Cunha-Oliveira, T.. "Redox profiles of amyotrophic lateral sclerosis lymphoblasts with or without known SOD1 mutations". European Journal of Clinical Investigation 52 9 (2022): http://dx.doi.org/10.1111/eci.13798.
    Publicado • 10.1111/eci.13798
  12. Rui F. Simões; Paulo J. Oliveira; Teresa Cunha-Oliveira; Francisco B. Pereira. "Evaluation of 6-Hydroxydopamine and Rotenone In Vitro Neurotoxicity on Differentiated SH-SY5Y Cells Using Applied Computational Statistics". International Journal of Molecular Sciences 23 6 (2022): 3009-3009. https://doi.org/10.3390/ijms23063009.
    10.3390/ijms23063009
  13. Pinho, Sónia A.; Costa, Cláudio F.; Deus, Cláudia M.; Pinho, Sonia L.C.; Miranda-Santos, Inês; Afonso, Gonçalo; Bagshaw, Olivia; et al. "Mitochondrial and metabolic remodeling in human skin fibroblasts in response to glucose availability". The FEBS Journal (2022): http://dx.doi.org/10.1111/febs.16413.
    Publicado • 10.1111/febs.16413
  14. Cunha-Oliveira, T.; Carvalho, Marcelo; Sardão, V.; Ferreiro, Elisabete; Mena, D.; Francisco B Pereira ; Borges, Fernanda; Oliveira, P.J.; Silva, Filomena. Autor correspondente: Cunha-Oliveira, T.. "Integrative Profiling of Amyotrophic Lateral Sclerosis Lymphoblasts Identifies Unique Metabolic and Mitochondrial Disease Fingerprints". Research Square (2022): https://www.researchsquare.com/article/rs-1196454/v1.
    Acesso aberto • Em revisão • 10.21203/rs.3.rs-1196454/v1
  15. Rui F. Simões; Rute Pino; Maurício Moreira-Soares; Jaromira Kovarova; Jiri Neuzil; Rui Travasso; Paulo J. Oliveira; Teresa Cunha-Oliveira; Francisco B. Pereira. "Quantitative analysis of neuronal mitochondrial movement reveals patterns resulting from neurotoxicity of rotenone and 6-hydroxydopamine". The FASEB Journal 35 12 (2021): https://doi.org/10.1096/fj.202100899R.
    10.1096/fj.202100899R
  16. Deus, Cláudia M.; Pereira, Susana P.; Cunha-Oliveira, Teresa; Teixeira, José; Simões, Rui F.; Cagide, Fernando; Benfeito, Sofia; et al. "A mitochondria-targeted caffeic acid derivative reverts cellular and mitochondrial defects in human skin fibroblasts from male sporadic Parkinson's disease patients". Redox Biology (2021): 102037. http://dx.doi.org/10.1016/j.redox.2021.102037.
    Acesso aberto • Publicado • 10.1016/j.redox.2021.102037
  17. Pereira, Susana P.; Tavares, Ludgero C.; Duarte, Ana I.; Baldeiras, Inês; Cunha-Oliveira, Teresa; Martins, João D.; Santos, Maria S.; et al. "Sex-dependent vulnerability of fetal nonhuman primate cardiac mitochondria to moderate maternal nutrient reduction". Clinical Science 135 9 (2021): 1103-1126. http://dx.doi.org/10.1042/cs20201339.
    Publicado • 10.1042/cs20201339
  18. Simões, Rui F.; Ferrão, Rafaela; Silva, Margarida R.; Pinho, Sonia L. C.; Ferreira, Lino; Oliveira, Paulo J.; # Cunha-Oliveira, T.. Autor correspondente: # Cunha-Oliveira, T.. "Refinement of a differentiation protocol using neuroblastoma SH-SY5Y cells for use in neurotoxicology research". Food and Chemical Toxicology (2021): 111967. https://doi.org/10.1016/j.fct.2021.111967.
    Publicado • 10.1016/j.fct.2021.111967
  19. Jacinto, Sandra; Guerreiro. Patrícia; Machado de Oliveira, Rita; Cunha-Oliveira, T.; Santos, Maria João; Grazina, Manuela; Rego, Ana Cristina; Outeiro, Tiago. "MPV17 mutations are associated with a quiescent energetic metabolic profile". Frontiers in Cellular Neuroscience (2021): https://www.frontiersin.org/articles/10.3389/fncel.2021.641264/abstract.
    Publicado
  20. Costa, C. F.; Pinho, S.A.; Pinho, S. L.; Miranda-Santos, I.; Bagshaw, O.; Stuart, J.; Oliveira, P.J.; # Cunha-Oliveira, T.. Autor correspondente: # Cunha-Oliveira, T.. "Mitochondrial and metabolic remodeling in human skin fibroblasts in response to glucose availability". BioRxiv (2021): https://www.biorxiv.org/content/10.1101/2021.02.24.432508v1.
    Acesso aberto • Publicado • 10.1101/2021.02.24.432508
  21. Cunha-Oliveira, Teresa; Montezinho, Liliana; Mendes, Catarina; Firuzi, Omidreza; Saso, Luciano; Oliveira, Paulo J.; Silva, Filomena S. G.. "Oxidative Stress in Amyotrophic Lateral Sclerosis: Pathophysiology and Opportunities for Pharmacological Intervention". Oxidative Medicine and Cellular Longevity 2020 (2020): 1-29. http://dx.doi.org/10.1155/2020/5021694.
    Publicado • 10.1155/2020/5021694
  22. Serafim, Teresa L.; * Cunha-Oliveira, Teresa; Deus, Claudia M.; Sardão, Vilma A.; Cardoso, Ines M.; Yang, Shanshan; Odhiambo, John F.; et al. "Maternal obesity in sheep impairs foetal hepatic mitochondrial respiratory chain capacity". European Journal of Clinical Investigation 51 2 (2020): http://dx.doi.org/10.1111/eci.13375.
    Publicado • 10.1111/eci.13375
  23. Deus, Cláudia M.; Pereira, Susana P.; Cunha-Oliveira, Teresa; Pereira, Francisco B.; Raimundo, Nuno; Oliveira, Paulo J.. "Mitochondrial remodeling in human skin fibroblasts from sporadic male Parkinson's disease patients uncovers metabolic and mitochondrial bioenergetic defects". Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1866 3 (2020): 165615. http://dx.doi.org/10.1016/j.bbadis.2019.165615.
    Publicado • 10.1016/j.bbadis.2019.165615
  24. Ferreira, Luciana L.; Cervantes, Marlene; Froufe, Hugo J. C.; Egas, Conceição; Cunha-Oliveira, Teresa; Sassone-Corsi, Paolo; Oliveira, Paulo J.. "Doxorubicin persistently rewires cardiac circadian homeostasis in mice". Archives of Toxicology (2019): http://dx.doi.org/10.1007/s00204-019-02626-z.
    Publicado • 10.1007/s00204-019-02626-z
  25. Ferreira, Leonardo M. R.; Cunha-Oliveira, Teresa; Sobral, Margarida C.; Abreu, Patrícia L.; Alpoim, Maria Carmen; Urbano, Ana M.. "Impact of Carcinogenic Chromium on the Cellular Response to Proteotoxic Stress". International Journal of Molecular Sciences 20 19 (2019): 4901. http://dx.doi.org/10.3390/ijms20194901.
    Publicado • 10.3390/ijms20194901
  26. Valdinocci, Dario; Simões, Rui F.; Kovarova, Jaromira; Cunha-Oliveira, Teresa; Neuzil, Jiri; Pountney, Dean L.. "Intracellular and Intercellular Mitochondrial Dynamics in Parkinson's Disease". Frontiers in Neuroscience 13 (2019): http://dx.doi.org/10.3389/fnins.2019.00930.
    Acesso aberto • 10.3389/fnins.2019.00930
  27. Bajzikova, Martina; Kovarova, Jaromira; Coelho, Ana R.; Boukalova, Stepana; Oh, Sehyun; Rohlenova, Katerina; Svec, David; et al. "Reactivation of Dihydroorotate Dehydrogenase-Driven Pyrimidine Biosynthesis Restores Tumor Growth of Respiration-Deficient Cancer Cells". Cell Metabolism 29 2 (2019): 399-416.e10. http://dx.doi.org/10.1016/j.cmet.2018.10.014.
    Publicado • 10.1016/j.cmet.2018.10.014
  28. Ferreira, Luciana L.; Cunha-Oliveira, Teresa; Veloso, Caroline D.; Costa, Cláudio F.; Wallace, Kendall B.; Oliveira, Paulo J.. "Single nanomolar doxorubicin exposure triggers compensatory mitochondrial responses in H9c2 cardiomyoblasts". Food and Chemical Toxicology 124 (2019): 450-461. http://dx.doi.org/10.1016/j.fct.2018.12.017.
    Publicado • 10.1016/j.fct.2018.12.017
  29. # Teresa Cunha-Oliveira; Luciana L. Ferreira; Ana Raquel Coelho; Cláudia M. Deus; Paulo J. Oliveira. Autor correspondente: # Teresa Cunha-Oliveira. "Doxorubicin triggers bioenergetic failure and p53 activation in mouse stem cell-derived cardiomyocytes". Toxicology and Applied Pharmacology 348 (2018): 1-13. https://doi.org/10.1016/j.taap.2018.04.009.
    Publicado • 10.1016/j.taap.2018.04.009
  30. Pereira, Susana P; Deus, Cláudia M; Serafim, Teresa L; Cunha-Oliveira, Teresa; Oliveira, Paulo J. "Metabolic and Phenotypic Characterization of Human Skin Fibroblasts After Forcing Oxidative Capacity". Toxicological Sciences 164 1 (2018): 191-204. http://dx.doi.org/10.1093/toxsci/kfy068.
    Publicado • 10.1093/toxsci/kfy068
  31. Abreu, Patrícia L.; Cunha-Oliveira, Teresa; Ferreira, Leonardo M. R.; Urbano, Ana M.. "Hexavalent chromium, a lung carcinogen, confers resistance to thermal stress and interferes with heat shock protein expression in human bronchial epithelial cells". BioMetals 31 4 (2018): 477-487. http://dx.doi.org/10.1007/s10534-018-0093-7.
    Publicado • 10.1007/s10534-018-0093-7
  32. Ferreira, André; * Cunha-Oliveira, Teresa; Simões, Rui F.; Carvalho, Filipa S.; Burgeiro, Ana; Nordgren, Kendra; Wallace, Kendall B.; Oliveira, Paulo J.. "Altered mitochondrial epigenetics associated with subchronic doxorubicin cardiotoxicity". Toxicology 390 (2017): 63-73. http://dx.doi.org/10.1016/j.tox.2017.08.011.
    Acesso aberto • Publicado • 10.1016/j.tox.2017.08.011
  33. Naia, Luana; * Cunha-Oliveira, Teresa; Rodrigues, Joana; Rosenstock, Tatiana R.; Oliveira, Ana; Ribeiro, Márcio; Carmo, Catarina; et al. "Histone Deacetylase Inhibitors Protect Against Pyruvate Dehydrogenase Dysfunction in Huntington's Disease". The Journal of Neuroscience 37 10 (2017): 2776-2794. http://dx.doi.org/10.1523/jneurosci.2006-14.2016.
    Publicado • 10.1523/JNEUROSCI.2006-14.2016
  34. Coelho, Ana R.; Martins, Tatiana R.; Couto, Renata; Deus, Cláudia; Pereira, Cláudia V.; Simões, Rui F.; Rizvanov, Albert A.; et al. "Berberine-induced cardioprotection and Sirt3 modulation in doxorubicin-treated H9c2 cardiomyoblasts". Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1863 11 (2017): 2904-2923. http://dx.doi.org/10.1016/j.bbadis.2017.07.030.
    Publicado • 10.1016/j.bbadis.2017.07.030
  35. Silva, Ana Marta; Barbosa, Inês A.; Seabra, Cátia; Beltrão, Nuno; Santos, Raquel; Vega-Naredo, Ignacio; Oliveira, Paulo J.; # Cunha-Oliveira, Teresa. Autor correspondente: # Cunha-Oliveira, Teresa. "Involvement of mitochondrial dysfunction in nefazodone-induced hepatotoxicity". Food and Chemical Toxicology 94 1 (2016): 148-158. http://dx.doi.org/10.1016/j.fct.2016.06.001.
    Publicado • 10.1016/j.fct.2016.06.001
  36. Branco, Ana F.; Ferreira, André; Simões, Rui F.; Magalhães-Novais, Sílvia; Zehowski, Cheryl; Cope, Elisabeth; Silva, Ana Marta; et al. Autor correspondente: # Cunha-Oliveira, Teresa. "Ketogenic diets: from cancer to mitochondrial diseases and beyond". European Journal of Clinical Investigation 46 3 (2016): 285-298. http://dx.doi.org/10.1111/eci.12591.
