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Carla Alexandra São Bento Viegas. Concluiu o(a) Doutoramento em Doutoramento em 2010 pelo(a) Universidade do Algarve Faculdade de Ciências e Tecnologia e Licenciatura em Bioquimica em 1999 pelo(a) Universidade do Algarve Faculdade de Ciências e Tecnologia. Publicou 44 artigos em revistas especializadas. Possui 1 capítulo(s) de livros. Organizou 9 evento(s). Participou em 16 evento(s). Coorientou 4 tese(s) de doutoramento. Orientou 2 dissertação(ões) de mestrado e coorientou 7. Coorientou 7 trabalho(s) de conclusão de curso de licenciatura/bacharelato. Recebeu 13 prémio(s) e/ou homenagens. Participa e/ou participou como Bolseiro de Doutoramento em 1 projeto(s), Bolseiro de Investigação em 2 projeto(s), Bolseiro de Pós-Doutoramento em 2 projeto(s), Investigador em 10 projeto(s), Investigador responsável em 3 projeto(s), Orientador em 3 projeto(s) e Outra em 5 projeto(s). Atua na(s) área(s) de Ciências Naturais com ênfase em Ciências Biológicas com ênfase em Bioquímica. Nas suas atividades profissionais interagiu com 270 colaborador(es) em coautorias de trabalhos científicos. No seu currículo Ciência Vitae os termos mais frequentes na contextualização da produção científica, tecnológica e artístico-cultural são: Vascular calcification; Calcification inhibitors; Vitamin K-dependent proteins (VKDPs); Inflammation; Cardiovascular disease; Biomarkers; Extracellular vesicles (EVs); Exosomes; .
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Identificação

Identificação pessoal

Nome completo
Carla Alexandra São Bento Viegas

Nomes de citação

  • Viegas, Carla

Identificadores de autor

Ciência ID
C414-F596-EEC6
ORCID iD
0000-0002-5765-3665

Endereços de correio eletrónico

  • caviegas@ualg.pt (Profissional)

Moradas

  • Centro de Ciencias do Mar do Algarve- CCMAR/ Universidade do Algarve. Campus de Gambelas, FCMA, CCMAR, 8005-139, Faro, Faro, Portugal (Profissional)

Domínios de atuação

  • Ciências Naturais - Ciências Biológicas - Bioquímica

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Francês Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1)
Espanhol; Castelhano Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1)
Formação
Grau Classificação
2010/07/16
Concluído
 Biochemistry (Doutoramento)
Especialização em Molecular and Cellular Biology
Universidade do Algarve - Campus de Gambelas, Portugal
"Identification and Characterization of a New Calcium Binding Protein from Sturgeon, Gla Rich Protein or Grp. Contribution to Unveil Its Function in Vertebrates" (TESE/DISSERTAÇÃO)
 Aprovado com Muito Bom
1999
Concluído
 Bioquimica (Licenciatura)
Universidade do Algarve Faculdade de Ciências e Tecnologia, Portugal
"Clonagem do ADNc completo e gene da BGP (“Bone Gla Protein”) em Xenopus laevis" (TESE/DISSERTAÇÃO)
 14 valores
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2025/01/01 - Atual Investigador Auxiliar (carreira) (Investigação) Centro de Ciências do Mar, Portugal
Centro de Ciências do Mar, Portugal
2018/10/24 - 2024/10/23 Investigador Auxiliar (carreira) (Investigação) Universidade do Algarve, Portugal
2014/10/01 - 2017/09/30 Pós-doutorado (Investigação) Centro de Ciências do Mar, Portugal
2011/10/01 - 2014/09/30 Pós-doutorado (Investigação) Centro de Ciências do Mar, Portugal
2011/01/14 - 2011/09/30 Pós-doutorado (Investigação) Centro de Ciências do Mar, Portugal

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento 		Empregador
2017/09/01 - 2018/02/28 Professor Auxiliar Convidado (Docente Universitário) Universidade do Algarve Faculdade de Ciências e Tecnologia, Portugal

Outros

Categoria Profissional
Instituição de acolhimento 		Empregador
2010/04/01 - 2022/12/01 Chief Operating Officer (COO) GenoGla Diagnostics, Portugal
2009/11/01 - 2010/04/01 Research technician Centro de Ciências do Mar, Portugal
2005/04/01 - 2009/09/01 PhD student Universidade do Algarve, Portugal
2007/03/01 - 2007/04/01 Visiting PhD University of California San Diego¿, Estados Unidos
2003/04/01 - 2005/03/01 Superior Research Technician Centro de Ciências do Mar, Portugal
2001/07/01 - 2003/03/01 Research Technician Centro de Ciências do Mar, Portugal
2000/07/01 - 2001/06/01 Research Technician Centro de Ciências do Mar, Portugal
1999/12/01 - 2000/05/01 Research Technician Centro de Ciências do Mar, Portugal
Projetos

Bolsa

Designação Financiadores
2021/03 - 2025/03 ALGAE4IBD –FROM NATURE TO BEDSIDE- ALGAE BASED BIO COMPOUND FOR PREVENTION AND TREATMENT OF INFLAMMATION, PAIN AND IBD (Algae4IBD)
101000501 - Algae4IBD
Investigador
Centro de Ciências do Mar, Portugal
 H2020 Food Security Sustainable Agriculture and Forestry Marine Maritime and Inland Water Research and the Bioeconomy
Em curso
2014/10/01 - 2017/09/30 Unveiling molecular mechanisms of GRP as calcification inhibitor associated with chronic kidney disease (CKD) vascular calcification
SFRH/BPD/70277/2010
Bolseiro de Pós-Doutoramento
Centro de Ciências do Mar, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2011/10/01 - 2014/09/30 Studies for the establishment of GRP as a biomarker for ectopic calcifications. Insights into the role of GRP in tumoral processes.
SFRH/BPD/70277/2010
Bolseiro de Pós-Doutoramento
Centro de Ciências do Mar, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2005/04/01 - 2009/09/30 Identification and characterization of a new calcium binding protein from sturgeon, Gla rich protein or GRP. Contribution to unveil its function in vertebrates.
SFRH/BD/9077/2002
Bolseiro de Doutoramento
Centro de Ciências do Mar, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído

Projeto

Designação Financiadores
2021/03 - 2024/04 Exploring a novel and sustainable sea-based diet supplement to promote longevity and quality of life in a pandemic era (NutriSafe)
AAC nº 41/ALG/2020 - Project nº 072583
Co-Investigador Responsável (Co-IR)
Universidade do Algarve - Campus de Gambelas, Portugal
2021/12/01 - 2023/11/30 Exploring the therapeutic application of Gla-rich protein (GRP) in inflammation-related diseases using natural bioengineered nanovesicles (FlameGRP)
EXPL/BTM-TEC/0990/2021
Investigador responsável
Centro de Ciências do Mar, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2020/10/01 - 2023/09/30 Bioengineer of semi-synthetic extracellular vesicles (EVs) loaded with active g-carboxylated GRP (cGRP-EVs) for therapeutic applications
PID: 7060
Investigador responsável
Em curso
2020/06/01 - 2023/05/31 Characterization of bioengineered extracellular vesicles (EVs) loaded with Gla rich Protein: a proteomic approach.
EPIC-XS2019 project #7
Investigador responsável
Centro de Ciências do Mar, Portugal
Em curso
2021 - 2023 Application of Gla-rich Protein (GRP) in diagnostic and therapeutic of cardiovascular disease in Chronic Kidney Disease patients.
SPN2018
Investigador
Sociedade Portuguesa de Nefrologia
Em curso
2017/01 - 2020/12/30 ALGARED+ "RED transfronteriza para el desarrollo de productos innovadores con microALGAs"
0055_ALGARED_PLUS_5_E
Investigador
Universidade do Algarve, Portugal

Universidad de Huelva, Espanha
Em curso
2018 - 2020 Gla-rich protein (GRP) associated to circulating calciprotein particles (CPP) and extracellular vesicles (EVs) as a novel marker of vascular calcification stress in diabetic with chronic kidney disease (CKD)
SPN-2017
Investigador
Sociedade Portuguesa de Nefrologia
Em curso
2017 - 2020 RED transfronteriza para el desarrollo de productos innovadores con microalgas
ALGARED+, (2017/2020)
Investigador
Em curso
2018 - 2019 Bioexplora: identificación de sustancias bioactivas de microalgas extremófilas obtenidas de zonas mineras de la Eurorregión Alentejo-Algarve-Andalucía
Bioexplora 2018/2019
Investigador
Concluído
2013/05 - 2015/04 New insigths into the mechanism of vascular calcification in chronic kidney disease (CKD): the role of GRP
126102
Provided by PTCRIS: 126102
Investigador responsável
Centro de Ciências do Mar, Portugal
 Fundação para a Ciência e a Tecnologia, I.P.
Concluído
2012/02 - 2015/01 Insights into Gla-rich Protein (GRP) function and molecular mechanism of action in vascular calcification (BioGlaGRP)
Provided by PTCRIS: 117266
117266
Investigador responsável
Centro de Ciências do Mar, Portugal
 Fundação para a Ciência e a Tecnologia, I.P.
2011/01 - 2014/06 A new approach for the identification of osteoarthritis terapeutic targets:The application of 2D-DIGE proteomics
Provided by PTCRIS: 112832
112832
Investigador
Fundação para a Ciência e a Tecnologia, I.P.
2010/01 - 2013/07 Studies for the establishement of GRP as a biomarker for vascular calcification
101186
Provided by PTCRIS: 101186
Investigador
Fundação para a Ciência e a Tecnologia, I.P.
2005/09 - 2008/06 MGP functional role regarding local regulation of extracellular matrix mineralization-Identification of the structural motifs responsible for its function
57921
Provided by PTCRIS: 57921
Outra
Fundação para a Ciência e a Tecnologia, I.P.
2003 - 2006 Desarrollo Esquelético, Alteraciones y Malformaciones durante la Ontogenia Larvaria de Peces de Interés en Acuicultura. Aproximación Molecular, Celular y Bioquímica
MCYT/AGL 2003-03558
Outra
Concluído
2001 - 2004 A costa Portuguesa como limite biogeográfico: Consequências para o sucesso reprodutivo, adaptação local e estrutura genética de populações nos seus limites de distribuição.
PDCTM/P/MAR/2/152999
Outra
Concluído
2000 - 2002 Respostas moleculares ao stress hidrico em algas com elavada tolerância á salinidade e dissecação.
PRAXIS/12203/98
Bolseiro de Investigação
Concluído
1999 - 2001 Function of Bone Gla and Matrix Gla Proteins in fish: Studies on the mineralization of the extracellular matrix from bone, cartilage and soft tissues.
PRAXIS 11159/98
Bolseiro de Investigação
Concluído
1998 - 2001 Molecular Cloning, Tissue distribution and developmental appearance of Matrix Gla protein in the African frog Xenopus laevis.
NATO CRG (SA5-2-05/CRG 940751)
Outra
Concluído
1998 - 2000 Characterization of Matrix Gla and Bone Gla proteins gene expression in different developmental stages of the seabream Sparus aurata.
PRAXIS/ BIA/469/94
Outra
Concluído

Outro

Designação Financiadores
2018 - Atual GreenCoLAB- Laboratório Colaborativo de Tecnologias e Produtos Verdes de Oceano
GreenCoLAB
Investigador
Em curso
2012 - Atual Expression and purification of Gla Rich protein in baculovirus for its use in functional and structural studies
EU/INSTRUCT PID1003201
Investigador
Concluído
2011 - Atual Application of 2DE proteomics to human articular cartilage for identification of new osteoarthritis biomarkers
EU/ PRIME-XS-72
Investigador
Concluído
2018/11/26 - 2018/12/14 Discovery of dermato-protective properties of marine 5-thiohistidines.
EMBRIC Transnational Access Program
Orientador
Concluído
2017/10/02 - 2017/10/14 Discovery of cosmeceutical and pharmaceutical properties of a promising marine natural product.
EMBRIC Transnational Access Program
Orientador
Concluído
2017 - 2017 Sustainable and high-efficient production of Tetraselmis suecica as innovative product with high biological value for cosmeceutical market.
EMBRIC Transnational Access Program
Orientador
Concluído
Produções

