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Miriam González Gómez. Atua na(s) área(s) de Ciências Médicas e da Saúde com ênfase em Medicina Básica com ênfase em Anatomia e Morfologia.
Identificação

Identificação pessoal

Nome completo
Miriam González Gómez

Nomes de citação

  • González Gómez, Miriam
  • González-Gómez M

Identificadores de autor

Ciência ID
D119-72E4-FF23
ORCID iD
0000-0001-5457-0912

Endereços de correio eletrónico

  • mirgon@ull.edu.es (Profissional)

Domínios de atuação

  • Ciências Médicas e da Saúde - Medicina Básica - Anatomia e Morfologia

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Inglês Utilizador independente (B2) Utilizador independente (B2) Utilizador independente (B2) Utilizador independente (B2)
Formação
Grau Classificação
2009
Concluído
 2008/2009 (Doktor (PhD))
Universidad de La Laguna, Espanha
"Neurotensin in the female rat pituitary-gonadal axis; involvement of estrogens and the xenoestrogen bisphenol A " (TESE/DISSERTAÇÃO)
 Excellent Cum Laude
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2006/10/01 - 2007/09/30 Investigador (Investigação) Gobierno de Canarias, Espanha
2005/07/01 - 2006/09/01 Investigador (Investigação) Universidad de La Laguna, Espanha
2004/01/01 - 2004/04/01 Investigador (Investigação) Universidad de La Laguna, Espanha
2000/01/01 - 2001/12/31 Investigador (Investigação) Universidad de La Laguna, Espanha

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento 		Empregador
2016/04/01 - Atual Professor Auxiliar (Docente Universitário) Universidad de La Laguna, Espanha
2008/04/02 - 2011/12/01 Assistente (Docente Universitário) Universidad de La Laguna, Espanha

Outros

Categoria Profissional
Instituição de acolhimento 		Empregador
2011/12/02 - 2016/03/01 Assistant Professor Doctor Universidad de La Laguna, Espanha
Projetos

Projeto

Designação Financiadores
2020/01/01 - 2022/09/30 Alzhéimer en femenino. Caracterización de marcadores tempranos de diagnóstico preventivo y pautas nutricionales.
ProID2020010075
Investigador
Universidad de La Laguna Facultad de Ciencias de la Salud, Espanha
 Agencia Canaria de Investigación Innovación y Sociedad de la Información
Em curso
2017/12 - 2020/12 Papel de p73 como posible regulador de reelin en la función cognitiva durante el envejecimiento y la patología tipo Alzheimer. Implicación de microdominios lipid raft. (SAF2017-84454-R)
SAF2017-84454-R
Investigador responsável
Gobierno de España Ministerio de Ciencia e Innovación
2015/01 - 2017/12 CAMBIOS ASOCIADOS AL ENVEJECIMIENTO EN LOS MICRODOMINIOS DE LA MEMBRANA NEURONAL COMO FACTORES SEMINALES EN PROCESOS DE NEURODEGENERACION
SAF2014-52582-R
Investigador
Universidad de La Laguna - Campus Anchieta, Espanha
 Ministerio de Economía y Competitividad
Concluído
2015/09 - 2017/08 DISEÑO DE ANTIHORMONAS COMO PIGMENTOS LASER CON CAPACIDAD QUIMIOTERAPEUTICA Y FOTOSENSIBILIZANTE PARA EL TRATAMIENTO DE CANCERES DE MAMA Y DE PROSTATA
TEC2014-61743-EXP
Investigador
Ministerio de Economía y Competitividad
Produções

