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Miguel Brito. Completed the Título de Agregado in Habiliation in the field of Biology, specializing in Genetics. (Agergação) in 2017 by Universidade de Lisboa Faculdade de Ciências, Doutoramento in Biologia in 1998 by Universidade de Lisboa, Doutoramento in Biologia in 1997/01/02 by Fundação da Faculdade de Ciências da Universidade de Lisboa, Licenciatura in Nutrition and Dietetics in 2012 by Instituto Politécnico de Lisboa Escola Superior de Tecnologia da Saúde de Lisboa and Licenciatura in Biologia in 1992 by Universidade de Lisboa Faculdade de Ciências. Is Main Coordinator Teacher in Instituto Politécnico de Lisboa Escola Superior de Tecnologia da Saúde de Lisboa, Professor Coordenador com Agregação in Instituto Politécnico de Lisboa Escola Superior de Tecnologia da Saúde de Lisboa, Coordinating Researcher in Centro de Investigação em Saúde e Tecnologia (H&TRC) and Coordinating Researcher in Centro de investigação em Saúde de Angola (CISA). Published 135 articles in journals. Has 6 section(s) of books and 1 book(s). Supervised 3 PhD thesis(es). Supervised 2 MSc dissertation(s). Has received 3 awards and/or honors. Participates and/or participated as Co-Principal Investigator (Co-PI) in 2 project(s) and Principal investigator in 7 project(s). Works in the area(s) of Natural sciences with emphasis on Biological Sciences with emphasis on Genetics and Heredity, Medical and Health Sciences with emphasis on Medical Biotechnology with emphasis on Gene-based Diagnostics and Therapeutic Interventions and Medical and Health Sciences with emphasis on Health Sciences with emphasis on Epidemiology. In his curriculum Ciência Vitae the most frequent terms in the context of scientific, technological and artistic-cultural output are: <i>OGG1<; i> polymorphism; Comet assay; DNA damage; antineoplastic drugs; biomonitoring<b><; b>; occupational exposure; Adult; Carcinogens; Carcinogens: toxicity; Case-Control Studies; Cytostatic Agents; Cytostatic Agents: toxicity; DNA Damage; DNA Damage: drug effects; Female; Fluorouracil; Fluorouracil: toxicity; Humans; Lymphocytes; Lymphocytes: drug effects; Lymphocytes: metabolism; Male; Micronucleus Tests; Middle Aged; Nurses; Occupational Exposure; Occupational Exposure: adverse effects; Portugal; Young Adult; Adrenal Cortex Hormones; Adrenal Cortex Hormones: therapeutic use; Age Factors; Anti-Inflammatory Agents; Anti-Inflammatory Agents: therapeutic use; Antibodies; Monoclonal; Monoclonal: therapeutic use; Azathioprine; Azathioprine: therapeutic use; Colitis; Ulcerative; Ulcerative: genetics; Ulcerative: immunology; Ulcerative: therapy; Gastrointestinal Agents; Gastrointestinal Agents: therapeutic use; Genetic Predisposition to Disease; Infliximab; Mesalamine; Mesalamine: therapeutic use; Phenotype; Polymorphism; Single Nucleotide; Receptors; Interleukin; Interleukin: genetics; Retrospective Studies; Risk Factors; Severity of Illness Index; Treatment Outcome; drug; g6pd deficiency; hemolytic anemia; malaria; Aldehyde Oxidoreductases; Aldehyde Oxidoreductases: genetics; Biological Markers; Biological Markers: analysis; DNA Repair; DNA Repair: genetics; DNA-Binding Proteins; DNA-Binding Proteins: genetics; Environmental Monitoring; Formaldehyde; Formaldehyde: toxicity; Gene Frequency; Genetic Association Studies; Genotype; Logistic Models; Lymphocytes: cytology; Micronuclei; Chromosome-Defective; Chromosome-Defective: chemically indu; Adiponectin; Adiponectin: blood; Adipose Tissue; Adolescent; Bariatric Surgery; Body Composition; Diet; Dietary Carbohydrates; Dietary Carbohydrates: pharmacology; Interleukin-6; Interleukin-6: blood; Micronutrients; Micronutrients: administration {\&; Alternative Splicing; Alternative Splicing: genetics; Breast Neoplasms; Breast Neoplasms: genetics; Breast Neoplasms: metabolism; Cell Line; Tumor; Gene Expression Regulation; Enzymologic; Protein Isoforms; Protein Isoforms: genetics; RNA Splicing; Reverse Transcriptase Polymerase Chain Reaction; cdc25 Phosphatases; cdc25
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Identificação

Identificação pessoal

Nome completo
Miguel Brito
Género
Masculino

Nomes de citação

  • Brito, Miguel

Identificadores de autor

Ciência ID
231F-F341-7E93
ORCID iD
0000-0001-6394-658X

Endereços de correio eletrónico

  • miguel.brito@estesl.ipl.pt (Profissional)

Websites

Domínios de atuação

  • Ciências Naturais - Ciências Biológicas - Genética e Hereditariedade
  • Ciências Médicas e da Saúde - Biotecnologia Médica - Diagnóstico e Terapias de Base Genética
  • Ciências Médicas e da Saúde - Ciências da Saúde - Epidemiologia
Formação
Grau Classificação
2017
Concluído
 Habiliation in the field of Biology, specializing in Genetics. (Agergação) (Título de Agregado)
Universidade de Lisboa Faculdade de Ciências, Portugal
"Agregação no ramo de Biologia, especialidade de Genética" (TESE/DISSERTAÇÃO)
 unanimidade
2008 - 2012
Concluído
 Nutrition and Dietetics (Licenciatura)
Instituto Politécnico de Lisboa Escola Superior de Tecnologia da Saúde de Lisboa, Portugal
"Dietetica e Nutrição" (TESE/DISSERTAÇÃO)
 16
1998
Concluído
 Biologia (Doutoramento)
Especialização em Especialidade: Ecologia e Biossistemática
Universidade de Lisboa, Portugal
"Estudo da Estrutura Genética e da Diferenciação de Populações Portuguesas de Leuciscus e de Chondrostoma Polylepis: (pisces: Cyprinidae)" (TESE/DISSERTAÇÃO)
1997/01/02
Concluído
 Biologia (Doutoramento)
Especialização em Especialidade: Ecologia e Biossistemática
Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal
1987 - 1992
Concluído
 Biologia (Licenciatura)
Universidade de Lisboa Faculdade de Ciências, Portugal
 Distinção e Louvor por unanimidade
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento		 Empregador
2018/01/01 - Atual Investigador Coordenador (carreira) (Investigação) Centro de Investigação em Saúde e Tecnologia (H&TRC) , Portugal
Centro de Investigação em Saúde e Tecnologia (H&TRC) , Portugal
2012/08/01 - Atual Investigador Coordenador (carreira) (Investigação) Centro de investigação em Saúde de Angola (CISA), Angola
Centro de investigação em Saúde de Angola (CISA), Angola

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento		 Empregador
2018/01/04 - Atual Professor Coordenador Principal (Docente Ensino Superior Politécnico) Instituto Politécnico de Lisboa Escola Superior de Tecnologia da Saúde de Lisboa, Portugal
2016 - 2019 Professor Coordenador (Docente Ensino Superior Politécnico) Instituto Politécnico de Lisboa, Portugal
2016 - 2019 Professor Coordenador (Docente Ensino Superior Politécnico) Instituto Politécnico de Lisboa, Portugal
2017/09/01 - 2018/01/03 Professor Coordenador (Docente Ensino Superior Politécnico) Instituto Politécnico de Lisboa Escola Superior de Tecnologia da Saúde de Lisboa, Portugal
1999/11/02 - 2018/01/03 Professor Adjunto (Docente Ensino Superior Politécnico) Instituto Politécnico de Lisboa Escola Superior de Tecnologia da Saúde de Lisboa, Portugal
2016 - 2018 Professor Coordenador (Docente Ensino Superior Politécnico) Instituto Politécnico de Lisboa, Portugal
2016 - 2018 Professor Coordenador (Docente Ensino Superior Politécnico) Instituto Politécnico de Lisboa, Portugal
2016 - 2018 Professor Coordenador (Docente Ensino Superior Politécnico) Instituto Politécnico de Lisboa, Portugal
2016 - 2018 Professor Coordenador (Docente Ensino Superior Politécnico) Instituto Politécnico de Lisboa, Portugal
1999/10/01 - 2016/08/31 Professor Adjunto (Docente Ensino Superior Politécnico) Instituto Politécnico de Lisboa Escola Superior de Tecnologia da Saúde de Lisboa, Portugal
2013 - 2016 Professor Adjunto (Docente Ensino Superior Politécnico) Instituto Politécnico de Lisboa Escola Superior de Tecnologia da Saúde de Lisboa, Portugal
2013 - 2016 Professor Adjunto (Docente Ensino Superior Politécnico) Instituto Politécnico do Porto Instituto Superior de Engenharia do Porto, Portugal
2013 - 2016 Professor Adjunto (Docente Ensino Superior Politécnico) Instituto Politécnico de Lisboa Escola Superior de Tecnologia da Saúde de Lisboa, Portugal
2013 - 2016 Professor Adjunto (Docente Ensino Superior Politécnico) Instituto Politécnico de Lisboa Escola Superior de Tecnologia da Saúde de Lisboa, Portugal
2013 - 2016 Professor Adjunto (Docente Ensino Superior Politécnico) Instituto Politécnico de Lisboa Escola Superior de Tecnologia da Saúde de Lisboa, Portugal
2013 - 2016 Professor Adjunto (Docente Ensino Superior Politécnico) Instituto Politécnico de Lisboa Escola Superior de Tecnologia da Saúde de Lisboa, Portugal
1999/01/09 - 2003/07/25 Professor Coordenador (Docente Ensino Superior Politécnico) Escola Superior de Educação de Almeida Garrett, Portugal

Cargos e Funções

Categoria Profissional
Instituição de acolhimento		 Empregador
2022 - 2023 Conselho científico/técnico-científico ou orgão correspondente Instituto Politécnico de Lisboa, Portugal
2021 - 2022 Conselho científico/técnico-científico ou orgão correspondente Instituto Politécnico de Lisboa, Portugal
2020 - 2021 Conselho científico/técnico-científico ou orgão correspondente Instituto Politécnico de Lisboa, Portugal
2019 - 2020 Conselho científico/técnico-científico ou orgão correspondente Instituto Politécnico de Lisboa, Portugal
2018 - 2019 Conselho científico/técnico-científico ou orgão correspondente Instituto Politécnico de Lisboa, Portugal
2017 - 2019 Conselho científico/técnico-científico ou orgão correspondente Instituto Politécnico de Lisboa, Portugal
2017 - 2018 Conselho científico/técnico-científico ou orgão correspondente Instituto Politécnico de Lisboa, Portugal
2016 - 2018 Coordenação ou direção de centro de investigação, departamento ou equivalente Instituto Politécnico de Lisboa, Portugal
2016 - 2018 Coordenação ou direção de centro de investigação, departamento ou equivalente Instituto Politécnico de Lisboa, Portugal
2016 - 2018 Coordenação ou direção de centro de investigação, departamento ou equivalente Instituto Politécnico de Lisboa, Portugal
2016 - 2018 Coordenação ou direção de centro de investigação, departamento ou equivalente Instituto Politécnico de Lisboa, Portugal
2016 - 2018 Coordenação ou direção de centro de investigação, departamento ou equivalente Instituto Politécnico de Lisboa, Portugal
2016 - 2018 Coordenação ou direção de centro de investigação, departamento ou equivalente Instituto Politécnico de Lisboa, Portugal

Outros

Categoria Profissional
Instituição de acolhimento		 Empregador
2018/01/04 - Atual Professor Coordenador com Agregação Instituto Politécnico de Lisboa Escola Superior de Tecnologia da Saúde de Lisboa, Portugal
1999/09/01 - 2002/05/01 Investigador convidado Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
1995/06/01 - 1999/10/30 Tecnico superior de Medicina Legal Instituto Nacional de Medicina Legal e Ciências Forenses Delegação do Sul, Portugal
1992/10/01 - 1995/06/06 Bolseiro de Doutoramento Universidade de Lisboa Faculdade de Ciências, Portugal
Projetos