Publicações

Artigo em boletim informativo
  1. Viegas, Carla. "Funding: The Portuguese Foundation for Science and Technology", European Perspectives - Circulation, 2012, https://www.ahajournals.org/doi/10.1161/CIR.0b013e31826e3cf4.
  2. Viegas, Carla. "Trabalho liderado por um grupo de investigadores do CCMAR reconhecido pela Kidney International", CCMAR News, 2010, http://www.nature.com/ki/journal/v77/n4/full/ki2009520a.html.
Artigo em conferência
  1. Viegas, Carla; Joana Carreira; Teresa Maia; Francis Impens; Anjos Macedo; António Matos; Dina Simes. Autor correspondente: Viegas, Carla. "Vascular calcification is mediated by different populations of extracellular vesicles (EVs) with specific molecular profiles and differential effects on vascular tissue inflammation". Trabalho apresentado em European Atherosclerosis Society (EAS) 92th Congress, Lyon, 2024.
    Publicado • https://doi.org/10.1016/j.atherosclerosis.2024.117700
  2. Marreiros, Catarina; Viegas, Carla; Guedes, A.M; Silva, A.P.; Àguas, A.C; Faísca, M; Schugers, L; Simes, D.C.. "Gla Rich Protein as a Marker of Cardiovascular Risk in a Peritoneal Dialysis Population". Trabalho apresentado em EuroPD 2023, Bruges, 2023.
  3. Viegas, Carla; Silva, Ana; Macedo, Ana; Mendes, Filipa; Guilherme, Patrícia; Tavares, Nelson; Dias, Carolina; et al. "P0873GLA-RICH PROTEIN (GRP) AS AN EARLY AND NOVEL MARKER ASSOCIATED WITH VASCULAR CALCIFICATION AND CKD-MINERAL AND BONE DISORDER (MBD) IN DIABETIC PATIENTS WITH CKD: A PILOT COHORT STUDY". Trabalho apresentado em 57TH ERA-EDTA, 2020.
    10.1093/ndt/gfaa143.p0873
  4. Viegas, Carla. "Anti-inflammatory activity of microalgae-derived bioactives with potential dermoprotective applications". Trabalho apresentado em XVI International Symposium on Marine Natural Products |XI European Conference on Marine Natural Products, Peniche, 2019.
    Publicado • 10.3390/md18010040
  5. Viegas, Carla. "AMENTADIONE, A MERODITERPENOIDE FROM BROWN ALGAE WITH CAPACITY OF MODULATING OSTEOARTHRITIC RESPONSES, IN A CLOSE-TO-IN-VIVO OA MODEL". Trabalho apresentado em XVI International Symposium on Marine Natural Products |XI European Conference on Marine Natural Products, Peniche, 2019.
    Publicado • 10.3390/md18010040
  6. Devi, Meena; Awasthi, Shachi. "Nanoencapsulation as a novel delivery approach for therapeutic applications of gla-rich protein (GRP)". Trabalho apresentado em 4th congress of CiiEM on “Health, Well-Being and Ageing in the 21st Century, Almada, 2019.
  7. Silva, Ana Paula; Viegas, Carla; Simes, Dina; Mendes, Filipa; Tavares, Nelson; Rato, Fatima; Santos, Nelio; Neves, Pedro. "SP430GLA-RICH PROTEIN AS A NOVEL MARKER FOR CALCIFICATIONS IN DIABETIC PATIENTS WITH CKD". Trabalho apresentado em 55th ERA-EDTA Congress, Copenhagen, 2018.
    10.1093/ndt/gfy104.sp430
  8. Viegas, Carla; Santos, Lúcia; Macedo, Anjos; Morais, Rute; Silva, Ana; Neves, Pedro; Matos, António; Vermeer, Cees; Simes, Dina. "MO055CIRCULATING CALCIPROTEIN PARTICLES AND EXTRACELLULAR VESICLES AS NOVEL PLAYERS IN CHRONIC KIDNEY DISEASE VASCULAR CALCIFICATION. A ROLE FOR GLA-RICH PROTEIN". Trabalho apresentado em ERA-EDTA 54th Annual Congress, Madrid, 2017.
    10.1093/ndt/gfx123.mo055
  9. Viegas, Carla; Simes, DC; Cavaco, S; Costa, R.; Rafael, Marta; Laires, R; Marques, V; et al. "New Targets for therapeutics in osteoarthritis: Marine compounds and Gla rich proteins". Trabalho apresentado em 9th SFRR-Africa/4th IAMBR conference. Translational Science and Drug Discovery: Impact on Health, Wellness, Environment and Economics, 2015.
    Publicado
  10. Viegas, Carla; Rafael, Marta; Enriquez, J.L.; Teixeira, A; Vitorino, R; Costa, RM; Santos, LR; et al. "Gla-rich protein (GRP) is a new player in mineralization-competence of extracellular vesicles involved in vascular calcification". Trabalho apresentado em Joint Meeting of the European Society for Microcirculation (ESM) and European Vascular Biology Organization (EVBO), Pisa, 2015.
    Publicado
  11. Rafael, Marta; Cavaco, Sofia; Viegas, Carla; Santos, Sofia; Ramos, Acacio; Luis, Ines; Costa, Ruben; et al. "Involvement of Gla rich protein with pathological calcification during osteoarthritis. Insights into its ¿-carboxylation status". Trabalho apresentado em European Calcified Tissue Society, Prague, 2014.
    10.1530/boneabs.3.pp373
  12. Cavaco, S.I.; Viegas, C.B.; Marta, R.; Acácio, R.; Silva, J.; Morera, J.L.; Teixeira, A.; et al. "Gla rich protein (grp) is associated to osteoarthritis being highly accumulated in the joint tissues and synovial fluid". Trabalho apresentado em OARSI 2012 World Congress, Barcelona, 2012.
    10.1016/j.joca.2012.02.090
  13. Cavaco¿, S.I.; Viegas, C.; Cordeiro, O.; Vareilles, M.; Silva, T.; Palma, P.; Simes, D.. "Identification and characterization of GRP in articular cartilage and synovial fluid using a proteomic-based approach". Trabalho apresentado em 3rd Joint Meeting of the European Calcified Tissue Society & the International Bone and Mineral Society, Athenas, 2011.
    10.1016/j.bone.2011.03.652
  14. Viegas, Carla; Simes, Dina; Williamson, M.K.; Laizé, V.; Price, PA; Cancela, ML. "Identification of an hybrid gene in the Adriatic sturgeon (Acipenser naccarii), an ancient bony fish with a cartilaginous endoskeleton". Trabalho apresentado em 35th ECTS Meeting, Barcelona, 2008.
  15. Simes, Dina C.; Viegas, Carla B.; Williamson, Matthew K.; Price, Paul A.; Cancela, Leonor. "Purification of matrix Gla protein and osteocalcin from the adriatic sturgeon (Acipencer naccarii), an Ancient bony fish with a cartilaginous endoskeleton". Trabalho apresentado em The International Bone and Mineral Society, Davos, 2008.
    10.1016/j.bone.2007.12.116
  16. Viegas, Carla; Pearson, G; Serrão, EA; Cancela, ML. "Plastid Genes and Gene Expression in the Interdial Alga Fucus Vesiculosus L. (Heterokontophyta, Phaeophyceae)". Trabalho apresentado em 7th International Phycological Congress, Thessaloniki, 2001.
  17. Viegas, Carla; Gavaia, Paulo J; Pinto, J.P.; Sarasquete, C.; Cancela, ML. "Detection and localization of osteocalcin (BGP or Bone Gla Protein) in teleosts by in situ hybridization and immunohistochemistry.". Trabalho apresentado em 1st Joint Meeting of the International Bone and Mineral Society and the European Calcified Tissue Society, Madrid, 2001.
Artigo em jornal
  1. Viegas, Carla. "Novo biomarcador ajuda a detetar doenças cardiovasculares em doentes renais", Sul Informação, 2017, https://www.sulinformacao.pt/2017/11/novo-biomarcador-desenvolvido-pelo-ccmar-ajuda-a-detetar-doencas-cardiovasculares-em-doentes-renais/.
  2. Viegas, Carla. "Gla-rich protein is a novel vitamin K-dependent protein present in serum that accumulates at sites of pathological calcifications", Journal Club - Kidney International, 2010, https://www.kidney-international.org/article/S0085-2538(15)54262-2/fulltext.
Artigo em revista
  1. Marreiros, Catarina; Viegas, Carla; Guedes, Anabela Malho; Silva, Ana Paula; Águas, Ana Catarina; Faísca, Marília; Schurgers, Leon; Simes, Dina Costa. "Gla-Rich Protein Is Associated with Vascular Calcification, Inflammation, and Mineral Markers in Peritoneal Dialysis Patients". Journal of Clinical Medicine 13 23 (2024): 7429. https://doi.org/10.3390/jcm13237429.
    10.3390/jcm13237429
  2. Viegas, Carla; Carreira, Joana; Maia, Teresa M.; Macedo, Anjos L.; Matos, António P.; Neves, José; Simes, Dina. "Gla Rich Protein (GRP) Mediates Vascular Smooth Muscle Cell (VSMC) Osteogenic Differentiation, Extracellular Vesicle (EV) Calcification Propensity, and Immunomodulatory Properties". International Journal of Molecular Sciences 25 22 (2024): 12406. https://doi.org/10.3390/ijms252212406.
    10.3390/ijms252212406
  3. Pinto, Ezequiel; Viegas, Carla; Martins, Paula Ventura; Marreiros, Catarina; Nascimento, Tânia; Schurgers, Leon; Simes, Dina. "Mediterranean Diet Favors Vitamin K Intake: A Descriptive Study in a Mediterranean Population". Nutrients 16 8 (2024): 1098. http://dx.doi.org/10.3390/nu16081098.
    10.3390/nu16081098
  4. Pinto, Ezequiel; Viegas, Carla; Martins, Paula Ventura; Nascimento, Tânia; Schurgers, Leon; Simes, Dina. "New Food Frequency Questionnaire to Estimate Vitamin K Intake in a Mediterranean Population". Nutrients 15 13 (2023): 3012. http://dx.doi.org/10.3390/nu15133012.
    10.3390/nu15133012
  5. Marreiros, Catarina; Viegas, Carla; Simes, Dina. "Targeting a Silent Disease: Vascular Calcification in Chronic Kidney Disease". International Journal of Molecular Sciences 23 24 (2022): 16114. http://dx.doi.org/10.3390/ijms232416114.
    10.3390/ijms232416114
  6. Brancaccio, Mariarita; Milito, Alfonsina; Viegas, Carla Alexandra; Palumbo, Anna; Simes, Dina Costa; Castellano, Immacolata. "First evidence of dermo-protective activity of marine sulfur-containing histidine compounds". Free Radical Biology and Medicine 192 (2022): 224-234. http://dx.doi.org/10.1016/j.freeradbiomed.2022.09.017.
    10.1016/j.freeradbiomed.2022.09.017
  7. Silva, Mélanie; Kamberovic, Farah; Uota, Sisay Tesema; Kovan, Ismael-Mohammed; Viegas, Carla S. B.; Simes, Dina C.; Gangadhar, Katkam N.; Varela, João; Barreira, Luísa. "Microalgae as Potential Sources of Bioactive Compounds for Functional Foods and Pharmaceuticals". Applied Sciences 12 12 (2022): 5877. http://dx.doi.org/10.3390/app12125877.
    10.3390/app12125877
  8. Viegas, Carla S. B.; Araújo, Nuna; Carreira, Joana; Pontes, Jorge F.; Macedo, Anjos L.; Vinhas, Maurícia; Moreira, Ana S.; et al. "Nanoencapsulation of Gla-Rich Protein (GRP) as a Novel Approach to Target Inflammation". International Journal of Molecular Sciences 23 9 (2022): 4813. http://dx.doi.org/10.3390/ijms23094813.
    Acesso aberto • Publicado • 10.3390/ijms23094813
  9. Silva, Ana P.; Viegas, Carla S. B.; Guilherme, Patrícia; Tavares, Nelson; Dias, Carolina; Rato, Fátima; Santos, Nélio; et al. "Gla-Rich Protein, Magnesium and Phosphate Associate with Mitral and Aortic Valves Calcification in Diabetic Patients with Moderate CKD". Diagnostics 12 2 (2022): 496. http://dx.doi.org/10.3390/diagnostics12020496.
    10.3390/diagnostics12020496
  10. Araújo, Nuna; Viegas, Carla S. B.; Zubía, Eva; Magalhães, Joana; Ramos, Acácio; Carvalho, Maria M.; Cruz, Henrique; et al. "Amentadione from the Alga Cystoseira usneoides as a Novel Osteoarthritis Protective Agent in an Ex Vivo Co-Culture OA Model". Marine Drugs 18 12 (2020): 624. http://dx.doi.org/10.3390/md18120624.
    10.3390/md18120624
  11. Silva, Ana P; Viegas, Carla SB; Mendes, Filipa; Macedo, Ana; Guilherme, Patrícia; Tavares, Nelson; Dias, Carolina; et al. "Gla-Rich Protein (GRP) as an Early and Novel Marker of Vascular Calcification and Kidney Dysfunction in Diabetic Patients with CKD: A Pilot Cross-Sectional Study". Journal of Clinical Medicine 9 3 (2020): 635. http://dx.doi.org/10.3390/jcm9030635.
    10.3390/jcm9030635
  12. Simes, Dina C.; Viegas, Carla S. B.; Araújo, Nuna; Marreiros, Catarina. "Vitamin K as a Diet Supplement with Impact in Human Health: Current Evidence in Age-Related Diseases". Nutrients 12 1 (2020): 138. http://dx.doi.org/10.3390/nu12010138.
    10.3390/nu12010138
  13. Marreiros, Catarina; Ismael, Kovan; Viegas, Carla; Araujo, Nuna; Andrade, Miguel; Rosa, Bruno; Lima, Rui; et al. "Anti-Inflammatory Activity of Microalgae-Derived Bioactives with Potential Dermoprotective Apllications". Marine Drugs (2020): https://publons.com/publon/32337057/.
  14. Viegas, Carla; Silva, Ana; Macedo, Ana; Mendes, Filipa; Guilherme, Patricia; Tavares, Nelson; Dias, Carolina; et al. "GLA-RICH PROTEIN (GRP) AS AN EARLY AND NOVEL MARKER ASSOCIATED WITH VASCULAR CALCIFICATION AND CKD-MINERAL AND BONE DISORDER (MBD) IN DIABETIC PATIENTS WITH CKD: A PILOT COHORT STUDY". Nephrology Dialysis Transplantation (2020): https://publons.com/wos-op/publon/44427078/.
  15. Viegas, Carla; Edelweiss, Evelina; Schneider, Justine; Schaeffer-Reiss, Christine; Poterszman, Arnaud; Rafael, Marta; Araújo, Nuna; et al. "Use of an innovative system and nanotechnology-based strategy for therapeutic applications of Gla-rich protein (GRP)". Annals of Medicine 51 sup1 (2019): 38-38. http://dx.doi.org/10.1080/07853890.2018.1561804.
    10.1080/07853890.2018.1561804
  16. Araújo, Nuna; Viegas, Carla; Perrolas, Inês; Costa, Rúben; Magalhães, Joana; Blanco, Francisco; Ramos, Acácio; et al. "Amentadione is a new modulating agent for osteoarthritis in an ex-vivo co-culture preclinical assay". Annals of Medicine 51 sup1 (2019): 43-43. http://dx.doi.org/10.1080/07853890.2018.1561895.
    10.1080/07853890.2018.1561895
  17. Viegas, C.S.B.; Simes, D.C.. "A dual role for GRP in cardiovascular disease". Aging 11 5 (2019): 1323-1324. http://www.scopus.com/inward/record.url?eid=2-s2.0-85062969748&partnerID=MN8TOARS.
    10.18632/aging.101851
  18. Simes, D.C.; Viegas, C.S.B.; Araújo, N.; Marreiros, C.. "Vitamin K as a powerful micronutrient in aging and age-related diseases: Pros and cons from clinical studies". International Journal of Molecular Sciences 20 17 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85071762863&partnerID=MN8TOARS.
    10.3390/ijms20174150
  19. Viegas, C.; Araújo, N.; Marreiros, C.; Simes, D.. "The interplay between mineral metabolism, vascular calcification and inflammation in Chronic Kidney Disease (CKD): Challenging old concepts with new facts". Aging 11 12 (2019): 4274-4299. http://www.scopus.com/inward/record.url?eid=2-s2.0-85069006491&partnerID=MN8TOARS.
    10.18632/aging.102046
