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Maria dos Anjos Lopez Macedo / Anjos L. Macedo (ALM) PhD in Chemistry in 1994/12/09 by Universidade Nova de Lisboa. Assistant Professor at NOVA-FCT ( Faculty of Sciences and Technology) and Independent Researcher at UCIBIO, NOVA-FCT (ucibio.pt/people/anjos-macedo). --> ALM has been lecturing NMR in Structural Biology and Bioinorganic Chemistry, 1st and 2nd cycles of Biochemistry, and coordinating the Doctoral Program in Biochemistry @Chemistry Dep. --> 2019, ALM was dedicated to transferring technology to the market, launching a startup as a co-founder, and participating in a 16 weeks accelerator program in sustainable aquaculture for innovative startups, HATCH (www.hatch.blue/accelerator) for the development of a biosensor for the detection of nitrogen compounds in aquaculture. --> ALM has been involved in several projects as an independent researcher @UCIBIO | Understanding biomolecular function in disease (ucibio.pt/people/anjos-macedo): - NMR applications in Paramagnetic Systems / Metalloproteins: joint PhD project | José Pedro Silva (Collaboration C. Luchinat, CERM, UFlorence & C.Geraldes, UCoimbra) - Monitoring EVs and Gla-rich proteins in vascular calcification events (Collaboration D. Simes, CCMAR - UAlgarve & AP Matos, CiiEM-Caparica) - Mode of action of Antimicrobial Peptides | FCT funded project (Collaboration: J. Caldeira, UCIBIO & CiiEM; H.Albergaria, LNEG | project PI) - NMR studies of Heme binding proteins and heme scavenging solutions (Collaboration: B. Goodfellow, UAveiro; M. Picciolli, CERM, UFlorence) - The Biogenesis of Iron-sulfur Proteins: from Cellular Biology to Molecular Aspects (FeSBioNet) COST Action CA 15133 (http://www.cost.eu/COST_Actions/ca/CA15133) Management Committee | Coordination: Mario Piccioli, CERM --> Member of the Management Board - Portuguese Nuclear Magnetic Resonance Network (http://ptnmr.dq.ua.pt) PTNMR Mission: provide the scientific community with access to modern and up-to-date NMR spectrometers housed in scientific institutions with competence and scientific expertise on the use of this type of equipment. --> Research contributions (50 publications, including 3 reviews/book chapters): NMR applied to the determination of protein structure & interactions. Topics: protein-heme interactions; the role of human Gla-rich Proteins in vascular calcification and inflammatory events; understanding the effect of sodium thiocyanate on human Carbonic Anhydrase 2; TEM applications to EVs detection in vascular calcification events. h-index = 20; 1275 citations (456 in the last 5 years)
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Identificação

Identificação pessoal

Nome completo
Maria dos Anjos Lopez Macedo
Data de nascimento
1963/10/02
Género
Feminino

Nomes de citação

  • Anjos L. Macedo
  • Anjos Macedo

Identificadores de autor

Ciência ID
8D15-B778-09B7
ORCID iD
0000-0002-2613-4838

Endereços de correio eletrónico

  • anjos.macedo@fct.unl.pt (Profissional)

Telefones

Fax
  • 212948550 Ext.: 0939 (Profissional)

Moradas

  • UCIBIO @ Chemistry Department, Faculty of Sciences and Technology - Univ. NOVA de Lisboa (FCT-NOVA) Campus de Caparica, 2829-516, Caparica, Almada, Portugal (Profissional)

