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Lino Ferreira is Investigator Coordinator (equivalent to Full Professor) at the Faculty of Medicine at the University of Coimbra and affiliated with the Center of Neurosciences and Cell Biology (CNC) a research unit at the same University. In the last 5 years, the lab has contributed for two main avenues of research: (i) disease modeling and drug screening program based on (aged) tissue models from human stem cells and (ii) therapies based on nanomedicine platforms. The lab has done significant contributions at the interface of engineering with biology, in particular, in the development of advanced nanoformulations for medical applications (https://doi.org/10.1002/anie.201911398; https://doi.org/10.1021/acsnano.7b07538; https://doi.org/10.1038/ncomms15204), tissue models for screening and disease modeling (https://doi.org/10.1073/pnas.1617451114; https://doi.org/10.1038/s41467-017-00746-7), particularly in the area of ageing (https://doi.org/10.1038/s41467-020-17901-2) and in the use of extracellular vesicles as delivery systems (https://doi.org/10.1002/jev2.12111; https://doi.org/10.1021/acsnano.9b00376). In the last 5 years, he attracted 7.45 million euros of competitive funding including 1 ERA Chair project, 1 Twinning project, 1 Marie Curie ITN project, 5 Marie Curie International fellowships as well as several FCT and industry projects. In the last 5 years, he has published 63 articles in international peer-reviewed journals and 4 book chapters and he has disseminated his work in more than 50 international conferences. Since the beginning of his career he gathered more than 10200 citations by peers, endowing him an h-index of 52. Members of his group have founded companies (e.g. Tissium, Exogenus Therapeutics, Matera, Curemat) that attracted more than 50M € in venture capital. He is the inventor of more than 20 international patents (10 licensed to companies). He has successfully supervised 20 PhD students (11 in the last 5 years) and 15 post-docs (5 in the last 5 years). Four of the previous members are now independent Principal Investigators; two members have launched companies; 10 members have started positions in industry; the remaining are in research. He was the recipient of innumerous awards/prizes including Bluepharma innovation (2016), FCT Investigation (2013 and 2015) and the Crioestaminal prizes (2008). He was President of the Portuguese Society of Stem cells and Cell Therapies (2013-2015). He is the associate editor of the journal Biomaterials Science (since 2019). He is the coordinator of the collaborative laboratory called Colab4Ageing (since 2021) that joins several stakeholders in the chain value, to develop, test and implement innovative products and services in the area of ageing. He is member of the Scientific Counsel of 3Is and Faculty of Medicine and Member of the board of the Center of Neurosciences and Cell Biology, University of Coimbra.
Identificação

Identificação pessoal

Nome completo
Lino Ferreira

Nomes de citação

  • Ferreira, Lino

Identificadores de autor

Ciência ID
7213-B63A-ECA6
ORCID iD
0000-0001-8985-9302
Google Scholar ID
https://scholar.google.com/citations?user=WNUIcigAAAAJ&hl=pt-PT

Telefones

Telemóvel
  • 963379228 (Pessoal)

Moradas

  • Faculty of Medicine Pólo das Ciências da Saúde, Unidade Central Azinhaga de Santa Comba, 3000-354, Coimbra, Coimbra, Portugal (Profissional)

Websites

  • http://erachair.uc-biotech.pt (Académico)

Domínios de atuação

  • Ciências da Engenharia e Tecnologias - Engenharia Médica - Engenharia Médica
  • Ciências da Engenharia e Tecnologias - Nanotecnologia
  • Ciências Médicas e da Saúde - Biotecnologia Médica - Biomateriais
  • Ciências Médicas e da Saúde - Biotecnologia Médica - Tecnologias que envolvem a Manipulação de Células,Tecidos,Órgãos ou todo o Organismo
  • Ciências Médicas e da Saúde - Biotecnologia Médica - Diagnóstico e Terapias de Base Genética

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Francês Utilizador independente (B2) Utilizador independente (B2) Utilizador independente (B2) Utilizador independente (B2) Utilizador independente (B2)
Formação
Grau Classificação
1999/09/01 - 2003/11/24
Concluído
PhD in Chemical Engineering (Doutoramento)
Especialização em Biotecnologia- PhD degree performed in a sandwich program between Rensselaer Polytechnic Institute (New York, USA) and University of Coimbra (Portugal)
Universidade de Coimbra, Portugal
Distinção e Louvor
1995/09/01 - 1998/03/06
Concluído
MSc in Biochemistry (Mestrado)
Universidade de Coimbra Departamento de Ciências da Terra, Portugal
"Enzymatic modification of sacharides" (TESE/DISSERTAÇÃO)
Very Good
1989/09/01 - 1994/07/20
Concluído
BSc in Biochemistry (Licenciatura)
Universidade de Coimbra Departamento de Ciências da Vida, Portugal
Good
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento
Empregador
2021/05/01 - Atual Investigador Coordenador (carreira) (Investigação) Universidade de Coimbra, Portugal
Universidade de Coimbra Faculdade de Medicina, Portugal
2016/11/01 - Atual Investigador Coordenador Convidado (carreira) (Investigação) Universidade de Coimbra Faculdade de Medicina, Portugal
Universidade de Coimbra Faculdade de Medicina, Portugal
2015/05/01 - 2016/11/01 Investigador Coordenador (carreira) (Investigação) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2013/01/01 - 2015/05/01 Investigador principal (carreira) (Investigação) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2007/09/01 - 2012/12/31 Investigador Auxiliar (carreira) (Investigação) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2004/09/01 - 2007/08/31 Pós-doutorado (Investigação) Massachusetts Institute of Technology, Estados Unidos
2003/09/01 - 2004/08/31 Pós-doutorado (Investigação) Instituto Nacional de Engenharia Biomédica, Portugal

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento
Empregador
2001/09/01 - 2002/03/31 Assistente convidado (Docente Ensino Superior Politécnico) Instituto Politécnico de Coimbra Escola Superior Agrária de Coimbra, Portugal

Cargos e Funções

Categoria Profissional
Instituição de acolhimento
Empregador
2022/01/19 - Atual Colab4Ageing- Member of Installation Committee Universidade de Coimbra, Portugal
2019/06/01 - Atual Member of Centro de Neurociências e Biologia Celular Board Universidade de Coimbra, Portugal
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2010/12/01 - 2010/12/31 Invited Professor Université d'Artois Bibliothèque de Lens, França

Outros

Categoria Profissional
Instituição de acolhimento
Empregador
2020/09/01 - Atual Member of the Scientific Counsel of 3Is Universidade de Coimbra, Portugal
2019/05/01 - Atual Member of the Scientific Counsel of Medicine Faculty Universidade de Coimbra, Portugal
Universidade de Coimbra Faculdade de Medicina, Portugal
2018/02/01 - Atual Coordinator of one of the three thematic strands (entitled “Innovation Therapies”) of the research center CIBB Universidade de Coimbra, Portugal
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2009/01/01 - Atual Founder of Matera, a biomaterial-based company Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2008/01/01 - Atual Head of the laboratory “Biomaterials and Stem Cell-Based Therapies” at CNC Universidade de Coimbra, Portugal
2007/09/01 - Atual CNC coordinator of MIT-Portugal Program, focus in bioengineering Universidade de Coimbra, Portugal
2015/01/01 - 2018/01/01 Coordinator of the group Therapy 2 –Stem cell biotechnology, Strategic project of the consortium CNC.IBILI (Ref: UID/NEU/04539/2013), funded by Fundação para a Ciência e a Tecnologia Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2013/06/01 - 2015/10/01 President of the Portuguese Society of Stem Cells and Cell Therapies Universidade de Coimbra, Portugal
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2009/01/01 - 2010/12/31 Member of the Board of Directors of the Portuguese Society of Stem Cells and Cell Therapies Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2007/01/01 - 2008/12/31 Member of the General Assembly of the Portuguese Society of Stem Cells and Cell Therapies Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
1999/01/01 - 2003/08/31 PhD fellow at Chemical Engineering department, University of Coimbra Fundação para a Ciência e a Tecnologia, Portugal
1995/09/01 - 1997/08/31 Msc fellow at Biochemistry department of University of Coimbra Fundação para a Ciência e a Tecnologia, Portugal
Produções