Publicações

Artigo em revista
  1. "Ultrastructural Study of Platelet Behavior and Interrelationship in Sprouting and Intussusceptive Angiogenesis during Arterial Intimal Thickening Formation". International Journal of Molecular Sciences 22 23 (2021): 13001-13001. http://dx.doi.org/10.3390/ijms222313001.
    10.3390/ijms222313001
  2. "Disproportion in Pericyte/Endothelial Cell Proliferation and Mechanisms of Intussusceptive Angiogenesis Participate in Bizarre Vessel Formation in Glioblastoma". Cells 10 10 (2021): 2625-2625. http://dx.doi.org/10.3390/cells10102625.
    10.3390/cells10102625
  3. LUCIO DIAZ-FLORES; Ricardo Gutiérrez; Maria Pino García; MIRIAM GONZALEZ GOMEZ; Rosa Nieves Rodriguez Rodriguez; Carmen Nieves Hernández León; Lucio Díaz-Flores; José Luís Carrasco. "Cd34+ Stromal Cells/Telocytes in Normal and Pathological Skin". International Journal of Molecular Sciences (2021): https://www.mdpi.com/1422-0067/22/14/7342.
    10.3390/ijms22147342
  4. "CD34+ Stromal Cells/Telocytes as a Source of Cancer-Associated Fibroblasts (CAFs) in Invasive Lobular Carcinoma of the Breast". International Journal of Molecular Sciences 22 7 (2021): 3686-3686. http://dx.doi.org/10.3390/ijms22073686.
    10.3390/ijms22073686
  5. Díaz-Flores, Lucio; Gutiérrez, Ricardo; González Gómez, Miriam; García, Mª Pino; Carrasco, José Luis; Díaz-Flores, Lucio Junior; Madrid, Juan F. "Myriad pillars formed by intussusceptive angiogenesis as the basis of intravascular papillary endothelial hyperplasia (IPEH). IPEH is intussusceptive angiogenesis made a lesion.". Histology and histopathology (2020): https://doi.org/10.14670/HH-18-292.
    10.14670/hh-18-292
  6. LUCIO DIAZ-FLORES; Ricardo Gutiérrez; Ma Pino García; MIRIAM GONZALEZ GOMEZ; Jose Luís Carrasco; Hugo Alvarez-Argüelles; Lucio Díaz-Flores. "Telocytes/CD34+ Stromal Cells in Pathologically Affected White Adipose Tissue". International Journal of Molecular Sciences (2020): https://www.mdpi.com/1422-0067/21/24/9694.
    10.3390/ijms21249694
  7. Díaz-Flores, Lucio; Gutiérrez, Ricardo; González-Gómez, Miriam; García, M. A. Pino; Carrasco, José Luis; Madrid, Juan F.; Álvarez-Argüelles, Hugo. "Participation of Intussusceptive Angiogenesis in the Morphogenesis of Lobular Capillary Hemangioma". Scientific Reports 10 1 (2020): http://dx.doi.org/10.1038/s41598-020-61921-3.
    10.1038/s41598-020-61921-3
  8. Díaz-Flores, Lucio; Gutiérrez, Ricardo; Pino García, Mª; González-Gómez, Miriam; Carrasco, José Luis. "Intussusceptive lymphangiogenesis in the sinuses of developing human foetal lymph nodes". Annals of Anatomy - Anatomischer Anzeiger 226 (2019): 73-83. http://dx.doi.org/10.1016/j.aanat.2019.06.004.
    10.1016/j.aanat.2019.06.004
  9. Díaz-Flores, Lucio; Gutiérrez, Ricardo; García, Maria D. P.; Carrasco, José L.; Sáez, Francisco J.; González-Gómez, Miriam; Madrid, Juan F.. "Intussusceptive Lymphangiogenesis in Lymphatic Malformations/Lymphangiomas". The Anatomical Record 302 11 (2019): 2003-2013. http://dx.doi.org/10.1002/ar.24204.
    10.1002/ar.24204
  10. Díaz-Flores, Lucio; Gutiérrez, Ricardo; García, Mª Pino; González-Gómez, Miriam; Carrasco, José Luis; Álvarez-Argüelles, Hugo. "Intussusceptive lymphangiogenesis in vascular transformation of lymph node sinuses". Acta Histochemica 121 4 (2019): 392-399. http://dx.doi.org/10.1016/j.acthis.2019.03.001.
    10.1016/j.acthis.2019.03.001
