???global.info.a_carregar???
Eduardo Jorge Sousa da Rocha was born in Luanda, Angola, and holds Portuguese nationality. He is a Full Professor at ICBAS – School of Medicine and Biomedical Sciences, University of Porto, and a Principal Researcher at the Interdisciplinary Centre of Marine and Environmental Research (CIIMAR), where he was a founding member and served on the Board of Directors and as President of the General Assembly. He graduated in Aquatic Sciences with a final grade of 18/20, as best student (Eng. António Almeida Foundation Prize, awarded by the President of Portugal), and studied Medicine for three years before completing a PhD (2001) and a Habilitation (Agregação, 2007) in Biomedical Sciences. At ICBAS, he directs the Microscopy Department and the Histology and Embryology Laboratory, serves as Local Mobility Coordinator, and is a member of the Scientific Council. At CIIMAR, he leads the Animal Morphology and Toxicology (AMTOX) group. His research consistently bridges environmental health and biomedicine, focusing on the mechanisms of endocrine and metabolic disruptors (EDCs, PPAR ligands, PAHs, pesticides) in fish liver and gonads. As a recognized expert in quantitative microscopy and image analysis, he has pioneered the application of rigorous stereological and morphometric methods to evaluate toxicopathic lesions and cellular responses. By using in vivo and in vitro New Approach Methodologies (including 3D liver NAMs) under global warming scenarios, he continues to reinforce the translational and public health dimension of his work, including studies on how environmental contaminants interfere with anti-cancer drug efficacy. He has authored more than 255 international publications, including 240 documents indexed in Scopus (including 9 book chapters), achieving an H-index of 42 (Scopus), reflecting sustained productivity and international impact. He has extensive experience in advanced training, having directed the PhD programme in Biomedical Sciences (ca. 175 enrolled students) and the MSc in Marine Sciences – Marine Resources (ca. 40 enrolled students). His mentorship record includes 15 completed PhD theses (plus 5 ongoing), 45 MSc dissertations, and 8 post-doctoral projects. He has been PI or Co-PI in 4 projects and a team member in 18 competitively funded projects, and serves on the Editorial Board of 9 international journals indexed in SCOPUS/WOS. This long-term, coherent track record in fish liver toxicology, high-end quantitative microscopy, and the development of NAMs, coupled with robust supervision and high-level academic management, provides a solid and competitive basis for leading innovative research and supervising PhD projects at the interface of aquatic and human health.
Ler resumo completo ↓
Identificação

Identificação pessoal

Nome completo
Eduardo Jorge Sousa da Rocha

Nomes de citação

  • Rocha, Eduardo

Identificadores de autor

Ciência ID
A818-5B6C-2D03
ORCID iD
0000-0001-9813-4389

Websites

Domínios de atuação

  • Ciências Médicas e da Saúde - Medicina Básica - Anatomia e Morfologia
  • Ciências Médicas e da Saúde - Medicina Básica - Toxicologia
  • Ciências Naturais - Ciências da Terra e do Ambiente - Recursos Aquáticos
  • Ciências Naturais - Ciências Biológicas - Biologia Marinha

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador proficiente (C1) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2)
Formação
Grau Classificação
2007
Concluído
 Agregação | Habilitation (Título de Agregado)
ICBAS - U.Porto, Portugal
 Unanimously Approved
2001
Concluído
 Ciências Biomédicas | Biomedical Sciences (Doutoramento)
ICBAS - U.Porto, Portugal
"Microscopic Morphology of the Brown Trout Liver: A Qualitative and Quantitative Study" (TESE/DISSERTAÇÃO)
 Unanimously Approved
1995
Concluído
 Aptidão Pedagógica e Capacidade Científica | Pedagogical Aptitude and Scientific Capacity (Outros)
ICBAS - U.Porto, Portugal
 Unanimously Approved
1990
Concluído
 Ciências do Meio Aquático | Aquatic Sciences (Licenciatura)
ICBAS - U.Porto, Portugal
 18
Percurso profissional

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento		 Empregador
2008 - Atual Professor Catedrático (Docente Universitário) ICBAS - U.Porto, Portugal

Cargos e Funções

Categoria Profissional
Instituição de acolhimento		 Empregador
2010 - Atual Director of the Master in Marine Sciences - Marien Resources Universidade do Porto - Instituto de Ciências Biomédicas de Abel Salazar, Portugal
2010 - Atual Director of the Doctoral Program in Biomedical Sciences Universidade do Porto - Instituto de Ciências Biomédicas de Abel Salazar, Portugal
2001 - Atual Member of the Scientific Council Universidade do Porto - Instituto de Ciências Biomédicas de Abel Salazar, Portugal
2002 - 2010 Presidente do Conselho Pedagógico Universidade do Porto - Instituto de Ciências Biomédicas de Abel Salazar, Portugal

Outros

Categoria Profissional
Instituição de acolhimento		 Empregador
2009 - Atual Diretor of the Lab. of Histology and Embryology Universidade do Porto - Instituto de Ciências Biomédicas de Abel Salazar, Portugal
2009 - Atual Coordenador Local de Mobilidade (Local Mobility Coordinator) Universidade do Porto - Instituto de Ciências Biomédicas de Abel Salazar, Portugal
2008 - Atual Principal Researcher of the Group of Animal Morphology and Toxicology Interdisciplinary Center for Marine and Environmental Research (CIIMAR) - U.Porto, Portugal
1989 - 2018 Member of the Pedagogical Council Universidade do Porto - Instituto de Ciências Biomédicas de Abel Salazar, Portugal
Projetos

Projeto

Designação Financiadores
2025/01/01 - 2027/12/31 Atlântida II - Coastal Observatory of the North Atlantic of Portugal.
NORTE2030-FEDER-01799200
Investigador
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Interdisciplinary Center for Marine and Environmental Research (CIIMAR) - U.Porto, Portugal

Universidade do Porto - Faculdade de Ciências, Portugal

Universidade do Porto Faculdade de Engenharia, Portugal
Em curso
2025/01/01 - 2026/06/01 Homeless gastropods: unveiling the hidden impact of Ocean Acidification on marine biodiversity through larval SHELL lOSS
2023.12224.PEX
Investigador
Universidade de Aveiro, Portugal

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2020/10 - 2023/10 ATLANTIDA - Platform for the monitoring of the North Atlantic Ocean and tools for the sustainable exploitation of the marine resources
NORTE-01-0145-FEDER-000040
Investigador
Universidade do Porto - Instituto de Ciências Biomédicas de Abel Salazar, Portugal

Interdisciplinary Center for Marine and Environmental Research (CIIMAR) - U.Porto, Portugal

Universidade de Trás-os-Montes e Alto Douro Centro de Investigação e de Tecnologias Agro-Ambientais e Biologicas, Portugal

Universidade do Porto, Portugal
 Comissao de Coordenacao e Desenvolvimento Regional do Norte
Em curso
2021 - 2022 Warming Impacts on Estrogenic and Progestagenic Endocrine Disruptors Effects in Fish Liver - A Proof of Concept Study Using Single- and Novel Multi-Cell 3D Cultures of the European Native Brown Trout.
101038087
Investigador responsável
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
 Horizon 2020
Em curso
2018/06/01 - 2021/05/31 Impacts of global change on environmentally realistic mixtures of endocrine disruptor compounds on the structure and functioning of coastal ecosystems ? Implications for a sustainable environment
PTDC/BIA-ECO/30552/2017
Investigador
Interdisciplinary Center for Marine and Environmental Research (CIIMAR) - U.Porto, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2018 - 2021 GLOBALED - Impacts of global change on environmentally realistic mixtures of endocrine disruptor compounds on the structure and functioning of coastal ecosystems? Implications for a sustainable environment
PTDC/BIA-ECO/30552/2017
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2016/01 - 2018/12 INNOVMAR - Innovation and Sustainability in the Management and Exploitation of Marine Resources
NORTE-01-0145-FEDER-000035
Investigador
Comissao de Coordenacao e Desenvolvimento Regional do Norte
Concluído
2015 - 2018 The Role of Mangroves on the Bioaccumulation and Citogenotoxic Effects of Heavy Metals and Pesticides on the Food Web of a Tropical Coastal System
FDCT 117/2014/A3
Investigador
Interdisciplinary Center for Marine and Environmental Research (CIIMAR) - U.Porto, Portugal

Institute of Science and Environment, University of Saint Joseph (Macao), Macau
2014/04/08 - 2015/06/15 Ultrastructural Studies for the Knowledge and Valorization of Aquatic Organisms | Estudos ultraestruturais para o conhecimento e valorização de organismos aquáticos (EUCVOA)
218-NORTE-07-162-FEDER-000116
Investigador
ICBAS - U.Porto, Portugal
 CCRN - Comissão de Coordenação da Região Norte
Concluído
2014 - 2015 SEI Project: Society, Education and Research | Projeto SEI - Sociedade, Ensino e Investigação
SEI-ICBAS
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Escola Secundaria Filipa De Vilhena, Portugal

Câmara Municipal do Porto, Portugal
 Câmara Municipal do Porto
Concluído
2013 - 2015 MARBIOTECH - Survey of natural substances from marine organisms with potential pharmacological and ecological applications
NORTE-07-0124-FEDER-000047
Investigador
Interdisciplinary Center for Marine and Environmental Research (CIIMAR) - U.Porto, Portugal
 Agência Nacional de Inovação SA
Concluído
2013 - 2015 ECORISK - Ecological risk assessment of oils and hazardous and noxious substances in the NW Portuguese coast
NORTE-07-0124-FEDER-000055
Investigador
Concluído
2011/04 - 2014/09 Peroxisomes, estrogens, and nuclear receptors: cross-talk evaluation in hepatocytes of the trout as a fish model organism - impacts on lipid metabolism
Provided by PTCRIS: 115618
Investigador responsável
Fundação para a Ciência e a Tecnologia
2010/04 - 2013/12 The role of ABC transporter proteins in chemically induced hepatic cancer in zebrafish (Danio rerio)
Provided by PTCRIS: 98791
Investigador
Fundação para a Ciência e a Tecnologia
2010/06 - 2013/11 Ovary apoptosis in zebrafish (Danio rerio): pathways characterization, role in sexual differentiation and as endocrine disruptors chemicals target
Provided by PTCRIS: 102453
Investigador
Fundação para a Ciência e a Tecnologia
2010/04 - 2013/09 The invertebrate repertoire of nuclear receptors: evolutionary and endocrine disruption insights
Provided by PTCRIS: 105199
Investigador
Fundação para a Ciência e a Tecnologia
2008/10 - 2012/06 An integrative study on the toxicopathic lesions in Portuguese estuarine fishes - Assessing injury impact and toxicogenomic implications in experimental models.
Provided by PTCRIS: 70436
Investigador responsável
Fundação para a Ciência e a Tecnologia
2008/08 - 2012/01 Lipid metabolism disruption in marine fish by xenobiotic ligands of peroxisome proliferator-activated receptors (PPARs)
Provided by PTCRIS: 68885
Investigador
Fundação para a Ciência e a Tecnologia
2003 - 2006 Structural and metabolic regulation of fish peroxisomes by estrogenic compounds
POCTI/BSE/46968/2002
Investigador
Interdisciplinary Center for Marine and Environmental Research (CIIMAR) - U.Porto, Portugal
Concluído
1999 - 2002 Effects of sex hormones and xenostrogens (alkylphenols) on liver peroxisomes of brown trout
PRAXIS/P/BIA/14268/98
Investigador
Interdisciplinary Center for Marine and Environmental Research (CIIMAR) - U.Porto, Portugal
Concluído
1996 - 1999 Microanatomical characterization of organs (liver and hepatopancreas) usable as environmental biomarkers
PBIC/C/MAR/ 2254/95
Investigador
Interdisciplinary Center for Marine and Environmental Research (CIIMAR) - U.Porto, Portugal

Universidade do Porto - Instituto de Ciências Biomédicas de Abel Salazar, Portugal
Concluído
1996 - 1999 Influence of age on the central nervous system: microanatomical changes in the cerebellar cortex.
PECS/C/SAU/188/95
Investigador
Universidade do Porto - Instituto de Ciências Biomédicas de Abel Salazar, Portugal
Concluído
1993 - 1995 Morphological characterization of an environmental biomarker: liver of the trout fish (Salmo trutta).
PBIC/C/MAR/1491/92
Investigador
Universidade do Porto - Instituto de Ciências Biomédicas de Abel Salazar, Portugal
Concluído
1993 - 1995 Ultrastructural changes with aging in the granular layer of the cerebral cortex.
PBIC/C/CEN/1114/92
Investigador
Universidade do Porto - Instituto de Ciências Biomédicas de Abel Salazar, Portugal
Concluído
Produções