  20. Willems BA; Furmanik M; Caron MMJ; Chatrou MLL; Kusters DHM; Welting TJM; Stock M; et al. "Ucma/GRP inhibits phosphate-induced vascular smooth muscle cell calcification via SMAD-dependent BMP signalling.". Scientific reports (2018): http://europepmc.org/abstract/med/29563538.
    10.1038/s41598-018-23353-y
  21. Viegas CSB; Santos L; Macedo AL; Matos AA; Silva AP; Neves PL; Staes A; et al. "Chronic Kidney Disease Circulating Calciprotein Particles and Extracellular Vesicles Promote Vascular Calcification: A Role for GRP (Gla-Rich Protein).". Arteriosclerosis, thrombosis, and vascular biology (2018): http://europepmc.org/abstract/med/29301790.
    10.1161/atvbaha.117.310578
  22. Viegas, Carla. "Gla-rich protein, a vitamin K-dependent protein involved in inflammation and calcification-related diseases". Annals of Medicine 50 supl 1 (2018):
    Publicado
  23. Viegas CS; Macedo AL; Morais R; Santos L; Matos AP; Silva AP; Neves P; Simes DC. "Dysregulated fetuin-mineral complexes are linked to vascular calcification in chronic kidney disease: The role of Gla-rich protein.". (2017): http://europepmc.org/abstract/med/28230466.
    10.1080/01913123.2016.1269490
  24. Morais R; Viegas CS; Simes DC; Matos AP; Macedo AL. "Application of TEM techniques for the study of vascular calcification: Monitoring extracellular vesicles and nanogold immunodetection of fetuin-A, GRP, and CD9.". (2017): http://europepmc.org/abstract/med/28230494.
    10.1080/01913123.2016.1272670
  25. Viegas CSB; Costa RM; Santos L; Videira PA; Silva Z; Araújo N; Macedo AL; et al. "Gla-rich protein function as an anti-inflammatory agent in monocytes/macrophages: Implications for calcification-related chronic inflammatory diseases.". (2017): http://europepmc.org/abstract/med/28542410.
    10.1371/journal.pone.0177829
  26. Viegas, Carla; Santos, Lucia; Macedo, Anjos; Morais, Rute; Silva, Ana; Neves, Pedro; Matos, Antonio; Vermeer, Cees; Simes, Dina. "CIRCULATING CALCIPROTEIN PARTICLES AND EXTRACELLULAR VESICLES AS NOVEL PLAYERS IN CHRONIC KIDNEY DISEASE VASCULAR CALCIFICATION. A ROLE FOR GLA-RICH PROTEIN". Nephrology Dialysis Transplantation (2017): https://publons.com/publon/28689989/.
  27. Cavaco S; Viegas CS; Rafael MS; Ramos A; Magalhães J; Blanco FJ; Vermeer C; Simes DC. "Gla-rich protein is involved in the cross-talk between calcification and inflammation in osteoarthritis.". (2016): http://europepmc.org/abstract/med/26337479.
    10.1007/s00018-015-2033-9
  28. Viegas, C.S.B.; Rafael, M.S.; Enriquez, J.L.; Teixeira, A.; Vitorino, R.; Luís, I.M.; Costa, R.M.; et al. "Gla-rich protein acts as a calcification inhibitor in the human cardiovascular system". Arteriosclerosis, Thrombosis, and Vascular Biology 35 2 (2016): 399-408. http://www.scopus.com/inward/record.url?eid=2-s2.0-84922014561&partnerID=MN8TOARS.
    10.1161/ATVBAHA.114.304823
  29. MacEdo, A.L.; Viegas, C.S.B.; Matos, A.P.A.; Simes, D.C.. "Extracellular vesicles and circulating fetuin-mineral complexes in vascular calcification; Studies by em techniques". Microscopy and Microanalysis 22 (2016): 16-17. http://www.scopus.com/inward/record.url?eid=2-s2.0-85014510834&partnerID=MN8TOARS.
    10.1017/S1431927616000271
  30. Viegas, Carla SB; Simes, Dina C. "New Perspectives for the Nutritional Value of Vitamin K in Human Health". Journal of Nutritional Disorders & Therapy 6 3 (2016): http://dx.doi.org/10.4172/2161-0509.1000192.
    10.4172/2161-0509.1000192
  31. Viegas, Carla SB; Simes, Dina C. "Gla-rich Protein (GRP): A New Player In The Burden Of Vascular Calcification". Journal of Cardiovascular Diseases & Diagnosis 4 4 (2016): http://dx.doi.org/10.4172/2329-9517.1000245.
    10.4172/2329-9517.1000245
  32. Rafael, M.S.; Cavaco, S.; Viegas, C.S.B.; Santos, S.; Ramos, A.; Willems, B.A.G.; Herfs, M.; et al. "Insights into the association of Gla-rich protein and osteoarthritis, novel splice variants and ¿-carboxylation status". Molecular Nutrition and Food Research 58 8 (2014): 1636-1646. http://www.scopus.com/inward/record.url?eid=2-s2.0-84905370679&partnerID=MN8TOARS.
    10.1002/mnfr.201300941
  33. Viegas, C.S.B.; Herfs, M.; Rafael, M.S.; Enriquez, J.L.; Teixeira, A.; Luís, I.M.; Van 'T Hoofd, C.M.R.; et al. "Gla-rich protein is a potential new vitamin K target in cancer: Evidences for a direct GRP-mineral interaction". BioMed Research International 2014 (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84902129958&partnerID=MN8TOARS.
    10.1155/2014/340216
  34. Silva, A.P.; Fragoso, A.; Silva, C.; Viegas, C.; Tavares, N.; Guilherme, P.; Santos, N.; et al. "What is the role of apelin regarding cardiovascular risk and progression of renal disease in type 2 diabetic patients with diabetic nephropathy?". BioMed Research International 2013 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84884882775&partnerID=MN8TOARS.
    10.1155/2013/247649
  35. Viegas, C.S.B.; Simes, D.C.; Williamson, M.K.; Cavaco, S.; Laizé, V.; Price, P.A.; Cancela, M.L.. "Sturgeon osteocalcin shares structural features with matrix Gla protein: Evolutionary relationship and functional implications". Journal of Biological Chemistry 288 39 (2013): 27801-27811. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884788467&partnerID=MN8TOARS.
    10.1074/jbc.M113.450213
  36. Viegas, C.S.B.; Conceiçao, N.; Fazenda, C.; Simes, D.C.; Cancela, M.L.. "Expression of Gla-rich protein (GRP) in newly developed cartilage-derived cell cultures from sturgeon (Acipenser naccarii)". Journal of Applied Ichthyology 26 2 (2010): 214-218. http://www.scopus.com/inward/record.url?eid=2-s2.0-77954186984&partnerID=MN8TOARS.
    10.1111/j.1439-0426.2010.01408.x
  37. Le Corguillé, G.; Pearson, G.; Valente, M.; Viegas, C.; Gschloessl, B.; Corre, E.; Bailly, X.; et al. "Plastid genomes of two brown algae, Ectocarpus siliculosus and Fucus vesiculosus: Further insights on the evolution of red-algal derived plastids". BMC Evolutionary Biology 9 1 (2009): http://www.scopus.com/inward/record.url?eid=2-s2.0-70449135018&partnerID=MN8TOARS.
    10.1186/1471-2148-9-253
  38. Roberto, V.P.; Cavaco, S.; Viegas, C.S.B.; Simes, D.C.; Ortiz-Delgado, J.-B.; Sarasquete, M.C.; Gavaia, P.J.; Cancela, M.L.. "Matrix Gla protein in turbot (Scophthalmus maximus): Gene expression analysis and identification of sites of protein accumulation". Aquaculture 294 3-4 (2009): 202-211. http://www.scopus.com/inward/record.url?eid=2-s2.0-67749143948&partnerID=MN8TOARS.
    10.1016/j.aquaculture.2009.06.020
  39. Viegas, C.S.B.; Cavaco, S.; Neves, P.L.; Ferreira, A.; João, A.; Williamson, M.K.; Price, P.A.; Cancela, M.L.; Simes, D.C.. "Gla-rich protein is a novel vitamin K-dependent protein present in serum that accumulates at sites of pathological calcifications". American Journal of Pathology 175 6 (2009): 2288-2298. http://www.scopus.com/inward/record.url?eid=2-s2.0-73549121071&partnerID=MN8TOARS.
    10.2353/ajpath.2009.090474
  40. Viegas, C.S.B.; Simes, D.C.; Laizé, V.; Williamson, M.K.; Price, P.A.; Cancela, M.L.. "Gla-rich protein (GRP), a new vitamin K-dependent protein identified from sturgeon cartilage and highly conserved in vertebrates". Journal of Biological Chemistry 283 52 (2008): 36655-36664. http://www.scopus.com/inward/record.url?eid=2-s2.0-61349170719&partnerID=MN8TOARS.
    10.1074/jbc.M802761200
  41. Rønnestad, I.; Gavaia, P.J.; Viegas, C.S.B.; Verri, T.; Romano, A.; Nilsen, T.O.; Jordal, A.-E.O.; Kamisaka, Y.; Cancela, M.L.. "Oligopeptide transporter PepT1 in Atlantic cod (Gadus morhua L.): Cloning, tissue expression and comparative aspects". Journal of Experimental Biology 210 22 (2007): 3883-3896. http://www.scopus.com/inward/record.url?eid=2-s2.0-37249063715&partnerID=MN8TOARS.
    10.1242/jeb.007898
  42. Simões, B.; Conceição, N.; Viegas, C. S. B.; Pinto, J. P.; Gavaia, P. J.; Hurst, L. D.; Kelsh, R. N.; Cancela, M. L.. "Identification of a Promoter Element within the Zebrafish colXa1 Gene Responsive to Runx2 Isoforms Osf2/Cbfa1 and til-1 but not to pebp2aA2". Calcified Tissue International 79 4 (2006): 230-244. http://dx.doi.org/10.1007/s00223-006-0111-6.
    10.1007/s00223-006-0111-6
  43. Simões, B.; Conceição, N.; Viegas, C.S.B.; Pinto, J.P.; Gavaia, P.J.; Hurst, L.D.; Kelsh, R.N.; Cancela, M.L.. "Identification of a promoter element within the Zebrafish colXa1 gene responsive to Runx2 isoforms Osf2/Cbfa1 and til-1 but not to pebp2aA2". Calcified Tissue International 79 4 (2006): 230-244. http://www.scopus.com/inward/record.url?eid=2-s2.0-33750561072&partnerID=MN8TOARS.
    10.1007/s00223-006-0111-6
  44. Gavaia, P.J.; Simes, D.C.; Ortiz-Delgado, J.B.; Viegas, C.S.B.; Pinto, J.P.; Kelsh, R.N.; Sarasquete, M.C.; Cancela, M.L.. "Osteocalcin and matrix Gla protein in zebrafish (Danio rerio) and Senegal sole (Solea senegalensis): Comparative gene and protein expression during larval development through adulthood". Gene Expression Patterns 6 6 (2006): 637-652. http://www.scopus.com/inward/record.url?eid=2-s2.0-33646862665&partnerID=MN8TOARS.
    10.1016/j.modgep.2005.11.010
  45. Ortiz-Delgado, J.B.; Simes, D.C.; Viegas, C.S.B.; Schaff, B.J.; Sarasquete, C.; Cancela, M.L.. "Cloning of matrix Gla protein in a marine cartilaginous fish, Prionace glauca: Preferential protein accumulation in skeletal and vascular systems". Histochemistry and Cell Biology 126 1 (2006): 89-101. http://www.scopus.com/inward/record.url?eid=2-s2.0-33745063198&partnerID=MN8TOARS.
    10.1007/s00418-005-0125-6
  46. Laizé, V.; Viegas, C.S.B.; Price, P.A.; Cancela, M.L.. "Identification of an osteocalcin isoform in fish with a large acidic prodomain". Journal of Biological Chemistry 281 22 (2006): 15037-15043. http://www.scopus.com/inward/record.url?eid=2-s2.0-33744965092&partnerID=MN8TOARS.
    10.1074/jbc.M600373200
  47. Pinto, J.P.; Conceição, N.M.; Viegas, C.S.B.; Leite, R.B.; Hurst, L.D.; Kelsh, R.N.; Cancela, M.L.. "Identification of a new pebp2aA2 isoform from Zebrafish runx2 capable of inducing osteocalcin gene expression in vitro". Journal of Bone and Mineral Research 20 8 (2005): 1440-1453. http://www.scopus.com/inward/record.url?eid=2-s2.0-22744449747&partnerID=MN8TOARS.
    10.1359/JBMR.050318
  48. Laizé, V.; Martel, P.; Viegas, C.S.B.; Price, P.A.; Cancela, M.L.. "Evolution of matrix and bone ¿-carboxyglutamic acid proteins in vertebrates". Journal of Biological Chemistry 280 29 (2005): 26659-26668. http://www.scopus.com/inward/record.url?eid=2-s2.0-22844440951&partnerID=MN8TOARS.
    10.1074/jbc.M500257200
  49. Simes, D.C.; Williamson, M.K.; Ortiz-Delgado, J.B.; Viegas, C.S.B.; Price, P.A.; Cancela, M.L.. "Purification of matrix Gla protein from a marine teleost fish, Argyrosomus regius: Calcified cartilage and not bone as the primary site of MGP accumulation in fish". Journal of Bone and Mineral Research 18 2 (2003): 244-259. http://www.scopus.com/inward/record.url?eid=2-s2.0-12244249480&partnerID=MN8TOARS.
    10.1359/jbmr.2003.18.2.244
  50. Viegas, C.S.B.; Pinto, J.P.; Conceição, N.; Simes, D.C.; Cancela, M.L.. "Cloning and characterization of the cDNA and gene encoding Xenopus laevis osteocalcin". Gene 289 1-2 (2002): 97-107. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036572833&partnerID=MN8TOARS.
    10.1016/S0378-1119(02)00480-8
  51. Cancela, M.L.; Ohresser, M.C.P.; Reia, J.P.; Viegas, C.S.B.; Williamson, M.K.; Price, P.A.. "Matrix Gla protein in Xenopus laevis: Molecular cloning, tissue distribution, and evolutionary considerations". Journal of Bone and Mineral Research 16 9 (2001): 1611-1621. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034868048&partnerID=MN8TOARS.
Artigo em revista (magazine)
  1. Viegas, Carla; Catarina Marreios; Professora Doutora Dina Simes. "A relação entre a doença renal crónica e complicações cardiovasculares – será a proteína GRP a solução?", UALGoritmo, A Ciência Trocada por Miúdos, 2020
  2. Viegas, Carla; Catarina Marreiros; Professora Doutora Dina Simes. "A relação entre a doença renal crónica e complicações cardiovasculares-será a proteína GRP a solução?", Ualgoritmo, 2020, https://ualgoritmo.wixsite.com/website.
Capítulo de livro
  1. Viegas, Carla S.B.; Simes, Dina C.. "Inflammation and Calcification in the Vascular Tree; Insights Into Atherosclerosis". In Immunity and Inflammation in Health and Disease, 189-201. Elsevier, 2018.
    10.1016/b978-0-12-805417-8.00015-9
Entrada de enciclopédia
  1. Professora Doutora Dina Simes; Viegas, Carla; Catarina Marreiros; Araújo, Nuna. "https://encyclopedia.pub/511". In Encyclopedia Scholarly Community Encyclopedia, 2020.
    Publicado
  2. Ana Silva; Viegas, Carla; Professora Doutora Dina Simes. "Gla-Rich Protein in CKD.". In Encyclopedia Scholarly Community Encyclopedia, 2020.
    Publicado
Poster em conferência
  1. SIMES DC; Viegas, Carla; Varela, João; Dorit Avni; Silva, Mélanie; Barreira, Luísa. "A PATHWAY TOWARDS BETTER HEALTH: FIGHTING INFLAMMATION WITH NOVEL MICROALGAE-BASED NATURAL COMPOUNDS". Trabalho apresentado em ALGAEUROPE 2023, 2023.
  2. Dorit Avni; Nathalie Shagug; Y Eilam; Antonio Marzochella; Daria Maria Monti; Antonino Pollio; Barreira, Luísa; et al. "ALGAE AS A SUSTAINABLE FOOD BRIDGES THE REALMS OF HEALTH AND ENVIRONTMENTAL". Trabalho apresentado em ALGAEUROPE 2023, 2023.
  3. Catarina Marreiros; Viegas, Carla; Guedes A; Silva AP; Faísca M; Schurgers L; Simes DC. "Reference intervals for Gla Rich Protein serum levels and variations a in peritoneal dialysis population". Trabalho apresentado em 6th International Scientific Congress of CiiEM - Immediate and future challenges to foster One Health, 2023.
