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Isaura Martins. Completed the Mestrado integrado in Bioquímica in 2010/07/16 by Universidade de Coimbra, Licenciatura in Bioquímica in 2009/09/01 by Universidade de Coimbra and Doctor of Philosophy in PhD in Neuroscience in 2015/06/10 by The University of Manchester School of Biological Sciences. Is Collaboration with Prof. Phillip Popovich in The Ohio State University College of Medicine, Collaboration with Prof. Elizabeth Bradbury in Wolfson Center for Age-related Diseases, King´s College of London , Principal Investigator in Universidade Católica Portuguesa Faculdade de Medicina and Lecturer in Universidade Católica Portuguesa. Published 11 articles in journals. Has 4 patent(s) registered. Organized 4 event(s). Participated in 13 event(s). Co-supervised 2 PhD thesis(es). Supervised 3 MSc dissertation(s) e co-supervised 1. Has received 11 awards and/or honors. Participates and/or participated as PhD Student Fellow in 1 project(s), Post-doc in 4 project(s), Post-doc Fellow in 1 project(s) and Principal investigator in 3 project(s). Works in the area(s) of Medical and Health Sciences. In his curriculum Ciência Vitae the most frequent terms in the context of scientific, technological and artistic-cultural output are: Lesão da espinal medula, ; Spinal Cord; Spinal Cord Injury; Neurorepair; Behaviour; Alzheimer´s disease; Obesity; High-fat diet; Blood-brain barrier; Periphery; Memory; Regeneration ; Senescence; Senescent Cells; Endothelial cells; Spinal cord Injury; Endothelial; Genes; Zebrafish; Mouse; Endothelial Cells; Animal Behaviour; Animals; Cell Differentiation; Ependyma; Mammals; Mice; Neural Stem Cells; Neuroglia; Developmental Biology; Cell Biology; General Biochemistry, Genetics and Molecular Biology; Molecular Biology; Neurosciences; FOS: Clinical medicine; Model organisms; Synthetic Biology; Imaging; Tumour Biology; Signalling & Oncogenes; Gene Expression; Genetics & Genomics; Genome Integrity & Repair; Human Biology & Physiology; Microfabrication & Bioengineering; Stem Cells; Chemical Biology & High Throughput; Infectious Disease; Ecology,Evolution & Ethology; Immunology; Computational & Systems Biology; Regenerative Medicine; Biologia Molecular e Celular; Desenvolvimento; Envelhecimento e Cancro; Infeção e Imunidade; Neurociências e Comportamento; Biologia Celular e do Desenvolvimento; Imunologia; Infecção; Neurociências; .
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Identification

Personal identification

Full name
Isaura Martins

Citation names

  • Martins, Isaura

Author identifiers

Ciência ID
5D14-4AD4-F366
ORCID iD
0000-0002-1329-7769

Email addresses

  • ismartins@ucp.pt (Professional)

Websites

Knowledge fields

  • Medical and Health Sciences

Languages

Language Speaking Reading Writing Listening Peer-review
English Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
Education
Degree Classification
2020 - 2020
Concluded
 Trends in CNS Regenerative Medicine (Outros)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2018/09 - 2018/09
Concluded
 Advanced Neuroscience Courses (Outros)
Major in Spinal Cord Injury
Neuroscience School of Advanced Studies, Italy
2017 - 2017
Concluded
 Spinal Cord Injury Training Program (Outros)
The Ohio State University, United States
2011/04/01 - 2015/06/10
Concluded
 PhD in Neuroscience (Doctor of Philosophy)
Major in Neuroscience
The University of Manchester School of Biological Sciences, United Kingdom
"The effect of a high-fat diet in health and in an animal model of Alzheimer's disease: a gender comparison study" (THESIS/DISSERTATION)
 Minor corrections
2008/09/01 - 2010/07/16
Concluded
 Bioquímica (Mestrado integrado)
Major in Neuroscience
Universidade de Coimbra, Portugal
"Neuroprotection by leptin and ghrelin against amyloid-beta toxicity in hippocampal neurons. Relevance for therapeutic intervention in Alzheimer's disease. " (THESIS/DISSERTATION)
 17
2005/09/01 - 2009/09/01
Concluded
 Bioquímica (Licenciatura)
Major in Bioquímica
Universidade de Coimbra, Portugal
"The role of mitochondrion – the importance of Rh0 cells in Alzheimer's disease." (THESIS/DISSERTATION)
 14
Affiliation