Publicações

Artigo em conferência
  1. Paulo, C.; Vidal, M.; Ferreira, L.. "Antifungal nanoparticles and surfaces". 2011.
  2. Pedroso, D.C.S.; Tellechea, A.; Moura, L.; Fidalgo-Carvalho, I.; Duarte, J.; Carvalho, E.; Ferreira, L.. "Improved survival, vascular differentiation and wound healing potential of stem cells co-cultured with endothelial cells in a fibrin gel". 2011.
  3. Ferreira, L.; Squier, T.; Park, H.; Choe, H.; Kohane, D.S.; Langer, R.. "Human embryoid bodies containing particulate delivery vehicles". 2008.
  4. Zumbuehl, A.; Ferreira, L.; Kuhn, D.; Astashkina, A.; Long, L.; Yeo, Y.; Iaconis, T.; et al. "Antifungal hydrogels". 2008.
Artigo em revista
  1. Catarina Rebelo; Tiago Reis; Joana Guedes; Cláudia Saraiva; Artur Filipe Rodrigues; Susana Simões; Liliana Bernardino; et al. "Efficient spatially targeted gene editing using a near-infrared activatable protein-conjugated nanoparticle for brain applications". Nature Communications (2022): https://doi.org/10.1038/s41467-022-31791-6.
    10.1038/s41467-022-31791-6
  2. "A NIR-II emissive polymer AIEgen for imaging-guided photothermal elimination of bacterial infection". Biomaterials 286 (2022): 121579-121579. http://dx.doi.org/10.1016/j.biomaterials.2022.121579.
    10.1016/j.biomaterials.2022.121579
  3. Akhilesh Rai; Rafaela Ferrão; Denise Marta; Andreia Vilaça; Miguel Lino; Tiago Rondão; Jian Ji; Artur Paiva; Lino Ferreira. "Antimicrobial Peptide-Tether Dressing Able to Enhance Wound Healing by Tissue Contact". ACS Applied Materials & Interfaces (2022): https://doi.org/10.1021/acsami.2c06601.
    10.1021/acsami.2c06601
  4. "MicroRNA-124-3p-enriched small extracellular vesicles as a therapeutic approach for Parkinson’s disease". Molecular Therapy (2022): http://dx.doi.org/10.1016/j.ymthe.2022.06.003.
    10.1016/j.ymthe.2022.06.003
  5. "Extracellular vesicles enriched with an endothelial cell pro-survival microRNA affects skin tissue regeneration". Molecular Therapy - Nucleic Acids 28 (2022): 307-327. http://dx.doi.org/10.1016/j.omtn.2022.03.018.
    10.1016/j.omtn.2022.03.018
  6. "Intercellular transfer of miR-200c-3p impairs the angiogenic capacity of cardiac endothelial cells". Molecular Therapy 30 6 (2022): 2257-2273. http://dx.doi.org/10.1016/j.ymthe.2022.03.002.
    10.1016/j.ymthe.2022.03.002
  7. "Multi-parametric surface plasmon resonance-based intake quantification of label-free light-activated nanoparticles by therapeutic limbal stem cells for corneal blindness". Nano Select (2022): http://dx.doi.org/10.1002/nano.202200027.
    10.1002/nano.202200027
  8. Akhilesh Rai; Rafaela Ferrão; Paulo Palma; Tatiana Patricio; Paula Parreira; Elsa Anes; Chiara Tonda-Turo; et al. "Antimicrobial peptide-based materials: opportunities and challenges". Journal of Materials Chemistry B (2022): https://doi.org/10.1039/D1TB02617H.
    10.1039/D1TB02617H
  9. Tenreiro, Miguel F.; Almeida, Henrique V.; Calmeiro, Tomás; Fortunato, Elvira; Ferreira, Lino; Alves, Paula M.; Serra, Margarida. "Interindividual heterogeneity affects the outcome of human cardiac tissue decellularization". Scientific Reports 11 1 (2021): http://dx.doi.org/10.1038/s41598-021-00226-5.
    10.1038/s41598-021-00226-5
  10. Lino, Miguel M.; Simões, Susana; Tomatis, Francesca; Albino, Inês; Barrera, Angela; Vivien, Denis; Sobrino, Tomas; Ferreira, Lino. "Engineered extracellular vesicles as brain therapeutics". Journal of Controlled Release 338 (2021): 472-485. http://dx.doi.org/10.1016/j.jconrel.2021.08.037.
    10.1016/j.jconrel.2021.08.037
  11. Pires, Cristiana L.; Praça, Catarina; Martins, Patrícia A. T.; Batista de Carvalho, Ana L. M.; Ferreira, Lino; Marques, Maria Paula M.; Moreno, Maria João. "Re-Use of Caco-2 Monolayers in Permeability Assays—Validation Regarding Cell Monolayer Integrity". Pharmaceutics 13 10 (2021): 1563. http://dx.doi.org/10.3390/pharmaceutics13101563.
    10.3390/pharmaceutics13101563
  12. Inês Tomé; Vitor Francisco; Hugo Fernandes; Lino Ferreira. "High-throughput screening of nanoparticles in drug delivery". APL Bioengineering (2021): https://doi.org/10.1063/5.0057204.
    10.1063/5.0057204
  13. Abreu, Ricardo C.; Ramos, Cristiana V.; Becher, Clarissa; Lino, Miguel; Jesus, Carlos; Costa Martins, Paula A.; Martins, Patrícia A. T.; et al. "Exogenous loading of miRNAs into small extracellular vesicles". Journal of Extracellular Vesicles 10 10 (2021): http://dx.doi.org/10.1002/jev2.12111.
    10.1002/jev2.12111
  14. Bernardo-Castro, Sara; Albino, Inês; Barrera-Sandoval, Ángela María; Tomatis, Francesca; Sousa, João André; Martins, Emanuel; Simões, Susana; et al. "Therapeutic Nanoparticles for the Different Phases of Ischemic Stroke". Life 11 6 (2021): 482. http://dx.doi.org/10.3390/life11060482.
    10.3390/life11060482
  15. Rui F. Simões; Rafaela Ferrão; Margarida R. Silva; Sonia L.C. Pinho; Lino Ferreira; Paulo J. Oliveira; Teresa Cunha-Oliveira. "Refinement of a differentiation protocol using neuroblastoma SH-SY5Y cells for use in neurotoxicology research". Food and Chemical Toxicology 149 (2021): 111967-111967. https://doi.org/10.1016/j.fct.2021.111967.
    10.1016/j.fct.2021.111967
  16. Rai, Akhilesh; Ferreira, Lino. "Biomedical applications of the peptide decorated gold nanoparticles". Critical Reviews in Biotechnology 41 2 (2021): 186-215. http://dx.doi.org/10.1080/07388551.2020.1853031.
    10.1080/07388551.2020.1853031
  17. Almeida, Henrique V.; Tenreiro, Miguel F.; Louro, Ana F.; Abecasis, Bernardo; Santinha, Deolinda; Calmeiro, Tomás; Fortunato, Elvira; et al. "Human Extracellular-Matrix Functionalization of 3D hiPSC-Based Cardiac Tissues Improves Cardiomyocyte Maturation". ACS Applied Bio Materials 4 2 (2021): 1888-1899. http://dx.doi.org/10.1021/acsabm.0c01490.
    10.1021/acsabm.0c01490
  18. João Conniot; Sepehr Talebian; Susana Simões; Lino Ferreira; João Conde. "Revisiting gene delivery to the brain: silencing and editing". Biomaterials Science 9 4 (2021): 1065-1087. https://doi.org/10.1039/D0BM01278E.
    10.1039/D0BM01278E
  19. Estronca, Luís; Francisco, Vitor; Pitrez, Patrícia; Honório, Inês; Carvalho, Lara; Vazão, Helena; Blersch, Josephine; et al. "Induced pluripotent stem cell-derived vascular networks to screen nano–bio interactions". Nanoscale Horizons (2021): http://dx.doi.org/10.1039/d0nh00550a.
    Publicado • 10.1039/d0nh00550a
  20. Michela Comune; Akhilesh Rai; Paulo Palma; Chiara TondaTuro; Lino Ferreira. "Antimicrobial and pro-angiogenic properties of soluble and nanoparticle-immobilized LL37 peptides". Biomaterials Science (2021): https://doi.org/10.1039/D1BM01034D.
    10.1039/D1BM01034D
  21. Bernardo-Castro, Sara; Sousa, João André; Brás, Ana; Cecília, Carla; Rodrigues, Bruno; Almendra, Luciano; Machado, Cristina; et al. "Pathophysiology of Blood–Brain Barrier Permeability Throughout the Different Stages of Ischemic Stroke and Its Implication on Hemorrhagic Transformation and Recovery". Frontiers in Neurology 11 (2020): http://dx.doi.org/10.3389/fneur.2020.594672.
    10.3389/fneur.2020.594672
  22. Raquel Ferreira; Joseph Napoli; Tariq Enver; Liliana Bernardino; Lino Ferreira. "Advances and challenges in retinoid delivery systems in regenerative and therapeutic medicine". Nature Communications (2020): https://doi.org/10.1038/s41467-020-18042-2.
    10.1038/s41467-020-18042-2
  23. Francisco, Vitor; Rebelo, Catarina; Rodrigues, Artur Filipe; Blersch, Josephine; Fernandes, Hugo; Ferreira, Lino. "A high-throughput screening platform to identify nanocarriers for efficient delivery of RNA-based therapies". Methods (2020): http://dx.doi.org/10.1016/j.ymeth.2020.12.002.
    10.1016/j.ymeth.2020.12.002
  24. Ferreira, Lino. "Permeability of the blood brain barrier through the phases of ischemic stroke and relation with clinical outcome: protocol for a systematic review". BMJ Open 10 9 (2020): e039280.
    Publicado
  25. Pitrez PR; Estronca L; Monteiro LM; Colell G; Vazão H; Santinha D; Harhouri K; et al. "Vulnerability of progeroid smooth muscle cells to biomechanical forces is mediated by MMP13.". Nature communications (2020): http://europepmc.org/abstract/med/32807790.
    10.1038/s41467-020-17901-2
  26. Buczak K; Kirkpatrick JM; Truckenmueller F; Santinha D; Ferreira L; Roessler S; Singer S; Beck M; Ori A. "Spatially resolved analysis of FFPE tissue proteomes by quantitative mass spectrometry.". Nature protocols (2020): http://europepmc.org/abstract/med/32737464.
    10.1038/s41596-020-0356-y
  27. de Abreu RC; Fernandes H; da Costa Martins PA; Sahoo S; Emanueli C; Ferreira L. "Native and bioengineered extracellular vesicles for cardiovascular therapeutics.". Nature reviews. Cardiology (2020): http://europepmc.org/abstract/med/32483304.
    10.1038/s41569-020-0389-5
  28. Blersch, Josephine; Francisco, Vitor; Rebelo, Catarina; Jiménez-Balsa, Adrian; Antunes, Helena; Gonzato, Carlo; Pinto, Sandra; et al. "A Light-Triggerable Nanoparticle Library for the Controlled Release of Non-Coding RNAs". Angewandte Chemie International Edition 59 5 (2020): 1985-1991. http://dx.doi.org/10.1002/anie.201911398.
    10.1002/anie.201911398
  29. Josephine Blersch; Vitor Francisco; Catarina Rebelo; Adrian Jiménez-Balsa; Helena Antunes; Sandra Pinto; Susana Simões; Akhilesh Rai; Lino Ferreira. "A light-triggerable formulation to control the stability of pro-angiogenic transcription factor hypoxia inducible factor-1a (HIF-1a)". Nanoscale (2020): https://doi.org/10.1039/C9NR10503D.
    10.1039/C9NR10503D
  30. Ferreira, Lino. "A near infrared light-triggerable modular formulation for the delivery of small biomolecules". Journal of Nanobiotechnology (2019): http://dx.doi.org/10.1186/s12951-019-0530-y.
    10.1186/s12951-019-0530-y
  31. Ferreira, Lino. "Functional characterization of iPSC-derived arterial- and venous-like endothelial cells". Scientific Reports (2019): http://dx.doi.org/10.1038/s41598-019-40417-9.
    10.1038/s41598-019-40417-9
  32. Ferreira, Lino. "A light-triggerable nanoparticle library for the controlled release of non-coding RNAs.". Angewandte Chemie (International ed. in English) (2019): https://doi.org/10.1002/anie.201911398.
    10.1002/anie.201911398
  33. Ferreira, Lino. "Derivation of Brain Capillary-like Endothelial Cells from Human Pluripotent Stem Cell-Derived Endothelial Progenitor Cells.". Stem cell reports (2019): https://europepmc.org/articles/PMC6829749.
    10.1016/j.stemcr.2019.08.002
  34. Ferreira, Lino. "Spatially Confining Surface Roughness on Exponentially Growing Polyelectrolyte Multilayer Films". Advanced Materials Interfaces (2019): http://dx.doi.org/10.1002/admi.201900702.
    10.1002/admi.201900702
  35. Ferreira, Lino. "A High-Throughput Screening Method to Identify Compounds Displaying Human Vascular Embryonic Toxicity". Current Protocols in Stem Cell Biology (2019): http://dx.doi.org/10.1002/cpsc.93.
    10.1002/cpsc.93
  36. Ferreira, Lino. "The Kinetics of Small Extracellular Vesicle Delivery Impacts Skin Tissue Regeneration". ACS Nano (2019): http://dx.doi.org/10.1021/acsnano.9b00376.
    10.1021/acsnano.9b00376
  37. Ferreira, Lino. "What human blood-brain barrier models can tell us about BBB function and drug discovery?". Expert opinion on drug discovery (2019): https://doi.org/10.1080/17460441.2019.1646722.
    10.1080/17460441.2019.1646722
  38. Bernardo Abecasis; Patrícia Gomes-Alves; Susana Rosa; Pedro J. Gouveia; Lino Ferreira; Margarida Serra; Paula M. Alves. "Unveiling the molecular crosstalk in a human induced pluripotent stem cell-derived cardiac model". Biotechnology and Bioengineering 116 5 (2019): 1245-1252. https://doi.org/10.1002/bit.26929.
