???global.info.a_carregar???
Since 2009, when she became an independent researcher, Alexandra R Fernandes has been involved in two main areas: Diagnostics and Therapy. Her research has been focusing: 1) development of novel diagnostic tools for the genetic diagnostics of cardiomyopathies. In the context of this area of research, she has been involved in several national and international collaborations. This research work has been translated to a diagnostic company HEARTGENETICS SA, where she was a co-founder (2013) and COO (between 2013-2015). 2) The application/validation of novel cancer diagnostics tools in clinical samples. Part of this research has been translated to Nano4 Global Lda, where she was a co-founder (2015) and presently COO. 3) The identification of new promising compounds for cancer therapy, in the characterization of their biological targets and their target delivery to cancer cells. She has been also interested in the identification of markers of resistance to cancer therapy (mostly in chronic myelogenous leukemia and breast cancer). To accomplish these goals, she has been using 2D/3D models of tumor cell lines, primary cultures of cancer patients, blood samples and more recently also in vivo studies using eggs embryos, zebrafish and mice. In the context of this area of research, she has been involved in several national and international collaborations and projects (>25). She has also been using the dog as a model organism for the study of canine mammary tumors. Unlike the man, dog does not respond to common therapy and surgery is the only resource. The current understanding of breast cancer women's help in identifying the biological mechanisms underlying this canine mammary tumors and new knowledge that will come from here can shed some light for new therapeutics. The aim is to study the proteome and the transcriptome of canine mammary tumors with different morphologies and stages to identify new fusion products, new mutations or miRNAs involved in tumor progression. The creation of a database of primary cultures and tissues is also an objective of this research. She developed a new cell line that has been licensed to Applied Biological Materials (ABM) Inc (https://www.abmgood.com/FR37-CMT-Tumor-Cells-T8002.html). She has been involved in Expert Evaluation of International R&D Projects and Grants (Austrian Science Fund I projects; ANR - Agence Nationale de la Researche; Czech Science Foundation, UK Welcome Trust, FCT/MCTES). Since 2009 she has been involved in several national and International funded Research Projects (5 has Principal Investigator (two International, three National) and 22 as Team member (three European, 19 National)). She has experience as a scientific adviser (Post-Doc Supervision: 4 (since 2013); PhD Supervision: 10 (since 2011); PhD Jury member in 10 PhD National Thesis and 3 PhD International Thesis; Master Supervision: 40 (since 2010); Master Jury: 81; Graduation Thesis Supervision: 60; Graduation Thesis Jury: >120; Erasmus - Post-Doc: 2; PhD students: 4; Master students: 1; graduation students: 7. She has published 10 book chapters, >150 papers in International Journals with referees, 3 papers in Proceedings of International Conferences (with referees), 3 papers in National Journals with referees. She has > 48 oral communications in International and National Meetings (with referees) and more than 100 communications in Panel.
Identificação

Identificação pessoal

Nome completo
Alexandra R Fernandes

Nomes de citação

  • Fernandes, Alexandra
  • Alexandra R Fernandes

Identificadores de autor

Ciência ID
021D-7DC8-C92F
ORCID iD
0000-0003-2054-4438
Google Scholar ID
https://scholar.google.pt/citations?user=7ZUgRWAAAAAJ&hl=pt-PT
Researcher Id
C-7465-2011
Scopus Author Id
7201782186

Endereços de correio eletrónico

  • ma.fernandes@fct.unl.pt (Profissional)

Telefones

Telefone
  • 212948530 (Profissional)

Moradas

  • Departamento Ciências da Vida, FCT-UNL. Caparica, 2829-516, Caparica, Almada, Portugal (Profissional)

Websites

Domínios de atuação

  • Ciências Médicas e da Saúde - Biotecnologia Médica - Diagnóstico e Terapias de Base Genética
  • Ciências Médicas e da Saúde - Biotecnologia Médica - Biotecnologia Aplicada à Saúde
  • Ciências Médicas e da Saúde - Medicina Básica - Genética Humana

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Francês Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1)
Alemão Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1)
Formação
Grau Classificação
2000/04/18
Concluído
Biotecnology (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
"A H+-ATPase da membrana plasmática e a resposta ao stress oxidativo, em particular ao stress pelo cobre, em Saccharomyces cerevisiae" (TESE/DISSERTAÇÃO)
Aproved
1995/09/01
Concluído
Engenharia Bioquímica (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
"n/a" (TESE/DISSERTAÇÃO)
Parte escolar - 17 valores
1994/09/05
Concluído
Engenharia Química (Ramo Biotecnologia) (Licenciatura)
Universidade de Lisboa Instituto Superior Técnico, Portugal
"n/a" (TESE/DISSERTAÇÃO)
15 valores
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento
Empregador
2015/01/01 - Atual Investigador principal (carreira) (Investigação) REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2015/01/01 - 2015 Investigador (Investigação) Universidade de Lisboa Centro de Química Estrutural, Portugal
2008/12/01 - 2014/12/31 Investigador (Investigação) Universidade de Lisboa Instituto Superior Técnico, Portugal
2009 - 2013 Investigador (Investigação) Universidade de Lisboa Centro de Química Estrutural, Portugal
2006 - 2008 Investigador (Investigação) Universidade de Lisboa, Portugal

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento
Empregador
2013/03/01 - Atual Professor Auxiliar (Docente Universitário) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2016 - 2018 Professor Auxiliar (Docente Universitário) Universidade Nova de Lisboa, Portugal
2013 - 2016 Professor Auxiliar (Docente Universitário) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2010/10/01 - 2013/02/28 Professor Associado (Docente Universitário) Universidade Lusófona de Humanidades e Tecnologias, Portugal
2009/04/01 - 2013/02/28 Assistente Convidado (Docente Universitário) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2000/04/20 - 2010/09/30 Professor Auxiliar (Docente Universitário) Universidade Lusófona de Humanidades e Tecnologias, Portugal
1998/04/20 - 2000/03/31 Assistente (Docente Universitário) Universidade Lusófona de Humanidades e Tecnologias, Portugal

Cargos e Funções

Categoria Profissional
Instituição de acolhimento
Empregador
2021/05/01 - Atual Coordenador Mestrado em Genética Molecular e Biomedicina Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Outros

Categoria Profissional
Instituição de acolhimento
Empregador
2015/12/14 - Atual Founder of Nano4Global. Lda Nano4 Global Lda, Portugal
2013/04/01 - 2015/09/30 Founder of Heartgenetics SA Shareholder of Heartgenetics HeartGenetics Genetics and Biotechnology SA, Portugal
2010/06/01 - 2013/03/01 Coordinator of the Master in Cancer Biology Universidade Lusófona de Humanidades e Tecnologias, Portugal
2009/10/01 - 2013/03/01 Coordinator of the Master in Biotechnology Engineering Universidade Lusófona de Humanidades e Tecnologias, Portugal
2010/09/01 - 2011/08/31 Invited assistant Professor (Coordinator of the Molecular Biotechnology Module in the Life Sciences PhD Program) Universidade do Porto, Portugal
2009/05/01 - 2011/05/12 Advisor of the Genetic and Cellular Biology Group of the Portuguese Society of Cardiology Sociedade Portuguesa de Cardiologia, Portugal
2009/10/01 - 2010/12/31 Coordinator of the Master in Development Biology Universidade Lusófona de Humanidades e Tecnologias, Portugal
2009/03/01 - 2010/09/30 Coordinator of the "Pós-Graduação Genética Clinica e Laboratorial" Universidade Lusófona de Humanidades e Tecnologias, Portugal
2005/09/01 - 2008/03/31 Molecular Biology Laboratory Director Centro de Genética Clínica e Patologia SA, Portugal
2000 - 2005 Pos-doc research Universidade de Lisboa Instituto Superior Técnico, Portugal
Projetos

Projeto

Designação Financiadores
2021/03/29 - 2024/03/28 Derivados de triptofanol para reativação de formas mutadas da p53 <br>
PTDC/QUI-QOR/1304/2020
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal

Associação para a Inovação e Desenvolvimento da FCT, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2021/03/01 - 2024/02/29 Fármacos de ruténio-péptido: flechas para alvejar seletivamente o cancro da mama
PTDC/QUI-QIN/0146/2020
Universidade de Lisboa Centro de Química Estrutural, Portugal

Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal

Associação para a Inovação e Desenvolvimento da FCT, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2018/08/01 - 2022/07/31 Nanomateriais Auto-Organizados Para Entrega Fotocontrolada de Fármacos e Genes
PTDC/QUI-COL/32351/2017
Associação para a Inovação e Desenvolvimento da FCT, Portugal

Universidade do Porto, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2019/02/01 - 2022/01/31 Valorização de Moléculas Isoladas de Anfíbios Aquáticos Portugueses
PTDC/BII-BIO/31158/2017
Investigador
Instituto de Biologia Molecular e Celular, Portugal

Associação para a Inovação e Desenvolvimento da FCT, Portugal

REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
Fundação para a Ciência e a Tecnologia

Governo da República Portuguesa Ministério da Ciência Tecnologia e Ensino Superior
Em curso
2019/01/31 - 2022/01/01 Quimica macrocíclica y organometálica – QUIMIOR.
1. CONSOLIDACIÓN 2019 GRC GI-1581
Investigador
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal

Universidade de Santiago de Compostela Facultade de Química, Espanha
Em curso
2019/01/01 - 2022/01/01 Synthesis of Heterocyclic Compounds for biological and technological applications
2. FAPESP:2018/00544-4
Investigador
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal

Fundação de Amparo à Pesquisa do Estado de São Paulo, Brasil
Em curso
2020/06 - 2021/12/31 ACTPHAST
ACTPHAST: Innovation Project Proposal project ID P2019 -36
ACTPHAST: Innovation Project Proposal project ID P2019 -36
Investigador
Nano4 Global Lda, Portugal
N/A
Concluído
2018/07/01 - 2021/12/31 SME Phase II
SME Phase II
Investigador responsável
Nano4 Global Lda, Portugal
Conseil de l'Union Europeenne
Concluído
2018/10/01 - 2021/09/30 Plataforma de Microfluidica Integrada para a deteção do cancro através de PCR digital de ADN livre circulante
PTDC/BTM-SAL/31201/2017
PTDC/BTM/SAL/31201/2017
Investigador
Associação para a Inovação e Desenvolvimento da FCT, Portugal

REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
Fundação para a Ciência e a Tecnologia

Governo da República Portuguesa Ministério da Ciência Tecnologia e Ensino Superior
Em curso
2018/09/01 - 2021/01/31 EraNet MAGICCELLGene: Localized MAGnetIC hyperthermia CELL-based GENE therapy for immune modulation.
EraNet MAGICCELLGene/2015
Investigador
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
Conseil de l'Union Europeenne
Em curso
2019 - 2021 Detecção e Caracterização de Nanopartículas Usando Nanoporos de Estado Sólido: Uma Abordagem Única Molécula
PTDC/NAN/MAT/31100/2017
PTDC/NAN-MAT/31100/2017
Investigador
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal

Universidade Nova de Lisboa, Portugal

Associação para a Inovação e Desenvolvimento da FCT, Portugal
Governo da República Portuguesa Ministério da Ciência Tecnologia e Ensino Superior

Conseil de l'Union Europeenne

Fundação para a Ciência e a Tecnologia
Em curso
2019 - 2021 Marine invertebrates as source of novel biotoxins: Investigating function and application through Polychaeta venomics
PTDC/BTA/28650/2017
Investigador
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
Governo da República Portuguesa Ministério da Ciência Tecnologia e Ensino Superior
Em curso
2019 - 2021 Novel photoinduced-molecules for cancer therapy
PTDC/QUI/CCL/032351/2017
Investigador
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
Governo da República Portuguesa Ministério da Ciência Tecnologia e Ensino Superior
2019 - 2021 The MARVEN Project -The Portuguese biotechnological database for marine animal venoms and toxins
FA_05_2017_007
Investigador
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
Fundo Azul
Em curso
2019 - 2021 Ionic liquids as a new platform for tuberculosis treatment (TB-ILs)
PTDC/QUI/QER/32406/2017
PTDC/QUI/QER/32406/2017
Investigador
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
Governo da República Portuguesa Ministério da Ciência Tecnologia e Ensino Superior
Em curso
2020/01/06 - 2020/06/01 Quick COVID-19 Detection (QuiCoviDe)
RESEARCH4COVID19/2020
Investigador
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
Concluído
2016/04/01 - 2020/03/30 RA DETECT - One Platform – multiple biomarker detection of Rheumatoid Arthritis
Era-Net - Inno Indigo 2015
Investigador
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
European Commission
Concluído
2016/07/03 - 2019/12/31 De pigmentos e toxinas: uma abordagem integradora ao potencial biotecnológico de um poliqueta marinho
PTDC/MAR-BIO/0113/2014
Investigador
Associação para a Inovação e Desenvolvimento da FCT, Portugal

