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Nuno Gonçalo Azoia Lopes. Concluiu o(a) Doutoramento em Ciências em 2009/07/28 pelo(a) Universidade do Minho. Publicou 63 artigos em revistas especializadas. Possui 1 capítulo(s) de livros. No seu currículo Ciência Vitae os termos mais frequentes na contextualização da produção científica, tecnológica e artístico-cultural são: laccase; polyethylene glycol; polymerization; template; alcohols; enzyme catalysis; molecular dynamics; template synthesis; Science & Technology; Peptide microarray; Hair keratin; Cosmetic peptide; Cysteine; Hydrophobicity; Cyclo-oligosaccharides; cyclosophoraose; palmitoyl chloride; phase-change; nanoemulsions; ultrasound; Ciências Médicas::Biotecnologia Médica; Molecular dynamics; Hair; Keratin; Pulling; Young's Modulus; Drug delivery; Emulsions; Protein; Solid-in-oil dispersions; Transdermal; Human neutrophil elastase (HNE); Split GFP; Chromogenic GFP-like proteins; Ultramarine (UM); Proteases; Molecular dynamics simulations; Coarse-grained; Ascorbyl tetraisopalmitate; Hair follicle; Stratum corneum; Percutaneous absorption; Human skin; Nanomedicine; albumin; nanoparticles; production methods; specific drug delivery; cancer therapy; Delivery; Dispersion; Fullerene C60; Cosmetics; Engenharia e Tecnologia::Biotecnologia Industrial; Diffusion; immunoassay; protease; inhibitory peptide; nanodispersion; proteolysis; High-pressure homogenizer; Microemulsions; Microparticles; Orange IV; Silk fibroin; In vivo confocal Raman spectroscopy; Retinyl acetate; Skin penetration; Surfactant; Nanodispersion; Transdermal perfusion; Hydrophilic macromolecules; Antimicrobial peptides; Cell-penetrating peptides; Liposome disruption; Membrane active peptides; Inhibition kinetic; Bowman-Birk inhibitor; Peptide; Wound exudate; Protein-based nanoemulsions; High pressure homogenization; PEGylated surfactant; Folic acid; Active targeting; Detergency; Enzymes; Cutinase; Fatty acids; Molecular recognition; Nanoparticles; Bionano materials; siRNA nanoparticles; Gene silencing; Amino acids; Hydrophobic/hydrophilic balance; Microspheres; Proteins; Sonochemistry; Dielectric constant; Free energy; Free energy of solvation; Keratin dimer; Hair fiber; Ethnicity; Lipid; Micro-emulsions; Homogenization; Stabilization; Ultrasound; Bleaching; Odour Control; Controlled Release; Fragrance; Lipid Binding; Lipocalin; Água e Solo; Odour control; Controlled release; Lipid binding; Hyaluronic acid; Bovine serum albumin; Transdermal transport; 547.82; Diels-alder; 2H-azirines; .
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Identificação

Identificação pessoal

Nome completo
Nuno Gonçalo Azoia Lopes

Nomes de citação

  • Nuno G. Azoia
  • Nuno Azoia

Identificadores de autor

Ciência ID
F016-BC7E-7BD3
ORCID iD
0000-0002-7820-4690
Researcher Id
J-2631-2013
Scopus Author Id
6507721674

Endereços de correio eletrónico

  • nuno.azoia@aquitex.pt (Profissional)

Telefones

Telemóvel
  • (+351) 938567187 (Profissional)

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2)
Formação
Grau Classificação
2009/07/28
Concluído
 Ciências (Doutoramento)
Especialização em Especialidade: Química
Universidade do Minho, Portugal
"Reacções de Aza-diels-alder Dirigidas À Sintese de Piperidinas Polihidroxiladas e Tetrahidroquinolinas" (TESE/DISSERTAÇÃO)
1993/10/18 - 2002/04/11
Concluído
 Engenharia Química (Licenciatura)
Universidade de Lisboa Instituto Superior Técnico, Portugal
Percurso profissional