Science

Category
Host institution 		Employer
2024/12/10 - Current Principal Investigator (Research) Universidade Católica Portuguesa Faculdade de Medicina, Portugal
Universidade Católica Portuguesa Centro de Investigação Interdisciplinar em Saúde, Portugal
2024/10/12 - 2025/03/31 Visiting Researcher (Research) Gulbenkian Institute for Molecular Medicine, Portugal
Instituto de Medicina Molecular, Portugal
2023/06/01 - 2024/10/05 Contracted Researcher (Research) Instituto de Medicina Molecular, Portugal
2015/12/03 - 2023/05/31 Postdoc (Research) Instituto de Medicina Molecular, Portugal
2016/11/01 - 2016/12/01 Visiting Researcher (Research) Deutsches Krebsforschungszentrum, Germany
Deutsches Krebsforschungszentrum, Germany

Teaching in Higher Education

Category
Host institution 		Employer
2025/01/01 - Current Lecturer (University Teacher) Universidade Católica Portuguesa, Portugal

Others

Category
Host institution 		Employer
2022/01 - Current Collaboration with Prof. Phillip Popovich The Ohio State University College of Medicine, United States
2018/04 - 2020/01/01 Colaboration with Prof Caetano Reis e Sousa Francis Crick Institute, United Kingdom
Francis Crick Institute, United Kingdom
2017/05/07 - 2017/05/19 Student of the Craig Nelson Foundation-funded Spinal Cord Injury Research Training Program The Ohio State University, United States
Projects

Grant

Designation Funders
2023/01/15 - Current Endothelial CD9 as a new anti-inflammatory target to promote spinal cord repair
2022.05669.PTDC
Principal investigator
Instituto de Medicina Molecular, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2024/07/01 - 2026/06/30 MYLIP_PRINT: exploiting the role of MYLIP positive pericytes in SCI
WFL-PT-19/24
Principal investigator
Wings for Life Spinal Cord Research Foundation, United Kingdom
Ongoing
2023/09/01 - 2025/03/31 CD9/MYLIP_AGEnts: Targeting pericytes to prevent neuroinflammation and promote barrier integrity after spinal cord injury
NA
Principal investigator
Morton Cure Paralysis Fund Minnesota, United States
 Morton Cure Paralysis Fund Minnesota
Ongoing
2020/12/01 - 2023/12/31 Senescent cells and their secretory phenotype: novel targets for spinal cord repair
MC-36-2020
Post-doc
Instituto de Medicina Molecular, Portugal
 Santa Casa da Misericórdia de Lisboa
Ongoing
2017/04/01 - 2023/05/31 Angiocrine factors as modulators of spinal cord regeneration
SFRH/BPD/118051/2016
Post-doc Fellow
Instituto de Medicina Molecular, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2019/10/01 - 2022/09/30 Targeting induced-senescent cells: a novel approach to promote spinal cord regeneration in mamals
HR18-00187
Post-doc
Instituto de Medicina Molecular, Portugal
 Caixa d'Estalvis i Pensions de Barcelona
Ongoing
2018/10/01 - 2021/09/30 Modulation of vascular repair during spinal cord regeneration
PTDC/BIA-BID/28572/2017
Post-doc
Instituto de Medicina Molecular, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2018/10/01 - 2021/09/30 The function of induced-senescent cells in spinal cord regeneration
PTDC/MED-NEU/30428/2017
Post-doc
Instituto de Medicina Molecular, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2011/04/01 - 2015/03/31 Effects of a high-fat diet in health and in Alzheimer´s disease: a gender comparison study
SFRH/BD/73041/2010
PhD Student Fellow
The University of Manchester, United Kingdom
 Fundação para a Ciência e a Tecnologia
Concluded

