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FILIPE JOSÉ MENEZES MERGULHÃO. Completed the PhD in Chemical Engineering in 2002 by Universidade de Lisboa/Instituto Superior Técnico and the degree Chemical Engineering in 1998 (5 year program) by Universidade de Lisboa/Instituto Superior Técnico. Is an Associate Professor in Universidade do Porto/Faculdade de Engenharia and Researcher in Universidade do Porto Laboratorio de Engenharia de Processos Ambiente Biotecnologia e Energia. Published 105 articles in international journals and has 13 book chapters. Supervised 5 PhD thesis and co-supervised 2.. Supervised 6 MSc dissertation(s). Has received 1 awards and/or honors. Participates and/or participated as Principal investigator in 7 project(s) and as a Researcher in 23 project(s). Works in the area(s) of Natural sciences with emphasis on Biological Sciences , Engineering and Technology with emphasis on Industrial Biotechnology, Bioproducts, Biomaterials and Medical Biotechnology with emphasis on Biomaterials. His main research activities are in the area of Biofilms particularly with application in the Industrial (mainly Food industry), Medical (mainly in biomedical devices and implants) and Environmental (mainly marine biofilms) sectors.
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Identificação

Identificação pessoal

Nome completo
Filipe José Menezes Mergulhão

Nomes de citação

  • Mergulhão, Filipe

Identificadores de autor

Ciência ID
E310-ABDE-8A70
ORCID iD
0000-0001-5233-1037
Scopus Author Id
6506782617

Websites

  • lepabe.fe.up.pt/f_mergulhão (Profissional)
  • https://sigarra.up.pt/feup/pt/func_geral.formview?p_codigo=403865 (Académico)

Domínios de atuação

  • Ciências Naturais - Ciências Biológicas - Microbiologia
  • Ciências Médicas e da Saúde - Biotecnologia Médica - Biomateriais
  • Ciências da Engenharia e Tecnologias - Biotecnologia Industrial - Bioprodutos Biomateriais

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Inglês Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1)
Formação
Grau Classificação
2002
Concluído
 Engenharia Química (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
"Design of bacterial vector systems for the secretion of recombinant proteins" (TESE/DISSERTAÇÃO)
 Approved (maximum classification)
1998
Concluído
 Engenharia Química (Licenciatura)
Universidade de Lisboa Instituto Superior Técnico, Portugal
 16/20
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2007 - Atual Investigador (Investigação) Universidade do Porto Laboratorio de Engenharia de Processos Ambiente Biotecnologia e Energia, Portugal

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento 		Empregador
2022/02/03 - Atual Professor Associado (Docente Universitário) Universidade do Porto Faculdade de Engenharia, Portugal
2005 - 2022 Professor Auxiliar (Docente Universitário) Universidade do Porto Faculdade de Engenharia, Portugal
2012/02/15 - 2012/07/30 Professor Auxiliar Convidado (Docente Universitário) Stanford University Department of Microbiology and Immunology, Estados Unidos
2002 - 2003 Professor Auxiliar (Docente Universitário) Universidade Lusófona de Humanidades e Tecnologias, Portugal
1998 - 1999 Assistente (Docente Universitário) Universidade de Lisboa Instituto Superior Técnico, Portugal

Outros

Categoria Profissional
Instituição de acolhimento 		Empregador
2002 - 2005 Post-doctoral fellow Universidade de Lisboa Instituto Superior Técnico, Portugal
2003 - 2003 Post-doctoral fellow Massachusetts Institute of Technology Department of Chemistry, Estados Unidos
2003 - 2003 Post-doctoral fellow University of Cambridge, Reino Unido
1998 - 2002 PhD fellow Universidade de Lisboa Instituto Superior Técnico, Portugal
2000 - 2000 PhD fellow Kungliga Tekniska Högskolan, Suécia
1997 - 1997 Erasmus fellow University of St Andrews School of Biology, Reino Unido
Projetos

Bolsa

Designação Financiadores
2010 - 2013/11 Bioresist - The influence of biofilm phenotype on its resilience and resistance
Provided by PTCRIS: 105085
Investigador
Fundação para a Ciência e a Tecnologia
2010 - 2013/11 SYNBIOBACTHER - Synthetic biology approaches to engineer "therapeutic" bacteria
Provided by PTCRIS: 102863
Investigador
Fundação para a Ciência e a Tecnologia
2010 - 2013/10 Fouling and cleaning of micro channels
Provided by PTCRIS: 105535
Investigador
Fundação para a Ciência e a Tecnologia
2010 - 2013/10 Filmstart - Initial conditions controlling the onset of biofilms
Provided by PTCRIS: 104940
Investigador responsável
Fundação para a Ciência e a Tecnologia
2009 - 2012/09 Bridging Systems and Synthetic Biology for the development of Improved Microbial Cell Factories
Provided by PTCRIS: 84035
Investigador
Fundação para a Ciência e a Tecnologia
2007 - 2010/09 The interaction between recombinant protein secretion and biofilm formation and stability
Provided by PTCRIS: 69092
Investigador responsável
Fundação para a Ciência e a Tecnologia

Projeto

Designação Financiadores
2018 - Atual FIlmprot - The use of Escherichia coli biofilms for the production of recombinant proteins and other added-value compounds
POCI-01-0145-FEDER-029589
Investigador responsável
Universidade do Porto Laboratorio de Engenharia de Processos Ambiente Biotecnologia e Energia, Portugal
2018 - Atual DelNam - Strengthening the Research Area of Delivery of Nucleic acid mimics (NAMS) into bacteria to fight the antibiotic crisis
810685
810685
Investigador
Universidade do Porto Laboratorio de Engenharia de Processos Ambiente Biotecnologia e Energia, Portugal
 N/A
2017 - Atual PRINT-AID - Multidisciplinary european training network for development of personalized anti-infective medical devices combining printing technologies and antimicrobial functionality
722467
Investigador
Universidade do Porto Laboratorio de Engenharia de Processos Ambiente Biotecnologia e Energia, Portugal
2021 - 2024/02/29 NanoCAT - Using modified carbon nanotubes to prevent biofilm formation in urinary catheters and stents
PTDC/CTM-COM/4844/2020
Universidade do Porto Laboratorio de Engenharia de Processos Ambiente Biotecnologia e Energia, Portugal