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento 		Empregador
2014/03/01 - 2014/09/30 Assistente convidado (Docente Ensino Superior Politécnico) Instituto Politécnico de Viana do Castelo Escola Superior de Tecnologia e Gestão, Portugal
2003/02/01 - 2006/09/30 Assistente convidado (Docente Ensino Superior Politécnico) Instituto Politécnico de Viana do Castelo Escola Superior de Tecnologia e Gestão, Portugal

Outros

Categoria Profissional
Instituição de acolhimento 		Empregador
2022/08/01 - Atual Innovation Manager Aquitex S.A., Portugal
Aquitex S.A., Portugal
2017/09/02 - 2022/07/31 Investigador Doutorado Centitvc Centro de Nanotecnologia e Materiais Técnicos Funcionais e Inteligentes, Portugal
2009/08/01 - 2017/06/30 Investigador Doutorado - Bolseiro Universidade do Minho, Portugal
2007/04/01 - 2009/07/31 Investigador - Bolseiro Universidade do Minho, Portugal
2001/01/15 - 2003/01/14 Investigador - Bolseiro Universidade do Minho, Portugal
Produções

Publicações

Artigo em conferência
  1. Sande, Maria; Caykara, Tugce; Silva, Carla; Rodrigues, L. R.; Azoia, Nuno. "Design of materials to capture and enrich bacterial samples". 2019.
  2. Antunes, Egipto; Cruz, Célia F.; Azóia, Nuno G.; Cavaco-Paulo, Artur. "Hair keratin molecular dynamics studies". 2017.
  3. Antunes, José Egipto Ferreira; Azóia, Nuno G.; Cavaco-Paulo, Artur. "Hair keratin molecular dynamics models". 2016.
  4. Antunes, José Egipto Ferreira; Azóia, Nuno G.; Cavaco-Paulo, Artur. "Molecular dynamics simulations together with experimental studies reveal strong membrane activity of a small peptide". 2016.
  5. Antunes, José Egipto Ferreira; Azóia, Nuno G.; Cavaco-Paulo, Artur. "Hair keratin molecular dynamics studies". 2016.
  6. Antunes, José Egipto Ferreira; Azóia, Nuno G.; Cruz, Célia F.; Paulo, Artur Cavaco. "Keratin molecular dynamics models". 2014.
  7. Azóia, Nuno G.; Paulo, Artur Cavaco. "Study of transdermal permeation of large molecules bycoarse-grained molecular dynamics simulation". 2014.
Artigo em revista
  1. Rossella Bengalli; Luisa Fiandra; Claudia Vineis; Diego Omar Sanchez-Ramirez; Nuno G. Azoia; Alessio Varesano; Paride Mantecca. "Safety Assessment of Polypyrrole Nanoparticles and Spray-Coated Textiles". Nanomaterials (2021): https://doi.org/10.3390/nano11081991.
    10.3390/nano11081991
  2. Catarina Costa; Nuno G. Azoia; Lorena Coelho; Ricardo Freixo; Patrícia Batista; Manuela Pintado. "Proteins Derived from the Dairy Losses and By-Products as Raw Materials for Non-Food Applications". Foods (2021): https://doi.org/10.3390/foods10010135.
    10.3390/foods10010135
  3. Catarina Costa; Nuno Azoia; Carla Silva; Eduardo Marques. "Textile Industry in a Changing World". U.Porto Journal of Engineering (2020): https://doi.org/10.24840/2183-6493_006.002_0008.
    10.24840/2183-6493_006.002_0008
  4. Ana V. Ferreira; Egipto Antunes; Artur Ribeiro; Teresa Matamá; Nuno G. Azoia; Joana Cunha; Artur Cavaco-Paulo; et al. "Design of a chromogenic substrate for elastase based on split GFP system—Proof of concept for colour switch sensors". Biotechnology Reports 22 (2019): e00324-e00324. https://doi.org/10.1016/j.btre.2019.e00324.