    Acesso aberto • Publicado • 10.1111/eci.12591
  37. Naia, Luana; Ferreira, I. Luísa; Cunha-Oliveira, Teresa; Duarte, Ana I.; Ribeiro, Márcio; Rosenstock, Tatiana R.; Laço, Mário N.; et al. "Activation of IGF-1 and Insulin Signaling Pathways Ameliorate Mitochondrial Function and Energy Metabolism in Huntington’s Disease Human Lymphoblasts". Molecular Neurobiology 51 1 (2015): 331-348. http://dx.doi.org/10.1007/s12035-014-8735-4.
    Publicado • 10.1007/s12035-014-8735-4
  38. Ferreira, André; Serafim, Teresa L; Sardão, Vilma A; # Cunha-Oliveira, Teresa. Autor correspondente: # Cunha-Oliveira, Teresa. "Role of mtDNA-related mitoepigenetic phenomena in cancer". European Journal of Clinical Investigation 45 S1 (2015): 44-49. http://dx.doi.org/10.1111/eci.12359.
    Acesso aberto • Publicado • 10.1111/eci.12359
  39. Moreira, Ana C; Branco, Ana F; Sampaio, Susana F; Cunha-Oliveira, Teresa; Martins, Tatiana R; Holy, Jon; Oliveira, Paulo J; et al. "Mitochondrial apoptosis-inducing factor is involved in doxorubicin-induced toxicity on H9c2 cardiomyoblasts". Biochimica et Biophysica Acta-Molecular Basis of Disease 1842 12 (2014): 2468-2478. http://hdl.handle.net/10316/41109.
    Acesso aberto • Publicado • 10.1016/j.bbadis.2014.09.015
  40. Branco, Ana F; Moreira, Ana C; Cunha-Oliveira, Teresa; Couto, Renata; Sardao, Vilma A; Rizvanov, Albert A; Palotas, Andras; et al. "ß-adrenergic over-stimulation and cardio-myocyte apoptosis: two receptors, one organelle, two fates?". Current Drug Targets 15 10 (2014): 956-964. http://dx.doi.org/10.2174/1389450115666140902124230.
    Publicado • 10.2174/1389450115666140902124230
  41. Perfeito, Rita; * Cunha-Oliveira, Teresa; Rego, Ana Cristina. "Reprint of: Revisiting oxidative stress and mitochondrial dysfunction in the pathogenesis of Parkinson disease—resemblance to the effect of amphetamine drugs of abuse". Free Radical Biology and Medicine 62 (2013): 186-201. http://dx.doi.org/10.1016/j.freeradbiomed.2013.05.042.
    Publicado • 10.1016/j.freeradbiomed.2013.05.042
  42. # Cunha-Oliveira, Teresa; Silva, Lisbeth; Silva, Ana Maria; Moreno, António J.; Oliveira, Catarina R.; Santos, Maria S.. Autor correspondente: # Cunha-Oliveira, Teresa. "Mitochondrial complex I dysfunction induced by cocaine and cocaine plus morphine in brain and liver mitochondria". Toxicology Letters 219 3 (2013): 298-306. http://dx.doi.org/10.1016/j.toxlet.2013.03.025.
    Publicado • 10.1016/j.toxlet.2013.03.025
  43. # Cunha-Oliveira, Teresa; Rego, A. Cristina; Oliveira, Catarina R.. Autor correspondente: # Cunha-Oliveira, Teresa. "Oxidative Stress and Drugs of Abuse: An Update". Mini-Reviews in Organic Chemistry 10 4 (2013): 321-334. http://dx.doi.org/10.2174/1570193X113106660026.
    Acesso aberto • Publicado • 10.2174/1570193X113106660026
  44. Bernardo, Telma C.; Cunha-Oliveira, Teresa; Serafim, Teresa L.; Holy, Jon; Krasutsky, Dmytro; Kolomitsyna, Oksana; Krasutsky, Pavel; Moreno, António M.; Oliveira, Paulo J.. "Dimethylaminopyridine derivatives of lupane triterpenoids cause mitochondrial disruption and induce the permeability transition". Bioorganic & Medicinal Chemistry 21 23 (2013): 7239-7249. http://dx.doi.org/10.1016/j.bmc.2013.09.066.
    Acesso aberto • Publicado • 10.1016/j.bmc.2013.09.066
  45. # Cunha-Oliveira, Teresa; Silva, Lisbeth; Silva, Ana Maria; Moreno, António J.; Oliveira, Catarina R.; Santos, Maria S.. Autor correspondente: # Cunha-Oliveira, Teresa. "Acute effects of cocaine, morphine and their combination on bioenergetic function and susceptibility to oxidative stress of rat liver mitochondria". Life Sciences 92 24-26 (2013): 1157-1164. http://dx.doi.org/10.1016/j.lfs.2013.04.016.
    Acesso aberto • Publicado • 10.1016/j.lfs.2013.04.016
  46. Ribeiro, Márcio; Rosenstock, Tatiana R.; Cunha-Oliveira, Teresa; Ferreira, Ildete L.; Oliveira, Catarina R.; Rego, A. Cristina. "Glutathione redox cycle dysregulation in Huntington’s disease knock-in striatal cells". Free Radical Biology and Medicine 53 10 (2012): 1857-1867. http://dx.doi.org/10.1016/j.freeradbiomed.2012.09.004.
    Publicado • 10.1016/j.freeradbiomed.2012.09.004
  47. Pereira, Frederico C.; Cunha-Oliveira, Teresa; Viana, Sofia D.; Travassos, Ana S.; Nunes, Sara; Silva, Carlos; Prediger, Rui Daniel; et al. "Disruption of striatal glutamatergic/GABAergic homeostasis following acute methamphetamine in mice". Neurotoxicology and Teratology 34 5 (2012): 522-529. http://dx.doi.org/10.1016/j.ntt.2012.07.005.
    Publicado • 10.1016/j.ntt.2012.07.005
  48. Perfeito, R.; * Cunha-Oliveira, T.; Rego, A.C.. "Revisiting oxidative stress and mitochondrial dysfunction in the pathogenesis of Parkinson disease - Resemblance to the effect of amphetamine drugs of abuse". Free Radical Biology and Medicine 53 9 (2012): 1791-1806. http://www.scopus.com/inward/record.url?eid=2-s2.0-84867397192&partnerID=MN8TOARS.
    10.1016/j.freeradbiomed.2012.08.569
  49. Ferreira, I. Luisa; * Cunha-Oliveira, Teresa; Nascimento, Maria V.; Ribeiro, Márcio; Proença, M. Teresa; Januário, Cristina; Oliveira, Catarina R.; Rego, A. Cristina. "Bioenergetic dysfunction in Huntington's disease human cybrids". Experimental Neurology 231 1 (2011): 127-134. http://dx.doi.org/10.1016/j.expneurol.2011.05.024.
    Publicado • 10.1016/j.expneurol.2011.05.024
  50. Cunha-Oliveira, T.; Rego, A.C.; Garrido, J.; Borges, F.; Macedo, T.; Oliveira, C.R.. "Neurotoxicity of heroin-cocaine combinations in rat cortical neurons". Toxicology 276 1 (2010): 11-17. http://dx.doi.org/10.1016/j.tox.2010.06.009.
    Publicado • 10.1016/j.tox.2010.06.009
  51. Almeida, S.; Laço, M.; Cunha-Oliveira, T.; Oliveira, C.R.; Rego, A.C.. "BDNF regulates BIM expression levels in 3-nitropropionic acid-treated cortical neurons". Neurobiology of Disease 35 3 (2009): 448-456. http://dx.doi.org/10.1016/j.nbd.2009.06.006.
    Publicado • 10.1016/j.nbd.2009.06.006
  52. Almeida, Sandra; Cunha-Oliveira, Teresa; Laço, Mário; Oliveira, Catarina R.; Rego, A. Cristina. "Dysregulation of CREB Activation and Histone Acetylation in 3-Nitropropionic Acid-Treated Cortical Neurons: Prevention by BDNF and NGF". Neurotoxicity Research 17 4 (2009): 399-405. http://dx.doi.org/10.1007/s12640-009-9116-z.
    Acesso aberto • Publicado • 10.1007/s12640-009-9116-z
  53. Cunha-Oliveira, T.; Rego, A.C.; Oliveira, C.R.; Cunha-Oliveira, Teresa; Rego, Ana Cristina; Oliveira, Catarina R.. "Cellular and molecular mechanisms involved in the neurotoxicity of opioid and psychostimulant drugs". Brain Research Reviews 58 1 (2008): 192-208. http://dx.doi.org/10.1016/j.brainresrev.2008.03.002.
    10.1016/j.brainresrev.2008.03.002
  54. Cunha-Oliveira, T.; Rego, A.C.; Garrido, J.; Borges, F.; Macedo, T.; Oliveira, C.R.. "Street heroin induces mitochondrial dysfunction and apoptosis in rat cortical neurons". Journal of Neurochemistry 101 2 (2007): 543-554. http://dx.doi.org/10.1111/j.1471-4159.2006.04406.x.
    10.1111/j.1471-4159.2006.04406.x
  55. Cunha-Oliveira, T; Rego, AC; Macedo, T; Oliveira, CR. "Adaptation to oxidative stress in the chronic effects of cocaine and amphetamine". Free Radical Research 41 (2007): S22-S22. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000252296300068&KeyUID=WOS:000252296300068.
  56. Cunha-Oliveira, T.; Rego, A.C.; Cardoso, S.M.; Borges, F.; Swerdlow, R.H.; Macedo, T.; de Oliveira, C.R.. "Mitochondrial dysfunction and caspase activation in rat cortical neurons treated with cocaine or amphetamine". Brain Research 1089 1 (2006): 44-54. http://dx.doi.org/10.1016/j.brainres.2006.03.061.
    Publicado • 10.1016/j.brainres.2006.03.061
  57. Domingues, A.; * Oliveira, T.C.; Laço, M.L.N.; Macedo, T.R.A.; Oliveira, C.R.; Rego, A.C.. "Expression of NR1/NR2B N-methyl-D-aspartate receptors enhances heroin toxicity in HEK293 cells". Annals of the New York Academy of Sciences 1074 (2006): 458-465. http://dx.doi.org/10.1196/annals.1369.046.
    Publicado • 10.1196/annals.1369.046
  58. Cunha-Oliveira, Teresa; Rego, A Cristina; Morgadinho, M Teresa; Macedo, Tice R; Oliveira, Catarina R. "Efeito crónico da heroína e do peróxido de hidrogénio em células PC12". Coimbra Médica V 2 1 (2006): 21-29. http://hdl.handle.net/10316/18520.
    Acesso aberto • Publicado
  59. Cunha-Oliveira, Teresa; Rego, A. Cristina; Morgadinho, Maria Teresa; Macedo, Tice; Oliveira, Catarina Resende. "Differential cytotoxic responses of PC12 cells chronically exposed to psychostimulants or to hydrogen peroxide". Toxicology 217 1 (2006): 54-62. http://dx.doi.org/10.1016/j.tox.2005.08.022.
    Acesso aberto • 10.1016/j.tox.2005.08.022
  60. Milhazes, N.; Cunha-Oliveira, T.; Martins, P.; Garrido, J.; Oliveira, C.; Rego, A.C.; Borges, F.. "Synthesis and cytotoxic profile of 3,4-methylenedioxymethamphetamine ("ecstasy") and its metabolites on undifferentiated PC12 cells: A putative structure-toxicity relationship". Chemical Research in Toxicology 19 10 (2006): 1294-1304. http://www.scopus.com/inward/record.url?eid=2-s2.0-33750209029&partnerID=MN8TOARS.
    10.1021/tx060123i
  61. Cunha-Oliveira, T.; Rego, A.C.; Macedo, T.; Oliveira, C.R.. "Drugs of abuse induce apoptotic features in PC12 cells". Annals of the New York Academy of Sciences 1010 1 (2003): 667-670. http://dx.doi.org/10.1196/annals.1299.121.
    Publicado • 10.1196/annals.1299.121
  62. # Cunha-Oliveira, T.; Rego, A.C.; Morgadinho, M.T.; Macedo, T.R.A.; Oliveira, C.R.. Autor correspondente: # Cunha-Oliveira, T.. "Toxic effects of opioid and stimulant drugs on undifferentiated PC12 cells". Annals of the New York Academy of Sciences 965 (2002): 487-496. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036290212&partnerID=MN8TOARS.
    Publicado • 10.1111/j.1749-6632.2002.tb04190.x
Capítulo de livro
  1. Luciana L. Ferreira; Rafael Silveira; Paulo J. Oliveira; Cunha-Oliveira, T.. "Epigenetics in doxorubicin cardiotoxicity". editado por Ramón Cacabelos, 919-928. Academic Press, 2025.