    10.1002/bit.26929
  39. Ferreira, Lino. "Bioprocess decision support tool for scalable manufacture of extracellular vesicles". Biotechnology and Bioengineering (2019): http://dx.doi.org/10.1002/bit.26809.
    10.1002/bit.26809
  40. Tian-tian Yao; Jing Wang; Yun-fan Xue; Wei-jiang Yu; Qiang Gao; Lino Ferreira; Ke-Feng Ren; Jian Ji. "A photodynamic antibacterial spray-coating based on the host–guest immobilization of the photosensitizer methylene blue". Journal of Materials Chemistry B (2019): https://doi.org/10.1039/C9TB01069F.
    10.1039/C9TB01069F
  41. Arnab Banerjee; Vitor Alves; Tiago Rondão; José Sereno; Ângela Neves; Miguel Lino; Andreia Ribeiro; Antero J. Abrunhosa; Lino S. Ferreira. "A positron-emission tomography (PET)/magnetic resonance imaging (MRI) platform to track in vivo small extracellular vesicles". Nanoscale 11 28 (2019): 13243-13248. https://doi.org/10.1039/C9NR02512J.
    10.1039/C9NR02512J
  42. Ferreira, Lino. "Cecropin-Melittin Functionalized Polyurethane Surfaces Prevent Staphylococcus epidermidis Adhesion without Inducing Platelet Adhesion and Activation". Advanced Materials Interfaces (2018): http://dx.doi.org/10.1002/admi.201801390.
    10.1002/admi.201801390
  43. Ferreira, Lino. "Osmotic modulation of chromatin impacts on efficiency and kinetics of cell fate modulation". Scientific Reports (2018): http://dx.doi.org/10.1038/s41598-018-25517-2.
    10.1038/s41598-018-25517-2
  44. Ferreira, Lino. "Cooperative Transcription Factor Induction Mediates Hemogenic Reprogramming". Cell Reports (2018): http://dx.doi.org/10.1016/j.celrep.2018.11.032.
    10.1016/j.celrep.2018.11.032
  45. André F. Ferreira; Michela Comune; Akhilesh Rai; Lino Ferreira; Pedro N. Simões. "Atomistic-Level Investigation of a LL37-Conjugated Gold Nanoparticle By Well-Tempered Metadynamics". The Journal of Physical Chemistry B (2018): https://doi.org/10.1021/acs.jpcb.8b05717.
    10.1021/acs.jpcb.8b05717
  46. Ferreira, Lino. "A nanoformulation for the preferential accumulation in adult neurogenic niches". Journal of Controlled Release (2018): http://dx.doi.org/10.1016/j.jconrel.2018.06.013.
    10.1016/j.jconrel.2018.06.013
  47. Miguel M. Lino; Susana Simões; Andreia Vilaça; Helena Antunes; Alessandra Zonari; Lino Ferreira. "Modulation of Angiogenic Activity by Light-Activatable miRNA-Loaded Nanocarriers". ACS Nano (2018): https://doi.org/10.1021/acsnano.7b07538.
    10.1021/acsnano.7b07538
  48. Adrián Jiménez-Balsa; Sandra Pinto; Emanuel Quartin; Miguel M. Lino; Vitor Francisco; Lino Ferreira. "Nanoparticles Conjugated with Photocleavable Linkers for the Intracellular Delivery of Biomolecules". Bioconjugate Chemistry (2018): https://doi.org/10.1021/acs.bioconjchem.7b00820.
    10.1021/acs.bioconjchem.7b00820
  49. Ferreira, Lino. "STROKE34 Study Protocol: A Randomized Controlled Phase IIa Trial of Intra-Arterial CD34+ Cells in Acute Ischemic Stroke". Frontiers in Neurology (2018): http://dx.doi.org/10.3389/fneur.2018.00302.
    10.3389/fneur.2018.00302
  50. Patricia R. Pitrez; Luís Estronca; Helena Vazão; Anne-Laure Egesipe; Amélie Le Corf; Claire Navarro; Nicolas Lévy; et al. "Substrate Topography Modulates Cell Aging on a Progeria Cell Model". ACS Biomaterials Science & Engineering (2018): https://doi.org/10.1021/acsbiomaterials.8b00224.
    10.1021/acsbiomaterials.8b00224
  51. Ferreira, Lino. "Intravenous administration of retinoic acid-loaded polymeric nanoparticles prevents ischemic injury in the immature brain". Neuroscience Letters (2018): http://dx.doi.org/10.1016/j.neulet.2018.02.066.
    10.1016/j.neulet.2018.02.066
  52. Ferreira, Lino. "MicroRNA-124-loaded nanoparticles increase survival and neuronal differentiation of neural stem cells in vitro but do not contribute to stroke outcome in vivo". PLOS ONE (2018): http://dx.doi.org/10.1371/journal.pone.0193609.
    10.1371/journal.pone.0193609
  53. Ferreira, Lino. "Endothelial Progenitor Cells influence acute and subacute stroke hemodynamics". Journal of the Neurological Sciences (2018): http://dx.doi.org/10.1016/j.jns.2017.12.028.
    10.1016/j.jns.2017.12.028
  54. Sargento-Freitas J; Aday S; Nunes C; Cordeiro M; Gouveia A; Silva F; Machado C; et al. "Endothelial progenitor cells enhance blood-brain barrier permeability in subacute stroke.". Neurology (2018): http://europepmc.org/abstract/med/29237797.
    10.1212/wnl.0000000000004801
  55. Pinho S; Macedo MH; Rebelo C; Sarmento B; Ferreira L. "Stem cells as vehicles and targets of nanoparticles.". Drug discovery today (2018): http://europepmc.org/abstract/med/29337203.
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  127. Zumbuehl, A.; Ferreira, L.; Kuhn, D.; Astashkina, A.; Long, L.; Yeo, Y.; Iaconis, T.; et al. "Antifungal hydrogels". Proceedings of the National Academy of Sciences of the United States of America 104 32 (2007): 12994-12998. http://www.scopus.com/inward/record.url?eid=2-s2.0-34548767010&partnerID=MN8TOARS.
    10.1073/pnas.0705250104
  128. Ferreira, L.; Figueirecio, M.M.; Gil, M.H.; Ramos, M.A.. "Structural analysis of dextran-based hydrogels obtained chemoenzymatically". Journal of Biomedical Materials Research - Part B Applied Biomaterials 77 1 (2006): 55-64. http://www.scopus.com/inward/record.url?eid=2-s2.0-33645418697&partnerID=MN8TOARS.
    10.1002/jbm.b.30394
  129. Khademhosseini, A.; Ferreira, L.; Blumling III, J.; Yeh, J.; Karp, J.M.; Fukuda, J.; Langer, R.. "Co-culture of human embryonic stem cells with murine embryonic fibroblasts on microwell-patterned substrates". Biomaterials 27 36 (2006): 5968-5977. http://www.scopus.com/inward/record.url?eid=2-s2.0-33748769776&partnerID=MN8TOARS.
    10.1016/j.biomaterials.2006.06.035
  130. Karp, J.M.; Ferreira, L.S.; Khademhosseini, A.; Kwon, A.H.; Yeh, J.; Langer, R.S.. "Cultivation of human embryonic stem cells without the embryoid body step enhances osteogenesis in vitro". Stem Cells 24 4 (2006): 835-843. http://www.scopus.com/inward/record.url?eid=2-s2.0-33745504422&partnerID=MN8TOARS.
    10.1634/stemcells.2005-0383
  131. Maia, J.; Ferreira, L.; Carvalho, R.; Ramos, M.A.; Gil, M.H.. "Synthesis and characterization of new injectable and degradable dextran-based hydrogels". Polymer 46 23 (2005): 9604-9614. http://www.scopus.com/inward/record.url?eid=2-s2.0-26844528911&partnerID=MN8TOARS.
    10.1016/j.polymer.2005.07.089
  132. Ferreira, L.; Evangelista, M.B.; Martins, M.C.L.; Granja, P.L.; Esteves, J.L.; Barbosa, M.A.. "Improving the adhesion of poly(ethylene terephthalate) fibers to poly(hydroxyethyl methacrylate) hydrogels by ozone treatment: Surface characterization and pull-out tests". Polymer 46 23 (2005): 9840-9850. http://www.scopus.com/inward/record.url?eid=2-s2.0-26844540116&partnerID=MN8TOARS.
    10.1016/j.polymer.2005.08.033
  133. Ferreira, L.; Gil, M.H.; Cabrita, A.M.S.; Dordick, J.S.. "Biocatalytic synthesis of highly ordered degradable dextran-based hydrogels". Biomaterials 26 23 (2005): 4707-4716. http://www.scopus.com/inward/record.url?eid=2-s2.0-14844303889&partnerID=MN8TOARS.
    10.1016/j.biomaterials.2004.11.051
  134. Ferreira, L.; Rafael, A.; Lamghari, M.; Barbosa, M.A.; Gil, M.H.; Cabrita, A.M.S.; Dordick, J.S.. "Biocompatibility of chemoenzymatically derived dextran-acrylate hydrogels". Journal of Biomedical Materials Research - Part A 68 3 (2004): 584-596. http://www.scopus.com/inward/record.url?eid=2-s2.0-1342280525&partnerID=MN8TOARS.
  135. Ferreira, L.; Ramos, M.A.; Dordick, J.S.; Gil, M.H.. "Influence of different silica derivatives in the immobilization and stabilization of a Bacillus licheniformis protease (Subtilisin Carlsberg)". Journal of Molecular Catalysis B: Enzymatic 21 4-6 (2003): 189-199. http://www.scopus.com/inward/record.url?eid=2-s2.0-0347297355&partnerID=MN8TOARS.
    10.1016/S1381-1177(02)00223-0
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    10.1016/S0142-9612(02)00132-1
  137. Ferreira, L.; Gil, M.H.; Carvalho, R.; Geraldes, C.F.G.C.; Kim, D.-Y.; Dordick, J.S.. "Biocatalytic polytransesterification of inulin with divinyladipate". Chemistry of Materials 14 10 (2002): 4009-4011. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036799646&partnerID=MN8TOARS.
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    10.1021/bp0255457
  139. Ferreira, Lino. "Design of a drug-delivery system based on polyacrylamide hydrogels. Evaluation of structural properties". Chemical educator (2001): http://link.springer.com/article/10.1007%2Fs00897010461a.
    10.1007/s00897010461a
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  141. Ferreira, L.; Vidal, M.M.; Geraldes, C.F.G.C.; Gil, M.H.. "Preparation and characterization of gels based on sucrose modified with glycidyl methacrylate". Carbohydrate Polymers 41 1 (2000): 15-24. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033908440&partnerID=MN8TOARS.
    10.1016/S0144-8617(99)00064-8
Capítulo de livro
  1. Deolinda Santinha, Andreia Vilaça, Alessandro Ori, Lino Ferreira. Autor correspondente: Deolinda Santinha, Andreia Vilaça, Alessandro Ori, Lino Ferreira. "The Extracellular Matrix in Cardiovascular Aging¿". In ¿Aging: From Fundamental Biology to Societal Impact, editado por Paulo Oliveira and João Malva. Elsevier, 2022.
    No prelo
  2. Ali Khademhossein, Nureddin Ashammakhi, Jeffrey M. Karp, Sharon Gerecht-Nir, Lino Ferreira, Nasim Annab, Mohammad Ali Da. "Embryonic stem cells as a cell source for tissue engineering". In Principles of Tissue Engineering (Fifth edition), 2020, pages 467-490. https://doi.org/10.1016/B978-0-12-818422-6.00027-7, editado por Robert Lanza,; Joseph P. Vacanti; Robert Langer; Anthony Atala, 467-490. Academic Press, 2020.
    Publicado
  3. Rai, Akhilesh; Comune, Michela; Ferreira, Lino. "Nanoparticle-Based Drug Delivery Systems: Promising Approaches Against Bacterial Infections". In Antibacterial Drug Discovery to Combat MDR, 605-633. Springer Singapore, 2019.
    10.1007/978-981-13-9871-1_27
  4. Pitrez, Patrícia R.; Aires, Helena R.; Tomé, Inês; Ferreira, Rita Sá; Ferreira, Lino. "Physiological and Pathological Vascular Aging". In Biophysical Regulation of Vascular Differentiation and Assembly, 51-72. Springer International Publishing, 2018.
    10.1007/978-3-319-99319-5_3
  5. Estronca, L.; Ferreira, L.. "Stem Cells for the Regeneration of Chronic Wounds". In Stem Cell Manufacturing, 291-312. Elsevier, 2016.
    10.1016/b978-0-444-63265-4.00013-3
Livro
  1. Luo, Y.; Engelmayr, G.; Auguste, D.T.; da Silva Ferreira, L.; Karp, J.M.; Saigal, R.; Langer, R.. 3D Scaffolds. 2013.
    10.1016/B978-0-12-398358-9.00024-0
  2. Khademhosseini, A.; Karp, J.M.; Gerecht-Nir, S.; Ferreira, L.; Annabi, N.; Sirabella, D.; Vunjak-Novakovic, G.; Langer, R.. Embryonic Stem Cells as a Cell Source for Tissue Engineering. 2013.
    10.1016/B978-0-12-398358-9.00032-X
  3. Spelke, D.P.; Ortmann, D.; Khademhosseini, A.; Ferreira, L.; Karp, J.M.. Methods for embryoid body formation: The microwell approach. 2011.
    10.1007/978-1-60761-962-8_10
  4. Karp, J.M.; Mahdavi, A.; Ferreira, L.S.; Khademhosseini, A.; Langer, R.. Part C: Directed Differentiation of Human Embryonic Stem Cells into Osteoblasts Cells. 2007.
    10.1002/9780470511619.ch13c
  5. Khademhosseini, A.; Karp, J.M.; Gerecht, S.; Ferreira, L.; Vunjak-Novakovic, G.; Langer, R.. Embryonic stem cells as a cell source for tissue engineering. 2007.
    10.1016/B978-012370615-7/50036-6
  6. Luo, Y.; Engelmayr, G.; Auguste, D.T.; Ferreira, L.D.S.; Karp, J.M.; Saigal, R.; Langer, R.. Three-dimensional scaffolds. 2007.
    10.1016/B978-012370615-7/50029-9