    10.1016/j.btre.2019.e00324
  5. Gonçalves, Filipa Daniela Gomes; Castro, T.; Azóia, Nuno G.; Ribeiro, Artur; Silva, Carla Manuela Pereira Marinho da; Cavaco-Paulo, Artur. "Two Engineered OBPs with opposite temperature-dependent affinities towards 1-aminoanthracene". (2018): http://hdl.handle.net/1822/56333.
    10.1038/s41598-018-33085-8
  6. Nogueira, E.; Passos, M.; Azóia, Nuno G.; Antunes, Egipto; Loureiro, Ana; Guimarães, Diana Isabel Pereira; Jennifer Noro; et al. "Internalization of methotrexate conjugates by folate receptor-a". (2018): http://hdl.handle.net/1822/57418.
    10.1021/acs.biochem.8b00607
  7. Noro, J.; Loureiro, A.; Gonçalves, F.; Azoia, N.G.; Jung, S.; Silva, C.; Cavaco-Paulo, A.; et al. "Oil-based cyclo-oligosaccharide nanodevices for drug encapsulation". Colloids and Surfaces B: Biointerfaces 159 (2017): 259-267. http://www.scopus.com/inward/record.url?eid=2-s2.0-85026861214&partnerID=MN8TOARS.
    10.1016/j.colsurfb.2017.07.055
  8. Martins, M.; Azoia, N.G.; Melle-Franco, M.; Ribeiro, A.; Cavaco-Paulo, A.; Sá, M.; Azóia, Nuno G.; et al. "Permeation of skin with (C60) fullerene dispersions". Engineering in Life Sciences 17 7 (2017): 732-738. http://www.scopus.com/inward/record.url?eid=2-s2.0-85013230556&partnerID=MN8TOARS.
    10.1002/elsc.201600244
  9. Su, Jing; Noro, Jennifer Martins; Loureiro, Ana; Martins, Madalena; Azoia, Nuno G.; Fu, Jiajia; Wang, Qiang; et al. "PEGylation greatly enhances laccase polymerase activity". ChemCatChem 9 20 (2017): 3888-3894. http://hdl.handle.net/1822/58184.
    10.1002/cctc.201700849
  10. Cruz, Célia F.; Azoia, Nuno G.; Matamá, Teresa; Cavaco-Paulo, Artur; Cruz, C.F.; Azoia, N.G.; Matamá, T.; Cavaco-Paulo, A.. "Peptideprotein interactions within human hair keratins". International Journal of Biological Macromolecules 101 (2017): 805-814. http://hdl.handle.net/1822/56408.
    10.1016/j.ijbiomac.2017.03.052
  11. Santos, Laurita dos; Téllez S, Claudio A.; Sousa, Mariane P. J.; Azóia, Nuno G.; Cavaco-Paulo, Artur; Martin, Airton A.; Favero, Priscila P.; et al. "In vivo confocal Raman spectroscopy and molecular dynamics analysis of penetration of retinyl acetate into stratum corneum". Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy 174 (2017): 279-285. http://hdl.handle.net/1822/43867.
    10.1016/j.saa.2016.11.042
  12. Martins, M.; Loureiro, A.; Azoia, N.G.; Silva, C.; Cavaco-Paulo, A.; Martins, Madalena A.; Loureiro, Ana; Azóia, Nuno G.; Cavaco-Paulo, Artur. "Protein Formulations for Emulsions and Solid-in-Oil Dispersions". Trends in Biotechnology 34 6 (2016): 496-505. http://www.scopus.com/inward/record.url?eid=2-s2.0-84961233975&partnerID=MN8TOARS.
    10.1016/j.tibtech.2016.03.001
  13. Loureiro, A.; Azoia, N.G.; Gomes, A.C.; Cavaco-Paulo, A.. "Albumin-based nanodevices as drug carriers". Current Pharmaceutical Design 22 10 (2016): 1371-1390. http://www.scopus.com/inward/record.url?eid=2-s2.0-84961753027&partnerID=MN8TOARS.