Websites

Domínios de atuação

  • Ciências Naturais - Ciências Biológicas - Bioquímica

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Espanhol; Castelhano Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Francês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador independente (B1) Utilizador proficiente (C1)
Inglês Utilizador independente (B1) Utilizador proficiente (C1) Utilizador independente (B1) Utilizador independente (B1)
Português Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Formação
Grau Classificação
2019/02/28 - 2019/07/02
Concluído
 HiTech training program 2019 (Outros)
Especialização em Technology commercialization and entrepreneurship - 4 Months training program
Universidade Nova de Lisboa Nova School of Business and Economics, Portugal
 na
1994/12/09
Concluído
 Química (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
"Structural Studies on Ferredoxins. Multidimensional NMR Techniques applied to Paramagnetic Systems" (TESE/DISSERTAÇÃO)
 Louvor e Distinção
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2015 - Atual Investigador principal (carreira) (Investigação) Universidade Nova de Lisboa - Faculdade de Ciências e Tecnologia, Portugal
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2007 - 2013 Investigador Auxiliar (carreira) (Investigação) Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento 		Empregador
1994/12/09 - Atual Professor Auxiliar (Docente Universitário) Universidade Nova de Lisboa - Faculdade de Ciências e Tecnologia, Portugal
1986/10/01 - 1994/12/08 Assistente (Docente Universitário) Universidade Nova de Lisboa - Faculdade de Ciências e Tecnologia, Portugal

Cargos e Funções

Categoria Profissional
Instituição de acolhimento 		Empregador
2019/09/05 - 2020/04 Co-Founder Nitrogen Sensing Solutions, Lda, Portugal

Outros

Categoria Profissional
Instituição de acolhimento 		Empregador
2009/03/09 - 2012/12/31 Executive Coordinator, Scientific Council for Health and Life Sciences Fundação para a Ciência e a Tecnologia, Portugal
1985/10/01 - 1986/09/30 Demonstrator Universidade Nova de Lisboa - Faculdade de Ciências e Tecnologia, Portugal
Projetos

Bolsa

Designação Financiadores
2018/10/01 - Atual BIOCONTROL - Improving biological control of industrial bioethanol production processes by using Saccharomyces cerevisiae's own weapons
PTDC/BII-BIO/31761/2017
Investigador
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2013/07 - 2016/06 NMR Net - National Facility for Nuclear Magnetic Resonance: from Molecular Structure and Dynamics to Protein Function, Cell Physiology, and Metabolomics
127013
Provided by PTCRIS: 127013
 Fundação para a Ciência e a Tecnologia, I.P.
2012/02 - 2015/01 Mammalian and Bacterial Aldehyde Oxidases: Structure, mechanism and insights into cofactor binding and protein maturation
Provided by PTCRIS: 118377
118377
 Fundação para a Ciência e a Tecnologia, I.P.
2012/02 - 2015/01 Nitric Oxide Synthase targeting with Re(I)/99mTc(I)-complexes containing L-Arg derivatives: A structure-activity study
121752
Provided by PTCRIS: 121752
 Fundação para a Ciência e a Tecnologia, I.P.
2011/03 - 2014/08 Ligand-binding stereospecificity of grapevine dirigent proteins: chiral induction for a new generation of fungicides
112340
Provided by PTCRIS: 112340
 Fundação para a Ciência e a Tecnologia, I.P.
2009/01 - 2012/06 Sol-gel entrapped cutinase: Understanding enzyme/matrix interactions via fluorescence, NMR and DRIFT spectroscopies, and site-directed mutagenesis
64744
Provided by PTCRIS: 64744
 Fundação para a Ciência e a Tecnologia, I.P.
2008/01 - 2011/09 A combined approach of X-ray Crystallography, NMR and Computational Chemistry for the study of the molecular interactions that define the ligand specificity in cellulosomal Carbohydrate Binding Modules
68286
Provided by PTCRIS: 68286
 Fundação para a Ciência e a Tecnologia, I.P.
2008/01 - 2011/07 Structural and functional studies of the SOUL/HBP family of heme binding proteins
64203
Provided by PTCRIS: 64203
 Fundação para a Ciência e a Tecnologia, I.P.
2007/01 - 2009/12 Biocorrosion in dental materials
Provided by PTCRIS: 83421
83421
 Fundação para a Ciência e a Tecnologia, I.P.
2007/01 - 2009/04 Molecular determinants of ligand specificity in carbohydrate-binding modules and cohesin-dockerin complexes
Provided by PTCRIS: 82210
82210
 Fundação para a Ciência e a Tecnologia, I.P.
2005/07 - 2008/04 Biocorrosion in dental materials
56029
Provided by PTCRIS: 56029
 Fundação para a Ciência e a Tecnologia, I.P.
2005/07 - 2007/12 Molecular determinants of ligand specificity in carbohydrate-binding modules and cohesin-dockerin complexes
59118
Provided by PTCRIS: 59118
 Fundação para a Ciência e a Tecnologia, I.P.
2002/01 - 2005/09 High-Pressure NMR spectroscopy of polymers and biopolymers in CO2 emulsions.
Provided by PTCRIS: 42313
42313
 Fundação para a Ciência e a Tecnologia, I.P.
2000/01 - 2002/12 A Structural Study of the Presequence of 5-Aminolevulinate Synthase (ALAS), the First Enzyme of the Heme Biosynthetic Pathway
Provided by PTCRIS: 991
991
 Fundação para a Ciência e a Tecnologia, I.P.