Universidade do Porto Faculdade de Engenharia, Portugal
Fundação para a Ciência e a Tecnologia
2020 - 2023/12 SurfSafe - Surface modification to increase microbial SAFEty in the food industry
952471
Investigador responsável
Universidade do Porto Laboratorio de Engenharia de Processos Ambiente Biotecnologia e Energia, Portugal
2015 - 2020/06/30 CVMar+i - Inovação industrial através de colaborações específicas entre empresas e centros de investigação no contexto de valorização biotecnológica marinha
0302_CVMAR_I_1_P
Investigador
Universidade do Porto Laboratorio de Engenharia de Processos Ambiente Biotecnologia e Energia, Portugal
2019 - 2019/12/31 Projeto Estratégico do LEPABE - Laboratório de Engenharia de Processos, Ambiente, Biotecnologia e Energia - Coordinator of the Biotechnology group
UID/EQU/00511/2019
UID/EQU/00511/2019
Investigador
Universidade do Porto Laboratorio de Engenharia de Processos Ambiente Biotecnologia e Energia, Portugal
 N/A
2016 - 2019/09/30 LEPABE-2-ECO-INNOVATION - Coordinator of the Biotechnology group
NORTE-01-0145-FEDER-000005
Investigador
Universidade do Porto Laboratorio de Engenharia de Processos Ambiente Biotecnologia e Energia, Portugal
2015 - 2019/01/31 Pomacea - Tecnologias económicas para controlo de (bio)fouling em membranas através da otimização de métodos de pré-tratamentos de limpeza
INN-INDIGO/0001/2014
Investigador
2015 - 2018/12/31 Projeto Estratégico - UID/EQU/00511/2013 - Coordinator of the Biotechnology group
UID/EQU/00511/2013 - POCI-01-0145-FEDER-006939
Investigador
Universidade do Porto Laboratorio de Engenharia de Processos Ambiente Biotecnologia e Energia, Portugal
2014 - 2015/12/31 Programa Incentivo/EQB/UI0511/2014 - Coordinator of the Biotechnology group
Incentivo/EQB/UI0511/2014
Investigador
Universidade do Porto Laboratorio de Engenharia de Processos Ambiente Biotecnologia e Energia, Portugal
2013 - 2015/10/31 Novomar - Consolidação do Centro Multipolar de Valorização de Recursos Marinhos visando novos usos do mar
0687_NOVOMAR_1_P
Investigador
Universidade do Porto Laboratorio de Engenharia de Processos Ambiente Biotecnologia e Energia, Portugal
2013 - 2015/08 Phytodisinfectants - Disinfection of planktonic bacteria and biofilms in hospital settings with phytochemical products
Provided by PTCRIS: 125925
Investigador
Fundação para a Ciência e a Tecnologia
2014 - 2015/06/30 (Bio) Chemical Engineering: Multi-Scale Approaches for Sustainable Environment and Health - Coordinator of the Biotechnology group
NORTE-07-0124-FEDER-000025
Investigador
Universidade do Porto Laboratorio de Engenharia de Processos Ambiente Biotecnologia e Energia, Portugal
2014 - 2015/06/30 Chemical Engineering: Process Optimization and Energy Conversion - Coordinator of the Biotechnology Group
NORTE-07-0124-FEDER-000026
Investigador
Universidade do Porto Laboratorio de Engenharia de Processos Ambiente Biotecnologia e Energia, Portugal
2013 - 2014/12/31 PROJECTO ESTRATÉGICO - UI 511 - 2013-2014 - Coordinator of the Biotechnology Group
PEst-C/EQB/UI0511/2013
Investigador
Universidade do Porto Laboratorio de Engenharia de Processos Ambiente Biotecnologia e Energia, Portugal
2012 - 2014/12/31 Susclean - Sustainable Cleaning and Disinfection in Fresh-Cut Food Industries
287514
Investigador
Universidade do Porto Laboratorio de Engenharia de Processos Ambiente Biotecnologia e Energia, Portugal
2011 - 2012/12/31 PROJECTO ESTRATÉGICO - UI 511 - 2011-2012
FCOMP-01-0124-FEDER-022677
Investigador
Universidade do Porto Laboratorio de Engenharia de Processos Ambiente Biotecnologia e Energia, Portugal
Produções