Centro de Ciências do Mar e do Ambiente, Portugal

Egas Moniz Cooperativa de Ensino Superior CRL, Portugal

REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
Fundação para a Ciência e a Tecnologia

Koeki Zaidan Hojin Nakayama Hayao Kagaku Gijutsu Bunka Zaidan
Concluído
2016/05/02 - 2019/11/01 Avaliação da especificidade do hospedeiro e das interacções agente patogénico-hospedeiro em Streptococcus
PTDC/CVT-EPI/6685/2014
Investigador
Associação para a Inovação e Desenvolvimento da FCT, Portugal

REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
Fundação para a Ciência e a Tecnologia

Koeki Zaidan Hojin Nakayama Hayao Kagaku Gijutsu Bunka Zaidan
Concluído
2015/01/01 - 2018/01/01 Cytotoxicity and photo-cytotoxicity of nitrosyl ruthenium anticancer drug in aqueous solution or incorporated in a drug delivery system. An innovative purpose for metal based drug
2015/50101-3
Investigador responsável
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
Conselho Nacional de Desenvolvimento Científico e Tecnológico
Concluído
2017/06 - 2017/12 SME Phase I
SME Phase I
Investigador responsável
Nano4 Global Lda, Portugal
Concluído
2016/01/01 - 2017/01/01 Validation of Natural extracts for dermal applications
Vitrobio
Investigador responsável
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
Concluído
2013/06/01 - 2016/12/31 De pequenas moléculas bioactivas a uma abordagem ÓMICA integrada: Ferramentas de Espectrometria de Massa para a compreensão mecanística de propriedades farmacológicas e funcionais, toxicidade e respostas ao stress
RECI/QEQ-MED/0330/2012
Investigador
Universidade de Lisboa Centro de Química Estrutural, Portugal

Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal

Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal

Centro Hospitalar de Lisboa Central EPE, Portugal

Instituto Nacional de Saúde Doutor Ricardo Jorge, Portugal

Hospital Professor Doutor Fernando Fonseca EPE, Portugal
Fundação para a Ciência e a Tecnologia

Fundação para a Ciência e a Tecnologia, I.P.
Concluído
2013/01/01 - 2016/03/01 Silence is golden (siAu) - silencing the silencers via multifunctional gold nanoconjugates towards cancer therapy
PTDC/BBB-NAN/1812/2012
Investigador
Universidade de Lisboa Centro de Química Estrutural, Portugal

REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal

Universidade Nova de Lisboa Centro de Toxicogenómica e Saúde Humana, Portugal

Associação para a Inovação e Desenvolvimento da FCT, Portugal
Fundação para a Ciência e a Tecnologia, I.P.

Fundação para a Ciência e a Tecnologia
Concluído
2013/01/01 - 2016/01/01 Unraveling the host specificity within Streptococcus dysgalactiae subsp. dysgalactiae
PTDC/CVT-EPI/4651/2012
Investigador
Universidade de Lisboa Centro de Química Estrutural, Portugal

REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal

Associação para a Inovação e Desenvolvimento da FCT, Portugal
Fundação para a Ciência e a Tecnologia, I.P.

Fundação para a Ciência e a Tecnologia
Concluído
2015 - 2016 Evaluation of deep-sea animal lipid extracts as new natural anticancer cellular therapy
APCL|FCG 2014
Investigador responsável
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
Associação Portuguesa Contra a Leucemia
Concluído
2008/01/01 - 2010/01/01 Imatinib resistance and targets in Chronic Myeloid Leukaemia: post-genomic approaches using yeast as a model system
PTDC/SAU-FCF/71760/2006
Investigador
Centro de Genética Clínica e Patologia SA, Portugal
Governo da República Portuguesa Ministério da Ciência Tecnologia e Ensino Superior
Concluído
2007/01/01 - 2010/01/01 Mechanisms of resistance to Imatinib in Chronic Myeloid Leukemia
PTDC/SAU-GMG/71720/2006
Investigador
Centro de Genética Clínica e Patologia SA, Portugal

Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
Governo da República Portuguesa Ministério da Ciência Tecnologia e Ensino Superior

Fundação para a Ciência e a Tecnologia
Concluído
2006/01/02 - 2008/01/01 Elucidação das complexas redes de regulação que actuam na levedura sujeita a drogas/stresse químico: abordagens de expressão genómica e de bioinformática
PDCT/BIO/56838/2004
Universidade de Lisboa Instituto Superior Técnico, Portugal

Universidade de Lisboa Instituto Superior Técnico, Portugal

Instituto de Engenharia de Sistemas e Computadores Investigação e Desenvolvimento em Lisboa, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2005/01/01 - 2007/12/31 DBYeast: Infraestruturas e algoritmos para análise e identificação de redes de regulação genética
POSC/EIA/57398/2004
Instituto de Engenharia de Sistemas e Computadores Investigação e Desenvolvimento em Lisboa, Portugal

Universidade de Lisboa Instituto Superior Técnico, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2003/02/01 - 2005 Adaptation and resistance to organic acid food preservatives in yeast
Bolseiro de Pós-Doutoramento
Universidade do Algarve Faculdade de Ciências e Tecnologia
Concluído
2002 - 2004 Genomic-oriented studies on Saccharomyces cerevisiae
POCTI/BIO/38115/2001
Bolseiro de Pós-Doutoramento
Concluído
2002 - 2004 Resistência a benomil e outros fungicidas em Saccharomyces cerevisiae: papel de transportadores de múltiplas drogas e sua regulação
POCTI/AGG/38110/2001
Bolseiro de Pós-Doutoramento
Concluído
2001 - 2003 Strategies to accelerate the produtive biodegradation of several herbicides under environmental stress conditions
HERBICBIOREM 2001
Bolseiro de Pós-Doutoramento
European Union
Concluído

Outro

Designação Financiadores
2014/01/01 - 2017/01/01 Gold multifunctional nanoparticles for targeting cancer – Cetuximab
Merck-Serono
Investigador responsável
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal

Universidade de Lisboa Centro de Química Estrutural, Portugal
Concluído
Produções