Contract

Designation Funders
2021/01/01 - 2025/12/31 Instituto de Medicina Molecular João Lobo Antunes
LA/P/0082/2020
10.54499/LA/P/0082/2020
Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2019/01/01 - 2019/12/31 Instituto de Medicina Molecular - IMM
UID/BIM/50005/2019
Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Conference abstract
  1. Isidro, Ana Filipa; Domingos, Inês; Ribeiro, Daniel; Neves-Silva, Dalila; Quitéria, Raquel; Martins, Isaura; Saúde, Leonor. Corresponding author: Saúde, Leonor. "The role of p16+ cells on spinal cord neuroprotection and repair after an injury". Paper presented in 4th Meeting Spinal Cord Injury PT Researchers, Lisboa, 2024.
Conference paper
  1. Martins, Isaura; Allan, Stuart; Lawrence, Catherine. "THE EFFECT OF RESVERATROL SUPPLEMENTATION ON THE EFFECTS OF A HIGH-FAT DIET IN A 3XTGAD FEMALE MOUSE MODEL OF ALZHEIMER'S DISEASE". Paper presented in Alzheimer's Association International Conference, Copenhaga, 2014.
    10.1016/j.jalz.2014.05.648
  2. Martins, Isaura; Knight, Elysse; Allan, Stuart; Lawrence, Catherine. "Effects of a high-fat diet on the cerebrovasculature and neuroinflammation in an experimental model of Alzheimer's disease". Paper presented in Alzheimer´s Association International Conference, Vancouver, 2012.
    10.1016/j.jalz.2012.05.1263
Conference poster
  1. Neves-Silva, Dalila; Isa Fernandes Mota; Madalena Pires; Leonor Saúde; Martins, Isaura. Corresponding author: Martins, Isaura. "IDOLizing pericytes regulatorsof cardiometabolic effects after spinal cord inury". Paper presented in XIX Meeting Portuguese Society for Neurosciences, 2025.
  2. Ribeiro, Daniel; Isidro, Ana Filipa; Martins, Isaura; Leonor Saúde; Joao Pedro de Magalhaes. "Identifying injury-induced cellular senescence in the spinal cord by single cell RNA-seq". Paper presented in 4th International Meeting of the Portuguese Research Network on Spinal Cord Injury, 2024.
  3. Ribeiro, Daniel; Isidro, Ana Filipa; Martins, Isaura; Magalhaes, Joao; Saúde, Leonor. "Single cell analysis of the spinal cord reveals a persistent, injury-induced neuronal cell state". Paper presented in 13th EMBO Young Scientists¿ Forum, 2023.
  4. Martins, Isaura; Neves-Silva, Dalila; Ascensão-Ferreira, Mariana; Ribeiro, Daniel; Isidro, Ana Filipa; Dias, Ana Filipa; Quitéria, Raquel; et al. Corresponding author: Martins, Isaura. "CD9 and MYLIP as two new vascular players in spinal cord injury". Paper presented in 13th EMBO Young Scientists¿ Forum, 2023.
  5. Neves-Silva, Dalila; Martins, Isaura; Rebocho da Costa, Mariana; Quitéria, Raquel; Saúde, Leonor. "The right time to "scar"". Paper presented in XVI CAML · VI NeurULisboa PhD Students Meeting, 2023.
  6. Isidro, Ana Filipa; Medeiros, Alexandra M.; Martins, Isaura; Neves-Silva, Dalila; Saúde, Leonor; Mendes, César S.. Corresponding author: Mendes, César S.. "Taking a walk on the acrylic slide: Using the MouseWalker to quantify locomotor dysfunction in a mouse model of spinal cord injury". Paper presented in XVI CAML / VI NeurULisboa PhD Students Meeting, 2023.
  7. Ribeiro, Daniel; Isidro, Ana Filipa; Martins, Isaura; Saúde, Leonor. "A Single-cell Atlas of the Mouse Spinal Cord during the Acute and Chronic Injury Response Phases". Paper presented in 2nd International Meeting of the Portuguese Research Network on Spinal Cord Injury, 2022.
  8. Isidro, Ana Filipa; Ribeiro, Daniel; Martins, Isaura; Saúde, Leonor. Corresponding author: Saúde, Leonor. "The role of induced senescent cells after spinal cord injury". Paper presented in XV CAML/ V NeurULisboa Annual PhD Students Meeting, 2022.
  9. Neves-Silva, Dalila; Martins, Isaura. "Mimicking the Zebrafish Extracellular Matrix Profile in Mammals to Promote Spinal Cord Repair". 2021.