Publicações

Artigo em conferência
  1. Rodrigo Alves; Célia Lopes; Rosária Seabra; Sofia Esquível; Maria J. Rocha; Eduardo Rocha; Tânia Vieira Madureira. "Thermal Modulation of Cytochrome P450 1A Immunostaining in Single and Mixture PAH-Exposed Brown Trout Hepatocytes". 2026.
    10.3390/proceedings2026146063
  2. Margarida Vilaça; Rosária Seabra; Maria João Rocha; Eduardo Rocha; Célia Lopes. "Effects of Temperature Increase and Benzo[k]fluoranthene on Viability and CYP1A Response in Brown Trout Hepatocytes". 2026.
    10.3390/proceedings2026146065
  3. Sofia Esquível; Rodrigo Alves; Eduardo Rocha; Tânia Vieira Madureira. "Liraglutide Modulates Hepatic Lipid Metabolism in Primary Hepatocytes of Brown Trout". 2026.
    10.3390/proceedings2026146066
  4. Amândio de Barros; Diana Santos; Tiago Lourenço; Célia Lopes; Tânia Vieira Madureira; Eduardo Rocha. "Hepatic PCNA and Caspase-3 Dynamics in Brown Trout Across Reproductive Stages". 2026.
    10.3390/proceedings2026146067
  5. Tiago Lourenço; Maria João Rocha; Eduardo Rocha; Tânia Vieira Madureira. "Pharmaceutical-Induced Disruption of Lipid Metabolism in Brown Trout: Hypolipidemic and Hyperlipidemic Responses". 2026.
    10.3390/proceedings2026146060
  6. Telma Esteves; Fernanda Malhão; Célia Lopes; Eduardo Rocha. "Effects of Collagen Supplementation on Viability, Morphology, and CYP1A Expression in Spheroids from the Rainbow Trout Liver Cell Line RTL-W1". 2026.
    10.3390/proceedings2026146014
Artigo em revista
  1. Amândio de Barros; Diana Santos; Tiago Lourenço; Célia Lopes; Tânia Vieira Madureira; Eduardo Rocha. "Seasonal and Sex-Specific Liver Plasticity in Brown Trout: Estrogen-Responsive Targets and Cell Turnover Dynamics". Animals (2026): https://doi.org/10.3390/ani16071073.
    10.3390/ani16071073
  2. Ana Margarida Esteves; Rodrigo F. Alves; Eduardo Rocha; Maria João Rocha. "PAH pollution in water and blue mussels (Mytilus edulis) along the northern Portuguese Atlantic Coast: Evaluation of ecological and human cancer risks". Marine Pollution Bulletin (2026): http://dx.doi.org/10.1016/j.marpolbul.2025.118744.
    10.1016/j.marpolbul.2025.118744
  3. Rafael Gaio Kulzer; Rodolfo Miguel Silva; Ana Filipa Rocha; João Soares Carrola; Rosária Catarino Seabra; Eduardo Rocha; Karim Erzini; Alberto Teodorico Correia. "Population Structure of the European Seabass (Dicentrarchus labrax) in the Atlantic Iberian Coastal Waters Inferred from Body Morphometrics and Otolith Shape Analyses". Fishes 11 (1) (2026): 16. https://doi.org/10.3390/fishes11010016.
    10.3390/fishes11010016
  4. Inês C. S. Barbosa; Fernanda Malhão; Eduardo Rocha; Tânia Vieira Madureira. "Baseline estrogenic activity in juvenile brown trout liver and primary hepatocytes: Integrated molecular and immunohistochemical analysis". Journal of Comparative Physiology B (2026):
    10.1007/s00360-026-01657-0
  5. Tânia Vieira Madureira; Maria João Rocha; Eduardo Rocha; Maja Jordanova. "The Ohrid Trout: A “Living Fossil” Endemic to Lake Ohrid Left Behind by Science". Hydrobiology (2025): https://doi.org/10.3390/hydrobiology4040032.
    10.3390/hydrobiology4040032
  6. Cassiopée Remfort-Aurat; Ana Margarida Esteves; Eduardo Rocha; Maria João Rocha. "PCB contamination in commercial clams from the North Portuguese Atlantic Coast, the North Sea, and Vietnam: An assessment of potential carcinogenic risks to human health". Marine Pollution Bulletin (2025): http://dx.doi.org/10.1016/j.marpolbul.2025.118484.
    10.1016/j.marpolbul.2025.118484
  7. Tiago Lourenço; Maria João Rocha; Eduardo Rocha; Tânia Vieira Madureira. "A Double Challenge for Fish: The Combined Stress of Warming and Pharmaceuticals in Aquatic Systems". Journal of Xenobiotics (2025): https://doi.org/10.3390/jox15060190.
    10.3390/jox15060190
  8. Margarida Vilaça; Sukanlaya Tantiwisawaruji; Maria João Rocha; Eduardo Rocha. "High Temperature and Ethinylestradiol May Reduce Body Growth, Liver and Hepatocyte Volumes and Lipid Droplets in Adult Male Guppies". Animals (2025): https://doi.org/10.3390/ani15142152.
    10.3390/ani15142152
  9. Margarida Vilaça; Telma Esteves; Rosária Seabra; Eduardo Rocha; Célia Lopes. "Unveiling the Effects of Two Polycyclic Aromatic Hydrocarbons and Two Temperatures on the Trout RTL-W1 Cell Line Expression of Detoxification-Related Target Genes". Journal of Xenobiotics (2025): https://doi.org/10.3390/jox15030084.
    10.3390/jox15030084
  10. Telma Esteves; Fernanda Malhão; Eduardo Rocha; Célia Lopes. "Effects of Benzo[k]fluoranthene at Two Temperatures on Viability, Structure, and Detoxification-Related Genes in Rainbow Trout RTL-W1 Cell Spheroids". Toxics (2025): https://doi.org/10.3390/toxics13040302.
    10.3390/toxics13040302
  11. Frederico Silva; Rodrigo F. Alves; Eduardo Rocha; Maria João Rocha. "Progestin Pollution in Surface Waters of a Major Southwestern European Estuary: The Douro River Estuary (Iberian Peninsula)". Toxics (2025): https://doi.org/10.3390/toxics13030225.
    10.3390/toxics13030225
  12. Uroš Ljubobratovic; Božidar Raškovic; Ákos Horváth; Georgina Fazekas; Milica Markelic; Tijana Ristovic; Zoltán Nagy; et al. "Effect of sex isolation on the reproduction of pikeperch (Sander lucioperca L.) submitted to the cycle shift from outdoor to fully controlled conditions". Aquaculture (2025): http://dx.doi.org/10.1016/j.aquaculture.2024.741903.
    10.1016/j.aquaculture.2024.741903
  13. Albina D. Resende; Alexandre Lobo-da-Cunha; Rocha, Eduardo. Autor correspondente: Albina D. Resende. "Enzyme activities of brown trout liver and kidney peroxisomes after subacute paraquat exposure". Scientific Letters 1 1 (2025): 4. https://publicacoes.cespu.pt/index.php/sl/article/view/278.
    Acesso aberto • Publicado • 10.48797/sl.2025.278
  14. Margarida Vilaça; Célia Lopes; Rosária Seabra; Eduardo Rocha. "17a-Ethynylestradiol and Levonorgestrel Exposure of Rainbow Trout RTL-W1 Cells at 18 °C and 21 °C Mainly Reveals Thermal Tolerance, Absence of Estrogenic Effects, and Progestin-Induced Upregulation of Detoxification Genes". Genes (2024): https://doi.org/10.3390/genes15091189.
    10.3390/genes15091189
  15. Rodrigo F. Alves; Célia Lopes; Eduardo Rocha; Tânia Vieira Madureira. "Estrogenic Responsiveness of Brown Trout Primary Hepatocyte Spheroids to Environmental Levels of 17a-Ethinylestradiol". Journal of Xenobiotics (2024): https://doi.org/10.3390/jox14030060.
    10.3390/jox14030060
  16. Rocha, Maria João; Rocha, Eduardo. "Pesticides in a temperate coastal lagoon in southwest Europe (Ria de Aveiro, Portugal) - Risk assessment and acute assays with Artemia and Daphnia". Emerging Contaminants 10 2 (2024): 100282. http://dx.doi.org/10.1016/j.emcon.2023.100282.
    10.1016/j.emcon.2023.100282
  17. Tiago Lourenço; Eduardo Rocha; José Fernando Gonçalves; Maria João Rocha; Tânia Vieira Madureira. "A Proof-of-Concept for a Hypolipidemic Brown Trout Model". Toxics (2024): https://doi.org/10.3390/toxics12030219.
    10.3390/toxics12030219
  18. Freitas, Vânia; Santos, Diana; Silva, Diogo M.; Cunha, Jacinto; Rodrigues, Sabrina M.; Neves, Vanessa; Rocha, Eduardo; Martinho, Filipe; Ramos, Sandra. "Spatial and temporal patterns of gonadal maturation and spawning in European flounder Platichthys flesus at its southern continental edge". Fisheries Research 269 (2024): 106864. http://dx.doi.org/10.1016/j.fishres.2023.106864.
    10.1016/j.fishres.2023.106864
  19. Tânia Vieira Madureira; Diana Santos; Tiago Simões; Marco F. L. Lemos; Eduardo Rocha. "Liver and Plasma Fatty Acid Characterization in Cultured Brown Trout at Distinct Reproductive Stages". Biology (2023): https://doi.org/10.3390/biology12111434.
    10.3390/biology12111434
  20. Rodrigo F. Alves; Célia Lopes; Eduardo Rocha; Tânia V. Madureira. "A Step Forward in the Characterization of Primary Brown Trout Hepatocytic Spheroids as Experimental Models". Animals (2023): https://doi.org/10.3390/ani13142277.
    10.3390/ani13142277
  21. Maria João Rocha; Eduardo Rocha. "Chemical Survey and Risk Assessment of 56 Pesticides in the Sado River Estuary (Iberian Peninsula, Portugal)". Toxics (2023): https://doi.org/10.3390/toxics11050457.
    10.3390/toxics11050457
  22. Rocha MJ; Rocha E. "Chemical monitoring and risk assessment of 56 pesticides in the Ave River and adjoining Atlantic coastline (Iberian Peninsula, Portugal).". Marine pollution bulletin (2023): http://europepmc.org/abstract/med/37015172.
    10.1016/j.marpolbul.2023.114844
  23. Rosária Seabra; Fernanda Malhão; Alexandra Correia; Carla Costa; Anake Kijjoa; Eduardo Rocha. "Effects and Mechanisms of Action of Preussin, a Marine Fungal Metabolite, against the Triple-Negative Breast Cancer Cell Line, MDA-MB-231, in 2D and 3D Cultures". Marine Drugs (2023): https://doi.org/10.3390/md21030166.
    10.3390/md21030166
  24. Rodrigo F. Alves; Eduardo Rocha; Tânia V. Madureira. "Fish hepatocyte spheroids – A powerful (though underexplored) alternative in vitro model to study hepatotoxicity". Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 262 (2022): 109470-109470. http://dx.doi.org/10.1016/j.cbpc.2022.109470.
    10.1016/j.cbpc.2022.109470
  25. Pereira IL; Lopes C; Rocha E; Madureira TV. "Establishing brown trout primary hepatocyte spheroids as a new alternative experimental model-Testing the effects of 5a-dihydrotestosterone on lipid pathways.". Aquatic toxicology (Amsterdam, Netherlands) (2022): http://europepmc.org/abstract/med/36327687.
    10.1016/j.aquatox.2022.106331
  26. Sukanlaya Tantiwisawaruji; Maria J. Rocha; Ana Silva; Miguel A. Pardal; Uthaiwan Kovitvadhi; Eduardo Rocha. "A Stereological Study of the Three Types of Ganglia of Male, Female, and Undifferentiated Scrobicularia plana (Bivalvia)". Animals (2022): https://doi.org/10.3390/ani12172248.
    10.3390/ani12172248
  27. Fernanda Malhão; Ana Macedo; Alice Ramos; Eduardo Rocha. "Morphometrical, Morphological, and Immunocytochemical Characterization of a Tool for Cytotoxicity Research: 3D Cultures of Breast Cell Lines Grown in Ultra-Low Attachment Plates". Toxics (2022): https://doi.org/10.3390/toxics10080415.
    10.3390/toxics10080415
  28. Maria João Rocha; Frederico Silva; Eduardo Rocha. "Annual Evaluation of 17 Oestrogenic Endocrine Disruptors and Hazard Indexes in the Douro River Estuary—The Atlantic Discharge of the Highest-Flow River of Southwestern Europe". Water (2022): https://doi.org/10.3390/w14132046.
    10.3390/w14132046
  29. Maria Rocha; Eduardo Rocha. "Synthetic Progestins in Waste and Surface Waters: Concentrations, Impacts and Ecological Risk". Toxics 10 4 (2022): 163-163. https://doi.org/10.3390/toxics10040163.
    10.3390/toxics10040163
  30. Katerina Rebok; Maja Jordanova; Júlia Azevedo; Eduardo Rocha. "First Report and 3D Reconstruction of a Presumptive Microscopic Liver Lipoma in a Black Barbel (Barbus balcanicus) from the River Bregalnica in the Republic of North Macedonia". Applied Sciences (2021): https://doi.org/10.3390/app11188392.
    10.3390/app11188392
  31. Fernanda Malhão; Ana Catarina Macedo; Carla Costa; Eduardo Rocha; Alice Abreu Ramos. "Fucoxanthin Holds Potential to Become a Drug Adjuvant in Breast Cancer Treatment: Evidence from 2D and 3D Cell Cultures". Molecules 26 14 (2021): 4288-4288. https://doi.org/10.3390/molecules26144288.
    10.3390/molecules26144288
  32. Diana Santos; Eduardo Rocha; Fernanda Malhão; Célia Lopes; José F. Gonçalves; Tânia V. Madureira. "Multi-Parametric Portfolio to Assess the Fitness and Gonadal Maturation in Four Key Reproductive Phases of Brown Trout". Animals (2021): https://doi.org/10.3390/ani11051290.
    10.3390/ani11051290
  33. Rocha MJ; Ribeiro AB; Campos D; Rocha E. "Temporal-spatial survey of PAHs and PCBs in the Atlantic Iberian northwest coastline, and evaluation of their sources and risks for both humans and aquatic organisms.". Chemosphere (2021): http://europepmc.org/abstract/med/33901888.
    10.1016/j.chemosphere.2021.130506
  34. Rocha, Eduardo. "Deciphering influences of testosterone and dihydrotestosterone on lipid metabolism genes using brown trout primary hepatocytes". Aquatic Toxicology (2021): https://www.sciencedirect.com/science/article/pii/S0166445X21000783.
    10.1016/j.aquatox.2021.105819
  35. Rocha MJ; Rocha E. "Concentrations, sources and risks of PAHs in dissolved and suspended material particulate fractions from the Northwest Atlantic Coast of the Iberian Peninsula.". Marine pollution bulletin (2021): http://europepmc.org/abstract/med/33610110.
    10.1016/j.marpolbul.2021.112143
  36. Fernanda Malhão; Alice Abreu Ramos; Ana Catarina Macedo; Eduardo Rocha. "Cytotoxicity of Seaweed Compounds, Alone or Combined to Reference Drugs, against Breast Cell Lines Cultured in 2D and 3D". Toxics 9 2 (2021): 24-24. https://doi.org/10.3390/toxics9020024.
    10.3390/toxics9020024
  37. Alice A. Ramos; Bruno Castro-Carvalho; Maria Prata-Sena; Fernanda Malhão; Suradet Buttachon; Tida Dethoup; Anake Kijjoa; Eduardo Rocha. "Can marine-derived fungus Neosartorya siamensis KUFA 0017 extract and its secondary metabolites enhance antitumor activity of doxorubicin? An in vitro survey unveils interactions against lung cancer cells". Environmental Toxicology (2020): https://doi.org/10.1002/tox.22886.
    10.1002/tox.22886
  38. Fernanda Malhão; Alice A. Ramos; Eduardo Rocha. "Cytotoxic and Anti-Proliferative Effects of Fucosterol, Alone and in Combination with Doxorubicin, in 2D and 3D Cultures of Triple-Negative Breast Cancer Cells". Medical Sciences Forum 2 1 (2020): 14-14. https://doi.org/10.3390/CAHD2020-08600.
    10.3390/CAHD2020-08600
  39. Ana Catarina Lopes; Pedro Fontes Oliveira; Soraia Pinto; Carolina Almeida; Maria João Pinho; Rosália Sá; Eduardo Rocha; Alberto Barros; Mário Sousa. "Discordance between human sperm quality and telomere length following differential gradient separation/swim-up". Journal of Assisted Reproduction and Genetics (2020): https://doi.org/10.1007/s10815-020-01897-1.
    10.1007/s10815-020-01897-1
  40. Lopes C; Madureira TV; Gonçalves JF; Rocha E. "Disruption of classical estrogenic targets in brown trout primary hepatocytes by the model androgens testosterone and dihydrotestosterone.". Aquatic toxicology (Amsterdam, Netherlands) (2020): http://europepmc.org/abstract/med/32882451.
    10.1016/j.aquatox.2020.105586
  41. Maja Jordanova; Katerina Rebok; Eduardo Rocha; Maria João Rocha. "Changes in copper load in hepatocytes of Ohrid trout in relation to the ovarian maturation cycle". Toxicological & Environmental Chemistry (2020): 1-13. https://doi.org/10.1080/02772248.2020.1781854.
    10.1080/02772248.2020.1781854
  42. Maria Leonor Ferrão; Maria João Rocha; Eduardo Rocha. "Histological characterization of the maturation stages of the ovarian follicles of the goldfish Carassius auratus (Linnaeus, 1758)". Anatomia, Histologia, Embryologia (2020): https://doi.org/10.1111/ahe.12570.
    10.1111/ahe.12570
  43. Rocha, Eduardo. "Histology and design-based estimation of hepatocellularity and volumes of hepatocytes in control and ethynylestradiol exposed males of platyfish (Xiphophorus maculatus).". Tissue & cell (2020): http://europepmc.org/abstract/med/32223955.
    10.1016/j.tice.2019.101327
  44. Almeida TP; Ramos AA; Ferreira J; Azqueta A; Rocha E. "Bioactive Compounds from Seaweed with Anti-Leukemic Activity: A Mini-Review on Carotenoids and Phlorotannins.". Mini-Reviews in Medicinal Chemistry (2020): http://europepmc.org/abstract/med/30854962.
    10.2174/1389557519666190311095655
  45. Vieira Madureira, Tânia; Costa, Joana Luísa; Malhão, Fernanda; Lopes, Célia; Gonçalves, José F.; Rocha, Eduardo. "Design of a multi-parametric profile for assessing the acclimation period of juvenile brown trout after an acute transport to new housing environment". Applied Animal Behaviour Science 219 (2019): 104835. http://dx.doi.org/10.1016/j.applanim.2019.104835.
    10.1016/j.applanim.2019.104835
  46. Fernanda Malhão; Alice A. Ramos; Suradet Buttachon; Tida Dethoup; Anake Kijjoa; Eduardo Rocha. "Cytotoxic and Antiproliferative Effects of Preussin, a Hydroxypyrrolidine Derivative from the Marine Sponge-Associated Fungus Aspergillus candidus KUFA 0062, in a Panel of Breast Cancer Cell Lines and Using 2D and 3D Cultures". Marine Drugs (2019): https://doi.org/10.3390/md17080448.
    10.3390/md17080448
  47. Maria João Rocha; Tânia V. Madureira; Carla Sofia Venade; Irene Martins; Joana Campos; Eduardo Rocha. "Presence of estrogenic endocrine disruptors in three European estuaries in Northwest Iberian Peninsula (Portugal)". Toxicological & Environmental Chemistry (2019): 1-21. https://doi.org/10.1080/02772248.2019.1692019.
    10.1080/02772248.2019.1692019
  48. Cardoso PG; Resende-de-Oliveira R; Rocha E. "Combined effects of increased temperature and levonorgestrel exposure on zebrafish female liver, using stereology and immunohistochemistry against catalase, CYP1A, HSP90 and vitellogenin.". Environmental pollution (Barking, Essex : 1987) (2019): http://europepmc.org/abstract/med/31252103.
    10.1016/j.envpol.2019.06.058
  49. Alice A. Ramos; Tânia Almeida; Bruna Lima; Eduardo Rocha. "Cytotoxic activity of the seaweed compound fucosterol, alone and in combination with 5-fluorouracil, in colon cells using 2D and 3D culturing". Journal of Toxicology and Environmental Health, Part A 82 9 (2019): 537-549. https://doi.org/10.1080/15287394.2019.1634378.
