ANDREIA FILIPA FERREIRA PEIXOTO (361D-5B5E-A5C1)

Curriculum Vitae

ANDREIA FILIPA FERREIRA PEIXOTO

Andreia Peixoto graduated in Biochemistry by the Faculty of Sciences UPorto in 2012 and completed her MSc degree in Biochemistry at the same institution in 2014, where she received a merit scholarship for exceptional academic performance. During her Master and PhD, Andreia Peixoto initiated her studies on cell-surface protein glycosylation associated with malignant transformations of the urinary bladder, envisaging biomarkers discovery for theragnostic applications. During her Master and PhD, as a member of Experimental Pathology and Therapeutics Group (IPO-Porto) and Tumour and Microenvironments Interactions group (INEB), she got familiarized with state-of-the-art in vitro techniques, trough the collaboration with IPATIMUP (Institute of Molecular Pathology and Immunology of the University of Porto). Currently, she is a Junior Researcher at IPO-Porto (CI-IPOP) and i3S, being focused on glycan-mediated immunosupressive mechanisms envisaging novel cancer immunotherapies. In this context, she has proficiency in glycomics and glycoproteomics workflows as well as in novel gene editing technologies and immuno-oncology. She is currently the principal investigator of an FCT funded project for cancer glycovaccines development (https://doi.org/10.54499/2022.03621.PTDC). She often lectures to BSc and MSc courses and actively participates in glycobiology meetings and workshops. She holds 2 book chapters, 1 international patent, and 29 publications (36% as first author; 1420 citations; H-index: 20) in relevant peer-reviewed journals in glycobiology/proteomics, oncoglycobiology, cancer biomarkers and therapeutics. As part of an Oncology Center of Excellence, her research presents a strong translational and market-oriented character, which is expected to translate into novel glycan-based cancer tools.

Ler resumo completo ↓

Identificação

Identificação pessoal

Nome completo: ANDREIA FILIPA FERREIRA PEIXOTO

Nomes de citação

Peixoto, Andreia

Identificadores de autor

Ciência ID: 361D-5B5E-A5C1
ORCID iD: 0000-0001-9514-0775

Endereços de correio eletrónico

andreia.peixoto@ipoporto.min-saude.pt (Profissional)

Telefones

Telefone

(+351) 225084000 Ext.: 5110 (Profissional)

Moradas

Instituto Português de Oncologia do Porto (IPO-Porto). Rua Dr. António Bernardino de Almeida, 4200-072, Porto, Porto, Portugal (Profissional)

Domínios de atuação

Ciências Naturais - Ciências Biológicas
Ciências Médicas e da Saúde - Biotecnologia Médica - Biotecnologia Aplicada à Saúde

Idiomas

Idioma	Conversação	Leitura	Escrita	Compreensão	Peer-review
Inglês	Utilizador independente (B2)	Utilizador proficiente (C1)	Utilizador independente (B2)	Utilizador proficiente (C1)	Utilizador proficiente (C1)
Português (Idioma materno)

Formação

	Grau	Classificação
2025/03/10 - 2025/03/12 Frequentou	International Course of Immunotherapy (Curso de Especialização Tecnológica) Precision Immunology Institute at the Icahn School of Medicine, Estados Unidos
2023/10/12 - 2023/10/12 Concluído	Life Science Intellectual Property Management and Exploitation (Outros) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
2023/06/13 - 2023/06/29 Concluído	Research Project Management course (Outros) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2021 - 2021 Concluído	Good Practices in In Vitro Research Course (Curso de Especialização Tecnológica) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2016/01/01 - 2020/10/15 Concluído	Doctoral Degree in Biomedical Sciences (Doutoramento) Especialização em Doctoral Degree Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal "Exploring glycobiomarkers for advanced stage bladder cancer: adding the influence of hypoxia to the equation" (TESE/DISSERTAÇÃO)	Summa Cum Laude
2018/03/19 - 2018/03/22 Concluído	Descriptive statistics and SPSS course (Curso Técnico Superior Profissional) Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
2015/09/07 - 2015/09/18 Concluído	Course in laboratory animal science (Curso de Especialização Tecnológica) Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal	Category C
2013/10/24 - 2014/01/09 Concluído	English B2.2 course (Curso médio) Especialização em B2.2 (vantage) Universidade do Porto Faculdade de Letras, Portugal	B2.2 (vantage)
2014 Concluído	Master's degree in Biochemistry (Mestrado) Especialização em Master Universidade do Porto Faculdade de Ciências, Portugal "Hypoxic regulation of glycosylation in bladder cancer" (TESE/DISSERTAÇÃO)	18 valores
2012 Concluído	First Degree in Biochemistry (Licenciatura) Especialização em Bachelor Universidade do Porto Faculdade de Ciências, Portugal "Surfactant self-aggregation studies in aqueous solution and interaction with DNA" (TESE/DISSERTAÇÃO)	15 valores

Percurso profissional

Ciência

	Categoria Profissional Instituição de acolhimento	Empregador
2020/10/15 - Atual	Investigador visitante (Investigação)	Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
	Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2021/01/04 - 2030/01/01	Investigador Contratado (Investigação)	Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
	Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
2014/09/15 - 2015/09/15	Estagiário de Investigação (Investigação)	TREAT U – Biotechnology, Portugal

Docência no Ensino Superior

	Categoria Profissional Instituição de acolhimento	Empregador
2022 - Atual	Monitor (Docente Universitário)	Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
	Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2020/03/01 - 2020/09/15	Professor Adjunto Convidado (Docente Ensino Superior Politécnico)	Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
	Instituto Politécnico do Porto Escola Superior de Saúde, Portugal