Publicações

Artigo em conferência
  1. Catia M Machado; Francisco Couto; Alexandra R Fernandes; Susana Santos; Nuno Cardim; Ana T Freitas; Machado, C.M.; et al. "Semantic characterization of hypertrophic cardiomyopathy disease". 2010.
    10.1109/bibmw.2010.5703841
Artigo em revista
  1. Inês C. B. Martins; Andreia Forte; Hermínio P. Diogo; Luís R. Raposo; Pedro V. Baptista; Alexandra R. Fernandes; Luís C. Branco; M. Teresa Duarte. "A solvent-free strategy to prepare amorphous salts of folic acid with enhanced solubility and cell permeability". Chemistry–Methods (2022): https://doi.org/10.1002/cmtd.202100104.
    10.1002/cmtd.202100104
  2. Margarida Ferreira-Silva; Ana Catarina Faria da Silva; Manuela Carvalheiro; Sandra Simões; H. Susana Marinho; Paulo Marcelino; Maria Celeste Campos; et al. "Quercetin Liposomal Nanoformulation for Ischemia and Reperfusion Injury Treatment". Pharmaceutics (2022): https://www.mdpi.com/1999-4923/14/1/104.
    10.3390/pharmaceutics14010104
  3. Andrea Pinto; Catarina Roma-Rodrigues; Jas S. Ward; Rakesh Puttreddy; Kari Rissanen; Pedro V. Baptista; Alexandra R. Fernandes; João Carlos Lima; Laura Rodríguez. "Aggregation versus Biological Activity in Gold(I) Complexes. An Unexplored Concept". Inorganic Chemistry (2021): https://doi.org/10.1021/acs.inorgchem.1c02359.
    10.1021/acs.inorgchem.1c02359
  4. Bilal Abdulmawjood; Beatriz Costa; Catarina Roma-Rodrigues; Pedro V. Baptista; Alexandra R. Fernandes. "Genetic Biomarkers in Chronic Myeloid Leukemia: What Have We Learned So Far?". International Journal of Molecular Sciences 22 22 (2021): 12516-12516. https://doi.org/10.3390/ijms222212516.
    10.3390/ijms222212516
  5. Ana R. Jesus; Luís R. Raposo; Mário R. C. Soromenho; Daniela A. S. Agostinho; José M. S. S. Esperança; Pedro V. Baptista; Alexandra R. Fernandes; Patrícia M. Reis. "New Non-Toxic N-alkyl Cholinium-Based Ionic Liquids as Excipients to Improve the Solubility of Poorly Water-Soluble Drugs". Symmetry (2021): https://doi.org/10.3390/sym13112053.
    10.3390/sym13112053
  6. Joanna Palion-Gazda; André Luz; Luís R Raposo; Katarzyna Choroba; Jacek Nycz; Alina Bienko; Agnieszka Lewinska; et al. "Vanadium(IV) Complexes with Methyl-Substituted 8-Hydroxyquinolines: Catalytic Potential in the Oxidation of Hydrocarbons and Alcohols with Peroxides and Biological Activity". Molecules (2021): https://www.mdpi.com/1420-3049/26/21/6364.
    10.3390/molecules26216364
  7. Oscar A. Lenis-Rojas; Sandra Cordeiro; Marta Horta-Meireles; Jhonathan Angel Araujo Fernández; Sabela Fernández Vila; Juan Andrés Rubiolo; Pablo Cabezas-Sainz; et al. "N-Heterocyclic Carbene Iron Complexes as Anticancer Agents: In Vitro and In Vivo Biological Studies". Molecules 26 18 (2021): 5535-5535. https://doi.org/10.3390/molecules26185535.
    10.3390/molecules26185535
  8. Oscar Lenis-Rojas; Catarina Roma-Rodrigues; Alexandra Fernandes; Andreia Carvalho; Sandra Cordeiro; Jorge Guerra-Varela; Laura Sánchez; et al. "Evaluation of the In Vitro and In Vivo Efficacy of Ruthenium Polypyridyl Compounds against Breast Cancer". International Journal of Molecular Sciences 22 16 (2021): 8916-8916. https://doi.org/10.3390/ijms22168916.
    10.3390/ijms22168916
  9. Oscar A. Lenis-Rojas; Rui Cabral; Beatriz Carvalho; Sofia Friães; Catarina Roma-Rodrigues; Jhonathan A. A. Fernández; Sabela F. Vila; et al. "Triazole-Based Half-Sandwich Ruthenium(II) Compounds: From In Vitro Antiproliferative Potential to In Vivo Toxicity Evaluation". Inorganic Chemistry 60 11 (2021): 8011-8026. https://doi.org/10.1021/acs.inorgchem.1c00527.
    10.1021/acs.inorgchem.1c00527
  10. Margarida Ferreira-Silva; Catarina Faria-Silva; Pedro Viana Baptista; Eduarda Fernandes; Alexandra Ramos Fernandes; Maria Luísa Corvo. "Drug delivery nanosystems targeted to hepatic ischemia and reperfusion injury". Drug Delivery and Translational Research (2021): https://doi.org/10.1007/s13346-021-00915-8.
    10.1007/s13346-021-00915-8
  11. Margarida Ferreira-Silva; Catarina Faria-Silva; Pedro Viana Baptista; Eduarda Fernandes; Alexandra Ramos Fernandes; Maria Luísa Corvo. "Liposomal Nanosystems in Rheumatoid Arthritis". Pharmaceutics 13 4 (2021): 454-454. https://doi.org/10.3390/pharmaceutics13040454.
    10.3390/pharmaceutics13040454
  12. Francisco Reigosa-Chamorro; Luís R. Raposo; Paula Munín-Cruz; M. Teresa Pereira; Catarina Roma-Rodrigues; Pedro V. Baptista; Alexandra R. Fernandes; José M. Vila. "In Vitro and In Vivo Effect of Palladacycles: Targeting A2780 Ovarian Carcinoma Cells and Modulation of Angiogenesis". Inorganic Chemistry (2021): https://doi.org/10.1021/acs.inorgchem.0c03763.
    10.1021/acs.inorgchem.0c03763
  13. Oscar A. Lenis-Rojas; M. Paula Robalo; Ana Isabel Tomaz; Alexandra R. Fernandes; Catarina Roma-Rodrigues; Ricardo G. Teixeira; Fernanda Marques; et al. "Half-Sandwich Ru(p-cymene) Compounds with Diphosphanes: In Vitro and In Vivo Evaluation As Potential Anticancer Metallodrugs". Inorganic Chemistry (2021): https://doi.org/10.1021/acs.inorgchem.0c02768.
    10.1021/acs.inorgchem.0c02768
  14. Choroba, Katarzyna; Machura, Barbara; Szlapa-Kula, Agata; Malecki, Jan G.; Raposo, Luis; Roma-Rodrigues, Catarina; Cordeiro, Sandra; Baptista, Pedro V.; Fernandes, Alexandra R.. "Square planar Au(III), Pt(II) and Cu(II) complexes with quinoline-substituted 2,2':6',2''-terpyridine ligands: from in vitro to in vivo biological properties". European Journal of Medicinal Chemistry (2021): 113404. http://dx.doi.org/10.1016/j.ejmech.2021.113404.
    10.1016/j.ejmech.2021.113404
  15. José L. Quiles; Catarina Roma-Rodrigues; Luís R Raposo; María D. Navarro-Hortal; Jose M. Romero-Márquez; Adelaida Esteban-Muñoz; Alfonso Varela-López; et al. "Rosa x hybrida extracts with dual actions: Antiproliferative effects against tumour cells and inhibitor of Alzheimer disease". Food and Chemical Toxicology 149 (2021): https://novaresearch.unl.pt/en/publications/1dd08105-b75e-4004-aff7-1afa1ee9e732.
    10.1016/j.fct.2021.112018
  16. Ana P. Rodrigo; Ana R. Grosso; Pedro V. Baptista; Alexandra R. Fernandes; Pedro M. Costa. "A Transcriptomic Approach to the Recruitment of Venom Proteins in a Marine Annelid". Toxins 13 2 (2021): 97-97. https://doi.org/10.3390/toxins13020097.
    10.3390/toxins13020097
  17. Ana P. Rodrigo; Vera M. Mendes; Bruno Manadas; Ana R. Grosso; António P. Alves de Matos; Pedro V. Baptista; Pedro M. Costa; Alexandra R. Fernandes. "Specific Antiproliferative Properties of Proteinaceous Toxin Secretions from the Marine Annelid Eulalia sp. onto Ovarian Cancer Cells". Marine Drugs (2021): https://doi.org/10.3390/md19010031.
    10.3390/md19010031
  18. Luís R. Raposo; Ana Silva; Dário Silva; Catarina Roma-Rodrigues; Margarida Espadinha; Pedro V. Baptista; Maria M.M. Santos; Alexandra R. Fernandes. "Exploiting the antiproliferative potential of spiropyrazoline oxindoles in a human ovarian cancer cell line". Bioorganic & Medicinal Chemistry 30 (2021): 115880-115880. https://doi.org/10.1016/j.bmc.2020.115880.
    10.1016/j.bmc.2020.115880
  19. Pedro Pedrosa; Pedro V. Baptista; Alexandra R. Fernandes; Mauro Guerra. "Benchtop X-ray fluorescence imaging as a tool to study gold nanoparticle penetration in 3D cancer spheroids". RSC Advances (2021): https://doi.org/10.1039/D1RA05446E.
    10.1039/D1RA05446E
  20. Nazanin Kordestani; Hadi Amiri Rudbari; Alexandra R. Fernandes; Luís R. Raposo; André Luz; Pedro V. Baptista; Giuseppe Bruno; et al. "Copper(ii) complexes with tridentate halogen-substituted Schiff base ligands: synthesis, crystal structures and investigating the effect of halogenation, leaving groups and ligand flexibility on antiproliferative activities". Dalton Transactions (2021): https://doi.org/10.1039/D0DT03962D.
    10.1039/D0DT03962D
  21. Diogo Sequeira; Pedro V. Baptista; Ruben Valente; M. Fátima M. Piedade; M. Helena Garcia; Tânia S. Morais; Alexandra R. Fernandes. "Cu(i) complexes as new antiproliferative agents against sensitive and doxorubicin resistant colorectal cancer cells: synthesis, characterization, and mechanisms of action". Dalton Transactions (2021): https://doi.org/10.1039/D0DT03566A.
    10.1039/D0DT03566A
  22. Catarina Roma-Rodrigues; Inês Pombo; Alexandra R. Fernandes; Pedro V. Baptista. "Hyperthermia Induced by Gold Nanoparticles and Visible Light Photothermy Combined with Chemotherapy to Tackle Doxorubicin Sensitive and Resistant Colorectal Tumor 3D Spheroids". International Journal of Molecular Sciences 21 21 (2020): 8017-8017. https://doi.org/10.3390/ijms21218017.
    10.3390/ijms21218017
  23. Lilianne Beola; Laura Asín; Catarina Roma-Rodrigues; Yilian Fernandez-Afonso; Raluca M. Fratila; David Serantes; Sergiu Ruta; et al. "The intracellular number of magnetic nanoparticles modulates the apoptotic death pathway after magnetic hyperthermia treatment". ACS Applied Materials and Interfaces 12 39 (2020): 43474-43487. https://novaresearch.unl.pt/en/publications/58ee5e02-b4e8-4d36-a618-a3d36901a6a7.
    10.1021/acsami.0c12900
  24. Daniela Ferreira; David Fontinha; Catarina Martins; David Pires; Alexandra R. Fernandes; Pedro V. Baptista. "Gold Nanoparticles for Vectorization of Nucleic Acids for Cancer Therapeutics". Molecules (2020): https://doi.org/10.3390/molecules25153489.
    10.3390/molecules25153489
  25. Daniela Alves Ferreira; Luísa M. D. R. S. Martins; Alexandra R. Fernandes; Marta Martins. "A Tale of Two Ends: Repurposing Metallic Compounds from Anti-Tumour Agents to Effective Antibacterial Activity". Antibiotics 9 6 (2020): 321-321. https://doi.org/10.3390/antibiotics9060321.
    10.3390/antibiotics9060321
  26. Rita B. Restani; Rita F. Pires; Pedro V. Baptista; Alexandra R. Fernandes; Teresa Casimiro; Vasco D. B. Bonifácio; Ana Aguiar-Ricardo. "Nano-in-Micro Sildenafil Dry Powder Formulations for the Treatment of Pulmonary Arterial Hypertension Disorders: The Synergic Effect of POxylated Polyurea Dendrimers, PLGA, and Cholesterol". Particle & Particle Systems Characterization (2020): 1900447-1900447. https://doi.org/10.1002/ppsc.201900447.
    10.1002/ppsc.201900447
  27. Beatriz Oliveira; Bruno Veigas; Alexandra R. Fernandes; Hugo Águas; Rodrigo Martins; Elvira Fortunato; Pedro Viana Baptista. "Fast Prototyping Microfluidics: Integrating Droplet Digital Lamp for Absolute Quantification of Cancer Biomarkers". Sensors (2020): https://doi.org/10.3390/s20061624.
    10.3390/s20061624
  28. Roma-Rodrigues, Catarina; Rivas-García, Lorenzo; Baptista, Pedro V.; Fernandes, Alexandra R.. "Gene Therapy in Cancer Treatment: Why Go Nano?". Pharmaceutics 12 3 (2020): 233. http://dx.doi.org/10.3390/pharmaceutics12030233.
    10.3390/pharmaceutics12030233
  29. Nazanin Kordestani; Hadi Amiri Rudbari; Alexandra R. Fernandes; Luís R. Raposo; Pedro V. Baptista; Daniela Ferreira; Giuseppe Bruno; et al. "Antiproliferative Activities of Diimine-Based Mixed Ligand Copper(II) Complexes". ACS Combinatorial Science 22 2 (2020): 89-99. https://doi.org/10.1021/acscombsci.9b00202.
    10.1021/acscombsci.9b00202
  30. Katarzyna Choroba; Luis R. Raposo; Joanna Palion-Gazda; Ewa Malicka; Karol Erfurt; Barbara Machura; Alexandra R. Fernandes. "In vitro antiproliferative effect of vanadium complexes bearing 8-hydroxyquinoline-based ligands – the substituent effect". Dalton Transactions (2020): https://doi.org/10.1039/D0DT01017K.
    10.1039/D0DT01017K
  31. Fernandes, A.R.; Mendonça-Martins, I.; Santos, M.F.A.; Raposo, L.R.; Mendes, R.; Marques, J.; Romão, C.C.; et al. "Improving the Anti-inflammatory Response via Gold Nanoparticle Vectorization of CO-Releasing Molecules". ACS Biomaterials Science and Engineering 6 2 (2020): 1090-1101. http://www.scopus.com/inward/record.url?eid=2-s2.0-85079071744&partnerID=MN8TOARS.
    10.1021/acsbiomaterials.9b01936
  32. Busila, M.; Tabacaru, A.; Mussat, V.; Vasile, B.S.; Neasu, I.A.; Pinheiro, T.; Roma-Rodrigues, C.; et al. "Size-Dependent Biological Activities of Fluorescent Organosilane-Modified Zinc Oxide Nanoparticles". Journal of biomedical nanotechnology 16 2 (2020): 137-152. http://www.scopus.com/inward/record.url?eid=2-s2.0-85083071724&partnerID=MN8TOARS.
    10.1166/jbn.2020.2882
  33. Roma-Rodrigues, C.; Malta, G.; Peixoto, D.; Ferreira, L.M.; Baptista, P.V.; Fernandes, A.R.; Branco, P.S.. "Synthesis of new hetero-arylidene-9(10H)-anthrone derivatives and their biological evaluation". Bioorganic Chemistry 99 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85083360964&partnerID=MN8TOARS.
    10.1016/j.bioorg.2020.103849
  34. João Franco Machado; Diogo Sequeira; Fernanda Marques; M. Fátima M. Piedade; Maria J. Villa de Brito; M. Helena Garcia; Alexandra R. Fernandes; Tânia S. Morais. "New copper(i) complexes selective for prostate cancer cells". Dalton Transactions (2020): https://doi.org/10.1039/D0DT02157A.
    10.1039/D0DT02157A
  35. Pedro Pedrosa; M. Luísa Corvo; Margarida Ferreira-Silva; Pedro Martins; Manuela Colla Carvalheiro; Pedro M. Costa; Carla Martins; et al. "Targeting Cancer Resistance via Multifunctional Gold Nanoparticles". International Journal of Molecular Sciences (2019): https://doi.org/10.3390/ijms20215510.
    10.3390/ijms20215510
  36. Das K; Datta A; Frontera A; Wen YS; Roma-Rodrigues C; Raposo LR; Fernandes AR; Hung CH. "Zn(II) and Co(II) derivatives anchored with scorpionate precursor: Antiproliferative evaluation in human cancer cell lines.". Journal of inorganic biochemistry (2019): http://europepmc.org/abstract/med/31698185.
    10.1016/j.jinorgbio.2019.110881
  37. Catarina Roma-Rodrigues; Alexandra R. Fernandes; Pedro V. Baptista. "

    Counteracting the effect of leukemia exosomes by antiangiogenic gold nanoparticles