Publicações

Artigo em revista
  1. Luciana C. Gomes; Carla Ferreira; Filipe J. Mergulhão. "Implementation of a Practical Teaching Course on Protein Engineering". Biology 11 3 (2022): 387-387. https://doi.org/10.3390/biology11030387.
    10.3390/biology11030387
  2. "Oriented immobilization of Pep19-2.5 on antifouling brushes suppresses the development of Staphylococcus aureus biofilms". Progress in Organic Coatings 163 (2022): 106609-106609. http://dx.doi.org/10.1016/j.porgcoat.2021.106609.
    10.1016/j.porgcoat.2021.106609
  3. Isabel M. Oliveira; Marisa Gomes; Luciana C. Gomes; Manuel F. R. Pereira; Olívia S. G. P. Soares; Filipe J. Mergulhão. "Performance of Graphene/Polydimethylsiloxane Surfaces against S. aureus and P. aeruginosa Single- and Dual-Species Biofilms". Nanomaterials 12 3 (2022): 355-355. https://doi.org/10.3390/nano12030355.
    10.3390/nano12030355
  4. "Using Lactobacilli to Fight Escherichia coli and Staphylococcus aureus Biofilms on Urinary Tract Devices". Antibiotics 10 12 (2021): 1525-1525. http://dx.doi.org/10.3390/antibiotics10121525.
    10.3390/antibiotics10121525
  5. "Antimicrobial coatings based on chitosan to prevent implant-associated infections: A systematic review". iScience 24 12 (2021): 103480-103480. http://dx.doi.org/10.1016/j.isci.2021.103480.
    10.1016/j.isci.2021.103480
  6. "Future Directions for Ureteral Stent Technology: From Bench to the Market". Advanced Therapeutics (2021): 2100158-2100158. http://dx.doi.org/10.1002/adtp.202100158.
    10.1002/adtp.202100158
  7. M.J. Romeu; D. Domínguez-Pérez; D. Almeida; J. Morais; M.J. Araújo; H. Osório; A. Campos; V. Vasconcelos; F.J. Mergulhão. "Quantitative proteomic analysis of marine biofilms formed by filamentous cyanobacterium". Environmental Research 201 (2021): 111566-111566. https://doi.org/10.1016/j.envres.2021.111566.
    10.1016/j.envres.2021.111566
  8. Luciana C. Gomes; Filipe J. M. Mergulhão. "A Selection of Platforms to Evaluate Surface Adhesion and Biofilm Formation in Controlled Hydrodynamic Conditions". Microorganisms 9 9 (2021): 1993-1993. https://doi.org/10.3390/microorganisms9091993.
    10.3390/microorganisms9091993
  9. Alexandra Soares; Luciana C. Gomes; Gabriel A. Monteiro; Filipe J. Mergulhão. "The Influence of Nutrient Medium Composition on Escherichia coli Biofilm Development and Heterologous Protein Expression". Applied Sciences (2021): https://doi.org/10.3390/app11188667.
    10.3390/app11188667
  10. Fábio M. Carvalho; Rita Teixeira-Santos; Filipe J. M. Mergulhão; Luciana C. Gomes. "Effect of Lactobacillus plantarum Biofilms on the Adhesion of Escherichia coli to Urinary Tract Devices". Antibiotics 10 8 (2021): 966-966. https://doi.org/10.3390/antibiotics10080966.
    10.3390/antibiotics10080966
  11. Mergulhão, Filipe. "Development of Chitosan-Based Surfaces to Prevent Single- and Dual-Species Biofilms of Staphylococcus aureus and Pseudomonas aeruginosa". Molecules 26 14 (2021): 4378-4378. http://dx.doi.org/10.3390/molecules26144378.
    10.3390/molecules26144378
  12. "Principal Component Analysis to Determine the Surface Properties That Influence the Self-Cleaning Action of Hydrophobic Plant Leaves". Langmuir 37 27 (2021): 8177-8189. http://dx.doi.org/10.1021/acs.langmuir.1c00853.
    10.1021/acs.langmuir.1c00853
  13. Luciana C. Gomes; Sara I. Faria; Jesus Valcarcel; José A. Vázquez; Miguel A. Cerqueira; Lorenzo Pastrana; Ana I. Bourbon; Filipe J. Mergulhão. "The Effect of Molecular Weight on the Antimicrobial Activity of Chitosan from Loligo opalescens for Food Packaging Applications". Marine Drugs 19 7 (2021): 384-384. https://doi.org/10.3390/md19070384.
    10.3390/md19070384
  14. "Celebrating the centenary in polymer science: Drawing inspiration from nature to develop anti-fouling coatings. The development of biomimetic polymer surfaces and their effect on bacterial fouling". Pure and Applied Chemistry 0 0 (2021): http://dx.doi.org/10.1515/pac-2021-0108.
    10.1515/pac-2021-0108
  15. "Assessment of the environmental compatibility and antifouling performance of an innovative biocidal and foul-release multifunctional marine coating". Environmental Research 198 (2021): 111219-111219. http://dx.doi.org/10.1016/j.envres.2021.111219.
    10.1016/j.envres.2021.111219
  16. Ali Abou-Hassan; Alexandre Barros; Noor Buchholz; Dario Carugo; Francesco Clavica; Petra de Graaf; Julia de La Cruz; et al. "Potential strategies to prevent encrustations on urinary stents and catheters – thinking outside the box: a European network of multidisciplinary research to improve urinary stents (ENIUS) initiative". Expert Review of Medical Devices (2021): https://doi.org/10.1080/17434440.2021.1939010.
    10.1080/17434440.2021.1939010
  17. Sara I. Faria; Rita Teixeira-Santos; Maria J. Romeu; João Morais; Ed de Jong; Jelmer Sjollema; Vítor Vasconcelos; Filipe J. Mergulhão. "Unveiling the Antifouling Performance of Different Marine Surfaces and Their Effect on the Development and Structure of Cyanobacterial Biofilms". Microorganisms (2021): https://doi.org/10.3390/microorganisms9051102.
    10.3390/microorganisms9051102
  18. Marisa Gomes; Luciana C. Gomes; Rita Teixeira-Santos; Manuel F. R. Pereira; Olívia S. G. P. Soares; Filipe J. Mergulhão. "Optimizing CNT Loading in Antimicrobial Composites for Urinary Tract Application". Applied Sciences 11 9 (2021): 4038-4038. https://doi.org/10.3390/app11094038.
    10.3390/app11094038
  19. "The association between initial adhesion and cyanobacterial biofilm development". FEMS Microbiology Ecology 97 5 (2021): http://dx.doi.org/10.1093/femsec/fiab052.
    10.1093/femsec/fiab052
  20. Olga Ferreira; Patrícia Rijo; João Gomes; Ricardo Santos; Sílvia Monteiro; Rita Guedes; Maria Luísa Serralheiro; et al. "Antimicrobial Ceramic Filters for Water Bio-Decontamination". Coatings 11 3 (2021): 323-323. https://doi.org/10.3390/coatings11030323.
    10.3390/coatings11030323
  21. Sara I. Faria; Luciana C. Gomes; Rita Teixeira-Santos; João Morais; Vítor Vasconcelos; Filipe J. M. Mergulhão. "Developing New Marine Antifouling Surfaces: Learning from Single-Strain Laboratory Tests". Coatings 11 1 (2021): 90-90. https://doi.org/10.3390/coatings11010090.
    10.3390/coatings11010090
  22. Mergulhão, Filipe. "Targeting biofilms in medical devices using probiotic cells: a systematic review". AIMS Materials Science 8 4 (2021): 501-523. http://dx.doi.org/10.3934/matersci.2021031.
    10.3934/matersci.2021031