    10.1016/b978-0-443-18722-3.00035-9
  2. Alexandra C. de Lemos; José Carlos Santos Teixeira; Teresa Cunha-Oliveira. "Characterization of the Mitochondria Function and Metabolism in Skin Fibroblasts Using the Biolog MitoPlate S-1". In Mitochondrial Bioenergetics. Methods in Molecular Biology, 75-98. Humana, 2024.
    Publicado • 10.1007/978-1-0716-4264-1_5
  3. Sónia A. Pinho; Georgina L. Gardner; Ricardo Alva; Jeff A. Stuart; Teresa Cunha-Oliveira. Autor correspondente: Teresa Cunha-Oliveira. "Creating Physiological Cell Environments In Vitro: Adjusting Cell Culture Media Composition and Oxygen Levels to Investigate Mitochondrial Function and Cancer Metabolism". In Mitochondrial Bioenergetics. Methods in Molecular Biology, 163-199. Humana, 2024.
    Publicado • 10.1007/978-1-0716-4264-1_9
  4. Gonçalo J.M. Afonso; Rui F. Simões; Sonia L.C. Pinho; Paulo J. Oliveira; Teresa Cunha-Oliveira. "Challenges in mitochondrial profiling during pre-clinical studies". 2023.
    10.1016/B978-0-323-88462-4.00002-X
  5. Jorge Henriques; Caio Ribeiro; Teresa Rocha; Paulo de Carvalho; Duarte, Ana I.; Freitas, Alex; Cunha-Oliveira, T.; Francisco Baptista Pereira. "Machine learning in the context of better healthcare in aging". In AGING: FROM FUNDAMENTAL BIOLOGY TO SOCIETAL IMPACT. Elsevier, 2022.
    No prelo
  6. Vega-Naredo, Ignacio; Oliveira, Gabriela; Cunha-Oliveira, Teresa; Serafim, Teresa; Sardão, Vilma A.; Oliveira, Paulo J.. "Analysis of Proapoptotic Protein Trafficking to and from Mitochondria". In Methods in Molecular Biology, 161-178. Springer US, 2021.
    Publicado • 10.1007/978-1-0716-1433-4_10
  7. # Cunha-Oliveira, T.; Rego, A. C.; Oliveira, C.R. Autor correspondente: # Cunha-Oliveira, T.. "Cocaine as a Neurotoxin". In Handbook of Neurotoxicity,, editado por Kostrzewa, R.M.. Springer, 2021.
    Publicado • 10.1007/978-3-030-71519-9_81-1
  8. Ferreira, Luciana L.; Oliveira, Paulo J.; # Cunha-Oliveira, Teresa. Autor correspondente: # Cunha-Oliveira, Teresa. "Epigenetics in Doxorubicin Cardiotoxicity". In Pharmacoepigenetics, editado por Cacabelos, Ramón, 837-846. Elsevier, 2019.
    Publicado • 10.1016/b978-0-12-813939-4.00033-4
  9. Abreu, P. L.; Ferreira, L. M. R.; Cunha-Oliveira, T.; Alpoim, M.C.; Urbano, A. M.. "HSP90: A Key Player in Metal-Induced Carcinogenesis?". In Heat Shock Protein 90 in Human Diseases and Disorders, editado por Dr. Punit Kaur. Springer International Publishing, 2019.
    Publicado • 10.1007/978-3-030-23158-3_11
  10. Simões, Rui F.; Cunha-Oliveira, Teresa; Costa, Cláudio F.; Sardão, Vilma A.; Oliveira, Paulo J.. "In Vitro Methodologies to Investigate Drug-Induced Toxicities". In Mitochondrial Dysfunction Caused by Drugs and Environmental Toxicants, 229-247. John Wiley & Sons, Inc., 2018.
    Publicado • 10.1002/9781119329725.ch14
  11. Ferreira, Luciana L.; Coelho, Ana Raquel; Oliveira, Paulo J.; # Cunha-Oliveira, Teresa. Autor correspondente: # Cunha-Oliveira, Teresa. "Mitochondrial Toxicity Induced by Chemotherapeutic Drugs". In Mitochondrial Dysfunction Caused by Drugs and Environmental Toxicants, 593-612. John Wiley & Sons, Inc., 2018.
    Publicado • 10.1002/9781119329725.ch40
  12. Pereira, S.P.; # Cunha-Oliveira, T.. Autor correspondente: # Cunha-Oliveira, T.. "Role of Mitochondria on the Neurological Effects of Cocaine". In The Neuroscience of Cocaine, 205-218. Elsevier, 2017.
    Publicado • 10.1016/b978-0-12-803750-8.00021-x
  13. # Cunha-Oliveira, T.. Autor correspondente: # Cunha-Oliveira, T.. "Alucinogénios". In Toxicologia Forense, 233-247. Lisboa, Portugal: Pactor, 2015.
    Publicado
  14. # Cunha-Oliveira, Teresa; Rego, A. Cristina; Oliveira, Catarina R. Autor correspondente: # Cunha-Oliveira, Teresa. "Cocaine as a Neurotoxin". In Handbook of Neurotoxicity, 277-297. New York, NY: Springer New York, 2014.
    Publicado • 10.1007/978-1-4614-5836-4_81
  15. Vega-Naredo, Ignacio; Cunha-Oliveira, Teresa; Serafim, Teresa L.; Sardao, Vilma A.; Oliveira, Paulo J.. "Analysis of Pro-apoptotic Protein Trafficking to and from Mitochondria". In Methods in Molecular Biology, 163-180. New York, Estados Unidos: Springer New York, 2014.
    Publicado • 10.1007/978-1-4939-1875-1_14
  16. # Cunha-Oliveira, Teresa; Rego, Ana Cristina; Carvalho, Félix; Oliveira, Catarina R.. Autor correspondente: # Cunha-Oliveira, Teresa. "Medical Toxicology of Drugs of Abuse". In Principles of Addiction, 159-175. USA: Elsevier, 2013.
    Publicado • 10.1016/B978-0-12-398336-7.00017-6
  17. # Cunha-Oliveira, T.; Rego, A.C.; Oliveira, C.R.. Autor correspondente: # Cunha-Oliveira, T.. "Neurotoxicity of cocaine". In Cocaine Abuse:Pharmacology, Treatment and Relapse Prevention, 99-113. Nova Science Publishers, Inc., 2012.
    Publicado
  18. Cunha-Oliveira, Teresa; Ferreira, Ildete L; Rego, A Cristina. "Consequences of mitochondrial dysfunction in Huntington's Disease and protection via phosphorylation pathways". In Huntington's Disease - Core Concepts and Current Advances, editado por Tunali N.E., 361-390. InTech- Open Access Publisher, 2012.
    Publicado • 10.5772/32728
Livro
  1. Cunha-Oliveira, T.. Neuronal dysfunction induced by drugs of abuse- cellular and molecular approach (ISBN 9783639176698). Alemanha: VDM- Verlag Publishing. 2009.
    Publicado
Manual
  1. Cunha-Oliveira, T.; Rego, A.C.. Mitochondrial Apoptotic Pathway- https://youtu.be/9tXwp9hli7w. 2007.
  2. Rego, A.C.; Cunha-Oliveira, T.; Almeida, L.P.. Molecular mechanisms of Huntington's disease neuropathology - https://youtu.be/V5lQWNnP71Y. 2007.
Poster em conferência
  1. Pinho, Sónia Andreia; Miranda-Santos, Inês; Costa, Cláudio F.; Pinho, Sonia L. C:; Olivia Bagshaw; Valente, Andrew; Stuart, Jeffrey; Oliveira, Paulo J. (E41F-4FB7-5948); Cunha-Oliveira, T.. "Metabolic remodeling upon up-regulation of oxidative phosphorylation in human skin fibroblasts as a tool for personalized medicine". Trabalho apresentado em Mitochondrial Medicine (Virtual Conference), 2020.
  2. Silva, Filomena S.G.; Cunha-Oliveira, T.; Silva, Daniela F.; Segura, Luis; Rosenstock, Tatiana; Oliveira, Paulo J. (E41F-4FB7-5948). "Oxidant/antioxidant imbalance in lymphoblasts from amyotrophic lateral sclerosis patients with SOD1 mutations and unknown mutations". Trabalho apresentado em Targeting Mitochondria 2020, 2020.
  3. Costa, Cláudio F.; Pinho, Sónia Andreia; Pinho, Sonia L. C:; Oliveira, Paulo J; Cunha-Oliveira, T.. "Molecular and functional characterization of human skin fibroblasts in different metabolic contexts". Trabalho apresentado em FEBS 2019 Advanced Course. Oncometabolism: From Conceptual Knowledge to Clinical Applications, Luso, Portugal, 2019.
  4. Ferrão, Rafaela; Pinho, Sonia L. C:; Simões, Rui F.; Lourenço, Nuno; Cunha-Oliveira, T.. "Early mitochondrial changes associated with the toxicity of different drugs of abuse in differentiated SH-SY5Y cells". Trabalho apresentado em FEBS 2019 Advanced Course. Oncometabolism: From Conceptual Knowledge to Clinical Applications, 2019.
  5. Pino, Rute; Cunha-Oliveira, T.; Carvalho, Filipa S.; Garcia, Rita; Burgeiro, Ana; Carvalho, Rui; Oliveira, Paulo J.; Lourenço, Nuno. "Unraveling metabolic effects underlying acute cardiotoxicity of the antineoplastic drug Doxorubicin". Trabalho apresentado em FEBS 2019 Advanced Course. Oncometabolism: From Conceptual Knowledge to Clinical Applications, Luso, Portugal, 2019.
  6. Silva, Filomena S.G.; Cunha-Oliveira, T.; Bento, Guida; Oliveira, Paulo J.. "Data mining analysis of respiratory and glycolytic fluxes from amyotrophic lateral sclerosis patients: Unraveling the effect of SOD1 mutation.". Trabalho apresentado em FEBS 2019 Advanced Course. Oncometabolism: From Conceptual Knowledge to Clinical Applications, Luso, Portugal, 2019.
  7. Simoes, R. F.; Cunha-Oliveira, T.; Oliveira, P. J.; Pereira, F. B.. "Dose-dependent analysis of mitochondrial parameters in differentiated SH-SY5Y cells exposed to mitochondrial toxicants". Trabalho apresentado em MitoPorto 2018: Mitochondrial evolution, metabolism and disease, 2018.
  8. Deus, C. M.; Pereira, S. P.; Cunha-Oliveira, T.; Benfeito, S.; Cagide, F.; Borges, F.; Raimundo, N.; Oliveira, P. J.. "Targeting mitochondria with mitochondria-targeted cinnamic antioxidants: a new avenue for sporadic Parkinson’s Disease therapy". Trabalho apresentado em MitoPorto 2018: Mitochondrial evolution, metabolism and disease, 2018.
  9. Pereira, S. P.; Cavallaro, C.H.; Grilo, L.; Martins, J.D.; Cardoso, I.; Cunha-Oliveira, T.; Baldeiras, I.; et al. "Being obese during pregnancy: the mitochondrial impact in maternal hepatic tissue". Trabalho apresentado em MitoPorto 2018: Mitochondrial evolution, metabolism and disease, 2018.
  10. Costa, C. F.; Pinho, S. L.; Sardao, V. A.; Teixeira, J.; Oliveira, P. J.; Cunha-Oliveira, T.. "Standardization and characterization of cell culture conditions for OXPHOS induction and for mitochondrial health studies in human fibroblasts". Trabalho apresentado em MitoPorto 2018: Mitochondrial evolution, metabolism and disease, 2018.
  11. Cardoso, I.; Cunha-Oliveira, T.; Pinho, S. A.; Cavallaro, C.H.; Baldeiras, I.; Pereira, S. P.; Ford, S.; Nathanielsz, P. W.; Oliveira, P. J.. "Remodelling of liver mitochondrial bioenergetics in offspring from obese mothers in a sheep model". Trabalho apresentado em MitoPorto 2018: Mitochondrial evolution, metabolism and disease, 2018.
  12. Fonseca, A.C.R.; Burgeiro, A.; Dias, C.; Baldeiras, I.; Cunha-Oliveira, T.; Lourenço, N.; Costa-Nunes, J.; et al. "Mitochondrial function and oxidative stress in epicardial versus subcutaneous adipose tissue from heart failure patients with and without diabetes". Trabalho apresentado em MitoPorto 2018: Mitochondrial evolution, metabolism and disease, 2018.
  13. Simoes, R. F.; Cunha-Oliveira, T.; Oliveira, P. J.; Pereira, F. B.. "Optimization of experimental and computational processes to study mitochondrial trafficking and metabolic biomarkers". Trabalho apresentado em 52nd Annual Meeting of the European Society for Clinical Investigation, Barcelona, Spain, 2018.