Propriedade Intelectual

Patente
  1. Ferreira, Lino. 2020. "Light triggerable gene editing formulation, in vivo editing method, and used thereof".
    Pendente
  2. Ferreira, Lino. 2020. "A light-triggerable nanoparticle library of formulations for the controlled release of RNAs".
    Pendente
  3. Ferreira, Lino. 2018. "Composition and method of stem cells for preservation of cardiac tissue".
  4. Ferreira, Lino. 2017. "Use of umbilical cord blood derived exosomes for tissue repair".
    Concedida/Emitida
  5. Ferreira, Lino. 2015. "Antimicrobial complexes".
    Pendente
  6. Ferreira, Lino. 2014. "A human blood-brain barrier model derived from stem cells".
    Concedida/Emitida
  7. Ferreira, Lino. 2014. "Antimicrobial coating compositions".
    Concedida/Emitida
  8. Ferreira, Lino. 2013. "Differentiated cell population of endothelial cells derived from human pluripotent stem cells, composition, system, kit and uses thereof".
    Concedida/Emitida
  9. Ferreira, Lino. 2012. "Nanoparticles and uses thereof".
    Concedida/Emitida
  10. Ferreira, Lino. 2011. "Composition and method to improve the therapeutic effect of stem cells".
    Concedida/Emitida
  11. Ferreira, Lino. 2010. "Antimicrobial nanoparticle conjugate".
    Retirada
  12. Ferreira, Lino. 2009. "Adhesive articles".
    Concedida/Emitida
  13. Ferreira, Lino. 2009. "Particulate delivery vehicles for embryoid bodies".
    Concedida/Emitida
  14. Ferreira, Lino. 2007. "Development of Multifunctional Photocurable Degradable Elastomers".
    Concedida/Emitida
  15. Ferreira, Lino. 2007. "Amplification of cell populations from embryonic stem cells".
    Concedida/Emitida
  16. Ferreira, Lino. 2007. "Coating of devices with effector compounds".
    Concedida/Emitida
  17. Ferreira, Lino. 2007. "Formation of vascular networks using human embryonic stem cells".
    Retirada
  18. Ferreira, Lino. 2007. "Medical devices and coatings with non-leaching bioactive peptides".
    Concedida/Emitida

Outros

Outra produção
  1. Differentiation of human induced-pluripotent stem cells into smooth muscle cells. 2021. Patricia R. Pitrez; Lino Ferreira. https://doi.org/10.21203/rs.3.pex-964/v1.
    10.21203/rs.3.pex-964/v1
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2021/09/05 Modulation of stem cells using nanotechnologies
31st Conference of the European Society for Biomaterials (ESB) together with the 43rd Annual Congress of the Iberian Society of Biomechanics and Biomaterials (SIBB) (Virtually)
2020/12/18 Non-coding RNA-engineered extracellular vesicles for cardiac regeneration
Portuguese Network of Extracellular Vesicles (Porto)
2020/12/04 O envelhecimento visto sobre o olhar da medicina regenerativa EMBS
(Coimbra, Portugal)
2020/06/23 O envelhecimento visto sobre o olhar da medicina regenerativa Ciclo de conferencias CULTURGEST sobre a temática “LIFE>TIME: a vida maior que o tempo”
Culturgest (Lisboa, Portugal)
2019/11/22 Physiological and pathological cardiovascular ageing: models and therapies
Sociedade Portuguesa de Cirurgia Cardiotorácica e Vascular (Albufeira, Portugal)
2019/11/06 The kinetics of small extracellular vesicle delivery impacts skin tissue regeneration
5th GEIVEX Symposium (Granada, Espanha)
2019/10/10 Prolonged intracellular accumulation of light inducible nanoparticles in leukemia cells allows their remote activation
SPCE-TC (Lisboa, Portugal)
2019/07/23 Light-activatable (nano)materials for cell regulation
41st Annual International conference of the IEEE Engineering in Medicine and Biology Society (Berlin, Alemanha)
2019/06/28 Physiological and pathological cardiovascular ageing: models and therapies Ageing conference
(Coimbra, Portugal)
2019/06/28 Physiological and pathological cardiovascular ageing: models and therapies Ageing: models, mechanisms and therapies
(Coimbra, Portugal)
2019/06/23 Light-activatable (nano)materials for cell regulation Nanofar: European doctorate in nanomedicine
(Angers, França)
2019/05/22 Therapies and stem cell-based models for cardiovascular applications 53rd ESCI2019
Annual scientific meeting of the European Society for Clinical Investigation (Coimbra, Portugal)
2019/04/01 Mechanical forces in vascular cell maturation and disease Mechanobiology of migrating cells: from basic science to the clinic
Cost Action CA15214 (EuroCellNet) working group meeting (Coimbra, Portugal)
2019/01/31 Light-activatable (nano)materials for cell regulation Advanced theranostic nanomedicine in oncology
ERC Starting Grant SLaMM Workshop (Pisa, Itália)
2019/01/16 Light-activatable (nano)materials for cell regulation Nanotechnology for therapy and diagnostics
International Iberian nanotechnology Laboratory (Braga, Portugal)
2018/11/07 Induced pluripotent stem cell-derived tissues for drug screening and disease modeling
Sociedade Portuguesa de Biologia de Desenvolvimento (Porto, Portugal)
2018/10/11 Engineered cardiac tissues and stem cell-based therapies for cardiovascular applications Reunião Anual da APIC'18
(Troia, Portugal)
2018/09/09 Light-activatable (nano)materials for cell regulation
European Society of Biomaterials (Maastricht, Países Baixos)
2018/07/04 Innovative therapies for age-associated diseases Programa Ciencia
(Lisboa, Portugal)
2018/06/27 Ageing vascular model from iPSCs for the identification of new therapies Workshop ERA Chair
(Coimbra, Portugal)
2018/02/05 Peptide-conjugated nanomaterials for biomedical applications
16th Iberian Peptide Meeting/ 4th ChemBio Group meeting (Barcelona, Espanha)
2018/01/14 Drug delivery in regenerative medicine Tailoring drug delivery systems to the patients needs
XII Spanish-Portuguese conference on controlled drug delivery (Coimbra, Portugal)
2017/09/30 ERA@UC: Enhancing research in aging at the University of Coimbra Congresso Nacional de Medicina Geral e Familiar
(Vila Real, Portugal)
2017/04/08 Stem cell-based models for cardiovascular diseases Symposium on bioengineering
Universidade do Porto (Porto, Portugal)