  23. "Surface activation of medical grade polyurethane for the covalent immobilization of an anti-adhesive biopolymeric coating". Journal of Materials Chemistry B 9 17 (2021): 3705-3715. http://dx.doi.org/10.1039/d1tb00278c.
    10.1039/d1tb00278c
  24. Mergulhão, Filipe. "Antimicrobial and anti-adhesive properties of carbon nanotube-based surfaces for medical applications: a systematic review.". iScience (2020): https://europepmc.org/articles/PMC7809508.
    10.1016/j.isci.2020.102001
  25. Fábio M. Carvalho; Rita Teixeira-Santos; Filipe J. M. Mergulhão; Luciana C. Gomes. "The Use of Probiotics to Fight Biofilms in Medical Devices: A Systematic Review and Meta-Analysis". Microorganisms (2020): https://doi.org/10.3390/microorganisms9010027.
    10.3390/microorganisms9010027
  26. Mergulhão, Filipe. "Cell adhesion in microchannel multiple constrictions - Evidence of mass transport limitations.". Colloids and surfaces. B, Biointerfaces (2020): https://doi.org/10.1016/j.colsurfb.2020.111490.
    10.1016/j.colsurfb.2020.111490
  27. Andreia S. Azevedo; Gislaine P. Gerola; João Baptista; Carina Almeida; Joana Peres; Filipe J. Mergulhão; Nuno F. Azevedo. "Increased Intraspecies Diversity in Escherichia coli Biofilms Promotes Cellular Growth at the Expense of Matrix Production". Antibiotics (2020): https://doi.org/10.3390/antibiotics9110818.
    10.3390/antibiotics9110818
  28. Mergulhão, Filipe. "Combining chemistry and topography to fight biofilm formation: Fabrication of micropatterned surfaces with a peptide-based coating.". Colloids and surfaces. B, Biointerfaces (2020): https://doi.org/10.1016/j.colsurfb.2020.111365.
    10.1016/j.colsurfb.2020.111365
  29. Sara I. Faria; Rita Teixeira-Santos; Luciana C. Gomes; Elisabete R. Silva; João Morais; Vítor Vasconcelos; Filipe J. M. Mergulhão. "Experimental Assessment of the Performance of Two Marine Coatings to Curb Biofilm Formation of Microfoulers". Coatings (2020): https://doi.org/10.3390/coatings10090893.
    10.3390/coatings10090893
  30. Maria João Leal Romeu; Dany Domínguez-Pérez; Daniela Almeida; João Morais; Alexandre Campos; Vítor Vasconcelos; Filipe J. M. Mergulhão. "Characterization of planktonic and biofilm cells from two filamentous cyanobacteria using a shotgun proteomic approach". Biofouling (2020): https://doi.org/10.1080/08927014.2020.1795141.
    10.1080/08927014.2020.1795141
  31. Márcia R. Vagos; Marisa Gomes; Joana M. R. Moreira; Olívia S. G. P. Soares; Manuel F. R. Pereira; Filipe J. Mergulhão. "Carbon Nanotube/Poly(dimethylsiloxane) Composite Materials to Reduce Bacterial Adhesion". Antibiotics 9 8 (2020): 434-434. https://doi.org/10.3390/antibiotics9080434.
    10.3390/antibiotics9080434
  32. Patrícia Alves; Joana Maria Moreira; João Mário Miranda; Filipe José Mergulhão. "Analysing the Initial Bacterial Adhesion to Evaluate the Performance of Antifouling Surfaces". Antibiotics 9 7 (2020): 421-421. https://doi.org/10.3390/antibiotics9070421.
    10.3390/antibiotics9070421
  33. P Alves; LC Gomes; M Vorobii; C Rodriguez-Emmenegger; FJ Mergulhão. "The potential advantages of using a poly(HPMA) brush in urinary catheters: effects on biofilm cells and architecture". Colloids and Surfaces B: Biointerfaces (2020): https://doi.org/10.1016/j.colsurfb.2020.110976.
    10.1016/j.colsurfb.2020.110976
  34. Patrícia Alves; Luciana Calheiros Gomes; Cesar Rodríguez-Emmenegger; Filipe José Mergulhão. "Efficacy of A Poly(MeOEGMA) Brush on the Prevention of Escherichia coli Biofilm Formation and Susceptibility". Antibiotics 9 5 (2020): 216-216. https://doi.org/10.3390/antibiotics9050216.
    10.3390/antibiotics9050216
  35. Sara I. Faria; Rita Teixeira-Santos; Maria J. Romeu; João Morais; Vitor Vasconcelos; Filipe J. Mergulhão. "The Relative Importance of Shear Forces and Surface Hydrophobicity on Biofilm Formation by Coccoid Cyanobacteria". Polymers 12 3 (2020): 653-653. https://doi.org/10.3390/polym12030653.
    10.3390/polym12030653
  36. Mergulhão, Filipe. "Magnetron co-sputtered TiO2/SiO2/Ag nanocomposite thin coatings inhibiting bacterial adhesion and biofilm formation". Surface and Coatings Technology (2020): http://dx.doi.org/10.1016/j.surfcoat.2019.125322.
    10.1016/j.surfcoat.2019.125322
  37. Luciana Gomes; Gabriel Monteiro; Filipe Mergulhão. "The Impact of IPTG Induction on Plasmid Stability and Heterologous Protein Expression by Escherichia coli Biofilms". International Journal of Molecular Sciences (2020): https://doi.org/10.3390/ijms21020576.
    10.3390/ijms21020576
  38. Maria J. Romeu; Patrícia Alves; João Morais; João M. Miranda; Ed.D. Jong; Jelmer Sjollema; Vítor Ramos; Vitor Vasconcelos; Filipe J. M. Mergulhão. "Biofilm formation behaviour of marine filamentous cyanobacterial strains in controlled hydrodynamic conditions". Environmental Microbiology 21 11 (2019): 4411-4424. https://doi.org/10.1111/1462-2920.14807.
    10.1111/1462-2920.14807
  39. J Ponmozhi; J. M. R. Moreira; Filipe Mergulhão; J. B. L. M. Campos; Joao Miranda. "Fabrication and Hydrodynamic Characterization of a Microfluidic Device for Cell Adhesion Tests in Polymeric Surfaces". Micromachines (2019): https://www.mdpi.com/2072-666X/10/5/303.
    10.3390/mi10050303
  40. Mergulhão, Filipe. "Evaluating Efficacy of Antimicrobial and Antifouling Materials for Urinary Tract Medical Devices: Challenges and Recommendations". Macromolecular Bioscience (2019): http://dx.doi.org/10.1002/mabi.201800384.
    10.1002/mabi.201800384
  41. Márcia R. Vagos; Joana M.R. Moreira; Olivia S.G.P. Soares; Manuel F.R. Pereira; Filipe J. Mergulhão. "Incorporation of carbon nanotubes in polydimethylsiloxane to control Escherichia coli adhesion". Polymer Composites (2019): https://doi.org/10.1002/pc.25125.
    10.1002/pc.25125
  42. Mergulhão, Filipe. "Recombinant protein expression in biofilms". AIMS Microbiology (2019): http://dx.doi.org/10.3934/microbiol.2019.3.232.
    10.3934/microbiol.2019.3.232
  43. Betina Lopez-Mila; Patrícia Alves; Tomáš Riedel; Barbara Dittrich; Filipe Mergulhão; Cesar Rodriguez-Emmenegger. "Effect of shear stress on the reduction of bacterial adhesion to antifouling polymers". Bioinspiration & Biomimetics 13 6 (2018): 065001-065001. https://doi.org/10.1088/1748-3190/aadcc2.
    10.1088/1748-3190/aadcc2
  44. Mergulhão, Filipe. "The effects of fluid composition and shear conditions on bacterial adhesion to an antifouling peptide-coated surface". MRS Communications (2018): http://dx.doi.org/10.1557/mrc.2018.160.
    10.1557/mrc.2018.160