Outros

	Categoria Profissional Instituição de acolhimento	Empregador
2016/01/01 - 2020/10/15	PhD Student researching on the topic "Exploring glycobiomarkers for advanced stage bladder cancer: adding the influence of hypoxia to the equation"	Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
	Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal (...)
2013/09/09 - 2014/12/22	MSc student researching for the MSc Thesis on the topic "Hypoxic regulation of Glycosylation in Bladder Cancer" in the Experimental Pathology and Therapeutics Group at IPO-Porto research center	Universidade do Porto Faculdade de Ciências, Portugal

2011/09/01 - 2012/09/15	Bsc student researching for the BSc thesis in the Molecular Energetics, Colloids and Bio-interfaces group of the Centro de Investigação em Química da Universidade do Porto, CIQ(U.P.)	Universidade do Porto Faculdade de Ciências, Portugal

Projetos

Bolsa

	Designação	Financiadores
2021/10/01 - Atual	Phosphoproteomics of hypoxic and glucose deprived bladder cancer cells: the missing link towards systems oncology. #EPIC-XS-0000341 Investigador Universiteit Utrecht, Países Baixos	European Proteomics Infrastructure Consortium Providing Access Em curso
2016/01/01 - 2030/12/31	Institute for Research and Innovation in Health Sciences UID/BIM/04293/2019 LA/P/0070/2020 10.54499/LA/P/0070/2020 2023.06366.CEECIND/CP2864/CT0001 Bolseiro de Cientista Convidado Instituto Nacional de Engenharia Biomédica, Portugal Universidade do Porto, Portugal Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal	Fundação para a Ciência e a Tecnologia Em curso
2025/02/01 - 2028/01/31	CAR T-Matters - Transforming the CAR T-cell therapy landscape in Portugal 18427 Investigador Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal	Fundo Europeu de Desenvolvimento Regional (FEDER) Em curso
2024/02/04 - 2025/02/04	GlycoGuard: Glycophenotyping Early Signs of Gastric Cancer Towards Life Saving Interventions LPCC-NRN 2024 Orientador Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal	Liga Portuguesa Contra o Cancro Em curso
2022/01/01 - 2024/12/31	RESOLVE: Rational Design of Multivalent Glycocode-Inspired Nanovaccines for Gastric Cancer Immunotherapy PTDC/MED-OUT/2512/2021 10.54499/PTDC/MED-OUT/2512/2021 Investigador Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal Universidade de Aveiro, Portugal Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal	Fundação para a Ciência e a Tecnologia Em curso
2023/03/01 - 2024/08/31	REVERENT: PRE-CLINICAL VALIDATION OF A GLYCOCODE-INSPIRED VACCINE FOR BLADDER CANCER IMMUNOTHERAPY 2022.03621.PTDC 10.54499/2022.03621.PTDC Investigador responsável Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal Instituto de Astrofísica e Ciências do Espaço, Portugal	Fundação para a Ciência e a Tecnologia Em curso
2022/01/01 - 2024/01/01	GlycoSensor: Pre-Clinical Validation of a Point-of-Care Biosensor for Cancer Detection in Whole Blood Based on Abnormal Glycosylation 0 Investigador Universal Biosensors Pty Ltd, Austrália	Concluído
2022/01/01 - 2023/01/01	glycoINSPIRER: PRE-CLINICAL VALIDATION OF A GLYCOCODE-INSPIRED VACCINE FOR BLADDER CANCER IMMUNOTHERAPY LPCC-NRN 2022 Orientador Liga Portuguesa Contra o Cancro Núcleo Regional do Norte, Portugal	Concluído
2020/05 - 2020/08	GLYCOVID-19 Testing existing glycan-based drugs to neutralize SARS-CoV- 2 140_596817822 Outra	Fundação para a Ciência e a Tecnologia Em curso
2016/01 - 2020/01	Exploring glycobiomarkers for advanced stage bladder cancer: adding the influence of hypoxia to the equation SFRH/BD/111242/2015 Bolseiro de Doutoramento	Fundação para a Ciência e a Tecnologia Concluído

Projeto

	Designação	Financiadores
2024/10/01 - 2030/09/30	NextGenGlycoVacs: Next generation glycovaccines for immunologically cold tumours 2023.06366.CEECIND/CP2864/CT0001 10.54499/2023.06366.CEECIND/CP2864/CT0001 Investigador responsável Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal	Fundação para a Ciência e a Tecnologia Em curso

Outro

	Designação	Financiadores
2021 - 2025/12/31	RISE: Health Research Network: From Lab to Community Health LA/P/0053/2020 Investigador	Em curso
2024/09/01 - 2025/09/01	Deciphering the Influence of CD276 glycocode in Gastric Cancer Immunoregulation ESS-IPP MSc Orientador Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal	Em curso