  4. Viegas, Carla; Ana Paula Silva; Marilia Faisca; Schurgers, Leon; Simes, Dina. "Establishment of Reference Intervals for Gla Rich Protein Serum levels and variations in a Peritoneal Dialysis Population". Trabalho apresentado em Egas Moniz International Scientific Congress (CiiEM), 2023.
  5. Viegas, Carla; Carreira J; Maia T; Dufour S; Impens F; Macedo AL; Matos AP; Simes DC. "Calcifying extracellular vesicles containing Gla-rich protein (GRP) modulate inflammatory responses in human macrophages". Trabalho apresentado em Second Meeting of the Portuguese Network on Extracellular Vesicles (PNEV), 2023.
  6. Mélanie S; Farah K; Sisay U; Ismael-Mohammed K; Viegas, Carla; Professora Doutora Dina Simes; Katkam G; João V; Luísa B. "Commercially produced microalgae as sources of bioactive compounds for functional foods and pharmaceuticals.". Trabalho apresentado em AlgaEurope 2022, 2022.
  7. Viegas, Carla; Carreira, Joana; Dufour S; Impens F; Macedo A; Matos A; Professora Doutora Dina Simes. "Deciphering the complexity of extracellular vesicles (EVs) mediated vascular calcification using a proteomic approach.". Trabalho apresentado em ProteoVilamoura, 2nd Joint Meeting of Spanish, French and Portuguese Proteomics Societies, 2022.
  8. "Preliminary Structural characterization of human Gla Rich Protein involved in the inhibition of mineral crystal formation in vascular calcification.". Trabalho apresentado em XXI National Congress of Biochemistry, 2021.
  9. "Exploring the potential of the microalgae tetraselmis striata ctp4 as a novel source of anti-inflammatory compounds.". Trabalho apresentado em XII European Conference on Marine Natural Products, 2021.
  10. "Projeto piloto para criação de um questionário de frequência alimentar para determinar aporte de vitamina K numa população mediterrânica". Trabalho apresentado em 1º Congresso da Rede de Instituições do Ensino Superior para a Salvaguarda da Dieta Mediterrânica, 2021.
  11. Viegas, Carla; Marreiros, C.; Ismael, K.; Araújo, N.; Andrada, M.; Rosa, B.; Lima, R.; et al. "Anti-inflammatory Activity of Microalgae-derived Bioatives with Dermoprotective Application". Trabalho apresentado em Joint XVI International Symposium on Marine Natural Products and XI European Conference on Marine Natural Products, 2019.
  12. Viegas, Carla; Brancacciol, M.; Millitol, A.; Simes, DC.. "Marine 5-thiohistidines as protective molecules from skin damage". Trabalho apresentado em The 44th FEBS Congress, 2019.
  13. Brancaccio, M.; Viegas, C (C414-F596-EEC6); Milito, A.; Simes, DC.; Castellano, I.. "Therapeutic potential of 5-thiohistidines in human inflammatory diseases". Trabalho apresentado em 2° Workshop BIO/10, 2019.
    10.1063/1.5061918
  14. Viegas, Carla; Silva, AP.; Simes, DC.; Mendes, F.; Tavares, N.; Rato, F.; Santos, N.; Neves, PL.. "Gla-Rich Protein as a novel marker for calcifications in diabetic patients with CKD". Trabalho apresentado em 55th ERA-EDTA Congress, 2018.
  15. Viegas, Carla; Araújo, N.; Pontes, JF.; Magalhães, J.; Blanco, FJ.; Macedo, AL.; Grenha, A.; Simes, DC.. "Nano-encapsulation of Gla-rich protein (GRP) and potential added value as a therapeutic agent for osteoarthritis". Trabalho apresentado em 21st International Symposium on Microencapsulation, 2017.
  16. Viegas, Carla; Araújo, N.; Costa, R.; Ramos, A.; Zubia, E.; Simes, DC.. "Exploring meroterpenoids from brown algae as novel therapeutic drugs for osteoarthritis". Trabalho apresentado em XV International Symposium on Marine Natural Products, 2016.
  17. Viegas, Carla; Morais, R.; Simes, DC.; Matos, AP.; Macedo, AL.. "Application of TEM Techniques for the Study of Vascular Calcification: Monitoring Extracellular Vesicles and NanoGold Immunodection of Fetuin-A, GRP and CD9.". Trabalho apresentado em Ultrapath XVII, Society for Ultrastructural Patholog, 2016.
  18. Viegas, Carla; Morais, R.; Macedo, AL.; Matos, AP.; Simes, DC.. "Electron Microscopy Contribution to the Study of Vascular Calcification Process: Monitoring Extracellular Vesicles Biogenesis and Mineralization". Trabalho apresentado em First International Congress of CiiEM. From Basic Sciences to Clinical Research, 2015.
  19. Viegas, Carla; Macedo, AL.; Matos, AP.; Simes, DC.. "Extracellular Vesicles and Circulating Fetuin-Mineral Complexes in Vascular Calcification; Studies by EM Techniques". Trabalho apresentado em 4th Joint Congress of the Portuguese and Spanish Microscopy Societies: Microscopy at the Frontiers of Science (MFS), 2015.
  20. Viegas, Carla; Costa, RM.; Rafael, MS.; Marques, G.; Silva, Z.; Videira, P.; Simes, DC.. "Study of mineralization-related vitamin K-dependent proteins associated with leukocytes in mineralization and inflammatory processes". Trabalho apresentado em XVIII Congress of the Portuguese Biochemical Society, 2014.
  21. Viegas, Carla; Santos, LR.; Rafael, MS.; Simes, DC.. "Studies towards unveiling potential interaction partners of Gla-rich protein (GRP), a potential regulator of pathological calcification related diseases". Trabalho apresentado em XVIII Congress of the Portuguese Biochemical Society, 2014.
  22. Viegas, Carla; Rafael, MS.; Cavaco, S.; Santos, S.; Ramos, A.; Luis, IM.; Costa, R.; et al. "Involvement of Gla rich protein (GRP) with pathological calcification during osteoarthritis. Insights into its y-carboxylation status". Trabalho apresentado em European Calcified Tissue Society, 2014.
  23. Viegas, Carla; Rafael, MS.; Ferrer-Miralles, N.; Vermeer, C.; Simes, DC.. "Production of functional recombinant Gla-rich protein (GRP) for clinical diagnosis". Trabalho apresentado em Practical workshop on Production, purification and characterization of macromolecular complexes, 2012.
  24. Viegas, Carla; Cavaco, S.; Rafael, MS.; Ramos, A.; Morera, JL.; Teixeira, A.; Smit, E.; et al. "Gla rich protein (GRP) is associated to osteoarthritis being highly accumulated in the joint tissues and synovial fluid". Trabalho apresentado em OARSI 2012 World Congress, 2012.
  25. Viegas, Carla; Cavaco, S.; Ramos, A.; Silva, J.; Morera, J.; Teixeira, A.; Smit, E.; et al. "Insights into the relation between Gla rich protein (GRP) and Osteoarthritis". Trabalho apresentado em FASEB Summer Research Conferences on Molecular, Structural & Clinical Aspects of Vitamin K & Vitamin K Dependent Proteins, 2011.
  26. Viegas, Carla; Morera, J.; Teixeira, A.; Joao, A.; Ferreira, A.; Neves, P.; Smit, E.; et al. "GRP is a new VKD protein associated with ectopic calcifications and potential application in clinical diagnostics". Trabalho apresentado em FASEB Summer research conferences- Molecular, Structural and clinical aspects of Vitamin K and Vitamin K dependent Proteins, 2011.
  27. Viegas, Carla; Smit, E.; Herfs, M.; Simes, DC.; Vermeer, C.. "GRP: a new Vitamin K dependent protein, immunolocalization in various human tissues". Trabalho apresentado em FASEB Summer research conferences- Molecular, Structural and clinical aspects of Vitamin K and Vitamin K dependent Proteins, 2011.
  28. Viegas, Carla; Cavaco, S.; Cordeiro, OD.; Vareilles, MC.; Silva, TS.; Palma, PF.; Simes, DC.. "Identification and characterization of GRP in articular cartilage and synovial fluid using a proteomic-based approach". Trabalho apresentado em 3rd Joint Meeting of the European Calcified Tissue Society & the International Bone and Mineral Society, 2011.
  29. Viegas, Carla; Cavaco, S.; Simes, DC.. "2-DE Proteomics of human articular cartilage for the identification of osteoarthritis biomarkers - procedures optimization". Trabalho apresentado em 4th EUPA meeting and 6th ProCura meeting, 2010.
  30. Viegas, Carla; Cavaco, S.; Neves, PL.; Ferreira, A.; Joao, A.; Williamson, MK.; Price, PA.; Cancela, ML.; Simes, DC.. "GRP is a New Vitamin K Dependent Protein and a Possible Ectopic Calcification Biomarker with Diagnostic Implications". Trabalho apresentado em BIT’s 3rd Annual Protein and Peptide Conference, 2010.
  31. Viegas, Carla; Fazenda, C.; Conceiçao, N.; Simes, DC.; Cancela, ML.. "Development of molecular and cellular tools to study the function of skeletal Gla-containg proteins in sturgeon". Trabalho apresentado em Workshop - Interdisciplinary Approaches in Fish Skeletal Biology, 2009.
  32. Viegas, Carla; Laize, V.; Simes, DC.; Cancela, ML.. "Evolutionary relationship of bone-associated Gla proteins". Trabalho apresentado em 2nd meeting of the European Society for Evolutionary Development Biology, 2008.
  33. Viegas, Carla; Simes, DC.; Williamson, MK.; Laize, V.; Price, PA.; Cancela, ML.. "Identification of an hybrid gene in the Adriatic sturgeon (Acipenser naccarii), an ancient bony fish with a cartilaginous endoskeleton". Trabalho apresentado em 35th ECTS Meeting, 2008.
  34. Viegas, Carla; Simes, DC.; Williamson, MK.; Price, PA.; Cancela, ML.. "Purification of Matrix Gla Protein and Osteocalcin from the Adriatic sturgeon (Acipencer naccarii), an ancient bony fish with a cartilaginous endoskeleton". Trabalho apresentado em The International Bone and Mineral Society, 2008.
  35. Viegas, Carla; Simes, DC.; Williamson, MK.; Price, PA.; Cancela, ML.. "Purification of Matrix Gla Protein and Osteocalcin from the Adriatic sturgeon (Acipencer naccarii), an ancient bony fish with a cartilaginous endoskeleton". Trabalho apresentado em The International Bone and Mineral Society, 2008.
  36. Viegas, Carla; Gavaia, P.; Simes, DC.; Cancela, ML.. "Molecular cloning and regulation of the genes encoding Matrix and Bone Gla proteins from Sturgeon. Studies towards understanding the evolution of their molecular mechanism of action". Trabalho apresentado em Seminários Mar e Ambiente, 2006.
  37. Viegas, Carla; Laize, V.; Martel, P.; Cancela, ML.. "Conserved Features of Matrix and Bone Gamma-Carboxyglutamic Acid Proteins in Vertebrates - An Evolutionary Point of View". Trabalho apresentado em 2nd Joint Meeting f the European Calcified Tissue Society (ECTS) and International Bone and Mineral Society (IBMS), 2005.
  38. Viegas, Carla; Mariani, V.; Gavaia, PJ.; Cancela, ML.; Giuffra, E.. "Comparative Analysis of Gene Expression Profiles Among Distantly Related Fish Species. Insight into Skeletal and Immunological Systems". Trabalho apresentado em XIII Conference on Plant & Animal Genomes, 2005.
  39. Viegas, Carla; Brito, A.; Ronnestad, I.; Cancela, ML.. "Expression of the oligopeptide transporter PepT1 (solute carrier family 15, member1) in fed and starved larvae of zebra fish (Danio rerio)". Trabalho apresentado em XIV Congresso Nacional de Bioquímica, 2004.
  40. Viegas, Carla; Ronnestad, I.; Gavaia, PJ.; Cancela, ML.. "Cloning and ontogenic expression of the oligopeptide transporter PepT1 (solute carrier family 15, member1) in fed and starved larvae of atlantic cod, Gadus morhua L.". Trabalho apresentado em XIV Congresso Nacional de Bioquímica, 2004.
  41. Viegas, Carla; Gavaia, PJ.; Ortiz-Delgado, JB.; Sarasquete, C.; Cancela, ML.. "Gla proteins as markers for studies of skeletal development and malformations in new aquaculture species (Pagrus auriga, Diplodus sargo and Scophtalmus maximus)". Trabalho apresentado em XIV Congresso Nacional de Bioquímica, 2004.
  42. Viegas, Carla; Simes, DC.; Ortiz-Delgado, JB.; Schaff, B.; Cancela, ML.. "Cloning of matrix Gla protein in a marine cartilaginous fish, Prionace glauca: identification of sites of mRNA and protein accumulation at single cell resolution". Trabalho apresentado em XIV Congresso Nacional de Bioquímica, 2004.
  43. Viegas, Carla; Simões, B.; Conceiçao, N.; Pinto, J.; Cancela, ML.. "Molecular cloning of the zebra fish (Danio rerio) Collagen Xa1 cDNA and gene. Identification of promoter regulatory elements". Trabalho apresentado em XIV Congresso Nacional de Bioquímica, 2004.
  44. Viegas, Carla; Pinto, J.; Conceiçao, N.; Leite, R.; Kelsh, R.; Cancela, ML.. "Identification of a new pebp2aA2 isoform from zebrafish runx2 capable of inducing osteocalcin gene expression in vitro". Trabalho apresentado em XIV Congresso Nacional de Bioquímica, 2004.
  45. Viegas, Carla; Gavaia, P.; Laize, V.; Mariani, V.; Giuffra, E.; Cancela, ML.. "Comparative analysis of gene expression profiles among distantly related fish species. Insight into skeletal and immunological systems". Trabalho apresentado em Marine Genomics Europe Kick-off Meeting, 2004.
  46. Viegas, Carla; Pearson, GA.; Serrão, EA.; Cancela, ML.. "Plastid genes and gene expression in the intertidal alga Fucus vesiculosus L. (heterokontophyta, phaeophyceae)". Trabalho apresentado em 7th International Phycological Congress, 2001.
  47. Viegas, Carla; Pearson, GA.; Serrão, EA.; Cancela, ML.. "Plastid genes and gene expression in the intertidal alga Fucus vesiculosus L. (heterokontophyta, phaeophyceae)". Trabalho apresentado em 27th FEBS Meeting, 2001.
  48. Viegas, Carla; Pinto, J.; Simes, DC.; Rodrigues, P.; Macedo, A.; Goodfellow, B.; Cancela, ML.. "Identification of invariant amino acid residues in BGP from fish to mammals suggests a conserved function throughout vertebrate evolution". Trabalho apresentado em 20th Conference of European Comparative Endocrinologists, 2000.
  49. Viegas, Carla; Lopes, EP.; Pinto, J.; Cancela, ML.. "Bone Gla protein in Xenopus laevis: molecular cloning and tissue distribution". Trabalho apresentado em XII Congresso Nacional de Bioquímica, 2000.
Resumo em conferência
  1. Araújo, Nuna; Viegas, Carla; MARREIROS, CATARINA; Simes, Dina. "Amentadione, a meroditerpenoide from brown algae with capacity of modulating osteoarthritis responses, in a close-to-in-vivo OA model". Trabalho apresentado em Joint XVI International Symposium on Marine Natural Products and XI European Conference on Marine Natural Products, Peniche, Leiria, 2019.
    Publicado