  45. L.C. Gomes; J. Deschamps; R. Briandet; F.J. Mergulhão. "Impact of modified diamond-like carbon coatings on the spatial organization and disinfection of mixed-biofilms composed of Escherichia coli and Pantoea agglomerans industrial isolates". International Journal of Food Microbiology 277 (2018): 74-82. https://doi.org/10.1016/j.ijfoodmicro.2018.04.017.
    10.1016/j.ijfoodmicro.2018.04.017
  46. Mergulhão, Filipe. "Comparing the Recombinant Protein Production Potential of Planktonic and Biofilm Cells". Microorganisms (2018): http://www.mdpi.com/2076-2607/6/2/48.
    10.3390/microorganisms6020048
  47. L.C. Gomes; J.-C. Piard; R. Briandet; F.J. Mergulhão. "Pseudomonas grimontii biofilm protects food contact surfaces from Escherichia coli colonization". LWT - Food Science and Technology (2017): https://doi.org/10.1016%2Fj.lwt.2017.03.005.
    10.1016/j.lwt.2017.03.005
  48. J.M.R. Moreira; L.C. Gomes; K.A. Whitehead; S. Lynch; L.A. Tetlow; F.J. Mergulhão. "Effect of surface conditioning with cellular extracts on Escherichia coli adhesion and initial biofilm formation". Food and Bioproducts Processing 104 (2017): 1-12. https://doi.org/10.1016%2Fj.fbp.2017.03.008.
    10.1016/j.fbp.2017.03.008
  49. Luciana Calheiros Gomes; Filipe José Mergulhão. "SEM Analysis of Surface Impact on Biofilm Antibiotic Treatment". Scanning (2017):
    10.1155/2017/2960194
  50. Araújo, P.A.; Machado, I.; Meireles, A.; Leiknes, T.; Mergulhão, F.; Melo, L.F.; Simões, M.. "Combination of selected enzymes with cetyltrimethylammonium bromide in biofilm inactivation, removal and regrowth". Food Research International 95 (2017): 101-107. http://www.scopus.com/inward/record.url?eid=2-s2.0-85014941229&partnerID=MN8TOARS.
    10.1016/j.foodres.2017.02.016
  51. Gomes, L.C.; Mergulhão, F.J.. "Heterologous protein production in Escherichia coli biofilms: A non-conventional form of high cell density cultivation". Process Biochemistry 57 (2017): 1-8. http://www.scopus.com/inward/record.url?eid=2-s2.0-85017439544&partnerID=MN8TOARS.
    10.1016/j.procbio.2017.03.018
  52. Meireles, A.; Fulgêncio, R.; Machado, I.; Mergulhão, F.; Melo, L.; Simões, M.. "Characterization of the heterotrophic bacteria from a minimally processed vegetables plant". LWT - Food Science and Technology 85 (2017): 293-300. http://www.scopus.com/inward/record.url?eid=2-s2.0-85010878293&partnerID=MN8TOARS.
    10.1016/j.lwt.2017.01.038
  53. Gomes, L.C.; Mergulhão, F.J.. "Effects of antibiotic concentration and nutrient medium composition on Escherichia coli biofilm formation and green fluorescent protein expression". FEMS Microbiology Letters 364 5 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85018334955&partnerID=MN8TOARS.
    10.1093/femsle/fnx042
  54. Azevedo, A.S.; Almeida, C.; Gomes, L.C.; Ferreira, C.; Mergulhão, F.J.; Melo, L.F.; Azevedo, N.F.. "An in vitro model of catheter-associated urinary tract infections to investigate the role of uncommon bacteria on the Escherichia coli microbial consortium". Biochemical Engineering Journal 118 (2017): 64-69. http://www.scopus.com/inward/record.url?eid=2-s2.0-84998772458&partnerID=MN8TOARS.
    10.1016/j.bej.2016.11.013
  55. Costa, A.M.; Mergulhão, F.J.; Briandet, R.; Azevedo, N.F.. "It is all about location: How to pinpoint microorganisms and their functions in multispecies biofilms". Future Microbiology 12 11 (2017): 987-999. http://www.scopus.com/inward/record.url?eid=2-s2.0-85028548191&partnerID=MN8TOARS.
    10.2217/fmb-2017-0053
  56. Azeredo, J.; Azevedo, N.F.; Briandet, R.; Cerca, N.; Coenye, T.; Costa, A.R.; Desvaux, M.; et al. "Critical review on biofilm methods". Critical Reviews in Microbiology 43 3 (2017): 313-351. http://www.scopus.com/inward/record.url?eid=2-s2.0-85014963888&partnerID=MN8TOARS.
    10.1080/1040841x.2016.1208146
  57. Mergulhão, Filipe. "Surface conditioning with Escherichia coli cell wall components can reduce biofilm formation by decreasing initial adhesion". AIMS Microbiology (2017): http://dx.doi.org/10.3934/microbiol.2017.3.613.
    10.3934/microbiol.2017.3.613
  58. L.C. Gomes; D. Carvalho; R. Briandet; F.J. Mergulhão. "Temporal variation of recombinant protein expression in Escherichia coli biofilms analysed at single-cell level". Process Biochemistry 51 9 (2016): 1155-1161. https://doi.org/10.1016%2Fj.procbio.2016.05.016.
    10.1016/j.procbio.2016.05.016
  59. Gomes IB; Malheiro J; Mergulhão F; Maillard JY; Simões M. "Comparison of the efficacy of natural-based and synthetic biocides to disinfect silicone and stainless steel surfaces.". (2016): http://europepmc.org/abstract/med/26926153.
    10.1093/femspd/ftw014
  60. Araújo, P.A.; Malheiro, J.; MacHado, I.; Mergulhão, F.; Melo, L.; Simões, M.; Araujo, PA; et al. "Influence of flow velocity on the characteristics of pseudomonas fluorescens biofilms". Journal of Environmental Engineering (United States) 142 7 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84975247417&partnerID=MN8TOARS.
    10.1061/(ASCE)EE.1943-7870.0001068
  61. Moreira, J.M.R.; Fulgêncio, R.; Alves, P.; Machado, I.; Bialuch, I.; Melo, L.F.; Simões, M.; Mergulhão, F.J.. "Evaluation of SICAN performance for biofouling mitigation in the food industry". Food Control 62 (2016): 201-207. http://www.scopus.com/inward/record.url?eid=2-s2.0-84946595450&partnerID=MN8TOARS.
    10.1016/j.foodcont.2015.10.023
  62. Moreira, J.M.R.; Fulgêncio, R.; Oliveira, F.; Machado, I.; Bialuch, I.; Melo, L.F.; Simões, M.; Mergulhão, F.J.. "Evaluation of SICON® surfaces for biofouling mitigation in critical process areas". Food and Bioproducts Processing 98 (2016): 173-180. http://www.scopus.com/inward/record.url?eid=2-s2.0-84956686618&partnerID=MN8TOARS.
    10.1016/j.fbp.2016.01.009
  63. Gomes, LC; Mergulhao, FJ. "Effect of heterologous protein expression on Escherichia coli biofilm formation and biocide susceptibility". AIMS MICROBIOLOGY (2016):
    10.3934/microbiol.2016.4.434
  64. Machado, I.; Meireles, A.; Fulgêncio, R.; Mergulhão, F.; Simões, M.; Melo, L.F.. "Disinfection with neutral electrolyzed oxidizing water to reduce microbial load and to prevent biofilm regrowth in the processing of fresh-cut vegetables". Food and Bioproducts Processing 98 (2016): 333-340. http://www.scopus.com/inward/record.url?eid=2-s2.0-84961794771&partnerID=MN8TOARS.
    10.1016/j.fbp.2016.02.008
  65. Moreira, J.M.R.; Ponmozhi, J.; Campos, J.B.L.M.; Miranda, J.M.; Mergulhão, F.J.. "Micro- and macro-flow systems to study Escherichia coli adhesion to biomedical materials". Chemical Engineering Science 126 (2015): 440-445. http://dx.doi.org/10.1016/j.ces.2014.12.054.
