PEDRO JORGE SEQUEIRA COSTA DE JESUS CAMPINHO (DF1E-A3EE-D92D)

Curriculum Vitae

PEDRO JORGE SEQUEIRA COSTA DE JESUS CAMPINHO

P. Campinho completed his undergraduate studies in Microbiology and Genetics in 2005 at the Faculty of Sciences, Lisbon University. Subsequently, he pursued a Ph.D. at the Max-Planck Institute for Cell Biology and Genetics (MPI-CBG) in Dresden, earning his degree in Developmental Biology in 2013 at the Institute of Science and Technology Austria. During his Ph.D., Campinho made significant contributions, demonstrating that tension-oriented cell divisions play a role in facilitating epithelial spreading by fluidizing tissues, as detailed in his 2013 publication (Campinho et al. 2013 NCB). For his first postdoctoral position at the Institut de Génétique et Biologie Moléculaire et Cellulaire (Strasbourg University), Campinho developed a noteworthy live-imaging quantitative analysis method called 3DcylindricMap. This method allowed for the tracking of cell positions in cylindrical tissues. His research revealed that endothelial cell extrusions associated with hematopoietic stem cell generation are influenced by blood flow forces and PKD2-dependent mechanosensing, as published in 2018 (Campinho et al., 2018 Philos Trans R Soc Lond B Biol Sci) and 2020 (Campinho et al. 2020 Cell Rep). In 2020, he started as a senior postdoctoral researcher conducting his independent research line in the Vascular Morphogenesis Lab at Instituto de Medicina Molecular. In 2022, he transitioned to a role as a microscopy and imaging specialist at the Champalimaud Foundation in Lisbon, supporting fellow researchers with their microscopy and imaging projects. Throughout his career, Campinho acquired expertise in cell and molecular biology, biophysics (tissue mechanics), live microscopy, and data analysis. He authored eight peer-reviewed publications, including original research papers, a review, and a book chapter. Campinho's research efforts were recognized through several fellowships, including a Ph.D. stipend and several postdoctoral grants. He actively participated in international meetings and events, presenting his work and contributing to the field. His career reflects a commitment to advancing our understanding of developmental biology and tissue mechanics.

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Identificação

Identificação pessoal

Nome completo: PEDRO JORGE SEQUEIRA COSTA DE JESUS CAMPINHO

Nomes de citação

CAMPINHO, PEDRO

Identificadores de autor

Ciência ID: DF1E-A3EE-D92D
ORCID iD: 0000-0002-8526-5416

Endereços de correio eletrónico

pedro.campinho@research.fchampalimaud.org (Profissional)

Domínios de atuação

Ciências Naturais - Ciências Biológicas - Biologia do Desenvolvimento
Ciências Naturais - Ciências Biológicas - Biofísica
Ciências Naturais - Ciências Biológicas - Biologia Celular

Idiomas

Idioma	Conversação	Leitura	Escrita	Compreensão	Peer-review
Português (Idioma materno)
Inglês	Utilizador proficiente (C1)	Utilizador proficiente (C1)	Utilizador proficiente (C1)	Utilizador proficiente (C1)	Utilizador proficiente (C1)
Francês	Utilizador elementar (A1)	Utilizador elementar (A1)	Utilizador elementar (A1)	Utilizador elementar (A1)

Formação

	Grau	Classificação
2006/09 - 2013/10/15 Concluído	Doutoramento (Doctor of Philosophy) Especialização em Developmental and cell biology; tissue mechanics Institute of Science and Technology Austria, Áustria Max-Planck-Institut für molekulare Zellbiologie und Genetik, Alemanha "Mechanics of zebrafish epiboly: Tension-oriented cell divisions limit anisotropic tissue tension in epithelial spreading" (TESE/DISSERTAÇÃO)	NA
2000/09 - 2005/10/11 Concluído	Biologia (Licenciatura) Especialização em Biologia Microbiana e Genética Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal "Inibição da síntese de colagénio fibrilar no embrião de galinha (Gallus gallus) afecta a epitelização da porção lateral da mesoderme pré-somítica." (TESE/DISSERTAÇÃO)	15

Percurso profissional

Ciência

	Categoria Profissional Instituição de acolhimento	Empregador
2020/09/01 - 2022/01/28	Pós-doutorado (Investigação)	Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal

2014/01/20 - 2020/01/31	Pós-doutorado (Investigação)	Institut de Génétique et de Biologie Moléculaire et Cellulaire, França
	Institut de Génétique et de Biologie Moléculaire et Cellulaire, França
2005/12/01 - 2006/09/30	Investigador Auxiliar (carreira) (Investigação)	Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal
	Universidade de Lisboa Faculdade de Ciências, Portugal
2004/09/12 - 2005/10/11	Estagiário de Investigação (Investigação)	Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal
	Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal (...)