Bolsa

Designação Financiadores
2022/02/01 - 2024/10/31 African Research and Innovative Initiative for Sickle cell Education: Improving Research Capacity for Service Improvement
H2020-MSCA-RISE-2018 (Marie Sktodoska-Curie Research Innovation Staff Exchange)
Co-Investigador Responsável (Co-IR)
Centro de Investigação em Saúde e Tecnologia (H&TRC) , Portugal
 European Union
Em curso
2022/09/01 - 2023/09/01 Deteção de microorganismos intestinais patogénicos em crianças angolanas com anemia falciforme
IDI&CA-ParasitesSCD
Investigador responsável
Centro de Investigação em Saúde e Tecnologia (H&TRC) , Portugal
 Instituto Politécnico de Lisboa
Em curso
2021/04/01 - 2022/04/01 Surveillance of sickle cell disease pregnant women. Prevention of Cerebral Vascular Accidents in Angola
Fundação Calouste Gulbenkian, Camões IP
Investigador responsável
Centro de Investigação em Saúde e Tecnologia (H&TRC) , Portugal
 Fundação Calouste Gulbenkian
Em curso
2018/11/01 - 2022/03/31 Sickle Cell Anemia and Fetal Hemoglobin. Genetic modifiers in an Angolan Children Cohort
FCT/Aga Khan (project n°330842553)
Investigador responsável
Centro de Investigação em Saúde e Tecnologia (H&TRC) , Portugal
 Aga Khan Foundation
Concluído
2020/09/01 - 2022/03/06 Ocular repercussions in COVID-19 patients: microbiota and structural changes of the retina and choroid
IDI&CA
Co-Investigador Responsável (Co-IR)
Centro de Investigação em Saúde e Tecnologia (H&TRC) , Portugal
 Instituto Politécnico de Lisboa
Concluído
2020/05/01 - 2021/05/01 Characterization of microbiotic profile in patients with COVID-19. Potential severity risk score and therapeutic targets
IPL
Investigador responsável
Centro de Investigação em Saúde e Tecnologia (H&TRC) , Portugal
 Instituto Politécnico de Lisboa
Concluído
2019/09/01 - 2020/08/31 Natural compounds potential for ¿-globin gene expression reactivation and Fetal Hemoglobin induction, InVitro approach
IDI&CA/IPL-HemoFet
Investigador responsável
Centro de Investigação em Saúde e Tecnologia (H&TRC) , Portugal
 Instituto Politécnico de Lisboa
Concluído
2018/09/01 - 2019/08/31 SCITelomer - Smoking cessation intervention: influence on telomere length
IDI&CA/IPL
Investigador responsável
Centro de Investigação em Saúde e Tecnologia (H&TRC) , Portugal
 Instituto Politécnico de Lisboa
Concluído
2017/05 - 2018/12 “Estudo da Obesidade Monogénica em jovens com recurso á utilização de tecnologias de ponta – “Next Generation Sequencing”.
IPL/2017/GenetObese/ESTeSL
 Instituto Politécnico de Lisboa
2016/12 - 2018/12 “Tecnologias de sequenciação de nova geração aplicadas à saúde: na fronteira da genómica humana”
LISBOA-07-5674-FEDER-000001
 por-lisboa
2016/11 - 2018/06 Deficiência em Micronutrientes em crianças de idade Pré-escolar. Método de Quantificação Laboratorial”
IPL/2016/MicroNut_ESTeSL
 Instituto Politécnico de Lisboa
2014/04 - 2018/05 Eficácia de uma intervenção baseada no consumo alimentar no estado nutricional e na deficiência em micronutrientes em crianças com menos de cinco anos, em Angola.”
CISA 04/2014
 BP Plc
2014/02 - 2017/08 High resolution ecological mapping of filarial vectors
BMGF:03011000026
 Bill and Melinda Gates Foundation
2013/08 - 2014/12 Estudo dos fatores de risco cardiovasculares numa população adulta da Província do Bengo, Angola – Prevalência e Incidência da Hipertensão Arteria
CISA -05/2013
 Fundação Calouste Gulbenkian
2007/10 - 2010/12 The genetic control of sex determination in the Squalius alburnoides hybrid complex: new insights into the effects of hybridisation and genome interaction
grant.Provided by PTCRIS: 65586
 Fundação para a Ciência e a Tecnologia
2007/10 - 2010/12 The genetic control of sex determination in the Squalius alburnoides hybrid complex: new insights into the effects of hybridisation and genome interaction
Provided by PTCRIS: 65586
 Fundação para a Ciência e a Tecnologia
2007/05 - 2010/05 The polyglycine expansion in the N-terminal domain of eRF3a in cancer development
grant.Provided by PTCRIS: 67031
 Stichting Weten
2007/05 - 2010/05 The polyglycine expansion in the N-terminal domain of eRF3a in cancer development
Provided by PTCRIS: 67031
 Fundação para a Ciência e a Tecnologia
2006/01 - 2008/12 “Exposição Profissional ao Formaldeído – Contributo para a caracterização da exposição e consequentes efeitos na saúde em trabalhadores de Serviços Hospitalares de Anatomia Patológica”
projeto 075MNA/06
 Instituto para a Segurança, Higiene e Saúde no Trabalho
2005/01 - 2007/12 Interação entre fatores alimentares e polimorfismos genéticos no aparecimento do cancro do cólon e recto: o papel dos genes da via metabólica do ácido fólico e do gene APC”
projeto 68925
 Fundação Calouste Gulbenkian
2002/05 - 2005/04 “The role of polymorphic GGC repeats in gene expression and its association with cancer”
POCTI/MGI/40071/2001
 Fundação da Ciência e Tecnologia
1995/12/01 - 1996/11/30 VARIABILIDADE GENÉTICA DAS POPULAÇÕES PISCÍCOLAS CONTINENTAIS. A INFLUÊNCIA DE ACÇÕES ANTROPOGÉNICAS
PRAXIS XXI/BD/5287/95
Universidade de Lisboa Faculdade de Ciências, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído

Projeto

Designação Financiadores
2020/01/01 - 2023/12/31 Health and Technology Research Center
UIDB/05608/2020
Instituto Politécnico de Lisboa, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2020/01/01 - 2023/12/31 Health and Technology Research Center
UIDP/05608/2020
Instituto Politécnico de Lisboa, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2020/01/01 - 2023/12/31 Health and Technology Research Center
UIDP/05608/2020
10.54499/UIDP/05608/2020
Instituto Politécnico de Lisboa, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2021/01/01 - 2021/07/01 Intervention in Occupational Health: Integrated response in Pandemic COVID19
Câmara Municipal de Lisboa
Investigador responsável
Centro de Investigação em Saúde e Tecnologia (H&TRC) , Portugal
 Camara Municipal de Lisboa
Concluído
2019/01/01 - 2019/12/31 Environmental Health Institute
UID/DTP/04295/2019
Universidade de Lisboa Instituto de Saúde Ambiental, Portugal

Associação para a Investigação e Desenvolvimento da Faculdade de Medicina, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2007/10/26 - 2010/12/31 The genetic control of sex determination in the Squalius alburnoides hybrid complex: new insights into the effects of hybridisation and genome interaction
PTDC/BIA-BDE/65586/2006
Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal

Universidade de Lisboa Faculdade de Ciências, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2007/05/04 - 2010/05/03 The polyglycine expansion in the N-terminal domain of eRF3a in cancer development
PTDC/SAU-GMG/67031/2006
Instituto Politécnico de Lisboa, Portugal

Instituto Politécnico de Lisboa Escola Superior de Tecnologia da Saúde de Lisboa, Portugal

Instituto Politécnico de Coimbra Centro de Estudos de Recursos Naturais Ambiente e Sociedade, Portugal

Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
1995/12/01 - 1996/11/30 VARIABILIDADE GENÉTICA DAS POPULAÇÕES PISCÍCOLAS CONTINENTAIS. A INFLUÊNCIA DE ACÇÕES ANTROPOGÉNICAS
PRAXIS XXI/BD/5287/95
Universidade de Lisboa Faculdade de Ciências, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
Produções