    Aceite para publicação • 10.1016/j.ces.2014.12.054
  66. Malheiro, J.; Araújo, P.; Machado, I.; Lemos, M.; Mergulhão, F.; Melo, L.; Simões, M.. "The Effects of Selected Brominated and Chlorinated Chemicals on Pseudomonas Fluorescens Planktonic Cells and Flow-Generated Biofilms". Journal of Food Processing and Preservation (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84949257163&partnerID=MN8TOARS.
    10.1111/jfpp.12609
  67. Lemos, M.; Mergulhão, F.; Melo, L.; Simões, M.. "The effect of shear stress on the formation and removal of Bacillus cereus biofilms". Food and Bioproducts Processing 93 (2015): 242-248. http://www.scopus.com/inward/record.url?eid=2-s2.0-84956571746&partnerID=MN8TOARS.
    10.1016/j.fbp.2014.09.005
  68. Lemos, M.; Gomes, I.; Mergulhão, F.; Melo, L.; Simões, M.. "The effects of surface type on the removal of Bacillus cereus and Pseudomonas fluorescens single and dual species biofilms". Food and Bioproducts Processing 93 (2015): 234-241. http://www.scopus.com/inward/record.url?eid=2-s2.0-84956571748&partnerID=MN8TOARS.
    10.1016/j.fbp.2014.08.009
  69. Pogiatzis, T.A.; Vassiliadis, V.S.; Mergulhão, F.J.; Wilson, D.I.. "Choosing when to clean and how to clean biofilms in heat exchangers". Heat Transfer Engineering 36 (2015): 676-684. http://www.scopus.com/inward/record.url?eid=2-s2.0-84910656178&partnerID=MN8TOARS.
    10.1080/01457632.2015.954940
  70. Moreira, J.M.R.; Simões, M.; Melo, L.F.; Mergulhão, F.J.. "The combined effects of shear stress and mass transfer on the balance between biofilm and suspended cell dynamics". Desalination and Water Treatment 53 12 (2015): 3348-3354. http://www.scopus.com/inward/record.url?eid=2-s2.0-84923541231&partnerID=MN8TOARS.
    10.1080/19443994.2014.933625
  71. Gomes, L.C.; Silva, L.N.; Simões, M.; Melo, L.F.; Mergulhão, F.J.. "Escherichia coli adhesion, biofilm development and antibiotic susceptibility on biomedical materials". Journal of Biomedical Materials Research - Part A 103 4 (2015): 1414-1423. http://www.scopus.com/inward/record.url?eid=2-s2.0-84923575956&partnerID=MN8TOARS.
    10.1002/jbm.a.35277
  72. Moreira, J.M.R.; Gomes, L.C.; Simões, M.; Melo, L.F.; Mergulhão, F.J.. "The impact of material properties, nutrient load and shear stress on biofouling in food industries". Food and Bioproducts Processing 95 (2015): 228-236. http://www.scopus.com/inward/record.url?eid=2-s2.0-84934992919&partnerID=MN8TOARS.
    10.1016/j.fbp.2015.05.011
  73. Gomes LC; Moreira JM; Simões M; Melo LF; Mergulhão FJ. "Biofilm localization in the vertical wall of shaking 96-well plates.". (2014): http://europepmc.org/abstract/med/24834360.
    10.1155/2014/231083
  74. Lemos, M.; Borges, A.; Teodósio, J.; Araújo, P.; Mergulhão, F.; Melo, L.; Simões, M.. "The effects of ferulic and salicylic acids on Bacillus cereus and Pseudomonas fluorescens single- and dual-species biofilms". International Biodeterioration and Biodegradation 86 (2014): 42-51. http://www.scopus.com/inward/record.url?eid=2-s2.0-84887023078&partnerID=MN8TOARS.
    10.1016/j.ibiod.2013.06.011
  75. Abreu, A.C.; Borges, A.; Mergulhão, F.; Simoes, M.. "Use of phenyl isothiocyanate for biofilm prevention and control". International Biodeterioration and Biodegradation 86 (2014): 34-41. http://www.scopus.com/inward/record.url?eid=2-s2.0-84887029148&partnerID=MN8TOARS.
    10.1016/j.ibiod.2013.03.024
  76. Meireles, A.; Machado, I.; Fulgêncio, R.; Mergulhão, F.; Melo, L.; Simões, M.. "Efficacy of antimicrobial combinations to reduce the use of sodium hypochlorite in the control of planktonic and sessile Escherichia coli". Biochemical Engineering Journal (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84924912155&partnerID=MN8TOARS.
    10.1016/j.bej.2015.02.035
  77. Gomes, L.C.; Moreira, J.M.R.; Teodósio, J.S.; Araújo, J.D.P.; Miranda, J.M.; Simões, M.; Melo, L.F.; Mergulhão, F.J.. "96-well microtiter plates for biofouling simulation in biomedical settings". Biofouling 30 5 (2014): 535-546. http://www.scopus.com/inward/record.url?eid=2-s2.0-84900026049&partnerID=MN8TOARS.
    10.1080/08927014.2014.890713
  78. Moreira, J.M.R.; Araújo, J.D.P.; Miranda, J.M.; Simões, M.; Melo, L.F.; Mergulhão, F.J.. "The effects of surface properties on escherichia coli adhesion are modulated by shear stress". Colloids and Surfaces B: Biointerfaces 123 (2014): 1-7. http://www.scopus.com/inward/record.url?eid=2-s2.0-84908539622&partnerID=MN8TOARS.
    10.1016/j.colsurfb.2014.08.016
  79. Araújo, P.A.; Mergulhão, F.; Melo, L.; Simões, M.. "The ability of an antimicrobial agent to penetrate a biofilm is not correlated with its killing or removal efficiency". Biofouling 30 6 (2014): 675-683. http://www.scopus.com/inward/record.url?eid=2-s2.0-84902546839&partnerID=MN8TOARS.
    10.1080/08927014.2014.904294
  80. Moreira, J.M.R.; Simões, M.; Melo, L.F.; Mergulhão, F.J.. "Escherichia coli adhesion to surfaces–a thermodynamic assessment". Colloid and Polymer Science 293 1 (2014): 177-185. http://www.scopus.com/inward/record.url?eid=2-s2.0-84925513387&partnerID=MN8TOARS.
    10.1007/s00396-014-3390-x
  81. Araújo PA; Lemos M; Mergulhão F; Melo L; Simões M. "The Influence of Interfering Substances on the Antimicrobial Activity of Selected Quaternary Ammonium Compounds.". (2013): http://europepmc.org/abstract/med/26904590.
    10.1155/2013/237581
  82. Gomes, L.C.; Moreira, J.M.R.; Miranda, J.M.; Simões, M.; Melo, L.F.; Mergulhão, F.J.. "Macroscale versus microscale methods for physiological analysis of biofilms formed in 96-well microtiter plates". Journal of Microbiological Methods 95 3 (2013): 342-349. http://www.scopus.com/inward/record.url?eid=2-s2.0-84886809883&partnerID=MN8TOARS.
    10.1016/j.mimet.2013.10.002
  83. Moreira, J.M.R.; Gomes, L.C.; Araújo, J.D.P.; Miranda, J.M.; Simões, M.; Melo, L.F.; Mergulhão, F.J.. "The effect of glucose concentration and shaking conditions on Escherichia coli biofilm formation in microtiter plates". Chemical Engineering Science 94 (2013): 192-199. http://www.scopus.com/inward/record.url?eid=2-s2.0-84875583286&partnerID=MN8TOARS.
    10.1016/j.ces.2013.02.045
  84. Teodósio, J.S.; Silva, F.C.; Moreira, J.M.R.; Simões, M.; Melo, L.F.; Alves, M.A.; Mergulhão, F.J.. "Flow cells as quasi-ideal systems for biofouling simulation of industrial piping systems". Biofouling 29 8 (2013): 953-966. http://www.scopus.com/inward/record.url?eid=2-s2.0-84883653767&partnerID=MN8TOARS.
    10.1080/08927014.2013.821467