Orientação

Título / Tema
Papel desempenhado
Curso (Tipo)
Instituição / Organização
2022/01/01 - Atual Targeted Formulations for Cell Senescence
Coorientador de Andreia Marques
Universidade de Coimbra, Portugal
2021/11/01 - Atual Unravelling and treating blood-brain barrier dysfunction upon ageing
Coorientador de João Pedro Ferreira da Costa Novo
Universidade de Coimbra, Portugal
2019/04/01 - Atual Engineered formulations for gene editing
Coorientador de Angela Barrera
Universidade de Coimbra Faculdade de Medicina, Portugal
2018/09/01 - Atual New platforms for brain targeting and modulation
Coorientador de Ines Maria Cunha Albino
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2018/09/01 - Atual Gene editing nanoformulations for brain applications
Coorientador de Francesca Tomatis
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2016/12 - Atual Engineering an aged cardiac tissue from human pluripotent stem cells
Orientador de Luís Miguel de Almeida Monteiro
Biologia Experimental e Biomedicina (Doutoramento)
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2016/08 - Atual A multi-approach platform to identify biomolecules for cardiac regeneration
Orientador de Andreia Pinheiro Vilaça
Biologia Experimental e Biomedicina (Doutoramento)
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2015/10 - Atual Cardiac microtissues for disease modeling and drug screening
Orientador de Deolinda da Conceição Ribafeita Santinha
Envelhecimento e Doenças Crónicas (Doutoramento)
Universidade de Coimbra Faculdade de Medicina, Portugal
2016/08/01 - 2022/03/29 Vascular cell senescence: triggers and therapeutic strategies
Orientador de Rita Rodrigues Sá Ferreira
Biotecnologia (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2016/08/01 - 2022/02/21 Extracellular vesicles as platforms for therapeutic microRNA delivery
Orientador de Ricardo Cerqueira de Abreu
Biologia Experimental e Biomedicina (Doutoramento)
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2012/03 - 2021/01/11 Biocompatible nanoparticles to modulate cell activity
Orientador de Josephine Blersch
Biologia Experimental e Biomedicina (Doutoramento)
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2015/01 - 2019/12 Light-triggerable delivery of a gene edition system
Orientador de Catarina Araujo Gomes Rebelo
Bioengenharia (Doutoramento)
Universidade Nova de Lisboa, Portugal
2018/06 - 2019/09 Investigation of the Blood-Brain Barrier ageing for the development of an in vitro model
Orientador de Ana Carolina Silva Caetano
Biologia Celular e Molecular (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2013/03 - 2018/12 Modulation of the hematopoietic stem cell niche by photo-triggerable nanoparticles
Coorientador de Emanuel Nery de Oliveira Quartin Costa
Bioengenharia (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2011/08 - 2018/11 Endothelial precursor cells in neoangiogenesis of acute ischemiq stroke
Orientador de João André Sargento Araujo de Freitas
Ciências da Saúde
Universidade de Coimbra Faculdade de Medicina, Portugal
2013/09 - 2018/10 Engineering human in vitro cardiac tissue models for preclinical research
Coorientador de Bernardo Martins da Cunha Abecasis
Engenharia Biológica (Doutoramento)
Universidade Nova de Lisboa, Portugal
2017/07 - 2018/09 Urine extracellular vesicles: waste or a powerful tool?
Coorientador de Carlos Alberto Gaspar de Jesus
Investigação Biomédica (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2017/05 - 2018/09 Breaking the barriers of HFpEF: a New "Blood Vessel on a Chip" Model
Coorientador de Ines Tomé Ribeiro
Investigação Biomédica (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2017/05 - 2018/09 High-throughput identification of polymeric compounds that affect human vascular cell senescence
Coorientador de Helena Isabel Reis Aires
Biologia Celular e Molecular (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2017/09 - 2018/07 Encapsulation of vascular cells in fibrin gels: assessment of cell viability, proliferation, migration and organization
Orientador de Rita Alexandra Lopes dos Santos
Bioquímica (Licenciatura/Bacharelato)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2013/01 - 2017/12 MicroRNA-124-loaded nanoparticles as a new promising therapeutic tool for neural stem cell-based brain repair strategies
Coorientador de Claudia Marisa Monteiro Saraiva
Bioengenharia (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2012/07 - 2017/12 Vascular organ-on-a-chip platforms for disease modeling
Orientador de João Carlos Ribas de Almeida
Biologia Experimental e Biomedicina (Doutoramento)
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2012/09 - 2017/10 Stem cell and stem cell-free based therapeutics against myocardial infarction
Orientador de Ivana Kostic
Bioengenharia (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2016/05 - 2017/06 Exosomes-based therapy for stroke
Coorientador de Antonio José da Silva Santinha
Biologia Celular e Molecular (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2012/02 - 2017/06 Light-triggerable nanomaterials for the delivery of biomolecules
Orientador de Miguel Maria da Fonseca Miranda Ferreira Lino
Biociências (Doutoramento)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2011/09 - 2017/02 Brain-like endothelial cells derived from stem cells to study BBB development and targeting
Orientador
Biologia Experimental e Biomedicina (Doutoramento)
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2015/05 - 2016/10 Development of a photo-triggerable nanoparticle for efficient intracellular delivery of siRNA
Orientador
Bioengenharia (Mestrado)
Universidade do Porto, Portugal
2015/05 - 2016/10 Evaluation of the therapeutic potential of piezoelectric fibers-coated thin films for the treatment of myocardial infarction
Coorientador de Luis Miguel de Almeida Monteiro
Bioengenharia (Mestrado)
Universidade do Porto, Portugal
2015/05 - 2016/07 Prevention of Intravascular Catheter-Related Infections
Coorientador de Micaela Alexandra Machado Querido
Engenharia Biomédica (Mestrado)
Universidade do Porto, Portugal
2011/12 - 2016/06 Wound healing and pro-angiogenic properties of LL37-conjugated nanoparticles
Orientador de Michela Comune
Biociências (Doutoramento)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2010/09 - 2016/06 Cardiac tissue constructs for drug screening
Orientador de Pedro José Azeredo de São Bento Gouveia
Biologia Experimental e Biomedicina (Doutoramento)
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2010/09 - 2016/06 Bioengineering platform to modulate the activity of smooth muscle cells derived from Progeria induced pluripotent stem cells
Orientador de Patrícia Raquel Pinheiro Pitrez Pereira
Bioengenharia (Doutoramento)
Universidade do Minho, Portugal
2009/09 - 2015/01 Leukemia cells modulation by light-activatable nanoparticles
Coorientador de Carlos Samuel Marques Boto
Engenharia Química (Doutoramento)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2008/09 - 2013/12 Nanomaterials for Mirna Delivery and Non-Invasive Imaging in Cardiovascular Regeneration
Orientador de Renata Sofia Mota Gomes
Bioquímica (Doutoramento)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2008/09 - 2013/12 Platforms to modulate the activity of hematopoietic stem cells and their progenies
Orientador de Sezin Aday
Bioengenharia (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2008/09 - 2013/07 Platforms for tissue reconstruction: compliant biomaterials for local drug delivery and tissue adhesion
Orientador de Maria José Maio Nunes Pereira
Bioengenharia (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2011/11 - 2013/04 High-throughput screening to discover compounds that enhance the proliferative and metabolic activity of tendon or ligament cells and improve the proliferation of endothelial cells
Coorientador de Tânia Luisa Barbosa Barata
Biotecnologia para as Ciências da Saúde (Mestrado)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2008/03 - 2012/12 Approaches to improve the differentiation, maturation and biological activity of vascular cells derived from stem cells
Orientador de Helena Sofia Esmeraldo de Campos Vazão
Biologia (Licenciatura/Bacharelato)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2007/09 - 2012/11 Permanent antifungal materials and coatings: bioactivity and cytotoxicity characterization
Orientador
Biotecnologia (Doutoramento)
Universidade de Lisboa, Portugal