Projeto

Designação Financiadores
2021/01/01 - 2025/12/31 Institute for Health and Bioeconomy
LA/P/0140/2020
10.54499/LA/P/0140/2020
Co-Investigador Responsável (Co-IR)
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal

Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal

Universidade NOVA de Lisboa, Portugal

INESC Microsistemas e Nanotecnologias, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Associação para a Inovação e Desenvolvimento da FCT, Portugal

Unidade de Ciências Biomoleculares Aplicadas, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2020/01/01 - 2023/12/31 Applied Molecular Biosciences Unit
UIDB/04378/2020
10.54499/UIDB/04378/2020
Co-Investigador Responsável (Co-IR)
Universidade NOVA de Lisboa, Portugal

Unidade de Ciências Biomoleculares Aplicadas, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Associação para a Inovação e Desenvolvimento da FCT, Portugal

Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal

Universidade do Porto, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2016/04/01 - 2019/09/30 Nanoagentes de monoxido de carbono COGSs para combater a Artrite Reumatoide
PTDC/QEQ-MED/1902/2014
Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal

Unidade de Ciências Biomoleculares Aplicadas, Portugal

Universidade Nova de Lisboa Associação para a Inovação e Desenvolvimento da FCT, Portugal

Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
Fundação para a Ciência e a Tecnologia
Concluído

Outro

Designação Financiadores
2016/04/15 - 2020/10/14 COST Action CA 15133 - The Biogenesis of Iron-sulfur Proteins: from Cellular Biology to Molecular Aspects (FeSBioNet)
COST Action CA 15133
MC member
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal

Università degli Studi di Firenze Centro di Ricerca di Risonanze Magnetiche, Itália
European Union
Concluído
Produções