    10.1080/15287394.2019.1634378
  50. Carrola JS; Fontainhas-Fernandes A; Rocha E. "Uncommon hepatic macrophagic foamy-cell nodules in Iberian barbel (Luciobarbus bocagei Steindachner, 1864) from the Vizela River (Portugal).". Microscopy research and technique (2019): http://europepmc.org/abstract/med/30946508.
    10.1002/jemt.23260
  51. Tânia Vieira Madureira; Ivone Pinheiro; Fernanda Malhão; L. Filipe C. Castro; Eduardo Rocha; Ralph Urbatzka. "Silencing of PPARaBb mRNA in brown trout primary hepatocytes: effects on molecular and morphological targets under the influence of an estrogen and a PPARa agonist". Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology 229 (2019): 1-9. https://doi.org/10.1016/j.cbpb.2018.12.001.
    10.1016/j.cbpb.2018.12.001
  52. Rocha, Maria João; Rocha, Eduardo. "Estrona, estradiol, etinilestradiol e diclofenac em águas superficiais portuguesas e sua contextualização internacional". Revista Recursos Hídricos 40 1 (2019): 19-39. http://dx.doi.org/10.5894/rh40n1-d2.
    10.5894/rh40n1-d2
  53. C. Cruzeiro; A. Ramos; E.M. Loganimoce; F. Arenas; E. Rocha; P.G. Cardoso. "Genotoxic effects of combined multiple stressors on Gammarus locusta haemocytes: Interactions between temperature, pCO2 and the synthetic progestin levonorgestrel". Environmental Pollution 245 (2019): 864-872. https://doi.org/10.1016/j.envpol.2018.11.070.
    10.1016/j.envpol.2018.11.070
  54. Raškovic B; Cruzeiro C; Poleksic V; Rocha E. "Estimating volumes from common carp hepatocytes using design-based stereology and examining correlations with profile areas: Revisiting a nutritional assay and unveiling guidelines to microscopists.". Microscopy research and technique (2019): http://europepmc.org/abstract/med/30730589.
    10.1002/jemt.23228
  55. Rocha, Eduardo. "Histochemical evaluation of iron content in the liver of wild female ohrid trout (Salmo letnica Kar.) along the breeding cycle.". Contributions, Section of Natural, Mathematical and Biotechnical Sciences (2018):
    10.20903/csnmbs.masa.2018.39.2.125
  56. Cardoso PG; Rodrigues D; Madureira TV; Rocha MJ; Rocha E. "Histopathological Evaluation of Combined Impacts of the Synthetic Progestin Levonorgestrel and Temperature on the Female Zebrafish Maturation Using a Semi-quantitative Grading Analysis-Is it Enough?". Bulletin of environmental contamination and toxicology (2018): http://europepmc.org/abstract/med/30187092.
    10.1007/s00128-018-2436-z
  57. Madureira TV; Malhão F; Simões T; Pinheiro I; Lopes C; Gonçalves JF; Urbatzka R; et al. "Sex-steroids and hypolipidemic chemicals impacts on brown trout lipid and peroxisome signaling - Molecular, biochemical and morphological insights.". Comparative biochemistry and physiology. Toxicology & pharmacology : CBP (2018): http://europepmc.org/abstract/med/29885532.
    10.1016/j.cbpc.2018.06.001
  58. P.G. Cardoso; E.M. Loganimoce; T. Neuparth; M.J. Rocha; E. Rocha; F. Arenas. "Interactive effects of increased temperature, p CO 2 and the synthetic progestin levonorgestrel on the fitness and breeding of the amphipod Gammarus locusta". Environmental Pollution 236 (2018): 937-947. https://doi.org/10.1016/j.envpol.2017.10.065.
    10.1016/j.envpol.2017.10.065
  59. Ferreira J; Ramos AA; Almeida T; Azqueta A; Rocha E. "Drug resistance in glioblastoma and cytotoxicity of seaweed compounds, alone and in combination with anticancer drugs: A mini review.". Phytomedicine : international journal of phytotherapy and phytopharmacology (2018): http://europepmc.org/abstract/med/30195884.
    10.1016/j.phymed.2018.04.062
  60. Buttachon S; Ramos AA; Inácio Â; Dethoup T; Gales L; Lee M; Costa PM; et al. "Bis-Indolyl Benzenoids, Hydroxypyrrolidine Derivatives and Other Constituents from Cultures of the Marine Sponge-Associated Fungus Aspergillus candidus KUFA0062.". Marine drugs (2018): http://europepmc.org/abstract/med/29642369.
    10.3390/md16040119
  61. Sousa, Sisandra; Rocha, Maria J.; Rocha, Eduardo. "Characterization and spatial relationships of the hepatic vascular–biliary tracts, and their associated pancreocytes and macrophages, in the model fish guppy ( Poecilia reticulata ): A study of serial sections by light microscopy". Tissue and Cell 50 (2018): 104-113. http://dx.doi.org/10.1016/j.tice.2017.12.009.
    10.1016/j.tice.2017.12.009
  62. Almeida TP; Ferreira J; Vettorazzi A; Azqueta A; Rocha E; Ramos AA. "Cytotoxic activity of fucoxanthin, alone and in combination with the cancer drugs imatinib and doxorubicin, in CML cell lines.". Environmental toxicology and pharmacology (2018): http://europepmc.org/abstract/med/29518678.
    10.1016/j.etap.2018.02.006
  63. Sukanlaya Tantiwisawaruji; Uthaiwan Kovitvadhi; Miguel Ângelo Pardal; Maria João Rocha; Eduardo Rocha. "Qualitative and quantitative insights into the 3D microanatomy of the nervous ganglia of Scrobicularia plana (Bivalvia: Tellinoidea: Semelidae)". Molluscan Research (2018): 1-8. https://doi.org/10.1080/13235818.2017.1368914.
    10.1080/13235818.2017.1368914
  64. Castro-Carvalho B; Ramos AA; Prata-Sena M; Malhão F; Moreira M; Gargiulo D; Dethoup T; et al. "Marine-derived Fungi Extracts Enhance the Cytotoxic Activity of Doxorubicin in Nonsmall Cell Lung Cancer Cells A459.". Pharmacognosy research (2017): http://europepmc.org/abstract/med/29333049.
    10.4103/pr.pr_57_17
  65. Rocha, Eduardo. "Overview of the neurocytology of ganglia and identification of putative serotonin- and dopamine-secreting neurons in the bivalve peppery furrow shell (Scrobicularia plana)". Journal of Shellfish Research (2017): http://www.bioone.org/doi/abs/10.2983/035.036.0304.
    10.2983/35.036.0300
  66. "Testosterone-induced modulation of peroxisomal morphology and peroxisome-related gene expression in brown trout (Salmo trutta f. fario) primary hepatocytes.". Aquatic toxicology (Amsterdam, Netherlands) (2017): http://europepmc.org/abstract/med/29032351.
    10.1016/j.aquatox.2017.09.026
  67. P.G. Cardoso; D. Rodrigues; T.V. Madureira; N. Oliveira; M.J. Rocha; E. Rocha. "Warming modulates the effects of the endocrine disruptor progestin levonorgestrel on the zebrafish fitness, ovary maturation kinetics and reproduction success". Environmental Pollution 229 (2017): 300-311. https://doi.org/10.1016/j.envpol.2017.05.090.
    10.1016/j.envpol.2017.05.090
  68. Eduarda Lopes-Costa; Mariana Abreu; Daniela Gargiulo; Eduardo Rocha; Alice A. Ramos. "Anticancer effects of seaweed compounds fucoxanthin and phloroglucinol, alone and in combination with 5-fluorouracil in colon cells". Journal of Toxicology and Environmental Health, Part A (2017): 1-12. https://doi.org/10.1080/15287394.2017.1357297.
    10.1080/15287394.2017.1357297
  69. "PAHs in water and surface sediments from Douro River estuary and Porto Atlantic coast (Portugal)-impacts on human health.". Environmental monitoring and assessment (2017): http://europepmc.org/abstract/med/28762147.
    10.1007/s10661-017-6137-6
  70. "Determination of 54 pesticides in waters of the Iberian Douro River estuary and risk assessment of environmentally relevant mixtures using theoretical approaches and Artemia salina and Daphnia magna bioassays.". Ecotoxicology and environmental safety (2017): http://europepmc.org/abstract/med/28732295.
    10.1016/j.ecoenv.2017.07.010
  71. Santos M; Dias-Pereira P; Correia-Gomes C; Marcos R; de Matos A; Rocha E; Lopes C. "Use of the optical disector in canine mammary simple and complex carcinomas.". (2017): http://europepmc.org/abstract/med/28586148.
    10.1111/apm.12717
  72. Silva C; Pires-Luís AS; Rocha E; Bartosch C; Lopes JM. "Phenotypic Intratumoral Heterogeneity of Endometrial Carcinomas.". (2017): http://europepmc.org/abstract/med/28582348.
    10.1097/pgp.0000000000000400
  73. Rebok K; Jordanova M; Slavevska-Stamenkovic V; Ivanova L; Kostov V; Stafilov T; Rocha E. "Frequencies of erythrocyte nuclear abnormalities and of leucocytes in the fish Barbus peloponnesius correlate with a pollution gradient in the River Bregalnica (Macedonia).". (2017): http://europepmc.org/abstract/med/28281072.
    10.1007/s11356-017-8665-6
  74. Madureira TV; Pinheiro I; Malhão F; Lopes C; Urbatzka R; Castro LFC; Rocha E. "Cross-interference of two model peroxisome proliferators in peroxisomal and estrogenic pathways in brown trout hepatocytes.". (2017): http://europepmc.org/abstract/med/28415051.
    10.1016/j.aquatox.2017.04.001
  75. Madureira TV; Pinheiro I; de Paula Freire R; Rocha E; Castro LF; Urbatzka R. "Genome specific PPARaB duplicates in salmonids and insights into estrogenic regulation in brown trout.". (2017): http://europepmc.org/abstract/med/28414176.
    10.1016/j.cbpb.2017.04.005
  76. Resende AD; Lobo-da-Cunha A; Malhão F; Rocha E. "Seasonal and Morphological Variations of Brown Trout (Salmo trutta f. fario) Kidney Peroxisomes: A Stereological Study.". (2016): http://europepmc.org/abstract/med/27998362.
    10.1017/s1431927616011995
  77. Lopes, Célia; Madureira, Tânia Vieira; Ferreira, Nádia; Pinheiro, Ivone; Castro, L. Filipe C.; Rocha, Eduardo. "Peroxisome proliferator-activated receptor gamma (PPARd) in brown trout: Interference of estrogenic and androgenic inputs in primary hepatocytes". Environmental Toxicology and Pharmacology 46 (2016): 328-336. http://dx.doi.org/10.1016/j.etap.2016.08.009.
    10.1016/j.etap.2016.08.009
  78. Rocha, Eduardo. "Cytotoxic activity of Secondary Metabolites from Marine-derived Fungus Neosartorya siamensis in Human Cancer Cells.". (2016): http://europepmc.org/abstract/med/27530464.
    10.1002/ptr.5696
  79. Cruzeiro C; Pardal MÂ; Rodrigues-Oliveira N; Castro LF; Rocha E; Rocha MJ. "Multi-matrix quantification and risk assessment of pesticides in the longest river of the Iberian peninsula.". (2016): http://europepmc.org/abstract/med/27501425.
  80. Gonçalves, Catarina; Ferreira, Sílvia A; Correia, Alexandra L; Lopes, Célia; Fleming, Carolina E; Rocha, Eduardo; Vilanova, Manuel; Gama, Miguel. "Potential of mannan or dextrin nanogels as vaccine carrier/adjuvant systems". Journal of Bioactive and Compatible Polymers 31 5 (2016): 453-466. http://dx.doi.org/10.1177/0883911516631354.
    10.1177/0883911516631354
  81. Cruzeiro, Catarina; Rocha, Eduardo; Pardal, Miguel Ângelo; Rocha, Maria João. "Seasonal-spatial survey of pesticides in the most significant estuary of the Iberian Peninsula - the Tagus River estuary". Journal of Cleaner Production 126 (2016): 419-427. http://dx.doi.org/10.1016/j.jclepro.2016.03.005.
    10.1016/j.jclepro.2016.03.005
  82. Jordanova M; Rebok K; Malhão F; Rocha MJ; Rocha E. "Seasonal changes in hepatocytic lipid droplets, glycogen deposits, and rough endoplasmic reticulum along the natural breeding cycle of female ohrid trout (Salmo letnica Kar.)-A semiquantitative ultrastructural study.". (2016): http://europepmc.org/abstract/med/27223583.
    10.1002/jemt.22687
  83. Rocha MJ; Cruzeiro C; Reis M; Pardal MÂ; Rocha E. "Pollution by oestrogenic endocrine disruptors and ß-sitosterol in a south-western European river (Mira, Portugal).". (2016): http://europepmc.org/abstract/med/27004433.
    10.1007/s10661-016-5236-0
  84. Luzio A; Monteiro SM; Rocha E; Fontaínhas-Fernandes AA; Coimbra AM. "Development and recovery of histopathological alterations in the gonads of zebrafish (Danio rerio) after single and combined exposure to endocrine disruptors (17a-ethinylestradiol and fadrozole).". (2016): http://europepmc.org/abstract/med/27002526.
    10.1016/j.aquatox.2016.03.014
  85. Cruzeiro C; Rodrigues-Oliveira N; Velhote S; Pardal MÂ; Rocha E; Rocha MJ. "Development and application of a QuEChERS-based extraction method for the analysis of 55 pesticides in the bivalve Scrobicularia plana by GC-MS/MS.". (2016): http://europepmc.org/abstract/med/27032408.
  86. Rocha MJ; Cruzeiro C; Reis M; Pardal MÂ; Rocha E. "Pollution by endocrine disruptors in a southwest European temperate coastal lagoon (Ria de Aveiro, Portugal).". (2016): http://europepmc.org/abstract/med/26787270.
    10.1007/s10661-016-5114-9
  87. Cruzeiro C; Rocha E; Pardal MÂ; Rocha MJ. "Environmental assessment of pesticides in the Mondego River Estuary (Portugal).". (2016): http://europepmc.org/abstract/med/26763320.
    10.1016/j.marpolbul.2015.12.013
  88. Marcos R; Lopes C; Malhão F; Correia-Gomes C; Fonseca S; Lima M; Gebhardt R; Rocha E. "Stereological assessment of sexual dimorphism in the rat liver reveals differences in hepatocytes and Kupffer cells but not hepatic stellate cells.". (2016): http://europepmc.org/abstract/med/26892301.
    10.1111/joa.12448
  89. Cruzeiro C; Lopes-Marques M; Ruivo R; Rodrigues-Oliveira N; Santos MM; Rocha MJ; Rocha E; Castro LF. "A mollusk VDR/PXR/CAR-like (NR1J) nuclear receptor provides insight into ancient detoxification mechanisms.". (2016): http://europepmc.org/abstract/med/26921727.
    10.1016/j.aquatox.2016.02.007
  90. Goncalves C; Cunha M; Rocha E; Fernandes S; Silva J; Ferraz L; Oliveira C; Barros A; Sousa M. "Y-chromosome microdeletions in nonobstructive azoospermia and severe oligozoospermia.". (2016): http://europepmc.org/abstract/med/26908064.
    10.4103/1008-682X.172827
  91. Madureira TV; Castro LF; Rocha E. "Acyl-coenzyme A oxidases 1 and 3 in brown trout (Salmo trutta f. fario): Can peroxisomal fatty acid ß-oxidation be regulated by estrogen signaling?". (2016): http://europepmc.org/abstract/med/26508171.
    10.1007/s10695-015-0146-6
  92. Ramos AA; Castro-Carvalho B; Prata-Sena M; Dethoup T; Buttachon S; Kijjoa A; Rocha E. "Crude Extracts of Marine-derived and Soil Fungi of the Genus Neosartorya Exhibit Selective Anticancer Activity by Inducing Cell Death in Colon, Breast and Skin Cancer Cell Lines.". (2016): http://europepmc.org/abstract/med/26941530.
    10.4103/0974-8490.171105
  93. Cruzeiro C; Pardal MÂ; Rocha E; Rocha MJ. "Occurrence and seasonal loads of pesticides in surface water and suspended particulate matter from a wetland of worldwide interest-the Ria Formosa Lagoon, Portugal.". (2015): http://europepmc.org/abstract/med/26439122.
    10.1007/s10661-015-4824-8
  94. Catarina Cruzeiro; Eduardo Rocha; Miguel Ângelo Pardal; Maria João Rocha. "Uncovering seasonal patterns of 56 pesticides in surface coastal waters of the Ria Formosa lagoon (Portugal), using a GC-MS method". International Journal of Environmental Analytical Chemistry 95 14 (2015): 1370-1384. http://dx.doi.org/10.1080/03067319.2015.1100724.
    10.1080/03067319.2015.1100724
  95. Luzio A; Monteiro SM; Garcia-Santos S; Rocha E; Fontaínhas-Fernandes AA; Coimbra AM. "Zebrafish sex differentiation and gonad development after exposure to 17a-ethinylestradiol, fadrozole and their binary mixture: A stereological study.". (2015): http://europepmc.org/abstract/med/26240953.
    10.1016/j.aquatox.2015.07.015
  96. Rocha MJ; Cruzeiro C; Reis M; Pardal MÂ; Rocha E. "Toxicological relevance of endocrine disruptors in the Tagus River estuary (Lisbon, Portugal).". (2015): http://europepmc.org/abstract/med/26135642.
    10.1007/s10661-015-4679-z
  97. Tantiwisawaruji S; Silva A; Kovitvadhi U; Pardal MA; Rocha MJ; Rocha E; Sukanlaya Tantiwisawaruji; et al. "A Stereological Estimation of the Nervous Ganglia Volumes and Number of Neurons in the Peppery Furrow Shell Scrobicularia plana (da Costa, 1778).". Microsc Microanal 21 S5 (2015): 99-100. http://europepmc.org/abstract/med/26227730.
    10.1017/S1431927615014300
  98. Abreu Ramos A; Malhão F; Ferreira A; Alves Â; Castro-Carvalho B; Prata-Sena M; Gargiulo D; et al. "Marine and Soil Fungi Extracts with Antiproliferative Activity Induce Morphological Alterations in Breast Cancer Cells.". Microsc Microanal 21 S5 (2015): 83-84. http://europepmc.org/abstract/med/26227722.
    10.1017/S1431927615014221
  99. Batista-Pinto C; Lobo-da-Cunha A; Malhão F; Resende AD; Rocha MJ; Rocha E; Carla Batista-Pinto; et al. "Kinetics of the Metabolic and Morphological Alterations in Brown Trout Hepatic Peroxisomes Under Estradiol Influence.". Microsc Microanal 21 S5 (2015): 61-62. http://europepmc.org/abstract/med/26227711.
    10.1017/S1431927615014117
  100. Sousa ML; Figueiredo F; Pinheiro C; Silva A; Malhao F; Rocha MJ; Rocha E; Urbatzka R. "Morphological and molecular effects of cortisol and ACTH on zebrafish stage I and II follicles.". (2015): http://europepmc.org/abstract/med/26316549.
  101. Madureira TV; Malhão F; Lopes C; Pinheiro I; Gonçalves JF; Rocha E; Tânia V. Madureira; et al. "Morphological Alterations Caused by Estrogenic and Anti-Estrogenic Signaling in Peroxisomes of Primary Brown Trout Hepatocytes - Stereological Approach Using Catalase Immunofluorescence.". Microsc Microanal 21 S5 (2015): 73-74. http://europepmc.org/abstract/med/26227717.
    10.1017/S1431927615014178
  102. Sá R; Cunha M; Rocha E; Barros A; Sousa M. "Sperm DNA fragmentation is related to sperm morphological staining patterns.". (2015): http://europepmc.org/abstract/med/26278809.
    10.1016/j.rbmo.2015.06.019
  103. Ivone Pinheiro; Fernanda Malhão; Tânia V. Madureira; Maria João Rocha; Rogério A.F. Monteiro; Eduardo Rocha; Pinheiro I; et al. "Ethinylestradiol Exposure of Primary Culture Brown Trout Hepatocytes Induce Morphological Changes in Peroxisomes". Microsc Microanal 21 S5 (2015): 81-82. http://dx.doi.org/10.1017/s143192761501421x.
