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Isaura Martins. Completed the Mestrado integrado in Bioquímica in 2010/07/16 by Universidade de Coimbra, Licenciatura in Bioquímica in 2009/09/01 by Universidade de Coimbra and Doctor of Philosophy in PhD in Neuroscience in 2015/06/10 by The University of Manchester School of Biological Sciences. Is Collaboration with Prof. Phillip Popovich in The Ohio State University College of Medicine, Collaboration with Prof. Elizabeth Bradbury in Wolfson Center for Age-related Diseases, King´s College of London , Principal Investigator in Universidade Católica Portuguesa Faculdade de Medicina and Lecturer in Universidade Católica Portuguesa. Published 11 articles in journals. Has 4 patent(s) registered. Organized 4 event(s). Participated in 13 event(s). Co-supervised 2 PhD thesis(es). Supervised 3 MSc dissertation(s) e co-supervised 1. Has received 11 awards and/or honors. Participates and/or participated as PhD Student Fellow in 1 project(s), Post-doc in 4 project(s), Post-doc Fellow in 1 project(s) and Principal investigator in 3 project(s). Works in the area(s) of Medical and Health Sciences. In his curriculum Ciência Vitae the most frequent terms in the context of scientific, technological and artistic-cultural output are: Lesão da espinal medula, ; Spinal Cord; Spinal Cord Injury; Neurorepair; Behaviour; Alzheimer´s disease; Obesity; High-fat diet; Blood-brain barrier; Periphery; Memory; Regeneration ; Senescence; Senescent Cells; Endothelial cells; Spinal cord Injury; Endothelial; Genes; Zebrafish; Mouse; Endothelial Cells; Animal Behaviour; Animals; Cell Differentiation; Ependyma; Mammals; Mice; Neural Stem Cells; Neuroglia; Developmental Biology; Cell Biology; General Biochemistry, Genetics and Molecular Biology; Molecular Biology; Neurosciences; FOS: Clinical medicine; Model organisms; Synthetic Biology; Imaging; Tumour Biology; Signalling & Oncogenes; Gene Expression; Genetics & Genomics; Genome Integrity & Repair; Human Biology & Physiology; Microfabrication & Bioengineering; Stem Cells; Chemical Biology & High Throughput; Infectious Disease; Ecology,Evolution & Ethology; Immunology; Computational & Systems Biology; Regenerative Medicine; Biologia Molecular e Celular; Desenvolvimento; Envelhecimento e Cancro; Infeção e Imunidade; Neurociências e Comportamento; Biologia Celular e do Desenvolvimento; Imunologia; Infecção; Neurociências; .
Identificação

Identificação pessoal

Nome completo
Isaura Martins

Nomes de citação

  • Martins, Isaura

Identificadores de autor

Ciência ID
5D14-4AD4-F366
ORCID iD
0000-0002-1329-7769

Endereços de correio eletrónico

  • ismartins@ucp.pt (Profissional)

Websites

Domínios de atuação

  • Ciências Médicas e da Saúde

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Inglês Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2)
Formação
Grau Classificação
2020 - 2020
Concluído
Trends in CNS Regenerative Medicine (Outros)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2018/09 - 2018/09
Concluído
Advanced Neuroscience Courses (Outros)
Especialização em Spinal Cord Injury
Neuroscience School of Advanced Studies, Itália
2017 - 2017
Concluído
Spinal Cord Injury Training Program (Outros)
The Ohio State University, Estados Unidos
2011/04/01 - 2015/06/10
Concluído
PhD in Neuroscience (Doctor of Philosophy)
Especialização em Neuroscience
The University of Manchester School of Biological Sciences, Reino Unido
"The effect of a high-fat diet in health and in an animal model of Alzheimer's disease: a gender comparison study" (TESE/DISSERTAÇÃO)
Minor corrections
2008/09/01 - 2010/07/16
Concluído
Bioquímica (Mestrado integrado)
Especialização em Neuroscience
Universidade de Coimbra, Portugal
"Neuroprotection by leptin and ghrelin against amyloid-beta toxicity in hippocampal neurons. Relevance for therapeutic intervention in Alzheimer's disease. " (TESE/DISSERTAÇÃO)
17
2005/09/01 - 2009/09/01
Concluído
Bioquímica (Licenciatura)
Especialização em Bioquímica
Universidade de Coimbra, Portugal
"The role of mitochondrion – the importance of Rh0 cells in Alzheimer's disease." (TESE/DISSERTAÇÃO)
14
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento
Empregador
2024/12/10 - Atual Investigador principal (carreira) (Investigação) Universidade Católica Portuguesa Faculdade de Medicina, Portugal
Universidade Católica Portuguesa Centro de Investigação Interdisciplinar em Saúde, Portugal
2024/10/12 - 2025/03/31 Investigador visitante (Investigação) Gulbenkian Institute for Molecular Medicine, Portugal
Instituto de Medicina Molecular, Portugal
2023/06/01 - 2024/10/05 Investigador Contratado (Investigação) Instituto de Medicina Molecular, Portugal
2015/12/03 - 2023/05/31 Pós-doutorado (Investigação) Instituto de Medicina Molecular, Portugal
2016/11/01 - 2016/12/01 Investigador visitante (Investigação) Deutsches Krebsforschungszentrum, Alemanha
Deutsches Krebsforschungszentrum, Alemanha