    ". International Journal of Nanomedicine (2019): https://doi.org/10.2147/IJN.S215711.
    10.2147/IJN.S215711
  38. Roma-Rodrigues C; Pombo I; Raposo L; Pedrosa P; Fernandes AR; Baptista PV. "Nanotheranostics Targeting the Tumor Microenvironment.". Frontiers in bioengineering and biotechnology (2019): http://europepmc.org/abstract/med/31475143.
    10.3389/fbioe.2019.00197
  39. Almeida J; Roma-Rodrigues C; Mahmoud AG; Guedes da Silva MFC; Pombeiro AJL; Martins LMDRS; Baptista PV; Fernandes AR. "Structural characterization and biological properties of silver(I) tris(pyrazolyl)methane sulfonate.". Journal of inorganic biochemistry (2019): http://europepmc.org/abstract/med/31357066.
    10.1016/j.jinorgbio.2019.110789
  40. Veigas B; Matias A; Calmeiro T; Fortunato E; Fernandes AR; Baptista PV. "Antibody modified gold nanoparticles for fast colorimetric screening of rheumatoid arthritis.". The Analyst (2019): http://europepmc.org/abstract/med/31070614.
    10.1039/c9an00319c
  41. Santos MM; Raposo LR; Carrera GVSM; Costa A; Dionísio M; Baptista PV; Fernandes AR; Branco LC. "Ionic Liquids and Salts from Ibuprofen as Promising Innovative Formulations of an Old Drug.". ChemMedChem (2019): http://europepmc.org/abstract/med/30735308.
    10.1002/cmdc.201900040
  42. Jesus AR; Soromenho MRC; Raposo LR; Esperança JMSS; Baptista PV; Fernandes AR; Reis PM. "Enhancement of water solubility of poorly water-soluble drugs by new biocompatible N-acetyl amino acid N-alkyl cholinium-based ionic liquids.". European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V (2019): http://europepmc.org/abstract/med/30836180.
    10.1016/j.ejpb.2019.03.004
  43. Catarina Roma-Rodrigues; Rita Mendes; P. V. Baptista; Alexandra Fernandes. "Targeting Tumor Microenvironment for Cancer Therapy". International Journal of Molecular Sciences (2019): http://www.mdpi.com/1422-0067/20/4/840.
    10.3390/ijms20040840
  44. Alves-Barroco C; Roma-Rodrigues C; Balasubramanian N; Guimarães MA; Ferreira-Carvalho BT; Muthukumaran J; Nunes D; et al. "Biofilm development and computational screening for new putative inhibitors of a homolog of the regulatory protein BrpA in Streptococcus dysgalactiae subsp. dysgalactiae.". International journal of medical microbiology : IJMM (2019): http://europepmc.org/abstract/med/30799091.
    10.1016/j.ijmm.2019.02.001
  45. Kourmentza C; Araujo D; Sevrin C; Roma-Rodriques C; Lia Ferreira J; Freitas F; Dionisio M; et al. "Occurrence of non-toxic bioemulsifiers during polyhydroxyalkanoate production by Pseudomonas strains valorizing crude glycerol by-product.". Bioresource technology (2019): http://europepmc.org/abstract/med/30798087.
    10.1016/j.biortech.2019.02.066
  46. Cinthia Alves-Barroco; Catarina Roma-Rodrigues; Luís R. Raposo; Catarina Brás; Mário Diniz; João Caço; Pedro M. Costa; et al. "Streptococcus dysgalactiae subsp. dysgalactiae isolated from milk of the bovine udder as emerging pathogens: In vitro and in vivo infection of human cells and zebrafish as biological models". MicrobiologyOpen 8 1 (2019): e00623-e00623. https://doi.org/10.1002/mbo3.623.
    10.1002/mbo3.623
  47. Oliveira H; Roma-Rodrigues C; Santos A; Veigas B; Brás N; Faria A; Calhau C; et al. "GLUT1 and GLUT3 involvement in anthocyanin gastric transport- Nanobased targeted approach.". Scientific reports (2019): http://europepmc.org/abstract/med/30692585.
    10.1038/s41598-018-37283-2
  48. Fialho, Letícia; Araújo, Diana; Alves, Vitor D.; Roma-Rodrigues, Catarina; Baptista, Pedro V.; Fernandes, Alexandra R.; Freitas, Filomena; et al. "Cation-mediated gelation of the fucose-rich polysaccharide FucoPol: preparation and characterization of hydrogel beads and their cytotoxicity assessment". (2019): http://hdl.handle.net/10362/93177.
    https://doi.org/10.1080/00914037.2019.1695205
  49. Sutradhar, Manas; Alegria, Elisabete; Ferretti, Francesco; Raposo, Luís R; Guedes Da Silva, M. Fátima C.; Baptista, Pedro; Fernandes, Alexandra; Pombeiro, Armando. "Antiproliferative activity of heterometallic sodium and potassium-dioxidovanadium(V) polymers". (2019): http://hdl.handle.net/10400.21/10589.
    10.1016/j.jinorgbio.2019.110811
  50. Catarina Bravo; M. Paula Robalo; Fernanda Marques; Alexandra R. Fernandes; Diogo A. Sequeira; M. Fátima M. Piedade; M. Helena Garcia; Maria J. Villa de Brito; Tânia S. Morais. "First heterobimetallic Cu(i)–dppf complexes designed for anticancer applications: synthesis, structural characterization and cytotoxicity". New Journal of Chemistry (2019): https://doi.org/10.1039/C9NJ02068C.
    10.1039/C9NJ02068C
  51. Katarzyna Choroba; Barbara Machura; Slawomir Kula; Luis R. Raposo; Alexandra R. Fernandes; Rafal Kruszynski; Karol Erfurt; et al. "Copper(ii) complexes with 2,2':6',2''-terpyridine, 2,6-di(thiazol-2-yl)pyridine and 2,6-di(pyrazin-2-yl)pyridine substituted with quinolines. Synthesis, structure, antiproliferative activity, and catalytic activity in the oxidation of alkanes and alcohols with peroxides". Dalton Transactions (2019): https://doi.org/10.1039/C9DT01922G.
    10.1039/C9DT01922G
  52. Katarzyna Choroba; Barbara Machura; Luis R. Raposo; Jan G. Malecki; Slawomir Kula; Michal Pajak; Karol Erfurt; Anna M. Maron; Alexandra R. Fernandes. "Platinum(ii) complexes showing high cytotoxicity toward A2780 ovarian carcinoma cells". Dalton Transactions (2019): https://doi.org/10.1039/C9DT02894C.
    10.1039/C9DT02894C
  53. Das, K.; Datta, A.; Massera, C.; Roma-Rodrigues, C.; Barroso, M.; Baptista, P.V.; Fernandes, A.R.. "Structural aspects of a trimetallic Cu II derivative: cytotoxicity and anti-proliferative activity on human cancer cell lines". Journal of Coordination Chemistry 72 5-7 (2019): 920-940. http://www.scopus.com/inward/record.url?eid=2-s2.0-85065565968&partnerID=MN8TOARS.
    10.1080/00958972.2019.1597973
  54. Raquel Vinhas; Alexandra Lourenço; Susana Santos; Marcos Lemos; Patrícia Ribeiro; Aida Botelho de Sousa; Pedro V. Baptista; Alexandra R. Fernandes. "A novel BCR-ABL1 mutation in a patient with Philadelphia chromosome-positive B-cell acute lymphoblastic leukemia". OncoTargets and Therapy (2018): https://doi.org/10.2147/OTT.S177019.
    10.2147/OTT.S177019
  55. Rita B. Restani; Rita F. Pires; Anna Tolmatcheva; Rita Cabral; Pedro V. Baptista; Alexandra R. Fernandes; Teresa Casimiro; et al. "POxylated Dendrimer-Based Nano-in-Micro Dry Powder Formulations for Inhalation Chemotherapy". ChemistryOpen 7 10 (2018): 772-779. https://doi.org/10.1002/open.201800093.
    10.1002/open.201800093
  56. Rita B. Restani; Rita F. Pires; Anna Tolmatcheva; Rita Cabral; Pedro V. Baptista; Alexandra R. Fernandes; Teresa Casimiro; Vasco D. B. Bonifácio; Ana Aguiar-Ricardo. "Cover Feature: POxylated Dendrimer-Based Nano-in-Micro Dry Powder Formulations for Inhalation Chemotherapy (ChemistryOpen 10/2018)". ChemistryOpen 7 10 (2018): 751-751. https://doi.org/10.1002/open.201800165.
    10.1002/open.201800165
  57. Noora Svahn; Artur J. Moro; Catarina Roma-Rodrigues; Rakesh Puttreddy; Kari Rissanen; Pedro V. Baptista; Alexandra R. Fernandes; João Carlos Lima; Laura Rodríguez. "Front Cover: The Important Role of the Nuclearity, Rigidity, and Solubility of Phosphane Ligands in the Biological Activity of Gold(I) Complexes (Chem. Eur. J. 55/2018)". Chemistry - A European Journal (2018): https://doi.org/10.1002/chem.201804177.
    10.1002/chem.201804177
  58. Sutradhar M; Fernandes AR; Paradinha F; Rijo P; Garcia C; Roma-Rodrigues C; Pombeiro AJL; Charmier AJ. "A new Cu(II)-O-Carvacrotinate complex: Synthesis, characterization and biological activity.". Journal of inorganic biochemistry (2018): http://europepmc.org/abstract/med/30342353.
    10.1016/j.jinorgbio.2018.09.018
  59. Vinhas R; Lourenço A; Santos S; Ribeiro P; Silva M; de Sousa AB; Baptista PV; Fernandes AR. "A double Philadelphia chromosome-positive chronic myeloid leukemia patient, co-expressing P210BCR-ABL1 and P195BCR-ABL1 isoforms.". Haematologica (2018): http://europepmc.org/abstract/med/30093395.
    10.3324/haematol.2018.192534
  60. Ribeiro, A. P. C.; Anbu, S.; Alegria, Elisabete; Fernandes, Alexandra; Baptista, Pedro; Mendes, R.; Matias, A. S.; et al. "Evaluation of cell toxicity and DNA and protein binding of green synthesized silver nanoparticles". (2018): http://hdl.handle.net/10400.21/9121.
    10.1016/j.biopha.2018.02.069
  61. Pedrosa, Pedro; Mendes, Rita; Cabral, Rita; Martins, Luísa M. D. R. S.; Baptista, Pedro V.; Fernandes, Alexandra R.; DCV - Departamento de Ciências da Vida; et al. "Combination of chemotherapy and Au-nanoparticle photothermy in the visible light to tackle doxorubicin resistance in cancer cells". Scientific Reports 8 1 (2018): http://www.scopus.com/inward/record.url?scp=85050817470&partnerID=8YFLogxK.
    https://doi.org/10.1038/s41598-018-29870-0
  62. Lenis-Rojas, Oscar A.; Robalo, Maria Paula; Tomaz, Ana Isabel; Carvalho, Andreia; Fernandes, Alexandra R.; Marques, Fernanda; Folgueira, Mónica; et al. "Ru-II(p-cymene) compounds as effective and selective anticancer candidates with no toxicity in vivo". (2018): http://hdl.handle.net/10400.21/8964.
    10.1021/acs.inorgchem.8b01270
  63. Gomes, S.E.; Pereira, D.M.; Roma-Rodrigues, C.; Fernandes, A.R.; Borralho, P.M.; Rodrigues, C.M.P.. "Convergence of MIR-143 overexpression, oxidative stress and cell death in HCT116 human colon cancer cells". PLoS ONE 13 1 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85040986423&partnerID=MN8TOARS.
    10.1371/journal.pone.0191607
  64. Baptista, P.V.; McCusker, M.P.; Carvalho, A.; Ferreira, D.A.; Mohan, N.M.; Martins, M.; Fernandes, A.R.; et al. "Nano-strategies to fight multidrug resistant bacteria-"A Battle of the Titans"". Frontiers in Microbiology 9 JUL (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85049384316&partnerID=MN8TOARS.
    10.3389/fmicb.2018.01441
  65. Subhabrata Sen; Chandramohan Bathula; Catarina Rodrigues; Alexandra Fernandes; Jyoti Chauhan. "Synthesis of tetrahydro-1H-indolo[2, 3-b]pyrrolo[3, 2-c]quinolones via intramolecular oxidative ring rearrangement of tetrahydro-ß-carbolines and their biological evaluation". New Journal of Chemistry (2018): https://doi.org/10.1039%2Fc7nj04616b.
    10.1039/c7nj04616b
  66. Alves, P. U.; Vinhas, R.; Fernandes, A. R.; Birol, S. Z.; Trabzon, L.; Bernacka-Wojcik, I.; Igreja, R.; et al. "Multifunctional microfluidic chip for optical nanoprobe based RNA detection - application to Chronic Myeloid Leukemia". Sci Rep 8 1 (2018): 381-381. https://www.ncbi.nlm.nih.gov/pubmed/29321602.
    10.1038/s41598-017-18725-9
  67. Svahn, N.; Moro, A.J.; Roma-Rodrigues, C.; Puttreddy, R.; Rissanen, K.; Baptista, P.V.; Fernandes, A.R.; Lima, J.C.; Rodríguez, L.. "The Important Role of the Nuclearity, Rigidity, and Solubility of Phosphane Ligands in the Biological Activity of Gold(I) Complexes". Chemistry (Weinheim an der Bergstrasse, Germany) 24 55 (2018): 14654-14667. http://www.scopus.com/inward/record.url?eid=2-s2.0-85054065949&partnerID=MN8TOARS.