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação)
Instituição / Organização
2021/09/05 - 2021/09/09 Symposium “Nanostructure-based biomaterials: design and biological interactions”, 31st conference of the European Society of Biomaterials (ESB), September 5-9th, online (2021/09/05 - 2021/09/09)
Conferência (Outra)
European Society of Biomaterials, França
2021/06/09 - 2021/06/11 Symposium “Regenerative and genomic medicine”, 55th annual ESCI scientific meeting, 9-11 June, online (2021/06/09 - 2021/06/11)
Conferência (Outra)
European Society for Clinical Investigation, Países Baixos
2021/06/01 - 2021/06/04 Symposium “Cardiovascular ageing and regenerative medicine”, 6th World congress of TERMIS, June 1-4th, online (2021/06/01 - 2021/06/04)
Conferência (Outra)
Tissue Engineering and Regenerative Medicine International Society, Estados Unidos
2020/05/27 - 2020/05/29 Symposium entitled "Stem cells & cell therapies" (2020/05/27 - 2020/05/29)
Conferência (Outra)
European Society for Clinical Investigation, Países Baixos
2019/06/28 - 2019/06/29 International conference on “Ageing: models, mechanisms and therapies” (2019/06/28 - 2019/06/29)
Conferência (Presidente da Comissão Organizadora)
Universidade de Coimbra Faculdade de Medicina, Portugal
2019/05/22 - 2019/05/24 Symposium “Gene and Cell therapy: from fundamental science to the clinic”, European Society for Clinical Investigation, May 22-24th, Coimbra (2019/05/22 - 2019/05/24)
Conferência (Outra)
European Society for Clinical Investigation, Países Baixos
2018/09/10 - 2018/09/13 Symposium “Nanostructured biomaterials for cell regulation”, European Society of Biomaterials, September 10-13th, Maastricht, Netherlands (2018/09/10 - 2018/09/13)
Conferência (Outra)
European Society of Biomaterials, França
2018/06/27 - 2018/06/27 Workshop on “Ageing: models and therapies” (2018/06/27 - 2018/06/27)
Oficina (workshop) (Presidente da Comissão Organizadora)
Universidade de Coimbra Faculdade de Medicina, Portugal
2016/07/07 - 2016/07/08 German-Portuguese student Workshop on “Translation in Biomaterials and Stem Cell Research” (2016/07/07 - 2016/07/08)
Oficina (workshop) (Presidente da Comissão Organizadora)
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2016/06/27 - 2016/06/27 Stem cell workshop: from basic research to clinical applications (2016/06/27 - 2016/06/27)
Oficina (workshop) (Membro da Comissão Organizadora)
Centro Hospitalar e Universitario de Coimbra EPE Campus dos Hospitais da Universidade de Coimbra, Portugal
2014/12/17 - 2014/12/20 Symposium entitled "Tissue engineering and regenerative medicine"- XVIII Congress of the Portuguese Biochemical Society, 17-20 December, Coimbra, Portugal (2014/12/17 - 2014/12/20)
Congresso (Outra)
Sociedade Portuguesa de Bioquímica, Portugal
2014/11/28 - 2014/11/29 “Heart without Borders”- International conference in cardiovascular development, disease and repair (2014/11/28 - 2014/11/29)
Conferência (Membro da Comissão Organizadora)
2014/03/24 - 2014/03/24 Workshop on Stem cells: from basic research to therapeutic applications, Centro do Sangue e Transplantação de Coimbra (2014/03/24 - 2014/03/24)
Oficina (workshop) (Presidente da Comissão Organizadora)
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2013/09/09 - 2013/09/10 German-Portuguese student Workshop on “Matrix Engineering meets Stem Cell Therapy” (2013/09/09 - 2013/09/10)
Oficina (workshop) (Presidente da Comissão Organizadora)
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2013/07/19 - 2013/07/20 First International Conference on Stem Cells for Drug Screening and Regenerative Medicine (2013/07/19 - 2013/07/20)
Conferência (Presidente da Comissão Organizadora)
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2011/04/28 - 2011/04/29 6th Annual International Meeting of the Portuguese Society for Stem Cells and Cellular Therapies (2011/04/28 - 2011/04/29)
Congresso (Presidente da Comissão Organizadora)
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2010/06/18 - 2010/06/18 Fourth Annual Workshop on the Business-Government Interface: Personalized Medicine (2010/06/18 - 2010/06/18)
Oficina (workshop) (Presidente da Comissão Organizadora)
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2009/06/02 - 2009/06/02 Third Annual Workshop on the Business-Government Interface: Challenges in Cell and Gene Therapies (2009/06/02 - 2009/06/02)
Oficina (workshop) (Presidente da Comissão Organizadora)
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Participação em evento

Descrição da atividade
Tipo de evento
Nome do evento
Instituição / Organização
2003/06/28 - 2003/07/04 4th Advanced Course in Cell-Material Interactions
Outro
4th Advanced Course in Cell-Material Interactions

Júri de grau académico

Tema
Tipo de participação
Nome do candidato (Tipo de grau)
Instituição / Organização
2022/01/07 Bioengineering an Immunomodulatory Microenvironment for Bone Healing
Arguente principal
Mafalda Bessa Martins Gonc¸alves (Doutoramento)
Universidade do Porto, Portugal
2021/05/28 Extracellular vesicles at the heart of cell-cell communication
Arguente principal
Lara Ottaviani (Doutoramento)
Universiteit Maastricht Department of Pharmacology and Toxicology, Países Baixos
2021/05/25 Role of cholesteryl-hemiesters in the etiology of atherogenesis
Arguente principal
Liliana Teresa da Silva Alves (Doutoramento)
Universidade Nova de Lisboa, Portugal
2021/04/27 Development of theranostic nanostructures for early stages of Alzheimer ´s Disease
Arguente principal
Manuel Rodríguez Pérez (Doutoramento)
Universidade de Santiago de Compostela, Espanha
2021/03/19 Development of Human Pluripotent Stem Cell-derived Cardiovascular Microtissues for Cardiotoxicity Screening
Arguente principal
Mariana da Mota Veiga de Araujo Branco (Doutoramento)
Universidade de Lisboa, Portugal
2021/01/19 Bioprocess development for scalable generation of functional liver micro- tissues/organoids from human pluripotent stem cells
Arguente principal
Saeed Abbasalizadeh (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2020/06/26 New Active Nanomaterials for Stem Cell Differentiation in Bone Regeneration
Arguente principal
Márcia Tojeira Tavares (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2020/05/22 Developing cellular models for hypertrophic cardiomyopathy
Arguente principal
Marta de Jesus Ribeiro (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2020/04/28 Tuning extracellular cues to regulate epithelial cell phenotype
Arguente principal
Maria João Pardelha da Cruz (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2020/03/23 Molecular mechanism of horizontal mitochondrial transfer from stroll cells to cancer cells with damaged mitochondrial DNA
Arguente
Ana Raquel Ligeiro Coelho (Doutoramento)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2020/02/14 Induced pluripotent stem cells as a new approach in therapy for stroke
Arguente principal
Esteban López Arias (Doutoramento)
Universidade de Santiago de Compostela, Espanha
2020/01/07 Three-dimensional culture systems for the study of human pluripotent stem cells: microarrays and spheroids
Arguente
Jorge Filipe da Conceição Pascoal (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2019/12/12 Gold Nanoparticles to Tackle Drug Resistance in Cancer
Arguente principal
Pedro Miguel Pinto Gonçalves Gouveia Pedrosa (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2019/05/28 Novel therapeutic approach to amyotrophic lateral sclerosis: targeting neurotoxic astrocytes before transplantation
Arguente
Cátia Sofia Vicente Gomes (Doutoramento)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2019/05/15 Modeling Radiation Injury and Countermeasure Drug Responses in a Human Intestine Chip
Arguente principal
Sasan Jalili Firoozinezhad (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2019/04/05 Study of Biophysical Interactions and Antibody Bioactivity of Bevacizumab Encapsulated into Nanoparticles Towards its Controlled Release
Arguente principal
Flavia Sousa (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2018/12/21 Insights into gold nanoparticles functionalized with cysteine-terminated cecropia mellitus and cathelicidin-derived antimicrobial peptides- a computational approach
Vogal
André Filipe Simões Ferreira (Doutoramento)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2018/09/18 A therapeutic epicardial reservoir for the treatment of cardiac disease
Arguente principal
William White (Doutoramento)
Trinity College Dublin School of Medicine, Irlanda
2018/07 Identification of native cardiogenic niche-feature(s) for improved cardiac cell response: the role of the extracellular matrix
Arguente principal
Ana Catarina de Andrade e Silva (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2018/05 CLAMP - CLick chemistry as a tool to create AntiMicrobial Peptide-based materials
Arguente principal
Mariana Moreira da Silva Alves Barbosa (Doutoramento)
Universidade do Porto Faculdade de Engenharia, Portugal
2017/12 VASCULAR ORGAN-ON-A-CHIP PLATFORMS FOR DISEASE MODELING
Orientador
João Carlos Ribas de Almeida (Doutoramento)
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2017/12 Effect of industrial GMP human plasma derived supplement on hMSC behaviour
Vogal
Maura Cimino (Doutoramento)
Universidade do Porto Faculdade de Engenharia, Portugal
2017/10 Stem cell and stem cell-free based therapeutics against myocardial infarction
Orientador
Ivana Kostic (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2017/07 Novel nanoparticle-based drug delivery system for neural stem cell targeting and differentiation
Arguente principal
Dario Carradori (Doutoramento)
Université catholique de Louvain - Mons, Bélgica