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento
Empregador
2025/01/01 - Atual Leitor (Docente Universitário) Universidade Católica Portuguesa, Portugal

Outros

Categoria Profissional
Instituição de acolhimento
Empregador
2022/01 - Atual Collaboration with Prof. Phillip Popovich The Ohio State University College of Medicine, Estados Unidos
2018/04 - 2020/01/01 Colaboration with Prof Caetano Reis e Sousa Francis Crick Institute, Reino Unido
Francis Crick Institute, Reino Unido
2017/05/07 - 2017/05/19 Student of the Craig Nelson Foundation-funded Spinal Cord Injury Research Training Program The Ohio State University, Estados Unidos
Projetos

Bolsa

Designação Financiadores
2023/01/15 - Atual Endothelial CD9 as a new anti-inflammatory target to promote spinal cord repair
2022.05669.PTDC
Investigador responsável
Instituto de Medicina Molecular, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2024/07/01 - 2026/06/30 MYLIP_PRINT: exploiting the role of MYLIP positive pericytes in SCI
WFL-PT-19/24
Investigador responsável
Wings for Life Spinal Cord Research Foundation, Reino Unido
Em curso
2023/09/01 - 2025/03/31 CD9/MYLIP_AGEnts: Targeting pericytes to prevent neuroinflammation and promote barrier integrity after spinal cord injury
NA
Investigador responsável
Morton Cure Paralysis Fund Minnesota, Estados Unidos
Morton Cure Paralysis Fund Minnesota
Em curso
2020/12/01 - 2023/12/31 Senescent cells and their secretory phenotype: novel targets for spinal cord repair
MC-36-2020
Investigador Pós-doutorado
Instituto de Medicina Molecular, Portugal
Santa Casa da Misericórdia de Lisboa
Em curso
2017/04/01 - 2023/05/31 Angiocrine factors as modulators of spinal cord regeneration
SFRH/BPD/118051/2016
Bolseiro de Pós-Doutoramento
Instituto de Medicina Molecular, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2019/10/01 - 2022/09/30 Targeting induced-senescent cells: a novel approach to promote spinal cord regeneration in mamals
HR18-00187
Investigador Pós-doutorado
Instituto de Medicina Molecular, Portugal
Caixa d'Estalvis i Pensions de Barcelona
Em curso
2018/10/01 - 2021/09/30 Modulation of vascular repair during spinal cord regeneration
PTDC/BIA-BID/28572/2017
Investigador Pós-doutorado
Instituto de Medicina Molecular, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2018/10/01 - 2021/09/30 The function of induced-senescent cells in spinal cord regeneration
PTDC/MED-NEU/30428/2017
Investigador Pós-doutorado
Instituto de Medicina Molecular, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2011/04/01 - 2015/03/31 Effects of a high-fat diet in health and in Alzheimer´s disease: a gender comparison study
SFRH/BD/73041/2010
Bolseiro de Doutoramento
The University of Manchester, Reino Unido
Fundação para a Ciência e a Tecnologia
Concluído

Projeto

Designação Financiadores
2021/01/01 - 2025/12/31 Instituto de Medicina Molecular João Lobo Antunes
LA/P/0082/2020
Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2019/01/01 - 2019/12/31 Instituto de Medicina Molecular - IMM
UID/BIM/50005/2019
Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
Produções