  10. "Targeting senescent cells improves functional recovery after spinal cord injury". 2021.
  11. Isidro, Ana Filipa; Ribeiro, Daniel; Martins, Isaura; Saúde, Leonor. Corresponding author: Saúde, Leonor. "The role of induced senescent cells on spinal cord injury". Paper presented in XIV CAML . IV NeurULisboa Annual PhD Students Virtual Meeting, 2021.
  12. Martins, Isaura. "The Endothelial Cells Transcriptome after Spinal Cord Injury A tale of two opposite models: Zebrafish vs Mouse". Paper presented in 21st Spinal Research Network Meeting London, 2019.
  13. Martins, Isaura. "Angiocrine Factors as Modulatores of Spinal Cord Regeneration". Paper presented in Lesões Vertebro Medulares- LVM Meeting 2016, 2016.
  14. Martins, Isaura. "The effect of resveratrol supplementation on the effects of a high-fat diet in 3xTgAD female mouse model of Alzheimer diseases". Paper presented in Alzheimer's Association International Conference 2014, 2014.
  15. Martins, Isaura. "Comparison of the effects of a high-fat diet (HFD) in male and female Alzheimer's disease mice". Paper presented in Alzheimer's Research UK Conference 2014, 2014.
  16. Martins, Isaura. "The Effect of High-Fat Diet in the Triple Transgenic Mouse Model of Alzheimer's Disease". Paper presented in Alzheimer's Research UK Conference 2013, 2013.
  17. Martins, Isaura. "Effects of a High-Fat Diet on the Cerebrovasculature and Neuroinflammation in an Experimental Model of Alzheimer's Disease". Paper presented in Alzheimer's Association International Conference 2012, 2012.
  18. Martins, Isaura. "The effect of high-fat diet on neurovascular dysfunction in a animal model of Alzheimer's disease (3xTgAD)". Paper presented in 7th International Symposium on Neuroprotection and Neurorepair 2012, 2012.
  19. Martins, Isaura; Gomes, Sílvia; Costa, Rui; Resende, Rosa; Oliveira, Catarina R; Pereira, Cláudia Fragão. "Ghrelin and leptin protect hippocampal neurons against Aß-induced toxicity. Relevance for therapeutic intervention in Alzheimer’s disease.". Paper presented in XVII National Congress of the Portuguese Biochemical Society, 2010.
  20. Martins, Isaura. "Effect of leptin and ghrelin in hippocampal neurons against Alzheimer´s disease neurotoxins – amyloid-beta peptide". Paper presented in XVII National Congress of Biochemistry, 2010.
  21. Martins, Isaura. "Ghrelin and leptin protect hippocampal neurons and hypothalamic cells against Aß-induced toxicity. Relevance for therapeutic intervention in Alzheimer´s disease". Paper presented in Second National Meeting on Medicinal Chemistry, 2010.
  22. Martins, Isaura. "Leptin and Ghrelin protect against Aß-induced toxicity in hippocampal and hypothalamic neurons". Paper presented in Network of European Neuroscience Institutes, Final Annual Network Meeting, 2010.
Journal article
  1. Martins, Isaura; Neves-Silva, Dalila; Ascensão-Ferreira, Mariana; Dias, Ana Filipa; Ribeiro, Daniel; Isidro, Ana Filipa; Quitéria, Raquel; et al. Corresponding author: Martins, Isaura. "Mouse Spinal Cord Vascular Transcriptome Analysis Identifies CD9 and MYLIP as Injury-Induced Players". International Journal of Molecular Sciences 24 7 (2023): 6433. http://dx.doi.org/10.3390/ijms24076433.
    10.3390/ijms24076433
  2. Isidro, Ana Filipa; Medeiros, Alexandra M.; Martins, Isaura; Neves-Silva, Dalila; Saúde, Leonor; Mendes, César S.. "Using the MouseWalker to Quantify Locomotor Dysfunction in a Mouse Model of Spinal Cord Injury". Journal of Visualized Experiments 193 (2023): http://dx.doi.org/10.3791/65207.
    10.3791/65207