Publicações

Artigo em conferência
  1. Anjos L. Macedo. "Saccharomycin, a biocide from S. cerevisiae that kill-off other yeasts". 2019.
    10.1080/07853890.2018.1561858
Artigo em revista
  1. Carla Viegas; Joana Carreira; Teresa M. Maia; Anjos L. Macedo; António P. Matos; José Neves; Dina Simes. "Gla Rich Protein (GRP) Mediates Vascular Smooth Muscle Cell (VSMC) Osteogenic Differentiation, Extracellular Vesicle (EV) Calcification Propensity, and Immunomodulatory Properties". International Journal of Molecular Sciences (2024): https://doi.org/10.3390/ijms252212406.
    10.3390/ijms252212406
  2. Lucia Gigli; José Malanho Silva; Linda Cerofolini; Anjos L. Macedo; Carlos F. G. C. Geraldes; Elizaveta A. Suturina; Vito Calderone; et al. "Machine Learning-Enhanced Quantum Chemistry-Assisted Refinement of the Active Site Structure of Metalloproteins". Inorganic Chemistry (2024): https://doi.org/10.1021/acs.inorgchem.4c01274.
    10.1021/acs.inorgchem.4c01274
  3. Silva, José Malanho; Cerofolini, Linda; Carvalho, Ana Luísa; Ravera, Enrico; Fragai, Marco; Parigi, Giacomo; Anjos L. Macedo; Geraldes, Carlos F.G.C.; Luchinat, Claudio. "Elucidating the concentration-dependent effects of thiocyanate binding to carbonic anhydrase". Journal of Inorganic Biochemistry 244 (2023): 112222. http://dx.doi.org/10.1016/j.jinorgbio.2023.112222.
    Publicado • 10.1016/j.jinorgbio.2023.112222
  4. Carla S. B. Viegas; Nuna Araújo; Joana Carreira; Jorge Filipe Pontes; Anjos L. Macedo; Maurícia Vinhas; Ana S. Moreira; et al. "Nanoencapsulation of Gla-Rich Protein (GRP) as a Novel Approach to Target Inflammation". International Journal of Molecular Sciences (2022): https://www.mdpi.com/1422-0067/23/9/4813.
    10.3390/ijms23094813
  5. Goodfellow, Brian J.; Freire, Filipe; Carvalho, Ana Luísa; Aveiro, Susana S.; Charbonnier, Peggy; Moulis, Jean-Marc; Delgado, Leonildo; et al. Autor correspondente: Macedo, Anjos L.. "The SOUL family of heme-binding proteins: Structure and function 15 years later". Coordination Chemistry Reviews 448 (2021): 214189. http://dx.doi.org/10.1016/j.ccr.2021.214189.
    10.1016/j.ccr.2021.214189
  6. Anjos L. Macedo; Claudio Luchinat; Jose Malanho Silva; Linda Cerofolini; Vito Calderone; Carlos F.G.C. Geraldes; Giacomo Parigi; et al. "Metal centers in biomolecular solid-state NMR". Journal of Structural Biology 206 1 (2019): 99-109. http://dx.doi.org/10.1016/j.jsb.2018.11.013.
    Publicado • 10.1016/j.jsb.2018.11.013
  7. Cerofolini, L.; Silva, J.M.; Ravera, E.; Romanelli, M.; Geraldes, C.F.G.C.; Macedo, A.L.; Fragai, M.; Parigi, G.; Luchinat, C.. "How Do Nuclei Couple to the Magnetic Moment of a Paramagnetic Center? A New Theory at the Gauntlet of the Experiments". Journal of Physical Chemistry Letters 10 13 (2019): 3610-3614. http://www.scopus.com/inward/record.url?eid=2-s2.0-85068179277&partnerID=MN8TOARS.
    10.1021/acs.jpclett.9b01128
  8. Silva, Jose Malanho; Giuntini, Stefano; Cerofolini, Linda; Geraldes, Carlos F. G. C.; Macedo, Anjos L.; Ravera, Enrico; Fragai, Marco; Luchinat, Claudio; Calderone, Vito. "Non-crystallographic symmetry in proteins: Jahn-Teller-like and Butterfly-like effects?". Journal of Biological Inorganic Chemistry 24 1 (2019): 91-101. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000459431600009&KeyUID=WOS:000459431600009.
    10.1007/s00775-018-1630-0
  9. Viegas, C.S.B.; Santos, L.; Macedo, A.L.; Matos, A.A.; Silva, A.P.; Neves, P.L.; Staes, A.; et al. "Chronic kidney disease circulating calciprotein particles and extracellular vesicles promote vascular calcification: A role for GRP (Gla-Rich Protein)". Arteriosclerosis, Thrombosis, and Vascular Biology 38 3 (2018): 575-587. http://www.scopus.com/inward/record.url?eid=2-s2.0-85046012631&partnerID=MN8TOARS.
    10.1161/ATVBAHA.117.310578