Publicações

Artigo em conferência
  1. Martins, Isaura; Allan, Stuart; Lawrence, Catherine. "THE EFFECT OF RESVERATROL SUPPLEMENTATION ON THE EFFECTS OF A HIGH-FAT DIET IN A 3XTGAD FEMALE MOUSE MODEL OF ALZHEIMER'S DISEASE". Trabalho apresentado em Alzheimer's Association International Conference, Copenhaga, 2014.
    10.1016/j.jalz.2014.05.648
  2. Martins, Isaura; Knight, Elysse; Allan, Stuart; Lawrence, Catherine. "Effects of a high-fat diet on the cerebrovasculature and neuroinflammation in an experimental model of Alzheimer's disease". Trabalho apresentado em Alzheimer´s Association International Conference, Vancouver, 2012.
    10.1016/j.jalz.2012.05.1263
Artigo em revista
  1. Martins, Isaura; Neves-Silva, Dalila; Ascensão-Ferreira, Mariana; Dias, Ana Filipa; Ribeiro, Daniel; Isidro, Ana Filipa; Quitéria, Raquel; et al. Autor correspondente: Martins, Isaura. "Mouse Spinal Cord Vascular Transcriptome Analysis Identifies CD9 and MYLIP as Injury-Induced Players". International Journal of Molecular Sciences 24 7 (2023): 6433. http://dx.doi.org/10.3390/ijms24076433.
    10.3390/ijms24076433
  2. Isidro, Ana Filipa; Medeiros, Alexandra M.; Martins, Isaura; Neves-Silva, Dalila; Saúde, Leonor; Mendes, César S.. "Using the MouseWalker to Quantify Locomotor Dysfunction in a Mouse Model of Spinal Cord Injury". Journal of Visualized Experiments 193 (2023): http://dx.doi.org/10.3791/65207.
    10.3791/65207
  3. Bruno Frederico; Martins, Isaura; Diana Chapela; Francesca Gasparrini; Probir Chakravarty; Tobias Ackels; Cécile Piot; et al. "DNGR-1-tracing marks an ependymal cell subset with damage-responsive neural stem cell potential.". Developmental cell 57 (2022):
    Acesso aberto • 10.1016/j.devcel.2022.07.012
  4. Paramos-de-Carvalho, Diogo*; Martins, Isaura*; Cristóvão, Ana Margarida; Dias, Ana Filipa; Neves-Silva, Dalila; Pereira, Telmo; Chapela, Diana; et al. "Targeting senescent cells improves functional recovery after spinal cord injury". *shared first-author. Cell Reports 36 1 (2021): 109334. http://dx.doi.org/10.1016/j.celrep.2021.109334.
    10.1016/j.celrep.2021.109334
  5. Paramos-de-Carvalho, Diogo*; Martins, Isaura (5D14-4AD4-F366)*; Cristovão, Ana Margarida; Dias, Ana Filipa; Neves-Silva, Dalila; Pereira, Telmo; Chapela, Diana; et al. "Depletion of senescent cells improves functional recovery after spinal cord injury". * These two authors contributed equally to this work, bioRxiv (2020): https://www.biorxiv.org/content/10.1101/2020.10.28.358762v1.full.
    10.1101/2020.10.28.358762
  6. Chapela, Diana; Sousa, Sara; Martins, Isaura; Cristóvão, Ana Margarida; Pinto, Patrícia; Corte-Real, Sofia; Saúde, Leonor. "A zebrafish drug screening platform boosts the discovery of novel therapeutics for spinal cord injury in mammals". Scientific Reports 9 1 (2019): http://dx.doi.org/10.1038/s41598-019-47006-w.
    10.1038/s41598-019-47006-w
  7. Martins, Isaura V.A.; Rivers-Auty, Jack; Allan, Stuart M.; Lawrence, Catherine B.. "Mitochondrial Abnormalities and Synaptic Loss Underlie Memory Deficits Seen in Mouse Models of Obesity and Alzheimer’s Disease". Journal of Alzheimer's Disease 55 3 (2016): 915-932. http://dx.doi.org/10.3233/jad-160640.
    10.3233/jad-160640
  8. Knight, Elysse M.; Martins, Isaura V.A.; Gümüsgöz, Sarah; Allan, Stuart M.; Lawrence, Catherine B.. "High-fat diet-induced memory impairment in triple-transgenic Alzheimer's disease (3xTgAD) mice is independent of changes in amyloid and tau pathology". Neurobiology of Aging 35 8 (2014): 1821-1832. http://dx.doi.org/10.1016/j.neurobiolaging.2014.02.010.
    10.1016/j.neurobiolaging.2014.02.010