Outros

	Categoria Profissional Instituição de acolhimento	Empregador
2022/02/14 - Atual	Microscopy and Imaging specialist - ABBE platform	Fundação Champalimaud, Portugal
	Fundação Champalimaud, Portugal

Projetos

Bolsa

	Designação	Financiadores
2015/03/01 - 2017/02/28	Mechanics of vascular tissue homeostasis and morphogenesis in response to flow forces EMBO ALTF 100-2014 Bolseiro de Pós-Doutoramento Institut de Génétique et de Biologie Moléculaire et Cellulaire, França	European Molecular Biology Organization (EMBO) Concluído
2006/10/01 - 2010/10/15	Epithelial Junction Remodelling In The Epibolizing Zebrafish Enveloping Cell Layer MPI-CBG 2006 selection Bolseiro de Doutoramento Max-Planck-Institut für molekulare Zellbiologie und Genetik, Alemanha	International Max Planck Research Schools (IMPRS) Concluído

Projeto

	Designação	Financiadores
2017/03/01 - 2018/02/28	Dynamique des cellules endotheliales et mécanique tissulaire lors du développement de l'aorte dorsale FLD 2017 Bolseiro de Pós-Doutoramento Institut de Génétique et de Biologie Moléculaire et Cellulaire, França	Foundation Lefoulon-Delalande Concluído
2014/03/01 - 2015/02/28	Deciphering the downstream effects of PKD2 mediated mechanotransduction in endothelial cells during arterial vessel remodeling FRM SPF20140129238 Bolseiro de Pós-Doutoramento Institut de Génétique et de Biologie Moléculaire et Cellulaire, França	Fondation pour la Recherche Médicale Concluído

Produções

Publicações

Artigo em revista	Cátia Silva Janota; Andreia Pinto; Anna Pezzarossa; Pedro Machado; Judite Costa; Pedro Campinho; Cláudio A. Franco; Edgar R. Gomes. "Shielding of actin by the endoplasmic reticulum impacts nuclear positioning". Nature Communications (2022): https://doi.org/10.1038/s41467-022-30388-3. 10.1038/s41467-022-30388-3 Campinho, Pedro; Vilfan, Andrej; Vermot, Julien. "Blood Flow Forces in Shaping the Vascular System: A Focus on Endothelial Cell Behavior". Frontiers in Physiology 11 (2020): http://dx.doi.org/10.3389/fphys.2020.00552. 10.3389/fphys.2020.00552 Campinho, Pedro; Lamperti, Paola; Boselli, Francesco; Vilfan, Andrej; Vermot, Julien. "Blood Flow Limits Endothelial Cell Extrusion in the Zebrafish Dorsal Aorta". Cell Reports 31 2 (2020): 107505. http://dx.doi.org/10.1016/j.celrep.2020.03.069. 10.1016/j.celrep.2020.03.069 Campinho, Pedro; Lamperti, Paola; Boselli, Francesco; Vermot, Julien. "Three-dimensional microscopy and image analysis methodology for mapping and quantification of nuclear positions in tissues with approximate cylindrical geometry". Philosophical Transactions of the Royal Society B: Biological Sciences 373 1759 (2018): 20170332. http://dx.doi.org/10.1098/rstb.2017.0332. 10.1098/rstb.2017.0332 Campinho P; Behrndt M; Ranft J; Risler T; Minc N; Heisenberg CP. "Tension-oriented cell divisions limit anisotropic tissue tension in epithelial spreading during zebrafish epiboly.". Nature cell biology (2013): http://europepmc.org/abstract/med/24212092. 10.1038/ncb2869 Campinho P; Heisenberg CP. "The force and effect of cell proliferation.". The EMBO journal (2013): http://europepmc.org/abstract/med/24097062. 10.1038/emboj.2013.225 Behrndt M; Salbreux G; Campinho P; Hauschild R; Oswald F; Roensch J; Grill SW; Heisenberg CP. "Forces driving epithelial spreading in zebrafish gastrulation.". Science (New York, N.Y.) (2012): http://europepmc.org/abstract/med/23066079. 10.1126/science.1224143
Capítulo de livro	Smutny, Michael; Behrndt, Martin; Campinho, Pedro; Ruprecht, Verena; Heisenberg, Carl-Philipp. "UV Laser Ablation to Measure Cell and Tissue-Generated Forces in the Zebrafish Embryo In Vivo and Ex Vivo". In Methods in Molecular Biology, 219-235. Springer New York, 2014. Publicado • 10.1007/978-1-4939-1164-6_15
Poster em conferência	CAMPINHO, PEDRO. "Endothelial cell dynamics and tissue mechanics during the development of the dorsal aorta". Trabalho apresentado em EMBO meeting for Mechanical Forces in Biology 2017, 2017. CAMPINHO, PEDRO. "gata1 impairs hematopoietic stem cell formation in the absence of blood flow". Trabalho apresentado em 6th International Conference of the French Society of Angiogenesis (2015; Paris), 2015. CAMPINHO, PEDRO. "The role of Oriented Cell Divisions during Epithelial Spreading in Zebrafish". Trabalho apresentado em Shape and Polarity Symposyum, 2009. CAMPINHO, PEDRO. "Epithelial morphogenesis and junction remodelling". Trabalho apresentado em 5th European Zebrafish Genetics & Development Meeting, 2007.
Tese / Dissertação	CAMPINHO, PEDRO. "Mechanics of zebrafish epiboly: Tension-oriented cell divisions limit anisotropic tissue tension in epithelial spreading". Doutoramento, Institute of Science and Technology Austria, 2013. CAMPINHO, PEDRO. "Inhibition of fibrillar collagen synthesis in chick PSM affects epithelialization of lateral PSM". Licenciatura, Fundação da Faculdade de Ciências da Universidade de Lisboa, 2005.