Publicações

Artigo em conferência
  1. Jacques, Filipa; Delgadinho, Mariana; Ginete, Catarina; Gomes, Mário; Ribeiro, Edna; Brito, Miguel; Gomes, Anita Q.. "Effects of methanolic and aqueous Carica Papaya leaf extracts in transcriptional and miRNA-mediated regulation of fetal hemoglobin". 2023.
  2. Tonin, Fernanda; Ginete, Catarina; Ferreira, J.; Delgadinho, Mariana; Fernandez-Llimos, Fernando; Brito, Miguel. "Comparative efficacy and safety of pharmacological interventions for sickle cell disease in children and adolescents: a network meta-analysis". 2023.
    10.1097/01.HS9.0000928488.59931.31
  3. Brito, Miguel; Delgadinho, Mariana; Ginete, Catarina; Santos, Brígida; Vasconcelos, J.. "The gut microbiome and hydroxyurea effect on sickle cell disease children from Angola". 2023.
    10.1097/01.HS9.0000928132.39710.c7
  4. Jacques, Filipa; Canteiro, Beatriz; Mendes, Maria; Delgadinho, Mariana; Oliveira, Ketlyn; Ginete, Catarina; Gomes, Mário; et al. "Effects of methanolic and aqueous Carica Papaya leaf extracts in transcriptional and miRNA-mediated regulation of fetal hemoglobin". 2023.
  5. Canteiro, Beatriz; Mendes, Maria; Jacques, Filipa; Delgadinho, Mariana; Oliveira, Ketlyn; Ginete, Catarina; Gomes, Mário; et al. "Effects of Quercetin in transcriptional and post-transcriptional regulation of fetal hemoglobin". 2023.
  6. Tonin, Fernanda; Ginete, Catarina; Ferreira, J.; Delgadinho, Mariana; Fernandez-Llimos, Fernando; Brito, Miguel. "Comparative efficacy and safety of pharmacological interventions for sickle cell disease in children and adolescents: a network meta-analysis". 2023.
    10.1097/01.HS9.0000928488.59931.31
  7. Canteiro, Beatriz; Mendes, Maria; Jacques, Filipa; Delgadinho, Mariana; Oliveira, Ketlyn; Ginete, Catarina; Gomes, Mário; et al. "Effects of Quercetin in transcriptional and post-transcriptional regulation of fetal hemoglobin". 2023.
  8. Brito, Miguel; Ginete, Catarina; Ferreira, J.; Delgadinho, Mariana; Sebastião, Cruz; Mateus, A.; Mendes, M.; et al. "Preliminary findings from the follow-up of pregnant sickle cell disease patients in Luanda, Angola". 2023.
    10.1097/01.HS9.0000928520.27610.83
  9. Marques, Rira; Paiva, Mariana; Ginete, Catarina; Nolasco, Sofia; Marinho, Susana H.; Veiga, Luisa; Brito, Miguel; Soares, Helena; Carmona, Bruno. "Os cílios primários regulam os níveis de tiorredoxina redutase 1 e de yH2AX em resposta a níveis elevados de glucose". 2023.
  10. Jacques, Filipa; Canteiro, Beatriz; Mendes, Maria; Delgadinho, Mariana; Oliveira, Ketlyn; Ginete, Catarina; Gomes, Mário; et al. "Effects of methanolic and aqueous Carica Papaya leaf extracts in transcriptional and miRNA-mediated regulation of fetal hemoglobin". 2023.
  11. Marques, Rita; Paiva, Mariana; Ginete, Catarina; Nolasco, Sofia; Marinho, Susana H.; Veiga, Luisa; Brito, Miguel; Soares, Helena; Carmona, Bruno. "The nuclear levels of thioredoxin reductase 1, gamma-H2AX, and yap are modulated by primary cilia in response to high glucose levels". 2023.
  12. Brito, Miguel; Delgadinho, Mariana; Ginete, Catarina; Santos, Brígida; Vasconcelos, J.. "The gut microbiome and hydroxyurea effect on sickle cell disease children from Angola". 2023.
    10.1097/01.HS9.0000928132.39710.c7
  13. Jacques, Filipa; Delgadinho, Mariana; Ginete, Catarina; Gomes, Mário; Ribeiro, Edna; Brito, Miguel; Gomes, Anita Q.. "Effects of methanolic and aqueous Carica Papaya leaf extracts in transcriptional and miRNA-mediated regulation of fetal hemoglobin". 2023.
  14. Canteiro, B.; Mendes, M.; Delgadinho, Mariana; Oliveira, K.; Ginete, Catarina; Gomes, M.; Brito, Miguel; Gomes, Anita Q.; Ribeiro, Edna. "Effects of quercetin in transcriptional regulation of fetal hemoglobin". 2022.
    10.1097/01.HS9.0000873164.96343.19
  15. Delgadinho, Mariana; Ginete, Catarina; Fernandes, C.; Santos, Brígida; Vasconcelos, J.; Brito, Miguel. "The effect of hydroxyurea in the gut microbiome of Angolan children with sickle cell disease". 2022.
    10.1097/01.HS9.0000872872.99697.fb
  16. Santos, Brígida; Miranda, Armandina; Ginete, Catarina; Arez, Ana Paula; Faustino, Paula; Brito, Miguel. "Tratamento com Hidroxiureia em crianças com Anemia de Células Falciformes em Angola: caracterização da coorte, evolução clínica e laboratorial". 2022.
  17. Poças, Ilda Maria; Cunha, João Paulo; Camacho, Pedro; Silva, Carina; Ribeiro, Edna; Brito, Miguel; Mendonça, Paula; et al. "Ocular repercussions in COVID-19 patients: structural changes of the retina and choroid". 2022.
  18. Camacho, Pedro; Pereira, Bruno; Ribeiro, Edna; Varandas, Teresa; Henriques, José; Nascimento, João; Dutra-Medeiros, Marco; et al. "Role of DNA methylation in persistent diabetic macular edema". 2022.
  19. Brito, Miguel; Ferreira, J.; Capriello, I.; Ginete, Catarina; Delgadinho, Mariana; Sebastião, Cruz; Mendes, M.; et al. "Genetic variability and disease severity in a cohort of Angolan sickle cell disease patients". 2022.
    10.1097/01.HS9.0000873120.65347.33
  20. Tonin, Fernanda; Ginete, Catarina; Ferreira, Joao; Delgadinho, Mariana; Fernandez-Llimos, Fernando; Brito, Miguel. "Comparative efficacy and safety of pharmacological interventions for managing sickle cell disease complications in children and adolescents: a systematic review with network meta-analyses". 2022.
    10.1016/j.jval.2022.09.224
  21. Brito, Miguel; Ginete, Catarina; Ferreira, Joana; Mendes, Manuela; Vasconcelos, Jocelyne; Delgadinho, Mariana; Sebastião, Cruz; et al. "Pregnancy surveillance in sickle cell disease patients: a cohort study in an African country – Angola". 2022.
    10.1182/blood-2022-159681
  22. Mendes, M.; Canteiro, Beatriz; Delgadinho, Mariana; Oliveira, Ketlyn; Ginete, Catarina; Gomes, Mário; Ribeiro, Edna; Brito, Miguel; Gomes, Anita Q.. "Effects of Carica papaya leaf extracts in transcriptional regulation of fetal hemoglobin". 2022.
    10.1097/01.HS9.0000873252.25768.51
  23. Camacho, Pedro; Pereira, Bruno; Ribeiro, Edna; Varandas, T.; Henriques, J.; Nascimento, J.; Dutra-Medeiros, M.; et al. "DNA methylation in diabetic macular edema: first report". 2022.
  24. Canteiro, B.; Mendes, M.; Delgadinho, Mariana; Oliveira, K.; Ginete, Catarina; Gomes, M.; Brito, Miguel; Gomes, Anita Q.; Ribeiro, Edna. "Effects of quercetin in transcriptional regulation of fetal hemoglobin". 2022.
    10.1097/01.HS9.0000873164.96343.19
  25. Camacho, Pedro; Pereira, Bruno; Ribeiro, Edna; Varandas, T.; Henriques, J.; Nascimento, J.; Dutra-Medeiros, M.; et al. "DNA methylation in diabetic macular edema: first report". 2022.
  26. Tonin, Fernanda; Ginete, Catarina; Ferreira, Joao; Delgadinho, Mariana; Fernandez-Llimos, Fernando; Brito, Miguel. "Comparative efficacy and safety of pharmacological interventions for managing sickle cell disease complications in children and adolescents: a systematic review with network meta-analyses". 2022.
    10.1016/j.jval.2022.09.224
  27. Camacho, Pedro; Poças, Ilda Maria; Cunha, João Paulo; Silva, Carina; Ribeiro, Edna; Brito, Miguel; Mendonça, Paula; et al. "Alterações na coroide, retina e nervo ótico subsequentes a COVID-19". 2022.
  28. Mendes, M.; Canteiro, Beatriz; Delgadinho, Mariana; Oliveira, Ketlyn; Ginete, Catarina; Gomes, Mário; Ribeiro, Edna; Brito, Miguel; Gomes, Anita Q.. "Effects of Carica papaya leaf extracts in transcriptional regulation of fetal hemoglobin". 2022.
    10.1097/01.HS9.0000873252.25768.51
  29. Delgadinho, Mariana; Ginete, Catarina; Fernandes, C.; Santos, Brígida; Vasconcelos, J.; Brito, Miguel. "The effect of hydroxyurea in the gut microbiome of Angolan children with sickle cell disease". 2022.
    10.1097/01.HS9.0000872872.99697.fb
  30. Camacho, Pedro; Pereira, Bruno; Ribeiro, Edna; Varandas, Teresa; Henriques, José; Nascimento, João; Dutra-Medeiros, Marco; et al. "Role of DNA methylation in persistent diabetic macular edema". 2022.
  31. Germano, Isabel; Santos, Brígida; Delgadinho, Mariana; Lopes, Pedro; Arez, Ana Paula; Brito, Miguel; Faustino, Paula. "Genetic Modulators of Hemolytic Anemia in Angolan Children with Sickle Cell Anemia". 2021.
  32. Gonçalves, Mauer; Pedro, João Almeida; Silva, Carina; Magalhães, Pedro; Brito, Miguel. "Normal values of the electrocardiogram in Angolans". 2021.
  33. Santos, Brígida; Miranda, Armandina; Ginete, Catarina; Arez, Ana Paula; Faustino, Paula; Brito, Miguel. "Avaliação clínica da resposta ao tratamento com Hidroxiureia em crianças com Anemia de Células Falciformes em Angola". 2021.
  34. Santos, Brígida; Delgadinho, Mariana; Ginete, Catarina; Ferreira, Joana; Arez, Ana Paula; Faustino, Paula; Brito, Miguel. "Modificadores Genéticos da Anemia de Células Falciformes em Crianças Angolanas". 2021.
  35. Delgadinho, Mariana; Santos, Brígida; Brito, Miguel. "Haplotype distribution and genotypic diversity among Angolan children with sickle cell disease". 2021.
    10.1097/MD.0000000000023585
  36. Germano, Isabel; Santos, Brígida; Delgadinho, Mariana; Lopes, Pedro; Arez, Ana Paula; Brito, Miguel; Faustino, Paula. "Genetic modulators of hemolytic anemia in Angolan children with sickle cell anemia". 2021.
    10.1097/MD.0000000000029313
  37. Brito, Miguel; Delgadinho, Mariana; Ginete, Catarina; Mendes, Joana; Vasconcelos, J.; Santos, Brígida. "Gut microbiota impact on Angolan children with sickle cell disease". 2020.
  38. Brito, Miguel; Santos, Brígida; Delgadinho, Mariana; Panzo, Miguel; Catumbela, Lucas; Salvador, Graciete; Valentim, Isabel; et al. "The role of alpha-thalassemia in Sickle Cell Disease phenotype in Angolan pediatric patients". 2020.
  39. Santos, Brígida; Germano, Isabel; Delgadinho, Mariana; Ginete, Catarina; Arez, Ana Paula; Faustino, Paula; Brito, Miguel. "Biomarcadores e moduladores genéticos da Anemia Falciforme numa coorte de crianças Angolanas com Anemia Falciforme". 2020.
  40. Veríssimo, Carolina; Santos, Margarida; Brito, Miguel; Veiga, Luísa. "Oxytocin and mental health in college students". 2019.
  41. Serrasqueiro, Bernardo; Veiga, Luísa; Silva-Nunes, José; Brito, Miguel. "The use of next-generation sequencing in the study of monogenic obesity". 2019.
  42. Tchonhi, Chissengo; Borges, Eliana; Amorim, António; Prata, Maria João; Brito, Miguel. "Newborn screening of hemoglobinopathies in Bengo, Angola". 2019.
  43. Brito, Miguel; Tchonhi, Chissengo. "Protection against malaria in heterozygous girls for G6PD deficiency in Angola". 2019.
    10.4269/ajtmh.abstract2019
  44. Fançony, Claudia; Soares, Ania; Brito, Miguel. "Effectivity of wash/malaria educational community-based intervention in reducing anemia among preschool children from Bengo, Angola". 2019.
    10.4269/ajtmh.abstract2019
  45. Arrais, Margarete; Lulua, Ofélia; Quifica, Francisca; Gama, Jorge; Taborda-Barata, Luis; Brito, Miguel. "Allergic sensitisation and relationship with asthma and other allergic diseases in children in the province of Bengo, Angola". 2019.
    10.1183/13993003.congress-2019.PA4500
  46. Matos, Elisabete; Sousa, Daniela; Delgadinho, Mariana; Mateus, Vanessa; Silva, Inês; Ribeiro, Edna; Brito, Miguel. "Potencial da genisteína na reativação da expressão do gene da ¿-globulina e indução da hemoglobina fetal". 2019.