Produções

Publicações

Artigo em conferência	Peixoto, Andreia. "Definindo o papel da glicosilação na agressividade do cancro de bexiga: Impacto do microambiente tumoral". Trabalho apresentado em 5º Encontro Nacional de Jovens Investigadores em Oncologia – ENJIO, 2023. Publicado
Artigo em revista	Peixoto, Andreia; Ferreira, Dylan; Miranda, Andreia; Relvas-Santos, Marta; Freitas, Rui; Veth, Tim S.; Brandão, Andreia; et al. "Multilevel Plasticity and Altered Glycosylation Drive Aggressiveness in Hypoxic and Glucose-Deprived Bladder Cancer Cells". iScience (2025): 111758. https://doi.org/10.1016/j.isci.2025.111758. Acesso aberto • Publicado • 10.1016/j.isci.2025.111758 Freitas, Rui; Ferreira, Eduardo; Miranda, Andreia; Ferreira, Dylan; Relvas-Santos, Marta; Castro, Flávia; Santos, Beatriz; et al. "Targeted and Self-Adjuvated Nanoglycovaccine Candidate for Cancer Immunotherapy". ACS Nano (2024): http://dx.doi.org/10.1021/acsnano.3c12487. Acesso aberto • Publicado • 10.1021/acsnano.3c12487 Ferreira, Eduardo; Ferreira, Dylan; Relvas-Santos, Marta; Freitas, Rui; Soares, Janine; Azevedo, Rita; Afonso, Luís Pedro; et al. "Aberrantly Glycosylated GLUT1 as a Poor Prognosis Marker in Aggressive Bladder Cancer". International Journal of Molecular Sciences 25 6 (2024): 3462. http://dx.doi.org/10.3390/ijms25063462. Aceite para publicação • 10.3390/ijms25063462 Freitas, Rui; Miranda, Andreia; Ferreira, Dylan; Relvas-Santos, Marta; Castro, Flávia; Ferreira, Eduardo; Gaiteiro, Cristiana; et al. "A multivalent CD44 glycoconjugate vaccine candidate for cancer immunotherapy". Journal of Controlled Release 367 (2024): 540-556. http://dx.doi.org/10.1016/j.jconrel.2024.01.065. Publicado • 10.1016/j.jconrel.2024.01.065 Freitas, Rui; Peixoto, Andreia; Ferreira, Eduardo; Miranda, Andreia; Santos, Lúcio Lara; Ferreira, José Alexandre. "Immunomodulatory glycomedicine: Introducing next generation cancer glycovaccines". Biotechnology Advances 65 (2023): 108144. http://dx.doi.org/10.1016/j.biotechadv.2023.108144. Aceite para publicação • 10.1016/j.biotechadv.2023.108144 Peixoto, Andreia; Miranda, Andreia; Santos, Lúcio Lara; Ferreira, José Alexandre. "A Roadmap for Translational Cancer Glycoimmunology at Single Cell Resolution". Journal of Experimental & Clinical Cancer Research (2022): 10.1186/s13046-022-02335-z Cristiana Gaiteiro; Janine Soares; Marta Relvas-Santos; Andreia Peixoto; Dylan Ferreira; Andreia Brandão; Elisabete Fernandes; et al. "Glycoproteogenomics characterizes the CD44 splicing code driving bladder cancer invasion". Theranostics 12 7 (2022): 3150-3177. https://www.thno.org/v12p3150.htm. Publicado • 10.1101/2021.09.04.458979 Peixoto, Andreia; Ferreira, Dylan; Azevedo, Rita; Freitas, Rui; Fernandes, Elisabete; Relvas-Santos, Marta; Gaiteiro, Cristiana; et al. "Glycoproteomics identifies HOMER3 as a potentially targetable biomarker triggered by hypoxia and glucose deprivation in bladder cancer". Journal of Experimental & Clinical Cancer Research 40 1 (2021): http://dx.doi.org/10.1186/s13046-021-01988-6. Acesso aberto • Publicado • 10.1186/s13046-021-01988-6 Ferreira, José Alexandre; Relvas-Santos, Marta; Peixoto, Andreia; Silva, André M.N.; Santos, Lúcio Lara. "Glycoproteogenomics: Setting the Course for Next Generation Cancer Neoantigens Discovery for Cancer Vaccines". Genomics, Proteomics & Bioinformatics (2021): http://dx.doi.org/10.1016/j.gpb.2021.03.005. Acesso aberto • Publicado • 10.1016/j.gpb.2021.03.005 Andreia Peixoto; Rui A Freitas; Dylan A Ferreira; Marta Relvas-Santos; Paula Paulo; Marta Cardoso; Janine Soares; et al. "Metabolomics, Transcriptomics and Functional Glycomics Reveals Bladder Cancer Cells Plasticity and Enhanced Aggressiveness Facing Hypoxia and Glucose Deprivation". (2021): https://doi.org/10.1101/2021.02.14.431133. 10.1101/2021.02.14.431133 Sofia Cotton; Dylan Ferreira; Janine Soares; Andreia Peixoto; Marta Relvas-Santos; Rita Azevedo; Paulina Piairo; et al. "Target Score: A Proteomics Data Selection Tool Applied to Esophageal Cancer Identifies GLUT1-Sialyl Tn Glycoforms as Biomarkers of Cancer Aggressiveness". International Journal of Molecular Sciences (2021): https://doi.org/10.3390/ijms22041664. Publicado • 10.3390/ijms22041664 Fernandes, Elisabete; Freitas, Rui; Ferreira, Dylan; Soares, Janine; Azevedo, Rita; Gaiteiro, Cristiana; Peixoto, Andreia; et al. "Nucleolin-Sle A Glycoforms as E-Selectin Ligands and Potentially Targetable Biomarkers at the Cell Surface of Gastric Cancer Cells". Cancers 12 4 (2020): 861. http://dx.doi.org/10.3390/cancers12040861. Publicado • 10.3390/cancers12040861 