  9. Gomes, S.; Martins, I.; Fonseca, A. C. R. G.; Oliveira, C. R.; Resende, R.; Pereira, C. M. F.. "Protective Effect of Leptin and Ghrelin against Toxicity Induced by Amyloid-ß Oligomers in a Hypothalamic cell Line". Journal of Neuroendocrinology 26 3 (2014): 176-185. http://dx.doi.org/10.1111/jne.12138.
    10.1111/jne.12138
  10. Martins, I.; Gomes, S.; Costa, R.O.; Otvos, L.; Oliveira, C.R.; Resende, R.; Pereira, C.M.F.. "Leptin and ghrelin prevent hippocampal dysfunction induced by Aß oligomers". Neuroscience 241 (2013): 41-51. http://dx.doi.org/10.1016/j.neuroscience.2013.02.062.
    10.1016/j.neuroscience.2013.02.062
  11. Costa, Rui O.; Ferreiro, Elisabete; Martins, Isaura; Santana, Isabel; Cardoso, Sandra M.; Oliveira, Catarina R.; Pereira, Cláudia M.F.. "Amyloid ß-induced ER stress is enhanced under mitochondrial dysfunction conditions". Neurobiology of Aging 33 4 (2012): 824.e5-824.e16. http://dx.doi.org/10.1016/j.neurobiolaging.2011.04.011.
    10.1016/j.neurobiolaging.2011.04.011
Poster em conferência
  1. Neves-Silva, Dalila; Isa Fernandes Mota; Madalena Pires; Leonor Saúde; Martins, Isaura. Autor correspondente: Martins, Isaura. "IDOLizing pericytes regulatorsof cardiometabolic effects after spinal cord inury". Trabalho apresentado em XIX Meeting Portuguese Society for Neurosciences, 2025.
  2. Ribeiro, Daniel; Isidro, Ana Filipa; Martins, Isaura; Leonor Saúde; Joao Pedro de Magalhaes. "Identifying injury-induced cellular senescence in the spinal cord by single cell RNA-seq". Trabalho apresentado em 4th International Meeting of the Portuguese Research Network on Spinal Cord Injury, 2024.
  3. Ribeiro, Daniel; Isidro, Ana Filipa; Martins, Isaura; Magalhaes, Joao; Saúde, Leonor. "Single cell analysis of the spinal cord reveals a persistent, injury-induced neuronal cell state". Trabalho apresentado em 13th EMBO Young Scientists¿ Forum, 2023.
  4. Martins, Isaura; Neves-Silva, Dalila; Ascensão-Ferreira, Mariana; Ribeiro, Daniel; Isidro, Ana Filipa; Dias, Ana Filipa; Quitéria, Raquel; et al. Autor correspondente: Martins, Isaura. "CD9 and MYLIP as two new vascular players in spinal cord injury". Trabalho apresentado em 13th EMBO Young Scientists¿ Forum, 2023.
  5. Neves-Silva, Dalila; Martins, Isaura; Rebocho da Costa, Mariana; Quitéria, Raquel; Saúde, Leonor. "The right time to "scar"". Trabalho apresentado em XVI CAML · VI NeurULisboa PhD Students Meeting, 2023.
  6. Isidro, Ana Filipa; Medeiros, Alexandra M.; Martins, Isaura; Neves-Silva, Dalila; Saúde, Leonor; Mendes, César S.. Autor correspondente: Mendes, César S.. "Taking a walk on the acrylic slide: Using the MouseWalker to quantify locomotor dysfunction in a mouse model of spinal cord injury". Trabalho apresentado em XVI CAML / VI NeurULisboa PhD Students Meeting, 2023.
  7. Ribeiro, Daniel; Isidro, Ana Filipa; Martins, Isaura; Saúde, Leonor. "A Single-cell Atlas of the Mouse Spinal Cord during the Acute and Chronic Injury Response Phases". Trabalho apresentado em 2nd International Meeting of the Portuguese Research Network on Spinal Cord Injury, 2022.
  8. Isidro, Ana Filipa; Ribeiro, Daniel; Martins, Isaura; Saúde, Leonor. Autor correspondente: Saúde, Leonor. "The role of induced senescent cells after spinal cord injury". Trabalho apresentado em XV CAML/ V NeurULisboa Annual PhD Students Meeting, 2022.
  9. Neves-Silva, Dalila; Martins, Isaura. "Mimicking the Zebrafish Extracellular Matrix Profile in Mammals to Promote Spinal Cord Repair". 2021.
  10. "Targeting senescent cells improves functional recovery after spinal cord injury". 2021.