  47. Brito, Miguel; Azevedo, Patrícia; Coelho, André; Veiga, Luisa; Costa-Veiga, Ana. "Tobacco smoking have no influence on buccal telomere length among Portuguese master students". 2019.
  48. Arrais, Margarete; Sachicola, Ofélia; Quifica, Francisca; Gama, Jorge; Taborda-Barata, Luis; Brito, Miguel. "Lack of association between asthma, atopy and helminthic infection in school-age children in the province of Bengo, Angola". 2019.
    10.1183/13993003.congress-2019.PA2738
  49. Sousa, Daniela; Matos, Elisabete; Delgadinho, Mariana; Ribeiro, Edna; Mateus, Vanessa; Silva, Inês; Brito, Miguel. "O potencial da epigalocatequina-3-galato na reativação da expressão da y-globina e indução da hemoglobina fetal". 2019.
  50. Santos, Brígida; Jeremias, Ilda; Panzo, Miguel; Catumbela, Lucas; salvador, Graciete; Valentim, Isabel; Zagi, Félix; et al. "Caracterização de um coorte de crianças com anemia de células falciformes em Angola". 2019.
  51. Serrasqueiro, Bernardo; Veiga, Luísa; Silva-Nunes, José; Brito, Miguel. "A utilização da ‘Next-Generation Sequencing’ no estudo da obesidade monogénica". 2018.
  52. Brito, Miguel; Serrasqueiro, Bernardo; Veiga, Luísa; Silva-Nunes, José. "Monogenic obesity in Portugal: the use of next generation sequencing (preliminary results)". 2018.
  53. Brito, Miguel; Tchonhi, Chissengo. "Malaria in children and G6PD deficiency in an endemic area for malaria in Bengo province, Angola". 2018.
  54. Pádua, Mário; Santos, Sofia; Brito, Miguel. "Deficiência em micronutrientes em crianças de idade pré-escolar: método de quantificação laboratorial". 2018.
  55. Coutinho, Filipa; Pinto, Jéssica; Brito, Miguel; Veiga, Luísa. "Influência da obesidade, dieta e exercício físico no comprimento dos telómeros". 2018.
  56. Silva-Nunes, José; Brito, Miguel; Silva, Carina; Oliveira, Ana Cebola; Veiga, Luísa. "Unacylated ghrelin does not seem to influence glucose homeostasis in obese women". 2017.
    10.1530/endoabs.49.EP451
  57. Brito, Miguel; Tamayo, Sara; Fançony, Cláudia; Soares, Ânia. "Prevalence and determinants of under and overnutrition among under five children in Bengo Province, Angola". 2017.
  58. Brito, Miguel; Soares, A.; Fançony, C.; Martins, A.; Gasparinho, C.; Nery, S.; Mirante, C.; et al. "Determinants of malnutrition among under-fives in Bengo province, Angola". 2015.
    10.1111/tmi.12574
  59. Ladeira, Carina; Viegas, Susana; Pádua, Mário; Carolino, Elisabete; Gomes, Manuel; Brito, Miguel. "Comet assay as a human biomonitoring tool: application in occupational exposure to antineoplastic drugs". 2015.
    10.3389/conf.fgene.2015.01.00019
  60. Ladeira, Carina; Viegas, Susana; Carolino, Elisabete; Gomes, Manuel C.; Brito, Miguel. "Selenium role in an human biomonitoring study applied to occupational health". 2015.
  61. Silva-Nunes, José; Brito, Miguel; Veiga, Luísa. "Insulin resistance does not play a major role in lipid and apolipoprotein profile in obese women". 2015.
    10.1530/endoabs.37.EP643
  62. Ladeira, Carina; Viegas, Susana; Carolino, Elisabete; Gomes, Manuel C.; Brito, Miguel. "Micronutrients intake associated with DNA damage assessed by in a human biomonitoring study". 2015.
    10.3389/conf.fgene.2015.01.00012
  63. Allan, F.; Sousa-Figueiredo, J. C.; Paulo, R.; Emery, A. M.; Mirante, C.; Sebastião, A.; Luciano, A.; et al. "Mapping freshwater snails in Angola: distribution, identity and molecular diversity of medically important taxa". 2015.
  64. Rosário, Edite; Brito, Miguel. "Sistema de autópsia verbal no Dande, província do Bengo". 2014.
  65. Fançony, Cláudia; Brito, Miguel. "Transição epidemiológica no norte de Angola: discussão dos resultados cumulativos do CISA (Centro de Investigação em Saúde de Angola)". 2014.
  66. Rosário, Edite; Brito, Miguel. "Implementação de um sistema de autópsia verbal no município do Dande, província do Bengo". 2014.
  67. Lemos, Manuel; Moura, Sofia; Brito, Miguel. "Uso de redes mosquiteiras em crianças menores de 5 anos, numa zona rural de Angola". 2014.
  68. Rosário, Edite; Pedro, João de Almeida; Brito, Miguel. "Aplicação de sistemas de vigilância demográfica e informação geográfica na investigação em saúde". 2014.
  69. Veiga, Luísa; Brito, Miguel; Oliveira, Ana; Silva, Carina; Silva-Nunes, José. "Desacyl-ghrelin does not influence insulin sensitivity". 2014.
  70. Fançony, Cláudia; Moura, Sofia; Mirante, Clara; Neves, Marcela; Bernardino, Luís; Sambo, Rosário; Brito, Miguel. "Impacto de uma formação na qualidade do diagnóstico microscópico de malária em Angola". 2014.
  71. Brito, Miguel; Tchonhi, Chissengo Lucama; Mayer, Carlos; Reis, Ana; Deus, Inês; Clemente, Isabel. "Epidemiologia das hemoglobinopatias: variabilidade genética da hemoglobina e de enzimas eritrocitárias no Hospital Provincial do Bengo, Caxito, Angola". 2014.
  72. Ladeira, Carina; Viegas, Susana; Carolino, Elisabete; Gomes, M. C.; Brito, Miguel. "Biomonitorization in hospital settings with cytostatics occupational exposure". 2014.
  73. Fançony, Cláudia; Pedro, João Mário; Brito, Miguel. "Epidemiologic transition in northern Angola: discussion of cumulative results from CISA (Health Research Centre of Angola)". 2014.
  74. Brito, Miguel; Lemos, Manuel; Mirante, Clara; Moura, Sofia; Mayer, Carlos. "Effect of deworming on hemoglobin concentration in children from 2 to 15 years from the Bengo Province, Angola". 2014.
  75. Ladeira, Carina; Viegas, Susana; Carolino, Elisabete; Gomes, M. C.; Brito, Miguel. "Application of alkaline comet assay in human biomonitoring for genotoxicity: a study on occupational exposure to cytostatics". 2014.
  76. Lemos, Manuel; Sousa, Carlos Alberto Pinto de; Moura, Sofia; Mirante, Clara; Brito, Miguel. "Efectividade do controlo da schistosomíase no Bengo". 2014.
  77. Brito, Miguel; Reis, Ana; Tchonhi, Chissengo; Clemente, Isabel; Deus, Inês; Mayer, Carlos. "Resultados preliminares do rastreio neonatal de doenças das células falciformes no Hospital Geral do Bengo, Caxito, Angola". 2014.
  78. Pedro, João de Almeida; Mayer, António Carlos; Brito, Miguel; Barros, Henrique. "Tendências dos factores de risco cardiovascular em Angola: um estudo prospectivo numa população adulta, entre 2011 e 2013". 2014.
  79. Ladeira, Carina; Viegas, Susana; Carolino, Elisabete; Gomes, M. C.; Brito, Miguel. "Cytostatics occupational exposure: genotoxic effects assessment". 2014.
  80. Oliveira, Ana; Gasparinho, Carolina; Mayer, António Carlos; Ribeiro, Natália; Brito, Miguel. "Sistema de vigilância de morbilidade pediátrica no Hospital Geral do Bengo". 2014.
  81. Gasparinho, Carolina; Mirante, Clara; Mayer, António Carlos; Brito, Miguel. "Diarreia em crianças menores de cinco anos no Hospital Geral do Bengo". 2014.
  82. Gasparinho, C.; Mirante, M.C.; Lima, S.; Nery, S.; Istrate, C.; Mayer, A. C.; Brito, Miguel. "Estudo dos agentes causais de diarreia em crianças menores de 5 anos no Hospital Geral do Bengo". 2014.
  83. Moura, S.; Fançony, Cláudia; Mirante, Clara; Neves, M.; Bernardino, L.; Sambo, R.; Barros, H.; Brito, Miguel. "Diagnóstico da malária em Angola: um país em estreita ligação com Portugal". 2014.
  84. Gasparinho, Carolina; Mirante, Maria Clara; Lima, Sónia; Nery, Susana Vaz; Istrate, Cláudia; Mayer, António Carlos; Brito, Miguel. "Aetiology of diahrroea in children under five at the Bengo General Hospital, Angola". 2014.
  85. Ladeira, Carina; Gomes, M. G.; Brito, Miguel. "XRCC3 THR241MET polymorphism influence on nuclear buds frequency in exposed to formaldehyde". 2011.
  86. Ladeira, Carina; Gomes, Manuel C.; Brito, Miguel. "Genotoxicity biomarkers in occupational to formaldehyde in pathology anatomy laboratories". 2011.
  87. Ladeira, Carina; Gomes, Manuel C.; Brito, Miguel. "Lifestyle factors influence in the frequency in buccal micronucleus". 2011.
  88. Ladeira, Carina; Gomes, Manuel C.; Brito, Miguel. "XRCC3241 Polymorphism influence on genotoxicity biomarkers frequency in workers occupationaly exposed to formaldehyde". 2011.
  89. Ladeira, Carina; Gomes, Manuel C.; Brito, Miguel. "Effects of exposure to formaldehyde and tobacco smoking on genotoxicity biomarkers". 2011.
  90. Ladeira, Carina; Gomes, Manuel C.; Brito, Miguel. "Evaluation of the influence of the ADH3 ILE349VAL polymorphism in the frequency of genotoxicity biomarkers in workers exposed to formaldehyde and tobacco smoking". 2011.
  91. Ladeira, Carina; Viegas, Susana; Gomes, Manuel C.; Brito, Miguel. "Effects of age and gender on peripheral lymphocyte micronucleus". 2011.
  92. Ladeira, Carina; Viegas, Susana; Carolino, Elisabete; Prista, João; Gomes, Manuel C.; Brito, Miguel. "Exposição profissional a formaldeído em laboratórios de anatomia patológica: que realidade em Portugal?". 2011.
  93. Ladeira, Carina; Viegas, Susana; Prista, J.; Gomes, Manuel C.; Brito, Miguel. "Formaldehyde's genotoxicity effects in pathology anatomy technologists and medical pathologists". 2011.
  94. Ladeira, Carina; Viegas, Susana; Carolino, Elisabete; Gomes, Manuel C.; Brito, Miguel. "Polimorfismos genéticos no gene XRCC3 e dano no DNA em trabalhadores expostos ocupacionalmente a formaldeído". 2011.
  95. Ladeira, Carina; Viegas, Susana; Prista, João; Malta-Vacas, Joana; Gomes, Mário; Mendonça, Paula; Brito, Miguel; et al. "Micronuclei in peripheral blood lymphocytes in formaldehyde occupationally exposed workers". 2011.
    10.1016/j.toxlet.2009.06.448
  96. Ladeira, Carina; Gomes, Manuel C.; Brito, Miguel. "Interaction of formaldehyde and tobacco smoking in the frequency of micronucleus and the XRCC3 Thr241Met polymorphism". 2010.
    Ladeira C, Gomes MC, Brito M. Interaction of formaldehyde and tobacco smoking in the frequency of micronucleus and the XRCC3 Thr241Met polymorphism. In 8th International Symposium on Biological Monitoring in Occupational and Environmental Health, Finland,
  97. Ladeira, Carina; Viegas, Susana; Carolino, Elisabete; Prista, João; Gomes, Manuel C.; Brito, Miguel. "Effects of the interaction of tobacco smoke and alcohol consumption on buccal micronucleus in workers exposed occupationally to formaldehyde". 2010.
  98. Ladeira, Carina; Viegas, Susana; Nunes, Carla; Malta-Vacas, Joana; Gomes, Mário; Mendonça, Paula; Prista, João; Gomes, Manuel C.; Brito, Miguel. "Occupational exposure to formaldehyde: effects of years of exposure in the frequency of micronucleus". 2010.
  99. Viegas, Susana; Ladeira, Carina; Nunes, Carla; Malta-Vacas, Joana; Gomes, Mário; Mendonça, Paula; Prista, João; et al. "Risk assessment in occupational exposure to formaldehyde: differences between anatomy and pathology laboratories and formaldehyde-resins production". 2010.
    10.1016/j.toxlet.2010.03.260
  100. Viegas, Susana; Ladeira, Carina; Nunes, Carla; Malta-Vacas, Joana; Gomes, Mário; Brito, Miguel; Mendonça, Paula; Prista, João. "Occupational exposure to formaldehyde in anatomy and pathology laboratories: differences between exposure groups?". 2010.
  101. Brito, Miguel; Ferreira, Paula; Guerreiro, Catarina Sousa; Malta-Vacas, Joana; Tavares, L.; Santos, P.; Pinto, A.; Cravo, Marília. "Ecosapentanoic acid (EPA) does not affect cell kinetics in peripheral lymphocites from patients with Crohn's disease (CD) according to IL6 174G/C polymorphism". 2008.
    DOI:10.1016/S1744-1161(08)70119-4
Artigo em revista