Fernandes, Elisabete; Sores, Janine; Cotton, Sofia; Peixoto, Andreia; Ferreira, Dylan; Freitas, Rui; Reis, Celso A.; Santos, Lúcio Lara; Ferreira, José Alexandre. "Esophageal, gastric and colorectal cancers: Looking beyond classical serological biomarkers towards glycoproteomics-assisted precision oncology". Theranostics 10 11 (2020): 4903-4928. http://dx.doi.org/10.7150/thno.42480. Publicado • 10.7150/thno.42480 Fernandes, Elisabete; Ferreira, Dylan; Peixoto, Andreia; Freitas, Rui; Relvas-Santos, Marta; Palmeira, Carlos; Martins, Gabriela; et al. "Glycoengineered nanoparticles enhance the delivery of 5-fluoroucil and paclitaxel to gastric cancer cells of high metastatic potential". International Journal of Pharmaceutics 570 (2019): 118646. http://dx.doi.org/10.1016/j.ijpharm.2019.118646. Acesso aberto • Publicado • 10.1016/j.ijpharm.2019.118646 Peixoto, Andreia; Relvas-Santos, Marta; Azevedo, Rita; Santos, Lúcio Lara; Ferreira, José Alexandre. "Protein Glycosylation and Tumor Microenvironment Alterations Driving Cancer Hallmarks". Frontiers in Oncology 9 (2019): http://dx.doi.org/10.3389/fonc.2019.00380. Acesso aberto • Publicado • 10.3389/fonc.2019.00380 Neves, Manuel; Azevedo, Rita; Lima, Luís; Oliveira, Marta I.; Peixoto, Andreia; Ferreira, Dylan; Soares, Janine; et al. "Exploring sialyl-Tn expression in microfluidic-isolated circulating tumour cells: A novel biomarker and an analytical tool for precision oncology applications". New Biotechnology 49 (2019): 77-87. http://dx.doi.org/10.1016/j.nbt.2018.09.004. Publicado • 10.1016/j.nbt.2018.09.004 Azevedo, Rita; Soares, Janine; Gaiteiro, Cristiana; Peixoto, Andreia; Lima, Luís; Ferreira, Dylan; Relvas-Santos, Marta; et al. "Glycan affinity magnetic nanoplatforms for urinary glycobiomarkers discovery in bladder cancer". Talanta 184 (2018): 347-355. http://dx.doi.org/10.1016/j.talanta.2018.03.028. Publicado • 10.1016/j.talanta.2018.03.028 Azevedo, Rita; Gaiteiro, Cristiana; Peixoto, Andreia; Relvas-Santos, Marta; Lima, Luís; Santos, Lúcio Lara; Ferreira, José Alexandre. "CD44 glycoprotein in cancer: a molecular conundrum hampering clinical applications". Clinical Proteomics 15 1 (2018): http://dx.doi.org/10.1186/s12014-018-9198-9. Publicado • 10.1186/s12014-018-9198-9 Azevedo R; Soares J; Peixoto A; Cotton S; Lima L; Santos LL; Ferreira JA. "Circulating tumor cells in bladder cancer: Emerging technologies and clinical implications foreseeing precision oncology.". Urologic oncology (2018): http://europepmc.org/abstract/med/29530466. 10.1016/j.urolonc.2018.02.004 Peixoto, Andreia. "Sialyl-Tn identifies muscle-invasive bladder cancer basal and luminal subtypes facing decreased survival, being expressed by circulating tumor cells and metastases.". Urologic oncology (2017): http://europepmc.org/abstract/med/28911924. 10.1016/j.urolonc.2017.08.012 Peixoto, Andreia. "Over forty years of bladder cancer glycobiology: Where do glycans stand facing precision oncology?". Oncotarget (2017): http://europepmc.org/abstract/med/28767404. 10.18632/oncotarget.19433 Cotton, Sofia; Azevedo, Rita; Gaiteiro, Cristiana; Ferreira, Dylan; Lima, Luís; Peixoto, Andreia; Fernandes, Elisabete; et al. "Targeted O-glycoproteomics explored increased sialylation and identified MUC16 as a poor prognosis biomarker in advanced-stage bladder tumours". Molecular Oncology 11 8 (2017): 895-912. http://dx.doi.org/10.1002/1878-0261.12035. Publicado • 10.1002/1878-0261.12035 Ferreira, José Alexandre; Magalhães, Ana; Gomes, Joana; Peixoto, Andreia; Gaiteiro, Cristiana; Fernandes, Elisabete; Santos, Lúcio Lara; Reis, Celso A.. "Protein glycosylation in gastric and colorectal cancers: Toward cancer detection and targeted therapeutics". Cancer Letters 387 (2017): 32-45. http://dx.doi.org/10.1016/j.canlet.2016.01.044. Publicado • 10.1016/j.canlet.2016.01.044 Peixoto, Andreia; Fernandes, Elisabete; Gaiteiro, Cristiana; Lima, Luís; Azevedo, Rita; Soares, Janine; Cotton, Sofia; et al. "Hypoxia enhances the malignant nature of bladder cancer cells and concomitantly antagonizes protein O-glycosylation extension". Oncotarget 7 39 (2016): 63138-63157. https://doi.org/10.18632/oncotarget.11257. Publicado • 10.18632/oncotarget.11257 Peixoto, Andreia. "Abnormal glycosylation in Borrmann type IV gastric cancer: insight for guided therapeutics". Revista Portuguesa de Cirurgia 37 (2016): http://www.scielo.mec.pt/scielo.php?pid=S1646-69182016000400003&script=sci_arttext&tlng=es. Publicado Ferreira, José Alexandre; Peixoto, Andreia; Neves, Manuel; Gaiteiro, Cristiana; Reis, Celso A.; Assaraf, Yehuda G.; Santos, Lúcio