  11. Meyer, Gundela; González-Arnay, Emilio; Moll, Ute; Nemajerova, Alice; Tissir, Fadel; González-Gómez, Miriam. "Cajal-Retzius neurons are required for the development of the human hippocampal fissure". Journal of Anatomy 235 3 (2019): 569-589. http://dx.doi.org/10.1111/joa.12947.
    10.1111/joa.12947
  12. González Gómez, Miriam. "Intussusceptive lymphangiogenesis in vascular transformation of lymph node sinuses.". Acta histochemica (2019): https://doi.org/10.1016/j.acthis.2019.03.001.
    10.1016/j.acthis.2019.03.001
  13. Ernst, Laura; Darschnik, Simon; Roos, Johannes; González-Gómez, Miriam; Beemelmans, Christa; Beemelmans, Christoph; Engelhardt, Maren; Meyer, Gundela; Wahle, Petra. "Fast prenatal development of the NPY neuron system in the neocortex of the European wild boar, Sus scrofa". Brain Structure and Function 223 8 (2018): 3855-3873. http://dx.doi.org/10.1007/s00429-018-1725-y.
    10.1007/s00429-018-1725-y
  14. Meyer, Gundela; González-Gómez, Miriam. "The heterogeneity of human Cajal-Retzius neurons". Seminars in Cell & Developmental Biology 76 (2018): 101-111. http://dx.doi.org/10.1016/j.semcdb.2017.08.059.
    10.1016/j.semcdb.2017.08.059
  15. Díaz-Flores, Lucio; Gutiérrez, Ricardo; García, M.ª Pino; González-Gómez, M.; Sáez, Francisco J.; Carrasco, José Luis; Madrid, Juan F.. "Sinusoidal hemangioma and intravascular papillary endothelial hyperplasia: Interrelated processes that share a histogenetic piecemeal angiogenic mechanism". Acta Histochemica 120 3 (2018): 255-262. http://dx.doi.org/10.1016/j.acthis.2018.02.007.
    10.1016/j.acthis.2018.02.007
  16. Díaz-Flores, Lucio; Gutiérrez, Ricardo; González-Gómez, Miriam; García, Pino; Sáez, Francisco J.; Díaz-Flores Jr., Lucio; Carrasco, José Luis; Madrid, Juan F.. "Segmentation of Dilated Hemorrhoidal Veins in Hemorrhoidal Disease". Cells Tissues Organs 205 2 (2018): 120-128. http://dx.doi.org/10.1159/000489250.
    10.1159/000489250
  17. González-Arnay, Emilio; González-Gómez, Miriam; Meyer, Gundela. "A Radial Glia Fascicle Leads Principal Neurons from the Pallial-Subpallial Boundary into the Developing Human Insula". Frontiers in Neuroanatomy 11 (2017): http://dx.doi.org/10.3389/fnana.2017.00111.
    10.3389/fnana.2017.00111
  18. Bello, A. R.; Puertas-Avendaño, R. A.; González-Gómez, M. J.; González-Gómez, M.; Laborda, J.; Damas, C.; Ruiz-Hidalgo, M.; Diaz, C.. "Delta-like protein 1 in the pituitary-adipose axis in the adult male mouse". Journal of Neuroendocrinology 29 8 (2017): e12507. http://dx.doi.org/10.1111/jne.12507.
    10.1111/jne.12507
  19. Meyer, Gundela; González-Gómez, Miriam. "The Subpial Granular Layer and Transient Versus Persisting Cajal-Retzius Neurons of the Fetal Human Cortex". Cerebral Cortex 28 6 (2017): 2043-2058. http://dx.doi.org/10.1093/cercor/bhx110.
    10.1093/cercor/bhx110
  20. Carrasco-Juan, JL; Alvarez-Arguëlles, H.; Martín Corriente, MC; González Gómez, Miriam; Valladares-Parrilla, F; Gutiérrez García, R; Díaz-Flores, L.. "Ovarian Leydig cells (OLC): A histomorphological and immunohistochemical study.". Histology and histopathology (2017): https://doi.org/10.14670/HH-11-876.
    10.14670/hh-11-876
  21. Diáz-Flores, L.; Gutiérrez, R.; González Gómez, Miriam; Díaz-Flores, Lucio Junior; Rancel, N; Sáez, F.J.; Madrid, J.F.. "Telocyte Behaviour During Inflammation, Repair and Tumour Stroma Formation.". Advances in experimental medicine and biology (2016): https://doi.org/10.1007/978-981-10-1061-3_12.