  1. Sandra Miranda; Fernanda S. Tonin; Carlos Pinto-Sousa; Elsa Fortes-Gabriel; Miguel Brito. "Genetic Profile of Rotavirus Type A in Children under 5 Years Old in Africa: A Systematic Review of Prevalence". Viruses (2024): https://doi.org/10.3390/v16020243.
    10.3390/v16020243
  2. Mariana Delgadinho; Luísa Veiga; Catarina Ginete; Brígida Santos; Armandina Miranda; Jocelyne Neto de Vasconcelos; Miguel Brito. "Differential expression of adhesion molecules in sickle cell anemia and gut microbiome effect". Annals of Hematology (2024): https://doi.org/10.1007/s00277-023-05589-5.
    10.1007/s00277-023-05589-5
  3. Gonçalves, Mauer; Pedro, João Mário; Silva, Carina; Magalhães, Pedro; Brito, Miguel. "Influence of cigarette smoking on the Index of Cardiac Electrophysiological Balance in apparently healthy Angolans". (2024): http://hdl.handle.net/10400.21/16751.
    10.21542/gcsp.2024.5
  4. Santos, Brígida; Ginete, Catarina; Gonçalves, Elisângela; Delgadinho, Mariana; Miranda, Armandina; Faustino, Paula; Arez, Ana Paula; Brito, Miguel. "Characterization of a cohort of Angolan children with sickle cell anemia treated with hydroxyurea". (2024): http://hdl.handle.net/10400.21/16872.
    10.1016/j.bcmd.2023.102822
  5. Catarina Ginete; Mariana Delgadinho; Brígida Santos; Vera Pinto; Carina Silva; Armandina Miranda; Miguel Brito. "Are Genetic Modifiers the Answer to Different Responses to Hydroxyurea Treatment?—A Pharmacogenetic Study in Sickle Cell Anemia Angolan Children". International Journal of Molecular Sciences (2023): https://doi.org/10.3390/ijms24108792.
    10.3390/ijms24108792
  6. Ana Rita Mira; Ana Sofia Zeferino; Raquel Inácio; Mariana Delgadinho; Miguel Brito; Cecília R. C. Calado; Edna Ribeiro. "Epigenetic and Drug Response Modulation of Epigalocaten-In-3-Gallate in Staphylococcus aureus with Divergent Resistance Phenotypes". Antibiotics (2023): https://doi.org/10.3390/antibiotics12030519.
    10.3390/antibiotics12030519
  7. Fernanda S Tonin; Catarina Ginete; Fernando Fernandez-Llimos; Joana Ferreira; Mariana Delgadinho; Miguel Brito; Fernanda S. Tonin; Brígida Santos. "Efficacy and safety of pharmacological interventions for managing sickle cell disease in children and adolescents: protocol for a systematic review with network meta-analysis". BMJ Open (2023): https://doi.org/10.1136/bmjopen-2022-064872.
    10.1136/bmjopen-2022-064872
  8. Canteiro, Beatriz; Mendes, Maria; Jacques, Filipa; Delgadinho, Mariana; Oliveira, Ketlyn; Ginete, Catarina; Gomes, Mário; et al. "Effects of quercetin in transcriptional and post-transcriptional regulation of fetal hemoglobin". (2023): http://hdl.handle.net/10400.21/16390.
    10.1109/ENBENG58165.2023.10175363
  9. Canteiro, Beatriz; Mendes, Maria; Delgadinho, Mariana; Oliveira, Ketlyn; Ginete, Catarina; Gomes, Mário; Ribeiro, Edna; Brito, Miguel; Gomes, Anita Q.. "Análise do efeito biológico de extratos de folhas de Carica papaya na viabilidade e na proliferação de células K562". (2023): http://hdl.handle.net/10400.21/16397.
    10.25758/set.663
  10. Arrais, Margarete; Dias, Welwitschia; Silva, Maura; Neto, Luquenia; Pedro, Naiol; Jungo, Sónia; Miguel, Avelina; et al. "Clinical characteristics and variables associated with COVID-19 morbidity and mortality in Luanda, Angola, in the first year of the pandemic". (2023): http://hdl.handle.net/10400.21/16963.
    10.4314/ahs.v23i4.9
  11. NCD Risk Factor Collaboration; Brito, Miguel. "Diminishing benefits of urban living for children and adolescents' growth and development". (2023): http://hdl.handle.net/10400.21/15908.
    10.1038/s41586-023-05772-8
  12. Almeida, Priscilla; Costa, Alcina; Seuanes, Filomena; Romão, Raquel; Brito, Miguel; Silva, Isabel Moreira da; Miranda, Armandina. "Anemia de células falciformes: avaliação da hemoglobina fetal num grupo de crianças angolanas antes e após tratamento com hidroxiureia". (2023): http://hdl.handle.net/10400.18/8751.
  13. Canteiro, Beatriz; Mendes, Maria; Delgadinho, Mariana; Oliveira, Ketlyn; Ginete, Catarina; Gomes, Mário; Ribeiro, Edna; Brito, Miguel; Gomes, Anita. "Analysis of the biological effect of Carica papaya leaf extracts on the viability and proliferation of K562 cells". (2023): https://doi.org/10.25758/set.663.
    https://doi.org/10.25758/set.663
  14. Camacho, Pedro; Ribeiro, Edna; Pereira, Bruno; Varandas, Teresa; Nascimento, João; Henriques, José; Dutra-Medeiros, Marco; et al. "DNA methyltransferase expression (DNMT1, DNMT3a and DNMT3b) as a potential biomarker for anti-VEGF diabetic macular edema response". (2023): http://hdl.handle.net/10362/154460.
    https://doi.org/10.1177/11206721231171623
  15. Savonius, Okko; Souza, Cintia F. de; Fançony, Cláudia; Cruzeiro, Manuel Leite; Brito, Miguel; Pelkonen, Tuula. "PCR-confirmed malaria among children presenting with a decreased level of consciousness in Angola: a prospective, observational study". (2023): http://hdl.handle.net/10400.21/15937.
    10.1186/s12936-023-04556-9
  16. Arrais, Margarete L.; Maricoto, Tiago; Lulua, Ofélia M.; Quifica, Francisca G.; Gama, Jorge M.; Brito, Miguel; Taborda-Barata, Luis. "Factors associated with poor asthma symptom control in adult Angolan regularly seen at an outpatient respiratory clinic". (2023): http://hdl.handle.net/10400.21/16644.
    10.4314/ahs.v23i3.78
  17. Mariana Delgadinho; Catarina Ginete; Brígida Santos; Joana Mendes; Armandina Miranda; Jocelyne Vasconcelos; Miguel Brito. "Microbial gut evaluation in an angolan paediatric population with sickle cell disease". Journal of Cellular and Molecular Medicine (2022): https://doi.org/10.1111/jcmm.17402.
    10.1111/jcmm.17402
  18. Mauer A. A. Gonçalves; João Mário Pedro; Carina Silva; Pedro Magalhães; Miguel Brito. "Electrocardiographic findings in pregnant women in Angola". Annals of Noninvasive Electrocardiology (2022): https://doi.org/10.1111/anec.12980.
    10.1111/anec.12980
  19. Mariana Delgadinho; Catarina Ginete; Brígida Santos; Carolina Fernandes; Carina Silva; Armandina Miranda; Jocelyne Neto de Vasconcelos; Miguel Brito. "How Hydroxyurea Alters the Gut Microbiome: A Longitudinal Study Involving Angolan Children with Sickle Cell Anemia". International Journal of Molecular Sciences (2022): https://doi.org/10.3390/ijms23169061.
    10.3390/ijms23169061
  20. Edna Ribeiro; Mariana Delgadinho; Elisabete Matos; Raquel Santos; Daniela Sousa; Heloísa Galante; Miguel Brito. "Epigenetic and Transcriptional Modulator Potential of Epigallocatechin-3-gallate and Genistein on Fetal Hemoglobin Reactivators Genes". Clinical Complementary Medicine and Pharmacology 2 2 (2022): 100034-100034. https://doi.org/10.1016/j.ccmp.2022.100034.
    10.1016/j.ccmp.2022.100034
  21. Mauer A.A. Gonçalves; João Mário Pedro; Carina Silva; Pedro Magalhães; Miguel Brito. "Prevalence of major and minor electrocardiographic abnormalities and their relationship with cardiovascular risk factors in Angolans". IJC Heart & Vasculature 39 (2022): 100965-100965. https://doi.org/10.1016/j.ijcha.2022.100965.
    10.1016/j.ijcha.2022.100965
  22. Cláudia Fançony; Ânia Soares; João Lavinha; Miguel Brito; Fançony, Cláudia; Soares, Ânia; Lavinha, João; Brito, Miguel. "Zinc Deficiency Interacts with Intestinal/Urogenital Parasites in the Pathway to Anemia in Preschool Children, Bengo–Angola". Nutrients 14 7 (2022): 1392-1392. https://doi.org/10.3390/nu14071392.
    10.3390/nu14071392
  23. Margarete Arrais; Welwitschia Dias; Jorge M R Gama; Miguel Brito. "Physicians’ perceptions of their knowledge and the preparedness of health facilities in Angola to diagnose and manage COVID-19". International Health (2022): https://doi.org/10.1093/inthealth/ihab017.
    10.1093/inthealth/ihab017
  24. Sebastião, Cruz S.; Neto, Zoraima; Jandondo, Domingos; Mirandela, Marinela; Morais, Joana; Brito, Miguel. "Dengue virus among HIV-infected pregnant women attending antenatal care in Luanda, Angola: an emerging public health concern". (2022): http://hdl.handle.net/10400.21/14957.
    10.1016/j.sciaf.2022.e01356
  25. Nobre, José Guilherme; Delgadinho, Mariana; Silva, Carina; Mendes, Joana; Mateus, Vanessa; Ribeiro, Edna; Costa, Diogo Alpuim; et al. "Gut microbiota profile of COVID-19 patients: prognosis and risk stratification (microCOVID-19 study)". (2022): http://hdl.handle.net/10400.21/15150.
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  28. Zeferino, Ana Sofia; Mira, Ana Rita; Delgadinho, Mariana; Brito, Miguel; Ponte, Tomás; Ribeiro, Edna. "Drug resistance and epigenetic modulatory potential of epigallocatechin-3-gallate against Staphylococcus aureus". (2022): http://hdl.handle.net/10400.21/14566.
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  33. Germano, Isabel; Santos, Brígida; Delgadinho, Mariana; Ginete, Catarina; Lopes, Pedro; Arez, Ana Paula; Brito, Miguel; Faustino, Paula. "Genetic modulation of anemia severity, hemolysis level, and hospitalization rate in Angolan children with sickle cell anemia". (2022): http://hdl.handle.net/10451/54444.
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  34. Zhou, Bin; Carrillo-Larco, Rodrigo M.; Danaei, Goodarz; Riley, Leanne M.; Paciorek, Christopher J.; Stevens, Gretchen A.; Gregg, Edward W.; et al. "Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants". (2022): http://hdl.handle.net/11449/218864.
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  35. Germano, Isabel; Santos, Brígida; Delgadinho, Mariana; Ginete, Catarina; Lopes, Pedro; Arez, Ana Paula; Brito, Miguel; Faustino, Paula. "Genetic modulation of anemia severity, hemolysis level, and hospitalization rate in Angolan children with Sickle Cell Anemia". (2022): http://hdl.handle.net/10400.18/8427.
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  36. Germano, Isabel; Santos, Brígida; Delgadinho, Mariana; Ginete, Catarina; Lopes, Pedro; Arez, Ana Paula; Brito, Miguel; Faustino, Paula. "Genetic modulation of anemia severity, hemolysis level, and hospitalization rate in Angolan children with Sickle Cell Anemia". (2022): http://hdl.handle.net/10362/143842.
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  37. Germano, Isabel; Santos, Brígida; Delgadinho, Mariana; Ginete, Catarina; Lopes, Pedro; Arez, Ana Paula; Brito, Miguel; Faustino, Paula. "Genetic modulation of anemia severity, hemolysis level, and hospitalization rate in Angolan children with sickle cell anemia". (2022): http://hdl.handle.net/10400.21/14974.
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  38. Cruz S. Sebastião; Paolo Parimbelli; Manuela Mendes; Euclides Sacomboio; Joana Morais; Jocelyne Neto de Vasconcelos; Miguel Brito. "Prevalence and Risk Factors of SARS-CoV-2 Infection among Parturients and Newborns from Luanda, Angola". Pathogens 10 11 (2021): 1494-1494. https://doi.org/10.3390/pathogens10111494.
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  39. Miguel Brito; Mauer Gonçalves; João Mário Pedro; Carina Silva; Pedro Magalhães. "Prevalence of atrial fibrillation in Bengo Province, Angola: Results from a population-based study". RevSALUS - Revista Científica da Rede Académica das Ciências da Saúde da Lusofonia (2021): https://doi.org/10.51126/revsalus.v3i2.146.