Lara. "Mechanisms of cisplatin resistance and targeting of cancer stem cells: Adding glycosylation to the equation". Drug Resistance Updates 24 (2016): 34-54. http://dx.doi.org/10.1016/j.drup.2015.11.003. Publicado • 10.1016/j.drup.2015.11.003 Lima L; Gaiteiro C; Peixoto A; Soares J; Neves M; Santos LL; Ferreira JA. "Reference Genes for Addressing Gene Expression of Bladder Cancer Cell Models under Hypoxia: A Step Towards Transcriptomic Studies.". (2016): http://europepmc.org/abstract/med/27835695. Fernandes, Elisabete; Peixoto, Andreia; Neves, Manuel; Afonso, Luís Pedro; Santos, Lúcio Lara; Ferreira, José Alexandre. "Humoral response against sialyl-LeA glycosylated protein species in esophageal cancer: Insights for immunoproteomic studies". ELECTROPHORESIS 36 23 (2015): 2902-2907. http://dx.doi.org/10.1002/elps.201500270. Publicado • 10.1002/elps.201500270 Azevedo R; Ferreira JA; Peixoto A; Neves M; Sousa N; Lima A; Santos LL. "Emerging antibody-based therapeutic strategies for bladder cancer: A systematic review.". (2015): http://europepmc.org/abstract/med/26196222. 10.1016/j.jconrel.2015.07.002 Peixoto, Andreia. "New trends in guided nanotherapies for digestive cancers: A systematic review.". Journal of controlled release : official journal of the Controlled Release Society (2015): http://europepmc.org/abstract/med/25957905. 10.1016/j.jconrel.2015.05.003 Costa C; Pereira S; Lima L; Peixoto A; Fernandes E; Neves D; Neves M; et al. "Abnormal Protein Glycosylation and Activated PI3K/Akt/mTOR Pathway: Role in Bladder Cancer Prognosis and Targeted Therapeutics.". (2015): http://europepmc.org/abstract/med/26569621. Santos, Júlio; Fernandes, Elisabete; Ferreira, José Alexandre; Lima, Luís; Tavares, Ana; Peixoto, Andreia; Parreira, Beatriz; et al. "P53 and Cancer-Associated Sialylated Glycans Are Surrogate Markers of Cancerization of the Bladder Associated with Schistosoma haematobium Infection". PLoS Neglected Tropical Diseases 8 12 (2014): e3329. http://dx.doi.org/10.1371/journal.pntd.0003329. Acesso aberto • Publicado • 10.1371/journal.pntd.0003329
Capítulo de livro	Peixoto, Andreia; Cotton, Sofia; Santos, Lúcio Lara; Ferreira, José Alexandre. "The Tumour Microenvironment and Circulating Tumour Cells: A Partnership Driving Metastasis and Glycan-Based Opportunities for Cancer Control". In Advances in Experimental Medicine and Biology, 1-33. Springer International Publishing, 2021. Publicado • 10.1007/978-3-030-73119-9_1 Peixoto, Andreia. "Alterações Moleculares no Cancro da Bexiga: Biomarcadores para Terapêutica Guiada". In Tumores Malignos- tracto genito-urinário, 217-226. Portugal: Grupo Português Génito-Urinário, 2016. Publicado
Poster em conferência	Lourenço, Camila; Miranda, Andreia; Ferreira, Dylan; Relvas-Santos, Marta; Freitas, Rui; Peixoto, Andreia; Santos, Lúcio; Maria José Oliveira; Ferreira, José Alexandre. "GlycoMAPP - Exploring the Impact of Glycosylation on Macrophage Polarization in the Context of Tumour Progression". Trabalho apresentado em 2nd Young Researchers Day, 2024. Peixoto, Andreia; Miranda, Andreia; Ferreira, Dylan; Freitas, Rui; Relvas-Santos, Marta; Ferreira, Eduardo; Cotton, Sofia; et al. "Definindo o papel da glicosilação na agressividade do cancro de bexiga: Impacto do microambiente tumoral". Trabalho apresentado em IPO-Porto Summit, 2024. Freitas, Rui; Miranda, Andreia; Ferreira, Dylan; Relvas-Santos, Marta; Castro, Flávia; Ferreira, Eduardo; Gaiteiro, Cristiana; et al. "Pre-clinical Validation of a Multivalent CD44 Glycoconjugate Vaccine for Cancer Immunotherapy". Trabalho apresentado em 1st Young Researcher's Day, 2023. Ferreira, Eduardo; Freitas, Rui; Miranda, Andreia; Ferreira, Dylan; Relvas-Santos, Marta; Castro, Flávia; Palmeira, Carlos; et al. "A Targeted and Self-Adjuvated PLGA MUC16-Tn Nanoglycovaccine Candidate for Cancer Immunotherapy". Trabalho apresentado em 1st Young Researcher's Day, 2023. Santos, Beatriz; Ferreira, Dylan; Relvas-Santos, Marta; Peixoto, Andreia; Santos, Lúcio; Ferreira, José. "Unravelling the glycomics signature of formalin-fixed paraffin-embedded gastric cancer tissues". Trabalho apresentado em 1st Young Researcher's Day, 2023. Soares, Janine; Ferreira, Dylan; Miranda, Andreia; Relvas-Santos, Marta; Brandão, Andreia; Freitas, Rui; Ferreira, Eduardo; et al. "Glycosylation as a driver of Colorectal cancer aggressiveness". Trabalho apresentado em 1st Young Researchers¿s Day, 2023. Dourado-Gonçalves, Martina; Freitas, Rui; Ferreira, Dylan; Relvas-Santos, Marta; Paulo, Paula; Lara Santos, Lúcio; Ferreira, José Alexandre; Peixoto, Andreia. "Functional Glycoproteomics