Propriedade Intelectual

Pedido provisório de patente
  1. 2008. "A gammacarboxyglutamate-rich protein, methods and assays for its detection, purification and quantification and uses thereof.".

Outros

Empresa spin-off
  1. 2009. GenoGla Diagnostics. http://www.genogla.com/.
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2024/10/11 Gla-Rich Protein-loaded EVs for cardiovascular research: Production via baculovirus-insect and human cell systems. 2nd MOVE Symposium
Several Societies of Extracellular Vesicles (Belgrade, Sérvia)
2024/01/26 Gla rich protein as a potential biochemical marker for cardiovascular risk assessment in peritoneal dialysis patients IX Clinical Biochemistry Workshop
Sociedade Portuguesa de Bioquímica (Faro, Portugal)
2024/01/26 Vitamin K potential as an anti-aging supplement with antioxidant and anti-inflammatory activity. IX Clinical Biochemistry Workshop
Sociedade Portuguesa de Bioquímica (Faro, Portugal)
2023/12/20 Engineered Extracellular Vesicles loaded with Gla-Rich Protein as nanotherapeutics for cardiovascular and chronic kidney diseases Annual Meeting of Doctoral Students in Biomedical Science
University of Algarve (Faro, Portugal)
2023/12/19 Studies towards the establishment of Gla Rich Protein (GRP) as a biomarker for cardiovascular risk assessment Annual Meeting of Doctoral Students in Biomedical Science
University of Algarve (Faro, Portugal)
2023/11/28 Ciência cidadã para estudar na população portuguesa a adesão á dieta mediterrânica e o aporte de vitamina K na dieta 4º Encontro Nacional de Ciência Cidadã (ENCC 2023)
Universidade de Coimbra (Coimbra, Portugal)
2023/11/16 Gla-Rich Protein (GRP) serum levels associate with Left Ventricle Hypertrophy and Pulse Pressure in PD patients Encontro Renal-Sociedade Portuguesa de Nefrologia (SNP)
Sociedade Portuguesa de Nefrologia (SNP) (Porto, Portugal)
2023/11/16 Gla-Rich Protein (GRP) as a Marker of Vascular Calcification and Inflammation in a Peritoneal Dialysis Population Encontro Renal-Sociedade Portuguesa de Nefrologia (SNP)
Sociedade Portuguesa de Nefrologia (SNP) (Porto, Portugal)
2023/07/14 Vitamin K intake and Mediterranean Diet: preliminary results of a Portuguese populational survey Nutrisafe Workshop - Valorisation of invasive seaweed biomass to develop new products for the blue bioeconomy
University of Algarve (Faro, Portugal)
2023/07/14 Exploring invasive macroalgae as a biomass source for a novel and sustainable vitamin K1 diet supplement Nutrisafe Workshop - Valorisation of invasive seaweed biomass to develop new products for the blue bioeconomy
University of Algarve (Faro, Portugal)
2023/07/14 In vitro studies for screening and validation of relevant bioactivities from algae-derived products Nutrisafe Workshop - Valorisation of invasive seaweed biomass to develop new products for the blue bioeconomy
University of Algarve (Faro, Portugal)
2023/07/05 Vitamin K intake and Mediterranean Diet: preliminary results of a Portuguese populational survey 6th International Scientific Congress of CiiEM - Immediate and future challenges to foster One Health
CiiEM (Monte da Caparica, Portugal)
2023/06/23 Exploring the therapeutic application of Gla-rich protein (GRP) in chronic inflammatory diseases using bioengineered nanovesicles Second Meeting of the Portuguese Network on Extracellular Vesicles (PNEV)
NOVA Medical School, Lisbon, Portugal (Lisbon, Portugal)
2022/12/07 Novel approaches to manage chronic inflammatory diseases: the therapeutic and biomarker potential of Gla-Rich Protein (GRP). International Conference Aging without Borders
(Faro, Portugal)
2022/12/06 Preclinical studies to validate novel therapeutics to prevent and treat chronic inflammatory diseases associated with ageing. International Conference Aging without Borders
(Faro, Portugal)
2022/11/19 Application of Gla-rich Protein (GRP) in diagnostic and therapeutic of cardiovascular disease in Chronic Kidney Disease (CKD) patients: the therapeutic perspective and approach. Encontro Renal 2022
(Vilamoura, Portugal)
2022/11/18 Os velhos e os novos fatores preditivos de risco cardiovascular na doença renal crónica: rácio cálcio/magnésio e GRP/EVs sérica. Encontro Renal 2022
(Vilamoura, Portugal)
2022/10/10 Os velhos e os novos fatores preditivos de risco cardiovascular na doença renal crónica: rácio cálcio/magnésio e GRP/EVs sérica. 2º Encontro de Nefrologia Translacional
(Setúbal, Portugal)
2022/09/22 Preclinical studies of bioactive compounds using human in vitro/ex vivo models to advance drug development. International Summer School of Blue Biotechnology (ISSBB), 1st Edition
(Naples, Itália)
2022/06/27 Extracellular vesicles in cardiovascular diseases. Extracellular Vesicles in Noncommunicable Diseases. Workshop Egas Moniz and CiiEM, Caparica, Portugal
(Costa da Caparica, Portugal)
2021/11/26 “Algas na praia”: uma iniciativa de ciência cidadã para monitorizar acumulações de algas na costa portuguesa Encontro Nacional de Ciência Cidadã 2021
Biblioteca da Universidade do Algarve, campus de Gambelas, Faro (Faro, Portugal)
2021/09/14 Unveiling the complexity of extracellular vesicles (EVs) associated with vascular calcification: Heterogeneous populations with different characteristics and features. 1st Meeting of the Portuguese Network on Extracellular Vesicles
i3S, Porto, Portugal (Porto, Portugal)
2020/12/18 The role of EVs in physiological and pathological calcification First Workshop of the Portuguese Network on Extracellular Vesicles: EVs in Health and Disease
2020/06/08 GLA-RICH PROTEIN (GRP) AS AN EARLY AND NOVEL MARKER ASSOCIATED WITH VASCULAR CALCIFICATION AND CKD-MINERAL AND BONE DISORDER (MBD) IN DIABETIC PATIENTS WITH CKD: A PILOT COHORT STUDY 57TH ERA-EDTA Congress
2019/12/03 ALGARED+: Old and new microalgae for novel bioactivities. ALGAEUROPE 2019
(Paris, França)
2019/12/03 ALGARED+: Old and new microalgae for novel bioactivities. ALGAEUROPE 2019
(Paris, França)
2019/11/18 New advances on Gla Rich Protein (GRP) as a clinical utility biomarker for cardiovascular risk assessment in chronic kidney disease Sinal 2019, 10th Meeting on signal Transduction,
(Olhão, Portugal)
2019/11/01 Amentadione, a meroditerpenoide from brown algae with capacity of modulating osteoarthritic responses, in a close-to-in-vivo OA model Joint XVI International Symposium on Marine Natural Products and XI European Conference on Marine Natural Products
(Peniche, Portugal)
2019/06/02 Nanoencapsulation as a novel delivery approach for therapeutic applications of gla-rich protein (GRP). 4th congress of CiiEM - Health, Well-Being and Ageing in the 21st Century
(Monte da Caparica, Portugal)
2019/03/28 Gla-Rich Protein: um novo marcador cardioprotector numa população de diabéticos com doença renal crónica. XXXIII Congresso Português de Nefrologia
Sociedade Portuguesa de Nefrologia (Portugal)
2019/03/26 Anti-inflammatory and dermoprotective activity of a selection of microalgae extracts. Workshop AlgaRed+, I seminário Projeto ALGARED+ Novas microalgas, novas aplicações
Universidade do Algarve (Faro, Portugal)
2018/11/03 Gla-rich Protein (GRP): A new player in the burden of vascular Calcification – clinical implications (2018) Núcleo de Biologia Vascular da SPACV
(Ílhavo, Portugal)
2018/06/21 Amentadione is a new modulating agent for osteoarthritis in an ex-vivo co-culture preclinical assay 3rd International Congress of CiiEM- Research and Innovation in Human & Health Sciences
Instituto Superior Egas Moniz (Portugal)
2018/06/20 Use of an innovative system and nanotechnology-based strategy for therapeutic applications of Gla-rich protein (GRP) 3rd International Congress of CiiEM- Research and Innovation in Human & Health Sciences,
Instituto Universitário Egas Moniz (Portugal)
2018/03/22 Gla-Rich Protein como um novo marcador de calcificações vasculares numa população de diabéticos com doença renal crónica XXXII Congresso SPN
Sociedade Portuguesa de Nefrologia (Portugal)
2017/11/05 Gla-rich Protein (GRP) is a New Therapeutic Target for Chronic Kidney Disease PCS 4th World Congress of Cardiothoracic-renal Diseases “Bridging Basic Research and Clinical Practice”
(Lisboa, Portugal)
2017/06/28 Unveiling the dual role of Gla-rich protein (GRP) in the crosstalk between inflammation and calcification in pathological processes CCMAR Seminars
(Faro, Portugal)
2017/06/12 Gla-rich protein, a vitamin K-dependent protein involved in inflammation and calcification-related diseases Translational Research and Innovation in Human and Health Sciences, 2nd International Congress of CiiEM
(Lisboa, Portugal)
2017/06/03 Circulating calciprotein particles and extracellular vesicles as novel players in chronic kidney disease vascular calcification: a role for Gla-rich protein ERA-EDTA 54th Annual Congress
Leading European Nephrology (Madrid, Espanha)
2016/07/11 Dysregulated fetuin-mineral complexes are linked to vascular calcification in chronic kidney disease: the role of Gla-rich protein Ultrapath XVII
Society for Ultrastructural Pathology (Lisboa, Portugal)
2016/04/04 In vitro testing of bioactive compounds: a bridge to clinical trials and industrial application EuroMarine Meeting entitled “Exploitation and Legal Aspects on Marine Genetic and Chemical Resources”
Institute of Protein Biochemistry, CNR Research Area (Napoles, Itália)
2016 Marine bioactive compounds: testing novel drugs for old diseases IX Xornada Cientifica Terapia Celular e medicina regenerativa
(Campus de Elviña, Espanha)
2015/07/27 New targets for therapeutics in osteoarthritis: Marine compounds and Gla rich proteins 9th SFRR-Africa/4th IAMBR conference. Translational Science and Drug Discovery: Impact on Health, Wellness, Environment and Economics
2015/06/03 Gla-rich protein (GRP) is a new player in mineralization-competence of extracellular vesicles involved in vascular calcification Joint Meeting of the European Society for Microcirculation (ESM) and European Vascular Biology Organization (EVBO)
(Pisa, Itália)
2012/11/26 Applications of Recombinant Proteins- Biomedical Perspective and Beyond. I Ciclo de Palestras, Núcleo de Estudantes de Engenharia Biológica e Biotecnologia
Universidade do Algarve (Faro, Portugal)
2012/07/11 Applications of recombinant proteins Workshop on Strategies for recombinant protein production
University of Algarve (Faro, Portugal)
2011/11/19 Papel de uma nova proteina no processo degenerativo da cartilagem articular: resultados preliminares XXXI Congresso Nacional de Ortopedia e Traumatologia
Centro de Congressos do Estoril (Estoril, Portugal)
2010/10/20 Study of Gla Rich Protein (GRP) and its potential for use as a biomarker of pathological calcification related diseases Sociedade Portuguesa de Biofísica
(Portugal)
2010/03/21 Gla Rich Protein (GRP), A New Biomarker For Ectopic Calcifications? BIT’s 3rd Annual Protein and Peptide Conference
(Beijing, China)
2010/01/29 Study of Gla Rich Protein (GRP) function in pathological calcification processes and its potential for use as a biomarker IV SPB Clinical Biochemistry Workshop
(Faro, Portugal)
2009/04/27 Fish as model organisms to uncover new Gla proteins of interest for human biology Workshop - Interdisciplinary Approaches in Fish Skeletal Biology
(Tavira, Portugal)
2009 Aplicações da análise proteomica 2D na identificação de possíveis biomarcadores para diagnóstico/prognóstico de doenças Seminário CHUAlgarve
University of Algarve (Faro, Portugal)
2008/11/12 dentification of an MGP/OC hybrid gene in Adriatic sturgeon (Acipenser naccarii), representing an ancient form of Osteocalcin CCMAR Seminars
University of Algarve (Faro, Portugal)
2008/05/08 Identification of an MGP/OC hybrid gene in the Adriatic sturgeon (Acipenser naccarii), representing an ancient form of osteocalcin. Seminários Mar e Ambiente
University of Algarve (Portugal)
2007/05/03 Identification of an MGP/OC hybrid gene in Adriatic sturgeon Acipenser naccarii Seminários Mar e Ambiente
University of Algarve (Faro, Portugal)
2005/04/21 Proteínas Gla do osso e cartilagem: importância dos anfíbios e peixes como modelos biológicos para elucidação da sua função e evolução 1º Encontro “O Mar e as Ciências da Saúde
(Caparica, Portugal)
2004/12/04 Identification of two distinct promoter regions in fish MGP genes. Implications for regulation of MGP gene expression XIV Congresso Nacional de Bioquímica
(Vilamoura, Portugal)
2004/12/02 Evolutionary relationship between bone and matrix Gla proteins XIV Congresso Nacional de Bioquímica
(Vilmaoura, Portugal)
2004/12/02 Effect of nacre extracts from the oyster Crassostrea gigas in the mineralization of bone-derived cells from Sparus aurata XIV Congresso Nacional de Bioquímica
(Vilamoura, Portugal)
2001 Detection and localization of osteocalcin (BGP or Bone Gla protein) in Teleosts by in situ hybridization and immunohistochemistry Simpósio Satélite da Sociedade Espanhola de Investigação Óssea e Metabolismo Mineral. 1st Joint Meeting of the International Bone and Mineral Society and the European Calcified Tissue Society
Sociedade Espanhola de Investigação Óssea e Metabolismo Mineral (Madrid, Espanha)