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  40. Carla Viegas; Raquel Pimenta; Marta Dias; Bianca Gomes; Miguel Brito; Liliana Aranha Caetano; Elisabete Carolino; Anita Quintal Gomes. "Microbiological Contamination Assessment in Higher Education Institutes". Atmosphere (2021): https://doi.org/10.3390/atmos12081079.
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  41. Margarete Arrais; Ofélia Lulua; Francisca Quifica; José Rosado-Pinto; Jorge M. R. Gama; Philip J. Cooper; Luis Taborda-Barata; Miguel Brito. "Lack of Consistent Association between Asthma, Allergic Diseases, and Intestinal Helminth Infection in School-Aged Children in the Province of Bengo, Angola". International Journal of Environmental Research and Public Health 18 11 (2021): 6156-6156. https://doi.org/10.3390/ijerph18116156.
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  42. Mariana Delgadinho; Catarina Ginete; Brígida Santos; Armandina Miranda; Miguel Brito. "Genotypic Diversity among Angolan Children with Sickle Cell Anemia". International Journal of Environmental Research and Public Health 18 10 (2021): 5417-5417. https://doi.org/10.3390/ijerph18105417.
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  43. Carolina Gasparinho; Aguinaldo Kanjungo; Félix Zage; Isabel Clemente; Ana Santos-Reis; Miguel Brito; José Carlos Sousa-Figueiredo; Filomeno Fortes; Luzia Gonçalves. "Impact of Annual Albendazole Versus Four-Monthly Test-and-Treat Approach of Intestinal Parasites on Children Growth—A Longitudinal Four-Arm Randomized Parallel Trial during Two Years of a Community Follow-Up in Bengo, Angola". Pathogens 10 3 (2021): 309-309. https://doi.org/10.3390/pathogens10030309.
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  44. Cruz S. Sebastião; Joana Morais; Miguel Brito. "Factors Influencing HIV Drug Resistance among Pregnant Women in Luanda, Angola: Findings from a Cross-Sectional Study". Tropical Medicine and Infectious Disease (2021): https://doi.org/10.3390/tropicalmed6010029.
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  45. Sebastião, Cruz S.; Morais, Joana; Brito, Miguel. "Clinical and public health implications of HIV-genetic diversity and drug resistance mutations in Angola: a systematic review". (2021): http://hdl.handle.net/10400.21/12423.
    10.24875/AIDSRev.20000057
  46. Rosário, Edite Vila Nova; Severo, Milton; Francisco, Diogo; Brito, Miguel; Costa, Diogo. "Examining the relation between the subjective and objective social status with health reported needs and health-seeking behaviour in Dande, Angola". (2021): http://hdl.handle.net/10400.21/13432.
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  47. Gonçalves, Mauer A. A.; Pedro, João Mário; Silva, Carina; Magalhães, Pedro; Brito, Miguel. "Prevalência de fibrilhação auricular na Província do Bengo, Angola: resultados de um estudo de base populacional". (2021): http://hdl.handle.net/10400.21/14102.
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  48. Fançony, Cláudia; Soares, Ânia; Lavinha, João; Barros, Henrique; Brito, Miguel. "Effectiveness of nutrition and WASH/malaria educational community-based interventions in reducing anemia in children from Angola". (2021): http://hdl.handle.net/10400.21/13099.
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  49. Alpuim Costa, Diogo; Gonçalves Nobre, José Guilherme; Batista, Marta Vaz; Ribeiro, Catarina; Calle, Catarina; Cortes, Alfonso; Marhold, Maximilian; et al. "Human microbiota and breast cancer : is there any relevant link? A literature review and new horizons toward personalised medicine". (2021): http://hdl.handle.net/10451/46987.
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  52. Brígida Santos; Mariana Delgadinho; Joana Ferreira; Isabel Germano; Armandina Miranda; Ana Paula Arez; Paula Faustino; Miguel Brito. "Co-Inheritance of alpha-thalassemia and sickle cell disease in a cohort of Angolan pediatric patients". Molecular Biology Reports 47 7 (2020): 5397-5402. https://doi.org/10.1007/s11033-020-05628-8.
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  53. Paulo, R.; Brito, M.; Van-Dunem, P.; Martins, A.; Novak, R.J.; Jacob, B.; Molyneux, D.M.; et al. "Clinical, serological and DNA testing in Bengo Province, Angola further reveals low filarial endemicity and opportunities for disease elimination". Parasite Epidemiology and Control 11 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85092320755&partnerID=MN8TOARS.
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  90. {Miguel Brito,; Brito, Miguel; Tchonhi, Chissengo Lucama; Santos, Brígida; Veiga, Luísa. "Glucose-6-Phosphate Dehydrogenase Deficiency in Children from 0 to 14 Years Hospitalized at the Pediatric Hospital David Bernardino, Luanda, Angola". Journal of Pharmacogenomics & Pharmacoproteomics 05 02 (2014): 2-5. http://omicsonline.org/open-access/glucosephosphate-dehydrogenase-deficiency-in-children-at-the-pediatric-hospital-in-angola-2153-0645-5-125.php?aid=24577.
    10.4172/2153-0645.1000125
  91. Cravo, Marilia; Ferreira, Paula; Sousa, Patricia; Moura-Santos, Paula; Velho, Sonia; Tavares, Lurdes; Deus, Joao Ramos; et al. "Clinical and genetic factors predicting response to therapy in patients with Crohn's disease". United European Gastroenterology Journal 2 1 (2014): 47-56. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000347773700007&KeyUID=WOS:000347773700007.
    10.1177/2050640613519626
  92. Silva-Nunes, Jos{\'{e. "Factors related with adiponectinemia in obese and normal-weight women and with its variation in weight loss programs.". Obesity facts 6 2 (2013): 124-33. http://www.ncbi.nlm.nih.gov/pubmed/23571643.
    10.1159/000350664
  93. Carlos, F{\'{a; Carlos, Fabio Ferreira; Silva-Nunes, Jose; Flores, Orfeu; Brito, Miguel; Doria, Goncalo; Veiga, Luisa; Baptista, Pedro Viana. "Association of FTO and PPARG polymorphisms with obesity in Portuguese women.". Diabetes, metabolic syndrome and obesity : targets and therapy 6 (2013): 241-5. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3712741{\&}tool=pmcentrez{\&}rendertype=abstract.
    10.2147/DMSO.S45779
  94. Brito, M.; Lemos, M.; Mirante, C.; Moura, S.. "Preliminary results from an intervention study in children aged 2-16 years in controlling Schistosomiasis in a village from Bengo Province (Angola)". Tropical Medicine & International Health 18 (2013): 123-123. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000324029000331&KeyUID=WOS:000324029000331.
  95. Viegas, S.; Ladeira, C.; Gomes, M.; Nunes, C.; Brito, M.; Prista, J.; Viegas, Susana; et al. "Exposure and genotoxicity assessment methodologies - the case of formaldehyde occupational exposure". Current Analytical Chemistry 9 3 (2013): 476-484. http://www.scopus.com/inward/record.url?eid=2-s2.0-84878663847&partnerID=MN8TOARS.
    10.2174/1573411011309030017
  96. Moura, Luis M; Faria, Susana; Brito, Miguel; Pinto, Fausto J; Kristensen, Steen D; Barros, Isabel M; Rajamannan, Nalini; et al. "Relationship of PON1 192 and 55 gene polymorphisms to calcific valvular aortic stenosis.". American journal of cardiovascular disease 2 2 (2012): 123-32. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3371627{\&}tool=pmcentrez{\&}rendertype=abstract.
  97. Viegas, Susana; Teixeira, Joao; Brito, Miguel; Viegas, Carla. "Current Research Issues in Occupational and Environmental Exposure in Portugal and Europe". Journal of Toxicology and Environmental Health-Part a-Current Issues 75 22-23 (2012): 1315-1315. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000311992700001&KeyUID=WOS:000311992700001.
    10.1080/15287394.2012.721162
  98. Veiga, Lu{\'{\i; Veiga, Luisa; Silva-Nunes, Jose; Melao, Alice; Oliveira, Ana; Duarte, Leone; Brito, Miguel; et al. "Q192R polymorphism of the paraoxonase-1 gene as a risk factor for obesity in Portuguese women.". European journal of endocrinology / European Federation of Endocrine Societies 164 2 (2011): 213-8. http://www.ncbi.nlm.nih.gov/pubmed/21078685.
    10.1530/EJE-10-0825
  99. Lakhwani, S.; Raya, J.M.; González-Brito, G.; Álvarez-Argüelles, H.; Brito, M.L.; Hernández-Nieto, L.. "Reversible bone marrow necrosis after all-trans retinoic acid induction therapy for acute promyelocytic leukaemia". Pathology 43 5 (2011): 515-517. http://www.scopus.com/inward/record.url?eid=2-s2.0-80052118370&partnerID=MN8TOARS.
    10.1097/PAT.0b013e3283489087
  100. Silva-Nunes, J.; Duarte, L.; Oliveira, A.; Melao, A.; Brito, M.; Veiga, L.. "Adiponectinaemia, metabolic status, insulin secretion and insulin resistance in obese women: influence of weight loss". Diabetologia 54 (2011): S302-S302. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000307671301402&KeyUID=WOS:000307671301402.
  101. Cravo, Mar{\'{\i. "Risk factors for metabolic bone disease in Crohn's disease patients.". Inflammatory bowel diseases 16 12 (2010): 2117-24. http://www.ncbi.nlm.nih.gov/pubmed/20848459.
    10.1002/ibd.21297
  102. Alves, Margarida; Carreira, Isabel; Liberato, Paulo; Ramos, S{\^{a; Alves, M.; Carreira, I.; Liberato, P.; et al. "Identification of a 0.4 Kb deletion region in 10q26 associated with endometrial carcinoma.". Oncology reports 23 2 (2010): 519-22. http://www.ncbi.nlm.nih.gov/pubmed/20043116.
    10.3892/or-00000664
  103. Viegas, Susana; Ladeira, Carina; Nunes, Carla; Malta-Vacas, Joana; Gomes, Mario; Brito, Miguel; Mendonca, Paula; Prista, Joao. "Genotoxic effects in occupational exposure to formaldehyde: A study in anatomy and pathology laboratories and formaldehyde-resins production.". Journal of occupational medicine and toxicology (London, England) 5 1 (2010): 25-25. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2933706{\&}tool=pmcentrez{\&}rendertype=abstract.
    10.1186/1745-6673-5-25
  104. Ladeira, C.; Gomes, M. C.; Brito, M.. "ADH3 Ile349Val polymorphism influence on genotoxicity biomarkers frequency in workers occupationally exposed to formaldehyde". Ejc Supplements 8 5 (2010): 29-29. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000288603100110&KeyUID=WOS:000288603100110.
  105. Ladeira, C.; Viegas, S.; Prista, J.; Gomes, M. C.; Brito, M.. "Effects of age and gender on peripheral lymphocyte micronucleus". Ejc Supplements 8 5 (2010): 30-30. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000288603100111&KeyUID=WOS:000288603100111.
  106. Ladeira, C.; Gomes, M. C.; Brito, M.. "Lifestyle factors influence in the frequency in buccal micronucleus". Ejc Supplements 8 5 (2010): 20-20. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000288603100074&KeyUID=WOS:000288603100074.
  107. Moura, L. M.; Ramos, S.; Rocha-Goncalves, F.; Brito, M.; Zamorano, J.; Barros, I.; Rajamannan, N.. "The SNP Gln192Arg of the paraoxonase 1 (PON1) gene is Associated with the progression of the Calcific Aortic Valve Disease". European Heart Journal 31 (2010): 863-863. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000281531905500&KeyUID=WOS:000281531905500.
  108. Ladeira, C.; Gomes, M. C.; Brito, M.. "XRCC3 Thr241Met polymorphism influence on genotoxicity biomarkers frequency in workers occupationally exposed to formaldehyde". Ejc Supplements 8 5 (2010): 20-20. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000288603100073&KeyUID=WOS:000288603100073.
  109. Malta-Vacas, Joana; Ferreira, Paula; Monteiro, Carolino; Brito, Miguel. "Differential expression of GSPT1 GGCn alleles in cancer.". Cancer genetics and cytogenetics 195 2 (2009): 132-42. http://www.ncbi.nlm.nih.gov/pubmed/19963113.