    10.1017/s143192761501421x
  104. Eduardo Rocha; Albina D. Resende; Maria J. Rocha; Fernanda Malhão; Rogério A.F. Monteiro; Alexandre Lobo-da-Cunha; Rocha E; et al. "Stereology of Brown Trout Liver Peroxisomes at Vitellogenesis and Pre-spawning Strengthens the Hypothesis of Their Regulation by Sex Steroids". Microsc Microanal 21 S5 (2015): 87-88. http://dx.doi.org/10.1017/s1431927615014245.
    10.1017/s1431927615014245
  105. Ana Sílvia Pires-Luís; Eduardo Rocha; Carla Bartosch; Elsa Oliveira; Joaquina Silva; Alberto Barros; Rosália Sá; et al. "A stereological study on organelle distribution in human oocytes at prophase I". Zygote (2015): 1-9. http://dx.doi.org/10.1017/s0967199415000258.
    10.1017/s0967199415000258
  106. Tânia V. Madureira; Fernanda Malhão; Cláudia Guimarães; Célia Lopes; Eduardo Rocha; Madureira TV; Malhão F; et al. "Uncovering Morphological Interferences Caused by Androgen Inputs in Peroxisomes from Primary Brown Trout Hepatocytes Using Catalase Immunofluorescence". Microsc Microanal 21 S5 (2015): 71-72. http://dx.doi.org/10.1017/s1431927615014166.
    10.1017/s1431927615014166
  107. Madureira TV; Lopes C; Malhão F; Rocha E. "Estimation of volume densities of hepatocytic peroxisomes in a model fish: catalase conventional immunofluorescence versus cytochemistry for electron microscopy.". (2015): http://europepmc.org/abstract/med/25431324.
    10.1002/jemt.22455
  108. Bucar S; Gonçalves A; Rocha E; Barros A; Sousa M; Sá R. "DNA fragmentation in human sperm after magnetic-activated cell sorting.". (2015): http://europepmc.org/abstract/med/25374393.
    10.1007/s10815-014-0370-5
  109. Maria João Bessa; Marta Costa Rego; Eduardo Rocha; João Pessanha; Carla leal; Joana Mesquita Guimarães; José Carlos Oliveira; Mário Sousa. "Semen parameters and their influence on pregnancy after assisted reproduction: Report of the Hospital Centre of Porto". Revista Internacional de Andrología 13 1 (2015): 27-36. http://dx.doi.org/10.1016/j.androl.2014.05.001.
    10.1016/j.androl.2014.05.001
  110. Lopes-Marques M; Delgado IL; Ruivo R; Torres Y; Sainath SB; Rocha E; Cunha I; Santos MM; Castro LF. "The Origin and Diversity of Cpt1 Genes in Vertebrate Species.". (2015): http://europepmc.org/abstract/med/26421611.
    10.1371/journal.pone.0138447
  111. Padua, D.; Rocha, E.; Gargiulo, D.; Ramos, A. A.. "Bioactive compounds from brown seaweeds: Phloroglucinol, fucoxanthin and fucoidan as promising therapeutic agents against breast cancer". Phytochemistry Letters 14 (2015): 91-98. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000366569300017&KeyUID=WOS:000366569300017.
    10.1016/j.phytol.2015.09.007
  112. Madureira, Tania Vieira; Malhao, Fernanda; Pinheiro, Ivone; Lopes, Celia; Ferreira, Nadia; Urbatzka, Ralph; Castro, L. Filipe C.; Rocha, Eduardo. "Estrogenic and anti-estrogenic influences in cultured brown trout hepatocytes: Focus on the expression of some estrogen and peroxisomal related genes and linked phenotypic anchors". Aquatic Toxicology 169 (2015): 133-142. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000367027800014&KeyUID=WOS:000367027800014.
    10.1016/j.aquatox.2015.10.010
  113. Marques, Filipe; Vale-Costa, Silvia; Cruz, Tania; Marques, Joana Moreira; Silva, Tania; Neves, Joao Vilares; Cortes, Sofia; et al. "Studies in the mouse model identify strain variability as a major determinant of disease outcome in Leishmania infantum infection". Parasites & Vectors 8 (2015): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000367080800004&KeyUID=WOS:000367080800004.
    10.1186/s13071-015-1259-6
  114. Cunha, I.; Galante-Oliveira, S.; Rocha, E.; Urbatzka, R.; Castro, L. F. C.. "Expression of intercellular lipid transport and cholesterol metabolism genes in eggs and early larvae stages of turbot, Scophthalmus maximus, a marine aquaculture species". Marine Biology 162 8 (2015): 1673-1683. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=CCC&KeyUT=CCC:000359384600014&KeyUID=CCC:000359384600014.
  115. Ramos, Alice Abreu; Prata-Sena, Maria; Castro-Carvalho, Bruno; Dethoup, Tida; Buttachon, Suradet; Kijjoa, Anake; Rocha, Eduardo. "Potential of four marine-derived fungi extracts as anti-proliferative and cell death-inducing agents in seven human cancer cell lines". Asian Pacific Journal of Tropical Medicine 8 10 (2015): 782-790. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000363364200005&KeyUID=WOS:000363364200005.
    10.1016/j.apjtm.2015.09.005
  116. Maria L¿gia Sousa; Ana Silva; Fernanda Malh¿o; Maria Jo¿o Rocha; Eduardo Rocha; Ralph Urbatzka; Sousa ML; et al. "Reproductive hormones affect follicular cells and ooplasm of Stage I and II oocytes in zebrafish". Reprod. Fertil. Dev. (2015): http://dx.doi.org/10.1071/rd15100.
    10.1071/rd15100
  117. Urbatzka, R.; Galante-Oliveira, S.; Rocha, E.; Lobo-da-Cunha, A.; Castro, L.F.C.; Cunha, I.. "Effects of the PPARa agonist WY-14,643 on plasma lipids, enzymatic activities and mRNA expression of lipid metabolism genes in a marine flatfish, Scophthalmus maximus". Aquatic Toxicology 164 (2015): 155-162. http://www.scopus.com/inward/record.url?eid=2-s2.0-84929119141&partnerID=MN8TOARS.
    10.1016/j.aquatox.2015.05.004
  118. Santos, M.; Correia-Gomes, C.; Santos, A.; de Matos, A.; Rocha, E.; Lopes, C.; Pereira, P.D.. "Nuclear pleomorphism: Role in grading and prognosis of canine mammary carcinomas". Veterinary Journal 200 3 (2014): 426-433. http://www.scopus.com/inward/record.url?eid=2-s2.0-84901018987&partnerID=MN8TOARS.
    10.1016/j.tvjl.2014.03.019
  119. Rocha, M.J.; Cruzeiro, C.; Reis, M.; Pardal, M.Â.; Rocha, E.. "Spatial and seasonal distribution of 17 endocrine disruptor compounds in an urban estuary (Mondego River, Portugal): Evaluation of the estrogenic load of the area". Environmental Monitoring and Assessment 186 6 (2014): 3337-3350. http://www.scopus.com/inward/record.url?eid=2-s2.0-84900826715&partnerID=MN8TOARS.
    10.1007/s10661-014-3621-0
  120. Carrola, J.; Fontaínhas-Fernandes, A.; Pires, M.J.; Rocha, E.. "Frequency of hepatocellular fibrillar inclusions in European flounder (Platichthys flesus) from the Douro River estuary, Portugal". Environmental Science and Pollution Research 21 4 (2014): 3116-3125. http://www.scopus.com/inward/record.url?eid=2-s2.0-84893777349&partnerID=MN8TOARS.
    10.1007/s11356-013-2248-y
  121. Gomes, M.; Gonçalves, A.; Rocha, E.; Sá, R.; Alves, A.; Silva, J.; Barros, A.; Pereira, M.L.; Sousa, M.. "Effect of in vitro exposure to lead chloride on semen quality and sperm DNA fragmentation". Zygote (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84893698644&partnerID=MN8TOARS.
    10.1017/S0967199413000671
  122. Rocha, M.J.; Cruzeiro, C.; Peixoto, C.; Rocha, E.. "Annual Fluctuations of Endocrine-Disrupting Compounds at the Lower End of the Lima River, Portugal, and in Adjacent Coastal Waters". Archives of Environmental Contamination and Toxicology (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84903872839&partnerID=MN8TOARS.
    10.1007/s00244-014-0063-1
  123. Sousa, M.L.; Silva, A.; Malhão, F.; Rocha, M.J.; Rocha, E.; Urbatzka, R.. "Viability analysis of oocyte-follicle complexes and gonadal fragments of zebrafish as baseline for toxicity testing". Toxicology Mechanisms and Methods 24 1 (2014): 42-49. http://www.scopus.com/inward/record.url?eid=2-s2.0-84890409206&partnerID=MN8TOARS.
    10.3109/15376516.2013.846952
  124. Madureira, T.V.; Velhote, S.; Santos, C.; Cruzeiro, C.; Rocha, E.; Rocha, M.J.. "A step forward using QuEChERS (Quick, Easy, Cheap, Effective, Rugged, and Safe) based extraction and gas chromatography-tandem mass spectrometry-levels of priority polycyclic aromatic hydrocarbons in wild and commercial mussels". Environmental Science and Pollution Research 21 9 (2014): 6089-6098. http://www.scopus.com/inward/record.url?eid=2-s2.0-84899445278&partnerID=MN8TOARS.
    10.1007/s11356-014-2510-y
  125. Carrola, J.; Santos, N.; Rocha, M.J.; Fontainhas-Fernandes, A.; Pardal, M.A.; Monteiro, R.A.F.; Rocha, E.. "Frequency of micronuclei and of other nuclear abnormalities in erythrocytes of the grey mullet from the Mondego, Douro and Ave estuaries-Portugal". Environmental Science and Pollution Research 21 9 (2014): 6057-6068. http://www.scopus.com/inward/record.url?eid=2-s2.0-84899424285&partnerID=MN8TOARS.
    10.1007/s11356-014-2537-0
  126. Madureira, T.V.; Santos, C.; Velhote, S.; Cruzeiro, C.; Rocha, E.; Rocha, M.J.. "Contamination levels of polychlorinated biphenyls in wild versus cultivated samples of female and male mussels (Mytilus sp.) from the Northwest Coast of Iberian Peninsula-new application for QuEChERS (Quick, Easy, Cheap, Effective, Rugged, and Safe) methodology". Environmental Science and Pollution Research 21 2 (2014): 1528-1540. http://www.scopus.com/inward/record.url?eid=2-s2.0-84891627782&partnerID=MN8TOARS.
    10.1007/s11356-013-2017-y
  127. Castro, L.F.C.; Lobo-da-Cunha, A.; Rocha, M.J.; Urbatzka, R.; Rocha, E.. "Pex11a in brown trout (Salmo trutta f. fario): Expression dynamics during the reproductive cycle reveals sex-specific seasonal patterns". Comparative Biochemistry and Physiology - A Molecular and Integrative Physiology 164 1 (2013): 207-214. http://www.scopus.com/inward/record.url?eid=2-s2.0-84870253034&partnerID=MN8TOARS.
    10.1016/j.cbpa.2012.09.003
  128. Campos, C.; Valente, L.M.P.; Conceição, L.E.C.; Engrola, S.; Sousa, V.; Rocha, E.; Fernandes, J.M.O.. "Incubation temperature induces changes in muscle cellularity and gene expression in Senegalese sole (Solea senegalensis)". Gene 516 2 (2013): 209-217. http://www.scopus.com/inward/record.url?eid=2-s2.0-84873259378&partnerID=MN8TOARS.
    10.1016/j.gene.2012.12.074
  129. Malhão, F.; Urbatzka, R.; Navas, J.M.; Cruzeiro, C.; Monteiro, R.A.F.; Rocha, E.. "Cytological, immunocytochemical, ultrastructural and growth characterization of the rainbow trout liver cell line RTL-W1". Tissue and Cell (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84872086434&partnerID=MN8TOARS.
    10.1016/j.tice.2012.10.006
  130. Rocha, M.J.; Cruzeiro, C.; Reis, M.; Rocha, E.; Pardal, M.A.. "Determination of 17 endocrine disruptor compounds and their spatial and seasonal distribution in the Sado River Estuary (Portugal)". Toxicological and Environmental Chemistry (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84872275356&partnerID=MN8TOARS.
    10.1080/02772248.2012.758730
  131. Lima, D.; MacHado, A.; Reis-Henriques, M.A.; Rocha, E.; Santos, M.M.; Castro, L.F.C.. "Cloning and expression analysis of the 17ß hydroxysteroid dehydrogenase type 12 (HSD17B12) in the neogastropod Nucella lapillus". Journal of Steroid Biochemistry and Molecular Biology 134 1 (2013): 8-14. http://www.scopus.com/inward/record.url?eid=2-s2.0-84869145337&partnerID=MN8TOARS.
    10.1016/j.jsbmb.2012.10.005
  132. Rocha, M.J.; Cruzeiro, C.; Reis, M.; Rocha, E.; Pardal, M.. "Determination of seventeen endocrine disruptor compounds and their spatial and seasonal distribution in Ria Formosa Lagoon (Portugal)". Environmental Monitoring and Assessment 185 10 (2013): 8215-8226. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884357170&partnerID=MN8TOARS.
    10.1007/s10661-013-3168-5
  133. Rocha, M.J.; Cruzeiro, C.; Rocha, E.. "Quantification of 17 endocrine disruptor compounds and their spatial and seasonal distribution in the Iberian Ave River and its coastline". Toxicological and Environmental Chemistry 95 3 (2013): 386-399. http://www.scopus.com/inward/record.url?eid=2-s2.0-84877812692&partnerID=MN8TOARS.
    10.1080/02772248.2013.773002
  134. Almeida, C.; Correia, S.; Rocha, E.; Alves, A.; Ferraz, L.; Silva, J.; Sousa, M.; Barros, A.. "Caspase signalling pathways in human spermatogenesis". Journal of Assisted Reproduction and Genetics (2013): 1-9. http://www.scopus.com/inward/record.url?eid=2-s2.0-84873374860&partnerID=MN8TOARS.
    10.1007/s10815-013-9938-8
  135. Jordanova, M.; Rocha, M.J.; Rebok, K.; Rocha, E.. "Variations in the volumes of parenchyma and stroma of the liver and in the cytology of hepatocytes are associated with gonadal stages in female Ohrid trout (Salmo letnica)". Ichthyological Research 60 1 (2013): 26-35. http://www.scopus.com/inward/record.url?eid=2-s2.0-84872654610&partnerID=MN8TOARS.
    10.1007/s10228-012-0302-2
  136. Rocha, M.J.; Cruzeiro, C.; Rocha, E.. "Development and validation of a GC-MS method for the evaluation of 17 endocrine disruptor compounds, including phytoestrogens and sitosterol, in coastal waters - Their spatial and seasonal levels in Porto costal region (Portugal)". Journal of Water and Health 11 2 (2013): 281-296. http://www.scopus.com/inward/record.url?eid=2-s2.0-84880888850&partnerID=MN8TOARS.
    10.2166/wh.2013.021
  137. Arukwe, A.; Cangialosi, M.V.; Letcher, R.J.; Rocha, E.; Mortensen, A.S.. "Changes in morphometry and association between whole-body fatty acids and steroid hormone profiles in relation to bioaccumulation patterns in salmon larvae exposed to perfluorooctane sulfonic or perfluorooctane carboxylic acids". Aquatic Toxicology 130-131 (2013): 219-230. http://www.scopus.com/inward/record.url?eid=2-s2.0-84874372650&partnerID=MN8TOARS.
    10.1016/j.aquatox.2012.12.026
  138. Urbatzka, R.; Galante-Oliveira, S.; Rocha, E.; Castro, L.F.C.; Cunha, I.. "Normalization strategies for gene expression studies by real-time PCR in a marine fish species, Scophthalmus maximus". Marine Genomics 10 (2013): 17-25. http://www.scopus.com/inward/record.url?eid=2-s2.0-84877664667&partnerID=MN8TOARS.
    10.1016/j.margen.2013.02.001
  139. Cunha, I.; Galante-Oliveira, S.; Rocha, E.; Planas, M.; Urbatzka, R.; Castro, L.F.C.. "Dynamics of PPARs, fatty acid metabolism genes and lipid classes in eggs and early larvae of a teleost". Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology 164 4 (2013): 247-258. http://www.scopus.com/inward/record.url?eid=2-s2.0-84874439674&partnerID=MN8TOARS.
    10.1016/j.cbpb.2013.01.003
  140. Rocha, M.J.; Cruzeiro, C.; Ferreira, C.; Rocha, E.. "Occurrence of endocrine disruptor compounds in the estuary of the Iberian Douro River and nearby Porto Coast (NW Portugal)". Toxicological and Environmental Chemistry 94 2 (2012): 252-261. http://www.scopus.com/inward/record.url?eid=2-s2.0-84861142351&partnerID=MN8TOARS.
    10.1080/02772248.2011.642874
  141. Ribeiro, C.; Urbatzka, R.; Castro, L.F.C.; Carrola, J.; Fontainhas-Fernandes, A.; Monteiro, R.A.F.; Rocha, E.; Rocha, M.J.. "In vitro exposure of Nile tilapia (Oreochromis niloticus) testis to estrogenic endocrine disrupting chemicals: mRNA expression of genes encoding steroidogenic enzymes". Toxicology Mechanisms and Methods 22 1 (2012): 47-53. http://www.scopus.com/inward/record.url?eid=2-s2.0-83455166345&partnerID=MN8TOARS.
    10.3109/15376516.2011.593053
  142. Silva, P.; Rocha, M.J.; Cruzeiro, C.; Malhão, F.; Reis, B.; Urbatzka, R.; Monteiro, R.A.F.; Rocha, E.. "Testing the effects of ethinylestradiol and of an environmentally relevant mixture of xenoestrogens as found in the Douro River (Portugal) on the maturation of fish gonads-A stereological study using the zebrafish (Danio rerio) as model". Aquatic Toxicology 124-125 (2012): 1-10. http://www.scopus.com/inward/record.url?eid=2-s2.0-84864804104&partnerID=MN8TOARS.
    10.1016/j.aquatox.2012.07.002
  143. Urbatzka, R.; Galante-Oliveira, S.; Rocha, E.; Castro, L.F.C.; Cunha, I.. "Tissue expression of PPAR-alpha isoforms in Scophthalmus maximus and transcriptional response of target genes in the heart after exposure to WY-14643". Fish Physiology and Biochemistry (2012): 1-13. http://www.scopus.com/inward/record.url?eid=2-s2.0-84871399901&partnerID=MN8TOARS.
    10.1007/s10695-012-9761-7
  144. Marcos, R.; Monteiro, R.A.; Rocha, E.. "The use of design-based stereology to evaluate volumes and numbers in the liver: A review with practical guidelines". Journal of Anatomy 220 4 (2012): 303-317. http://www.scopus.com/inward/record.url?eid=2-s2.0-84858295915&partnerID=MN8TOARS.
    10.1111/j.1469-7580.2012.01475.x
  145. Santos, M.; Monteiro, R.A.F.; Rocha, E.. "A stereological study of the volume-weighted volume and of the relative volume of the nucleus of normal and preneoplastic hepatocytes in a trout model of hepatocarcinogenesis". Experimental and Toxicologic Pathology (2012): http://www.scopus.com/inward/record.url?eid=2-s2.0-84864403101&partnerID=MN8TOARS.
    10.1016/j.etp.2012.07.001
  146. Rocha, M.J.; Ribeiro, M.F.T.; Cruzeiro, C.; Figueiredo, F.; Rocha, E.. "Development and validation of a GC-MS method for determination of 39 common pesticides in estuarine water - targeting hazardous amounts in the Douro River estuary". International Journal of Environmental Analytical Chemistry 92 14 (2012): 1587-1608. http://www.scopus.com/inward/record.url?eid=2-s2.0-84867540986&partnerID=MN8TOARS.
    10.1080/03067319.2011.581366
  147. Urbatzka, R.; Rocha, E.; Reis, B.; Cruzeiro, C.; Monteiro, R.A.F.; Rocha, M.J.. "Effects of ethinylestradiol and of an environmentally relevant mixture of xenoestrogens on steroidogenic gene expression and specific transcription factors in zebrafish". Environmental Pollution 164 (2012): 28-35. http://www.scopus.com/inward/record.url?eid=2-s2.0-84856567083&partnerID=MN8TOARS.
    10.1016/j.envpol.2012.01.018