Orientação

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2023/04/01 - Atual Engineered Extracellular Vesicles (EVs) loaded with Gla-Rich Protein (GRP) as nanotherapeutics for cardiovascular and chronic kidney diseases.
Coorientador
 Programa Doutoral do Departamento de Ciências Biomédicas e de Medicina (Doutoramento)
2022/01/02 - Atual Search for novel macroalgae-derived dietary supplements with anti-inflammatory and antioxidant activity
Coorientador
 Master Thesis in Quality in Analytical Laboratories, Erasmus Mundus- Joint Program among Spain, Portugal, Poland and Norway. (Mestrado)
Universidade do Algarve - Campus de Gambelas, Portugal
2021/09/01 - Atual Marine-derived vitamin K as a natural supplement with anti-inflammatory and vascular protective properties
Coorientador
 Master thesis in Molecular and Microbial Biology (Mestrado)
Universidade do Algarve - Campus de Gambelas, Portugal
2021/04/01 - Atual Studies towards the establishment of Gla-rich protein as a biomarker for cardiovascular risk assessment
Coorientador
 Biomedical Sciences and Medicine (Doutoramento)
Universidade do Algarve - Campus de Gambelas, Portugal
2020/12/31 - Atual Studies towards the establishment of Gla-rich protein as a biomarker for cardiovascular risk assessment
Coorientador
 Ciências Biomédicas (Doutoramento)
Universidade do Algarve - Campus de Gambelas, Portugal
2024/01/15 - 2024/07/01 Exploring Algae for new anti-inflammatory and antioxidant bioactives with potential application in chronic inflammatory diseases
Coorientador
 EMBRSea Master (Mestrado)
Universiteit Gent, Bélgica
2016/01 - 2024/03 Interplay between mineralization and inflammation in vascular calcification and osteoarthritis: extracellular vesicles and marine bioactive compounds as new therapeutic approaches
Coorientador de Nuna Araújo
 Biomedical Sciences and Medicine (Doutoramento)
Universidade do Algarve - Campus de Gambelas, Portugal
2023/09/01 - 2023/12/22 Exploring Human-derived extracellular vesicles (EVs) loaded with human GRP as new anti-inflammatory nanoformulations
Orientador
 Bioquímica (Outra)
Universidade do Algarve Faculdade de Ciências e Tecnologia, Portugal
2023/09/01 - 2023/12/22 EXPLORING VITAMIN K1 AS NOVEL THERAPEUTIC PREVENTION STRATEGY FOR OSTEOARTHRITIS
Orientador
 Biologia (Outra)
Universidade do Algarve Faculdade de Ciências e Tecnologia, Portugal
2023/09/01 - 2023/12/22 Exploração do potencial de extratos de macroalgas e da Vitamina K como antioxidantes e anti-inflamatórios para novos suplementos alimentares
Orientador
 Bioquímica (Outra)
Universidade do Algarve Faculdade de Ciências e Tecnologia, Portugal
2022/09/01 - 2023/05/31 Exploring the therapeutic application of Gla-rich protein (GRP) in inflammation-related diseases using natural bioengineered nanovesicles (FlameGRP).
Orientador
Centro de Ciências do Mar, Portugal
2023/03/01 - 2023/04/30 Propriedades anti-inflamatórias de Vesiculas Extracelulares (VEs) contendo a proteína Gla Rich Protein (GRP).
Orientador
 MSc Medicine (Iniciação científica)
Universidade do Algarve Departamento de Ciências Biomédicas e Medicina, Portugal
2023/03/01 - 2023/04/30 Avaliação da atividade anti-inflamatória e antioxidante da vitamina K.
Coorientador
 MSc Medicine (Iniciação científica)
Universidade do Algarve Departamento de Ciências Biomédicas e Medicina, Portugal
2022/09/02 - 2023/01/15 Estudo do potencial anti-mineralizante e anti-inflamatório de vesiculas extracelulares contendo Gla rich Protein (GRP) em células vasculares do musculo liso.
Orientador
 Bioquímica (Outra)
Universidade do Algarve Faculdade de Ciências e Tecnologia, Portugal
2021/09/01 - 2022/09/01 Vitamin K's Importance in Osteoporosis.
Coorientador
 Mestrado em Ciências Farmacêuticas (Mestrado)
Universidade do Algarve Faculdade de Ciências e Tecnologia, Portugal
2021/09/01 - 2022/07/17 Marine-derived vitamin K as a natural supplement with anti-inflammatory and vascular protective properties.
Coorientador
 Mestrado em Biologia Molecular e Microbiana (Mestrado)
Universidade do Algarve Faculdade de Ciências e Tecnologia, Portugal
2022/03/01 - 2022/04/01 Anti-inflammatory activity of a Sargassum muticum extract containing vitamin K.
Coorientador
 MSc Medicine (Iniciação científica)
Universidade do Algarve Departamento de Ciências Biomédicas e Medicina, Portugal
2021/10/01 - 2022/03/03 Exploração de novos compostos bioativos como agentes anti-inflamatórios e anticalcificantes com potencial aplicação em doenças inflamatórias crónicas (CID)
Coorientador
 Thesis Degree in Biochemistry, University of Algarve (Outra)
Universidade do Algarve - Campus de Gambelas, Portugal
2021/07/01 - 2022/02/28 Master fellowship within the Projeto 72583 NutriSafe
Coorientador
 Project fellowship (Outra)
Universidade do Algarve - Campus de Gambelas, Portugal
2021/09/20 - 2022/02/18 Enzyme-Linked Immunosorbent Assay (ELISA) for detection and quantification of specific proteins
Orientador
 Subject “Lab&Field Methods”, Master in Molecular and Microbial Biology (Outra)
Universidade do Algarve - Campus de Gambelas, Portugal
2021/10/01 - 2022/01/31 Preventive and therapeutic anti-inflammatory effect of Vitamin K1 and MK-4 in LPS induced THP-1 macrophages
Coorientador
 Subject “Projeto”, Master Pharmaceutical Sciences, UALG-FCT (Outra)
Universidade do Algarve - Campus de Gambelas, Portugal
2021/06/01 - 2021/07/31 Purification and characterization of human Gla rich protein (GRP) overexpressed in the E. Coli system
Coorientador
 Internship, Master in Molecular and Microbial Biology, UALG (Outra)
Universidade do Algarve - Campus de Gambelas, Portugal
2021/02/01 - 2021/07/29 Methods for the study of Gla-rich protein (GRP) in vascular calcification and inflammation
Coorientador
 Bachelor thesis in Biology, Internship student of Biology, University of Aveiro (Outra)
Universidade do Algarve - Campus de Gambelas, Portugal
2021/01/18 - 2021/02/22 Anti-inflammatory potential of microalgae-derived bioactive extracts for skin application
Orientador
 MSc Medicine (Iniciação científica)
Universidade do Algarve - Campus de Gambelas, Portugal
2018 - 2020/09 Preclinical studies for development and testing of dermocosmetics from marine origin
Coorientador
 MSc Pharmaceutical Sciences (Mestrado)
Universidade do Algarve - Campus de Gambelas, Portugal
2018/09/01 - 2019/09/15 Searching for innovative antitumoral drugs in marine microalgae
Orientador
 Analytical Laboratories (Mestrado)
Universidade do Algarve - Campus de Gambelas, Portugal
2018/09/01 - 2019/09/15 Extraction of anti-inflammatory drugs form Microalgae
Orientador
 Analytical Laboratories (Mestrado)
Universidade do Algarve - Campus de Gambelas, Portugal
2019 - 2019 Gla-rich protein, a marker for calcification propensity in diabetic with chronic kidney disease
Coorientador
 MSc Medicine (Iniciação científica)
Universidade do Algarve - Campus de Gambelas, Portugal
2019 - 2019 Testing the therapeutic potential of Gla Rich Protein-chitosan-tripolyphosphate nanoparticles for osteoarthritis using an ex-vivo co-culture preclinical assay
Coorientador
 MSc Medicine (Iniciação científica)
Universidade do Algarve - Campus de Gambelas, Portugal
2018/03/01 - 2018/09/30 Extracellular vesicles in cardiovascular therapeutics
Orientador
 Erasmus+ Learning agreement student mobility traineeship (Iniciação científica)
Universidade do Algarve - Campus de Gambelas, Portugal
2018 - 2018 Study the role of GRP produced by inflammatory cells in mediating VSMCs inflammation
Orientador
 Biomedical Sciences and Medicine (Iniciação científica)
Universidade do Algarve - Campus de Gambelas, Portugal
2018 - 2018 Study the association of Gla-rich protein (GRP) with urinary extracellular vesicles (EVs) and chronic kidney disease (CKD)
Orientador
 MSc Medicine (Iniciação científica)
Universidade do Algarve - Campus de Gambelas, Portugal
2018 - 2018 Testing the anti-inflammatory potential of Gla Rich Protein nanoparticles for its use in therapeutics
Orientador
 MSc Medicine (Iniciação científica)
Universidade do Algarve - Campus de Gambelas, Portugal
2014/01 - 2017/12 Studies towards unveiling the association of Gla-rich protein with osteoarthritis
Coorientador
 Biological Sciences (Doutoramento)
Universidade do Algarve - Campus de Gambelas, Portugal
2017/03/01 - 2017/03 Como podem as proteínas dizer-nos se estamos doentes?
Orientador
Universidade do Algarve - Campus de Gambelas, Portugal
2017 - 2017 In vitro studies to determine the role of fetuin-mineral complex in the calcification stress in CKD
Orientador
 MSc Medicine (Iniciação científica)
Universidade do Algarve - Campus de Gambelas, Portugal
2017 - 2017 Can we use the tissues obtained from OA patients to set up a 3D in vitro model for the study of osteoarthritis?
Orientador
 MSc Medicine (Iniciação científica)
Universidade do Algarve - Campus de Gambelas, Portugal
2016 - 2017 Clinical application of Extracellular Vesicles in Cardiovascular Diseases
Coorientador
 MSc Pharmaceutical Sciences (Mestrado)
Universidade do Algarve - Campus de Gambelas, Portugal
2016 - 2017 Bioactive marine compounds as novel therapeutics in osteoarthritis
Coorientador
 MSc Biomedical Sciences (Mestrado)
Universidade do Algarve - Campus de Gambelas, Portugal
2015 - 2016 Studies towards the use of extracellular vesicles as novel biomarkers for vascular calcification
Coorientador
 MSc Molecular Genetics and Biomedicine (Mestrado)
Universidade do Algarve - Campus de Gambelas, Portugal
2014 - 2015 Cultivation techniques of THP-1 cell line, isolation of extracellular vesicles and characterization of its components
Coorientador
 Biology (Licenciatura/Bacharelato)
Universidade do Algarve - Campus de Gambelas, Portugal
2014 - 2015 Gla-Rich-Protein (GRP): a Novel Vitamin K-Dependent Protein, with potential to interfere with the dynamics of basic-calcium phosphate (BCP) crystals formation
Coorientador
 Biochemistry (Licenciatura/Bacharelato)
Universidade do Algarve - Campus de Gambelas, Portugal
2014 - 2014 Calcified aortic valve and aortic rings: what’s the role of Gla-rich protein?
Orientador
 MSc Medicine (Iniciação científica)
Universidade do Algarve - Campus de Gambelas, Portugal
2013 - 2013 GRP gene expression in different mouse tissues
Coorientador
 MSc Marine Biodiversity and Conservation (Mestrado)
Universidade do Algarve - Campus de Gambelas, Portugal
2012 - 2013 Study of the association of Gla-rich protein (GRP/UCMA) to human blood cells
Coorientador
 MSc Biomedical Sciences (Mestrado)
Universidade do Algarve - Campus de Gambelas, Portugal
2011 - 2011 Estudo e caracterização da interacção da proteína GRP recombinante humana com o cálcio
Coorientador
 Biology (Iniciação científica)
Universidade do Algarve - Campus de Gambelas, Portugal
2011 - 2011 Estudo e caracterização da interacção da proteína GRP nativa com o cálcio
Coorientador
 Biology (Iniciação científica)
Universidade do Algarve - Campus de Gambelas, Portugal
2010 - 2011 Produção e purificação da proteína GRP humana recombinante não gama-carboxilada
Coorientador
 MSc Molecular Biology and Microbiology (Mestrado)
Universidade do Algarve - Campus de Gambelas, Portugal
2009 - 2010 Estudo da relação entre as proteínas contendo Gla e os tumores
Coorientador
 Biomedical Sciences (Licenciatura/Bacharelato)
Universidade do Algarve - Campus de Gambelas, Portugal
2009 - 2010 Detecção das Proteínas Gla no osso de Xenopus laevis
Coorientador
 Biochemistry (Licenciatura/Bacharelato)
Universidade do Algarve - Campus de Gambelas, Portugal
2009 - 2010 Detecção das Proteínas Gla com capacidade de ligar ao mineral de hidroxiapatite no coração de Gallus gallus domesticus (Galinha)
Coorientador
 Biochemistry (Licenciatura/Bacharelato)
Universidade do Algarve - Campus de Gambelas, Portugal
2008 - 2009 Estudo das proteínas contendo Gla, dependentes da vitamina K, associadas a patologias calcificantes na pele
Coorientador
 Biomedical Sciences (Licenciatura/Bacharelato)
Universidade do Algarve - Campus de Gambelas, Portugal
2007 - 2008 Clonagem e distribuição tecidular de marcadores moleculares de osso e cartilagem do esturjão, Acipencer naccarii
Coorientador
 Biochemistry (Licenciatura/Bacharelato)
Universidade do Algarve - Campus de Gambelas, Portugal