    10.1016/j.cancergencyto.2009.08.010
  110. Guerreiro, Catarina Sousa; Ferreira, Paula; Tavares, Lourdes; Santos, Paula Moura; Neves, Manuela; Brito, Miguel; Cravo, Mar{\'{\i. "Fatty acids, IL6, and TNFalpha polymorphisms: an example of nutrigenetics in Crohn's disease.". The American journal of gastroenterology 104 9 (2009): 2241-9. http://www.ncbi.nlm.nih.gov/pubmed/19550417.
    10.1038/ajg.2009.313
  111. Malta-Vacas, Joana; Nolasco, Sofia; Monteiro, Carolino; Soares, Helena; Brito, Miguel. "Translation termination and protein folding pathway genes are not correlated in gastric cancer.". Clinical chemistry and laboratory medicine 47 4 (2009): 427-31. http://www.ncbi.nlm.nih.gov/pubmed/19284299.
    10.1515/CCLM.2009.091
  112. Malta-Vacas, Joana; Chauvin, Celine; Goncalves, Lucilia; Nazare, Antonia; Carvalho, Carlos; Monteiro, Carolino; Bagrel, Denyse; et al. "eRF3a/GSPT1 12-GGC allele increases the susceptibility for breast cancer development". Oncology Reports 21 6 (2009): 1551-1558. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000266185900027&KeyUID=WOS:000266185900027.
    10.3892/or_00000387
  113. Silva-Nunes, J.; Duarte, L.; Veiga, L.; Melao, A.; Brito, M.; Malheiro, F.. "Blood pressure levels and dipping pattern are determined by insulin resistance independently from fat mass and adiponectin interaction in premenopausal obese women". Diabetologia 52 (2009): S429-S429. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000269262401097&KeyUID=WOS:000269262401097.
  114. Guerreiro, Catarina Sousa; Carmona, Bruno; Gon{\c{c; Goncalves, Susana; Carolino, Elisabete; Fidalgo, Paulo; Brito, Miguel; Leitao, Carlos Nobre; Cravo, Marilia. "Risk of colorectal cancer associated with the C677T polymorphism in 5,10-methylenetetrahydrofolate reductase in Portuguese patients depends on the intake of methyl-donor nutrients.". The American journal of clinical nutrition 88 5 (2008): 1413-8. http://www.ncbi.nlm.nih.gov/pubmed/18996879.
    10.3945/ajcn.2008.25877
  115. Carmona, Bruno; Guerreiro, Catarina; Cravo, Marilia; Nobre-Leitao, Carlos; Brito, Miguel. "5 ' and 3 ' UTR thymidylate synthase polymorphisms modulate the risk of colorectal cancer independently of the intake of methyl group donors". Molecular Medicine Reports 1 5 (2008): 747-752. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000261058200023&KeyUID=WOS:000261058200023.
    10.3892/mmr_00000023
  116. Moura, Luis; Zamorano, Jose; Ramos, Sandra; Brito, Miguel; Veiga, Luisa; Roche-Gonzalves, F.; Rajamannan, Nalini M.. "PON1 genotype correlates with increased risk of aortic stenosis progression". Journal of the American College of Cardiology 51 10 (2008): A276-A276. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000253997102092&KeyUID=WOS:000253997102092.
  117. Machado, P.; Raya, J.M.; Martín, T.; Morabito, L.; Brito, M.L.; Rodríguez-Martín, J.M.. "Successful response to rituximab in two cases of acquired haemophilia refractory to standard-therapy". International Journal of Hematology 87 5 (2008): 545-549. http://www.scopus.com/inward/record.url?eid=2-s2.0-46149105198&partnerID=MN8TOARS.
    10.1007/s12185-008-0077-4
  118. Raya Sánchez, J.M.; Ruano, J.A.; Bosch, J.M.; Golvano, E.; Molero, T.; Lemes, A.; Cuesta, J.; Brito, M.L.; Hernández-Nieto, L.. "Splenic marginal zone lymphoma - A clinicopathological study in a series of 16 patients". Hematology 13 5 (2008): 276-281. http://www.scopus.com/inward/record.url?eid=2-s2.0-55849113313&partnerID=MN8TOARS.
    10.1179/102453308X316068
  119. Conde, Ana R; Martins, Ana P; Brito, Miguel; Manuel, Armandina; Ramos, S{\^{a; Conde, Ana R.; Martins, Ana P.; et al. "DMBT1 is frequently downregulated in well-differentiated gastric carcinoma but more frequently upregulated across various gastric cancer types.". International journal of oncology 30 6 (2007): 1441-6. http://www.ncbi.nlm.nih.gov/pubmed/17487364.
  120. Guerreiro, C.S.; Cravo, M.L.; Brito, M.; Vidal, P.M.; Fidalgo, P.O.; Leitão, C.N.; Guerreiro, Catarina S.; et al. "The D1822V APC polymorphism interacts with fat, calcium, and fiber intakes in modulating the risk of colorectal cancer in Portuguese persons". American Journal of Clinical Nutrition 85 6 (2007): 1592-1597. http://www.scopus.com/inward/record.url?eid=2-s2.0-34250028725&partnerID=MN8TOARS.
  121. Brito, M; Malta-Vacas, J; Carmona, B; Aires, C; Costa, P; Martins, A P; Ramos, S; Conde, A R; Monteiro, C. "Polyglycine expansions in eRF3/GSPT1 are associated with gastric cancer susceptibility.". Carcinogenesis 26 12 (2005): 2046-9. http://www.ncbi.nlm.nih.gov/pubmed/15987717.
    10.1093/carcin/bgi168
  122. Malta-Vacas, J; Aires, C; Costa, P; Conde, A R; Ramos, S; Martins, A P; Monteiro, C; Brito, M. "Differential expression of the eukaryotic release factor 3 (eRF3/GSPT1) according to gastric cancer histological types.". Journal of clinical pathology 58 6 (2005): 621-5. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1770693{\&}tool=pmcentrez{\&}rendertype=abstract.
    10.1136/jcp.2004.021774
  123. Goncalves, J.; Malta-Vacas, J.; Louis, M.; Brault, L.; Bagrel, D.; Monteiro, C.; Brito, M.; Gon{\c{c. "Modulation of translation factor's gene expression by histone deacetylase inhibitors in breast cancer cells". Clinical Chemistry and Laboratory Medicine 43 2 (2005): 151-156. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000227437900006&KeyUID=WOS:000227437900006.
    10.1515/cclm.2005.025
  124. Llorente, E.; Brito, M.L.; Machado, P.; González, M.C.. "Effect of prenatal stress on the hormonal response to acute and chronic stress and on immune parameters in the offspring". Journal of Physiology and Biochemistry 58 3 (2002): 143-150. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036770754&partnerID=MN8TOARS.
  125. Geada, H.; Ribeiro, T.; Brito, R. M.; Espinheira, R.; Rolf, B.; Hohoff, C.; Brinkmann, B.; et al. "A STR mutation in a heteropaternal twin case". Forensic Science International 123 2-3 (2001): 239-242. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000172887100025&KeyUID=WOS:000172887100025.
    10.1016/s0379-0738(01)00494-7
  126. Geada, H.; Brito, R. M.; Ribeiro, T.; Espinheira, R.; Geada, H; Brito, R M; Ribeiro, T; Espinheira, R. "Portuguese population and paternity investigation studies with a multiplex PCR - the AmpFlSTR (R) Profiler Plus (TM)". Forensic Science International 108 1 (2000): 31-37. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000085144600002&KeyUID=WOS:000085144600002.
    10.1016/s0379-0738(99)00091-2
  127. Brito, R. M.; Ribeiro, T.; Viriato, L.; Vieira-Silva, C.; Espinheira, R.; Pinto-Ribeiro, I.; Geada, H.; et al. "Sequence variation of new alleles at the short tandem repeat D19S253 locus". Journal of Forensic Sciences 45 4 (2000): 932-934. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000088055600037&KeyUID=WOS:000088055600037.
  128. Brito, R.M.; Coelho, M.M.; Brito, R. M.; Coelho, M. M.. "Genetic structure of the Iberian chub, Leuciscus pyrenaicus, in the Tejo drainage". Hydrobiologia 392 2 (1999): 169-177. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032788193&partnerID=MN8TOARS.
    10.1023/a:1003510909315
  129. Briolay, J; Galtier, N; Brito, R M; Bouvet, Y. "Molecular phylogeny of Cyprinidae inferred from cytochrome b DNA sequences.". Molecular phylogenetics and evolution 9 1 (1998): 100-8. http://www.ncbi.nlm.nih.gov/pubmed/9479699.
    10.1006/mpev.1997.0441
  130. Brito, R. M.; Ribeiro, T.; Espinheira, R.; Geada, H.; Brito, R M; Ribeiro, T; Espinheira, R; Geada, H. "South Portuguese population data on the loci HLA-DQA1, LDLR, GYPA, HBGG, D7S8 and Gc". Journal of Forensic Sciences 43 5 (1998): 1031-1036. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000075572900016&KeyUID=WOS:000075572900016.
  131. Brito, R M; Briolay, J; Galtier, N; Bouvet, Y; Coelho, M M. "Phylogenetic relationships within genus Leuciscus (Pisces, Cyprinidae) in Portuguese fresh waters, based on mitochondrial DNA cytochrome b sequences.". Molecular phylogenetics and evolution 8 3 (1997): 435-42. http://www.ncbi.nlm.nih.gov/pubmed/9417900.
    10.1006/mpev.1997.0429
  132. Brito, R.M.; Coelho, M.M.; Brito, R. M.; Coelho, M. M.. "Lack of association between enzyme heterozygosity and fitness components in two Iberian cyprinids". Biologia 52 5 (1997): 663-668. http://www.scopus.com/inward/record.url?eid=2-s2.0-0005124948&partnerID=MN8TOARS.
  133. Brito, R. M.; Coelho, M. M.; Brito, R.M.; Coelho, M.M.. "Spatial and temporal genetic variation of Chondrostoma polylepis in the Tejo drainage". Folia Zoologica 45 4 (1996): 337-346. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:A1996WC73000006&KeyUID=WOS:A1996WC73000006.
  134. Coelho, M. M.; Brito, R. M.; Pacheco, T. R.; Figueiredo, D.; Pires, A. M.. "Genetic variation and divergence of Leuciscus pyrenaicus and L. carolitertii (Pisces, Cyprinidae)". Journal of Fish Biology 47 sa (1995): 243-258. http://doi.wiley.com/10.1111/j.1095-8649.1995.tb06059.x.
    10.1111/j.1095-8649.1995.tb06059.x
  135. Frade Garcia, R.; Cortabarria, C.; Brito, M.L.; Domenenech, E.. "'Pseudotumor cerebri': For the purpose of an observation after an episode of haemolytic anaemia | PSEUDOTUMOR CEREBRI: A PROPOSITO DE UNA OBSERVACION TRAS EPISODIO DE ANEMIA HEMOLITICA". Acta Pediatrica Espanola 44 1 (1986): 22-25. http://www.scopus.com/inward/record.url?eid=2-s2.0-0022635188&partnerID=MN8TOARS.
Capítulo de livro
  1. Ribeiro, Edna; Oliveira, Ketlyn; Dias, Marta; Gomes, Bianca; Pimenta, Raquel; Delgadinho, Mariana; Ginete, Catarina; et al. "Towards an integrated approach on occupational health to tackle COVID-19 pandemic". Springer, 2024.
    10.1007/978-3-031-38277-2_22
  2. Ladeira, Carina; Gomes, M. C.; Brito, Miguel. "Human nutrition, DNA damage and cancer: a review". 2014.
    10.3920/978-90-8686-787-5_3
  3. Viegas, Susana; Ladeira, Carina; Gomes, Mário; Nunes, Carla; Brito, Miguel; Prista, João. "Genotoxic effects of exposure to formaldehyde in two different occupational settings". InTech, 2012.
  4. Ladeira, Carina; Viegas, Susana; Carolino, Elisabete; Gomes, Manuel Carmo; Brito, Miguel. "Genotoxicity biomarkers: application in histopathology laboratories". InTech, 2012.
  5. Ribeiro, T.; Brito, R. M.; Espinheira, R.; Geada, H.. "Duplex STR analysis of D19S253 and D18S51 in a Portuguese population". editado por Olaisen, B.; Brinkmann, B.; Lincoln, P. J., 285-287. 1998.
  6. Ribeiro, T.; Brito, R. M.; Espinheira, R.; Geada, H.. "New alleles of D12S391 STR locus in a Portuguese population". editado por Olaisen, B.; Brinkmann, B.; Lincoln, P. J., 275-277. 1998.
Livro
  1. Gollmann, G.; Bouvet, Y.; Brito, R. M.; Coelho, M. M.; Collares-Pereira, M. J.; Imsiridou, A.; Karakousis, Y.; Pattee, E.; Triantaphyllidis, C.. Effects of river engineering on genetic structure of European fish populations. 1998.
Pré-impressão
  1. Gonçalves; João Mário Pedro; Carina Silva; Magalhães; Miguel Brito. "Influence of cigarette smoking on the Index of Cardiac Electrophysiological Balance in apparently healthy Angolans". 2023. https://doi.org/10.21203/rs.3.rs-3171497/v1.
    10.21203/rs.3.rs-3171497/v1