  148. Rocha, M.J.; Ribeiro, M.; Ribeiro, C.; Couto, C.; Cruzeiro, C.; Rocha, E.. "Endocrine disruptors in the Leça River and nearby Porto Coast (NW Portugal): Presence of estrogenic compounds and hypoxic conditions". Toxicological and Environmental Chemistry 94 2 (2012): 262-274. http://www.scopus.com/inward/record.url?eid=2-s2.0-84861155397&partnerID=MN8TOARS.
    10.1080/02772248.2011.644291
  149. Madureira, T.V.; Rocha, M.J.; Cruzeiro, C.; Rodrigues, I.; Monteiro, R.A.F.; Rocha, E.. "The toxicity potential of pharmaceuticals found in the Douro River estuary (Portugal): Evaluation of impacts on fish liver, by histopathology, stereology, vitellogenin and CYP1A immunohistochemistry, after sub-acute exposures of the zebrafish model". Environmental Toxicology and Pharmacology 34 1 (2012): 34-45. http://www.scopus.com/inward/record.url?eid=2-s2.0-84858725544&partnerID=MN8TOARS.
    10.1016/j.etap.2012.02.007
  150. Castro, L.F.C.; Lopes-Marques, M.; Wilson, J.M.; Rocha, E.; Reis-Henriques, M.A.; Santos, M.M.; Cunha, I.. "A novel Acetyl-CoA synthetase short-chain subfamily member 1 (Acss1) gene indicates a dynamic history of paralogue retention and loss in vertebrates". Gene 497 2 (2012): 249-255. http://www.scopus.com/inward/record.url?eid=2-s2.0-84862829496&partnerID=MN8TOARS.
    10.1016/j.gene.2012.01.013
  151. Jordanova, M.; Rocha, M.J.; Rebok, K.; Rocha, E.. "Changes in the amount of kidney pigmented macrophage aggregates throughout the breeding cycle of female Ohrid trout, Salmo letnica Kar. (Teleostei, Salmonidae)". Microscopy Research and Technique 75 2 (2012): 176-181. http://www.scopus.com/inward/record.url?eid=2-s2.0-84855996880&partnerID=MN8TOARS.
    10.1002/jemt.21040
  152. Silva, P.; Valente, L.M.P.; Olmedo, M.; ALvarez-BlaZquez, B.; Galante, M.H.; Monteiro, R.A.F.; Rocha, E.. "Influence of temperature on muscle fibre hyperplasia and hypertrophy in larvae of blackspot seabream, Pagellus bogaraveo". Aquaculture Research 42 3 (2011): 331-340. http://www.scopus.com/inward/record.url?eid=2-s2.0-79551627591&partnerID=MN8TOARS.
    10.1111/j.1365-2109.2010.02627.x
  153. Cardinal, M.; Cornet, J.; Donnay-Moreno, C.; Gouygou, J.P.; Bergé, J.P.; Rocha, E.; Soares, S.; et al. "Seasonal variation of physical, chemical and sensory characteristics of sea bream (Sparus aurata) reared under intensive conditions in Southern Europe". Food Control 22 3-4 (2011): 574-585. http://www.scopus.com/inward/record.url?eid=2-s2.0-78649805233&partnerID=MN8TOARS.
    10.1016/j.foodcont.2010.10.007
  154. Madureira, T.V.; Cruzeiro, C.; Rocha, M.J.; Rocha, E.. "The toxicity potential of pharmaceuticals found in the Douro River estuary (Portugal)-Experimental assessment using a zebrafish embryo test". Environmental Toxicology and Pharmacology 32 2 (2011): 212-217. http://www.scopus.com/inward/record.url?eid=2-s2.0-80051586550&partnerID=MN8TOARS.
    10.1016/j.etap.2011.05.005
  155. Madureira, T.V.; Rocha, M.J.; Cruzeiro, C.; Galante, M.H.; Monteiro, R.A.F.; Rocha, E.. "The toxicity potential of pharmaceuticals found in the Douro River estuary (Portugal): Assessing impacts on gonadal maturation with a histopathological and stereological study of zebrafish ovary and testis after sub-acute exposures". Aquatic Toxicology 105 3-4 (2011): 292-299. http://www.scopus.com/inward/record.url?eid=2-s2.0-79960465071&partnerID=MN8TOARS.
    10.1016/j.aquatox.2011.06.017
  156. Castro, L.F.C.; Wilson, J.M.; Gonçalves, O.; Galante-Oliveira, S.; Rocha, E.; Cunha, I.. "The evolutionary history of the stearoyl-CoA desaturase gene family in vertebrates". BMC Evolutionary Biology 11 1 (2011): http://www.scopus.com/inward/record.url?eid=2-s2.0-79956002928&partnerID=MN8TOARS.
    10.1186/1471-2148-11-132
  157. Urbatzka, R.; Rocha, M.J.; Rocha, E.. "Regulation of Ovarian Development and Function in Teleosts". Hormones and Reproduction of Vertebrates - Volume 1 1 1st (2011): 65-82. http://www.scopus.com/inward/record.url?eid=2-s2.0-79958259773&partnerID=MN8TOARS.
    Publicado • 10.1016/B978-0-12-375009-9.10004-9
  158. Rocha, M.J.; Ferreira, P.C.; Reis, P.A.; Cruzeiro, C.; Rocha, E.. "Determination of polycyclic aromatic hydrocarbons in coastal sediments from the porto region (Portugal) by microwave-assisted extraction, followed by SPME and GC-MS". Journal of Chromatographic Science 49 9 (2011): 695-701. http://www.scopus.com/inward/record.url?eid=2-s2.0-80455129120&partnerID=MN8TOARS.
  159. Valente, L.M.P.; Cornet, J.; Donnay-Moreno, C.; Gouygou, J.P.; Bergé, J.P.; Bacelar, M.; Escórcio, C.; et al. "Quality differences of gilthead sea bream from distinct production systems in Southern Europe: Intensive, integrated, semi-intensive or extensive systems". Food Control 22 5 (2011): 708-717. http://www.scopus.com/inward/record.url?eid=2-s2.0-78650299368&partnerID=MN8TOARS.
    10.1016/j.foodcont.2010.11.001
  160. Madureira, T.V.; Barreiro, J.C.; Rocha, M.J.; Rocha, E.; Cass, Q.B.; Tiritan, M.E.. "Spatiotemporal distribution of pharmaceuticals in the Douro River estuary (Portugal)". Science of the Total Environment 408 22 (2010): 5513-5520. http://www.scopus.com/inward/record.url?eid=2-s2.0-77956882358&partnerID=MN8TOARS.
    10.1016/j.scitotenv.2010.07.069
  161. Rocha, E.; Rocha, M.J.; Lobo-Da-Cunha, A.; Galante, M.H.; Monteiro, R.A.F.. "The hepatocytes of the brown trout (Salmo trutta fario): A stereological study of some cytoplasmic components with the breeding cycle". Microscopy Research and Technique 73 8 (2010): 766-778. http://www.scopus.com/inward/record.url?eid=2-s2.0-77956153830&partnerID=MN8TOARS.
    10.1002/jemt.20820
  162. Resende, A.D.; Lobo-Da-Cunha, A.; Malho, F.; Franquinho, F.; Monteiro, R.A.F.; Rocha, E.. "Histological and stereological characterization of brown trout (Salmo trutta f. fario) trunk kidney". Microscopy and Microanalysis 16 6 (2010): 677-687. http://www.scopus.com/inward/record.url?eid=2-s2.0-79451472204&partnerID=MN8TOARS.
    10.1017/S1431927610093918
  163. Silva, P.; Power, D.M.; Valente, L.M.P.; Silva, N.; Monteiro, R.A.F.; Rocha, E.. "Expression of the myosin light chains 1, 2 and 3 in the muscle of blackspot seabream (Pagellus bogaraveo, Brunnich), during development". Fish Physiology and Biochemistry 36 4 (2010): 1125-1132. http://www.scopus.com/inward/record.url?eid=2-s2.0-78149478810&partnerID=MN8TOARS.
    10.1007/s10695-010-9390-y
  164. Silva, P.; Valente, L.M.P.; Olmedo, M.; Galante, M.H.; Monteiro, R.A.F.; Rocha, E.. "Hyperplastic and hypertrophic growth of lateral muscle in blackspot seabream Pagellus bogaraveo from hatching to juvenile". Journal of Fish Biology 74 1 (2009): 37-53. http://www.scopus.com/inward/record.url?eid=2-s2.0-58549106408&partnerID=MN8TOARS.
    10.1111/j.1095-8649.2008.02122.x
  165. Carrola, J.; Fontaínhas-Fernandes, A.; Matos, P.; Rocha, E.. "Liver histopathology in brown trout (salmo trutta f. fario) from the tinhela river, subjected to mine drainage from the abandoned jales mine (Portugal)". Bulletin of Environmental Contamination and Toxicology 83 1 (2009): 35-41. http://www.scopus.com/inward/record.url?eid=2-s2.0-67349224991&partnerID=MN8TOARS.
    10.1007/s00128-009-9726-4
  166. Ribeiro, C.; Tiritan, M.E.; Rocha, E.; Rocha, M.J.. "Seasonal and spatial distribution of several endocrine-disrupting compounds in the Douro River estuary, Portugal". Archives of Environmental Contamination and Toxicology 56 1 (2009): 1-11. http://www.scopus.com/inward/record.url?eid=2-s2.0-58149091855&partnerID=MN8TOARS.
    10.1007/s00244-008-9158-x
  167. Kortner, T.M.; Rocha, E.; Arukwe, A.. "Previtellogenic oocyte growth and transcriptional changes of steroidogenic enzyme genes in immature female Atlantic cod (Gadus morhua L.) after exposure to the androgens 11-ketotestosterone and testosterone". Comparative Biochemistry and Physiology - A Molecular and Integrative Physiology 152 3 (2009): 304-313. http://www.scopus.com/inward/record.url?eid=2-s2.0-61349202132&partnerID=MN8TOARS.
    10.1016/j.cbpa.2008.11.001
  168. Batista-Pinto, C.; Rocha, E.; Castro, L.F.C.; Rodrigues, P.; Lobo-da-Cunha, A.. "Seasonal and gender variation of peroxisome proliferator activated receptors expression in brown trout liver". General and Comparative Endocrinology 161 1 (2009): 146-152. http://www.scopus.com/inward/record.url?eid=2-s2.0-60749117732&partnerID=MN8TOARS.
    10.1016/j.ygcen.2008.11.019
  169. Rocha, E.; Rocha, M.J.; Galante, M.H.; Silva, M.W.; Monteiro, R.A.F.. "The hepatocytes of the brown trout (Salmo trutta f. fario): A stereological study of their number and size during the breeding cycle". Ichthyological Research 56 1 (2009): 43-54. http://www.scopus.com/inward/record.url?eid=2-s2.0-59149091872&partnerID=MN8TOARS.
    10.1007/s10228-008-0066-x
  170. Castro, L.F.C.; Rocha, M.J.; Lobo-da-Cunha, A.; Batista-Pinto, C.; Machado, A.; Rocha, E.. "The 17ß-hydroxysteroid dehydrogenase 4: Gender-specific and seasonal gene expression in the liver of brown trout (Salmo trutta f. fario)". Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology 153 2 (2009): 157-164. http://www.scopus.com/inward/record.url?eid=2-s2.0-66949137818&partnerID=MN8TOARS.
    10.1016/j.cbpb.2009.02.015
  171. Marcos, R.; Santos, M.; Santos, N.; Malhão, F.; Ferreira, F.; Monteiro, R.A.F.; Rocha, E.. "Use of destained cytology slides for the application of routine special stains". Veterinary Clinical Pathology 38 1 (2009): 94-102. http://www.scopus.com/inward/record.url?eid=2-s2.0-67549102931&partnerID=MN8TOARS.
    10.1111/j.1939-165X.2008.00098.x
  172. Kortner, T.M.; Rocha, E.; Arukwe, A.. "Androgenic modulation of early growth of Atlantic cod (Gadus morhua L.) previtellogenic oocytes and zona radiata-related genes". Journal of Toxicology and Environmental Health - Part A: Current Issues 72 3-4 (2009): 184-195. http://www.scopus.com/inward/record.url?eid=2-s2.0-60749105733&partnerID=MN8TOARS.
    10.1080/15287390802539020
  173. Monteiro, S.M.; Rocha, E.; Mancera, J.M.; Fontaínhas-Fernandes, A.; Sousa, M.. "A stereological study of copper toxicity in gills of Oreochromis niloticus". Ecotoxicology and Environmental Safety 72 1 (2009): 213-223. http://www.scopus.com/inward/record.url?eid=2-s2.0-54049146283&partnerID=MN8TOARS.
    10.1016/j.ecoenv.2008.02.008
  174. Silva, P.; Valente, L.M.P.; Galante, M.H.; Andrade, C.A.P.; Monteiro, R.A.F.; Rocha, E.. "Dietary protein content influences both growth and size distribution of anterior and posterior muscle fibres in juveniles of Pagellus bogaraveo (Brunnich)". Journal of Muscle Research and Cell Motility 30 1-2 (2009): 29-39. http://www.scopus.com/inward/record.url?eid=2-s2.0-67349281253&partnerID=MN8TOARS.
    10.1007/s10974-009-9167-z
  175. Ribeiro, C.; Pardal, M.Â.; Tiritan, M.E.; Rocha, E.; Margalho, R.M.; Rocha, M.J.. "Spatial distribution and quantification of endocrine-disrupting chemicals in Sado River estuary, Portugal". Environmental Monitoring and Assessment 159 1-4 (2009): 415-427. http://www.scopus.com/inward/record.url?eid=2-s2.0-70450231936&partnerID=MN8TOARS.
    10.1007/s10661-008-0639-1
  176. Ribeiro, C.; Pardal, M.Â.; Martinho, F.; Margalho, R.; Tiritan, M.E.; Rocha, E.; Rocha, M.J.. "Distribution of endocrine disruptors in the Mondego River estuary, Portugal". Environmental Monitoring and Assessment 149 1-4 (2009): 183-193. http://www.scopus.com/inward/record.url?eid=2-s2.0-58549091683&partnerID=MN8TOARS.
    10.1007/s10661-008-0192-y
  177. Jordanova, M.; Miteva, N.; Santos, N.; Malhão, F.; Rocha, E.. "Crystalline inclusions in hepatocytes and associated interhepatocytic macrophages from female Ohrid trout (Salmo letnica Kar.)". Tissue and Cell 41 4 (2009): 281-285. http://www.scopus.com/inward/record.url?eid=2-s2.0-67649908903&partnerID=MN8TOARS.
    10.1016/j.tice.2008.12.005
  178. Santos, M.; Marcos, R.; Santos, N.; Malhão, F.; Monteiro, R.A.F.; Rocha, E.. "An unbiased stereological study on subpopulations of rat liver macrophages and on their numerical relation with the hepatocytes and stellate cells". Journal of Anatomy 214 5 (2009): 744-751. http://www.scopus.com/inward/record.url?eid=2-s2.0-65449128453&partnerID=MN8TOARS.
    10.1111/j.1469-7580.2009.01055.x
  179. Fernandes, C.; Fontaínhas-Fernandes, A.; Rocha, E.; Salgado, M.A.. "Monitoring pollution in Esmoriz-Paramos lagoon, Portugal: Liver histological and biochemical effects in Liza saliens". Environmental Monitoring and Assessment 145 1-3 (2008): 315-322. http://www.scopus.com/inward/record.url?eid=2-s2.0-51749094657&partnerID=MN8TOARS.
    10.1007/s10661-007-0041-4
  180. Silva, P.; Rowlerson, A.M.; Valente, L.M.P.; Olmedo, M.; Monteiro, R.A.F.; Rocha, E.. "Muscle differentiation in blackspot seabream (Pagellus bogaraveo, Brunnich): Histochemical and immunohistochemical study of the fibre types". Tissue and Cell 40 6 (2008): 447-458. http://www.scopus.com/inward/record.url?eid=2-s2.0-54249092335&partnerID=MN8TOARS.
    10.1016/j.tice.2008.05.001
  181. Luís, A.; Rocha, E.; Oliveira, E.; Silva, J.; Barros, A.; Sousa, M.. "Stereological analysis of mitochondria and smooth endoplasmic reticulum distribution in human oocytes at prophase i". Microscopy and Microanalysis 14 SUPPL. 3 (2008): 103-104. http://www.scopus.com/inward/record.url?eid=2-s2.0-53349161051&partnerID=MN8TOARS.
    10.1017/S1431927608089538
  182. Monteiro, S.M.; Rocha, E.; Fontaínhas-Fernandes, A.; Sousa, M.. "Quantitative histopathology of Oreochromis niloticus gills after copper exposure". Journal of Fish Biology 73 6 (2008): 1376-1392. http://www.scopus.com/inward/record.url?eid=2-s2.0-53549087768&partnerID=MN8TOARS.
    10.1111/j.1095-8649.2008.02009.x
  183. Kortner, T.M.; Rocha, E.; Silva, P.; Castro, L.F.C.; Arukwe, A.. "Genomic approach in evaluating the role of androgens on the growth of Atlantic cod (Gadus morhua) previtellogenic oocytes". Comparative Biochemistry and Physiology - Part D: Genomics and Proteomics 3 3 (2008): 205-218. http://www.scopus.com/inward/record.url?eid=2-s2.0-47849111881&partnerID=MN8TOARS.
    10.1016/j.cbd.2008.04.001
  184. Jordanova, M.; Miteva, N.; Rocha, E.. "A qualitative and quantitative study of the hepatic pigmented macrophage aggregates during the breeding cycle of ohrid trout, Salmo letnica Kar. (Teloestei, Salmonidae)". Microscopy Research and Technique 71 11 (2008): 822-830. http://www.scopus.com/inward/record.url?eid=2-s2.0-55849093180&partnerID=MN8TOARS.
    10.1002/jemt.20626
  185. Diniz, C.; Leal, S.; Logan, K.; Rocha-Pereira, C.; Soares, A.S.; Rocha, E.; Gonçalves, J.; Fresco, P.. "Immunohistochemical localization of angiotensin II receptor types 1 and 2 in the mesenteric artery from spontaneously hypertensive rats". Microscopy Research and Technique 70 8 (2007): 677-681. http://www.scopus.com/inward/record.url?eid=2-s2.0-34547917136&partnerID=MN8TOARS.
    10.1002/jemt.20453
  186. Figueiredo-Fernandes, A.M.; Fontaínhas-Fernandes, A.A.; Monteiro, R.A.F.; Reis-Henriques, M.A.; Rocha, E.. "Spatial relationships of the intrahepatic vascular-biliary tracts and associated pancreatic acini of Nile tilapia, Oreochromis niloticus (Teleostei, Cichlidae): A serial section study by light microscopy". Annals of Anatomy 189 1 (2007): 17-30. http://www.scopus.com/inward/record.url?eid=2-s2.0-33846071168&partnerID=MN8TOARS.
    10.1016/j.aanat.2006.06.009
  187. Silva, P.; Rocha, E.; Olmedo, M.; Álvarez-Blázquez, B.; Galante, M.H.; Valente, L.M.P.. "Temperature effects on muscle fibres number at hatch and first feeding in blackspot seabream (Pagellus bogaraveo)". Archiv fur Tierzucht 50 SPEC. ISS. (2007): 06-07. http://www.scopus.com/inward/record.url?eid=2-s2.0-34547258868&partnerID=MN8TOARS.
  188. Jordanova, M.; Miteva, N.; Rocha, E.. "A quantitative study of the hepatic eosinophilic granule cells and rodlet cells during the breeding cycle of Ohrid trout, Salmo letnica Kar. (Teloestei, Salmonidae)". Fish and Shellfish Immunology 23 2 (2007): 473-478. http://www.scopus.com/inward/record.url?eid=2-s2.0-34248400724&partnerID=MN8TOARS.
    10.1016/j.fsi.2006.11.004
  189. Marcos, R.; Monteiro, R.A.F.; Rocha, E.. "Determination of hepatocellularity number in the rat". Toxicology in Vitro 21 8 (2007): 1692-1693. http://www.scopus.com/inward/record.url?eid=2-s2.0-36048940086&partnerID=MN8TOARS.
    10.1016/j.tiv.2007.09.006
  190. Ribeiro, C.; Tiritan, M.E.; Rocha, E.; Rocha, M.J.. "Development and validation of a HPLC-DAD method for determination of several endocrine disrupting compounds in estuarine water". Journal of Liquid Chromatography and Related Technologies 30 18 (2007): 2729-2746. http://www.scopus.com/inward/record.url?eid=2-s2.0-34548074182&partnerID=MN8TOARS.
    10.1080/10826070701560652
  191. Matos, P.; Fontaínhas-Fernandes, A.; Peixoto, F.; Carrola, J.; Rocha, E.. "Biochemical and histological hepatic changes of Nile tilapia Oreochromis niloticus exposed to carbaryl". Pesticide Biochemistry and Physiology 89 1 (2007): 73-80. http://www.scopus.com/inward/record.url?eid=2-s2.0-34447542742&partnerID=MN8TOARS.
    10.1016/j.pestbp.2007.03.002
  192. Figueiredo-Fernandes, A.M.; Fontaínhas-Fernandes, A.A.; Monteiro, R.A.F.; Reis-Henriques, M.A.; Rocha, E.. "Temperature and gender influences on the hepatic stroma (and associated pancreatic acini) of Nile tilapia, Oreochromis niloticus (Teleostei, Cichlidae): A stereological analysis by light microscopy". Journal of Morphology 267 2 (2006): 221-230. http://www.scopus.com/inward/record.url?eid=2-s2.0-33644860150&partnerID=MN8TOARS.