Characterization of Gastric Cancer Cells Expressing Immature O-Glycans". Trabalho apresentado em 1st Young Researcher's Day, 2023. Relvas-Santos, Marta; Peixoto, Andreia; Ferreira, Dylan; Lara Santos, Lúcio; Silva, André M. N.; Ferreira, José Alexandre. "Exploiting Glycoengineered Simple Cells and Targeted O-glycoproteomics Towards Bladder Cancer Neoantigens". Trabalho apresentado em 1st Young Researchers' Day, 2023. Freitas, Rui; Miranda, Andreia; Ferreira, Dylan; Gaiteiro, Cristiana; Ferreira, Eduardo; Relvas-Santos, Marta; Soares, Janine; et al. "Production and pre-clinical evaluation of immunogenic CD44 glycoconjugates: setting the molecular bases for novel multivalent anti-cancer glycovaccines". Trabalho apresentado em Trabalho apresentado no XLVIII Annual Meeting of the Portuguese Society for Immunology, 2023. Miranda, Andreia; Ferreira, Dylan; Freitas, Rui; Relvas-Santos, Marta; Palmeira, Carlos; Paulo, Paula; Castro, Flávia; et al. "Cancer-associated short-chain O-GalNAc glycans induce an immunosupressive bladder cancer phenotype by impairing dendritic cells function. Trabalho apresentado no XLVII Annual Meeting of the Portuguese Society for Immunology.". Trabalho apresentado em XLVII Annual Meeting of the Portuguese Society for Immunology, 2022. Peixoto, Andreia. "Metabolomics, Transcriptomics and Functional Glycomics Reveals Bladder Cancer Cells Plasticity and Enhanced Aggressiveness Facing Hypoxia and Glucose Deprivation". Trabalho apresentado em 27th PORTO CANCER MEETING, 2021. Ferreira, Dylan; Freitas, Rui; Fernandes, Elisabete; Gaiteiro, Cristiana; Peixoto, Andreia; Cotton, Sofia; Palmeira, Carlos; et al. "Nucleolin-SLeA as E-Selectin Ligands and Potentially Targetable Biomarkers at the Cell Surface of Gastric Cancer Cells: a flow cytometry-assisted approach". Trabalho apresentado em XVII Congress of the Iberian Society of Cytometry, 2021. Peixoto, Andreia. "Exploring the CA19-9 glycoproteome of Borrmann type IV advanced gastric cancer for guided therapeutics". Trabalho apresentado em 29th International Carbohydrate Symposium, 2018. Peixoto, Andreia. "Hypoxia enhances the malignant nature of bladder cancer cells and concomitantly antagonizes protein O-glycosylation extension". Trabalho apresentado em 29th International Carbohydrate Symposium, 2018. Peixoto, Andreia; Fernandes, Elisabete; Gaiteiro, Cristiana; Lima, Luís; Azevedo, Rita; Soares, Janine; Cotton, Sofia; et al. "Hypoxia enhances the malignant nature of bladder cancer cells and concomitantly antagonizes protein O-glycosylation". Trabalho apresentado em 29th International Carbohydrate Symposium (ICS 2018) by Peixoto A, 2018. Peixoto, Andreia. "Humoral response against sialyl-Lea expressing glycoproteins in esophageal cancer: insights for immunoproteomic studies". Trabalho apresentado em Esophageal and Gastric Cancer Initiative, 2016. Peixoto, Andreia. "Abnormal Glycosylation in Borrmann Type IV gastric cancer: insight for guided therapeutics". Trabalho apresentado em Esophageal and Gastric Cancer Initiative, 2016. Peixoto, Andreia. "Emerging Antibody-Based Therapeutic Strategies For Bladder Cancer: A Systematic Review". Trabalho apresentado em 2nd ASPIC International Congress, 2016. Peixoto, Andreia. "Antibody-based Therapeutic Strategies in Clinical Trials for Bladder Cancer: A Systematic Review". Trabalho apresentado em Oncology Spring Meeting, 2016. Peixoto, Andreia. "Hypoxia induces bladder cancer cell invasion by antagonizing the extension of protein O-glycosylation". Trabalho apresentado em Oncology Spring Meeting, 2016. Peixoto, Andreia. "Abnormal protein glycosylation and activated PI3K/Akt/mTOR pathway: role in bladder cancer prognosis and targeted therapeutic". 2015. Peixoto, Andreia. "Abnormal glycosylation in Borrmann type Iv gastric cancer: insight for guided therapeutics". Trabalho apresentado em Oncology Spring Meeting, 2015.
Pré-impressão	Andreia Peixoto; Dylan Ferreira; Andreia Miranda; Marta Relvas-Santos; Rui Freitas; Tim S. Veth; Andreia Brandão; et al. "Multilevel Plasticity and Altered Glycosylation Drive Aggressiveness in Hypoxic and Glucose-Deprived Bladder Cancer Cells". 2023. https://doi.org/10.1101/2023.10.21.561355. 10.1101/2023.10.21.561355 Peixoto, Andreia; Freitas, Rui; Ferreira, Dylan; Relvas-Santos, Marta; Paulo, Paula; Cardoso, Marta; Soares, Janine; et al. "Metabolomics, Transcriptomics and Functional Glycomics Reveals Bladder Cancer Cells Plasticity and Enhanced Aggressiveness Facing Hypoxia and Glucose Deprivation". 2021. http://dx.doi.org/10.1101/2021.02.14.431133. 10.1101/2021.02.14.431133