Outros

Outra produção
  1. Cardiovascular risk assessment in Angolan adults: a descriptive analysis from CardioBengo, a community-based survey. From a community-based survey conducted in Angola, 468 individuals aged 40 to 64 years and not using drug therapy were evaluated according to the World Health Organisation STEPwise Approach to Chronic Disease Risk Factor Surveillance. Using data from tobacco use, blood pressure, blood glucose, and total cholesterol levels, we estimated the 10-year risk of a fatal or nonfatal major cardiovascular e. 2018. Pedro, João Mário; Brito, Miguel; Barros, Henrique. http://hdl.handle.net/10400.21/8858.
    10.1155/2018/2532345
  2. Gender and socio-demographic distribution of body mass index: the nutrition transition in an adult Angolan community. This cross-sectional survey with 2357 subjects aged 15 to 64 years from a rural-urban community in Bengo Province, Angola, aimed to evaluate the gender differences in the prevalence of body mass index categories and how socio-demographic characteristics influence it. Women presented a significantly higher prevalence of obesity (10.5% versus 2.8%) but the underweight frequency was similar to men (1. 2018. Pedro, João Mário; Brito, Miguel; Barros, Henrique. http://hdl.handle.net/10400.21/8900.
    10.4081/jphia.2018.865
  3. Tobacco consumption and nicotine dependence in Bengo Province, Angola: a community-based survey. There is concern about the potentially increasing use of tobacco in Angola. However, information on the frequency and determinants of this use is not systematized. This study aimed to estimate the prevalence of tobacco consumption and nicotine dependence among smokers in an Angolan population and considering individual socio-demographic and behavioral characteristics. A community-based survey of 2. 2017. Pedro, João de Almeida; Brito, Miguel; Barros, Henrique; Pedro, J.M.; Brito, M.; Barros, H.. http://hdl.handle.net/10400.21/7696.
    10.1371/journal.pone.0188586
  4. Role of macronutrients and micronutrients in DNA damage. 2017. Ladeira, Carina; Carolino, Elisabete; Gomes, Manuel C.; Brito, Miguel; Centro de Investigação em Saúde Pública (CISP/PHRC). http://hdl.handle.net/10362/33931.
    https://doi.org/10.1177/1178638816684666
  5. A farmacogenética e a medicina personalizada. A farmacogenética tem por objetivo a identificação de diferenças genéticas entre indivíduos que possam influenciar a resposta à terapêutica farmacológica, melhorando a sua eficácia e segurança. Associado à farmacogenética surge a “medicina personalizada”, ou seja, em oposição à existência de um fármaco que consiga tratar todos os pacientes, o tratamento individualizado parece o caminho mais promis. 2015. Brito, Miguel. http://hdl.handle.net/10400.21/5690.
    Brito M. A farmacogenética e a medicina personalizada. Saúde & Tecnologia. 2015;(14):5-10.
  6. Genotoxic assessment in different exposure groups working with antineoplastic agents. Antioneoplastic drugs are widely used in treatment of cancer, and several studies suggest acute and long-term effects associated to antineoplastic drug exposures, namely associating workplace exposure with health effects. Cytokinesis blocked micronucleus (CBMN) assay is one promising short-term genotoxicity assays for human risk assessment and their combination is recommended to monitor population. 2015. Ladeira, Carina; Viegas, Susana; Pádua, Mário; Carolino, Elisabete; Gomes, Manuel C.; Brito, Miguel; Ladeira, C.; et al. http://hdl.handle.net/10400.21/4889.
    10.1201/b18042-37
  7. Importância do polimorfismo OGG1 Ser326Cys no estudo dos efeitos para a saúde que resultam da exposição ocupacional a genotóxicos: o caso da exposição a antioneoplásicos. O ensaio cometa é um dos ensaios de avaliação de genotoxicidade mais promissores de avaliação do risco humano, sendo recomendado para a monitorização de populações com exposição crónica a agentes genotóxicos. Os laboratórios são ambientes profissionais em que os trabalhadores podem encontrar-se expostos a agentes químicos. As drogas antineoplásicas são agentes químicos que são considerados carcino. 2015. Ladeira, Carina; Viegas, Susana; Pádua, Mário; Carolino, Elisabete; Gomes, Manuel C.; Brito, Miguel. http://hdl.handle.net/10400.21/6417.
  8. Detection and quantification of genetically modified soy in foodstuffs, commercialized in Portugal, for human consumption. Biotechnology allows plant and animal genetic modification, leading to genetic modified organisms (GMO). The GMO related benefits and risks are still surrounded in controversy, reason why the consumer has the right to decide about its consumption. The aim of this work is to detect and quantify genetically modified soy in foodstuffs. In that sense, 11 samples from two different lots of the same foo. 2015. Faustino, Rita; Sousa, Ana; Loureiro, Marta; Mendes, Lino; Brito, Miguel. https://web.estesl.ipl.pt/ojs/index.php/ST/article/view/214.
  9. The influence of genetic polymorphisms in XRCC3 and ADH5 genes on the frequency of genotoxicity biomarkers in workers exposed to formaldehyde. The International Agency for Research on Cancer classified formaldehyde as carcinogenic to humans because there is “sufficient epidemiological evidence that it causes nasopharyngeal cancer in humans”. Genes involved in DNA repair and maintenance of genome integrity are critically involved in protecting against mutations that lead to cancer and/or inherited genetic disease. Association studies have. 2013. Ladeira, Carina; Viegas, Susana; Carolino, Elisabete; Gomes, Manuel C.; Brito, Miguel; Gomes, Manuel C. http://hdl.handle.net/10400.21/2581.
    10.1002/em.21755
  10. Differential expression of CDC25 phosphatases splice variants in human breast cancer cells. Background: CDC25 phosphatases control cell cycle progression by activating cyclin dependent kinases. The three CDC25 isoforms encoding genes are submitted to alternative splicing events which generate at least two variants for CDC25A and five for both CDC25B and CDC25C. An over-expression of CDC25 was reported in several types of cancer, including breast cancer, and is often associated with a poo. 2011. Albert, Hélène; Santos, Susana; Battaglia, Eric; Brito, Miguel; Monteiro, Carolino; Bagrel, Denyse; Albert, H{\'{e. http://hdl.handle.net/10400.21/3067.
    10.1515/CCLM.2011.635
  11. Genotoxicity biomarkers in occupational exposure to formaldehyde: the case of histopathology laboratories. Formaldehyde, classified by the IARC as carcinogenic in humans and experimental animals, is a chemical agent that is widely used in histopathology laboratories. The exposure to this substance is epidemiologically linked to cancer and to nuclear changes detected by the cytokinesis-block micronucleus test (CBMN). This method is extensively used in molecular epidemiology, since it provides informatio. 2011. Ladeira, Carina; Viegas, Susana; Carolino, Elisabete; Prista, João; Gomes, Manuel C.; Brito, Miguel; Prista, Jo{\~{a; et al. http://hdl.handle.net/10400.21/214.
    10.1016/j.mrgentox.2010.11.015
  12. Fat intake interacts with polymorphisms of Caspase9, FasLigand and PPARgamma apoptotic genes in modulating Crohn’s disease activity. Background & aims: Crohn’s disease (CD) is a multifactorial disease where resistance to apoptosis is one major defect. Also, dietary fat intake has been shown to modulate disease activity. We aimed to explore the interaction between four single nucleotide polymorphisms (SNPs) in apoptotic genes and dietary fat intake in modulating disease activity in CD patients. Methods: Polymerase Chain Reaction. 2010. Ferreira, Paula; Cravo, Marília; Guerreiro, Catarina Sousa; Tavares, Lourdes; Santos, Paula Moura; Brito, Miguel; Brito, Miguel. http://dx.doi.org/10.1016/j.clnu.2010.06.008.
    http://dx.doi.org/10.1016/j.clnu.2010.06.008
  13. Gene expression regulation and lineage evolution: the North and South tale of the hybrid polyploid Squalius alburnoides complex. The evolution of hybrid polyploid vertebrates, their viability and their perpetuation over evolutionary time have always been questions of great interest. However, little is known about the impact of hybridization and polyploidization on the regulatory networks that guarantee the appropriate quantitative and qualitative gene expression programme. The Squalius alburnoides complex of hybrid fish is. 2010. Pala, Irene; Schartl, Manfred; Brito, Miguel; Malta-Vacas, Joana; Coelho, Maria Manuela; {Malta Vacas. http://hdl.handle.net/10400.21/3069.
    10.1098/rspb.2010.1071
  14. Detecção e quantificação de soja geneticamente modificada em géneros alimentícios, comercializados em Portugal, para consumo humano. A biotecnologia permite modificar geneticamente plantas e animais, dando origem a organismos geneticamente modificados (OGM). Os benefícios e potenciais riscos relacionados com os transgénicos são controversos, pelo que o consumidor tem direito a decidir sobre o seu consumo. A soja é a maior representante do mercado global de transgénicos, tornando-se importante a sua monitorização. O objectivo do. 2009. Faustino, Rita; Sousa, Ana; Loureiro, Marta; Mendes, Lino; Brito, Miguel. http://hdl.handle.net/10400.21/137.
  15. 5' and 3' UTR thymidylate synthase polymorphisms modulate the risk of colorectal cancer independently of the intake of methyl group donors. Thymidylate synthase, as a rate-limiting step in DNA synthesis, catalyses the conversion of dUMP into dTMP using 5,10-methylenotetrahydrofolate as the methyl donor. Two polymorphisms have been described in this gene: a repeat polymorphism in the 5' promoter enhancer region (3R versus 2R) and a 6 bp deletion in the 3' unstranslated region. Both of these may affect protein levels. The present case c. 2008. Carmona, Bruno; Guerreiro, Catarina Sousa; Cravo, Marília; Leitão, Carlos Nobre; Brito, Miguel; Carmona, B.; Guerreiro, C.; et al. http://hdl.handle.net/10400.21/3073.
    10.3892/mmr-00000023
Atividades

Orientação

Título / Tema
Papel desempenhado		 Curso (Tipo)
Instituição / Organização
2020/09/01 - 2024/08/31 Gut microbiome analysis in patients with Sickle Cell Disease
Orientador de Mariana Isabel Neves Delgadinho
 Ciências Biomédicas (Doutoramento)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2020 - 2020 Natural compounds with the capacity to reactivate the gene of gamma-globin and induction of fetal hemoglobin - In vitro test
Orientador
 Engenharia Biomédica (Mestrado)
Instituto Politécnico de Lisboa Instituto Superior de Engenharia de Lisboa, Portugal
2018 - 2018 Oxitocina e Saúde Mental em Estudantes do Ensino Superior
Orientador
 Engenharia Biomédica (Mestrado)
Instituto Politécnico de Lisboa Instituto Superior de Engenharia de Lisboa, Portugal
2018 - 2018 Identificação de modoficadores genéticos em crianças com Anemia de Células Falciformes numa área endémica de Malária, Angola
Orientador
 Ciências Biomédicas (Doutoramento)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2010 - 2010 Farmacogenética e Nutrigenómica na Doença de Crohn
Orientador
 Biologia (Doutoramento)
Universidade de Lisboa Faculdade de Ciências, Portugal
2003 - 2003 Expressão do Gene Erf3/gspt1 e Susceptibilidade À Génese Tumoral Biologia (Doutoramento)
Universidade de Lisboa, Portugal
Distinções

Prémio

2023 Diploma de Mérito, Prémio Ciêntifico IPL-CGD- Tecnologias e Engenharias
Instituto Politécnico de Lisboa, Portugal
2018 Recebeu “Reconhecimento Publico de mérito” pela coordenação do Centro de Investigação em Saúde e Tecnologia (H&TRC) em 2018.
Instituto Politécnico de Lisboa, Portugal
2015 Diploma of Merit" from the Polytechnic Institute of Lisbon for the Scientific Visibility of their research output in the Institute's repository in 2015."
Instituto Politécnico de Lisboa, Portugal