  85. Moreira, J.M.R.; Teodósio, J.S.; Silva, F.C.; Simões, M.; Melo, L.F.; Mergulhão, F.J.. "Influence of flow rate variation on the development of Escherichia coli biofilms". Bioprocess and Biosystems Engineering 36 11 (2013): 1787-1796. http://www.scopus.com/inward/record.url?eid=2-s2.0-84892373974&partnerID=MN8TOARS.
    10.1007/s00449-013-0954-y
  86. Abreu, A.C.; Tavares, R.R.; Borges, A.; Mergulhão, F.; Simões, M.. "Current and emergent strategies for disinfection of hospital environments". Journal of Antimicrobial Chemotherapy 68 12 (2013): 2718-2732. http://www.scopus.com/inward/record.url?eid=2-s2.0-84887514856&partnerID=MN8TOARS.
    10.1093/jac/dkt281
  87. Teodósio, J.S.; Simões, M.; Mergulhão, F.J.. "The influence of nonconjugative Escherichia coli plasmids on biofilm formation and resistance". Journal of Applied Microbiology 113 2 (2012): 373-382. http://www.scopus.com/inward/record.url?eid=2-s2.0-84864005856&partnerID=MN8TOARS.
    10.1111/j.1365-2672.2012.05332.x
  88. Teodósio, J.S.; Simões, M.; Alves, M.A.; Melo, L.F.; Mergulhão, F.J.. "Setup and validation of flow cell systems for biofouling simulation in industrial settings". The Scientific World Journal 2012 (2012): http://www.scopus.com/inward/record.url?eid=2-s2.0-84871938448&partnerID=MN8TOARS.
    10.1100/2012/361496
  89. Teodósio, J.S.; Simões, M.; Melo, L.F.; Mergulhão, F.J.. "Flow cell hydrodynamics and their effects on E. coli biofilm formation under different nutrient conditions and turbulent flow". Biofouling 27 1 (2011): 1-11. http://www.scopus.com/inward/record.url?eid=2-s2.0-78449260750&partnerID=MN8TOARS.
    10.1080/08927014.2010.535206
  90. Carapuça, E.; Azzoni, A.R.; Prazeres, D.M.F.; Monteiro, G.A.; Mergulhão, F.J.M.. "Time-course determination of plasmid content in eukaryotic and prokaryotic cells using Real-Time PCR". Molecular Biotechnology 37 2 (2007): 120-126. http://www.scopus.com/inward/record.url?eid=2-s2.0-34248999538&partnerID=MN8TOARS.
    10.1007/s12033-007-0007-3
  91. Mergulhão, F.J.; Monteiro, G.A.. "Analysis of factors affecting the periplasmic production of recombinant proteins in Escherichia coli". Journal of Microbiology and Biotechnology 17 8 (2007): 1236-1241. http://www.scopus.com/inward/record.url?eid=2-s2.0-34548502969&partnerID=MN8TOARS.
  92. Mergulhão, F.J.M.; Summers, D.K.; Monteiro, G.A.. "Recombinant protein secretion in Escherichia coli". Biotechnology Advances 23 3 (2005): 177-202. http://www.scopus.com/inward/record.url?eid=2-s2.0-14844283810&partnerID=MN8TOARS.
    10.1016/j.biotechadv.2004.11.003
  93. Mergulhão, F.J.M.; Monteiro, G.A.. "Secretion capacity limitations of the Sec pathway in Escherichia coli". Journal of Microbiology and Biotechnology 14 1 (2004): 128-133. http://www.scopus.com/inward/record.url?eid=2-s2.0-1542285366&partnerID=MN8TOARS.
  94. Mergulhão, F.J.M.; Monteiro, G.A.; Cabral, J.M.S.; Taipa, M.A.. "Design of bacterial vector systems for the production of recombinant proteins in Escherichia coli". Journal of Microbiology and Biotechnology 14 1 (2004): 1-14. http://www.scopus.com/inward/record.url?eid=2-s2.0-1542285371&partnerID=MN8TOARS.
  95. Mergulhão, F.J.M.; Taipa, M.A.; Cabral, J.M.S.; Monteiro, G.A.. "Evaluation of bottlenecks in proinsulin secretion by Escherichia coli". Journal of Biotechnology 109 1-2 (2004): 31-43. http://www.scopus.com/inward/record.url?eid=2-s2.0-1842425886&partnerID=MN8TOARS.
    10.1016/j.jbiotec.2003.10.024
  96. Mergulhão, F.J.M.; Monteiro, G.A.; Larsson, G.; Bostrom, M.; Farewell, A.; Nyström, T.; Cabral, J.M.S.; Taipa, M.A.. "Evaluation of inducible promoters on the secretion of a ZZ-proinsulin fusion protein in Escherichia coli". Biotechnology and Applied Biochemistry 38 1 (2003): 87-93. http://www.scopus.com/inward/record.url?eid=2-s2.0-0042591085&partnerID=MN8TOARS.
    10.1042/BA20030043
  97. Mergulhão, F.J.M.; Monteiro, G.A.; Larsson, G.; Sandén, A.M.; Farewell, A.; Nystrom, T.; Cabral, J.M.S.; Taipa, M.A.. "Medium and copy number effects on the secretion of human proinsulin in Escherichia coli using the universal stress promoters uspA and uspB". Applied Microbiology and Biotechnology 61 5-6 (2003): 495-501. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037899027&partnerID=MN8TOARS.
    10.1007/s00253-003-1232-8
  98. Mergulhão, F.J.M.; Monteiro, G.A.; Cabral, J.M.S.; Taipa, M.A.. "A quantitative ELISA for monitoring the secretion of ZZ-fusion proteins using SpA domain as immunodetection reporter system". Applied Biochemistry and Biotechnology - Part B Molecular Biotechnology 19 3 (2001): 239-244. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035168991&partnerID=MN8TOARS.
    10.1385/mb:19:3:239
  99. Mergulhao, F.J.M.; Monteiro, G.A.; Kelly, A.G.; Taipa, M.A.; Joaquim, M.S.C.. "Recombinant human proinsulin: A new approach in gene assembly and protein expression". Journal of Microbiology and Biotechnology 10 5 (2000): 690-693. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033757725&partnerID=MN8TOARS.
  100. Mergulhão, F.J.M.; Kelly, A.G.; Monteiro, G.A.; Taipa, M.A.; Cabral, J.M.S.. "Troubleshooting in gene splicing by overlap extension: A step-wise method". Applied Biochemistry and Biotechnology - Part B Molecular Biotechnology 12 3 (1999): 285-287. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033428016&partnerID=MN8TOARS.
    10.1385/mb:12:3:285
Capítulo de livro
  1. Gomes, LucianaCalheiros; Silva, LauraNunes; Simões, Manuel; de Melo, LuísFerreira; Mergulhão, FilipeJosé. "Exploring the Antibiotic Effects in Bacterial Biofilms by Epifluorescence and Scanning Electron Microscopy". editado por Polychroniadis, E. K.; Oral, Ahmet Yavuz; Ozer, Mehmet, 241-248. Springer International Publishing, 2015.
    10.1007/978-3-319-16919-4_31
Livro
  1. Romeu, M.J.; Alves, P.; Morais, J.; Ramos, V.; Vasconcelos, V.; Mergulhão, F.J.. Biofilm formation by a cyanobacterium strain belonging to a distinct leptolyngbya phylotype: Surface effect. 2016.
  2. Mergulhão, Filipe. Biofilms in Bioengineering. Nova Science Publishers. 2013.
  3. Teodósio, J.S.; Simões, M.; Melo, L.F.; Mergulhão, F.J.. The influence of arecombinant plasmid on the formation of Escherichia coli biofilms. 2011.
  4. Mergulhão, F.J.; Monteiro, G.A.. Periplasmic targeting of recombinant proteins in Escherichia coli. 2007.
    10.1007/978-1-59745-466-7_4
Resumo em conferência
  1. Mergulhao, FJM; Monteiro, GA. "The secretion efficiency of the Escherichia coli Sec pathway is dependent on the growth phase but not on protein size". 2005.