    10.1002/chem.201804176
  68. Maron, A.; Czerwinska, K.; Machura, B.; Raposo, L.; Roma-Rodrigues, C.; Fernandes, A.R.; Malecki, J.G.; et al. "Spectroscopy, electrochemistry and antiproliferative properties of Au(iii), Pt(ii) and Cu(ii) complexes bearing modified 2,2':6',2''-terpyridine ligands". Dalton Transactions 47 18 (2018): 6444-6463. http://www.scopus.com/inward/record.url?eid=2-s2.0-85046839407&partnerID=MN8TOARS.
    10.1039/c8dt00558c
  69. Peixoto, D.; Figueiredo, M.; Malta, G.; Roma-Rodrigues, C.; Baptista, P.V.; Fernandes, A.R.; Barroso, S.; et al. "Synthesis, Cytotoxicity Evaluation in Human Cell Lines and in Vitro DNA Interaction of a Hetero-Arylidene-9(10H)-Anthrone". European Journal of Organic Chemistry 2018 4 (2018): 545-549. http://www.scopus.com/inward/record.url?eid=2-s2.0-85041287294&partnerID=MN8TOARS.
    10.1002/ejoc.201701500
  70. Morais, T.S.; Jousseaume, Y.; Piedade, M.F.M.; Roma-Rodrigues, C.; Fernandes, A.R.; Marques, F.; Villa De Brito, M.J.; Helena Garcia, M.. "Important cytotoxic and cytostatic effects of new copper(i)-phosphane compounds with N,N, N,O and N,S bidentate ligands". Dalton Transactions 47 23 (2018): 7819-7829. http://www.scopus.com/inward/record.url?eid=2-s2.0-85048401535&partnerID=MN8TOARS.
    10.1039/c8dt01653d
  71. Das, K.; Beyene, B.B.; Datta, A.; Garribba, E.; Roma-Rodrigues, C.; Silva, A.; Fernandes, A.R.; Hung, C.-H.. "EPR and electrochemical interpretation of bispyrazolylacetate anchored Ni(ii) and Mn(ii) complexes: Cytotoxicity and anti-proliferative activity towards human cancer cell lines". New Journal of Chemistry 42 11 (2018): 9126-9139. http://www.scopus.com/inward/record.url?eid=2-s2.0-85047986859&partnerID=MN8TOARS.
    10.1039/c8nj01033a
  72. Fernandes, A.R.; Jesus, J.; Martins, P.; Figueiredo, S.; Rosa, D.; Martins, L.M.R.D.R.S.; Corvo, M.L.; et al. "Multifunctional gold-nanoparticles: A nanovectorization tool for the targeted delivery of novel chemotherapeutic agents". Journal of Controlled Release 245 (2017): 52-61. http://www.scopus.com/inward/record.url?eid=2-s2.0-84999008906&partnerID=MN8TOARS.
    10.1016/j.jconrel.2016.11.021
  73. Lenis-Rojas, O.A.; Roma-Rodrigues, C.; Fernandes, A.R.; Marques, F.; Pérez-Fernández, D.; Guerra-Varela, J.; Sánchez, L.; et al. "Dinuclear RuII(bipy)2Derivatives: Structural, Biological, and in Vivo Zebrafish Toxicity Evaluation". Inorganic Chemistry 56 12 (2017): 7127-7144. http://www.scopus.com/inward/record.url?eid=2-s2.0-85020908951&partnerID=MN8TOARS.
    10.1021/acs.inorgchem.7b00790
  74. Tavares, M.; Cabral, R.P.; Costa, C.; Martins, P.; Fernandes, A.R.; Casimiro, T.; Aguiar-Ricardo, A.. "Development of PLGA dry powder microparticles by supercritical CO2-assisted spray-drying for potential vaccine delivery to the lungs". Journal of Supercritical Fluids 128 (2017): 235-243. http://www.scopus.com/inward/record.url?eid=2-s2.0-85020706929&partnerID=MN8TOARS.
    10.1016/j.supflu.2017.06.004
  75. Raposo, L.R.; Roma-Rodrigues, C.; Jesus, J.; Martins, L.M.D.R.S.; Pombeiro, A.J.; Baptista, P.V.; Fernandes, A.R.. "Targeting canine mammary tumours via gold nanoparticles functionalized with promising Co(II) and Zn(II) compounds". Veterinary and Comparative Oncology (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85011706279&partnerID=MN8TOARS.
    10.1111/vco.12298
  76. Sutradhar, M.; Rajeshwari; Roy Barman, T.; Fernandes, A.R.; Paradinha, F.; Roma-Rodrigues, C.; Guedes da Silva, M.F.C.; Pombeiro, A.J.L.. "Mixed ligand aroylhydrazone and N-donor heterocyclic Lewis base Cu(II) complexes as potential antiproliferative agents". Journal of Inorganic Biochemistry 175 (2017): 267-275. http://www.scopus.com/inward/record.url?eid=2-s2.0-85028731781&partnerID=MN8TOARS.
    10.1016/j.jinorgbio.2017.07.034
  77. Roma-Rodrigues, C.; Raposo, L.R.; Cabral, R.; Paradinha, F.; Baptista, P.V.; Fernandes, A.R.. "Tumor microenvironment modulation via gold nanoparticles targeting malicious exosomes: Implications for cancer diagnostics and therapy". International Journal of Molecular Sciences 18 1 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85009892134&partnerID=MN8TOARS.
    10.3390/ijms18010162
  78. Vinhas, R.; Cordeiro, M.; Pedrosa, P.; Fernandes, A.R.; Baptista, P.V.. "Current trends in molecular diagnostics of chronic myeloid leukemia". Leukemia and Lymphoma 58 8 (2017): 1791-1804. http://www.scopus.com/inward/record.url?eid=2-s2.0-85002410324&partnerID=MN8TOARS.
    10.1080/10428194.2016.1265116
  79. do Nascimento-Neto, L. G.; Cabral, M. G.; Carneiro, R. F.; Silva, Z.; Arruda, F. V. S.; Nagano, C. S.; Fernandes, A. R.; et al. "Halilectin-3, a lectin from the marine sponge Haliclona caerulea, induces apoptosis and autophagy in human breast cancer MCF7 cells through caspase-9 pathway and LC3-II protein expression". Anticancer Agents Med Chem (2017): https://www.ncbi.nlm.nih.gov/pubmed/29141557.
    10.2174/1871520617666171114094847
  80. Cordeiro, M.; Carvalho, L.; Silva, J.; Saúde, L.; Fernandes, A.R.; Baptista, P.V.. "Gold nanobeacons for tracking gene silencing in zebrafish". Nanomaterials 7 1 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85009776467&partnerID=MN8TOARS.
    10.3390/nano7010010
  81. Vinhas, R.; Fernandes, A.R.; Baptista, P.V.. "Gold Nanoparticles for BCR-ABL1 Gene Silencing: Improving Tyrosine Kinase Inhibitor Efficacy in Chronic Myeloid Leukemia". Molecular Therapy - Nucleic Acids 7 (2017): 408-416. http://www.scopus.com/inward/record.url?eid=2-s2.0-85020493223&partnerID=MN8TOARS.
    10.1016/j.omtn.2017.05.003
  82. Roma-Rodrigues, C.; Pereira, F.; Alves de Matos, A.P.; Fernandes, M.; Baptista, P.V.; Fernandes, A.R.. "Smuggling gold nanoparticles across cell types – A new role for exosomes in gene silencing". Nanomedicine: Nanotechnology, Biology, and Medicine 13 4 (2017): 1389-1398. http://www.scopus.com/inward/record.url?eid=2-s2.0-85016940939&partnerID=MN8TOARS.
    10.1016/j.nano.2017.01.013
  83. Sousa, J.R.; Silveira, C.M.; Fontes, P.; Roma-Rodrigues, C.; Fernandes, A.R.; Van Driessche, G.; Devreese, B.; et al. "Understanding the response of Desulfovibrio desulfuricans ATCC 27774 to the electron acceptors nitrate and sulfate - biosynthetic costs modulate substrate selection". Biochimica et Biophysica Acta - Proteins and Proteomics 1865 11 (2017): 1455-1469. http://www.scopus.com/inward/record.url?eid=2-s2.0-85029543107&partnerID=MN8TOARS.
    10.1016/j.bbapap.2017.07.021
  84. Mendes, R.; Pedrosa, P.; Lima, J.C.; Fernandes, A.R.; Baptista, P.V.. "Photothermal enhancement of chemotherapy in breast cancer by visible irradiation of Gold Nanoparticles". Scientific Reports 7 1 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85029131135&partnerID=MN8TOARS.
    10.1038/s41598-017-11491-8
  85. Mendes, R.; Fernandes, A.R.; Baptista, P.V.. "Gold nanoparticle approach to the selective delivery of gene silencing in cancer-The case for combined delivery?". Genes 8 3 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85014580813&partnerID=MN8TOARS.
    10.3390/genes8030094
  86. Czerwinska, K.; Machura, B.; Kula, S.; Krompiec, S.; Erfurt, K.; Roma-Rodrigues, C.; Fernandes, A.R.; et al. "Copper(II) complexes of functionalized 2,2':6',2''-terpyridines and 2,6-di(thiazol-2-yl)pyridine: Structure, spectroscopy, cytotoxicity and catalytic activity". Dalton Transactions 46 29 (2017): 9591-9604. http://www.scopus.com/inward/record.url?eid=2-s2.0-85026482321&partnerID=MN8TOARS.
    10.1039/c7dt01244f
  87. Vinhas, R.; Mendes, R.; Fernandes, A.R.; Baptista, P.V.. "Nanoparticles-Emerging potential for managing leukemia and lymphoma". Frontiers in Bioengineering and Biotechnology 5 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85042668888&partnerID=MN8TOARS.
    10.3389/fbioe.2017.00079
  88. Raposo, L.R.; Roma-Rodrigues, C.; Faísca, P.; Alves, M.; Henriques, J.; Carvalheiro, M.C.; Corvo, M.L.; et al. "Immortalization and characterization of a new canine mammary tumour cell line FR37-CMT". Veterinary and Comparative Oncology 15 3 (2017): 952-967. http://www.scopus.com/inward/record.url?eid=2-s2.0-84964950972&partnerID=MN8TOARS.
    10.1111/vco.12235
  89. Pedrosa, P.; Heuer-Jungemann, A.; Kanaras, A.G.; Fernandes, A.R.; Baptista, P.V.. "Potentiating angiogenesis arrest in vivo via laser irradiation of peptide functionalised gold nanoparticles". Journal of Nanobiotechnology 15 1 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85034650247&partnerID=MN8TOARS.
    10.1186/s12951-017-0321-2
  90. Lenis-Rojas, O.A.; Fernandes, A.R.; Roma-Rodrigues, C.; Baptista, P.V.; Marques, F.; Pérez-Fernández, D.; Guerra-Varela, J.; et al. "Heteroleptic mononuclear compounds of ruthenium(II): Synthesis, structural analyses,: In vitro antitumor activity and in vivo toxicity on zebrafish embryos". Dalton Transactions 45 47 (2016): 19127-19140. http://www.scopus.com/inward/record.url?eid=2-s2.0-85000786901&partnerID=MN8TOARS.
    10.1039/c6dt03591d
  91. Palma, S.I.C.J.; Fernandes, A.R.; Roque, A.C.A.. "An affinity triggered MRI nanoprobe for pH-dependent cell labeling". RSC Advances 6 114 (2016): 113503-113512. http://www.scopus.com/inward/record.url?eid=2-s2.0-85002152535&partnerID=MN8TOARS.
    10.1039/C6RA17217B
  92. Mendes, R.; Carreira, B.; Baptista, P.V.; Fernandes, A.R.. "Non-small cell lung cancer biomarkers and targeted therapy - two faces of the same coin fostered by nanotechnology". Expert Review of Precision Medicine and Drug Development 1 2 (2016): 155-168. http://www.scopus.com/inward/record.url?eid=2-s2.0-84998713466&partnerID=MN8TOARS.
    10.1080/23808993.2016.1159914
  93. Silva, M.; Silva, Z.; Marques, G.; Ferro, T.; Gonçalves, M.; Monteiro, M.; van Vliet, S.J.; et al. "Sialic acid removal from dendritic cells improves antigen cross-presentation and boosts anti-tumor immune responses". Oncotarget 7 27 (2016): 41053-41066. http://www.scopus.com/inward/record.url?eid=2-s2.0-85014489244&partnerID=MN8TOARS.
    10.18632/oncotarget.9419
  94. Roma-Rodrigues, C.; Alves-Barroco, C.; Raposo, L.R.; Costa, M.N.; Fortunato, E.; Baptista, P.V.; Fernandes, A.R.; Santos-Sanches, I.. "Infection of human keratinocytes by Streptococcus dysgalactiae subspecies dysgalactiae isolated from milk of the bovine udder". Microbes and Infection 18 4 (2016): 290-293. http://www.scopus.com/inward/record.url?eid=2-s2.0-84962050500&partnerID=MN8TOARS.
    10.1016/j.micinf.2015.11.005