Université d'Angers, França
2017/06 Light-triggerable nanomaterials for the delivery of biomolecules
Orientador
Miguel Maria da Fonseca Miranda Ferreira Lino (Doutoramento)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2017/03 Tribos transformation of Escherichia coli JM109
Arguente principal
Gabriel Pinto Mendes (Doutoramento)
Universidade do Minho, Portugal
2017/02 Bioprocessing of human pluripotent stem cells for cardiac cell therapy and pre-clinical research
Arguente principal
Claudia Susana Pedreira Correia (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2017/02 Brain-like endothelial cells derived from stem cells to study BBB development and targeting
Orientador
Catarina Oliveira Praça de Almeida (Doutoramento)
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2017/01 Scalable manufacturing of mesenchymal stem/stromal cells for cell therapies and the role of the Notch signaling pathway in the human hematopoietic system
Arguente principal
Antonio Maria Santa Marta de Soure (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2016/09 Cicatrização de feridas de pele e actividade pro-angiogénica das nanopartículas conjugadas com LL37
Orientador
Michela Comune (Doutoramento)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2016/07 Development of an injectable dextrin hydrogel for bone regeneration
Arguente principal
Dina Maria Morais da Silva (Doutoramento)
Universidade do Minho, Portugal
2016/07 Role of Ccbe1 during cardiac differentiation of mouse ESCs
Arguente principal
Tiago Manuel Santos Justo (Doutoramento)
Universidade do Algarve, Portugal
2016/06 Cardiac tissue constructs for drug screening
Orientador
Pedro José Azeredo de São Bento Gouveia (Doutoramento)
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2016/06 Bioengineering platforms to modulate the activity of smooth muscle cells derived from progeria-induced pluripotent stem cells
Orientador
Patricia Raquel Pinheiro Pitrez Pereira (Doutoramento)
Universidade do Minho, Portugal
2016/05 Human Pluripotent Stem Cell Signaling and Cardiac Lineage Commitment
Arguente principal
Tiago Miguel Peixoto Dias (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2015/12 Fine-tuning neurogenesis: microRNA regulatory networks
Arguente principal
Ana Luisa Silva Neves Morgado (Doutoramento)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2015/12 Oxazoline-based Antimicrobial Platforms for Water Treatment
Arguente principal
Vanessa Fernandes Gomes Correia (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2015/11 Surface-immobilized Antimicrobial Peptides (AMPs) for prevention of implant-related osteomyelitis
Arguente principal
Fabíola Maria Tavares Alves da Costa Moutinho (Doutoramento)
Universidade do Porto Faculdade de Engenharia, Portugal
2015/11 Engineered MRI nanoprobes based on superparamagnetic iron oxide nanoparticles
Arguente principal
Susana Isabel Conde Jesus Palma (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2015/01 Endothelial Progenitor Cells of Diabetic Patients with Acute Coronary Syndromes: Effects of Antidiabetic and Lipid Lowering Drugs
Vogal
Natália Sofia Claudio António (Doutoramento)
Universidade de Coimbra Faculdade de Medicina, Portugal
2015/01 Leukemia Cells Modulation By Light-Activatable Nanoparticles
Orientador
Carlos Samuel Marques Boto (Doutoramento)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2014/12 Polyurea-based Dendrimers Therapeutics
Vogal
Ana Rita Bernardo Restani Silva (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2014/12 Mecanismos moleculares subjacentes à biologia da pluripotência induzida
Vogal
Rodrigo Luiz dos Santos (Doutoramento)
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2014/11 Deconstruction CD44 - Engineering 3 D matrices to elucidate CD44 modulation in gastric malignancy
Arguente principal
Cristiana Tavares Branco da Cunha (Doutoramento)
Universidade do Porto Faculdade de Medicina, Portugal
2014/10 Desenvolvimento de Materiais Poliméricos para Inibição de Quorum Sensing
Arguente principal
Eliana Marisa dos Santos (Doutoramento)
Universidade de Aveiro, Portugal
2014/05 STUDY OF THE APPLICATION POTENTIAL OF SYNTHETIC AND NATURAL POLYMERIC COATINGS IN STEM CELL RESEARCH
Arguente principal
Ana Rubina Nóbrega Perestrelo (Doutoramento)
Universidade do Algarve, Portugal
2013/12 Desenvolvimento de Matrizes Biomiméticas como Substitutos de Pele Destinados ao Tratamento de Queimaduras
Arguente principal
Susana Raquel Rodrigues Gomes (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2013/12 Migration and differentiation of neuronal precursors in the postnatal brain: insights from the subventricular zone and cerebellum
Vogal
Maria Francisca Eiriz (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2013/12 PLATFORMS TO MODULATE THE ACTIVITY OF HEMATOPOIETIC STEM CELLS AND THEIR PROGENIES
Orientador
Sezin Aday (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2013/12 Nanomateriais, miRNA, imagem não-invasiva na regeneração cardiovascular
Orientador
Renata Sofia Mota Gomes (Doutoramento)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2013/09 Studies on high molecular weight poly(lactic acid) synthesis
Vogal
Dina Augusta Simões Marques (Doutoramento)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2013/07 Platforms for tissue reconstruction: compliant biomaterials for local drug delivery and tissue adhesion
Orientador
Maria José Maio Nunes Pereira (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2013/01 Protease-sensitive hydrogels as 3D cellular microenvironments
Arguente principal
Keila Beltrame Fonseca (Doutoramento)
Universidade do Porto Faculdade de Engenharia, Portugal
2012/12 Approaches to Improve the Differentiation, Maturation and Biological Activity of Vascular Cells Derived from Stem Cells.
Orientador
Helena Sofia Esmeraldo de Campos Vazão (Doutoramento)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2012/11 PERMANENT ANTIFUNGAL MATERIALS AND COATINGS: BIOACTIVITY AND CYTOTOXICITY CHARACTERIZATION
Orientador
Cristiana da Silva Oliveira Paulo (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2012/07 Molecular design of surfaces towards more effective anticoagulation strategies for blood-contacting medical devices
Arguente principal
Sidónio Ricardo da Cunha Freitas (Doutoramento)
Universidade do Porto Faculdade de Engenharia, Portugal
2012/07 Electrospun fibrous mats for skin and abdominal wall repair
Arguente principal
Maria Beatriz da Rocha Veleirinho (Doutoramento)
Universidade de Aveiro, Portugal
2012/04 Development of Bio-Hybrid Actuators
Arguente principal
Leonardo Ricotti (Doutoramento)
Scuola Superiore Sant'Anna, Itália
2012/04 EX VIVO ENGINEERED COMBINATORIAL u-ENVIRONMENTS FOR STEM CELL FATE STUDIES: THE BALANCE BETWEEN STEM CELL SELF-RENEWAL AND DIFFERENTIATION
Arguente principal
David Fernandes Braga Malta (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2012/02 Process Engineering of Liver Cells for Drug Testing Applications
Arguente principal
Rui Manuel Lucas Gameiro Domingues Tostões (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2011/12 Bioactive Beads for Local Modulation and Sensing of Cell Mechanical Environment in 3d Engineered Tissues
Arguente principal
Eunice Margarida Santos Costa (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2011/11 Exploring the crosstalk between mesenchymal stem cells and endothelial cells in bone tissue engineering
Arguente principal
Silvia Joana Bidarra dos Santos Lourenço (Doutoramento)
Universidade do Porto Faculdade de Engenharia, Portugal
2011/10 Recombinant expression and Activity of cationic antimicrobial peptides
Arguente principal
Reinaldo Rodrigues Ramos (Doutoramento)
Universidade do Minho, Portugal
2011/07/01 Role of the notch-delta signalling pathway on bone marrow-derived cells function during wound healing and tumor progression
Arguente
Francisco Landeck Moreira Manso Caiado (Doutoramento)
Universidade de Lisboa, Portugal
2011/07/01 Novel Approaches for the Isolation and Ex-vivo Expansion of Hematopoietic stem cells from human umbilical cord blood for Cell Therapy
Arguente
Pedro Miguel Zacarias Andrade (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2011/04/01 Drug Delivery Systems for Tissue Engineering Applications
Arguente
João Reina Maia e Silva (Doutoramento)
Universidade de Coimbra, Portugal
2011/02/11 Process Engineering of Stem Cells for Clinical Application
Arguente principal
Maria Margarida de Carvalho Negrão Serra (Doutoramento)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2010/01/12 Development of Structures Based on Bacterial Cellulose for the Production of Vascular Prostheses
Arguente
Fábia Karine Andrade (Doutoramento)
Universidade do Minho, Portugal
2009/12/01 Cell-Based Microarray Systems for Stem Cell Expansion and Differentiation
Arguente
Tiago Paulo Gonçalves Fernandes (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2008/01/12 Development and Characterization of Dextrin Based Hydrogels Use of Non-catalityc Domains for the Modification of Polysaccharides
Arguente principal
Joana Maria Freitas Carvalho (Doutoramento)
Universidade do Minho, Portugal

Arbitragem científica em conferência

Nome da conferência Local da conferência
2020/09/13 - 2020/09/14 First Meeting of the Portuguese Network on Extracellular Vesicles Universidade do Porto
2019/10/10 - 2019/10/12 11st Annual International Meeting of the Portuguese Society for Stem Cells and Cellular Therapies Universidade de Lisboa
2017/10/12 - 2017/10/14 10th Annual International Meeting of the Portuguese Society for Stem Cells and Cellular Therapies Universidade da Beira Interior
2017/02/16 - 2017/02/18 IEEE ENBENG'2017 - 5th Portuguese Meeting in Bioengineering Universidade de Coimbra
2015/10/15 - 2015/10/16 9th Annual International Meeting of the Portuguese Society for Stem Cells and Cellular Therapies Universidade Nova de Lisboa
2013/09/08 - 2013/09/09 8th Annual International Meeting of the Portuguese Society for Stem Cells and Cellular Therapies
2012/05/26 - 2012/05/27 7th Annual International Meeting of the Portuguese Society for Stem Cells and Cellular Therapies Universidade do Porto
2011/04/28 - 2011/04/29 6th Annual International Meeting of the Portuguese Society for Stem Cells and Cellular Therapies Universidade de Coimbra Centro de Neurociências e Biologia Celular
2010/05/20 - 2010/05/21 5th Annual International Meeting of the Portuguese Society for Stem Cells and Cellular Therapies Universidade do Minho
2009/04/29 - 2009/04/30 4th Annual International Meeting of the Portuguese Society for Stem Cells and Cellular Therapies Universidade de Lisboa Instituto Superior Tecnico
2008/04/23 - 2008/04/24 3rd Annual International Meeting of the Portuguese Society for Stem Cells and Cellular Therapies Universidade do Algarve

Arbitragem científica em revista

Nome da revista (ISSN) Editora
2019/11/01 - Atual Biomaterials Science RSC
2018 - 2018 Bioconjugate Chemistry (1520-4812) American Chemical Society
2018 - 2018 Nanoscale (2040-3372) The Royal Society of Chemistry
2018 - 2018 Theranostics (1838-7640) Ivyspring International Publisher
2017 - 2018 Small (1613-6829) WILEY-VCH
2016 - 2018 Advanced Materials (1521-4095) Wiley (John Wiley & Sons)
2017 - 2017 Advanced Functional Materials (1616-3028) Wiley (John Wiley & Sons)
2016 - 2017 Journal of Controlled Release (0168-3659) Elsevier
2011 - 2017 ACS Nano (1936-086X) American Chemical Society
2013 - 2016 Biomaterials (0142-9612) Elsevier
2012 - 2015 Acta Biomaterialia (1742-7061) Elsevier
2013 - 2013 Proceedings of the National Academy of Sciences (1091-6490) Proceedings of the National Academy of Sciences
2012 - 2012 Experimental Dermatology (1600-0625) Wiley (Blackwell Publishing)
2012 - 2012 Langmuir (1520-5827) American Chemical Society
2012 - 2012 Nature Methods (1548-7105) Springer Science and Business Media LLC
2012 - 2012 PLoS ONE (1932-6203) Public Library of Science
2011 - 2011 Journal of Cardiovascular Translational Research (1937-5395) Springer-Verlag
2009 - 2011 Journal of Biomaterials Science Polymer Edition (1568-5624) Informa UK (Taylor & Francis)
2009 - 2011 Journal of Tissue Engineering and Regenerative Medicine (1932-7005) Wiley (John Wiley & Sons)
2010 - 2010 Nature Materials (1476-4660) Springer Science and Business Media LLC
2009 - 2009 Current Stem Cell Research & Therapy (1574-888X) Bentham Science
2009 - 2009 Stem Cells International (1687-9678) Hindawi Publishing Corporation (Sage-Hindawi Access to Research)
2008 - 2008 Biotechnology Progress (1520-6033) Wiley (John Wiley & Sons)
2008 - 2008 Tissue Engineering (1076-3279) Mary Ann Liebert
2001 - 2007 Biotechnology and Bioengineering (1097-0290) Wiley (John Wiley & Sons)

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2018/09/15 - 2022/09/15 Coordinator of the mandatory module (5th year; branch: biomaterials) “Regenerative Medicine” in the Integrated Master of Biomedical Engineering Universidade de Coimbra, Portugal
2012/05/02 - 2022/05/02 Co-coordinator of the “Advanced Therapies” educational module (a 1 week-module per year) at the Experimental Biology and Biomedicine Program (2012- present) Universidade de Coimbra, Portugal