  3. Bruno Frederico; Martins, Isaura; Diana Chapela; Francesca Gasparrini; Probir Chakravarty; Tobias Ackels; Cécile Piot; et al. "DNGR-1-tracing marks an ependymal cell subset with damage-responsive neural stem cell potential.". Developmental cell 57 (2022):
    Open access • 10.1016/j.devcel.2022.07.012
  4. Paramos-de-Carvalho, Diogo*; Martins, Isaura*; Cristóvão, Ana Margarida; Dias, Ana Filipa; Neves-Silva, Dalila; Pereira, Telmo; Chapela, Diana; et al. "Targeting senescent cells improves functional recovery after spinal cord injury". *shared first-author. Cell Reports 36 1 (2021): 109334. http://dx.doi.org/10.1016/j.celrep.2021.109334.
    10.1016/j.celrep.2021.109334
  5. Paramos-de-Carvalho, Diogo*; Martins, Isaura (5D14-4AD4-F366)*; Cristovão, Ana Margarida; Dias, Ana Filipa; Neves-Silva, Dalila; Pereira, Telmo; Chapela, Diana; et al. "Depletion of senescent cells improves functional recovery after spinal cord injury". * These two authors contributed equally to this work, bioRxiv (2020): https://www.biorxiv.org/content/10.1101/2020.10.28.358762v1.full.
    10.1101/2020.10.28.358762
  6. Chapela, Diana; Sousa, Sara; Martins, Isaura; Cristóvão, Ana Margarida; Pinto, Patrícia; Corte-Real, Sofia; Saúde, Leonor. "A zebrafish drug screening platform boosts the discovery of novel therapeutics for spinal cord injury in mammals". Scientific Reports 9 1 (2019): http://dx.doi.org/10.1038/s41598-019-47006-w.
    10.1038/s41598-019-47006-w
  7. Martins, Isaura V.A.; Rivers-Auty, Jack; Allan, Stuart M.; Lawrence, Catherine B.. "Mitochondrial Abnormalities and Synaptic Loss Underlie Memory Deficits Seen in Mouse Models of Obesity and Alzheimer’s Disease". Journal of Alzheimer's Disease 55 3 (2016): 915-932. http://dx.doi.org/10.3233/jad-160640.
    10.3233/jad-160640
  8. Knight, Elysse M.; Martins, Isaura V.A.; Gümüsgöz, Sarah; Allan, Stuart M.; Lawrence, Catherine B.. "High-fat diet-induced memory impairment in triple-transgenic Alzheimer's disease (3xTgAD) mice is independent of changes in amyloid and tau pathology". Neurobiology of Aging 35 8 (2014): 1821-1832. http://dx.doi.org/10.1016/j.neurobiolaging.2014.02.010.
    10.1016/j.neurobiolaging.2014.02.010
  9. Gomes, S.; Martins, I.; Fonseca, A. C. R. G.; Oliveira, C. R.; Resende, R.; Pereira, C. M. F.. "Protective Effect of Leptin and Ghrelin against Toxicity Induced by Amyloid-ß Oligomers in a Hypothalamic cell Line". Journal of Neuroendocrinology 26 3 (2014): 176-185. http://dx.doi.org/10.1111/jne.12138.
    10.1111/jne.12138
  10. Martins, I.; Gomes, S.; Costa, R.O.; Otvos, L.; Oliveira, C.R.; Resende, R.; Pereira, C.M.F.. "Leptin and ghrelin prevent hippocampal dysfunction induced by Aß oligomers". Neuroscience 241 (2013): 41-51. http://dx.doi.org/10.1016/j.neuroscience.2013.02.062.
    10.1016/j.neuroscience.2013.02.062
  11. Costa, Rui O.; Ferreiro, Elisabete; Martins, Isaura; Santana, Isabel; Cardoso, Sandra M.; Oliveira, Catarina R.; Pereira, Cláudia M.F.. "Amyloid ß-induced ER stress is enhanced under mitochondrial dysfunction conditions". Neurobiology of Aging 33 4 (2012): 824.e5-824.e16. http://dx.doi.org/10.1016/j.neurobiolaging.2011.04.011.
    10.1016/j.neurobiolaging.2011.04.011
Thesis / Dissertation
  1. Martins, Isaura. "Effects of a high-fat diet in health and in Alzheimer´s disease: a gender comparison study". PhD, The University of Manchester, 2015.
  2. Martins, Isaura. "Neuroprotection by leptin and ghrelin against amyloid-beta toxicity in hippocampal neurons. Relevance for therapeutic intervention in Alzheimer's disease". Master, Universidade de Coimbra Faculdade de Ciencias e Tecnologia, 2010.
  3. Martins, Isaura. "The role of mitochondrion – the importance of Rh0 cells in Alzheimer's disease.". Degree, Universidade de Coimbra Faculdade de Ciencias e Tecnologia, 2009.