  95. Vinhas, R.; Correia, C.; Ribeiro, P.; Lourenço, A.; Botelho de Sousa, A.; Fernandes, A.R.; Baptista, P.V.. "Colorimetric assessment of BCR-ABL1 transcripts in clinical samples via gold nanoprobes". Analytical and Bioanalytical Chemistry 408 19 (2016): 5277-5284. http://www.scopus.com/inward/record.url?eid=2-s2.0-84969988700&partnerID=MN8TOARS.
    10.1007/s00216-016-9622-9
  96. Corvo, M.L.; Mendo, A.S.; Figueiredo, S.; Gaspar, R.; Larguinho, M.; Guedes da Silva, M.F.C.; Baptista, P.V.; Fernandes, A.R.. "Liposomes as Delivery System of a Sn(IV) Complex for Cancer Therapy". Pharmaceutical Research 33 6 (2016): 1351-1358. http://www.scopus.com/inward/record.url?eid=2-s2.0-84962193206&partnerID=MN8TOARS.
    10.1007/s11095-016-1876-6
  97. Ma, Z.; Zhang, B.; Guedes Da Silva, M.F.C.; Silva, J.; Mendo, A.S.; Baptista, P.V.; Fernandes, A.R.; Pombeiro, A.J.L.. "Synthesis, characterization, thermal properties and antiproliferative potential of copper(II) 4'-phenyl-terpyridine compounds". Dalton Transactions 45 12 (2016): 5339-5355. http://www.scopus.com/inward/record.url?eid=2-s2.0-84962516627&partnerID=MN8TOARS.
    10.1039/c5dt02744f
  98. Martins, M.; Baptista, P.V.; Mendo, A.S.; Correia, C.; Videira, P.; Rodrigues, A.S.; Muthukumaran, J.; et al. "In vitro and in vivo biological characterization of the anti-proliferative potential of a cyclic trinuclear organotin(iv) complex". Molecular BioSystems 12 3 (2016): 1015-1023. http://www.scopus.com/inward/record.url?eid=2-s2.0-84959151900&partnerID=MN8TOARS.
    10.1039/c5mb00791g
  99. Sutradhar, M.; Fernandes, A.R.; Silva, J.; Mahmudov, K.T.; Guedes Da Silva, M.F.C.; Pombeiro, A.J.L.. "Water soluble heterometallic potassium-dioxidovanadium(V) complexes as potential antiproliferative agents". Journal of Inorganic Biochemistry 155 (2016): 17-25. http://www.scopus.com/inward/record.url?eid=2-s2.0-84947721836&partnerID=MN8TOARS.
    10.1016/j.jinorgbio.2015.11.010
  100. Roma-Rodrigues, C.; Heuer-Jungemann, A.; Fernandes, A.R.; Kanaras, A.G.; Baptista, P.V.; Pedro Baptista; Antonios Kanaras; et al. "Peptide-coated gold nanoparticles for modulation of angiogenesis in vivo". International Journal of Nanomedicine 11 (2016): 2633-2639. http://www.scopus.com/inward/record.url?eid=2-s2.0-84973464753&partnerID=MN8TOARS.
    10.2147/IJN.S108661
  101. Vinhas, R.; Tolmatcheva, A.; Canto, R.; Ribeiro, P.; Lourenço, A.; Sousa, A.B.D.; Baptista, P.V.; Fernandes, A.R.. "A novel mutation in CEBPA gene in a patient with acute myeloid leukemia". Leukemia and Lymphoma 57 3 (2016): 711-713. http://www.scopus.com/inward/record.url?eid=2-s2.0-84946949603&partnerID=MN8TOARS.
    10.3109/10428194.2015.1065979
  102. Pedro Baptista; Alexandra Fernandes; Sara Figueiredo; Raquel Vinhas; Milton Cordeiro; Fabio Carlos; Soraia Mendo; Alexandra R Fernandes. "Gold nanoparticle-based theranostics: disease diagnostics and treatment using a single nanomaterial". Nanobiosensors in Disease Diagnosis (2015): 11-11. https://doi.org/10.2147%2Fndd.s60285.
    10.2147/ndd.s60285
  103. Pedrosa, P.; Vinhas, R.; Fernandes, A.; Baptista, P.V.. "Gold nanotheranostics: Proof-of-concept or clinical tool?". Nanomaterials 5 4 (2015): 1853-1879. http://www.scopus.com/inward/record.url?eid=2-s2.0-84946607128&partnerID=MN8TOARS.
    10.3390/nano5041853
  104. Restani, R.B.; Conde, J.; Pires, R.F.; Martins, P.; Fernandes, A.R.; Baptista, P.V.; Bonifácio, V.D.B.; Aguiar-Ricardo, A.. "POxylated Polyurea Dendrimers: Smart Core-Shell Vectors with IC50Lowering Capacity". Macromolecular Bioscience 15 8 (2015): 1045-1051. http://www.scopus.com/inward/record.url?eid=2-s2.0-84938964638&partnerID=MN8TOARS.
    10.1002/mabi.201500131
  105. Palma, S.I.C.J.; Carvalho, A.; Silva, J.; Martins, P.; Marciello, M.; Fernandes, A.R.; del Puerto Morales, M.; Roque, A.C.A.. "Covalent coupling of gum arabic onto superparamagnetic iron oxide nanoparticles for MRI cell labeling: Physicochemical and in vitro characterization". Contrast Media and Molecular Imaging 10 4 (2015): 320-328. http://www.scopus.com/inward/record.url?eid=2-s2.0-84938740569&partnerID=MN8TOARS.
    10.1002/cmmi.1635
  106. Palma, S.I.C.J.; Rodrigues, C.A.V.; Carvalho, A.; Morales, M.D.P.; Freitas, F.; Fernandes, A.R.; Cabral, J.M.S.; Roque, A.C.A.. "A value-added exopolysaccharide as a coating agent for MRI nanoprobes". Nanoscale 7 34 (2015): 14272-14283. http://www.scopus.com/inward/record.url?eid=2-s2.0-84939809117&partnerID=MN8TOARS.
    10.1039/c5nr01979f
  107. Mendo, A.S.; Figueiredo, S.; Roma-Rodrigues, C.; Videira, P.A.; Ma, Z.; Diniz, M.; Larguinho, M.; et al. "Characterization of antiproliferative potential and biological targets of a copper compound containing 4'-phenyl terpyridine". Journal of Biological Inorganic Chemistry 20 6 (2015): 935-948. http://www.scopus.com/inward/record.url?eid=2-s2.0-84939776841&partnerID=MN8TOARS.
    10.1007/s00775-015-1277-z
  108. Roma-Rodrigues, C.; Raposo, L.R.; Fernandes, A.R.. "MicroRNAs Based Therapy of Hypertrophic Cardiomyopathy: The Road Traveled so Far". BioMed Research International 2015 (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84945370800&partnerID=MN8TOARS.
    10.1155/2015/983290
  109. Martins, P.; Jesus, J.; Santos, S.; Raposo, L.R.; Roma-Rodrigues, C.; Baptista, P.V.; Fernandes, A.R.. "Heterocyclic anticancer compounds: Recent advances and the paradigm shift towards the use of nanomedicine's tool Box". Molecules 20 9 (2015): 16852-16891. http://www.scopus.com/inward/record.url?eid=2-s2.0-84942813231&partnerID=MN8TOARS.
    10.3390/molecules200916852
  110. Alexandra R Fernandes; Catarina Roma-Rodrigues; Roma-Rodrigues, C.; Fernandes, A.R.. "Genetics of hypertrophic cardiomyopathy: advances and pitfalls in molecular diagnosis and therapy". The Application of Clinical Genetics 7 (2014): 195-195. https://doi.org/10.2147%2Ftacg.s49126.
    10.2147/tacg.s49126
  111. Silva, Telma F. S.; Martins, Luisa; Guedes Da Silva, M. Fátima C.; Kuznetsov, Maxim L.; Fernandes, Alexandra R.; Silva, Ana; Pan, Chun-Jern; et al. "Cobalt complexes with pyrazole ligands as catalyst precursors for the peroxidative oxidation of cyclohexane: Z-ray absorption spectroscopy studies and biological applications". (2014): http://hdl.handle.net/10400.21/4927.
    10.1002/asia.201301331
  112. Luís, Daniela V.; Silva, Joana; Tomaz, Ana Isabel; Almeida, Rodrigo F. M. de; Larguinho, Miguel; Baptista, Pedro V.; Martins, Luisa; et al. "Insights into the mechanims underlyng the antiproliferative potential of a Co(II) coordination compound bearing 1,10-Phenanthroline-5,6-Dione: DNA and protein interaction studies". (2014): http://hdl.handle.net/10400.21/4945.
    10.1007/s00775-014-1110-0
  113. Silva, J.; Rodrigues, A.S.; Videira, P.A.; Lasri, J.; Charmier, A.J.; Pombeiro, A.J.L.; Fernandes, A.R.. "Characterization of the antiproliferative potential and biological targets of a trans ketoimine platinum complex". Inorganica Chimica Acta 423 PB (2014): 156-167. http://www.scopus.com/inward/record.url?eid=2-s2.0-84910138200&partnerID=MN8TOARS.
    10.1016/j.ica.2014.07.067
  114. Martins, P.; Marques, M.; Coito, L.; Pombeiro, A.J.L.; Baptista, P.V.; Fernandes, A.R.. "Organometallic compounds in cancer therapy: Past lessons and future directions". Anti-Cancer Agents in Medicinal Chemistry 14 9 (2014): 1199-1212. http://www.scopus.com/inward/record.url?eid=2-s2.0-84911497837&partnerID=MN8TOARS.
    10.2174/1871520614666140829124925
  115. Veigas, B.; Fernandes, A.R.; Baptista, P.V.. "AuNPs for identification of molecular signatures of resistance". Frontiers in Microbiology 5 AUG (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84987837082&partnerID=MN8TOARS.
    10.3389/fmicb.2014.00455
  116. Conde, J.; Larguinho, M.; Cordeiro, A.; Raposo, L.R.; Costa, P.M.; Santos, S.; Diniz, M.S.; Fernandes, A.R.; Baptista, P.V.. "Gold-nanobeacons for gene therapy: Evaluation of genotoxicity, cell toxicity and proteome profiling analysis". Nanotoxicology 8 5 (2014): 521-532. http://www.scopus.com/inward/record.url?eid=2-s2.0-84888082442&partnerID=MN8TOARS.
    10.3109/17435390.2013.802821
  117. Roma-Rodrigues, C.; Fernandes, A.R.; Baptista, P.V.. "Exosome in tumour microenvironment: Overview of the crosstalk between normal and cancer cells". BioMed Research International 2014 (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84902187969&partnerID=MN8TOARS.
    10.1155/2014/179486
  118. Mahmudov, K.T.; Guedes Da Silva, M.F.C.; Kopylovich, M.N.; Fernandes, A.R.; Silva, A.; Mizar, A.; Pombeiro, A.J.L.. "Di- and tri-organotin(IV) complexes of arylhydrazones of methylene active compounds and their antiproliferative activity". Journal of Organometallic Chemistry 760 (2014): 67-73. http://www.scopus.com/inward/record.url?eid=2-s2.0-84899461432&partnerID=MN8TOARS.
    10.1016/j.jorganchem.2013.12.019
  119. Alexandra R Fernandes; Pedro Martins; Daniela Rosa; Alexandra Fernandes; Pedro V. Baptista. "Nanoparticle Drug Delivery Systems: Recent Patents and Applications in Nanomedicine". Recent Patents on Nanomedicine 3 2 (2014): 105-118. https://doi.org/10.2174%2F1877912304666140304000133.
    DOI: 10.2174/1877912304666140304000133
  120. Silva, Telma F. S.; Smolenski, Piotr; Martins, Luisa; Guedes Da Silva, M. Fátima C.; Fernandes, Alexandra R.; Luis, Daniel; Silva, Ana; et al. "Cobalt and Zinc Compounds Bearing 1,10-Phenanthroline-5,6-dione or 1,3,5-Triaza-7-phosphaadamantane Derivatives - Synthesis, Characterization, Cytotoxicity, and Cell Selectivity Studies". (2013): http://hdl.handle.net/10400.21/2844.
    10.1002/ejic.201300197
  121. Fernandes, A.R.; Baptista, P.V.. "Nanotechnology for cancer diagnostics and therapy - an update on novel molecular players". Current Cancer Therapy Reviews 9 3 (2013): 164-172. http://www.scopus.com/inward/record.url?eid=2-s2.0-84895439537&partnerID=MN8TOARS.
    10.2174/157339470903140220144703
  122. Silva, A.; Luís, D.; Santos, S.; Silva, J.; Mendo, A.S.; Coito, L.; Silva, T.F.S.; et al. "Biological characterization of the antiproliferative potential of Co(II) and Sn(IV) coordination compounds in human cancer cell lines: A comparative proteomic approach". Drug Metabolism and Drug Interactions 28 3 (2013): 167-176. http://www.scopus.com/inward/record.url?eid=2-s2.0-84888103842&partnerID=MN8TOARS.
    10.1515/dmdi-2013-0015
  123. Gromicho, M.; Magalhães, M.; Torres, F.; Dinis, J.; Fernandes, A.R.; Rendeiro, P.; Tavares, P.; et al. "Instability of mRNA expression signatures of drug transporters in chronic myeloid leukemia patients resistant to imatinib". Oncology Reports 29 2 (2013): 741-750. http://www.scopus.com/inward/record.url?eid=2-s2.0-84872768729&partnerID=MN8TOARS.
    10.3892/or.2012.2153
  124. Santos, Susana; Marques, Vanda; Pires, Marina; Silveira, Leonor; Oliveira, Helena; Lança, Vasco; Brito, Dulce; et al. "High resolution melting : improvements in the genetic diagnosis of hypertrophic cardiomyopathy in a Portuguese cohort". (2012): http://hdl.handle.net/10451/34772.