  11. Isidro, Ana Filipa; Ribeiro, Daniel; Martins, Isaura; Saúde, Leonor. Autor correspondente: Saúde, Leonor. "The role of induced senescent cells on spinal cord injury". Trabalho apresentado em XIV CAML . IV NeurULisboa Annual PhD Students Virtual Meeting, 2021.
  12. Martins, Isaura. "The Endothelial Cells Transcriptome after Spinal Cord Injury A tale of two opposite models: Zebrafish vs Mouse". Trabalho apresentado em 21st Spinal Research Network Meeting London, 2019.
  13. Martins, Isaura. "Angiocrine Factors as Modulatores of Spinal Cord Regeneration". Trabalho apresentado em Lesões Vertebro Medulares- LVM Meeting 2016, 2016.
  14. Martins, Isaura. "The effect of resveratrol supplementation on the effects of a high-fat diet in 3xTgAD female mouse model of Alzheimer diseases". Trabalho apresentado em Alzheimer's Association International Conference 2014, 2014.
  15. Martins, Isaura. "Comparison of the effects of a high-fat diet (HFD) in male and female Alzheimer's disease mice". Trabalho apresentado em Alzheimer's Research UK Conference 2014, 2014.
  16. Martins, Isaura. "The Effect of High-Fat Diet in the Triple Transgenic Mouse Model of Alzheimer's Disease". Trabalho apresentado em Alzheimer's Research UK Conference 2013, 2013.
  17. Martins, Isaura. "Effects of a High-Fat Diet on the Cerebrovasculature and Neuroinflammation in an Experimental Model of Alzheimer's Disease". Trabalho apresentado em Alzheimer's Association International Conference 2012, 2012.
  18. Martins, Isaura. "The effect of high-fat diet on neurovascular dysfunction in a animal model of Alzheimer's disease (3xTgAD)". Trabalho apresentado em 7th International Symposium on Neuroprotection and Neurorepair 2012, 2012.
  19. Martins, Isaura; Gomes, Sílvia; Costa, Rui; Resende, Rosa; Oliveira, Catarina R; Pereira, Cláudia Fragão. "Ghrelin and leptin protect hippocampal neurons against Aß-induced toxicity. Relevance for therapeutic intervention in Alzheimer’s disease.". Trabalho apresentado em XVII National Congress of the Portuguese Biochemical Society, 2010.
  20. Martins, Isaura. "Effect of leptin and ghrelin in hippocampal neurons against Alzheimer´s disease neurotoxins – amyloid-beta peptide". Trabalho apresentado em XVII National Congress of Biochemistry, 2010.
  21. Martins, Isaura. "Ghrelin and leptin protect hippocampal neurons and hypothalamic cells against Aß-induced toxicity. Relevance for therapeutic intervention in Alzheimer´s disease". Trabalho apresentado em Second National Meeting on Medicinal Chemistry, 2010.
  22. Martins, Isaura. "Leptin and Ghrelin protect against Aß-induced toxicity in hippocampal and hypothalamic neurons". Trabalho apresentado em Network of European Neuroscience Institutes, Final Annual Network Meeting, 2010.
Resumo em conferência
  1. Isidro, Ana Filipa; Domingos, Inês; Ribeiro, Daniel; Neves-Silva, Dalila; Quitéria, Raquel; Martins, Isaura; Saúde, Leonor. Autor correspondente: Saúde, Leonor. "The role of p16+ cells on spinal cord neuroprotection and repair after an injury". Trabalho apresentado em 4th Meeting Spinal Cord Injury PT Researchers, Lisboa, 2024.
Tese / Dissertação
  1. Martins, Isaura. "Effects of a high-fat diet in health and in Alzheimer´s disease: a gender comparison study". Doutoramento, The University of Manchester, 2015.
  2. Martins, Isaura. "Neuroprotection by leptin and ghrelin against amyloid-beta toxicity in hippocampal neurons. Relevance for therapeutic intervention in Alzheimer's disease". Mestrado, Universidade de Coimbra Faculdade de Ciencias e Tecnologia, 2010.
  3. Martins, Isaura. "The role of mitochondrion – the importance of Rh0 cells in Alzheimer's disease.". Licenciatura, Universidade de Coimbra Faculdade de Ciencias e Tecnologia, 2009.