Intellectual property

Patent
  1. Martins, Isaura; Saúde, Leonor; Neves-Silva, Dalila. 2023. "“Treatmenet of Spinal Injury”". Portugal.
    Pending
  2. Paramos-de-Carvalho, Diogo; Martins, Isaura; Jacinto, António; Saúde, Leonor. 2020. "The use of senolytic compounds in the treatment of spinal cord injury". Portugal.
    Granted/Issued
  3. Paramos-de-Carvalho, Diogo; Martins, Isaura; Jacinto, António; Saúde, Leonor. 2020. "Treatment of spinal cord injury (PCT/EP2020/07576)". Portugal.
    Granted/Issued
  4. Chapela, Diana; Côrte-Real, Sofia; Saúde, Leonor; Martins, Isaura; Sousa, Patrícia Filipa Saraiva de. 2020. "Eletriptan Hydrobromide for treatment of spinal cord injury and improvement of locomotor function". Portugal.
    Pending
Provisional application for patent
  1. 2023. "Treatment of Spinal Injury".
    Protected
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2025/04/10 Neurovascular interactions in spinal cord injury CMS Seminars
Católica Medical School
2023/10/27 Vascular therapeutic approaches to improve spinal cord repair: CD9 and MYLIP as two new vascular injury-induced players - Keynote Speaker Medical Technologies in Spinal Cord Injury
Universidade de Aveiro (Aveiro, Portugal)
2023/03/03 Mouse spinal cord vascular transcriptome analysis identifies CD9 and MYLIP as injury-induced players Building Bridges in Biology Symposium
Instituto Ciência Gulbenkian - IGC (Lisboa, Portugal)
2022/06/03 Endothelial cells as modulators of spinal cord regeneration: a tale of two models, zebrafish and mouse
NOVA Medical School
2022/05/05 Targeting Senescent Cells Improves Functional Recovery After Spinal Cord Injury
(Lisboa, Portugal)
2022/04/06 Targeting Senescent Cells Improves Functional Recovery After Spinal Cord Injury
Universidade de Coimbra (Coimbra, Portugal)
2022/03/19 Targeting Senescent Cells Improves Functional Recovery After Spinal Cord Injury Central Nervous System Injury and Repair
Gordon Research Seminar (GRS) (Oxnard , United States)
2021/12/15 Improving spinal cord repair: from targeting senescence to endothelial cells and beyond UC-Biotech Seminars
UC-Biotech (Coimbra, Portugal)
2020/12/11 Senescent cells as a new players in Spinal Cord Injury. A tale of two opposite models: Zebrafish vs Mouse Development in Action (DiA) Meeting
Instituto de Investigação e Inovação em Saúde (i3S) - Universidade do Porto (Porto, Portugal)
2020/11/02 Senescent cells as a new players in Spinal Cord Injury. A tale of two opposite models: Zebrafish vs Mouse International Online Spinal Cord Injury Research Seminars (i-OSCIRS)
(United States)
2019/05 The Endothelial Cells Transcriptome after Spinal Cord Injury. A tale of two opposite models: Zebrafish vs Mouse PostDoc Day Instituto de Medicina Molecular
(Lisboa, Portugal)
2018/11 Endothelial cells and spinal cord injury Lisbon Area PostDoctoral Meeting 2018
(Lisboa, Portugal)
2017/05 Angiocrine factors as potential modulators of spinal cord regeneration Lesões vertebro medulares (LVM) Meeting
(Porto, Portugal)
2014/07 The effect of a high-fat diet on an animal model of Alzheimer's disease Neuroscience Symposium
University of Manchester (Manchester, United Kingdom)
2014/05 Resveratrol supplementation on the effects of a high-fat diet in female 3xTgAD mice PhD Conference 2014 – University of Manchester
University of Manchester (Manchester, United Kingdom)
2014/03 Comparison of the effects of a high-fat diet (HFD) in male and female Alzheimer's disease mice PhD day Alzheimer's Research UK Conference 2014
Alzheimer´s Research UK (Oxford, United Kingdom)
2013/06 The role of the cerebrovasculature in the detrimental effect of a high-fat diet on Alzheimer's disease Alzheimer's Research Trust Manchester Meeting
Alzheimer´s Research Trust (Manchester, United Kingdom)
2013/05 The effect of high fat diet in triple transgenic mouse model of Alzheimer's disease PhD Conference 2013 – University of Manchester
University of Manchester (Manchester, United Kingdom)
2012/02 Effects of a high-fat diet on the cerebrovasculature and neuroinflammation in an experimental model of Alzheimer´s disease Alzheimer's Research Trust Manchester Meeting
Alzheimer´s Research Trust (Manchester, United Kingdom)
2010/10 Ghrelin and leptin signal pathways in the brain: towards novel disease-modifying drugs for Alzheimer's disease.” Angelini University Award 09/10
Angelini (Lisboa, Portugal)
2010/06 Neuroprotection by leptin and ghrelin against amyloid-beta toxicity in hippocampal neurons. Relevance for therapeutic intervention in Alzheimer's disease 24ª Reunião do Grupo de Estudos de Envelhecimento Cerebral e Demência
(Tomar, Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2020/09/01 - Current The role of induced-senescent cells in spinal cord injury
Co-supervisor
Instituto de Medicina Molecular, Portugal
2024/09/01 - 2025/08/31 Uncovering the role of MYLIP-expressing pericytes as new regulators of neuroinflammation and blood spinal cord barrier integrity after spinal cord injury
Supervisor of Madalena Pires
 Master Biomedical Research (Master)
Instituto de Medicina Molecular, Portugal
2019/09/01 - 2024/07/30 Using the regenerative potential of zebrafish extracellular matrix to promote spinal cord repair in mammals
Co-supervisor
Instituto de Medicina Molecular, Portugal
2021/10/05 - 2022/09/30 The senescent profile in peripheral organs after a spinal cord injury
Co-supervisor
 Mestrado Integrado Medicina Veterinária (Master)
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
2020/03/01 - 2020/04/30 The role of periphery in spinal cord injury
Supervisor
Universidade do Algarve Departamento de Ciências Biomédicas e Medicina, Portugal
2018/07/01 - 2018/08/02 The Endothelial Cells Transcriptome after Spinal Cord Injury
Supervisor
 SCORE Research Exchange - Intercâmbios em Investigação Científica, da IFMSA (Other)
Samarskij gosudarstvennyj medicinskij universitet, Russia
2013/09 - 2014/09 Effect of High Fat Diet and Alzheimer's Disease on Peripheral Inflammation and Oxidative Stress: Potential of Resveratrol to Attenuate Peripheral Mechanisms and Cognition.
Supervisor
 Masters of Research in the Faculty of Life Sciences (Master)
The University of Manchester, United Kingdom