    10.1186/1471-2350-13-17
  125. Silva, Telma F. S.; Martins, Luisa; Guedes da Silva, Maria de Fátima; Fernandes, Alexandra R.; Silva, Ana; Borralho, Pedro M.; Santos, Susana; Rodrigues, Cecília M. P.; Pombeiro, Armando. "Cobalt complexes bearing scorpionate ligands: Synthesis, characterization, cytotoxicity and DNA cleavage". (2012): http://hdl.handle.net/10400.21/5097.
    10.1039/c2dt11577h
  126. Santos, S.; Lança, V.; Oliveira, H.; Branco, P.; Silveira, L.; Marques, V.; Brito, D.; et al. "Genetic diagnosis of hypertrophic cardiomyopathy using mass spectrometry DNA arrays and high resolution melting". Revista Portuguesa de Cardiologia 30 1 (2011): 7-18. http://www.scopus.com/inward/record.url?eid=2-s2.0-79952394840&partnerID=MN8TOARS.
  127. Gromicho, M.; Dinis, J.; Magalhães, M.; Fernandes, A.R.; Tavares, P.; Laires, A.; Rueff, J.; Rodrigues, A.S.. "Development of imatinib and dasatinib resistance: Dynamics of expression of drug transporters ABCB1, ABCC1, ABCG2, MVP, and SLC22A1". Leukemia and Lymphoma 52 10 (2011): 1980-1990. http://www.scopus.com/inward/record.url?eid=2-s2.0-80053211502&partnerID=MN8TOARS.
    10.3109/10428194.2011.584005
  128. Cortez-Dias N; Varela MG; Sargento L; Brito D; Almeida A; Cerqueira R; Lança V; et al. "Left ventricular non-compaction: a new mutation predisposing to reverse remodeling?". (2009): http://europepmc.org/abstract/med/19438153.
  129. Cortez-Dias, N.; Varela, M.G.; Sargento, L.; Brito, D.; Almeida, A.; Cerqueira, R.; Lança, V.; et al. "Left ventricular non-compaction: A new mutation predisposing to reverse remodeling?,Não-compactação do ventrículo esquerdo: Uma nova mutação associada a capacidade de contra-remodelação ventricular? [16]". Revista Portuguesa de Cardiologia 28 2 (2009): 185-194. http://www.scopus.com/inward/record.url?eid=2-s2.0-65349094568&partnerID=MN8TOARS.
  130. Mira, N.P.; Lourenço, A.B.; Fernandes, A.R.; Becker, J.D.; Sá-Correia, I.. "The RIM101 pathway has a role in Saccharomyces cerevisiae adaptive response and resistance to propionic acid and other weak acids". FEMS Yeast Research 9 2 (2009): 202-216. http://www.scopus.com/inward/record.url?eid=2-s2.0-59149103060&partnerID=MN8TOARS.
    10.1111/j.1567-1364.2008.00473.x
  131. Torres, F.; Ivanova-Dragoeva, A.; Pereira, M.; Veiga, J.; Rodrigues, A.S.; Sousa, A.B.; Tavares, P.; Fernandes, A.R.. "An e6a2 BCR-ABL fusion transcript in a CML patient having an iliac chloroma at initial presentation [7]". Leukemia and Lymphoma 48 5 (2007): 1034-1037. http://www.scopus.com/inward/record.url?eid=2-s2.0-34547412407&partnerID=MN8TOARS.
    10.1080/10428190701216402
  132. Vargas, R.C.; García-Salcedo, R.; Tenreiro, S.; Teixeira, M.C.; Fernandes, A.R.; Ramos, J.; Sá-Correia, I.. "Saccharomyces cerevisiae multidrug resistance transporter Qdr2 is implicated in potassium uptake, providing a physiological advantage to quinidine-stressed cells". Eukaryotic Cell 6 2 (2007): 134-142. http://www.scopus.com/inward/record.url?eid=2-s2.0-33847188819&partnerID=MN8TOARS.
    10.1128/EC.00290-06
  133. Cerqueira, R.; Evangelista, T.; Lameiras, L.; Conceição, I.; De Carvalho, M.; Tavares, P.; Fernandes, A.R.. "Novel mutation of the myelin P0 gene (MPZ) in a Portuguese family with Charcot-Marie-Tooth type 1 disease". Sinapse 7 1 (2007): 4-9. http://www.scopus.com/inward/record.url?eid=2-s2.0-34249945579&partnerID=MN8TOARS.
  134. Teixeira MC; Monteiro P; Jain P; Tenreiro S; Fernandes AR; Mira NP; Alenquer M; et al. "The YEASTRACT database: a tool for the analysis of transcription regulatory associations in Saccharomyces cerevisiae.". Nucleic acids research 34 Database i (2006): http://europepmc.org/abstract/med/16381908.
    10.1093/nar/gkj013
  135. Teixeira, M.C.; Fernandes, A.R.; Mira, N.P.; Becker, J.D.; Sá-Correia, I.. "Early transcriptional response of Saccharomyces cerevisiae to stress imposed by the herbicide 2,4-dichlorophenoxyacetic acid". FEMS Yeast Research 6 2 (2006): 230-248. http://www.scopus.com/inward/record.url?eid=2-s2.0-33645054024&partnerID=MN8TOARS.
    10.1111/j.1567-1364.2006.00041.x
  136. Simões, T.; Mira, N.P.; Fernandes, A.R.; Sá-Correia, I.. "The SPI1 gene, encoding a glycosylphosphatidylinositol-anchored cell wall protein, plays a prominent role in the development of yeast resistance to lipophilic weak-acid food preservatives". Applied and Environmental Microbiology 72 11 (2006): 7168-7175. http://www.scopus.com/inward/record.url?eid=2-s2.0-33751006150&partnerID=MN8TOARS.
    10.1128/AEM.01476-06
  137. Coelho, T.; Santos, M.; Cerqueira, R.; Pires, M. M.; Lameiras, L.; Gabriel, H.; Fernandes, A. R.; Tavares, P.; Guimaraes, A.. "Three novel mutations of the myelin Po gene (MPZ) in Portuguese families with CMT1B". Neuromuscular Disorders 16 9-10 (2006): 665-665.
    10.1016/j.nmd.2006.05.079
  138. Fernandes, A.R.; Mira, N.P.; Vargas, R.C.; Canelhas, I.; Sá-Correia, I.. "Saccharomyces cerevisiae adaptation to weak acids involves the transcription factor Haa1p and Haa1p-regulated genes". Biochemical and Biophysical Research Communications 337 1 (2005): 95-103. http://www.scopus.com/inward/record.url?eid=2-s2.0-25844432253&partnerID=MN8TOARS.
    10.1016/j.bbrc.2005.09.010
  139. Teixeira, M.C.; Santos, P.M.; Fernandes, A.R.; Sá-Correia, I.. "A proteome analysis of the yeast response to the herbicide 2,4-dichlorophenoxyacetic acid". Proteomics 5 7 (2005): 1889-1901. http://www.scopus.com/inward/record.url?eid=2-s2.0-18844392542&partnerID=MN8TOARS.
    10.1002/pmic.200401085
  140. Vargas, R.C.; Tenreiro, S.; Teixeira, M.C.; Fernandes, A.R.; Sá-Correia, I.. "Saccharomyces cerevisiae multidrug transporter Qdr2p (Yil121wp): Localization and function as a quinidine resistance determinant". Antimicrobial Agents and Chemotherapy 48 7 (2004): 2531-2537. http://www.scopus.com/inward/record.url?eid=2-s2.0-3042619287&partnerID=MN8TOARS.
    10.1128/AAC.48.7.2531-2537.2004
  141. Fernandes, A.R.; Durão, P.J.; Santos, P.M.; Sá-Correia, I.. "Activation and significance of vacuolar H+-ATPase in Saccharomyces cerevisiae adaptation and resistance to the herbicide 2,4-dichlorophenoxyacetic acid". Biochemical and Biophysical Research Communications 312 4 (2003): 1317-1324. http://www.scopus.com/inward/record.url?eid=2-s2.0-0344495239&partnerID=MN8TOARS.
    10.1016/j.bbrc.2003.11.072
  142. Fernandes, A.R.; Sá-Correia, I.. "Transcription patterns of PMA1 and PMA2 genes and activity of plasma membrane H+-ATPase in Saccharomyces cerevisiae during diauxic growth and stationary phase". Yeast 20 3 (2003): 207-219. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037326499&partnerID=MN8TOARS.
    10.1002/yea.957
  143. Simões, T.; Teixeira, M.C.; Fernandes, A.R.; Sá-Correia, I.. "Adaptation of Saccharomyces cerevisiae to the herbicide 2,4-dichlorophenoxyacetic acid, mediated by Msn2p- and Msn4p-regulated genes: Important role of SPI1". Applied and Environmental Microbiology 69 7 (2003): 4019-4028. http://www.scopus.com/inward/record.url?eid=2-s2.0-17544401667&partnerID=MN8TOARS.
    10.1128/AEM.69.7.4019-4028.2003
  144. Fernandes, A.R.; Sá-Correia, I.. "The activity of plasma membrane H+-ATPase is strongly stimulated during Saccharomyces cerevisiae adaptation to growth under high copper stress, accompanying intracellular acidification". Yeast 18 6 (2001): 511-512. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035048535&partnerID=MN8TOARS.
    10.1002/yea.702
  145. Tenreiro, S.; Fernandes, A.R.; Sá-Correia, I.. "Transcriptional activation of FLR1 gene during Saccharomyces cerevisiae adaptation to growth with benomyl: Role of Yap1p and Pdr3p". Biochemical and Biophysical Research Communications 280 1 (2001): 216-222. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034805930&partnerID=MN8TOARS.
    10.1006/bbrc.2000.4100
  146. Fernandes, A.R.; Prieto, M.; Sá-Correia, I.. "Modification of plasma membrane lipid order and H+-ATPase activity as part of the response of Saccharomyces cerevisiae to cultivation under mild and high copper stress". Archives of Microbiology 173 4 (2000): 262-268. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034119202&partnerID=MN8TOARS.
    10.1007/s002030000138
  147. Abdallah, B.M.; Simões, T.; Fernandes, A.R.; Strauss, J.; Seiboth, B.; Sá-Correia, I.; Kubicek, C.P.. "Glucose does not activate the plasma-membrane-bound H+-ATPase but affects pmaA transcript abundance in Aspergillus nidulans". Archives of Microbiology 174 5 (2000): 340-345. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033714945&partnerID=MN8TOARS.
    10.1007/s002030000212
  148. Labbé, S.; Peña, M.M.O.; Fernandes, A.R.; Thiele, D.J.. "A copper-sensing transcription factor regulates iron uptake genes in Schizosaccharomyces pombe". Journal of Biological Chemistry 274 51 (1999): 36252-36260. http://www.scopus.com/inward/record.url?eid=2-s2.0-0040437349&partnerID=MN8TOARS.
    10.1074/jbc.274.51.36252
  149. Fernandes, A.R.; Sá-Correia, I.. "Comparative effects of Saccharomyces cerevisiae cultivation under copper stress on the activity and kinetic parameters of plasma-membrane-bound H+- ATPases PMA1 and PMA2". Archives of Microbiology 171 4 (1999): 273-278. http://www.scopus.com/inward/record.url?eid=2-s2.0-0344178092&partnerID=MN8TOARS.
    10.1007/s002030050710
  150. Fernandes, A.R.; Peixoto, F.P.; Sá-Correia, I.. "Activation of the H+-ATPase in the plasma membrane of cells of Saccharomyces cerevisiae grown under mild copper stress". Archives of Microbiology 171 1 (1998): 6-12. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032455608&partnerID=MN8TOARS.
    10.1007/s002030050671
Capítulo de livro
  1. Joana Silva; Alexandra Fernandes; P. V. Baptista. "Application of Nanotechnology in Drug Delivery". editado por Sezer, {Ali Demir. InTech, 2014.
    10.5772/58424
  2. Alexandra Fernandes. "Overview of HCM genomics and transcriptomics: molecular tools in HCM assessment for application in clinical medicine.". editado por Ltd, {IConcept Press, in press-in press. iConcept Press Ltd, 2014.
Livro
  1. Fernandes, A.R.; Baptista, P.V.. Gene silencing using multifunctionalized gold nanoparticles for cancer therapy. 2017.
    10.1007/978-1-4939-6646-2_19
  2. Machado, C.M.; Couto, F.M.; Fernandes, A.R.; Santos, S.; Freitas, A.T.. Toward a translational medicine approach for hypertrophic cardiomyopathy. 2012.
    10.1007/978-3-642-32395-9_12
Revisão de livro
  1. Roma-Rodrigues, Catarina; Mendes, Rita; Baptista, Pedro V.; Fernandes, Alexandra R.; UCIBIO - Applied Molecular Biosciences Unit; DCV - Departamento de Ciências da Vida. "Targeting Tumor Microenvironment for Cancer Therapy". http://www.scopus.com/inward/record.url?scp=85061850608&partnerID=8YFLogxK.
    https://doi.org/10.3390/ijms20040840