  14. Deus, C. M.; Pereira, S. P.; Cunha-Oliveira, T.; Benfeito, S.; Cagide, F.; Borges, F.; Raimundo, N.; Oliveira, P. J.. "Targeting dietary antioxidants to mitochondria ameliorate metabolic alterations of skin fibroblasts from patients with sporadic Parkinson’s Disease'". Trabalho apresentado em 52nd Annual Meeting of the European Society for Clinical Investigation, Barcelona, Spain, 2018.
  15. Pereira, S. P.; Cavallaro, C.H.; Grilo, L.; Martins, J.D.; Cardoso, I.; Baldeiras, I.; Cunha-Oliveira, T.; et al. "Mitochondrial Changes in the Maternal Liver in a Model of Obesity (MO) During Pregnancy". Trabalho apresentado em 52nd Annual Meeting of the European Society for Clinical Investigation, Barcelona, Spain, 2018.
  16. Cardoso, I.; Cunha-Oliveira, T.; Pinho, S. A.; Cavallaro, C.H.; Baldeiras, I.; Pereira, S. P.; Ford, S.; Nathanielsz, P. W.; Oliveira, P. J.. "Maternal obesity (MO) in sheep alters offspring mitochondrial hepatic biology and redefines the protein acetylation pattern". Trabalho apresentado em 52nd Meeting of the European Society for Clinical Investigation, Barcelona, Spain, 2018.
  17. Deus, C. M.; Pereira, S. P.; Cunha-Oliveira, T.; Benfeito, S.; Cagide, F.; Borges, F.; Raimundo, N.; Oliveira, P. J.. "Mitochondria-directed antioxidants increased metabolic viability of human skin fibroblasts from Parkinson’s disease patients". Trabalho apresentado em MuTaLig COST ACTION CA15135; WG meeting 2018, Tenerife, Spain, 2018.
  18. Cardoso, I.; Cunha-Oliveira, T.; Pinho, S.A.; Cavallaro, C.H.; Baldeiras, I.; Pereira, S. P.; Ford, S.; Nathanielsz, P. W.; Oliveira, P. J.. "Impacto da obesidade gestacional na função mitocondrial hepática fetal num modelo ovino". Trabalho apresentado em 14º Congresso Português de Diabetes, 2018.
  19. Fonseca, A.C.R.; Burgeiro, A.; Dias, C.; Costa-Nunes, J.; Seraphim, P.; Cunha-Oliveira, T.; Oliveira, P. J.; et al. "O tecido adiposo epicardial é bioenergeticamente mais activo do que o tecido adiposo subcutâneo". Trabalho apresentado em 14º Congresso Português de Diabetes, 2018.
  20. Grilo, L.; Pereira, S. P.; Cavallaro, C.H.; Cardoso, I.; Baldeiras, I.; Cunha-Oliveira, T.; Martins, J.D.; et al. "Alterações Mitocondriais no Fígado Materno num Modelo de Obesidade Gestacional". Trabalho apresentado em 14º Congresso Português de Diabetes, Algarve, Portugal, 2018.
  21. Cardoso, I.; Cavallaro, C.H.; Pinho, S.; Baldeiras, I.; Pereira, S. P.; Cunha-Oliveira, T.; Smith, A. M.; et al. "Maternal Obesity (MO) in Sheep Leads to Offspring (F1) Lobe-Dependent Impairment of Mitochondrial Hepatic Respiratory Chain Activity and Antioxidant Enzyme Activity". Trabalho apresentado em SRI 65th Annual Scientific Meeting, San Diego, CA, USA, 2018.
  22. Pereira, S. P.; Cavallaro, C.H.; Grilo, L.; Cardoso, I.; Baldeiras, I.; Cunha-Oliveira, T.; Smith, A. M.; et al. "Maternal Nutrient Excess and Obesity (MO) in Ewes during Pregnancy Leads to Alterations in Hepatic Mitochondrial Biology and Redox Balance". Trabalho apresentado em SRI 65th Annual Scientific Meeting, San Diego, CA, USA, 2018.
  23. Naia, L.; Cunha-Oliveira, T.; Rodrigues, J.; Rosenstock, T.; Oliveira, A.; Ribeiro, M.; Carmo, C.; et al. "Activation of pyruvate dehydrogenase complex by sodium butyrate ameliorates mitochondrial and motor phenotype in Huntington’s disease models". Trabalho apresentado em Mitoporto 2017– Advances in mitochondrial research, 2017.
  24. Serafim, T. L.; Deus, C. M.; Cunha-Oliveira, T.; Sardao, V. A.; Cunha, P.; Veloso, C.; Costa, D.; et al. "Stimulation of mitochondrial metabolism in human breast cancer cells results in increased cell motility and decreased resistance to metabolic inhibitors". Trabalho apresentado em Mitoporto 2017– Advances in mitochondrial research, 2017.
  25. Cunha-Oliveira, T.; Coelho, A. R.; Deus, C. M.; Oliveira, P. J.. "Mitochondrial dysfunction and p53 signaling in mouse stem cell-derived cardiomyocytes treated with doxorubicin". Trabalho apresentado em Mitoporto 2017– Advances in mitochondrial research, 2017.
    10.1109/ultsym.2017.8091621
  26. Serafim, T. L.; Cunha-Oliveira, T.; Deus, C. M.; Cardoso, I.; Pinho, S.A.; Yang, S.; Tuerxun, A.; et al. "Decreased Fetal Hepatic Mitochondrial Respiratory Chain Activity caused by Maternal Obesity in Sheep". Trabalho apresentado em Mitoporto 2017– Advances in mitochondrial research, 2017.
  27. Serafim, T. L.; Deus, C. M.; Pinho, S. A.; Martins, T. R.; Sardao, V. A.; Grilo, L.; Cavallaro, C.H.; et al. "Impact of Maternal Obesity During Pregnancy on Fetal Hepatic Redox Profile and Quality Control Proteins". Trabalho apresentado em Mitoporto 2017– Advances in mitochondrial research, 2017.
  28. Campos, J.; Pereira, F. B.; Costa, E.; Sardao, V. A.; Cunha-Oliveira, T.; Silva, T. B.; Simoes, R. F.; et al. "Extracting Knowledge from Data to Predict Mitochondrial Toxicity Indexes for Pharmacological Compounds". Trabalho apresentado em Mitoporto 2017– Advances in mitochondrial research, 2017.
  29. Ferreira, L. L.; Cunha-Oliveira, T.; Costa, C. F.; Oliveira, P. J.. "Protective effect of subcytotoxic doxorubicin preconditioning on H9c2 heart-derived cells viability through mitochondrial compensatory responses". Trabalho apresentado em Mitoporto 2017– Advances in mitochondrial research, 2017.
  30. Pereira, S. P.; Nijland, M. J.; Tavares, L. C.; Duarte, A. I.; Baldeiras, I.; Cunha-Oliveira, T.; Santos, M. S.; et al. "Effects of Moderate Global Maternal Nutrient Reduction on Fetal Baboon Cardiac Left Ventricular Mitochondria". Trabalho apresentado em Mitoporto 2017– Advances in mitochondrial research, 2017.
  31. Costa, C. F.; Maleita, J.; Deus, C. M.; Pereira, S. P.; Serafim, T. L.; Sardao, V. A.; Oliveira, P. J.; Cunha-Oliveira, T.. "Characterization of mitochondrial parameters in cell lines in the presence or absence of glucose". Trabalho apresentado em Mitoporto 2017– Advances in mitochondrial research, 2017.
  32. Pereira, S. P.; Tavares, L. C.; Duarte, A. I.; Cunha-Oliveira, T.; Santos, M. S.; Baldeiras, I.; Clarke, G.; et al. "Influence of Maternal Nutrition During Pregnancy on Fetal Cardiac Mitochondria Outcome". Trabalho apresentado em XIX Meeting of the Portuguese Biochemical Society, 2016.
  33. Ferreira, A. M.; Simoes, R. F.; Vilaca, A.; Carvalho, F. S.; Garcia, R.; Burgeiro, A.; Cunha-Oliveira, T.; et al. "Decreased global DNA methylation levels and gene expression patterns related metabolic end epigenetic remodeling enzymes are observed after Doxorubicin sub-chronic treatment". Trabalho apresentado em 50th Annual Meeting of the European Society for Clinical Investigation, Paris, France, 2016.
  34. Pereira, S. P.; Serafim, T. L.; Cunha-Oliveira, T.; Deus, C. M.; Starostina, I. G.; Ivanova, V. V.; Rizvanov, A. A.; Oliveira, P. J.. "Metabolic remodeling of human skin fibroblasts as model for studying mitochondrial diseases and drug-induced toxicity". Trabalho apresentado em 50th Meeting of the European Society for Clinical Investigation, Paris, France, 2016.
  35. Machado, N. G.; Cunha-Oliveira, T.; Burgeiro, A.; Oliveira, P. J.. "Influence of Exogenous Lactate on H9c2 Cardiomyoblast Gene Expression and Proliferation". Trabalho apresentado em Cancer Epigenetics and Metabolism: Connecting the Dots, 2015.
  36. Ferreira, A. M.; Vilaca, A.; Carvalho, F. S.; Garcia, R.; Burgeiro, A.; Cunha-Oliveira, T.; Oliveira, P. J.. "Doxorubicin decreases global DNA methylation levels, depletes mtDNA and causes down-regulation of transcripts for metabolic end epigenetic remodeling enzymes". Trabalho apresentado em Cancer Epigenetics and Metabolism: Connecting the Dots, 2015.
  37. Serafim, T. L.; Cunha-Oliveira, T.; Sardao, V. A.; Deus, C. M.; Greene, A.; Perkins, E.; Oliveira, P. J.. "Characterization of mitochondria of breast cancer cell lines". Trabalho apresentado em XVIII Congress of the Portuguese Biochemical Society, 2014.
  38. Martins, T. R.; Deus, C. M.; Cunha-Oliveira, T.; Oliveira, P. J.. "Berberine modulates DOX-induced cell death and autophagy in rat cardiomyoblasts". Trabalho apresentado em XVIII Congress of the Portuguese Biochemical Society, 2014.
  39. Ferreira, L. L.; Cunha-Oliveira, T.; Oliveira, P. J.. "Doxorubicin persistently alters mitochondrial gene expression in H9c2 cells". Trabalho apresentado em XVIII Congress of the Portuguese Biochemical Society, 2014.
  40. Machado, N. G.; Cunha-Oliveira, T.; Burgeiro, A.; Oliveira, P. J.. "Role of Exogenous Lactate on H9c2 Cardiomyoblast Gene Expression and Proliferation". Trabalho apresentado em XVIII Congress of the Portuguese Biochemical Society, 2014.
  41. Cunha-Oliveira, T.; Martins, T. R.; Moreira, A. C.; Branco, A. F.; Sampaio, S. F.; Holy, J.; Oliveira, P. J.; Sardao, V. A.. "Cathepsin B Activation And Apoptosis-Inducing Factor Translocation Mediate Doxorubicin-Induced Toxicity On H9c2 Cardiomyoblasts". Trabalho apresentado em XVIII Congress of the Portuguese Biochemical Society, 2014.
  42. Cunha-Oliveira, T.; Martins, T. R.; Moreira, A. C.; Branco, A. F.; Sampaio, S. F.; Holy, J.; Oliveira, P. J.; Sardao, V. A.. "Involvement of Cathepsin B and Mitochondrial Apoptosis-Inducing Factor on Doxorubicin Cardiotoxicity". Trabalho apresentado em 5th World Congress on Targeting Mitochondria, Berlin, Germany, 2014.
  43. Cunha-Oliveira, T.; Vega-Naredo, I.; Sardao, V. A.; Oliveira, P. J.. "Predicting Mitochondrial Liabilities During Drug Discovery and Development". Trabalho apresentado em Showcasing Portuguese Pharma Science: Advances in Discovery, Development and Manufacturing, 2014.
  44. Naia, L.; Ferreira, I. L.; Cunha-Oliveira, T.; Ribeiro, M.; Duarte Ana I.; Ribeiro, M.J.; Oliveira, Catarina R; et al. "Activation of IR,IGF-1R signaling pathways promote mitochondrial function and energy metabolism in Huntington’s disease human lymphoblasts". 2013.
  45. Cunha-Oliveira, T.; Silva, Lisbeth; Silva, Ana Maria; Moreno, António J; Oliveira, C.R.; Santos, Maria S.; Cunha-Oliveira, Teresa; Moreno, António J.; Oliveira, Catarina R.. "Mitochondrial complex I dysfunction induced by cocaine and cocaine plus morphine in brain and liver mitochondria". 2013.