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação) 		Instituição / Organização
2023/07/14 - Atual Member of the organizing committee of Nutrisafe Workshop - Valorisation of invasive seaweed biomass to develop new products for the blue bioeconomy, 14th July 2023, University of Algarve, Faro, Portugal. (2023/07/14)
Oficina (workshop) (Coorganizador)
 Universidade do Algarve Faculdade de Ciências e Tecnologia, Portugal
2025/06/26 - 2025/06/27 Organization of the 3rd Portuguese Network on Extracellular Vesicles Association (PNEV) Meeting (2025/06/26 - 2025/06/27)
Congresso
 Portuguese Network on Extracellular Vesicles Association, Portugal
2022/05/11 - 2022/05/13 Organization of the ProteoVilamoura, 2nd Joint Meeting of Spanish, French and Portuguese Proteomics Societies (2022/05/11 - 2022/05/13)
Congresso (Coorganizador)
2022/05/11 - 2022/05/13 Scientific Committee of ProteoVilamoura, 2nd Joint Meeting of Spanish, French and Portuguese Proteomics Societies (2022/05/11 - 2022/05/13)
Congresso (Membro da Comissão Científica)
2015/12/15 - 2015/12/15 New, High Throughput Tools and Methods for Label-Free Characterization of Biotherapeutic Molecules. Invited speaker Attila Aranyos, PhD Sales Manager Western Europe, Pall Life Sciences – FortéBio, 2015 Seminar at CCMAR-UALG (2015/12/15 - 2015/12/15)
Seminário (Membro da Comissão Organizadora)
 Universidade do Algarve - Campus de Gambelas, Portugal
2015/12/02 - 2015/12/02 Nanoparticles characterization by NTA-Nanoparticle tracking analysis; concepts and applications by Paralab 2015 Seminar at CCMAR-UALG (2015/12/02 - 2015/12/02)
Seminário (Membro da Comissão Organizadora)
 Universidade do Algarve - Campus de Gambelas, Portugal
2015/09/21 - 2015/09/25 Biomedical and biological applications of scanning and transmission electron microscopy (2015/09/21 - 2015/09/25)
Oficina (workshop) (Membro da Comissão Organizadora)
 Universidade do Algarve - Campus de Gambelas, Portugal
2015/07/01 - 2015/07/03 Three days Proteomics course on 2D-electrophoresis techniques - From 2DE to protein identification by mass spectrometry (2015/07/01 - 2015/07/03)
Oficina (workshop) (Membro da Comissão Organizadora)
 Universidade do Algarve - Campus de Gambelas, Portugal
2014/07/02 - 2014/07/04 Three-day proteomics course on 2D-electrophoresis techniques “From 2DE to protein identification by mass spectrometry (2014/07/02 - 2014/07/04)
Oficina (workshop)
 Universidade do Algarve - Campus de Gambelas, Portugal
2012/07/11 - 2012/07/12 Workshop on Strategies for recombinant protein production (2012/07/11 - 2012/07/12)
Oficina (workshop) (Membro da Comissão Organizadora)
 Universidade do Algarve - Campus de Gambelas, Portugal
2012/07/04 - 2012/07/06 Three-day proteomics course on 2D-electrophoresis techniques - From 2DE to protein identification by mass spectrometry (2012/07/04 - 2012/07/06)
Oficina (workshop) (Membro da Comissão Organizadora)
 Universidade do Algarve - Campus de Gambelas, Portugal
2011/07/13 - 2011/07/15 Three-day course on Strategies for recombinant protein production (2011/07/13 - 2011/07/15)
Oficina (workshop) (Membro da Comissão Organizadora)
 Universidade do Algarve - Campus de Gambelas, Portugal
2011/07/06 - 2011/07/08 Three-day proteomics course on 2D-electrophoresis techniques - From 2DE to protein identification by mass spectrometry (2011/07/06 - 2011/07/08)
Oficina (workshop) (Membro da Comissão Organizadora)
 Universidade do Algarve - Campus de Gambelas, Portugal

Participação em evento

Descrição da atividade
Tipo de evento 		Nome do evento
Instituição / Organização
2020/02/20 - Atual Dia Aberto UAlg Dia Aberto UAlg
Universidade do Algarve, Portugal
2019/02/21 - Atual Dia Aberto UAlg
Universidade do Algarve, Portugal
2018/10/13 - Atual Núcleo de Biologia Vascular da SPACV
Encontro
 Núcleo de Biologia Vascular da SPACV
2022/12/06 - 2022/12/07 International Conference Aging without Borders- Oral Communication
Conferência
 International Conference Aging without Borders
2022/06/27 - 2022/06/27 Workshop Egas Moniz and CiiEM, Caparica, Portugal- oral communication
Oficina (workshop)
 Workshop Egas Moniz and CiiEM, Caparica, Portugal
2022/05/11 - 2022/05/13 ProteoVilamoura, 2nd Joint Meeting of Spanish, French and Portuguese Proteomics Societies
Congresso
 ProteoVilamoura, 2nd Joint Meeting of Spanish, French and Portuguese Proteomics Societies
2021/09/13 - 2021/09/14 First Meeting of the Portuguese Network on Extracellular Vesicles- Oral communication
Conferência
 First Meeting of the Portuguese Network on Extracellular Vesicles
2021/08/30 - 2021/09/01 XII European Conference on Marine Natural Products- Poster communication
Congresso
 XII European Conference on Marine Natural Products
2021/06/01 - 2021/06/02 1º Congresso da Rede de Instituições do Ensino Superior para a Salvaguarda da Dieta Mediterrânica
Conferência
 1º Congresso da Rede de Instituições do Ensino Superior para a Salvaguarda da Dieta Mediterrânica
2020/12/18 - 2020/12/18 First Workshop of the Portuguese Network on Extracellular Vesicles: EVs in Health and Disease
Oficina (workshop)
 First Workshop of the Portuguese Network on Extracellular Vesicles: EVs in Health and Disease
2020/06/06 - 2020/06/09 57TH ERA-EDTA Fully Virtual Congress
Congresso
 57TH ERA-EDTA Congress
2019/07/01 - 2019/07/05 Cursos de Verão UAlg Cursos de Verão UAlg
Universidade do Algarve, Portugal
2018/07/15 - 2018/08/05 FUNCTIONAL BIOCHEMISTRY AND PROTEOMICS Research team hosted 2 students during Summer School Programme - SHOU University at the Centre for Marine Sciences - University of Algarve, from 15th of July and 05th of August 2018
Outro
 Summer School SHOU, 2018
Universidade do Algarve - Campus de Gambelas, Portugal
2018/06/20 - 2018/06/22 3rd International Congress of CiiEM- Research and Innovation in Human & Health Sciences
Congresso
 3rd International Congress of CiiEM- Research and Innovation in Human & Health Sciences
2017/09/07 - 2017/09/08 Gla-rich protein (GRP) as a novel biomarker of vascular calcification stress in chronic kidney disease (CKD). Oceans Meeting 2017- CCMAR, A hub of science, innovation & training for the blue economy
Simpósio
 Brochure GenoGla Diagnostics
Universidade do Algarve - Campus de Gambelas, Portugal
2017/07/09 - 2017/08/01 FUNCTIONAL BIOCHEMISTRY AND PROTEOMICS Research team hosted 4 students during Summer School Programme - SHOU University at the Centre for Marine Sciences - University of Algarve, from 09th of July and 01st of August 2017.
Outro
 Summer School SHOU, 2017
Universidade do Algarve - Campus de Gambelas, Portugal
2017/06/03 - 2017/06/06 ERA-EDTA 54th Annual Congress
Congresso
 ERA-EDTA 54th Annual Congress
2016/07/11 - 2016/07/15 Ultrapath XVII, Society for Ultrastructural Pathology
Congresso
 Ultrapath XVII, Society for Ultrastructural Pathology
2015/06/03 - 2015/06/06 Joint Meeting of the European Society for Microcirculation (ESM) and European Vascular Biology Organization (EVBO)
Congresso
 Joint Meeting of the European Society for Microcirculation (ESM) and European Vascular Biology Organization (EVBO)
2011/06/26 - 2011/07/01 FASEB Summer Research Conferences on Molecular, Structural & Clinical Aspects of Vitamin K & Vitamin K Dependent Proteins
Conferência
 FASEB Summer Research Conferences on Molecular, Structural & Clinical Aspects of Vitamin K & Vitamin K Dependent Proteins
2010/03/21 - 2010/03/23 BIT’s 3rd Annual Protein and Peptide Conference
Conferência
 BIT’s 3rd Annual Protein and Peptide Conference
2008/05/24 - 2008/05/28 35th ECTS Meeting
Congresso
 35th ECTS Meeting
2004/12/02 - 2004/12/04 XIV Congresso Nacional de Bioquímica
Congresso
 XIV Congresso Nacional de Bioquímica
2000/09/28 - 2000/09/30 XII Congresso Nacional de Bioquímica
Congresso
 XII Congresso Nacional de Bioquímica

Júri de grau académico

Tema
Tipo de participação 		Nome do candidato (Tipo de grau)
Instituição / Organização
2023/12/05 Bioprospeção de compostos naturais de microalgas para o tratamento da doença inflamatória do instestino
Arguente principal
 MARIANA ALVES (Mestrado)
Universidade do Algarve Faculdade de Ciências e Tecnologia, Portugal
2023/11/01 Estudo do potencial anti-mineralizante e anti-inflamatório de vesiculas extracelulares contendo Gla rich Protein (GRP) em células vasculares do musculo liso
Arguente
 André Bagão (Outro)
Universidade do Algarve Faculdade de Ciências e Tecnologia, Portugal
2023/09/22 SEARCHING FOR BIOACTIVE COMPOUNDS IN THE MICROALGAE NANOFRUSTULUM SHILOI.
Arguente principal
 UGONNA NWANKPA (Mestrado)
2023/09/22 ISOLATION AND IDENTIFICATION OF BIOACTIVE COMPOUNDS FROM MICROALGAE.
Arguente principal
 SEGISMUNDO VALVERDE (Mestrado)
2022/12/12 Vitamin K's Importance in Osteoporosis
Arguente
 Nicoleta Cristafovici (Mestrado)
Universidade do Algarve Faculdade de Ciências e Tecnologia, Portugal
2018 Prospection of bioactivities, bioaccessibility, and biochemical characterization of green seaweeds grown in integrated multi-trophic aquaculture environments
Arguente
 Andrea Ripol Malo (Mestrado)
Universidade do Algarve - Campus de Gambelas, Portugal
2017 Clinical application of extracellular vesicles in Cardiovascular Disease
Orientador
 Catarina Marreiros (Mestrado)
Universidade do Algarve - Campus de Gambelas, Portugal
2017 Studies towards unveiling the association of Gla-rich protein with osteoarthritis
Orientador
 Sofia Cavaco (Doutoramento)
Universidade do Algarve - Campus de Gambelas, Portugal
2013 Study of the association of Gla-rich protein (GRP/UCMA) to human blood cells
Orientador
 Rúben Costa (Mestrado)
Universidade do Algarve - Campus de Gambelas, Portugal
2011 Produção e purificação da proteína GRP humana recombinante não gama-carboxilada
Orientador
 Vera Maria (Mestrado)
Universidade do Algarve - Campus de Gambelas, Portugal
2010 Detecção das Proteínas Gla com capacidade de ligar ao mineral de hidroxiapatite no coração de Gallus gallus domesticus (Galinha)
Orientador
 Miguel de Sousa Viegas (Outro)
Universidade do Algarve - Campus de Gambelas, Portugal
2008 Clonagem e distribuição tecidular de marcadores moleculares de osso e cartilagem do esturjão, Acipencer naccarii
Orientador
 Paulo Dias (Outro)
Universidade do Algarve - Campus de Gambelas, Portugal