  10. Viegas, Carla S. B.; Macedo, Anjos L.; Matos, Antonio A.; Silva, Ana P.; Neves, Pedro L.; Vermeer, Cees; Schurgers, Leon; Simes, Dina C.. "Gla-rich protein, a vitamin K-dependent protein involved in inflammation and calcification-related diseases". Annals of Medicine 50 (2018): S1-S2. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000430497900004&KeyUID=WOS:000430497900004.
  11. Morais, Rute; Viegas, Carla S. B.; Simes, Dina C.; Matos, António P. A.; Macedo, Anjos L.. "Application of TEM techniques for the study of vascular calcification: Monitoring extracellular vesicles and nanogold immunodetection of fetuin-A, GRP, and CD9". Ultrastructural Pathology 41 1 (2017): 130-132. http://dx.doi.org/10.1080/01913123.2016.1272670.
    Publicado • 10.1080/01913123.2016.1272670
  12. Viegas CS; Macedo AL; Morais R; Santos L; Matos AP; Silva AP; Neves P; Simes DC. "Dysregulated fetuin-mineral complexes are linked to vascular calcification in chronic kidney disease: The role of Gla-rich protein.". (2017): http://europepmc.org/abstract/med/28230466.
    10.1080/01913123.2016.1269490
  13. Viegas, C.S.B.; Costa, R.M.; Santos, L.; Videira, P.A.; Silva, Z.; Araújo, N.; Macedo, A.L.; et al. "Gla-rich protein function as an anti-inflammatory agent in monocytes/macrophages: Implications for calcification-related chronic inflammatory diseases". PLoS ONE 12 5 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85019353843&partnerID=MN8TOARS.
    10.1371/journal.pone.0177829
  14. Macedo, A.L.; Viegas, C.S.B.; Matos, A.P.A.; Simes, D.C.. "Extracellular vesicles and circulating fetuin-mineral complexes in vascular calcification; Studies by em techniques". Microscopy and Microanalysis 22 (2016): 16-17. http://www.scopus.com/inward/record.url?eid=2-s2.0-85014510834&partnerID=MN8TOARS.
    Publicado • 10.1017/S1431927616000271
  15. Zamora-Carreras, Hector; Torres, Maria; Bustamante, Noemi; Macedo, Anjos L.; Rodriguez, Rosalia; Villalba, Mayte; Bruix, Marta. "The C-terminal domains of two homologous Oleaceae beta-1,3-glucanases recognise carbohydrates differently: Laminarin binding by NMR". Archives of Biochemistry and Biophysics 580 (2015): 93-101. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000358823700011&KeyUID=WOS:000358823700011.
    10.1016/j.abb.2015.07.004
  16. Viegas, Carla S. B.; Rafael, Marta S.; Enriquez, Jose L.; Teixeira, Alexandra; Vitorino, Rui; Luis, Ines M.; Costa, Ruben M.; et al. "Gla-Rich Protein Acts as a Calcification Inhibitor in the Human Cardiovascular System". Arteriosclerosis Thrombosis and Vascular Biology 35 2 (2015): 399-408. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000348215100022&KeyUID=WOS:000348215100022.
    10.1161/ATVBAHA.114.304823
  17. Viegas, A.; Sardinha, J.; Freire, F.; Duarte, D.F.; Carvalho, A.L.; Fontes, C.M.G.A.; Romão, M.J.; Macedo, A.L.; Cabrita, E.J.. "Solution structure, dynamics and binding studies of a family 11 carbohydrate-binding module from clostridium thermocellum (Ct CBM11)". Biochemical Journal 451 2 (2013): 289-300. http://www.scopus.com/inward/record.url?eid=2-s2.0-84875612824&partnerID=MN8TOARS.
    10.1042/BJ20120627
  18. Goodfellow, Brian J.; Anjos L. Macedo; Moura, I.; Moura, José J. G. ; Nunes, Sofia G.; Volkman, B.F.; Duarte, Iven C.F.. Autor correspondente: Goodfellow, Brian J.. "An NMR structural study of nickel-substituted rubredoxin". Journal of Biological Inorganic Chemistry 15 3 (2010): 409-420.
    10.1007/s00775-009-0613-6
  19. Micaelo, Nuno M.. "Tetrapyrrole binding affinity of the murine and human p22HBP heme-binding proteins". Journal of Molecular Graphics & Modelling 29 3 (2010): 396-405.
    10.1016/j.jmgm.2010.07.008
  20. Freire, Filipe. "Preliminary structural characterization of human SOUL, a haem-binding protein". Acta Crystallographica Section F-Structural Biology and Crystallization Communications 65 (2009): 723-726.
    10.1107/S174430910902291X