  46. Cunha-Oliveira, T.; Naia, L.; Ferreira, I. L.; Rosenstock, T.; Duarte, A. I.; Ribeiro, M.; Laço, M.; et al. "Activation of IGF-1 and insulin signaling pathways ameliorate energy metabolism and mitochondrial function in Huntington’s disease human lymphoblasts". Trabalho apresentado em Neuroscience 2012: Annual Meeting of the Society for Neuroscience, New Orleans, LA, USA, 2012.
  47. Rosenstock, T.; Rodrigues, J.; Naia, L.; Cunha-Oliveira, T.; Rego, A. C.. "Regulation of pyruvate dehydrogenase and mitochondrial function by histone deacetylase inhibitors". Trabalho apresentado em Neuroscience 2012: Annual Meeting of the Society for Neuroscience, New Orleans, LA, USA, 2012.
  48. Cunha-Oliveira, T.; Viana, S.; Travassos, A.S.; Nunes, S.; Silva, C.; Rego, A. C.; Ali, S.F.; Fontes-Ribeiro, C.; Pereira, F. C.. "Acute methamphetamine intoxication evokes deregulation of striatal glutamatergic/gabaergic homeostasis in mice". Trabalho apresentado em 8th FENS Forum, Barcelona, Spain, 2012.
  49. Rosenstock, T.; Rodrigues, J.; Naia, L.; Cunha-Oliveira, T.; Rego, A. C.. "Impact of histone deacetylase inhibitors on pyruvate dehydrogenase and mitochondrial function in cellular models of Huntington's disease". Trabalho apresentado em 8th FENS Forum, Barcelona, Spain, 2012.
  50. Rodrigues, J.; Rosenstock, T.; Ribeiro, M.; Ferreira, I. L.; Cunha-Oliveira, T.; Rego, A.C.. "Regulation of pyruvate dehydrogenase by histone deacetylase inhibitors in Huntington’s disease striatal cells". Trabalho apresentado em 26th Meeting of the "Grupo de Estudos em Envelhecimento Cerebral e Demência", 2012.
  51. Naia, L.; Rodrigues, J.; Ribeiro, M.; Duarte, A. I.; Cunha-Oliveira, T.; Hayden, M. R.; Rego, A. C.. "Role of Insulin and IGF-1 on Glucose Metabolism in Striatal and Cortical Models of Huntington’s Disease". Trabalho apresentado em SINAL 2012 - 6th National Meeting on Cell Signaling, 2012.
  52. Rodrigues, J.; Ribeiro, M.; Cunha-Oliveira, T.; Oliveira, C.R.; Rego, A.C.. "Insulin and IGF-1 effects in energy metabolism parameters in Huntington’s disease knock-in striatal cells". 2012.
  53. Naia, L.; Ferreira, L. L.; Cunha-Oliveira, T.; Ribeiro, M.; Duarte, A. I.; Ribeiro, M. J.; Oliveira, C. R.; Rego, A. C.. "Activation of IGF-1 and insulin signaling pathways ameliorate mitochondrial function and energy metabolism in Huntington’s disease human lymphoblasts". Trabalho apresentado em Encontro da Faculdade de Medicina, 2011.
  54. Pereira, F. C.; Nunes, S.; Cunha-Oliveira, T.; Viana, S.; Silva, C.; Silva, A. M.; Travassos, A. S.; et al. "Time-Dependent Effects of Methamphetamine on Striatal Neurochemical and Astrocytic Profile and Motor Coordination in Mice". Trabalho apresentado em 3rd IDARS/ISN/ESN Satellite Meeting, 2011.
  55. Ferreira, I. L.; Cunha-Oliveira, T.; Ribeiro, M.; Nascimento, M. V.; Proença, M. T.; Januário, C.; Oliveira, C. R.; et al. "Bioenergetic dysfunction in Huntington's Disease human cybrids". Trabalho apresentado em XII Meeting of the Portuguese Neuroscience Society, 2011.
    10.1016/j.expneurol.2011.05.024
  56. Laço, M.; Ferreira, I. L.; Cunha-Oliveira, T.; Ribeiro, M.; Rosenstock, T.; Naia, L.; Ribeiro, M. J.; Oliveira, C. R.; Rego, A. C.. "IGF-1 recovers mitochondrial function in Huntington’s disease human lymphoblasts". Trabalho apresentado em SINAL 2011 5th Annual Meeting on Cell Signaling, 2011.
  57. Cunha-Oliveira, T.; Ferreira, I. L.; Nascimento, M. V.; Ribeiro, M.; Proença, T.; Januário, C.; Oliveira, C.R.; Rego, A.C.. "Impairment of energy metabolism in Huntington's Disease human cybrids". 2011.
  58. Pereira, F.C.; Viana, S.; Nunes, S.; Cunha-Oliveira, T.; Travassos, A.S.; Silva, C.; Silva, A.M.; et al. "Effect of a single high-dose of methamphetamine on striatal alpha-synuclein, RAGE, neurochemical levels and motor coordination in mice". 2011.
  59. Cunha-Oliveira, T.; Rego, A.C.; Garrido, J.; Borges, F.; Macedo, T.; Oliveira, C.R.. "Neurotoxicity of sequential and simultaneous exposure to heroin and cocaine in rat cortical neurons". 2010.
  60. Nunes, S.; Cunha-Oliveira, T.; Silva, C.; Silva, A.M.; Adrião, M.; Travassos, A.S.; Fontes-Ribeiro, C.; Reis, F.; Pereira, F.C.. "Time-dependent neurochemical and motor coordination profile of methamphetamine exposed mice". 2010.
  61. Cunha-Oliveira, T.; Rego, A.C.; Garrido, J.; Borges, F.; Macedo, T.; Oliveira, C.R.. "Neurotoxicity of cocaine-opioid combinations in rat cortical neurons". 2009.
  62. Cunha-Oliveira, T.; Marques, M.P.; Costa, R.P.; Garrido, J.; Borges, F.; Macedo, T.; Rego, A.C.; Oliveira, C.R.. "Chemistry and neurotoxicity of cocaine-opioid adducts". 2008.
  63. Cunha-Oliveira, T.; Murteira, E.; Garrido, J.; Borges, F.; Rego, A.C.; Oliveira, C.R.. "Neurotoxicity of cocaine-opioid adducts". 2008.
  64. Cunha-Oliveira, T.; Rego, A.C.; Macedo, T.; Oliveira, C.R.. "Adaptation to oxidative stress in the chronic effects of cocaine and amphetamine (P027)". 2007.
  65. Cunha-Oliveira, T.; Rego, A.C.; Macedo, T.; Oliveira, C.R.. "Changes in toxicity in PC12 cells chronically exposed to opioid and stimulant drugs of abuse and hydrogen peroxide". Trabalho apresentado em Neuroscience 2006: 36th Annual Meeting of the Society for Neuroscience, Atlanta, Georgia, USA, 2006.
  66. Cunha-Oliveira, T.; Rego, A.C.; Macedo, T.; Oliveira, C.R.. "Neurotoxicity of cocaine, amphetamine and heroin". Trabalho apresentado em Neurobiology and drug abuse - 2nd Symposium, 2006.
  67. Cunha-Oliveira, T.; Rego, A.C.; Garrido, J.; Borges, F.; Macedo, T.; Oliveira, C.R.. "Street heroin induces mitochondrial dysfunction and apoptosis in rat cortical neurons". Trabalho apresentado em IV Annual Meeting of the Center for Neuroscience and Cell Biology, 2006.
  68. Nascimento, M. V.; Ribeiro, M.; Ferreira, I. L.; Almeida, S.; Cunha-Oliveira, T.; Cardoso, S. M.; Januário, C.; et al. "Evidence for oxidative stress and increased susceptibility to apoptotic inducers in Huntington's disease cybrids and striatal cells". Trabalho apresentado em XV National Congress of Biochemistry, 2006.
  69. Cunha-Oliveira, T.; Rego, A. C.; Macedo, T.; Oliveira, C. R.. "Heroin induces mitochondrial dysfunction in rat cortical neurons". Trabalho apresentado em III Annual Meeting of the Center for Neurosciences and Cell Biology, 2005.
  70. Cunha-Oliveira, T.; Rego, A.C.; Macedo, T.; Oliveira, C.R.. "Heroin-induced degeneration of cortical neurons involves mitochondria-dependent apoptosis". Trabalho apresentado em Neuroscience 2005: 35th Annual Meeting of the Society for Neuroscience, Washington DC, USA, 2005.
  71. Cunha-Oliveira, T.; Rego, A.C.; Macedo, T.; Oliveira, C.R.. "Role of mitochondria in heroin-induced neurodegeneration". Trabalho apresentado em FEBS-IUBMB Workshop on: "Mitochondrial dynamics in cell life and death", Padova, Italy, 2005.
  72. Domingues, A.; Cunha-Oliveira, T.; Macedo, T.; Oliveira, C.R.; Rego, A.C.. "Expression of NR1/NR2B N-methyl-D-Aspartate receptors enhance heroin toxicity in HEK293 cells". Trabalho apresentado em Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Cocaine, GHB and Substituted Amphetamines, Venice, Italy, 2005.
  73. Cunha-Oliveira, T.; Rego, A.C.; Morgadinho, M.T.; Sarmento, A.; Macedo, T.; Oliveira, C.R.. "Differential cytotoxic responses of PC12 cells chronically exposed to psychostimulants or hydrogen peroxide". Trabalho apresentado em 8th Meeting of the Portuguese Neuroscience Society, 2005.
  74. Cunha-Oliveira, T.; Rego, A.C.; Macedo, T.; Oliveira, C.R.. "Involvement of oxidative stress in the neurotoxicity of drugs of abuse". Trabalho apresentado em FEBS workshop on "Free radicals and diseases: gene expression, cellular metabolism and pathophysiology", Spetses, Greece, 2004.
  75. Cunha-Oliveira, T.; Rego, A.C.; Macedo, T.; Oliveira, C.R.. "Heroin neurotoxicity is mediated by the mitochondrial apoptotic pathway". Trabalho apresentado em FEBS course on "New molecular strategies to treat neurodegenerative diseases", 2004.
  76. Cunha-Oliveira, T.; Rego, A.C.; Macedo, T.; Oliveira, C.R.. "Heroin neurotoxicity involves apoptosis and increased reactive oxygen species in rat cortical neurons". Trabalho apresentado em 4th FENS Forum, 2004.
  77. Cunha-Oliveira, T.; Rego, A.C.; Morgadinho, M.T.; Sarmento, A.; Macedo, T.; Oliveira, C.R.. "Chronic and acute effects of heroin, cocaine and amphetamine in PC12 cells". Trabalho apresentado em 1st Symposium of the International Institute of Neuroscience of Natal, Brazil, 2004.
  78. Cunha-Oliveira, T.; Rego, A.C.; Macedo, T.; Oliveira, C.R.. "Changes in Bcl-2 levels are involved in heroin-induced neuronal apoptosis". Trabalho apresentado em XIV Portuguese Biochemistry Congress, 2004.
  79. Cunha-Oliveira, T.; Rego, A.C.; Macedo, T.; Oliveira, C.R.. "Neurotoxicidade induzida pela heroína- Envolvimento da via apoptótica mitocondrial". Trabalho apresentado em IV Congresso de Investigação em Medicina, 2004.
  80. Cunha-Oliveira, T.; Rego, A.C.; Macedo, T.; Oliveira, C.R.. "Neurotoxic effects of heroin are mediated by reactive oxygen species". Trabalho apresentado em 6th Portuguese Congress on Free Radicals in Chemistry, Biology and Medicine; 1st Luso-Spanish Congress on Free Radicals, 2003.
  81. Cunha-Oliveira, T.; Rego, A.C.; Macedo, T.; Oliveira, C.R.. "Apoptotic events involved in the neurotoxicity of drugs of abuse". Trabalho apresentado em Apoptosis 2003: From signaling pathways to therapeutic tools, Luxembourg, 2003.
  82. Cunha-Oliveira, T.; Rego, A.C.; Morgadinho, M.T.; Sarmento, A.; Macedo, T.; Oliveira, C.R.. "Effect of chronic and acute administration of drugs of abuse to PC12 cells". Trabalho apresentado em 17º Encontro do Grupo de Estudos de Envelhecimento Cerebral e Demência, 2003.
  83. Cunha-Oliveira, T.; Rego, A.C.; Macedo, T.; Oliveira, C.R.. "Mitochondrial dysfunction and caspases activation in the neurotoxicity induced by heroin, amphetamine or cocaine in cortical cultures". Trabalho apresentado em 8th Meeting of the Portuguese Society of Neurosciences, 2003.
  84. Rego, A.C.; Cunha-Oliveira, T.; Macedo, T.; Oliveira, C.R.. "Involvement of mitochondrial apoptotic pathway in PC12 cell death induced by heroin, amphetamine and cocaine". Trabalho apresentado em 3rd FENS Forum of European Neuroscience, Paris, France, 2002.