    10.1007/978-981-10-1061-3_12
  22. Diáz-Flores, L.; Gutiérrez, R.; Alvarez-Arguëlles, H.; González-Gómez, M.; Garciá, M.D.P.. "Ultrastructure and histogenesis of the acral calcified angioleiomyoma". Ultrastructural Pathology 40 1 (2016): 24-32. http://www.scopus.com/inward/record.url?eid=2-s2.0-84954369781&partnerID=MN8TOARS.
    10.3109/01913123.2015.1120839
  23. Díaz-Flores, L.; Gutiérrez, R.; García, M.P.; González, M.; Sáez, F.J.; Aparicio, F.; Madrid, J.F.. "Human resident CD34+ stromal cells/telocytes have progenitor capacity and are a source of aSMA+ cells during repair". Histology and Histopathology 30 5 (2015): 615-627. http://www.scopus.com/inward/record.url?eid=2-s2.0-84929731972&partnerID=MN8TOARS.
    10.14670/HH-30.615
  24. Díaz-Flores, L.; Gutiérrez, R.; Lizartza, K.; Goméz, M.G.; García, M.D.P.; Sáez, F.J.; Madrid, J.F.. "Behavior of In Situ Human Native Adipose Tissue CD34+ Stromal/Progenitor Cells During Different Stages of Repair. Tissue-Resident CD34+ Stromal Cells as a Source of Myofibroblasts". Anatomical Record 298 5 (2015): 917-930. http://www.scopus.com/inward/record.url?eid=2-s2.0-84927914203&partnerID=MN8TOARS.
    10.1002/ar.23086
  25. González-Gómez, M.; Meyer, G.. "Dynamic expression of calretinin in embryonic and early fetal human cortex". Frontiers in Neuroanatomy 8 JUN (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84902003865&partnerID=MN8TOARS.
    10.3389/fnana.2014.00041
  26. Roy, A.; Gonzalez-Gomez, M.; Pierani, A.; Meyer, G.; Tole, S.. "Lhx2 regulates the development of the forebrain hem system". Cerebral Cortex 24 5 (2014): 1361-1372. http://www.scopus.com/inward/record.url?eid=2-s2.0-84892585594&partnerID=MN8TOARS.
    10.1093/cercor/bhs421
  27. Medina-Bolívar, C.; González-Arnay, E.; Talos, F.; González-Gómez, M.; Moll, U.M.; Meyer, G.. "Cortical hypoplasia and ventriculomegaly of p73-deficient mice: Developmental and adult analysis". Journal of Comparative Neurology 522 11 (2014): 2663-2679. http://www.scopus.com/inward/record.url?eid=2-s2.0-84901661347&partnerID=MN8TOARS.
    10.1002/cne.23556
  28. Hernández-Acosta, N.C.; Cabrera-Socorro, A.; Morlans, M.P.; Delgado, F.J.G.; Suárez-Solá, M.L.; Sottocornola, R.; Lu, X.; González-Gómez, M.; Meyer, G.. "Dynamic expression of the p53 family members p63 and p73 in the mouse and human telencephalon during development and in adulthood". Brain Research 1372 (2011): 29-40. http://www.scopus.com/inward/record.url?eid=2-s2.0-79151486661&partnerID=MN8TOARS.
    10.1016/j.brainres.2010.11.041
  29. Ramírez, C.M.; González, M.; Díaz, M.; Alonso, R.; Ferrer, I.; Santpere, G.; Puig, B.; Meyer, G.; Marin, R.. "VDAC and ERa interaction in caveolae from human cortex is altered in Alzheimer's disease". Molecular and Cellular Neuroscience 42 3 (2009): 172-183. http://www.scopus.com/inward/record.url?eid=2-s2.0-69349092641&partnerID=MN8TOARS.
    10.1016/j.mcn.2009.07.001
  30. Suárez-Solá, M.L.; González-Delgado, F.J.; Pueyo-Morlans, M.; Medina-Bolívar, O.C.; Hernández-Acosta, N.C.; González-Gómez, M.; Meyer, G.. "Neurons in the white matter of the adult human neocortex". Frontiers in Neuroanatomy 3 JUN (2009): http://www.scopus.com/inward/record.url?eid=2-s2.0-77956469274&partnerID=MN8TOARS.
    10.3389/neuro.05.007.2009