Outros

Outra produção
  1. Correction to: Nano-in-Micro Sildenafil Dry Powder Formulations for the Treatment of Pulmonary Arterial Hypertension Disorders: The Synergic Effect of POxylated Polyurea Dendrimers, PLGA, and Cholesterol (Part. Part. Syst. Charact, (2020), 37, (1900447), 10.1002/ppsc.19000447). 2020. Rita B. Restani; Márcia T. Tavares; Rita F. Pires; P. V. Baptista; Alexandra Fernandes; Teresa Casimiro; Vasco D. B. Bonifácio; Ana Aguiar-Ricardo. https://novaresearch.unl.pt/en/publications/8a201829-bff5-44ac-9e88-3b9745e399b3.
    10.1002/ppsc.202000251
  2. New lessons from ancient life: marine invertebrates as a source of new drugs. 2019. A. P. Rodrigo; C. Martins; L. Tanoeiro; M. Casaca; A. R. Lopes; A. Jorge Parola; A. P. Matos; et al. https://novaresearch.unl.pt/en/publications/388a1a5a-44fc-46a7-8cb5-bdb178d0d7ee.
    10.1080/07853890.2018.1561901
  3. Gold Nanoparticles in Molecular Diagnostics and Molecular Therapeutics. 2017. Ana S. Matias; Fábio F. Carlos; P. Pedrosa; Alexandra R. Fernandes; Pedro V. Baptista. https://doi.org/10.1007%2F978-3-319-63790-7_16.
    10.1007/978-3-319-63790-7_16
Atividades

Orientação

Título / Tema
Papel desempenhado
Curso (Tipo)
Instituição / Organização
2021 - Atual Nanoheaters – Localized hyperthermia for precise gene delivery
Coorientador de Daniela Ferreira
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2021 - Atual Novel ionic liquids as targeted therapy drugs for lung cancer
Coorientador de Dário Valezim Silva
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2021 - Atual From proteins to Bacteria: a multidisciplinar approach for the rational development of new anti-biofilm and antibacterial agents
Coorientador de João Paquete Ferreira
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2019 - Atual Towards the molecular mechanism underlying the association between preterm birth and periodontal disease
Coorientador de Joana Couceiro
Biologia (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2019 - Atual Towards the molecular mechanism underlying resistance in Chronic Myeloid leukemia: new therapies
Orientador de Bilal Rabah Qasim Abdulmawjood
Centro Interuniversitário de História das Ciências e da Tecnologia, Portugal
2018 - Atual Transdermal delivery systems based on natural polymeric biomaterials
Coorientador de Diana Filipa Vieira Araújo
Engenharia Química (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2018 - Atual Targeting liver ischemia reperfusion injury: nanoformulations for gene silencing
Coorientador de Ana Margarida Ferreira da Silva
i3Du (Doutoramento)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2014 - Atual Unraveling the host specificity within pyogenic streptococci".
Orientador de Cinthia Barroco
Biologia (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2022/03/01 - 2026/02/27 (Gold4TME): Modulation of tumor microenvironment via combinatorial gold nanomedicines
Orientador
Biologia (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2016 - 2021/02/26 De pigmentos e toxinas: uma abordagem integradora ao potencial biotecnológico de um poliqueta marinho
Coorientador de Ana Rodrigo
Ambiente (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2010 - 2020 >35 Master Thesis in cancer therapy
Orientador
2016 - 2019 Gold Nanoparticles to Tackle Drug Resistance in Cancer
Orientador de Pedro Miguel Pinto Gonçalves Gouveia Pedrosa
Biociências Moleculares (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2018 - 2018 Uncovering the role of blood vessels during spinal cord regeneration in zebrafish
Coorientador
Genética Molecular e Biomedicina (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2014 - 2018 Gold Nanoparticles for nanotherasnostic in Leukaemia addressing CML
Coorientador de Raquel Patricia Gomes Silvestre Vinhas.
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2017 - 2017 Gene Espression Analysis in Cardiac and Adipose Derived Fibroblasts: potential influence of origin and in vitro culture
Coorientador
Engenharia Biomédica (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2011 - 2016 Transcriptome and proteome profiling of canine mammary tumors: dog as a genetic model for unrevealing mammary cancer molecular signatures
Orientador de Luís Manuel Redondo Raposo
Biologia (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2014/09/01 - 2015/10/05 Novos genes no diagnóstico genético de miocardiopatia hipertrófica
Orientador
Engenharia Biotecnológica (Mestrado)
Universidade de Aveiro Instituto Superior de Contabilidade e Administração, Portugal

Júri de grau académico

Tema
Tipo de participação
Nome do candidato (Tipo de grau)
Instituição / Organização
2018 Diseño y propiedades de compuestos heterolépticos derivados de Ru (?6-pcimeno)
Arguente
Jorge Lado Sanjurjo (Doutoramento)
2017 miRNA-143 and miRNA-145 Modulation in colorectal cancer: from anticancer activity to drug sensitization
Vogal
Sofia Estevão Gomes (Doutoramento)
2017 Diseño e estudio de compuestos de rutenio con actividad biológica
Arguente principal
Oscar Armando Lenis-Rojas (Doutoramento)
2017 Identifying novel chemotypes against breast cancer: Design, synthesis and biological evaluation
Arguente
Chandramohan Bathula (Doutoramento)
2016 Biophysical and biological studies of ternary copper(ii) complexes anchored polyethyleneimine – in vitro approach for the search of polymeric anticancer drugs
Arguente
Kumar Sugumar (Doutoramento)
2016 The role of alpha2,3 and alpha2,6 sialylation in functional aspects of dendritic cells
Vogal
Hélio Santos Crespo (Doutoramento)
2016 Development of Field Effect sensors for gene expression analysis: Application to cancer diagnosis
Vogal
Bruno Miguel Ribeiro Veigas (Doutoramento)
2015 Design and Synthesis of small molecule modulators of p53
Arguente
Carlos Jorge Azevedo Costa Pinheiro. (Doutoramento)
2015 Engineered MRI nanoprobes based on superparamagnetic iron oxide nanoparticles
Vogal
Susana Palma (Doutoramento)
2014 Base Genética da Hipercolesterolemia Familiar em Portugal
Arguente
Ana Catarina dos Santos Alves. (Doutoramento)
2014 Gold Nanoparticles for the detection of DNA adducts as biomarkers od exposure to acrylamide
Vogal
Miguel Ângelo Rodrigues Larguinho (Doutoramento)

Arbitragem científica em conferência

Nome da conferência Local da conferência
1997 - 2021 > 100 poster in international meeting -

Comissão de avaliação

Descrição da atividade
Tipo de assessoria
Instituição / Organização Entidade financiadora
2018 - 2020 The Royal Society, UK
Avaliador
2017 - 2020 UK Welcome Trust
Avaliador
2017 - 2020 Czech Science Foundation, National Science Center Poland
Avaliador
2015 - 2020 ANR - Agence Nationale de la Researche
Avaliador
2019 - 2019 Bolsas Doutoramento FCT/MCTES
2019 - 2019 Georg Forster Research Fellowships for Experienced Researchers, Alexander von Humboldt-Stiftung Foundation
Avaliador
2015 - 2016 Austrian Science Fund I projects
Avaliador

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2019/07 - 2019/09 Animal experimentation Course - FELASA Type B Curso de Experimentação animal (Curso de Especialização Tecnológica) Universidade de Lisboa Faculdade de Farmácia, Portugal
Distinções

Outra distinção

2013 Prémio Fundação Everis - Heargenetics SA
2002 Award of best poster presentation