  85. Cunha-Oliveira, T.; Rego, A.C.; Macedo, T.; Oliveira, C.R.. "Role of reactive oxygen species in the mechanisms of cell injury induced by cocaine, heroin and amphetamine". Trabalho apresentado em International Symposium on "Reactive oxygen and nitrogen species: diagnostic, preventive and therapeutic values", St Petersburg, Russia, 2002.
  86. Cunha-Oliveira, T.; Rego, A.C.; Macedo, T.; Oliveira, C.R.. "Apoptotic cell death induced by drugs of abuse in rat cortical neurons". Trabalho apresentado em XIII Congresso de Bioquímica, 2002.
  87. Cunha-Oliveira, T.; Rego, A.C.; Morgadinho, M.T.; Macedo, T.; Oliveira, C.R.. "Oxidative injury induced by drugs of abuse". Trabalho apresentado em III Congress on Medical Research, 2002.
  88. Cunha-Oliveira, T.; Rego, A.C.; Macedo, T.; Oliveira, C.R.. "Differential activation of caspases in the neuronal cell death induced by drugs of abuse". Trabalho apresentado em 16º Encontro do Grupo de Estudos de Envelhecimento Cerebral e Demência, 2002.
  89. Cunha-Oliveira, T.; Rego, A.C.; Macedo, T.; Oliveira, C.R.. "Drugs of abuse-induced cell death in PC12 cells". Trabalho apresentado em FEBS course on: "Mitochondrial in the cell life and death", Moscow, Russia, 2001.
  90. Cunha-Oliveira, T.; Rego, A.C.; Macedo, T.; Oliveira, C.R.. "Toxic effects of opioid and stimulant drugs on undifferentiated PC12 cells". Trabalho apresentado em Satellite Meeting of the International Society for Neurochemistry and American Society for Neurochemistry, Mar del Plata, Argentina, 2001.
  91. Cunha-Oliveira, T.; Rego, A.C.; Morgadinho, M.T.; Macedo, T.; Oliveira, C.R.. "Cell death induced by cocaine, amphetamine and heroin is associated with changes in intracellular dopamine". Trabalho apresentado em 7th Meeting of the Portuguese Neuroscience Society, 2001.
Pré-impressão
  1. Cunha-Oliveira, Teresa; Franco Silva, Daniela; Segura, Luis; Baldeiras, Inês; Marques, Ricardo; Rosenstock, Tatiana; Oliveira, Paulo J.; Silva, Filomena S.G.. "Oxidative stress profiles of lymphoblasts from Amyotrophic Lateral Sclerosis patients with or without known SOD1 mutations". 2022. https://doi.org/10.1101/2022.03.03.482309.
    10.1101/2022.03.03.482309
  2. F. Simões, Rui; J. Oliveira, Paulo; Cunha-Oliveira, Teresa; B. Pereira, Francisco. "Evaluation of 6-Hydroxydopamine and Rotenone In Vitro Neurotoxicity on Differentiated SH-SY5Y Cells Using Applied Computational Statistics". 2022. https://doi.org/10.20944/preprints202203.0093.v1.
    10.20944/preprints202203.0093.v1
  3. Simões, Rui F.; Pino, Rute; Moreira-Soares, Maurício; Kovarova, Jaromira; Neuzil, Jiri; Travasso, Rui; Oliveira, Paulo J.; Cunha-Oliveira, Teresa; Pereira, Francisco B.. "Quantitative analysis of neuronal mitochondrial movement reveals patterns resulting from neurotoxicity of rotenone and 6-hydroxydopamine". 2021. https://doi.org/10.1101/2021.02.24.432715.
    10.1101/2021.02.24.432715
  4. Costa, Cláudio F.; Pinho, Sónia A.; Pinho, Sonia L.C.; Miranda-Santos, Inês; Bagshaw, Olivia; Stuart, Jeffrey; Oliveira, Paulo J.; Cunha-Oliveira, Teresa. "Mitochondrial and metabolic remodeling in human skin fibroblasts in response to glucose availability". 2021. https://doi.org/10.1101/2021.02.24.432508.
    10.1101/2021.02.24.432508
Tese / Dissertação
  1. OLIVEIRA, MARIA. "Neuronal dysfunction induced by drugs of abuse". Doutoramento, Universidade de Coimbra Faculdade de Ciencias e Tecnologia, 2007. http://hdl.handle.net/10316/10124.
  2. Cunha-Oliveira, T.. "Neurotoxicidade induzida por drogas de abuso". Mestrado, Universidade de Coimbra Faculdade de Ciencias e Tecnologia, 2003.
  3. Cunha-Oliveira, T.. "Estudo de genética populacional em STR's". Licenciatura, Universidade de Coimbra Faculdade de Ciencias e Tecnologia, 1999.

Outros

Conjunto de dados
  1. Changes in gene expression in cells cultured in HGm or adapted to LGm or OXPHOSm - PCA.
    10.6084/M9.FIGSHARE.19102928
  2. Mitochondrial energy levels and network organization in NHDF cells cultured in HGm or adapted to OXPHOSm or to LGm..
    10.6084/M9.FIGSHARE.19102916
  3. Changes in gene expression in cells cultured in HGm or adapted to LGm or OXPHOSm.
    10.6084/M9.FIGSHARE.19102925
  4. Mitochondrial metabolism and substrate preference..
    10.6084/M9.FIGSHARE.19102922
  5. Changes in gene expression in cells cultured in HGm or adapted to LGm or OXPHOSm - Correlations..
    10.6084/M9.FIGSHARE.19103084
  6. Cunha-Oliveira, T.; Filomena Silva. Glutathione redox cycle in lymphoblasts from ALS patients and matched controls.
    10.6084/m9.figshare.19146437
  7. Cunha-Oliveira, T.; Filomena Silva. Cell lines, antibodies and primers used for oxidative stress profiling of ALS and control lymphoblasts.
    10.6084/m9.figshare.19146548
  8. Cunha-Oliveira, T.; Filomena Silva. Growth curves of ALS and control lymphoblasts.
    10.6084/m9.figshare.19146161
  9. Cunha-Oliveira, T.; Filomena Silva. SOD expression and activity in ALS lymphoblasts and matched controls.
    10.6084/m9.figshare.19146332
  10. Cunha-Oliveira, T.; Filomena Silva. Antioxidant defenses in lymphoblasts from ALS patients and matched controls..
    10.6084/m9.figshare.19146482
  11. Cunha-Oliveira, T.; Filomena Silva. Integrative analysis of oxidative stress profiles defenses of lymphoblasts from ALS patients and matched controls.
    10.6084/m9.figshare.19146491
  12. Cunha-Oliveira, T.; Filomena Silva. Oxidative stress markers and response to oxidative stimulus in lymphoblasts from ALS patients.
    10.6084/m9.figshare.19146386
  13. Cunha-Oliveira, T.; Filomena Silva. Impact of experimental group, disease, mutation, age and sex on lymphoblast metabolic profiles..
    10.6084/m9.figshare.19229268
  14. Cunha-Oliveira, T.; Filomena Silva. Pathways associated with ATP production in lymphoblasts from ALS patients with mutant SOD1 (mutSOD1) or unknown mutation (undSOD1) and respective controls..
    10.6084/m9.figshare.19229205
  15. Cunha-Oliveira, T.; Filomena Silva. Oxygen consumption rate (OCR) and extracellular acidification rate (ECAR) in lymphoblasts from ALS patients with mutant SOD1 (mutSOD1) and unknown mutation (undSOD1)..
    10.6084/m9.figshare.19229190
  16. Cunha-Oliveira, T.; Filomena Silva. Mitochondrial oxidation of TCA cycle intermediates, fatty acids, amino acids and other substrates in lymphoblasts from ALS patients with mutant SOD1 (mutSOD1) or unknown mutation (undSOD1) and respective controls..
    10.6084/m9.figshare.19229229
  17. Cunha-Oliveira, T.; Filomena Silva. Mitochondrial respiratory chain subunits, biogenesis markers and mitochondrial membrane potential in lymphoblasts from ALS patients with mutant SOD1 (mutSOD1) or unknown mutation (undSOD1) and respective controls..
    10.6084/m9.figshare.19229214
  18. Cunha-Oliveira, T.; Filomena Silva. Metadata and Summarized results.
    10.6084/m9.figshare.19229310
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2022/06/17 The importance of metabolic contexts in intracellular redox homeostasis on human dermal fibroblasts. The Future of Redox Biology, Siena, 17 a 19 June 2022
(Sienna, Itália)
2021/10/27 MITOCHONDRIAL METABOLIC PROFILES OF LYMPHOBLASTS OBTAINED FROM ALS PATIENTS WITH OR WITHOUT KNOWN SOD1 MUTATIONS 12th Congress on Targeting Mitochondria 2021
World Mitochondria Society
2021/10/13 REVERTING MITOCHONDRIAL IMPAIRMENT IN SKIN FIBROBLASTS FROM PARKINSON'S DISEASE PATIENTS BY USING A MITOCHONDRIA-TARGETED ANTIOXIDANT ANTIOXCIN4 Paris Redox 2021: 23rd International Conference on Oxidative Stress, Redox Homeostasis & Antioxidants
International Society of Antioxidants
2021/09/01 Scientific integrity and data organization “Summer with Science: Interdisciplinary Research, Development and Innovation in Pathophysiology of Diseases Dependent on Lifestyles and Aging
CNC, Center for Neuroscience and Cell Biology
2021/06/11 Oxidative Stress Profile in Lymphoblasts from Amyotrophic Lateral Sclerosis Patients with SOD1 Mutations and Unknown mutations 55th Annual Meeting of the European Society for Clinical Investigation
European Society for Clinical Investigation (ESCI)
2021/06/11 Manipulation of glucose availability promotes different in vitro redox environments in human dermal fibroblasts 55th Annual Meeting of the European Society for Clinical Investigation
European Society for Clinical Investigation (ESCI)
2021/06/11 A novel phenolic acid-based mitochondria-targeted antioxidant improves cellular responses to oxidative stress in fibroblasts from sporadic Parkinson's disease patients 55th Annual Meeting of the European Society for Clinical Investigation
European Society for Clinical Investigation (ESCI)
2021/06/11 AntiOxCIN4 a new mitochondriotropic derivative based on the natural polyphenol caffeic acid reverts cellular and mitochondrial metabolic defects of fibroblasts from idiopathic Parkinson's Disease 55th Annual Meeting of the European Society for Clinical Investigation
European Society for Clinical Investigation (ESCI)
2021/06/10 Visualization of metabolic rewiring of NHDF cells in response to extracellular glucose concentration 55th Annual Meeting of the European Society for Clinical Investigation
European Society for Clinical Investigation (ESCI)
2021/06/10 Evaluation of 6-Hydroxydopamine and Rotenone in Vitro Neurotoxicity in SH-SY5Y Cells using Computational Applied Statistics 55th Annual Meeting of the European Society for Clinical Investigation
European Society for Clinical Investigation (ESCI)
2021/06/10 Multi-dimensional Analysis of Metabolic and Mitochondrial Dysfunction Parameters in Lymphoblasts from Amyotrophic Lateral Sclerosis Patients 55th Annual Meeting of the European Society for Clinical Investigation
European Society for Clinical Investigation (ESCI)
2021/06/09 Good practices with experimental data Pre-meeting course on Bioinformatic Tools for Data Analysis
55th Annual Meeting of the European Society for Clinical Investigation
2021/01/20 (Biological) data practices and science integrity Fundamentals of Cellular and Molecular Metabolism: Relevance for Health and Disease
ITMO University (St. Petersburg, Rússia)
2020/11/17 PERSONALIZED MITOCHONDRIAL MEDICINE: COMPARING METABOLIC TOOLS TO IMPROVE HUMAN SKIN FIBROBLASTS AS MODELS Mitochondria Aging and Disease Retreat
CNC, Center for Neuroscience and Cell Biology
2020/10/29 METABOLIC RECONFIGURATION IN HUMAN SKIN FIBROBLASTS AS A TOOL FOR PERSONALIZED MITOCHONDRIAL MEDICINE 11th World Congress on Targeting Mitochondria
World Mitochondria Society
2020/10/14 Tools for Data Analysis and Machine Learning in Cell Metabolism Studies Summer Course in Interdisciplinary Research, Development and Innovation in Cellular and Molecular Metabolism
Instituto de Investigação Interdisciplinar, Universidade de Coimbra (Coimbra, Portugal)
2020/10/01 Data Analysis using Pivot Tables and Orange Summer Course in Interdisciplinary Research, Development and Innovation in Cellular and Molecular Metabolism
Instituto de Investigação Interdisciplinar, Universidade de Coimbra (Cantanhede, Portugal)
2020/09/24 Mitochondria as biosensors for disease staging and therapeutic response ESCI Virtual Meeting 2020 – COVID19 edition
European Society for Clinical Investigation (ESCI)
2020/09/24 Morphological and functional mitochondrial remodeling in human skin fibroblasts cultured with different metabolic fuels. ESCI Virtual Meeting 2020 – COVID19 edition
European Society for Clinical Investigation ESCI)
2020/09/24 Differentiated SH-SY5Y cells as a cellular model to study mitochondrial physiology and dynamics ESCI Virtual Meeting 2020 – COVID19 edition
European Society for Clinical Investigation (ESCI)
2020/09/24 Impact of Rebaudioside A in the metabolism of breast cancer cells and assessment of its chemotherapeutic potential ESCI Virtual Meeting 2020 – COVID19 edition
European Society for Clinical Investigation (ESCI)
2020/09/24 Non-supervised analysis of neurotoxicity of mitochondrial poisons 6-OHDA and rotenone ESCI Virtual Meeting 2020 – COVID19 edition
European Society for Clinical Investigation (ESCI)
2020/09/24 A Data Science Approach to Sub-chronic Doxorubicin Cardiotoxicity Reveals Hidden Patterns of Metabolic Remodeling ESCI Virtual Meeting 2020 – COVID19 edition
European Society for Clinical Investigation (ESCI)
2020/09/24 Data Extraction from Mitochondrial Motility Tracking using Computational Algorithms ESCI Virtual Meeting 2020 – COVID19 edition
European Society for Clinical Investigation (ESCI)
2020/09/24 Exploratory analysis of mitochondrial metabolism in lymphoblasts from Amyotrophic Lateral Sclerosis patients to reveals discriminant biomarkers ESCI Virtual Meeting 2020 – COVID19 edition
European Society for Clinical Investigation (ESCI)
2020/09/24 Glycolytic fluxes and metabolic profiles distinguish amyotrophic lateral sclerosis patients from healthy controls ESCI Virtual Meeting 2020 – COVID19 edition
European Society for Clinical Investigation (ESCI)
2020/05/12 Data Analysis using MS Excel. Pivot Tables and Pivot Charts. MitoXT lab meetings
CNC, Center for Neuroscience and Cell Biology (Portugal)
2020/03/12 Maternal Obesity During Pregnancy Induces Oxidative Stress and Mitochondria Functional Alterations in the Maternal Liver “Translating Reproductive Science to the Bedside” 67th Annual Meeting of the Society for Reproductive Investigation (SRI), March 10 – 14, 2020
Society for Reproductive Investigation (Vancouver, BC, Canada, Canadá)
2020/03/09 Bioinformatics and machine learning in cell biology and metabolism The Avenging Metabolism in Human Disease: Endgame!