  21. Viegas, Aldino. "Solution structure of hirsutellin A - new insights into the active site and interacting interfaces of ribotoxins". Febs Journal 276 8 (2009): 2381-2390.
    10.1111/j.1742-4658.2009.06970.x
  22. Viegas A; Macedo AL; Cabrita EJ. "Ligand-based nuclear magnetic resonance screening techniques.". (2009): http://europepmc.org/abstract/med/20694687.
    10.1007/978-1-60761-244-5_6
  23. Viegas, Aldino. "Molecular determinants of ligand specificity in family 11 carbohydrate binding modules - an NMR, X-ray crystallography and computational chemistry approach". Febs Journal 275 10 (2008): 2524-2535.
    10.1111/j.1742-4658.2008.06401.x
  24. Temtem, Marcio. "Molecular interactions and CO(2)-philicity in supercritical CO(2). A high-pressure NMR and molecular modeling study of a perfluorinated polymer in scCO(2)". Journal of Physical Chemistry B 111 6 (2007): 1318-1326.
    10.1021/jp0660233
  25. Dias, J.S.; Macedo, A.L.; Ferreira, G.C.; Peterson, F.C.; Volkman, B.F.; Goodfellow, B.J.. "Erratum:The first structure from the SOUL/HBP family of heme-binding proteins, murine P22HBP (Journal of Biological Chemistry (2006) 281, (31553-31561))". Journal of Biological Chemistry 281 50 (2006): http://www.scopus.com/inward/record.url?eid=2-s2.0-33846002771&partnerID=MN8TOARS.
  26. Avecilla, Fernando. "Crystal structure of the V-V dimer [V2O2(mu-O)(dmpp)(2)(OCH3)(2)] and its equilibrium with the V-V trimer [V3O3(mu-O)3(dmpp)(3)(H2O](H2O)(2) in methanol/water solutions". European Journal of Inorganic Chemistry 18 (2006): 3586-3594.
    10.1002/ejic.200600301
  27. Rodrigues, PM. "Desulfovibrio gigas ferredoxin II: redox structural modulation of the [3Fe-4S] cluster". Journal of Biological Inorganic Chemistry 11 3 (2006): 307-315.
    10.1007/s00775-005-0077-2
  28. Dias, Jorge S.. "The first structure from the SOUL/HBP family of heme-binding proteins, murine P22HBP". Journal of Biological Chemistry 281 42 (2006): 31553-31561.
    10.1074/jbc.M605988200
  29. Dias, JS. "H-1, N-15 and C-13 resonance assignments of the heme-binding protein murine p22HBP". Journal of Biomolecular Nmr 32 4 (2005): 338-338.
    10.1007/s10858-005-0470-8
  30. Rodrigues, PM. "Spectroscopic characterization of a novel 2 x [4Fe-4S] ferredoxin isolated from Desulfovibrio desulfuricans ATCC 27774". Inorganica Chimica Acta 356 (2003): 215-221.
    10.1016/S0020-1693(03)00472-9
  31. Rodrigues, PM. "Characterization of a new 8Fe protein isolated from Desulfovibrio desulfuricans ATCC 27774". Journal of Inorganic Biochemistry 96 1 (2003): 220-220.
    10.1016/S0162-0134(03)80753-5
  32. Rodríguez-Infante, C.; Esteban, D.; Avecilla, F.; De Blas, A.; Rodríguez-Blas, T.; Mahía, J.; Macedo, A.L.; Geraldes, C.F.G.C.. "Copper complexes with bibracchial lariat ethers: From mono- to binuclear structures". Inorganica Chimica Acta 317 1-2 (2001): 190-198. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035962758&partnerID=MN8TOARS.
    10.1016/S0020-1693(01)00425-X
  33. Rodrigues, P. "Characterization of recombinant Desulfovibrio gigas ferredoxin". Biochemical and Biophysical Research Communications 289 2 (2001): 630-633.
    10.1006/bbrc.2001.6016
  34. Goodfellow, BJ. "The solution structure and heme binding of the presequence of murine 5-aminolevulinate synthase". Febs Letters 505 2 (2001): 325-331.
    10.1016/S0014-5793(01)02818-6
  35. Sanakis, Y. "Evidence for antisymmetric exchange in cuboidal [3Fe-4S](+) clusters". Journal of the American Chemical Society 122 48 (2000): 11855-11863.
    10.1021/ja002658i
  36. Battistuzzi, G. "Redox thermodynamics of low-potential iron-sulfur proteins". Journal of Biological Inorganic Chemistry 5 6 (2000): 748-760.
    10.1007/s007750000164
  37. Battistuzzi, G.; D'Onofrio, M.; Borsari, M.; Sola, M.; Macedo, A.L.; Moura, J.J.G.; Rodrigues, P.. "Redox thermodynamics of low-potential iron-sulfur proteins". Journal of Biological Inorganic Chemistry 5 6 (2000): 748-760. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033748454&partnerID=MN8TOARS.