Propriedade Intelectual

Patente
  1. Martins, Isaura; Saúde, Leonor; Neves-Silva, Dalila. 2023. "“Treatmenet of Spinal Injury”". Portugal.
    Pendente
  2. Paramos-de-Carvalho, Diogo; Martins, Isaura; Jacinto, António; Saúde, Leonor. 2020. "The use of senolytic compounds in the treatment of spinal cord injury". Portugal.
    Concedida/Emitida
  3. Paramos-de-Carvalho, Diogo; Martins, Isaura; Jacinto, António; Saúde, Leonor. 2020. "Treatment of spinal cord injury (PCT/EP2020/07576)". Portugal.
    Concedida/Emitida
  4. Chapela, Diana; Côrte-Real, Sofia; Saúde, Leonor; Martins, Isaura; Sousa, Patrícia Filipa Saraiva de. 2020. "Eletriptan Hydrobromide for treatment of spinal cord injury and improvement of locomotor function". Portugal.
    Pendente
Pedido provisório de patente
  1. 2023. "Treatment of Spinal Injury".
    Protegido
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2025/04/10 Neurovascular interactions in spinal cord injury CMS Seminars
Católica Medical School
2023/10/27 Vascular therapeutic approaches to improve spinal cord repair: CD9 and MYLIP as two new vascular injury-induced players - Keynote Speaker Medical Technologies in Spinal Cord Injury
Universidade de Aveiro (Aveiro, Portugal)
2023/03/03 Mouse spinal cord vascular transcriptome analysis identifies CD9 and MYLIP as injury-induced players Building Bridges in Biology Symposium
Instituto Ciência Gulbenkian - IGC (Lisboa, Portugal)
2022/06/03 Endothelial cells as modulators of spinal cord regeneration: a tale of two models, zebrafish and mouse
NOVA Medical School
2022/05/05 Targeting Senescent Cells Improves Functional Recovery After Spinal Cord Injury
(Lisboa, Portugal)
2022/04/06 Targeting Senescent Cells Improves Functional Recovery After Spinal Cord Injury
Universidade de Coimbra (Coimbra, Portugal)
2022/03/19 Targeting Senescent Cells Improves Functional Recovery After Spinal Cord Injury Central Nervous System Injury and Repair
Gordon Research Seminar (GRS) (Oxnard , Estados Unidos)
2021/12/15 Improving spinal cord repair: from targeting senescence to endothelial cells and beyond UC-Biotech Seminars
UC-Biotech (Coimbra, Portugal)
2020/12/11 Senescent cells as a new players in Spinal Cord Injury. A tale of two opposite models: Zebrafish vs Mouse Development in Action (DiA) Meeting
Instituto de Investigação e Inovação em Saúde (i3S) - Universidade do Porto (Porto, Portugal)
2020/11/02 Senescent cells as a new players in Spinal Cord Injury. A tale of two opposite models: Zebrafish vs Mouse International Online Spinal Cord Injury Research Seminars (i-OSCIRS)
(Estados Unidos)
2019/05 The Endothelial Cells Transcriptome after Spinal Cord Injury. A tale of two opposite models: Zebrafish vs Mouse PostDoc Day Instituto de Medicina Molecular
(Lisboa, Portugal)
2018/11 Endothelial cells and spinal cord injury Lisbon Area PostDoctoral Meeting 2018
(Lisboa, Portugal)
2017/05 Angiocrine factors as potential modulators of spinal cord regeneration Lesões vertebro medulares (LVM) Meeting
(Porto, Portugal)
2014/07 The effect of a high-fat diet on an animal model of Alzheimer's disease Neuroscience Symposium
University of Manchester (Manchester, Reino Unido)
2014/05 Resveratrol supplementation on the effects of a high-fat diet in female 3xTgAD mice PhD Conference 2014 – University of Manchester
University of Manchester (Manchester, Reino Unido)
2014/03 Comparison of the effects of a high-fat diet (HFD) in male and female Alzheimer's disease mice PhD day Alzheimer's Research UK Conference 2014
Alzheimer´s Research UK (Oxford, Reino Unido)
2013/06 The role of the cerebrovasculature in the detrimental effect of a high-fat diet on Alzheimer's disease Alzheimer's Research Trust Manchester Meeting
Alzheimer´s Research Trust (Manchester, Reino Unido)
2013/05 The effect of high fat diet in triple transgenic mouse model of Alzheimer's disease PhD Conference 2013 – University of Manchester
University of Manchester (Manchester, Reino Unido)
2012/02 Effects of a high-fat diet on the cerebrovasculature and neuroinflammation in an experimental model of Alzheimer´s disease Alzheimer's Research Trust Manchester Meeting
Alzheimer´s Research Trust (Manchester, Reino Unido)
2010/10 Ghrelin and leptin signal pathways in the brain: towards novel disease-modifying drugs for Alzheimer's disease.” Angelini University Award 09/10
Angelini (Lisboa, Portugal)
2010/06 Neuroprotection by leptin and ghrelin against amyloid-beta toxicity in hippocampal neurons. Relevance for therapeutic intervention in Alzheimer's disease 24ª Reunião do Grupo de Estudos de Envelhecimento Cerebral e Demência
(Tomar, Portugal)

Orientação

Título / Tema
Papel desempenhado
Curso (Tipo)
Instituição / Organização
2020/09/01 - Atual The role of induced-senescent cells in spinal cord injury
Coorientador
Instituto de Medicina Molecular, Portugal
2024/09/01 - 2025/08/31 Uncovering the role of MYLIP-expressing pericytes as new regulators of neuroinflammation and blood spinal cord barrier integrity after spinal cord injury
Orientador de Madalena Pires
Master Biomedical Research (Mestrado)
Instituto de Medicina Molecular, Portugal
2019/09/01 - 2024/07/30 Using the regenerative potential of zebrafish extracellular matrix to promote spinal cord repair in mammals
Coorientador
Instituto de Medicina Molecular, Portugal
2021/10/05 - 2022/09/30 The senescent profile in peripheral organs after a spinal cord injury
Coorientador
Mestrado Integrado Medicina Veterinária (Mestrado)
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
2020/03/01 - 2020/04/30 The role of periphery in spinal cord injury
Orientador
Universidade do Algarve Departamento de Ciências Biomédicas e Medicina, Portugal
2018/07/01 - 2018/08/02 The Endothelial Cells Transcriptome after Spinal Cord Injury
Orientador
SCORE Research Exchange - Intercâmbios em Investigação Científica, da IFMSA (Outra)
Samarskij gosudarstvennyj medicinskij universitet, Rússia
2013/09 - 2014/09 Effect of High Fat Diet and Alzheimer's Disease on Peripheral Inflammation and Oxidative Stress: Potential of Resveratrol to Attenuate Peripheral Mechanisms and Cognition.
Orientador
Masters of Research in the Faculty of Life Sciences (Mestrado)
The University of Manchester, Reino Unido