    10.2174/1381612822666160125114900
  14. Antunes, José Egipto Ferreira; Cruz, Célia F.; Azóia, Nuno G.; Cavaco-Paulo, Artur; Antunes, E.; Cruz, C.F.; Azoia, N.G.; Cavaco-Paulo, A.. "Insights on the mechanical behavior of keratin fibrils". International Journal of Biological Macromolecules 89 (2016): 477-483. http://hdl.handle.net/1822/41720.
    10.1016/j.ijbiomac.2016.05.018
  15. Machado, N. C. F.; dos Santos, L.; Carvalho, B. G.; Singh, P.; Soto, C. A. Téllez; Azóia, Nuno G.; Cavaco-Paulo, Artur; et al. "Assessment of penetration of Ascorbyl Tetraisopalmitate into biological membranes by molecular dynamics". Computers in Biology and Medicine 75 (2016): 151-159. http://hdl.handle.net/1822/42053.
    10.1016/j.compbiomed.2016.06.003
  16. Loureiro, Ana Isabel Sá; Azóia, Nuno G.; Gomes, Andreia C.; Cavaco-Paulo, Artur. "Albumin-based nanodevices as drug carriers". (2016): http://hdl.handle.net/1822/43314.
    10.2174/1381612822666160125114900
  17. Loureiro, A.; Nogueira, E.; Azoia, N.G.; Sárria, M.P.; Abreu, A.S.; Shimanovich, U.; Rollett, A.; et al. "Size controlled protein nanoemulsions for active targeting of folate receptor positive cells". Colloids and Surfaces B: Biointerfaces 135 (2015): 90-98. http://www.scopus.com/inward/record.url?eid=2-s2.0-84938412704&partnerID=MN8TOARS.
    10.1016/j.colsurfb.2015.06.073
  18. Nogueira, E.; Mangialavori, I.C.; Loureiro, A.; Azoia, N.G.; Sárria, M.P.; Nogueira, P.; Freitas, J.; et al. "Peptide Anchor for Folate-Targeted Liposomal Delivery". Biomacromolecules 16 9 (2015): 2904-2910. http://www.scopus.com/inward/record.url?eid=2-s2.0-84941584525&partnerID=MN8TOARS.
    10.1021/acs.biomac.5b00823
  19. Antunes, José Egipto Ferreira; Cruz, Célia F.; Azóia, Nuno G.; Cavaco-Paulo, Artur; Antunes, E.; Cruz, C.F.; Azoia, N.G.; Cavaco-Paulo, A.. "The effects of solvent composition on the affinity of a peptide towards hair keratin: experimental and molecular dynamics data". RSC Advances 5 16 (2015): 12365-12371. http://hdl.handle.net/1822/38721.
    10.1039/C4RA13901A
  20. Sá, M.; Azóia, Nuno G.; Carvalho, Ana C.; Silva, C.; Matamá, Maria Teresa; Gomes, Andreia C.; Cavaco-Paulo, Artur; et al. "Assessment of a protease inhibitor peptide for anti-ageing". Protein and Peptide Letters 22 11 (2015): 1041-1049. http://hdl.handle.net/1822/38726.
    10.2174/0929866522666150907111351
  21. Ferreira, A. V.; Volkov, Vadim; Abreu, Ana S.; Azóia, Nuno G.; Botelho, C. M.; Paulo, Artur Cavaco; Ferreira, A.V.; et al. "Orange IV stabilizes silk fibroin microemulsions". Engineering in Life Sciences 15 4 (2015): 400-409. http://hdl.handle.net/1822/35205.
    10.1002/elsc.201400190
  22. Martins, Madalena A.; Azóia, Nuno G.; Silva, Carla Manuela Pereira Marinho da; Paulo, Artur Cavaco; Martins, M.; Azoia, N.; Silva, C.; Cavaco-Paulo, A.. "Stabilization of enzymes in micro-emulsions for ultrasound processes". Biochemical Engineering Journal 93 (2015): 115-118. http://hdl.handle.net/1822/31623.