  38. Macedo, A.L.; Rodrigues, P.; Goodfellow, B.J.. "The 3Fe containing ferredoxin from Desulfovibrio gigas: An NMR characterization of the oxidised and intermediate states". Coordination Chemistry Reviews 190-192 (1999): 871-881. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033303284&partnerID=MN8TOARS.
    10.1016/S0010-8545(99)00126-5
  39. Goodfellow, BJ. "The solution structure of a [3Fe-4S] ferredoxin: oxidised ferredoxin II from Desulfovibrio gigas". Journal of Biological Inorganic Chemistry 4 4 (1999): 421-430.
    10.1007/s007750050328
  40. Macedo, AL. "Characterization of a 7Fe ferredoxin isolated from the marine denitrifier Pseudomonas nautica strain 617: Spectroscopic and electrochemical studies". Biochemical and Biophysical Research Communications 229 2 (1996): 524-530.
    10.1006/bbrc.1996.1837
  41. Macedo AL; Moura I; Surerus KK; Papaefthymiou V; Liu MY; LeGall J; Münck E; Moura JJ. "Thiol/disulfide formation associated with the redox activity of the [Fe3S4] cluster of Desulfovibrio gigas ferredoxin II. 1H NMR and Mossbauer spectroscopic study.". (1994): http://europepmc.org/abstract/med/8132528.
  42. Moreno, C.; Macedo, A.L.; Moura, I.; Moura, J.J.G.; LeGall, J.. "Redox properties of Desulfovibrio gigas [Fe3S4] and [Fe4S4] ferredoxins and heterometal cubane-type clusters formed within the [Fe3S4] core. Square wave voltammetric studies". Journal of Inorganic Biochemistry 53 3 (1994): 219-234. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028237205&partnerID=MN8TOARS.
    10.1016/0162-0134(94)80006-5
  43. Macedo, A.L.; Moura, I.; Surerus, K.K.; Papaefthymiou, V.; Liu, M.-Y.; LeGall, J.; Munck, E.; Moura, J.J.G.. "Thiol/disulfide formation associated with the redox activity of the [Fe3S4] cluster of Desulfovibrio gigas ferredoxin II.1H NMR and Mossbauer spectroscopic study". Journal of Biological Chemistry 269 11 (1994): 8052-8058. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028365050&partnerID=MN8TOARS.
  44. MACEDO, AL. "2-DIMENSIONAL H-1-NMR STUDIES ON DESULFOVIBRIO-GIGAS FERREDOXINS - ASSIGNMENT OF THE IRON-SULFUR CLUSTER CYSTEINYL LIGAND PROTONS". Magnetic Resonance in Chemistry 31 (1993): S59-S67.
    10.1002/mrc.1260311313
  45. MACEDO, AL. "TEMPERATURE-DEPENDENT PROTON NMR INVESTIGATION OF THE ELECTRONIC-STRUCTURE OF THE TRINUCLEAR IRON CLUSTER OF THE OXIDIZED DESULFOVIBRIO-GIGAS FERREDOXIN-II". Inorganic Chemistry 32 7 (1993): 1101-1105.
    10.1021/ic00059a013
  46. Costa, C.; Macedo, A.; Moura, I.; Moura, J.J.G.; Le Gall, J.; Berlier, Y.; Liu, M.-Y.; Payne, W.J.. "Regulation of the hexaheme nitrite/nitric oxide reductase of Desulfovibrio desulfuricans, Wolinella succinogenes and Escherichia coli. A mass spectrometric study". FEBS Letters 276 1-2 (1990): 67-70. http://www.scopus.com/inward/record.url?eid=2-s2.0-0025678634&partnerID=MN8TOARS.
Capítulo de livro
  1. Linda Cerofolini; José Malanho Silva; Enrico Ravera; Marco Fragai; Anjos L. Macedo; Giacomo Parigi; Carlos F. G. C. Geraldes. "Paramagnetic NMR of Transition Metal Derivatives of Human Carbonic Anhydrase: Implications for Enzyme Catalysis and Sustainability". 2024.
    10.1142/9789811283215_0014
Livro
  1. Goodfellow, B.J.; Macedo, A.L.. Nmr Structural Studies Of Iron-Sulfur Proteins. 1999.
    10.1016/S0066-4103(08)60015-0
  2. Moura, J.J.G.; Macedo, A.L.; Palma, P.N.. Ferredoxins. 1994.
    10.1016/0076-6879(94)43014-4
Poster em conferência
  1. Carla S. B. Viegas; Carreira, Joana; Sara Dufour; Francis Impens; Anjos Macedo; António Matos; Simes, Dina. Autor correspondente: Carla S. B. Viegas. "Deciphering the complexity of extracellular vesicles (EVs) mediated vascular calcification using a proteomic approach". Trabalho apresentado em 2nd Joint Meeting of Spanish, French and Portuguese Proteomics Societies, 2022.