Propriedade Intelectual

Pedido provisório de patente

2022. "Method for cancer detection, prognosis, and therapeutic selection based on short CD44 glycoproteoforms".
Protegido
2022. "CD44 glycoepitopes and chimeric vaccine glycoconjugates for cancer therapy and synthesis methods thereof".
Protegido

Outros

Outra produção

Hypoxia induces bladder cancer cell invasion by antagonizing the extension of protein O-glycosylation. 2015. Peixoto, Andreia. http://ijup.up.pt/2015/.

Atividades

Apresentação oral de trabalho

	Título da apresentação	Nome do evento Anfitrião (Local do evento)
2025/04/07	CD276 immature glycosylation drives colorectal cancer aggressiveness and T-cell-mediated immune escape	IMMUNO-model Workshop: Harmonizing in vivo models of immunotherapy, past, present and future directions of WG Bergen University (Bergen, Noruega)
2023/11/09	Exploring the cancer glycocode for glycovaccines development	1st Young Researcher's day IPO-Porto Research center (Porto, Portugal)
2023/05/12	Hypoxia and glucose deprivation induce bladder cancer cells dormancy and immature glycosylation driving cancer aggressiveness	29th Porto Cancer Meeting i3S-Institute for Research & Innovation in Health (Porto, Portugal)
2023/04/12	Uncovering the Role of Glycosylation in Bladder Cancer Aggressiveness: Insights from the Tumor Microenvironment	IPO-Porto Research Center Scientific Meeting IPO-Porto Research center (Porto, Portugal)
2022/07/12	Metabolomics, Transcriptomics and Functional Glycomics Reveals Bladder Cancer Cells Plasticity and Enhanced Aggressiveness Facing Hypoxia and Glucose Deprivation	30th International Carbohydrate Symposium International Carbohydrate Organisation (Florianópolis, Brasil)
2021/06/17	Unravelling the Bladder tumour microenvironment using the Flow cytometry toolbox.	XVII Congress of the Iberian Society of Cytometry Instituto Português de Oncologia do Porto, Francisco Gentil, E.P.E (Porto, Portugal)
2019/09/04	Exploring the influence of oxygen and glucose on the bladder cancer glycome by cellular O-glycome reporter amplification : insights for targeted therapeutics	13th International Meeting of the Portuguese Carbohydrate Group- GLUPOR13 Instituto de Investigação e Inovação em Saúde -I3s (Porto, Portugal)
2019/04/24	Bladder cancer Glycomics and Glycoproteomics identify GLUT1 and HOMER3 as top-ranked potentially targetable biomarkers	Clinical Biochemistry and Metabolomics Seminars Escola superior de Saúde (Porto, Portugal)
2019/03/27	Exploring the influence of oxygen and glucose on the bladder cancer glycome by cellular O-glycome reporter amplification: insights for targeted therapeutics.	8th Mass spectrometry and Carbohydrates Workshop University of Aveiro (Aveiro, Portugal)
2018/07/14	Hypoxia enhances the malignant nature of bladder cancer cells and concomitantly antagonizes protein O-glycosylation extension	29th International Carbohydrate Symposium- ICS2018 Faculty of Sciences of the University of Lisbon (Lisboa, Portugal)
2018/06/12	The sweet and sour of protein glycosylation in bladder cancer: setting milestones for clinical applications	Biotechnology Seminars School of Health Sciences - Polytechnic of Porto (Porto, Portugal)
2017/09/11	Hypoxia enhances the malignant nature of badder cancer cells and concomitantly antagonizes protein O-glycosylation extension	12ª reunião do Grupo de Glúcidos- GLUPOR12 Sociedade Portuguesa de Química (Aveiro, Portugal)
2015/05/13	Hypoxia induces bladder cancer cell invasion by antagonizing the extension of protein O-glycosylation	IJUP- Encontro de Investigação Jovem na Universidade do Porto Reitoria da Universidade do Porto (Porto, Portugal)
2015/03/20	Changes in protein glycosylation: biological implications for bladder cancer progression and dissemination	Biochemistry in Health Seminars School of Health Sciences - Polytechnic of Porto (Porto, Portugal)

Orientação

	Título / Tema Papel desempenhado	Curso (Tipo) Instituição / Organização
2024/09/01 - 2025/09/01	Deciphering the Influence of CD276 glycocode in Colorectal Cancer Immunoregulation Orientador	DEGREE IN BIOCHEMISTRY IN HEALTH (Mestrado) Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
2024/02/04 - 2025/02/04	GlycoGuard: Glycophenotyping Early Signs of Gastric Cancer Towards Life Saving Interventions Coorientador de Beatriz Marinho Santos	LPCC- Norte-2024 (Outra) Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
2024/01/01 - 2024/07/15	Tumor Microenvironment and Aberrant Glycosylation: A partnership driving immune escape. Orientador de Sara Francisca Ribeiro Freitas	MEDICINAL BIOTECHNOLOGY (Licenciatura/Bacharelato) School of Health Polytechnic Institute of Porto, Portugal
2022/09/12 - 2023/11/12	Functional glycoproteomics caracterization of gastric cancer cells expressing immature O-glycans Orientador de Martina Dourado Gonçalves	Master Degree in Oncology (Mestrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2022/09/12 - 2023/11/12	Functional glycoproteomics characterization of gastric cancer cells expressing selectin ligands Coorientador de Beatriz Marinho Santos	Master Degree in Oncology (Mestrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2022/01/01 - 2022/12/31	glycoINSPIRER: PRE-CLINICAL VALIDATION OF A GLYCOCODE-INSPIRED VACCINE FOR BLADDER CANCER IMMUNOTHERAPY (under the LPCC-NRN 2022 grant funding) Orientador de Andreia Rafaela Linhares Miranda	Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
2021/09/01 - 2022/12/12	CD44 glycovaccine for Bladder Cancer: synthesis, pre-clinical validation and biotechnological solutions thereof Coorientador de Eduardo da Silva Ferreira	Master in Biochemistry (Mestrado) Universidade de Aveiro, Portugal
2020/09/18 - 2022/02/18	Decoding the Crosstalk Between Dendritic Cells and Bladder Cancer Associated Glycans: A Way to Identify Novel Immunotherapy Targets Coorientador de Andreia Rafaela Linhares Miranda	Master in Medicine and Molecular Oncology (Mestrado) Universidade do Porto Faculdade de Medicina, Portugal

Organização de evento

	Nome do evento Tipo de evento (Tipo de participação)	Instituição / Organização
2025/02/01 - 2026/02/01	Organization of a series of 13 Workshops on Transferable skills for researchers, including topics on Public speaking and presentation techniques; Research integrity; Scientific writing; Grant writing (covering CV and motivational letters writing); Teamwork and collective intelligence / Leadership skills; Creativity for researchers (Science communication for broader audiences; creativity exercises); Scientific graphic design; Well-being and resilience (how to deal with & help others); Time management & life design. (2025/02/01 - 2026/02/01) Oficina (workshop) (Coorganizador)	Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal

Participação em evento

	Descrição da atividade Tipo de evento	Nome do evento Instituição / Organização
2023/05/11 - 2023/05/12	29th Porto Cancer Meeting- Glycosylation in tumour Biology and its clinical implications I The Cancer bittersweet portrait Simpósio	29th Porto Cancer Meeting Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2022/07/10 - 2022/07/15	The International Carbohydrate Symposium is an important forum for researchers involved in all aspects of carbohydrates and a biennial event that was held in Brazil. Simpósio	30th International Carbohydrate Symposium (ICS2022) International Carbohydrate Organisation, Austrália
2021/06/14 - 2021/06/18	XVII Congress of the Iberian Society of Cytometry Congresso	XVII Congress of the Iberian Society of Cytometry Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
2021/06/16 - 2021/06/16	CarboMet Webinar Encontro	CarboMet Meeting
2021/05/27 - 2021/05/29	4th METABOLISM & CANCER SYMPOSIUM Simpósio	4th METABOLISM & CANCER SYMPOSIUM VIRTUAL MEETING
2021/05/20 - 2021/05/21	27th PORTO CANCER MEETING Stemness & Metastasis: Advances in Research and Clinical Translation Encontro	27th PORTO CANCER MEETING Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2021/05/03 - 2021/05/03	International summit to promote and to dynamize European research and innovation in heath collaborative networks to meet the European plan for cancer (Europe's Beating Cancer Plan). Conferência	European Cancer Research Summit 2021 Porto Comprehensive Cancer Center (P.CCC), Portugal
2021/04/29 - 2021/04/29	Participation in the online cycle of conferences in glycosciences promoted by the Grupo Especializado de Hidratos de Carbono de la Real Sociedad Española de Química. Conferência	Conferencias en Glicociencias Grupo Especializado de Hidratos de Carbono (RSEQ) de la Real Sociedad Española de Química, Espanha
2016/03/10 - 2016/03/10	Instructor at the theoretical and practical course of molecular biology applied to oncology. Conferência	1st Precision Oncology Meeting Universidade Fernando Pessoa, Portugal

Júri de grau académico

	Tema Tipo de participação	Nome do candidato (Tipo de grau) Instituição / Organização
2021/07/07	Hematological parameters as prognostic biomarkers in esophageal and gastric cancer. Arguente principal	Paulo Sérgio do Valle (Mestrado) Universidade Fernando Pessoa Faculdade de Ciências da Saúde, Portugal

Arbitragem científica em revista

	Nome da revista (ISSN)	Editora
2023/02/10 - Atual	The Role of Glycosylation on EMT and Mucins in Cancer Development, Diagnostics, and Therapeutics	Frontiers in Molecular Biosciences
2021/11/21 - Atual	Tumor-Associated Glycans and their Receptors on Immune Cells: Sweet-Talking the Security Guards in the Tumor Microenvironment	Frontiers in Molecular Biosciences

Comissão de avaliação

	Descrição da atividade Tipo de assessoria	Instituição / Organização	Entidade financiadora
2020/11/17 - Atual	Invited reviewer of the Journal of Molecular Medicine. Avaliador
2022/09/05 - 2022/09/09	Elsevier book proposal reviewer for the working title "Colorectal Cancer: Disease, Diagnosis and Drug Delivery Approaches" Avaliador	Elsevier Inc, Estados Unidos	Elsevier Inc
2021/07/23 - 2021/07/30	Invited International journal of molecular sciences reviewer Avaliador
2021/06/01 - 2021/06/01	Invited Cells journal reviewer Avaliador
2021/02/20 - 2021/02/27	Invited Cancers journal reviewer Avaliador
2021/02/05 - 2021/02/15	Invited Frontiers Immunology journal reviewer Avaliador
2021/01/20 - 2021/02/11	Invited NWO Open Competition Domain Science M grants reviewer Avaliador	Nederlandse Organisatie voor Wetenschappelijk Onderzoek, Países Baixos
2021/01/04 - 2021/01/10	Invited Frontiers Cell and Developmental Biology journal reviewer Avaliador
2020/11/22 - 2020/11/30	Elsevier book proposal reviewer for the book series "High throughput technologies in disease diagnostics and therapeutics" Avaliador	Elsevier Ltd, Reino Unido	Elsevier Ltd
2020/04/18 - 2020/04/22	Invited Journal of Oncology journal reviewer Avaliador		Hindawi Publishing Corp
2019/11/20 - 2019/11/29	Elsevier proposal reviewer for the book series "Precision Medicine for the Management of Metastatic Cancers"	Elsevier Ltd, Reino Unido

Curso / Disciplina lecionado

	Disciplina	Curso (Tipo)	Instituição / Organização
2019/02/10 - 2019/06/01	Integrated Laboratory Practice II	(Licenciatura)	Polytechnic Institute of Porto - School of Health, Portugal
2019/03/01 - 2019/04/30	Molecular and Celular Therapy	Pathological Anatomy Master Degree (Mestrado)	School of Heath Polytechnic Institute of Porto, Portugal

Expedição científica

	Descrição da atividade	Instituição / Organização
2021/11/01 - 2021/11/10	Participated in the EPIC-XS project "Phosphoproteomics of Hypoxic and Glucose-Deprived Bladder Cancer Cells: The Missing Link Towards Systems Oncology." I developed and optimized advanced proteomics and phosphoproteomics workflows for the analysis of bladder cancer cell models under hypoxic and glucose-deprived conditions at the Netherlands Proteomics Center. This experience enhanced my technical expertise in mass spectrometry-based proteomics and contributed to the project’s goal of elucidating signaling pathways relevant to systems oncology.	Netherlands Proteomics Centre, Países Baixos

Membro de associação

	Nome da associação	Tipo de participação
2024/11/18 - Atual	COST Action CA21135 IMMUNO-model	member
2023/10/01 - Atual	Raquel Seruca Immuno-Oncology Club	member

Tutoria

	Tópico	Nome do aluno
2022/02/14 - 2022/06/03	Laboratory and clinical practice training	Martina Dourado Gonçalves
2022/02/14 - 2022/06/03	Laboratory and clinical practice training	Beatriz Marinho Santos

Distinções

Outra distinção

2023	Individual Call to Scientific Employment Stimulus - 6th Edition Fundação para a Ciência e a Tecnologia, Portugal
2022	Call for R&D Projects in All Scientific Domains - 2022 Fundação para a Ciência e a Tecnologia, Portugal
2015	PhD Scholarship Fundação para a Ciência e a Tecnologia, Portugal
2014	Merit scholarship and diploma for exceptional academic performance Universidade do Porto, Portugal