    10.1002/jmor.10396
  193. Figueiredo-Fernandes, A.; Fontaínhas-Fernandes, A.; Rocha, E.; Reis-Henriques, M.A.. "The effect of paraquat on hepatic EROD activity, liver, and gonadal histology in males and females of Nile tilapia, Oreochromis niloticus, exposed at different temperatures". Archives of Environmental Contamination and Toxicology 51 4 (2006): 626-632. http://www.scopus.com/inward/record.url?eid=2-s2.0-33750055531&partnerID=MN8TOARS.
    10.1007/s00244-005-0208-3
  194. Marcos, R.; Santos, M.; Marrinhas, C.; Rocha, E.. "Cutaneous transmissible venereal tumor without genital involvement in a prepubertal female dog". Veterinary Clinical Pathology 35 1 (2006): 106-109. http://www.scopus.com/inward/record.url?eid=2-s2.0-33645794295&partnerID=MN8TOARS.
    10.1111/j.1939-165X.2006.tb00097.x
  195. Chatchavalvanich, K.; Marcos, R.; Poonpirom, J.; Thongpan, A.; Rocha, E.. "Histology of the digestive tract of the freshwater stingray Himantura signifer Compagno and Roberts, 1982 (Elasmobranchii, Dasyatidae)". Anatomy and Embryology 211 5 (2006): 507-518. http://www.scopus.com/inward/record.url?eid=2-s2.0-33749258607&partnerID=MN8TOARS.
    10.1007/s00429-006-0103-3
  196. Figueiredo-Fernandes, A.; Fontaínhas-Fernandes, A.; Peixoto, F.; Rocha, E.; Reis-Henriques, M.A.. "Effects of gender and temperature on oxidative stress enzymes in Nile tilapia Oreochromis niloticus exposed to paraquat". Pesticide Biochemistry and Physiology 85 2 (2006): 97-103. http://www.scopus.com/inward/record.url?eid=2-s2.0-33747762330&partnerID=MN8TOARS.
    10.1016/j.pestbp.2005.11.001
  197. Figueiredo-Fernandes, A.; Fontaínhas-Fernandes, A.; Monteiro, R.; Reis-Henriques, M.A.; Rocha, E.. "Effects of the fungicide mancozeb on liver structure of Nile tilapia, Oreochromis niloticus: Assessment and quantification of induced cytological changes using qualitative histopathology and the stereological point-sampled intercept method". Bulletin of Environmental Contamination and Toxicology 76 2 (2006): 249-255. http://www.scopus.com/inward/record.url?eid=2-s2.0-32344440082&partnerID=MN8TOARS.
    10.1007/s00128-006-0914-1
  198. Marcos, R.; Monteiro, R.A.F.; Rocha, E.. "Design-based stereological estimation of hepatocyte number, by combining the smooth optical fractionator and immunocytochemistry with anti-carcinoembryonic antigen polyclonal antibodies". Liver International 26 1 (2006): 116-124. http://www.scopus.com/inward/record.url?eid=2-s2.0-33645978405&partnerID=MN8TOARS.
    10.1111/j.1478-3231.2005.01201.x
  199. Silva, P.; Andrade, C.A.P.; Timóteo, V.M.F.A.; Rocha, E.; Valente, L.M.P.. "Dietary protein, growth, nutrient utilization and body composition of juvenile blackspot seabream, Pagellus bogaraveo (Brunnich)". Aquaculture Research 37 10 (2006): 1007-1014. http://www.scopus.com/inward/record.url?eid=2-s2.0-33745811332&partnerID=MN8TOARS.
    10.1111/j.1365-2109.2006.01520.x
  200. Marcos, R.; Santos, M.; Oliveira, J.; Vieira, M.J.; Vieira, A.L.; Rocha, E.. "Cytochemical detection of calcium in a case of calcinosis circumscripta in a dog". Veterinary Clinical Pathology 35 2 (2006): 239-242. http://www.scopus.com/inward/record.url?eid=2-s2.0-33745646336&partnerID=MN8TOARS.
    10.1111/j.1939-165X.2006.tb00122.x
  201. Rowlerson, A.M.; Silva, P.; Rocha, E.; Olmedo, M.; Valente, L.M.P.. "Muscle development in cultured blackspot seabream Pagellus bogaraveo: Preliminary histochemical and immunohistochemical data on the fibre types". Archiv fur Tierzucht 48 SPEC. ISS. (2005): http://www.scopus.com/inward/record.url?eid=2-s2.0-18244408581&partnerID=MN8TOARS.
  202. Batista-Pinto, C.; Rodrigues, P.; Rocha, E.; Lobo-da-Cunha, A.. "Identification and organ expression of peroxisome proliferator activated receptors in brown trout (Salmo trutta f. fario)". Biochimica et Biophysica Acta - Gene Structure and Expression 1731 2 (2005): 88-94. http://www.scopus.com/inward/record.url?eid=2-s2.0-28344457843&partnerID=MN8TOARS.
    10.1016/j.bbaexp.2005.09.001
  203. Monteiro, R.A.F.; Henrique, R.M.F.; Oliveira, M.H.; Silva, M.W.; Rocha, E.. "Postnatal cerebellar granule cells of the white rat (Rattus norvegicus): A quantitative study, using design-based stereology". Annals of Anatomy 187 2 (2005): 161-173. http://www.scopus.com/inward/record.url?eid=2-s2.0-21244442943&partnerID=MN8TOARS.
    10.1016/j.aanat.2004.08.009
  204. Figueiredo-Silva, A.; Rocha, E.; Dias, J.; Silva, P.; Rema, P.; Gomes, E.; Valente, L.M.P.. "Partial replacement of fish oil by soybean oil on lipid distribution and liver histology in European sea bass (Dicentrarchus labrax) and rainbow trout (Oncorhynchus mykiss) juveniles". Aquaculture Nutrition 11 2 (2005): 147-155. http://www.scopus.com/inward/record.url?eid=2-s2.0-15944427864&partnerID=MN8TOARS.
    10.1111/j.1365-2095.2004.00337.x
  205. Calado, A.M.; Rocha, E.; Colaço, A.; Sousa, M.. "Comparative stereological study of cumulus-oocyte complexes aspirated from follicles during the estrous cycle in bovine | Estudo estereológico comparative de complexes cumulus-ovócito aspirados de folículos durante o ciclo estral em bovinos". Arquivo Brasileiro de Medicina Veterinaria e Zootecnia 57 4 (2005): 465-475. http://www.scopus.com/inward/record.url?eid=2-s2.0-31544433939&partnerID=MN8TOARS.
  206. Figueiredo-Silva, A.; Rocha, E.; Dias, J.; Silva, P.; Rema, P.; Gomes, E.; Valente, L.M.P.. "Erratum: (Aquaculture Nutrition (2005) 11 (147-155))". Aquaculture Nutrition 11 3 (2005): http://www.scopus.com/inward/record.url?eid=2-s2.0-21144459410&partnerID=MN8TOARS.
    10.1111/j.1365-2095.2005.00350.x
  207. Resende, A.D.; Rocha, E.; Lobo-Da-Cunha, A.. "Activity of purine catabolism enzymes during the reproductive cycle of male and female brown trout (Salmo trutta)". Annals of the New York Academy of Sciences 1040 (2005): 444-447. http://www.scopus.com/inward/record.url?eid=2-s2.0-22144471523&partnerID=MN8TOARS.
    10.1196/annals.1327.085
  208. Marcos, R.; Monteiro, R.A.F.; Rocha, E.. "Estimation of the number of stellate cells in a liver with the smooth fractionator". Journal of Microscopy 215 2 (2004): 174-182. http://www.scopus.com/inward/record.url?eid=2-s2.0-4344695230&partnerID=MN8TOARS.
    10.1111/j.0022-2720.2004.01366.x
  209. Calado, A.M.; Rocha, E.; Colaço, A.; Sousa, M.. "Stereological characterization of bovine (Bos taurus) cumulus-oocyte complexes aspirated from small antral follicles during the metestrous and proestrous phases". Theriogenology 60 3 (2003): 429-443. http://www.scopus.com/inward/record.url?eid=2-s2.0-0038420944&partnerID=MN8TOARS.
    10.1016/S0093-691X(03)00038-4
  210. Calado, A.M.; Rocha, E.; Colaço, A.; Sousa, M.. "A stereological study of medium antral follicles during the bovine estrous cycle". Tissue and Cell 35 5 (2003): 313-323. http://www.scopus.com/inward/record.url?eid=2-s2.0-0142063419&partnerID=MN8TOARS.
    10.1016/S0040-8166(03)00053-3
  211. Marcos, R.; Rocha, E.; Henrique, R.M.F.; Monteiro, R.A.F.. "A new approach to an unbiased estimate of the hepatic stellate cell index in the rat liver: An example in healthy conditions". Journal of Histochemistry and Cytochemistry 51 8 (2003): 1101-1104. http://www.scopus.com/inward/record.url?eid=2-s2.0-0042745504&partnerID=MN8TOARS.
  212. Rocha, M.J.; Rocha, E.; Resende, A.D.; Lobo-Da-Cunha, A.. "Measurement of peroxisomal enzyme activities in the liver of brown trout (Salmo trutta), using spectrophotometric methods". BMC Biochemistry 4 (2003): 1-9. http://www.scopus.com/inward/record.url?eid=2-s2.0-2942648552&partnerID=MN8TOARS.
    10.1186/1471-2091-4-1
  213. Resende, A.D.; Rocha, E.; Monteiro, R.A.F.; Rodrigues, P.. "The interhepatocytic macrophages and pale-grey cells in brown trout liver ontogenesis". Journal of Fish Biology 60 6 (2002): 1381-1390. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036622460&partnerID=MN8TOARS.
    10.1006/jfbi.2002.1916
  214. Rocha, E.; Monteiro, R.A.F.; Oliveira, M.H.; Silva, M.W.. "The hepatocytes of the brown trout (Salmo trutta f. fario): A quantitative study using design-based stereology". Histology and Histopathology 16 2 (2001): 423-437. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035072962&partnerID=MN8TOARS.
  215. Henrique, R.M.F.; Rocha, E.; Reis, A.; Marcos, R.; Oliveira, M.H.; Silva, M.W.; Monteiro, R.A.F.. "Age-related changes in rat cerebellar basket cells: A quantitative study using unbiased stereological methods". Journal of Anatomy 198 6 (2001): 727-736. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034939426&partnerID=MN8TOARS.
    10.1017/S002187820100783X
  216. Calado, A.M.; Rocha, E.; Colaço, A.; Sousa, M.. "Stereologic characterization of bovine (Bos taurus) cumulus-oocyte complexes aspirated from small antral follicles during the diestrous phase". Biology of Reproduction 65 5 (2001): 1383-1391. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034763916&partnerID=MN8TOARS.
  217. Marcos, R.; Rocha, E.; Monteiro, R.A.F.. "Strategies to maximize adhesion of thick paraffin sections of the brown trout liver for stereological purposes". Journal of Histotechnology 24 1 (2001): 37-42. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035071737&partnerID=MN8TOARS.
  218. Monteiro, R.A.F.; Henrique, R.M.F.; Rocha, E.; Silva, M.W.; Oliveira, M.H.. "Quantitative age-changes in endoplasmic reticulum and nucleus of cerebellar granule cells". Neurobiology of Aging 21 1 (2000): 97-105. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034594435&partnerID=MN8TOARS.
    10.1016/S0197-4580(00)00104-4
  219. Valente, L.M.P.; Rocha, E.; Gomes, E.F.S.; Silva, M.W.; Oliveira, M.H.; Monteiro, R.A.F.; Fauconneau, B.. "Growth dynamics of white and red muscle fibres in fast- and slow-growing strains of rainbow trout". Journal of Fish Biology 55 4 (1999): 675-691. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033212824&partnerID=MN8TOARS.
    10.1006/jfbi.1999.1027
  220. Rocha, E.; Lobo-Da-Cunha, A.; Monteiro, R.A.F.; Silva, M.W.; Oliveira, M.H.. "A stereological study along the year on the hepatocytic peroxisomes of brown trout (Salmo trutta)". Journal of Submicroscopic Cytology and Pathology 31 1 (1999): 91-105. http://www.scopus.com/inward/record.url?eid=2-s2.0-0000542183&partnerID=MN8TOARS.
  221. Monteiro, R.A.F.; Henrique, R.M.F.; Rocha, E.; Marini-Abreu, M.M.; Oliveira, M.H.; Silva, M.W.. "Age-related changes in the volume of somata and organelles of cerebellar granule cells". Neurobiology of Aging 19 4 (1998): 325-332. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031705468&partnerID=MN8TOARS.
    10.1016/S0197-4580(98)00064-5
  222. Barros A; Sousa M; Silva J; Almeida V; Rocha E. "Aging, hyaluronidase removal of the cumulus, and microinjection do not affect the sperm binding potential of human oocytes.". Journal of assisted reproduction and genetics (1997): http://europepmc.org/abstract/med/9048240.
    10.1007/BF02765778
  223. Henrique, R.M.F.; Monteiro, R.A.F.; Rocha, E.; Marini-Abreu, M.M.. "A stereological study on the nuclear volume of cerebellar granule cells in aging rats". Neurobiology of Aging 18 2 (1997): 199-203. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030740958&partnerID=MN8TOARS.
    10.1016/S0197-4580(97)00006-7
  224. Rocha, E.; Monteiro, R.A.F.; Pereira, C.A.. "Liver of the brown trout, Salmo trutta (Teleostei, Salmonidae): A stereological study at light and electron microscopic levels". Anatomical Record 247 3 (1997): 317-328. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031053960&partnerID=MN8TOARS.
    10.1002/(SICI)1097-0185(199703)247:3<317::AID-AR3>3.0.CO;2-R
  225. Rocha, E.; Monteiro, R.A.F.; Pereira, C.A.. "The pale-grey interhepatocytic cells of brown trout (Salmo trutta) are a subpopulation of liver resident macrophages or do they establish a different cellular type?". Journal of Submicroscopic Cytology and Pathology 28 3 (1996): 357-368. http://www.scopus.com/inward/record.url?eid=2-s2.0-0000918588&partnerID=MN8TOARS.
  226. Monteiro, R.A.F.; Rocha, E.; Marini-Abreu, M.M.. "Do microglia arise from pericytes? An ultrastructural and distribution study in the rat cerebellar cortex". Journal of Submicroscopic Cytology and Pathology 28 4 (1996): 457-469. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030253528&partnerID=MN8TOARS.
  227. Monteiro, R.A.F.; Conceicao, L.E.C.; Rocha, E.; Marini-Abreu, M.M.. "Age changes in cerebellar oligodendrocytes: The appearance of nuclear filaments and increase in the volume density of the nucleus and in the number of dark cell forms". Archives of Histology and Cytology 58 4 (1995): 417-425. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028810336&partnerID=MN8TOARS.
  228. Rocha, E.; Monteiro, R.A.F.; Pereira, C.A.. "The liver of the brown trout, Salmo trutta fario: A light and electron microscope study". Journal of Anatomy 185 2 (1994): 241-249. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028142184&partnerID=MN8TOARS.
  229. Monteiro, R.A.F.; Rocha, E.; Marini-Abreu, M.M.. "Heterogeneity and death of Purkinje cells of rat neocerebellum (Crus I and Crus II): Hypothetic mechanisms based on qualitative and quantitative microscopical data". Journal of Brain Research 35 2 (1994): 205-222. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028342780&partnerID=MN8TOARS.
  230. Monteiro, R.A.F.; Rocha, E.; Marini-Abreu, M.M.. "Quantitative age-related changes on nuclear invaginations of neocerebellar Purkinje cells". NeuroReport 3 12 (1992): 1089-1092. http://www.scopus.com/inward/record.url?eid=2-s2.0-0027076695&partnerID=MN8TOARS.
  231. Rocha, E.; Monteiro, R.A.. "Ultrastructural qualitative and quantitative data on the sporogenesis of the protozoan Abelspora portucalensis (Microspora, Abelsporidae): a different approach to the study of microsporidia.". Journal of Morphology 213 3 (1992): 295-303. http://www.scopus.com/inward/record.url?eid=2-s2.0-0026912751&partnerID=MN8TOARS.
  232. Monteiro, R.A.F.; Rocha, E.; Marini-Abreu, M.M.. "Age-related morphometric changes occurring in the somata of astrocytes of the granular layer of rat neocerebellar cortex (Crus I and Crus II)". Histology and Histopathology 7 3 (1992): 427-444. http://www.scopus.com/inward/record.url?eid=2-s2.0-0026700346&partnerID=MN8TOARS.
  233. Monteiro, R.A.; Rocha, E.; Marini-Abreu, M.M.. "Age-related quantitative changes in inhibitory axo-somatic synapses on Purkinje cells of rat neocerebellum (Crus I and Crus II).". Journal of submicroscopic cytology and pathology 24 3 (1992): 351-357. http://www.scopus.com/inward/record.url?eid=2-s2.0-0026889436&partnerID=MN8TOARS.
  234. Monteiro, R.A.F.; Rocha, E.. "Are Ranvier's nodes of the central nervous system also artifacts by preparation?". Acta Anatomica 145 2 (1992): 179-180. http://www.scopus.com/inward/record.url?eid=2-s2.0-0026697837&partnerID=MN8TOARS.
  235. EDUARDO ROCHA; CARLOS AZEVEDO. "Ultrastructural study of the spermatogenesis of Anodonta cygnea L. (Bivalvia, Unionidae)". Invertebrate Reproduction & Development 18 3 (1990): 169-176. http://dx.doi.org/10.1080/07924259.1990.9672140.
    10.1080/07924259.1990.9672140
Capítulo de livro
  1. Maria João Rocha; Rocha, Eduardo. "The diversity of reproductive styles exhibited by fish.". In Encyclopedia of Fish Physiology, editado por Sarah L. Alderman; Todd E. Gillis. Elsevier, 2024.
    Publicado
  2. Cruzeiro, Catarina; Rocha, Eduardo; Rocha, Maria João. "Pesticides in Worldwide Aquatic Systems: Part I". In Estuary. InTech, 2018.
    10.5772/intechopen.71644
  3. Rocha, Eduardo. "Pesticides in Worldwide Aquatic Systems: Part II". 2018.
    10.5772/66262
  4. Rocha, Maria João; Rocha, Eduardo. "Estrogenic Compounds in Estuarine and Coastal Water Environments of the Iberian Western Atlantic Coast and Selected Locations Worldwide — Relevancy, Trends and Challenges in View of the EU Water Framework Directive". In Toxicology Studies - Cells, Drugs and Environment. InTech, 2015.
    10.5772/59885
  5. Urbatzka, R.; Rocha, M.J.; Rocha, E.. "Regulation of ovarian development and function in teleosts". In Hormones and Reproduction of Vertebrates, Volume 1, editado por David O. Norris and Kristin H. Lopez, 91-109. Elsevier, 2011.
    Publicado • 10.1016/b978-0-443-16009-7.00016-5
  6. Rocha, Maria João; Rocha, Eduardo; Rocha, Maria João; Rocha, Eduardo. "Morphofunctional Aspects of Reproduction from Synchronous to Asynchronous fishes – An Overview". In Fish Endocrinology, editado por Reinecke, M; Zaccone, G; Kapoor, B.G.; Science Publishers, Enfield, New Hampshire, USA, 571-624. Enfield, Estados Unidos: Science Publishers Inc., 2006.
    Aceite para publicação
  7. Rocha, Eduardo; Rocha, Maria João; Monteiro, Rogério A.. "Seasonal Changes in Fish Hepatocytes and Correlations with the Endocrine System". In Fish Adaptations, editado por Kapoor, B.G.; Val, A.L., 383-403. Enfield, Estados Unidos: Science Publishers Inc., 2003.
    Publicado
  8. Rocha, Eduardo; Monteiro, Rogério A.. "Histology and Cytology of Fish Liver: A Review". In Ichthyology: Recent Research Advances, editado por Saksena, D.N., 321-344. Enfield, Estados Unidos: Science Publishers Inc., 1999.
    Publicado