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2024/09/16 - Current Organization of the 4th Spinal Cord Injury Portuguese Meeting (2024/09/16)
Conference (Member of the Organising Committee)
 Gulbenkian Institute for Molecular Medicine, Portugal
2021/12/03 - Current "Rir para não chorar" - A round table to talk about mental health and the impact of the pandemics in the brain. This event took place in a coffee shop in Coimbra and joined one Neuroscientist (Dr. Catarina Gomes), one Psychiatrist (Dr. Miguel Bajouco) and two comedians (Rita Leão e João Moreira). (2021/12/03 - 2021/12/03)
Round table (Member of the Organising Committee)
 Fala-me Neuro, Portugal
2020/11/01 - 2021/12/31 "Fala-me Neuro" is a portuguese science communication project developed to be accessible to everyone who wants to know more about Neurosciences, from credible sources in a simple and lay way in portuguese. It was developed and organised by a group of young neuroscientists from all over Portugal and counts with the support of Sociedade Portuguesa de Neurociências (SPN). (2021/02/13)
Other (Co-organisor)
 Sociedade Portuguesa de Neurociências, Portugal
2009/04/18 - 2009/04/18 Commemoration of 30th anniversary of the Biochemistry course in Portugal (2009/04/18 - 2009/04/19)
Symposium (Member of the Organising Committee)
 Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2021/11/24 - Current Invitation to talk at Escola nº1 de Rio de Mouro for the "Dia do Cientista" event.
Other
 Dia do Cientista
Escola Nº1 de Rio de Mouro, Portugal
2020/11/29 - Current Speaker for "Dia do Cientista 202" in Pavilhão do Conhecimento - Ciência Viva
Other
 Dia do Cientista
Ciência Viva, Portugal
2020/11/27 - Current Part of the members of the virtual round table for "Noite dos Investigadores 2020"
Round table
 Noite dos Investigadores Virtual 2020
Instituto de Medicina Molecular, Portugal
2017/06 - Current Speaker at the 17º PubhD in Lisbon about spinal cord regeneration (https://pubhdlisboa.wordpress.com/2017/04/30/17o-pubhd-de-lisboa-em-revista/)
Round table
 17ºPubhD Lisbon
2023/05/22 - 2023/05/24 Invited speaker for “Com Pés e Cabeça”, a public engagement event that talks about research in the fields of medicine, human biology and health.
Festival
 Pint of Science Festival 2023
Pint of Science , Portugal
2020/11/10 - 2020/11/19 Workshop Neuro-omics, including the bases and knowledge of RNAsequencing and proteomics design and analysis
Workshop
 Stanford Neuro-Omics 2020 Virtual Workshop
Stanford Neurosciences Institute, United States
2020/03/02 - 2020/03/06 Advanced Course - Recent Trends in CNS Regenerative Medicine
Other
 Advanced Course - Recent Trends in CNS Regenerative Medicine
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2018/09/08 - 2018/09/15 Spinal Cord Injury Course from Neuroscience School of Advanced Studies (NSAS) in Venice, Italy Neuroscience School of Advanced Studies (NSAS) in Venice
Neuroscience School of Advanced Studies, Italy
2017/05/07 - 2017/05/19 The Craig Nelson Foundation-funded Spinal Cord Injury Research Training Program. The top research training program in the field of spinal cord injury where during two weeks only a dozen of participants are selected to learn the biological and molecular basis of spinal cord injury together with training in surgery procedures and animal models and techniques from histology to electrophisiology.
Workshop
 The Craig Nelson Foundation-funded Spinal Cord Injury Research Training Program
The Ohio State University, United States
2016/06/20 - 2016/06/22 EMBO Leadership and Management Skills Course
Workshop
 Leadership and Management Skills Course
HFP Consulting, Germany
2015/09 - 2016 Participating in Noite dos Investigadores (https://noitedosinvestigadores.org/)
Other
 Noite dos Investigadores 2015, 2016
Instituto de Medicina Molecular, Portugal
2011/06/01 - 2015/01/04 Several Public Engagement Activities
Other
 Brain Bus, Brain Awareness Week
The University of Manchester Faculty of Biology Medicine and Health, United Kingdom
2014/05/01 - 2014/11/30 Volunteer at Central Manchester University Hospital,Manchester, United Kingdom
Other
 Volunteer

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2025/01/30 Impact and Transcriptomic Analysis of the Effect of the Secretome of Adipose Tissue derived Stem Cells in an in vitro Model of Spinal Cord Injury
(Thesis) Main arguer
 Ana Teresa Palha Sousa (Master)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2025/01/28 Compound Library Screening for Neural Repair: Finding New Drugs for Old Problems
(Thesis) Main arguer
 Luís Carlos Sousa Fernandes (Master)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2022/12/07 The effects of Metabolic Reprogramming during Zebrafish Tissue Regeneration
(Thesis) Arguer
 Jorge Miguel Ramalho Borbinha (PhD)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal

Ad Hoc journal article review

Journal title (ISSN) Publisher
2022/12/02 - 2023/02/10 Frontiers of Neuroscience

Association member

Society Organization name Role
2024/11/01 - Current ALBA
2023/09/01 - Current EUROSPINE
2023/06/01 - Current World Women in Neuroscience (WWN) Member and mentor
2021/12/03 - Current Sociedade Portuguesa de Neurociências (SPN) Member
2016/02 - 2017/03 Postdoctoral Association of Instituto de Medicina Molecular (iMM) Member of the Postdoctoral Association of Instituto de Medicina Molecular (iMM), organised several postdoctoral activities such as Postdoc Day at iMM, Postdoc Retreat and a Gender Balance in Science Debate to promote awareness of women in science with several important scientists worldwide such as the 2013 Laureate UNESCO-L´Oreal “For Women in Science” Reiko Kuroda and the EMBO Director Maria Leptin (https://justnews.pt/noticias/instituto-de-medicina-molecular-acolhe-debate-sobre-a-igualdade-de-generos-na-ciencia#.XWUs5OhKg2w)
2012 - 2014 Understanding Animal Research UK (http://www.understandinganimalresearch.org.uk) Participating in school initiatives to share awareness regarding the use of animals in science.
2007/01/01 - 2009/12/06 Biochemistry Students Association, Coimbra Member (2007-2008) and Vice-President (2008-2009)

Committee member

Activity description
Role 		Institution / Organization
2021/02/13 - Current "Fala-me Neuro" is a portuguese science communication project developed to be accessible to everyone who wants to know more about Neurosciences, from credible sources in a simple and lay way in portuguese. It was developed and organised by a group of young neuroscientists from all over Portugal and counts with the support of Sociedade Portuguesa de Neurociências (SPN).
Member
 Fala-me Neuro, Portugal

Conference scientific committee

Conference name Conference host
2024/09/16 - Current 4th Spinal Cord Injury Portuguese Meeting

Consulting

Activity description Institution / Organization
2021/04/01 - 2021/06/30 Consultant for science writing - provided assistance with researching and drafting resource pages pertaining to rare diseases/neurosciences. Haymarket Media Inc, United States

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2025/03/11 - Current Master in Biopharmaceutical Sciences - Physiopathology of Neuroinflammation Master in Biopharmaceutical Sciences - Physiopathology of Neuroinflammation (Mestrado) Universidade de Lisboa Faculdade de Farmácia, Portugal
2012/01/01 - 2014/09/01 Demonstrator at University of Manchester in practical classes and lectures (Bachelor) The University of Manchester Faculty of Biology Medicine and Health, United Kingdom

Interview (newspaper / magazine)

Activity description Newspaper / Forum
2017/03/01 Sobre o papel da mulher na ciência e a pressão de cada uma seguir um caminho ditado. "Ser mulher, cientista ou chefe? Cada uma é como é." Diário de Notícias

Interview (tv / radio show)

Program Topic
2025/04/27 - Current Spinal Cast
2023/05/02 - 2023/05/02 O Futuro não está escrito - Rádio Movimento

Journal scientific committee

Journal title (ISSN) Publisher
2018/02/01 - Current Journal de Investigação Médica (JIM) Ponteditora

Mentoring / Tutoring

Topic Student name
2025/01/01 - Current World Women in Neuroscience Mentoring Program Maria Binu Jacob
Distinctions

Award

2025 SPN effective member Travel Grant
Sociedade Portuguesa de Neurociências, Portugal
2025 DMM Conference Travel Grant CTG-DMM25021825
The Company of Biologists Ltd, United Kingdom
2023 Outstanding Developmental Biology Paper Award 2023
Sociedade Portuguesa de Biologia do Desenvolvimento, Portugal
2022 Lídia Silva Santos Postdoctoral Achievement Award
Instituto de Medicina Molecular, Portugal
2022 Best oral Communication Award - I International Meeting on the Brain Vasculature
Sociedade Portuguesa de Neurociências, Portugal
2021 Pfizer Basic Research Award
Pfizer Portugal, Portugal
2013 Prize for best oral presentation in Neurosciences at the PhD Conference 2013

Other distinction

2022 Exploratory Research Projects Grant
Fundação para a Ciência e a Tecnologia, Portugal
2017 Sponsorship to attend SCITP 2017 Ohio State University
Craig H Neilsen Foundation, United States
2016 Postdoc Fellowship Grant - SFRH/BPD/118051/2016
Fundação para a Ciência e a Tecnologia, Portugal
2014 Travel grant to attend Alzheimer´s Association International Conference 2014 in Copenhagen, Denmark
Guarantors Of Brain, United Kingdom
2013 Travel grant to attend Alzheimer´s Association International Conference 2013 in Vancouver, Canada
2010 PhD Fellowship Grant - SFRH/BD/73041/2010
Fundação para a Ciência e a Tecnologia, Portugal