  31. Marin, R.; Ramírez, C.; Morales, A.; González, M.; Alonso, R.; Díaz, M.. "Modulation of Aß-induced neurotoxicity by estrogen receptor alpha and other associated proteins in lipid rafts". Steroids 73 9-10 (2008): 992-996. http://www.scopus.com/inward/record.url?eid=2-s2.0-44649182975&partnerID=MN8TOARS.
    10.1016/j.steroids.2007.12.007
  32. Reyes, R.; González, M.; Bello, A.R.. "Origin of adenohypophysial lobes and cells from Rathke's pouch in chicken (Gallus gallus) and Japanese quail (Coturniz coturniz japonica). Expression of calcium-binding proteins". Journal of Veterinary Medicine Series C: Anatomia Histologia Embryologia 37 4 (2008): 272-278. http://www.scopus.com/inward/record.url?eid=2-s2.0-47549111716&partnerID=MN8TOARS.
    10.1111/j.1439-0264.2007.00840.x
  33. Reyes, R.; Martínez, S.; González, M.; Tramu, G.; Bello, A.R.. "Origin of adenohypophysial lobes and cells from Rathke's pouch in Swiss albino mice. Proliferation and expression of Pitx 2 and calbindin D28K in corticotropic and somatotropic cell differentiation". Journal of Veterinary Medicine Series C: Anatomia Histologia Embryologia 37 4 (2008): 263-271. http://www.scopus.com/inward/record.url?eid=2-s2.0-47549101842&partnerID=MN8TOARS.
    10.1111/j.1439-0264.2007.00839.x
  34. Reyes, R.; Valladares, F.; Gutiérrez, R.; González, M.; Bello, A.R.. "Immunohistochemical distribution of regulatory peptides in the human fetal adenohypophysis". Journal of Anatomy 212 6 (2008): 817-826. http://www.scopus.com/inward/record.url?eid=2-s2.0-44649124780&partnerID=MN8TOARS.
    10.1111/j.1469-7580.2008.00906.x
  35. González, M.; Reyes, R.; Damas, C.; Alonso, R.; Bello, A.R.. "Oestrogen receptor a and ß in female rat pituitary cells: An immunochemical study". General and Comparative Endocrinology 155 3 (2008): 857-868. http://www.scopus.com/inward/record.url?eid=2-s2.0-38949214781&partnerID=MN8TOARS.
    10.1016/j.ygcen.2007.10.007
  36. González, M.; Cabrera-Socorro, A.; Pérez-García, C.G.; Fraser, J.D.; López, F.J.; Alonso, R.; Meyer, G.. "Distribution patterns of estrogen receptor a and ß in the human cortex and hippocampus during development and adulthood". Journal of Comparative Neurology 503 6 (2007): 790-802. http://www.scopus.com/inward/record.url?eid=2-s2.0-34548063188&partnerID=MN8TOARS.
    10.1002/cne.21419
  37. Morales, A.; Gonzalez, M.; Marin, R.; Diaz, M.; Alonso, R.. "Estrogen inhibition of norepinephrine responsiveness is initiated at the plasma membrane of GnRH-producing GT1-7 cells". Journal of Endocrinology 194 1 (2007): 193-200. http://www.scopus.com/inward/record.url?eid=2-s2.0-34547467689&partnerID=MN8TOARS.
    10.1677/JOE-06-0001
  38. Marin, R.; Ramírez, C.M.; González, M.; González-Muñoz, E.; Zorzano, A.; Camps, M.; Alonso, R.; Díaz, M.. "Voltage-dependent anion channel (VDAC) participates in amyloid beta-induced toxicity and interacts with plasma membrane estrogen receptor a in septal and hippocampal neurons". Molecular Membrane Biology 24 2 (2007): 148-160. http://www.scopus.com/inward/record.url?eid=2-s2.0-34247402973&partnerID=MN8TOARS.
    10.1080/09687860601055559
  39. Cabrera-Socorro, A.; Hernandez-Acosta, N.C.; Gonzalez-Gomez, M.; Meyer, G.. "Comparative aspects of p73 and Reelin expression in Cajal-Retzius cells and the cortical hem in lizard, mouse and human". Brain Research 1132 1 (2007): 59-70. http://www.scopus.com/inward/record.url?eid=2-s2.0-33846220338&partnerID=MN8TOARS.
    10.1016/j.brainres.2006.11.015