Outros

Outra produção
  1. Crude extracts of marine-derived and soil fungi of the genus Neosartorya exhibit selective anticancer activity by inducing cell death in colon, breast and skin cancer cell lines. 2016. Eduardo Rocha; Ramos A.A; Bruno Castro Carvalho; Maria Prata-Sena; Tida Dethoup; Buttachon, S.; Anake Kijjoa.
    10.60692/56nsh-fx093
Atividades

Orientação

Título / Tema
Papel desempenhado		 Curso (Tipo)
Instituição / Organização
2026/01/01 - Atual HEAT.REAL.MIX – Effects of Complex Toxicant Mixtures and Heat Stress on Hepatic Detoxification and Energy Pathways: Enhancing In Vitro Models and In Vivo Relevance
Orientador de Telma Magalhães Esteves
 Ciências Biomédicas (Doutoramento)
Universidade do Porto - Instituto de Ciências Biomédicas de Abel Salazar, Portugal
2024/12/31 - Atual LIVERFigther – Effects of Combustion Organic Byproducts and Flame Retardants in a Warming World: A Proof-ofConcept Study on Fish Liver Xenobiotic Metabolism and Lipid Pathways.
Orientador de Margarida Ribeiro Vilaça
 Ciências Biomédicas (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Interdisciplinary Center for Marine and Environmental Research (CIIMAR) - U.Porto, Portugal
2024/12/31 - Atual TroutMixWarm - Structural and functional effects in fish under mixtures of lipid-lowering drugs with endocrine disruptors and warming: Exploring and refining an in vivo trout model.
Orientador de Tiago Maria Ribeiro da Cunha Quaresma Lourenço
 Ciências Biomédicas (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Interdisciplinary Center for Marine and Environmental Research (CIIMAR) - U.Porto, Portugal
2023/01/01 - Atual LivOnFire - Warming and Heat Waves influence on modulation of PAHs and pesticides impacts in fish liver using standard and complex in vitro and ex vivo cultures.
Orientador de Rodrigo Franco Alves
 Ciências Biomédicas (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Interdisciplinary Center for Marine and Environmental Research (CIIMAR) - U.Porto, Portugal
2017 - Atual Effects of mixtures of oestrogenic and progestagenic contraceptive pills ingredients on fish reproduction and gonadogenesis – An experimental study on zebrafish.
Orientador de Rodolfo Miguel Almeida Silva
 Ciências Biomédicas
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2016 - Atual Bioactive effects of seaweed- and marine fungi-derived compounds on breast cancer cell lines
Orientador de Fernanda Cristina Rodrigues Malhão Pereira
 Ciências Biomédicas (Doutoramento)
Universidade do Porto - Instituto de Ciências Biomédicas de Abel Salazar, Portugal
2024 - 2025 Seasonality of hepatocytes in cultured brown trout (Salmo trutta fario): a histofunctional study.
Orientador de Amândio Luís de Barros Rodrigues
 Ciências do Mar - Recursos Marinhos (Mestrado)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2023/09/01 - 2024/12/01 Relatório Final de Estágio: Consultoria Ambiental no âmbito da Sustentabilidade, na empresa ERM – Environmental Resources.
Coorientador
 Ciências do Mar - Recursos Marinhos (Mestrado)
ICBAS - U.Porto, Portugal
2023/09/01 - 2024/12/01 Impacts of high temperature and polycyclic aromatic hydrocarbons on detoxification - related genes and cellular integrity in the rainbow trout liver RTL-W1 cell line
Coorientador de Telma Magalhães Esteves
 Toxicologia e Contaminação Ambientais (Mestrado)
ICBAS - U.Porto, Portugal

Universidade do Porto Faculdade de Ciências, Portugal

Interdisciplinary Center for Marine and Environmental Research (CIIMAR) - U.Porto, Portugal
2022 - 2023 Determination and Risk Assessment of PAHs and PCBs in Seawater and Blue Mussels from the Coastal Area of Vila-do-Conde.
Coorientador de Ana Margarida Serra Esteves
 Mestrado em Ciências do Mar - Recursos Marinhos (Mestrado)
ICBAS - U.Porto, Portugal

Interdisciplinary Center for Marine and Environmental Research (CIIMAR) - U.Porto, Portugal
2022 - 2023 Effects of warming and some aquatic pollutants on the cytology and expression of detoxification, estrogenic and stress-related genes in trout liver cells.
Orientador
 Mestrado em Bioquímica (Mestrado)
ICBAS - U.Porto, Portugal

Interdisciplinary Center for Marine and Environmental Research (CIIMAR) - U.Porto, Portugal

Universidade do Porto Faculdade de Ciências, Portugal
2021 - 2023 Ethinylestradiol and atorvastatin effects in liver and blood lipid-related parameters of juvenile brown trout.
Orientador
 Mestrado em Ciências do Mar - Recursos Marinhos (Mestrado)
ICBAS - U.Porto, Portugal

Interdisciplinary Center for Marine and Environmental Research (CIIMAR) - U.Porto, Portugal
2020 - 2023 A protocol for anaesthesia of the oviparous fish model organism Betta Splendens.
Orientador de Bernardo Botelho Silva Pereira
Mestrado em Ciências do Mar - Recursos Marinhos (Mestrado)
ICBAS - U.Porto, Portugal

Interdisciplinary Center for Marine and Environmental Research (CIIMAR) - U.Porto, Portugal
2020 - 2023 Peixes “Ornamentais”: no biotério, no comércio e em aquários públicos.
Coorientador
 Mestrado em Ciências do Mar - Recursos Marinhos. (Mestrado)
ICBAS - U.Porto, Portugal

Interdisciplinary Center for Marine and Environmental Research (CIIMAR) - U.Porto, Portugal
2016 - 2023 Bioactive effects of seaweed compounds on breast cancer cell lines.
Orientador de Fernanda Cristina Rodrigues Malhão Pereira
 Ciências Biomédicas (Doutoramento)
Universidade do Porto - Instituto de Ciências Biomédicas de Abel Salazar, Portugal

Interdisciplinary Center for Marine and Environmental Research (CIIMAR) - U.Porto, Portugal
2021 - 2022 Effects and mechanisms of action of marine-derived preussin against the triple negative breast cancer cell line MDA-MB-231 and exploiting 2D and 3D culture
Orientador de Rosária Catarina Seabra
Oncologia (Mestrado)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Interdisciplinary Center for Marine and Environmental Research (CIIMAR) - U.Porto, Portugal
2021 - 2022 Xenoestrogenic Modulation of Sex-Steroid Related Targets in Brown Trout Primary Hepatocyte Spheroids
Coorientador
 Toxicologia e Contaminação Ambientais (Mestrado)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Interdisciplinary Center for Marine and Environmental Research (CIIMAR) - U.Porto, Portugal
2020 - 2022 Improving the histotechnical quality of skin and liver samples obtained from deceased pigs and humans for use in teaching and research on post-mortem interval.
Orientador de Paula Cristina Araújo Teixeira
 Medicina Legal (Mestrado)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019 - 2021 Quantificação de 17 compostos desreguladores endócrinos no estuário do Rio Douro - Avaliação do seu risco para a biota.
Coorientador
 Ciências do Mar – Recursos Marinhos (Mestrado)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Interdisciplinary Center for Marine and Environmental Research (CIIMAR) - U.Porto, Portugal
2019 - 2021 Caracterização e sustentabilidade do sistema socioecológico para a exploração de chicharro (Trachurus picturatus (Bowdich, 1825)) em São Miguel, Açores.
Coorientador de Gisela Sofia Correia Costa
 Ciências do Mar – Recursos Marinhos (Mestrado)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019 - 2021 Environmental Enrichment Effects on Zebrafish (Danio rerio) Fecundity, Fertility and Survival Rate.
Orientador de Maria João Abreu Santa Rosa
Ciências do Mar – Recursos Marinhos (Mestrado)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2011 - 2021 Studies of androgenic and estrogenic effects on PPARs, estrogen receptors and some related gene and phenotypic targets, using brown trout primary hepatocytes as the model system.
Orientador de Célia Cristina Carreiras Lopes
 Patologia e Genética Molecular (Doutoramento)
Universidade do Porto Faculdade de Medicina, Portugal