Atividades

Apresentação oral de trabalho

	Título da apresentação	Nome do evento Anfitrião (Local do evento)
2020/12/11	Blood Flow Limits Endothelial Cell Extrusion in the Zebrafish Dorsal Aorta	Special DiA Meeting - Development in Action Portuguese Society for Developmental Biology (Online event, Portugal)
2016/12/09	Endothelial cell dynamics in the developing dorsal aorta	3rd Tri-regional Stem Cell and Developmental Biology Meeting Tri-national DevStemCell network (Strasbourg, França)
2013/10/25	Tension-oriented cell divisions limit anisotropic tissue tension in epithelial spreading during zebrafish epiboly	2nd meeting of the Portuguese and Spanish Societies for Developmental Biology. (Short talk) Portuguese and Spanish Societies for Developmental Biology (LISBOA, Portugal)

Participação em evento

	Descrição da atividade Tipo de evento	Nome do evento Instituição / Organização
2017/02/14 - 2017/02/16	EMBO Laboratory Management Course for postdocs (2017), Heidelberg, Germany Outro	EMBO Laboratory Management Course for postdocs 2017 European Molecular Biology Organization (EMBO), Alemanha
2016/06/06 - 2016/06/08	Workshop: Imagerie de la morphogenese en 4D: sondes, microscopies et Quantification, INSERM, Bordeaux, France Oficina (workshop)	Imagerie de la morphogenese en 4D: sondes, microscopies et Quantification Institut National de la Santé et de la Recherche Médicale U1035, França
2007/08/13 - 2007/08/17	Workshop: Developing multi-cell developmental and biomedical simulations with CompuCell3D Oficina (workshop)	Developing multi-cell developmental and biomedical simulations with CompuCell3D Indiana University Bloomington Biocomplexity Institute, Estados Unidos
2005/09/15 - 2005/09/17	Workshop: Different tissues, same strategies, common molecules in different developmental systems Oficina (workshop)	Workshop: “Different tissues, same strategies, common molecules in different developmental systems” Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2005/02/23 - 2005/02/25	Workshop: Theoretical and practical course on light microscopy techniques and image analysis Oficina (workshop)	Theoretical and practical course on light microscopy techniques and image analysis Instituto Gulbenkian de Ciência, Portugal

Membro de associação

	Nome da associação	Tipo de participação
2006/10/29 - Atual	Portuguese Society for Developmental Biology (SPBD)	Associado

Outro júri / avaliação

	Descrição da atividade	Instituição / Organização
2020/10 - Atual	Reviewer for the Journal Frontiers in Physiology (Vascular Physiology Section)
2016/06 - 2017	Examining panel evaluating students Master thesis reports/ oral presentations for the Cell Physics Master program (Uni. Strasbourg).	Université de Strasbourg, França

Distinções

Prémio

2017	Postdoctoral fellowship - Foundation Lefoulon-Delalande Foundation Lefoulon-Delalande, França
2015	EMBO Long-Term Fellowship (EMBO ALTF 100-2014) European Molecular Biology Organization (EMBO), Alemanha
2014	Postdoctoral fellowship - French Foundation for Medical Research (FRM SPF20140129238) Fondation pour la Recherche Médicale, França
2009	Travel award to present his work at the symposium Shape and Polarity (RIKEN CDB; Kobe, Japan)
2006	PhD Stipend International Max-Plank Research School (MPI-CBG 2006) Max-Planck-Institut für molekulare Zellbiologie und Genetik, Alemanha