BEB PhD Program @ CNC (Coimbra, Portugal)
2019/09/04 Unraveling metabolic effects underlying acute cardiotoxicity of the antineoplastic drug Doxorubicin FEBS 2019 Advanced Course. Oncometabolism: From Conceptual Knowledge to Clinical Applications
FEBS (Luso, Portugal)
2019/07/08 Metabolic remodeling and susceptibility to stress after forcing OXPHOS in human skin fibroblasts Mitochondrial Physiology / MitoEAGLE Training School 2019: Mitochondrial respiratory physiology: challenges on data sharing, reproducibility, and interpretation.
Mitochondrial Physiology Society (Coimbra, Portugal)
2019/07/01 Machine Learning and Uses in Mitochondrial Research Treatment School 3 on “Novel technological developments for metabolic studies”
H2020-MSCA-ITN TREATMENT GA721236 (Coimbra, Portugal)
2019/03/15 Maternal Obesity (MO) in an Ovine Model Results in Disruption of Offspring (F1) Mitochondrial Respirasomes (https://www.abstractsonline.com/pp8/#!/6816/presentation/3950) 66th Annual Scientific Meeting of the Society for Reproductive Investigation (SRI)
Society for Reproductive Investigation (SRI) (Paris, França)
2019/03/06 MitoScreening: Aplicação de Aprendizagem Automática em problemas da Biologia III MeetLab
Department of Life Sciences , FCTUC (Coimbra, Portugal)
2018/10/25 Mitochondrial DNA. Background for interpretation of mtDNA copy number and transcription data and experimental design. MitoXT lab meetings
CNC, Center for Neuroscience and Cell Biology (Cantanhede, Portugal)
2018/10/22 Mitochondrial remodeling after forcing OXPHOS in human skin fibroblasts International workshop on: Mitochondrial DNA and Derived Peptides in Health and Disease
Center for Neuroscience and Cell Biology
2018/03/11 Diabetes e doença cardíaca: uma herança da vida intrauterina? 14º Congresso Português de Diabetes
Sociedade Portuguesa de Diabetologia (Vilamoura, Portugal)
2017/11/16 Master Class on "qPCR principles and applications" MitoXT lab meetings
CNC, Center for Neuroscience and Cell Biology (Cantanhede, Portugal)
2017/07/27 Doxorubicin toxicity and mitochondrial dysfunction in mouse induced pluripotent stem cells-derived cardiomyocytes Mitochondrial Physiology Society Training School
Mitochondrial Physiology Society (Obergurgl, Áustria)
2017/05/19 Mitochondrial dysfunction and p53 signaling in mouse stem cell-derived cardiomyocytes exposed to doxorubicin 51st Annual Meeting of the European Society for Clinical Investigation
European Society for Clinical Investigation (Genoa, Itália)
2017/05/19 Altered Metabolism and Oxidative Stress in Skin Fibroblasts from Parkinson’s Disease Patients 51st Annual Meeting of the European Society for Clinical Investigation
European Society for Clinical Investigation (Genoa, Itália)
2017/05/19 Single nanomolar treatment with doxorubicin triggers mitochondrial adaptative responses in rat H9c2 cardiomyoblasts 51st Annual Meeting of the European Society for Clinical Investigation
European Society for Clinical Investigation (Genoa, Itália)
2017/05/19 Exposure of Human Bronchial Epithelial Cells to the Lung Carcinogen Hexavalent Chromium Confers Resistance to Thermal Shock and Interferes with the Stress Response 51st Annual Meeting of the European Society for Clinical Investigation
European Society for Clinical Investigation (Genoa, Itália)
2017/05/19 Remodeling of Cardiac Mitochondrial Profile in the Fetal Baboon by Moderate Global Maternal Nutrient Reduction 51st Annual Meeting of the European Society for Clinical Investigation
European Society for Clinical Investigation (Genoa, Itália)
2017/05/19 Maternal Obesity (MO) in Sheep Decreases Fetal Hepatic Mitochondrial Respiratory Chain Activity and Total Mitochondrial Lipids 51st Annual Meeting of the European Society for Clinical Investigation
European Society for Clinical Investigation (Genoa, Itália)
2016/06/23 Hexavalent Chromium, an Occupational Lung Carcinogen, Attenuates Thermal Shock Effects and Interferes with the Stress Response in Human Bronchial Epithelial Cells ICOETOX 2016
International Conference on Occupational & Environmental Toxicology (Porto, Portugal)
2016/04/29 Causes and consequences of mitochondrial dysfunction induced by drugs of abuse 50th Annual Meeting of the European Society for Clinical Investigation
European Society for Clinical Investigation (Paris, França)
2016/04/29 Maternal nutrition and fetal mitochondrial fitness 50th Meeting of the European Society for Clinical Investigation
European Society for Clinical Investigation (Paris, França)
2016/03/19 Maternal Obesity (MO) in Sheep Decreases Fetal Hepatic Mitochondrial Respiratory Chain Activity 63rd Annual Scientific Meeting of the Society for Reproductive Investigation (SRI)
Society for Reproductive Investigation (SRI) (Montreal, Canadá)
2016/01/28 Exposure of human epithelial bronchial cells to hexavalent chromium, a lung carcinogen, downregulates HSP90a and confers resistance to stress 5th CIMAGO congress
Centro de Investigação em Meio Ambiente, Genética e Oncobiologia (Coimbra, Portugal)
2015/05/30 Doxorubicin treatment induces persistent alterations in cardiomyoblast mitochondrial gene expression 49th Annual Meeting of the European Society for Clinical Investigation
European Society for Clinical Investigation (Cluj-Napoca, Roménia)
2015/02/28 Avaliação da morte celular em células cardíacas. Preparação e tratamento de células com venenos mitocondriais. (Evaluation of cell death in cardiac cells. Preparation and treatment of cells with mitochondrial poisons) Advanced course on Biomedicine: Mitochondria and Disease (2015)
Instituto de Educação e Cidadania (IEC) (Mamarrosa, Portugal)
2015/02/03 Mitochondrial characterization of human breast cancer cell lines for in vitro cancer research Cancer Epigenetics and Metabolism: Connecting the Dots
Center for Neuroscience and Cell Biology (Cantanhede, Portugal)
2015/02/03 Persistent effects in mitochondrial genes transcription after incubation of H9c2 cells with the anticancer drug Doxorubicin: an epigenetic origin? Cancer Epigenetics and Metabolism: Connecting the Dots
Center for Neuroscience and Cell Biology (Cantanhede, Portugal)
2015/01/17 Produção de energia na célula. Glicólise, Ciclo de Krebs e fosforilação oxidativa. (Cellular energy production. Glycolysis, Krebs Cycle and Oxidative Phosphorylation) Advanced course on Biomedicine: Mitochondria and Disease (2015)
Instituto de Educação e Cidadania (IEC) (Mamarrosa, Portugal)
2014/12/20 Doxorubicin Causes Down-Regulation of Transcripts for Metabolic and Epigenetic Remodeling Enzymes XVIII Congress of the Portuguese Biochemical Society
Sociedade Portuguesa de Bioquímica (Coimbra, Portugal)
2014/07/17 Deficits of pyruvate dehydrogenase and mitochondrial dysfunction in Huntington's disease - role of histone deacetylase inhibitors 18th European BioEnergetics Conference (EBEC)
(Lisbon, Portugal)
2014/06/28 Sodium butyrate protects against pyruvate dehydrogenase dysfunction in in vitro and in vivo Huntington’s disease models 28ª Reunião do Grupo de Estudo de Envelhecimento Cerebral e Demências
Grupo de Estudo de Envelhecimento Cerebral e Demências (Aveiro, Portugal)
2014/05/31 Avaliação da morte celular em células cardíacas. Preparação e tratamento de células com venenos mitocondriais. (Evaluation of cell death in cardiac cells. Preparation and treatment of cells with mitochondrial poisons) Advanced course on Biomedicine: Mitochondria and Disease (2014)
Instituto de Educação e Cidadania (IEC) (Mamarrosa, Portugal)
2014/05/03 Involvement of Mitochondrial Apoptosis-inducing Factor in Doxorubicin-induced Cardiotoxicity 48th Annual Scientific Meeting of the European Society for Clinical Investigation (ESCI)
European Society for Clinical Investigation (Utrecht, Países Baixos)
2013/11/16 Avaliação da morte celular em células cardíacas. Preparação e tratamento de células com venenos mitocondriais. (Evaluation of cell death in cardiac cells. Preparation and treatment of cells with mitochondrial poisons) Advanced course on Biomedicine: Mitochondria and Disease (2013)
Instituto de Educação e Cidadania (IEC) (Mamarrosa, Portugal)
2013/10/12 Produção de energia na célula. Glicólise, Ciclo de Krebs e Fosforilação Oxidativa. (Cellular energy production. Glycolysis, Krebs' Cycle and Oxidative Phosphorylation) Advanced course on Biomedicine: Mitochondria and Disease (2013)
Instituto de Educação e Cidadania (IEC) (Mamarrosa, Portugal)
2013 Role of histone deacetylase inhibitors on pyruvate dehydrogenase dysfunction in Huntington’s disease striatal cells 47th Annual Scientific Meeting of the European Society for Clinical Investigation (ESCI)
European Society for Clinical Investigation (ESCI) (Albufeira, Portugal, Portugal)
2012 Impacto da cocaína no cérebro II Congresso Nacional de Patologia Dual e Comportamentos Aditivos - DEPENDÊNCIA GRAVE E PATOLOGIA DUAL: MENTE DOENTE?