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2012 - 2020 Studies of androgenic and estrogenic effects on PPARs, estrogen receptors and some related gene and phenotypic targets, using brown trout primary hepatocytes as the model system
Orientador de Célia Cristina Carreiras Lopes
 Patologia e Imunologia Molecular
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Universidade do Porto Faculdade de Medicina, Portugal
2011 - 2020 Studies of androgenic and estrogenic effects on PPARs, estrogen receptors and some related gene and phenotypic targets, using brown trout primary hepatocytes as the model system.
Orientador de Célia Cristina Carreiras Lopes
 Patologia e Genética Molecular (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Interdisciplinary Center for Marine and Environmental Research (CIIMAR) - U.Porto, Portugal
2018 - 2019 Anticancer activity of seaweed compounds, alone and in combination with chemotherapy drugs, in breast cancer cell lines using 2D and 3D cell culture models
Coorientador de Ana Catarina Fernandes Pereira Rebelo de Macedo
 Toxicologia e Contaminação Ambientais (Mestrado)
2018 - 2019 Fish and sex steroids - Do juvenile fish have a distinct sex-specific steroid hormone profile? Observational study using the brown trout (Salmo trutta fario) as a model organism.
Coorientador de Joana Ferreira Borges Cordeiro Oliveira
 Ciências do Mar - Recursos Marinhos (Mestrado)
2018 - 2019 Establishment of a three-dimensional (3D) in vitro model for culture of brown trout (Salmo trutta f. fario) primary hepatocyte spheroids - Insights into 5alpha-dihydrostestosterone regulation of lipid-related genes.
Coorientador
 Contaminação e Toxicologia Ambientais (Mestrado)
Universidade do Porto - Instituto de Ciências Biomédicas de Abel Salazar, Portugal

Universidade do Porto Faculdade de Ciências, Portugal
2011 - 2019 The ecological response of reef communities to an extreme environment: implications for climate change.
Coorientador de Rita Costa San Miguel Bento Cavalcante
Biomedical Sciences (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2010 - 2019 The ecological response of reef communities to an extreme environment: implications for climate change
Coorientador de Rita Costa San Miguel Bento Cavalcante
Ciências Biomédicas (Doutoramento)
Universidade do Porto - Instituto de Ciências Biomédicas de Abel Salazar, Portugal
2017 - 2018 Characterization of brown trout fitness and gonadal maturation along the reproductive cycle
Coorientador de Diana Santiago dos Santos
Ciências do Mar - Recursos Marinhos (Mestrado)
Universidade do Porto - Instituto de Ciências Biomédicas de Abel Salazar, Portugal
2017 - 2018 Determination and risk evaluation of PAHs and PCBs in seawater samples collected at north and south of the Vila do Conde ornithological reserve
Coorientador de Ana Beatriz Teixeira Ribeiro
Ciências do Mar - Recursos Marinhos (Mestrado)
Universidade do Porto - Instituto de Ciências Biomédicas de Abel Salazar, Portugal
2013 - 2018 Microscopic Morphology of the Liver of the Guppy (Poecilia reticulata)
Orientador de Sisandra Lurdes de Campos Pacheco e Ruela de Sousa
 Ciências Biomédicas (Doutoramento)
Universidade do Porto - Instituto de Ciências Biomédicas de Abel Salazar, Portugal
2013 - 2018 Microscopic Morphology of the Liver of the Guppy (Poecilia reticulata).
Orientador de Sisandra Lurdes de Campos Pacheco e Ruela de Sousa
 Ciências do Mar e do Ambiente (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2016 - 2017 Screening of larvicidal activity of seaweed extracts against the mosquito Aedes aegypti
Coorientador de Mafalda Santos Coutinho
Toxicologia e Contaminação Ambientais (Mestrado)
Universidade do Porto - Instituto de Ciências Biomédicas de Abel Salazar, Portugal

Universidade do Porto - Faculdade de Ciências, Portugal
2015 - 2016 Avaliação multiparamétrica da aclimatação de juvenis de truta fário (Salmo trutta f. fario) para estudos experimentais
Coorientador de Joana Luísa Ferreira Gomes Alves Costa
 Ciências do Mar - Recursos Marinhos (Mestrado)
Universidade do Porto - Instituto de Ciências Biomédicas de Abel Salazar, Portugal
2015 - 2016 A combinação simultânea de peixes larvívoros com pesticidas como uma estratégia de controlo de vetores da malária — Um estudo experimental com Poecilia reticulata e três pesticidas
Orientador de Ana Rita Monteiro Ysenbout Mogas
 Ciências do Mar - Recursos Marinhos (Mestrado)
Universidade do Porto - Instituto de Ciências Biomédicas de Abel Salazar, Portugal
2015 - 2016 Gonad Differentiation in Guppy Fish and Testing Strategies for the Production of Sterile and All-Female Offspring
Orientador de Diana Bastos Serrano de Almeida
 Ciências do Mar – Recursos Marinhos (Mestrado)
Universidade do Porto - Instituto de Ciências Biomédicas de Abel Salazar, Portugal
2015 - 2016 Induction of Gonadal Growth/Maturation in the Ornamental Fishes Epalzeorhynchos bicolor and Carassius auratus and Stereological Validation in C. auratus of Histological Grading Systems for Assessing the Ovary and Testis Statuses
Orientador de Lia Gomes da Silva Henriques
 Ciências do Mar – Recursos Marinhos (Mestrado)
Universidade do Porto - Instituto de Ciências Biomédicas de Abel Salazar, Portugal
2015 - 2016 Combined effects of increased temperature and exposure to the progestin levonorgestrel on zebrafish (Danio rerio) fitness and breeding
Coorientador de Daniela Sofia Barbosa Rodrigues
 Toxicologia e Contaminação Ambientais (Mestrado)
Universidade do Porto - Instituto de Ciências Biomédicas de Abel Salazar, Portugal

Universidade do Porto - Faculdade de Ciências, Portugal
2015 - 2016 Anticancer activity against glioblastoma cell lines by compounds present in algae, alone and in combination with anticancer drugs
Coorientador de Tânia Patrícia Teixeira Almeida
 Toxicologia e Contaminação Ambientais (Mestrado)
Universidade do Porto - Instituto de Ciências Biomédicas de Abel Salazar, Portugal

Universidade do Porto - Faculdade de Ciências, Portugal
2015 - 2016 Anticancer activity against glioblastoma cell lines by compounds present in algae, alone and in combination with anticancer drugs
Coorientador de Joana Rodrigues Neves Ferreira
 Toxicologia e Contaminação Ambientais (Mestrado)
Universidade do Porto - Instituto de Ciências Biomédicas de Abel Salazar, Portugal

Universidade do Porto - Faculdade de Ciências, Portugal
2012 - 2016 Environmental monitoring and molecular mechanistic insights on pesticides in water and in the bivalve Scrobicularia plana, from Mondego and Tagus estuaries and Ria Formosa Lagoon
Orientador de Catarina da Rocha Cruzeiro
 Ciências Biomédicas (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2008 - 2016 Ovary apoptosis in zebrafish (Danio rerio): estrogenic regulation and role in sexual differentiation
Coorientador de Ana Catarina Gonçalves Luzio
 Ciências do Ambiente (Doutoramento)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2010 - 2015 Canine mammary tumors: quantitative morphological and genetic studies
Coorientador de Marta Susana Amaro dos Santos
 Ciências Veterinárias (Doutoramento)
Universidade do Porto - Instituto de Ciências Biomédicas de Abel Salazar, Portugal
2010 - 2015 A qualitative and quantitative study of the microscopic morphology of the nervous ganglia of the bivalve peppery furrow shell (Scrobicularia plana).
Orientador de Sukanlaya Tantiwisawaruji
 Ciências Biomédicas (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2013 - 2014 In vitro screening of the anticancer activity of marine and soil-derived fungi extracts and compounds used alone and combined with doxorubicin: Evaluation of the anticancer properties of fungi extracts and compounds alone and in combination with doxorubicin in lung cancer cells.
Coorientador de Bruno Miguel Castro Carvalho. Mestrado
 Ciências do Mar – Recursos Marinhos (Mestrado)
Universidade do Porto - Instituto de Ciências Biomédicas de Abel Salazar, Portugal
2013 - 2014 Anticancer activity of marine-derived fungi extracts and isolated compound in human cancer cell lines
Coorientador de Maria Prata e Castro de Sena Esteves
 Ciências do Mar - Recursos Marinhos (Mestrado)
Universidade do Porto - Instituto de Ciências Biomédicas de Abel Salazar, Portugal
2013 - 2014 Identificação e desenvolvimento larvar de peixes tropicais do Indo Pacífico no Oceanário de Lisboa
Orientador de Lurdes Raquel Santos Ferreira
 Ciências do Mar - Recursos Marinhos (Mestrado)
Universidade do Porto - Instituto de Ciências Biomédicas de Abel Salazar, Portugal
2013 - 2014 Estrogenic exposure impacts in the frequency and stereological parameters of both induced preneoplastic liver lesions and normal hepatocytes of the brown trout.
Orientador de Sara Diana Moreira Pereira
 Oncologia (Mestrado)
Universidade do Porto - Instituto de Ciências Biomédicas de Abel Salazar, Portugal
2008 - 2013 A toxicopathology survey of the River Bregalnica using the barbell (Barbus peloponnesius, Valenciennes, 1844) as bioindicator
Coorientador de Katerina Rebok
 Biology (Doutoramento)
Saints Cyril and Methodius University - Faculty of Natural Sciences and Mathematics, Macedónia
2007 - 2013 Age and gender influences on the rat liver model: quantitative morphological studies of Age and gender influences on the rat liver model: quantitative morphological studies of hepatic stellate cells, hepatocytes and Kupffer cells and of selected related functional parameters hepatocytes and Kupffer cells and of selected related functional parameters
Orientador de Ricardo Jorge Córdova Marcos
 Ciências Veterinárias (Doutoramento)
Universidade do Porto - Instituto de Ciências Biomédicas de Abel Salazar, Portugal
2011 - 2012 Optimisation and validation of a GC-MS/MS method for the determination of polycyclic aromatic hydrocarbons in mussel samples by QuEChERS-based extraction.
Coorientador de Susana Paula Pinto Velhote
 Toxicologia e Contaminação Ambientais (Mestrado)
Universidade do Porto - Instituto de Ciências Biomédicas de Abel Salazar, Portugal

Universidade do Porto - Faculdade de Ciências, Portugal
2011 - 2012 Hepatocyte primary cell culture in brown trout (Salmo trutta): studies of estrogenic endocrine disruption and peroxisome dynamics in the liver.
Coorientador de Nádia da Silva Ferreira
 Toxicologia e Contaminação Ambientais (Mestrado)
Universidade do Porto - Instituto de Ciências Biomédicas de Abel Salazar, Portugal

Universidade do Porto - Faculdade de Ciências, Portugal
2010 - 2011 Do Estrogens ande Androgens Modulate Fish Liver Peroxisomes? Experimental Studies on the Influences of Temperature, Sex, and Ethynylestradiol, using the Platyfish (Xiphophorus maculatus) as the Model Organism.
Orientador de Francisco Figueiredo
 Ciências do Mar - Recursos Marinhos (Mestrado)
Universidade do Porto - Instituto de Ciências Biomédicas de Abel Salazar, Portugal
2010 - 2011 Can fish liver melanomacrophages be modulated by xenoestrogenic and xenoandrogenic pollutants? Experimental studies on the influences of temperature, sex, and ethynylestradiol, using the platyfish as the model organism.
Orientador de Carlos Miguel Ferreira
 Contaminação e Toxicologia Ambientais (Mestrado)
Universidade do Porto - Instituto de Ciências Biomédicas de Abel Salazar, Portugal

Universidade do Porto - Faculdade de Ciências, Portugal
2010 - 2011 In vitro studies on the regulation and toxicant disruption of hepatic peroxisomes by estrogenic and peroxisome proliferator compounds.
Orientador de Ivone Pinheiro
 Toxicologia e Contaminação Ambientais (Mestrado)
Universidade do Porto - Instituto de Ciências Biomédicas de Abel Salazar, Portugal

Universidade do Porto - Faculdade de Ciências, Portugal
2007 - 2011 Analysis of pharmaceuticals in the Douro river estuary and test of biological effects using zebrafish as a model.
Coorientador de Tânia Vieira Madureira
 Ciências Biomédicas (Doutoramento)
Universidade do Porto - Instituto de Ciências Biomédicas de Abel Salazar, Portugal
2005 - 2011 Light Microscopic Studies of Toxicopathic Changes in Fishes from the Tinhela and Vizela Rivers, and from the Mondego, Douro and Ave Estuaries
Coorientador de João Soares Carrola
 Ciências do Ambiente (Doutoramento)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2009 - 2010 Characterization of the trout liver cell line RTL-W1 and its potential for carcinogenesis-related studies.
Orientador de Fernanda Cristina Rodrigues Malhão Pereira
 Oncologia
Universidade do Porto - Instituto de Ciências Biomédicas de Abel Salazar, Portugal
2009 - 2010 An histopathological and stereological study of proliferative hepatocellular lesions in a fish model of experimental carcinogenesis and in a sentinel fish.
Orientador de Marta Susana Amaro dos Santos
 Oncologia (Mestrado)
Universidade do Porto - Instituto de Ciências Biomédicas de Abel Salazar, Portugal
2004 - 2010 Chemical identification and monitoring of natural and xenoestrogens compounds in the estuaries of the estuaries of the Portuguese rivers Douro, Mondego and Sado – Insights on their Disruption Potential by In Vitro Exposures of Testis From the Model Organism Nile Tilapia (Oreochromis niloticus)
Orientador de Cláudia Maria Rosa Ribeiro
 Ciências Biomédicas (Doutoramento)
Universidade do Porto - Instituto de Ciências Biomédicas de Abel Salazar, Portugal
2003 - 2009 Differentiation, development and growth of the blackspot seabream (Pagellus bogaraveo) muscle
Orientador de Paula Cristina Paulo Videira da Silva
 Ciências Biomédicas (Doutoramento)
Universidade do Porto - Instituto de Ciências Biomédicas de Abel Salazar, Portugal
2001 - 2008 The peroxisomes of brown trout (Salmo trutta fario): regulation by estrogens
Coorientador de Carla Maria de Carvalho Batista Pinto
 Ciências Biomédicas (Doutoramento)
Universidade do Porto - Instituto de Ciências Biomédicas de Abel Salazar, Portugal
2001 - 2008 Seasonal and toxicological study of brown trout (Salmo trutta) kidney and liver peroxisomes.
Coorientador de Albina Dolores Castro Resende
 Ciências Biomédicas (Doutoramento)
Universidade do Porto - Instituto de Ciências Biomédicas de Abel Salazar, Portugal
2002 - 2004 The liver in female Salmo letnica Kar. (Teleostei, Salmonidae) during the reproductive cycle: A microscopic study of the natural population of Lake Ohrid.
Coorientador de Maja Jordanova
 Biology (Doutoramento)
Saints Cyril and Methodius University - Faculty of Natural Sciences and Mathematics, Macedónia
2002 - 2003 Efeito do carbaril em parâmetros bioquímicos do estresse oxidativo e na histologia de fígado de tilápia (Oreochromis niloticus).
Coorientador de Pedro Alexandre Cardoso Matos
 Produção Animal (Mestrado)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2001 - 2003 Histopatologia hepática como biomarcador da poluição em sistemas aquáticos. Bacias hidrográficas dos rios Douro e Ave
Coorientador de João Soares Carrola
 Produção Animal
Universidade de Trás-os-Montes e Alto Douro, Portugal
2000 - 2001 Efeitos do 17beta-estradiol e de alquilfenóis (pseudo-estrogénios) nos peroxissomas hepáticos de truta fário
Coorientador de Alexandra Neto
 Ciências do Mar - Recursos Marinhos (Mestrado)
Universidade do Porto - Instituto de Ciências Biomédicas de Abel Salazar, Portugal
1998 - 1999 Caracterização morfo-funcional de células inter-hepatocíticas de truta fário (Salmo trutta).
Coorientador de Albina Dolores Castro Resende
 Ciências do Mar - Recursos Marinhos (Mestrado)
Universidade do Porto - Instituto de Ciências Biomédicas de Abel Salazar, Portugal

Arbitragem científica em revista

Nome da revista (ISSN) Editora
2024 - Atual Discover Toxicology ( 3004-8893) Springer Nature
2022 - Atual Animals (2076-2615) MDPI
2021 - Atual Hydrobiology (2673-9917) MDPI
2021 - Atual Journal of Applied Pharmaceutical Science (2231-3354) Open Science Publishers LLP
2020 - Atual Toxics (2305-6304) MDPI
2018 - Atual Toxicological & Environmental Chemistry (0277-2248) Taylor & Francis
2016 - Atual Asian Pacific Journal of Tropical Medicine (1995-7645) Wolters Kluwer - Medknow Publications
2016 - Atual Indian Journal of Anatomy (2455-622X) Red Flower Publication Pvt. Ltd.
Distinções

Prémio

1990 Best Student Award
Fundação Engenheiro António de Almeida, Portugal