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação)
Instituição / Organização
2024/09/16 - Atual Organization of the 4th Spinal Cord Injury Portuguese Meeting (2024/09/16)
Conferência (Membro da Comissão Organizadora)
Gulbenkian Institute for Molecular Medicine, Portugal
2021/12/03 - Atual "Rir para não chorar" - A round table to talk about mental health and the impact of the pandemics in the brain. This event took place in a coffee shop in Coimbra and joined one Neuroscientist (Dr. Catarina Gomes), one Psychiatrist (Dr. Miguel Bajouco) and two comedians (Rita Leão e João Moreira). (2021/12/03 - 2021/12/03)
Mesa-redonda (Membro da Comissão Organizadora)
Fala-me Neuro, Portugal
2020/11/01 - 2021/12/31 "Fala-me Neuro" is a portuguese science communication project developed to be accessible to everyone who wants to know more about Neurosciences, from credible sources in a simple and lay way in portuguese. It was developed and organised by a group of young neuroscientists from all over Portugal and counts with the support of Sociedade Portuguesa de Neurociências (SPN). (2021/02/13)
Outro (Coorganizador)
Sociedade Portuguesa de Neurociências, Portugal
2009/04/18 - 2009/04/18 Commemoration of 30th anniversary of the Biochemistry course in Portugal (2009/04/18 - 2009/04/19)
Simpósio (Membro da Comissão Organizadora)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal

Participação em evento

Descrição da atividade
Tipo de evento
Nome do evento
Instituição / Organização
2021/11/24 - Atual Invitation to talk at Escola nº1 de Rio de Mouro for the "Dia do Cientista" event.
Outro
Dia do Cientista
Escola Nº1 de Rio de Mouro, Portugal
2020/11/29 - Atual Speaker for "Dia do Cientista 202" in Pavilhão do Conhecimento - Ciência Viva
Outro
Dia do Cientista
Ciência Viva, Portugal
2020/11/27 - Atual Part of the members of the virtual round table for "Noite dos Investigadores 2020"
Mesa-redonda
Noite dos Investigadores Virtual 2020
Instituto de Medicina Molecular, Portugal
2017/06 - Atual Speaker at the 17º PubhD in Lisbon about spinal cord regeneration (https://pubhdlisboa.wordpress.com/2017/04/30/17o-pubhd-de-lisboa-em-revista/)
Mesa-redonda
17ºPubhD Lisbon
2023/05/22 - 2023/05/24 Invited speaker for “Com Pés e Cabeça”, a public engagement event that talks about research in the fields of medicine, human biology and health.
Festival
Pint of Science Festival 2023
Pint of Science , Portugal
2020/11/10 - 2020/11/19 Workshop Neuro-omics, including the bases and knowledge of RNAsequencing and proteomics design and analysis
Oficina (workshop)
Stanford Neuro-Omics 2020 Virtual Workshop
Stanford Neurosciences Institute, Estados Unidos
2020/03/02 - 2020/03/06 Advanced Course - Recent Trends in CNS Regenerative Medicine
Outro
Advanced Course - Recent Trends in CNS Regenerative Medicine
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2018/09/08 - 2018/09/15 Spinal Cord Injury Course from Neuroscience School of Advanced Studies (NSAS) in Venice, Italy Neuroscience School of Advanced Studies (NSAS) in Venice
Neuroscience School of Advanced Studies, Itália
2017/05/07 - 2017/05/19 The Craig Nelson Foundation-funded Spinal Cord Injury Research Training Program. The top research training program in the field of spinal cord injury where during two weeks only a dozen of participants are selected to learn the biological and molecular basis of spinal cord injury together with training in surgery procedures and animal models and techniques from histology to electrophisiology.
Oficina (workshop)
The Craig Nelson Foundation-funded Spinal Cord Injury Research Training Program
The Ohio State University, Estados Unidos
2016/06/20 - 2016/06/22 EMBO Leadership and Management Skills Course
Oficina (workshop)
Leadership and Management Skills Course
HFP Consulting, Alemanha
2015/09 - 2016 Participating in Noite dos Investigadores (https://noitedosinvestigadores.org/)
Outro
Noite dos Investigadores 2015, 2016
Instituto de Medicina Molecular, Portugal
2011/06/01 - 2015/01/04 Several Public Engagement Activities
Outro
Brain Bus, Brain Awareness Week
The University of Manchester Faculty of Biology Medicine and Health, Reino Unido
2014/05/01 - 2014/11/30 Volunteer at Central Manchester University Hospital,Manchester, United Kingdom
Outro
Volunteer

Júri de grau académico

Tema
Tipo de participação
Nome do candidato (Tipo de grau)
Instituição / Organização
2025/01/30 Impact and Transcriptomic Analysis of the Effect of the Secretome of Adipose Tissue derived Stem Cells in an in vitro Model of Spinal Cord Injury
Arguente principal
Ana Teresa Palha Sousa (Mestrado)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2025/01/28 Compound Library Screening for Neural Repair: Finding New Drugs for Old Problems
Arguente principal
Luís Carlos Sousa Fernandes (Mestrado)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2022/12/07 The effects of Metabolic Reprogramming during Zebrafish Tissue Regeneration
Arguente
Jorge Miguel Ramalho Borbinha (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal

Arbitragem científica em conferência

Nome da conferência Local da conferência
2024/09/16 - Atual 4th Spinal Cord Injury Portuguese Meeting