    10.1016/j.bej.2014.09.011
  23. Nogueira, E.; Mangialavori, Irene C.; Loureiro, Ana; Azóia, Nuno G.; Sarria, Marisa P.; Nogueira, Patrícia; Freitas, Jaime; et al. "Peptide anchor for folate-targeted liposomal delivery". (2015): http://hdl.handle.net/1822/37622.
    10.1021/acs.biomac.5b00823
  24. Shimanovich, U.; Munder, A.; Azoia, N.G.; Cavaco-Paulo, A.; Gruzman, A.; Knowles, T.P.J.; Gedanken, A.; et al. "Sonochemically-induced spectral shift as a probe of green fluorescent protein release from nano capsules". RSC Advances 4 20 (2014): 10303-10309. http://www.scopus.com/inward/record.url?eid=2-s2.0-84894264351&partnerID=MN8TOARS.
    10.1039/c3ra47915c
  25. Martins, M.; Azoia, N.G.; Shimanovich, U.; Matamá, T.; Gomes, A.C.; Silva, C.; Cavaco-Paulo, A.; et al. "Design of novel BSA/hyaluronic acid nanodispersions for transdermal pharma purposes". Molecular Pharmaceutics 11 5 (2014): 1479-1488. http://www.scopus.com/inward/record.url?eid=2-s2.0-84899848112&partnerID=MN8TOARS.
    10.1021/mp400657g
  26. Shimanovich, Ulyana; Munder, A.; Loureiro, Ana; Azóia, Nuno G.; Gomes, Andreia; Paulo, Artur Cavaco; Gedanken, Aharon; et al. "Gene silencing by siRNA nanoparticles synthesized via sonochemical method". Journal of Nanomedicine and Nanotechnology 5 3 (2014): http://hdl.handle.net/1822/31685.
    10.4172/2157-7439.1000204
  27. Antunes, E.; Azoia, N.G.; Matamá, T.; Gomes, A.C.; Cavaco-Paulo, A.; Antunes, José Egipto Ferreira; Azóia, Nuno G.; et al. "The activity of LE10 peptide on biological membranes using molecular dynamics, in vitro and in vivo studies". Colloids and Surfaces B: Biointerfaces 106 (2013): 240-247. http://www.scopus.com/inward/record.url?eid=2-s2.0-84874545523&partnerID=MN8TOARS.
    10.1016/j.colsurfb.2013.01.050
  28. Martins, M.; Azoia, N.G.; Ribeiro, A.; Shimanovich, U.; Silva, C.; Cavaco-Paulo, A.; Martins, Margarida Isabel Barros Coelho; et al. "In vitro and computational studies of transdermal perfusion of nanoformulations containing a large molecular weight protein". Colloids and Surfaces B: Biointerfaces 108 (2013): 271-278. http://www.scopus.com/inward/record.url?eid=2-s2.0-84876323919&partnerID=MN8TOARS.
    10.1016/j.colsurfb.2013.02.032
  29. Cruz, Célia F.; Fernandes, Margarida M.; Gomes, Andreia; Coderch, L.; Martí, M.; Méndez, Sandra; Gales, Luís; et al. "Keratins and lipids in ethnic hair". International Journal of Cosmetic Science 35 3 (2013): 244-249. http://hdl.handle.net/1822/22666.
    10.1111/ics.12035
  30. Silva, Carla; Matamá, Teresa; Azoia, Nuno G.; Mansilha, Catarina; Cavaco-Paulo, Artur; Casal, Margarida; Silva, Carla Manuela Pereira Marinho da; et al. "Odorant binding proteins: a biotechnological tool for odour control". Applied Microbiology and Biotechnology 98 8 (2013): 3629-3638. http://hdl.handle.net/10400.18/2078.
    doi:10.1007/s00253-013-5243-9