Arbitragem científica em revista

Nome da revista (ISSN) Editora
2024/12/05 - 2024/12/19 Arteriosclerosis, Thrombosis, and Vascular Biology American Heart Association
2024/10/01 - 2024/10/30 Scientific Reports Springer Nature
2024/03/01 - 2024/03/26 Cells MDPI
2023/07/20 - 2023/10/23 CARDIOVASCULAR DIABETOLOGY Springer
2023/08/28 - 2023/09/11 BIOMEDICINE & PHARMACOTHERAPY Elsevier
2023/01/01 - 2023/02/01 BMC Cardiovascular Diseases Springer
2021/02/01 - 2021/03/04 Renal Failure Taylor&Francis
2021 - 2021 International Journal of Molecular Sciences (IJMS) (1422-0067) MDPI
2020 - 2020 Nutrients (2072-6643) MDPI
2016 - 2016 BioMed Research International (2314-6141) Hindawi
2016 - 2016 Open Chemistry (2391-5420) De Gruyter Open Access

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2024/09/01 - 2025/01/31 Bioquímica Geral Bioquímica Geral (Licenciatura) Universidade do Algarve Faculdade de Ciências e Tecnologia, Portugal
2023/03/11 - 2023/05/29 Recursos Biológicos Marinhos Biologia Marinha (Licenciatura) Universidade do Algarve Faculdade de Ciências e Tecnologia, Portugal
2022/10/11 - 2022/11/23 Bioquímica Geral Biologia Marinha (Licenciatura) Universidade do Algarve Faculdade de Ciências e Tecnologia, Portugal
2022/10/11 - 2022/11/23 Bioquímica Geral Biologia (Licenciatura) Universidade do Algarve Faculdade de Ciências e Tecnologia, Portugal
2022/10/11 - 2022/11/23 Bioquímica Geral Bioengenharia (Licenciatura) Universidade do Algarve Faculdade de Ciências e Tecnologia, Portugal
2022/07/08 - 2022/07/08 Cursos de Verão UAlg: À Descoberta da Cultura Celular Universidade do Algarve Faculdade de Ciências e Tecnologia, Portugal
2022/07/05 - 2022/07/05 MBRSea- Annual Simposium- How a citizen science algae project can help discover marine bioactive compounds as¿novel medicines and how do we test their therapeutic potential IMBRSea (Mestrado) Universidade do Algarve Faculdade de Ciências e Tecnologia, Portugal
2022/07/05 - 2022/07/05 IMBRSea- Annual Simposium- Marine bioactive compounds as¿novel medicines to treat chronic inflammation related diseases. IMBRSea (Mestrado) Universidade do Algarve Faculdade de Ciências e Tecnologia, Portugal
2022/03/04 - 2022/05/29 Recursos Biológicos Marinhos Biologia Marinha (Licenciatura) Universidade do Algarve Faculdade de Ciências e Tecnologia, Portugal
2022/05/03 - 2022/05/04 Dia Aberto Ualg: Cultura Celular: Aventura no Multiverso da Ciência Universidade do Algarve Faculdade de Ciências e Tecnologia, Portugal
2022/01/04 - 2022/01/04 Seminário Biotecnologia Azul- Prospecting the sea for marine bioactive compounds to discover novel medicines to treat chronic inflammation in Osteoarthritis Gestão Marinha e Costeira (Doutoramento) Universidade do Algarve Faculdade de Ciências e Tecnologia, Portugal
2021/10/18 - 2021/11/29 Bioquímica Geral Biologia Marinha (Licenciatura) Universidade do Algarve Faculdade de Ciências e Tecnologia, Portugal
2021/10/18 - 2021/11/20 Bioquimica Geral Biologia (Licenciatura) Universidade do Algarve Faculdade de Ciências e Tecnologia, Portugal
2021/07/26 - 2021/07/30 Estágios de Verão Ciência Viva 2021: Qual a relação entre a calcificação e a inflamação nos nossos vasos sanguíneos e como isto pode afetar a nossa saúde? Centro de Ciências do Mar, Portugal
2021/03/03 - 2021/05/26 Recursos Biológicos Marinhos Biologia Marinha (Licenciatura) Universidade do Algarve Faculdade de Ciências e Tecnologia, Portugal
2021/01/15 - 2021/01/15 Seminário Biotecnologia Azul: Bioactive compounds obtained from marine resources open novel avenues for¿osteoarthritis therapeutics Gestão Marinha e Costeira (Licenciatura) Universidade do Algarve Faculdade de Ciências e Tecnologia, Portugal
2020/11/17 - 2020/12/17 Bioquímica Geral Biologia (Licenciatura) Universidade do Algarve Faculdade de Ciências e Tecnologia, Portugal
2020/10/27 - 2020/11/17 Bioquímica Geral Biologia Marinha (Licenciatura) Universidade do Algarve Faculdade de Ciências e Tecnologia, Portugal
2020/07/15 - 2020/08/03 Estágios de Verão Ciência Viva 2020: Novos anti-inflamatórios de origem marinha para aplicação terapêutica e cosmética. Centro de Ciências do Mar, Portugal
2020/03/05 - 2020/03/05 Projeto Cientificamente provável: Do tubo de ensaio ao consultório médico: a importância de biomarcadores no diagnóstico e tratamento de doenças.
2020/02/20 - 2020/02/20 Dia Aberto Ualg: Vamos encontrar novos fármacos e cosméticos de origem marinha para tratar doenças e travar o envelhecimento! Universidade do Algarve Faculdade de Ciências e Tecnologia, Portugal
2019/09/15 - 2019/11/04 Bioquímica Geral Biologia (Licenciatura) Universidade do Algarve Faculdade de Ciências e Tecnologia, Portugal
2019/09/15 - 2019/11/04 Bioquímica Geral Biologia Marinha (Licenciatura) Universidade do Algarve Faculdade de Ciências e Tecnologia, Portugal
2019/09/26 - 2019/09/26 Seminário Biotecnologia Azul: Treating¿old¿diseases¿with¿new¿bioactive¿compounds¿obtained¿from¿marine¿resources Gestão Marinha e Costeira (Licenciatura) Universidade do Algarve Faculdade de Ciências e Tecnologia, Portugal
2019/07/01 - 2019/07/05 Cursos de Verão UAlg: Cosméticos e fármacos que encontramos no Mar! Universidade do Algarve Faculdade de Ciências e Tecnologia, Portugal
2019/02/21 - 2019/02/21 Dia Aberto Ualg: Vamos encontrar novos fármacos e cosméticos de origem marinha para tratar doenças e travar o envelhecimento! Universidade do Algarve Faculdade de Ciências e Tecnologia, Portugal
2018/07/15 - 2018/08/05 Summer School SHOU: Bioactivity of marine compounds. Centro de Ciências do Mar, Portugal
2017/09/01 - 2018/02/28 Techniques in Molecular and Cellular Biology (Mestrado) Universidade do Algarve Faculdade de Ciências e Tecnologia, Portugal
2017/07/09 - 2017/08/01 Summer School SHOU: Testing marine bioproducts as potential¿novel cosmetics. Centro de Ciências do Mar, Portugal
2017/07/01 - 2017/07/15 5ª Edição Mitose: Ciência a Sul: Como podem as proteínas dizer-nos se estamos doentes? Universidade do Algarve Faculdade de Ciências e Tecnologia, Portugal
2016/07/12 - 2016/07/12 Summer Courses - "Vamos tornar as células humanas fluorescentes!" (Ensino secundário) Universidade do Algarve - Campus de Gambelas, Portugal
2015/07/06 - 2015/07/17 Scientific Occupation for Young People in Summer (Outros) Universidade do Algarve - Campus de Gambelas, Portugal
2015/07/07 - 2015/07/07 Summer Courses 2015- Como se faz o diagnóstico de doenças no laboratório (Outros) Universidade do Algarve - Campus de Gambelas, Portugal
2015/06/30 - 2015/06/30 Summer Courses 2015 - "Vamos tornar as células humanas fluorescentes!” (Outros) Universidade do Algarve - Campus de Gambelas, Portugal
2015/04/30 - 2015/04/30 Highschool Vila Real de Santo António Open Day- "Como pode a histologia ajudar os médicos no diagnóstico?" (Outros) Universidade do Algarve - Campus de Gambelas, Portugal
2015/02/26 - 2015/02/26 University of Algarve Open Day - "Como pode a histologia ajudar os médicos no diagnóstico" (Outros) Universidade do Algarve - Campus de Gambelas, Portugal
2014/11/24 - 2014/11/24 Lecture at Principal School D. Martinho Castelo Branco- "Do tubo de ensaio ao consultório médico: a importância de biomarcadores no diagnóstico e tratamento de doenças " (Ensino básico 2º ciclo) Universidade do Algarve - Campus de Gambelas, Portugal
2013/12/11 - 2013/12/12 2ª Edition of Mitose: Ciência a Sul, 2013 - "Histologia: análise de tecidos” (Ensino secundário) Universidade do Algarve - Campus de Gambelas, Portugal

Membro de associação

Nome da associação Tipo de participação
2024/11/01 - Atual Portuguese Network on Extracellular Vesicles Association (PNEV) Member of the Fiscal Board
2022/04/01 - Atual Procura OMICS Member
2020/04/01 - Atual European Renal Association (ERA) Member
2008/02/01 - Atual European Calcified Tissue Society (ECTS) Member
2000/02/01 - Atual Portuguese Biochemical Society (SPB) Member

Outro júri / avaliação

Descrição da atividade Instituição / Organização
2022/09/01 - 2022/11/01 External evaluator of 2 research projects Egas Moniz funding program “Egas Moniz/ CiiEM investiga
2015 - 2015 Project Fellowship Supervision CCMAR/BI/0018/2015 (2015) under the frame of project PTDC/BIM-MECI1168/2012- Araújo, Nuna PhD- 3 months Universidade do Algarve - Campus de Gambelas, Portugal
2015 - 2015 Project Fellowship Supervision CCMAR/BI/0005/2015 (2015) under the frame of project PTDC/SAU-ORG/117266/2010- Araújo, Nuna PhD- 4 months Universidade do Algarve - Campus de Gambelas, Portugal
2014 - 2015 Project Fellowship Supervision CMAR/BI/0019/2014 (2014-2015) under the frame of project PTDC/SAU-ORG/117266/2010- Costa, Rúben MSc – 10 months Universidade do Algarve - Campus de Gambelas, Portugal
2014 - 2015 Project Fellowship Supervision CCMAR/BI/0020/2014 (2015) under the frame of project PTDC/BIM-MECI1168/2012- Santos, Lúcia MSc - 12 months Universidade do Algarve - Campus de Gambelas, Portugal
2013 - 2014 Project Fellowship Supervision under the frame of project PTDC/BIM-MECI1168/2012- Luis, Ines, MSc – 5 months; Universidade do Algarve - Campus de Gambelas, Portugal
2013 - 2014 Project Fellowship Supervision under the frame of project PTDC/SAU-ORG/117266/2010- Santos, Sofia MSc - 13 months Universidade do Algarve - Campus de Gambelas, Portugal
2013 - 2014 Project Fellowship Supervision under the frame of project PTDC/SAU-ORG/112832/2009- Costa, Rúben MSc – 9 months Universidade do Algarve - Campus de Gambelas, Portugal
2013 - 2013 Project fellowship supervision under the frame of project PTDC/SAU-ORG/112832/2009- Luis, Ines, MSc - 6 months Universidade do Algarve - Campus de Gambelas, Portugal
Distinções

Prémio

2024 BInov
Secção Regional do Sul e Regiões Autónomas da Ordem dos Farmacêuticos, Portugal
2023 BEST ABSTRACT SUBMITTED IN PERITONEAL DIALYSIS AREA
Sociedade Portuguesa de Nefrologia, Portugal
2020 Prize Roche- Teresa Azevedo/SPN
Sociedade Portuguesa de Nefrologia, Portugal
2019 Best oral communication XVI MANAPRO & XI ECMNP
Universidade do Algarve - Campus de Gambelas, Portugal
2019 2019/Prize Fresenius/SPN
Sociedade Portuguesa de Nefrologia, Portugal
2019 2019, Prize Funding of Research project/ SPN
Sociedade Portuguesa de Nefrologia, Portugal
2018 Best communication in “Nefrologia de Ligação”
2018 Prize Best oral communication in “Nefrologia de Ligação”/Encontro Renal 2018-SPN-Sociedade Portuguesa de Nefrologia
Sociedade Portuguesa de Nefrologia, Portugal
2017 Prémio Roche - Teresa Azevedo
Sociedade Portuguesa de Nefrologia, Portugal
2017 Prize Funding of Research project /SPN- Sociedade Portuguesa de Nefrologia
Sociedade Portuguesa de Nefrologia, Portugal
2017 Prize Roche- Teresa Azevedo/SPN- Sociedade Portuguesa de Nefrologia
Sociedade Portuguesa de Nefrologia, Portugal
2010 Prémio Fresenius 2010
Sociedade Portuguesa de Nefrologia, Portugal
2009 Premio Empreender-Apresentação de ideias e negócios
2001 Prémio George F. Papenfuss - Melhor Poster
2000 Melhores 20 Posters