(Coimbra, Portugal, Portugal)
2012 Bioenergetic function and susceptibility to oxidative stress in rat liver mitochondria exposed to cocaine, morphine and their combination V Jornadas de Bioquímica
UTAD (Vila Real, Portugal)
2011 Molecular and cellular mechanisms of neurotoxicity of drugs of abuse CBTox 2011- Congresso Brasileiro de Toxicologia
Sociedade Brasileira de Toxicologia (São Paulo, Brasil)
2011 Molecular interaction between cocaine and opioids. Implications on speedball's toxicity Eurotox 2011 (47th Congress of the European Societies of Toxicology)
( Paris, France, França)
2011 Importance of Chemical and Pharmacodynamic Interactions in Speedball Abuse: The Medicinal Chemistry Outlook First III-UC Researcher Forum
Institute for Interdisciplinary Research University of Coimbra (Coimbra, Portugal)
2011 Changes in energy metabolism and cell death induced by heroin, morphine or their combinations with cocaine First III-UC Researcher Forum
Institute for Interdisciplinary Research University of Coimbra (Coimbra, Portugal)
2011 Interactions between cocaine and opioids. Implications in speedball toxicity CBTox 2011- Congresso Brasileiro de Toxicologia, Centro de Convenções de Ribeirão Preto
Sociedade Brasileira de Toxicologia (São Paulo, Brasil)
2011 Bioenergetic dysfunction in Huntington's disease human cybrids XXV Meeting of the “Grupo de Estudos do Envelhecimento Cerebral e Demência"
Grupo de Estudos do Envelhecimento Cerebral e Demência (Tomar, Portugal)
2011 Effects Of Cocaine, Morphine And Their Combination In Liver Mitochondrial Bioenergetics XLI Reunião Anual da Sociedade Portuguesa de Farmacologia, XXIX Reunião de Farmacologia Clínica e X Reunião de Toxicologia
(Coimbra, Portugal)
2011 Striatal Methamphetamine-Induced Neurotoxicity Does Not Translate Into Motor Uncoordination In Mice XLI Reunião Anual da Sociedade Portuguesa de Farmacologia, XXIX Reunião de Farmacologia Clínica e X Reunião de Toxicologia
(Coimbra, Portugal)
2011 Time-Dependent Effects of Methamphetamine on Striatal Neurochemical and Astrocytic Profile and Motor Coordination in Mice 3rd IDARS/ISN/ESN Satellite Meeting
IDARS/ISN/ESN (Istambul, Turquia)
2011 IGF-1 recovers mitochondrial function in Huntington’s disease human lymphoblasts SINAL 2011 5th Annual Meeting on Cell Signaling
(Coimbra, Portugal)
2011 Bioenergetic dysfunction in Huntington's Disease human cybrids XII Meeting of the Portuguese Neuroscience Society
Portuguese Neuroscience Society (Lisbon, Portugal)
2011 Apoptotic cell death, oxidative stress and impairment of energy metabolism in Huntington's disease human cybrids First III-UC Researcher Forum
Institute for Interdisciplinary Research (Coimbra, Portugal)
2010 Neurotoxicity of heroin, cocaine and their combinations O cérebro e a vontade: actualizações em dependências
Instituto da Droga e da Toxicodependência (Coimbra, Portugal)
2010 Heroína e cocaína. Mistura explosiva da rua para o laboratório XV Simposium do Núcleo de Estudantes de Farmácia da Universidade de Coimbra
Núcleo de Estudantes de Farmácia da Universidade de Coimbra (Coimbra, Portugal)
2010 Impacto da cocaína e do speedball no sistema nervoso central O Modelo Psicossocial: Do conceito à prática
Instituto da Droga e da Toxicodependência- Delegação Regional de Lisboa e Vale do Tejo- CRI Lisboa Ocidental- ET Restelo (Lisboa, Portugal)
2009 Toxicity of drugs of abuse Debate sobre "Drogas de abuso: drogas leves, não tão leves..."
Ciclo de conferências e debates- Introdução às ciências forenses e às neurociências (Coimbra, Portugal)
2009 Estudos laboratoriais da toxicidade e mecanismos de acção das drogas Conferência: "As drogas: da rua para o laboratório"
Instituto de Educação e Cidadania (Mamarrosa, Oliveira do Bairro, Portugal)
2008 Does heroin induce neuronal dysfunction? International Symposium on Drugs of Abuse
International Drug Abuse Research Society (Ponta Delgada, Portugal)
2008 Cellular and molecular mechanisms of cocaine and amphetamine neurotoxicity
(Portugal)
2007 Mecanismos de regulação do peso corporal e do metabolismo energético: possíveis alvos terapêuticos na toxicodependência? Olhares Cruzados sobre a Droga em Portugal
Instituto da Droga e da Toxicodependência (Sesimbra, Portugal)
2006 Neurotoxicidade da cocaína e da anfetamina Encontro da Unidade de Desabituação de Coimbra do IDT
Instituto da Droga e da Toxicodependência (Coimbra, Portugal)
2005 Apoptotic cascades involved in heroin-induced neurodegeneration 19º Encontro do Grupo de Estudos do Envelhecimento Cerebral e Demência
Grupo de Estudos do Envelhecimento Cerebral e Demência (Tomar, Portugal)
2004 Contribuição de diferentes subunidades dos receptores NMDA na citotoxicidade da heroína IV Congresso de Investigação em Medicina
Faculdade de Medicina da Universidade de Coimbra (Coimbra, Portugal)
2003 Cell injury induced by drugs of abuse Encontro do Centro de Atendimento a Toxicodependentes
Instituto da Droga e da Toxicodependência (Coimbra, Portugal)
2003 Mitochondrial dysfunction and caspases activation in the neurotoxicity induced by heroin, amphetamine or cocaine in cortical cultures International summer school on "Molecular mechanisms in homeostasis and disease"
FEBS (Federation of European Biochemical Societies) (Spetses, Grécia)
2002 Mechanisms of cell damage induced by drugs of abuse Mesas Redondas em Biomedicina
Faculdade de Medicina da Universidade de Coimbra (Coimbra, Portugal)
2002 Involvement of apoptosis in the cytotoxicity induced by drugs of abuse: cocaine, heroin and amphetamine XXXIII Congresso da Sociedade Portuguesa de Farmacologia e XXI Congresso de Farmacologia Clínica
Sociedade Portuguesa de Farmacologia (Lisboa, Portugal)

Participação em evento

Descrição da atividade
Tipo de evento
Nome do evento
Instituição / Organização
2018/09/26 - 2018/09/27 COSMETORIUM 2018 (https://www.cosmetorium.es/)
Congresso
Cosmetorium 2018
Sociedad Espanola de Quimicos Cosmeticos, Espanha
2017/09/04 - 2017/09/14 Summer School in Computational Biology (https://www.uc.pt/en/iii/initiatives/cbuc)
Oficina (workshop)
2017 Summer School in Computational Biology
Universidade de Coimbra, Portugal
2015/02/18 - 2015/03/20 ineoStart 2015: Business Acceleration and Innovation Programme (https://start.ineo.pt/)
Oficina (workshop)
ineoStart 2015
Universidade de Coimbra- Instituto Pedro Nunes, Portugal

Júri de grau académico

Tema
Tipo de participação
Nome do candidato (Tipo de grau)
Instituição / Organização
2025/07/08 Investigating Redox Heterogeneity in Human Skin Fibroblasts - From Mitochondrial Metabolism to Transcriptomics
Orientador
Sónia Andreia de Almeida Pinho (Doutoramento)
Instituto de Investigação Interdisciplinar, Universidade de Coimbra, Portugal
2021/07/21 Avaliação do potencial citotóxico e citoprotetor do óleo essencial de Tomilho Bela-luz (Thymus mastichina) em células HepG2
Orientador
Rafael Alexandre Ferreira (Outro)
Instituto Politécnico de Coimbra Escola Superior Agrária de Coimbra, Portugal
2021/07/20 Neuronal mitochondrial metabolism and dynamic profiling under physiological and pathological conditions using biological- based machine learning approaches
Orientador
Rui Fernando Vieira Lisboa Matias Simões (Doutoramento)
Universidade de Coimbra Instituto de Investigacao Interdisciplinar, Portugal
2021/06/07 Neurotoxicity of synthetic cathinones
Arguente principal
Jorge Emanuel Miranda Teixeira Soares (Doutoramento)
Universidade do Porto Faculdade de Medicina, Portugal
2020/12/16 Modulation of the Proteostasis Network and Energy Metabolism in Huntington’s Disease
Arguente principal
Tânia Raquel Pereira Soares (Doutoramento)
Universidade do Porto Faculdade de Farmácia, Portugal
2020/12/09 Impact of Rebaudioside A in cancer cell metabolism: Potential as a safe chemotherapeutic adjuvant
Orientador
Gonçalo José Martins Afonso (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2020/12/03 Effects of Extended Passaging on the BEAS-2B Cell Line, an In Vitro Model of Human Lung Epithelium Established for the Study of Lung Carcinogenesis
Orientador
Margarida Conceição Moreira Sobral (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2020/07/27 Mitochondrial pyruvate carrier inhibition as a potential approach to mitigate neurodegeneration: insights for Huntington's disease - Seminário de Doutoramento
Arguente principal
Ângela Daniela Abreu Oliveira (Doutoramento)
Universidade do Porto Faculdade de Farmácia, Portugal
2020/07/24 Evaluation of cytotoxic and cytoprotective potential of Helichrysum italicum essential oil in HepG2 cells (Avaliação do potencial citotóxico e citoprotetor do óleo essencial de Helichrysum italicum em células HepG2)
Orientador
Susana Raquel Tiago Nogueira (Outro)
Instituto Politécnico de Coimbra Escola Superior Agrária de Coimbra, Portugal
2019/12/10 Alterations in mitochondrial biogenesis and regulation of morphology in lymphoblasts from Amyotrophic Lateral Sclerosis patients
Arguente principal
Marcelo Filipe Brito Carvalho (Outro)
Instituto Politécnico de Coimbra Escola Superior Agrária de Coimbra, Portugal
2019/09/16 Mitochondria-based screening of drug neurotoxicity in differentiated SH-SY5Y cells
Orientador
Rafaela Margarida Cura Ferrão (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2018/12/04 Bioenergetics failure in human drug addiction
Arguente principal
Vanessa Filipa Rodrigues Costa (Outro)
Instituto Politécnico de Coimbra Escola Superior Agrária de Coimbra, Portugal
2018/09/21 Experimental enhancement of cellular OXPHOS reliance for mitochondrial health assessments - Development and characterization of a rapid and efficient method to induce OXPHOS in skin fibroblasts, for the assessment of mitochondrial toxicity and protection.
Orientador
Cláudio Figueiredo Costa (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2012 Pyruvate dehydrogenase and mitochondrial function in Huntington's disease models - influence of histone deacetylase inhibitors (http://hdl.handle.net/10316/26028)
Orientador
Joana Cristina Pedro Rodrigues (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2011/09/29 Efeitos da cocaína, morfina e sua combinação na bioenergética mitocondrial do fígado (http://hdl.handle.net/20.500.11816/116)
Orientador
Lisbeth Elena Sousa e Silva (Mestrado)
Cooperativa de Ensino Superior Politecnico e Universitario, Portugal
2011 Methamphetamine induces microglial cell death: protective effect of Interleukin-6 Vanessa Filipa Coelho Santos (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2010 Efeitos do peptídeo beta-amilóide no hipotálamo. Protecção por hormonas metabólicas.
Arguente principal
Sílvia Catarina Fernandes Gomes (Mestrado)
Universidade de Coimbra, Portugal
2008 Biochemical study of cocaine opioid interactions Rui Pedro Marques da Costa (Outro)
Universidade de Coimbra, Portugal

Entrevista / Programa (rádio / tv)

Programa Tema
2014/11/10 - 2014/11/10 SIC Telejornal Efeitos das drogas no cérebro
Distinções

Prémio

2020 Best communication at the Bioinformatics Symposium
ESCI- European Society for Clinical Investigation, Países Baixos
2003 Best poster at FEBS course (Greece)
Federação das Sociedades Europeias de Bioquímica (FEBS), Portugal
2002 Best poster at St Petersburg (Russia)
International Symposium on "Reactive oxygen and nitrogen species: diagnostic, preventive and therapeutic values", Rússia

Outra distinção

2008 Brain Awareness Week Funding
Federation of European Neuroscience Societies, Bélgica
2005 Travel fellowship- YTF
Federação das Sociedades Europeias de Bioquímica (FEBS), Portugal
2005 Travel fellowship FLAD
Fundação Luso-Americana, Portugal
2005 Travel fellowship- Gulbenkian Foundation
Fundação Calouste Gulbenkian, Portugal
2004 Travel fellowship- NATO
NATO, Bélgica
2004 Travel fellowship- SPN
Sociedade Portuguesa de Neurociências, Portugal
2003 Travel fellowship- YTF
Federação das Sociedades Europeias de Bioquímica (FEBS), Portugal
2002 Travel fellowship- SPB
Sociedade Portuguesa de Bioquímica, Portugal
2001 Travel fellowship- YTF
Federação das Sociedades Europeias de Bioquímica (FEBS), Portugal