  31. Azoia, N.G.; Fernandes, M.M.; Micaêlo, N.M.; Soares, C.M.; Cavaco-Paulo, A.; Azóia, Nuno G.; Fernandes, Margarida M.; et al. "Molecular modeling of hair keratin/peptide complex: Using MM-PBSA calculations to describe experimental binding results". Proteins: Structure, Function and Bioinformatics 80 5 (2012): 1409-1417. http://www.scopus.com/inward/record.url?eid=2-s2.0-84859442401&partnerID=MN8TOARS.
    10.1002/prot.24037
  32. Silva, C.; Azoia, N.G.; Martins, M.; Matamá, T.; Wu, J.; Cavaco-Paulo, A.; Silva, Carla Manuela Pereira Marinho da; et al. "Molecular recognition of esterase plays a major role on the removal of fatty soils during detergency". Journal of Biotechnology 161 3 (2012): 228-234. http://www.scopus.com/inward/record.url?eid=2-s2.0-84864753068&partnerID=MN8TOARS.
    10.1016/j.jbiotec.2012.06.019
  33. Silva, Raquel; Ferreira, Helena; Azóia, Nuno G.; Shimanovich, Ulyana; Freddi, G.; Gedanken, Aharon; Paulo, Artur Cavaco; et al. "Insights on the mechanism of formation of protein microspheres in a biphasic system". Molecular Pharmaceutics 9 11 (2012): 3079-3088. http://hdl.handle.net/1822/22652.
    10.1021/mp3001827
  34. Vasconcelos, Andreia; Azóia, Nuno G.; Carvalho, A. C.; Gomes, A. C.; Guebitz, G. M.; Paulo, Artur Cavaco; Vasconcelos, A.; et al. "Tailoring elastase inhibition with synthetic peptides". European Journal of Pharmacology 666 1-3 (2011): 53-60. http://hdl.handle.net/1822/15152.
    10.1016/j.ejphar.2011.05.056
  35. Alves, M.J.; Azoia, N.G.; Fortes, A.G.. "Regio- and stereo-selective aza-Diels-Alder reaction of ethyl glyoxylate 4-methoxyphenylimine with 1,3-dienes in the presence of BF3·Et2O. Evidence for a non-concerted mechanism". Tetrahedron 63 3 (2007): 727-734. http://www.scopus.com/inward/record.url?eid=2-s2.0-33845322646&partnerID=MN8TOARS.
    10.1016/j.tet.2006.10.085
  36. Alves, M. José; Fortes, A. Gil; Azóia, Nuno G.; Alves, M.J.; Azoia, N.G.; Fortes, A.G.. "Synthesis of 1,3,8,8a-tetrahydro-3,8-epoxy[1,2-b]isoquinolines and their reactions with oxygen nucleophiles". Heterocycles 65 6 (2005): 1329-1345. http://hdl.handle.net/1822/3414.
    10.3987/COM-05-10365
  37. Álvares, Y.S.P.; Alves, M.J.; Azoia, N.G.; Bickley, J.F.; Gilchrist, T.L.. "Diastereoselective synthesis of aziridines from (1R)-10-(N,N-dialkylsulfamoyl)isobornyl 2H-azirine-3-carboxylates". Journal of the Chemical Society. Perkin Transactions 1 16 (2002): 1911-1919. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035982161&partnerID=MN8TOARS.
  38. Alves, M.J.; Azoia, N.G.; Bickley, J.F.; Fortes, A.G.; Gilchrist, T.L.; Mendonça, R.; Alves, M. José; et al. "Diels-Alder reactions of alkyl 2H-azirine-3-carboxylates with furans". Journal of the Chemical Society. Perkin Transactions 1 22 (2001): 2969-2976. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034746876&partnerID=MN8TOARS.
    10.1039/b106985n
Capítulo de livro
  1. Lopes, Nuno. "Stereochemistry research trends". 2008.
Tese / Dissertação
  1. Azóia, Nuno G.. "Reacções de Aza-Diels-Alder dirigidas à síntese de piperidinas polihidroxiladas e tetrahidroquinolinas". Doutoramento, 2009. http://hdl.handle.net/1822/9603.