Outros

Outra produção
  1. Recombinant Protein Production and Plasmid Stability in Escherichia coli Biofilms. 2020. Gomes, LC; Monteiro, GA; Mergulhão, FJ.
    10.5194/biofilms9-65
Atividades

Orientação

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2013/07/22 - Atual Evaluation of bacterial adhesion on carbon nanotube-poly (dimethysiloxane) composite materials
Orientador
 Bioengenharia (Mestrado)
Universidade do Porto Faculdade de Engenharia, Portugal
2013/07/08 - Atual Biofouling and cleaning of microchannels
Coorientador
 Engenharia Química e Biológica (Doutoramento)
Universidade do Porto Faculdade de Engenharia, Portugal
2011/10/09 - Atual Biofilm control with antimicrobial agents: the role of the exopolymeric matrix
Coorientador
 Engenharia Química e Biológica (Doutoramento)
Universidade do Porto Faculdade de Engenharia, Portugal
2019 - 2019 Optimizing Recombinant Protein Production in Escherichia coli biofilms
Orientador
 Engenharia Química e Biológica (Doutoramento)
Universidade do Porto Faculdade de Engenharia, Portugal
2019 - 2019 Marine biofilm formed by coccoid cyanobacteria: Development and Control
Orientador
 Engenharia Química e Biológica (Doutoramento)
Universidade do Porto Faculdade de Engenharia, Portugal
2019 - 2019 Effects of Dedicated Yeasts as Starter Culture Candidates on the Microbial Community and Metabolite Profiles of Cocoa Pulp-Bean Mass Fermentation Processes
Orientador
 Bioengenharia (Mestrado)
Universidade do Porto Faculdade de Engenharia, Portugal
2017 - 2017 Estudo Comparativo de Métodos de Doseamento de Proteína em Preparações de Imunoglobulina Humana Intravenosa
Orientador
 Engenharia Química (Mestrado)
Universidade do Porto Faculdade de Engenharia, Portugal
2017 - 2017 Characterization of marine biofilms formed by filamentous cyanobacteria
Orientador
 Engenharia Química e Biológica (Doutoramento)
Universidade do Porto Faculdade de Engenharia, Portugal
2017 - 2017 Evaluation of Escherichia coli biofilms in controlled hydrodynamic conditions using flow cells
Orientador
 Engenharia Química e Biológica (Doutoramento)
Universidade do Porto Faculdade de Engenharia, Portugal
2016 - 2016 Cloning and expression of a new ketoreductase from the marine bacteria Virgibacillus pantothenticus
Orientador
 Bioengenharia (Mestrado)
Universidade do Porto Faculdade de Engenharia, Portugal
2015 - 2015 Avaliação da influência de células humanas e não-humanas no desenvolvimento de linhas celulares estáveis para produção de TribodyTM5
Orientador
 Engenharia Química (Mestrado)
Universidade do Porto Faculdade de Engenharia, Portugal
2015 - 2015 Marine biofilms - how do they start?
Orientador
 Bioengenharia (Mestrado)
Universidade do Porto Faculdade de Engenharia, Portugal
2013 - 2013 The effect of biofilm formation on recombinant protein expression
Orientador
 Engenharia Química e Biológica (Doutoramento)
Universidade do Porto Faculdade de Engenharia, Portugal
2012 - 2012 Analysis of factors controlling the onset of bacterial biofilms
Orientador
 Engenharia Química e Biológica (Doutoramento)
Universidade do Porto Faculdade de Engenharia, Portugal
2011 - 2011 The interaction between recombinant protein production and biofilm formation and stability
Orientador
 Engenharia Química e Biológica (Doutoramento)
Universidade do Porto Faculdade de Engenharia, Portugal
Distinções

Prémio

2011 Fulbright Scholar Program
Fulbright Association, Estados Unidos