Arbitragem científica em revista

Nome da revista (ISSN) Editora
2018/02/01 - Atual Journal de Investigação Médica (JIM) Ponteditora

Consultoria / Parecer

Descrição da atividade Instituição / Organização
2021/04/01 - 2021/06/30 Consultant for science writing - provided assistance with researching and drafting resource pages pertaining to rare diseases/neurosciences. Haymarket Media Inc, Estados Unidos

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2025/03/11 - Atual Master in Biopharmaceutical Sciences - Physiopathology of Neuroinflammation Master in Biopharmaceutical Sciences - Physiopathology of Neuroinflammation (Mestrado) Universidade de Lisboa Faculdade de Farmácia, Portugal
2012/01/01 - 2014/09/01 Demonstrator at University of Manchester in practical classes and lectures (Bachelor) The University of Manchester Faculty of Biology Medicine and Health, Reino Unido

Entrevista (jornal / revista)

Descrição da atividade Jornal / Forum
2017/03/01 Sobre o papel da mulher na ciência e a pressão de cada uma seguir um caminho ditado. "Ser mulher, cientista ou chefe? Cada uma é como é." Diário de Notícias

Entrevista / Programa (rádio / tv)

Programa Tema
2025/04/27 - Atual Spinal Cast
2023/05/02 - 2023/05/02 O Futuro não está escrito - Rádio Movimento

Membro de associação

Nome da associação Tipo de participação
2024/11/01 - Atual ALBA
2023/09/01 - Atual EUROSPINE
2023/06/01 - Atual World Women in Neuroscience (WWN) Member and mentor
2021/12/03 - Atual Sociedade Portuguesa de Neurociências (SPN) Member
2016/02 - 2017/03 Postdoctoral Association of Instituto de Medicina Molecular (iMM) Member of the Postdoctoral Association of Instituto de Medicina Molecular (iMM), organised several postdoctoral activities such as Postdoc Day at iMM, Postdoc Retreat and a Gender Balance in Science Debate to promote awareness of women in science with several important scientists worldwide such as the 2013 Laureate UNESCO-L´Oreal “For Women in Science” Reiko Kuroda and the EMBO Director Maria Leptin (https://justnews.pt/noticias/instituto-de-medicina-molecular-acolhe-debate-sobre-a-igualdade-de-generos-na-ciencia#.XWUs5OhKg2w)
2012 - 2014 Understanding Animal Research UK (http://www.understandinganimalresearch.org.uk) Participating in school initiatives to share awareness regarding the use of animals in science.
2007/01/01 - 2009/12/06 Biochemistry Students Association, Coimbra Member (2007-2008) and Vice-President (2008-2009)

Membro de comissão

Descrição da atividade
Tipo de participação
Instituição / Organização
2021/02/13 - Atual "Fala-me Neuro" is a portuguese science communication project developed to be accessible to everyone who wants to know more about Neurosciences, from credible sources in a simple and lay way in portuguese. It was developed and organised by a group of young neuroscientists from all over Portugal and counts with the support of Sociedade Portuguesa de Neurociências (SPN).
Membro
Fala-me Neuro, Portugal

Revisão ad hoc de artigos em revista

Nome da revista (ISSN) Editora
2022/12/02 - 2023/02/10 Frontiers of Neuroscience

Tutoria

Tópico Nome do aluno
2025/01/01 - Atual World Women in Neuroscience Mentoring Program Maria Binu Jacob
Distinções

Prémio

2025 SPN effective member Travel Grant
Sociedade Portuguesa de Neurociências, Portugal
2025 DMM Conference Travel Grant CTG-DMM25021825
The Company of Biologists Ltd, Reino Unido
2023 Outstanding Developmental Biology Paper Award 2023
Sociedade Portuguesa de Biologia do Desenvolvimento, Portugal
2022 Lídia Silva Santos Postdoctoral Achievement Award
Instituto de Medicina Molecular, Portugal
2022 Best oral Communication Award - I International Meeting on the Brain Vasculature
Sociedade Portuguesa de Neurociências, Portugal
2021 Pfizer Basic Research Award
Pfizer Portugal, Portugal
2013 Prize for best oral presentation in Neurosciences at the PhD Conference 2013

Outra distinção

2022 Exploratory Research Projects Grant
Fundação para a Ciência e a Tecnologia, Portugal
2017 Sponsorship to attend SCITP 2017 Ohio State University
Craig H Neilsen Foundation, Estados Unidos
2016 Postdoc Fellowship Grant - SFRH/BPD/118051/2016
Fundação para a Ciência e a Tecnologia, Portugal
2014 Travel grant to attend Alzheimer´s Association International Conference 2014 in Copenhagen, Denmark
Guarantors Of Brain, Reino Unido
2013 Travel grant to attend Alzheimer´s Association International Conference 2013 in Vancouver, Canada
2010 PhD Fellowship Grant - SFRH/BD/73041/2010
Fundação para a Ciência e a Tecnologia, Portugal