Tissue Engineering and Regenerative Medicine International Society, Estados Unidos
2006/05/02 - 2018/05/02 Co-coordinator of the “Cell and Tissue Engineering” educational module (a 2 week-module per year) at the MIT-Portugal Program (2006-2018) Universidade de Coimbra, Portugal

Entrevista (jornal / revista)

Descrição da atividade Jornal / Forum
2021/08/03 Contribution for the article entitled "Medicina anti-envelhecimento: mito, ciencia ou futuro?" about anti-ageing strategies in Noticias Magazine. Diario Noticias
2020/12/03 Press releases about the attraction of two European projects “COVIRNA” and “RESETageing” (Twinning project) in the most important National journals such as Publico and Diario de Noticias and advertised in the radio and TV. Publico
2020/08/17 Press article about a study published in Nature Communications entitled: "Vulnerability of progeroid smooth muscle cells to biomechanical forces is mediated by MMP13" Publico
2020/01/20 Article press about a study published in Angewandte Chemie entitled: “A light-activatable nanoparticle library for the controlled release of non-coding RNAs”. Publico
2018/10/18 Press article about a study published in ACS Nano entitled: “Modulation of angiogenic activity by light-activatable miRNA-loaded nanocarriers”. The article has been published in Diario de Noticias and advertised in the radio and TV. Diario de Noticias

Entrevista / Programa (rádio / tv)

Programa Tema
2017/08/04 - 2017/08/04 RTP1 ERA Chair project
2017/01/31 - 2017/01/31 Dias do Futuro, Antena 1 Premio Inovação Bluepharma
2014/01/13 - 2014/01/13 RTP1 Cientistas portugueses descobrem adesivo para reparar 'corações partidos'

Tutoria

Tópico Nome do aluno
2018/08 - Atual Cardiovascular ageing Ana Filipa Roque Branco
2018/03 - Atual Tiago Batista Abrantes Rondão
2018/02 - Atual Ines Maria Cunha Albino
2017/07 - Atual Nanomedicine Miguel Maria da Fonseca Miranda Ferreira Lino
2017/01 - Atual Nanomedicine Arnab Banerjee
2016/11 - Atual Cardiovascular ageing Patrícia Raquel Pinheiro Pitrez Pereira
2015/05 - Atual Remotely controlling gene editing in neural stem cells Susana Margarida Neto Simões
2014/08 - Atual Nanomedicine and ageing Luis Miguel Beicinha Branco Estronca
2014/04 - Atual Light-triggerable nanoparticles for non-coding RNA delivery Vitor Manuel dos Santos Francisco
2013/01 - Atual Cellular reprogramming by near infrared (NIR)-activatable nanoparticles containing transcription factors Sonia Luzia Claro de Pinho
2011/06 - Atual Differentiation of human pluripotent stem cells into endothelial cells using bioengineering tools Susana Carvalho Rosa
2017/08 - 2019/03 Nanomedicine Andreia Marques Ribeiro
2018/03 - 2018/09 Filipe Diogo Sousa Coelho
2017/06 - 2018/03 Antonio José da Silva Santinha
2017/09 - 2018/01 Mehrzad Zargarzadeh
2017/01 - 2017/12 Vanessa Pinto
2016/11 - 2017/11 Malwina Kotowicz
2016/04 - 2017/09 Bioengineering of mature cardiac constructs from human induced pluripotent stem cells (iPSC-derived) cardiomiocytes for drug screening and disease modeling Henrique Miguel Martiniano Vazão de Almeida
2015/05 - 2017/03 Stroke therapy based on exosomes Alessandra Arcoverde Cavalcanti Zonari
2017 - 2017 Supervision of short-term lab tranings for students enrolled in PhD programs Mariana Branco
2017 - 2017 Supervision of short-term lab tranings for students enrolled in PhD programs Rita Rodrigues Sá Ferreira
2016/05 - 2016/12 Nanomedicine Sandra Cristina Norte Pinto
2013/01 - 2016/08 Nanoparticles conjugated with photo-clevable linkers for the intracellular delivery of biomolecules Adrián Jiménez- Balsa
2012/09 - 2016/04 Sandra Pinto
2014/01 - 2016/01 Synthetic microparticles conjugated with VEGF165 improve the survival and function of endothelial progenitor cells via microRNA17 inhibition Sezin Aday
2014/03 - 2015/12 Enhanced diabetic wound healing by small extracellular vesicles controlled released by a light-triggerable hydrogel Renato Manuel Soares Cardoso
2015/01 - 2015/09 Tania Barata
2013/03 - 2015/06 Enhanced diabetic wound healing by small extracellular vesicles controlled released by a light-triggerable hydrogel Joana Rita Simões Correia
2012/12 - 2015/05 High-throughput identification of small molecules that affect human embryonic vascular development Helena Sofia Esmeraldo de Campos Vazão
2010/09 - 2015/05 José Miguel de Jesus Paiva
2014/01 - 2015/03 Diana Catarina Santos
2015 - 2015 Supervision of short-term lab tranings for students enrolled in PhD programs Claudia Fernandes
2014/04 - 2014/12 João Pedro Alves Lopes
2014/01 - 2014/09 João Santos
2014 - 2014 Supervision of short-term lab tranings for students enrolled in PhD programs Catarina Araujo Gomes Rebelo
2014 - 2014 Supervision of short-term lab tranings for students enrolled in PhD programs Bernardo Martins da Cunha Abecassis
2013/08 - 2013/12 Catarina Araujo Gomes Rebelo
2011/01 - 2013/12 Nanomedicine João Reina Maia e Silva
2010/03 - 2013/07 Nanomedicine Akhilesh Rai
2011/10 - 2013/05 Nanomedicine Marta Lima Evangelista
2010/06 - 2012/06 David José Roxo Botequim
2012 - 2012 Supervision of short-term lab tranings for students enrolled in PhD programs Inês Agapito Honório
2010/11 - 2011/11 Lysophosphatidic acid enhances survival of human CD34+ cells in ischemic conditions Isabel Maria Fidalgo Silva Carvalho
2009/01 - 2011/08 Nanomedicine Paula Sofia Sarrico Lacerda
2011/01 - 2011/07 Supervision of short-term lab tranings for students enrolled in PhD programs Leonardo Ricotti
2011 - 2011 Supervision of short-term lab tranings for students enrolled in PhD programs Patrícia Raquel Pinheiro Pitrez Pereira
2007/11 - 2010/11 Improved Survival, Vascular Differentiation and Wound Healing Potential of Stem Cells Co-cultured with Endothelial Cells Dora Cristina dos Santos Pedroso
2010 - 2010 Supervision of short-term lab tranings for students enrolled in PhD programs Carlos Samuel Marques Boto
2009 - 2009 Supervision of short-term lab tranings for students enrolled in PhD programs Maria Nunes Pereira
2009 - 2009 Supervision of short-term lab tranings for students enrolled in PhD programs Sezin Aday
2008 - 2008 Supervision of short-term lab tranings for students enrolled in PhD programs David Fernandes Braga Malta
Distinções

Prémio

2020 Best poster award, XIII Spanish-Portuguese Conference on Controlled Drug Delivery, Santiago de Compostela, 2020
2018 Best poster award, EMBO advanced course in extracellular vesicles, Heidelberg, Germany, April 2018
2017 Premio de Boas Práticas de Envelhecimento Ativo e Saudável na Região Centro: Conhecimento
Comissão de Coordenação e Desenvolvimento Regional do Centro, Portugal
2017 Best poster award, Sociedade Portuguesa de Células Estaminais e Terapias Celulares, Covilhã, Portugal, October 2017
2017 Best poster award, 6th China-Europe Symposium on Biomaterials in Regenerative Medicine (CESB2017), May 21-24, 2017, Porto
2017 Best poster award, V Jornadas de Química e Bioquímica, UBI, May 3-4, 2017, Covilhã
2016 ERA-CHAIR award, project: "Enhancing research in ageing at the university of Coimbra”
European Commission Sixth Framework Programme, Bélgica
2016 Bluepharma innovation award
Bluepharma, Portugal
2016 BIG innovation award, project “NoMicro”, Lisbon, July 2016
2016 World biomaterials congress travel award, for the abstract entitled "¿Prolonged intracellular accumulation of light-inducible nanoparticles in leukemia cells allows their remote activation" (Emanuel Quartin)
2015 FCT Investigator award (“advanced grant”)
Fundação para a Ciência e a Tecnologia, Portugal
2015 Medal of Honor L´Oreal Portugal for Women in Science (11th edition)(Raquel Ferreira)
2015 Forbes Magazine as “30 under 30” in Healthcare (Maria Pereira)
2014 Bristol Cardiovascular Early career research event, to the abstract "VEGF-bound beads modulate endothelial cell survival and microRNA expression" (Sezin Aday)
2014 MIT Technology Review¿s Annual Innovators under 35 (Maria Pereira)
2013 FCT Investigator award (“development grant”)
Fundação para a Ciência e a Tecnologia, Portugal
2013 Best poster award, Dresden School on Functional Nanomaterials (Dresden, October 2013). Poster entitled: “Light-activatable polymeric nanoparticles for intracellular delivery in cancer stem cells”. (Carlos Boto)
2013 Pulido Valente Ciencia 2013 prize (Tiago Santos)
2013 Best poster award
2013 Best oral communication, Sociedade Portuguesa de Células Estaminais e Terapias Celulares for the oral communication: "A stable and reproducible human blood-brain barrier model derived from stem cells" (Sezin Aday)
2012 European Research Council- Starting Independent Researcher Grant (StG, Grant nº 307384)
2012 Science, Engineering and Technology (SET) award, Silver prize in the Biological Sciences section (UK, 2012) attributed to Renata Gomes with the work entitled: “Nanoparticles for simultaneous MRI tracking and microRNA delivery"
2011 Science communication award, Mending Broken Hearts award (British Heart Foundation) (Renata Gomes)
2011 Best oral communication, 6th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies, Biocant, 28 e 29 de Abril, 2011 (Tiago Santos)
2010 Best poster award, TNT Conference- Trends in nanotechnology, Braga, 2010 (Cristiana Paulo)
2010 Best oral communication, 5th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies, Caldas das Taipas, May 2010 (Francisca Eiriz)
2008 Crioestaminal Prize
2005 First Prize, Current Progress in Tissue Engineering Conference (MIT, Boston, Massachusetts, USA) (Jeffrey Karp)
2005 First Prize, MIT Chemical Engineering Poster Competition (Boston, Massachusetts, USA) (Jeffrey Karp)

Outra distinção

2012 Member of the Jury of Pulido Valente Ciencia 2012 prize