  40. Marin, R.; Ramírez, C.M.; González, M.; Alonso, R.; Díaz, M.. "Alternative estrogen receptors homologous to classical receptor a in murine neural tissues". Neuroscience Letters 395 1 (2006): 7-11. http://www.scopus.com/inward/record.url?eid=2-s2.0-31744451702&partnerID=MN8TOARS.
    10.1016/j.neulet.2005.10.047
  41. Bello, A.R.; Reyes, R.; Hernández, G.; Negrín, I.; González, M.; Tramu, G.; Alonso, R.. "Developmental expression of neurotensin in thyrotropes and gonadotropes of male and female rats". Neuroendocrinology 79 2 (2004): 90-99. http://www.scopus.com/inward/record.url?eid=2-s2.0-1542283678&partnerID=MN8TOARS.
    10.1159/000076632
  42. Sánchez-Criado, J. E.; Guelmes, P.; Bellido, C.; Gónzalez, M.; Hernández, G.; Aguilar, R.; Garrido-Gracia, J. C.; Bello, A. R.; Alonso, R.. "Tamoxifen but not other selective estrogen receptor modulators antagonizes estrogen actions on luteinizing hormone secretion while inducing gonadotropin-releasing hormone self-priming in the rat". Neuroendocrinology 76 4 (2002): 203-13.
    65952
  43. Bello, A.R.; Hernández, G.; González, M.; Reyes, R.; Negrín, I.; Marrero, A.; Sánchez-Criado, J.E.; Tramu, G.; Alonso, R.. "Immunoreactive neurotensin in gonadotrophs and thyrotrophs is regulated by sex steroid hormones in the female rat". Journal of Neuroendocrinology 11 10 (1999): 785-794. http://www.scopus.com/inward/record.url?eid=2-s2.0-0345363050&partnerID=MN8TOARS.
    10.1046/j.1365-2826.1999.00393.x
Artigo em revista (magazine)
  1. Díaz-Flores, Lucio; Gutiérrez, Ricardo; Gayoso, S; García, Mª Pino; González Gómez, Miriam; Díaz-Flores, Lucio Junior; Sánchez, R; Carrasco, JL. "Intussusceptive angiogenesis and its counterpart intussusceptive lymphangiogenesis.", Histology and histopathology, 2020, https://doi.org/10.14670/HH-18-222.
    10.14670/hh-18-222
Capítulo de livro
  1. Pereda, D; Puertas-Avendaño, R; Zjalic, M; Heffer, M; González-Marrero, Ibrahim; González Gómez, Miriam; Díaz, M; Marín, R. "EXTRACELLULAR PROPAGATION OF LIPID RAFT MOLECULAR SPECIES INVOLVED IN PARKINSON DISEASE NEURODEGENERATION". In A closer look to neurotoxicity, 53-74. Nova Science Publishers, Inc., 2020.
    Publicado
  2. Puertas-Avendaño, R; González Gómez, Miriam; Marín, R. "The signalosome malfunctions in age-associated neuropathologies". In The Neuroscience of Dementia. Amsterdam, Países Baixos: Elsevier, 2018.
  3. Meyer, G.; González Gómez, Miriam; Pueyo-Morlans, M.; Carrillo-Padillo, F. "Betz Cells". In Enciclopedia of the neurological sciences, editado por Robert Daroff Michael Aminoff, 417-419. Países Baixos: Elsevier, 2014.
    Publicado
  4. Alonso, R.; Marín, F.; González, M.; Guelmes, P.; Bellido, C.; Hernández, G.; Marín, R.; Díaz, M.; Sánchez-Criado, J.E.. "The hypothalamus-pituitary-ovarian axis as a model system for the study of SERM effects: An overview of experimental and clinical studies". In The Neuroscience of Dementia. 2006.
    10.1007/3-540-34742-9_5
  5. Reyes, Ricardo; González Gómez, Miriam; Negrín, Isabel; Martínez, Salvador; R. Bello, Aixa. "Expresión de proteínas ligantes de calcio durante el desarrollo hipofisario: estudio comparado en mamíferos y aves". In Avances en Endocrinología Comparada. Málaga, Espanha: Universidad de Málaga, 2001.
    Publicado
Atividades

Arbitragem científica em revista

Nome da revista (ISSN) Editora
2021/02/02 - 2021/02/17 Development (0950-1991) The Company of Biologists Ltd