Outros

Empresa spin-off
  1. 2019. Nitrogen Sensing Solutions, Lda. Aquaculture; biosensors; water monitoring. https://www.nitrogensensing.com.
Outra produção
  1. Studies on the two mononuclear iron binding domains of Desulfoferrodoxin. 1999. C. S. Ascenso; Anjos L. Macedo; F. Rusnak; José J. G. Moura; I. Moura. https://novaresearch.unl.pt/en/publications/0710acbe-8215-48f9-ad8b-f4c583a74839.
Atividades

Orientação

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2018 - 2022 Ultra-high resolution structure determination of transition metal substituted human carbonic anhydrase 2 - inhibitor complexes
Orientador de José Pedro Malanho da Silva
 joint PhD in Chemistry (FCT-NOVA) and Structural Biology (Univ. Florence); the project aims to explore the potential of Cu(II) and Ni(II) as paramagnetic probes to obtain NMR and EPR observables in human Carbonic Anhydrase 2 (Doutoramento)
Universidade Nova de Lisboa - Faculdade de Ciências e Tecnologia, Portugal

REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal

Università degli Studi di Firenze, Itália
2016 - 2021 Development of point-of-care tests using enzyme (NiR & PON) based electrochemical biosensors
Coorientador
 PhD in Sustainable Chemistry (Doutoramento)
Universidade Nova de Lisboa - Faculdade de Ciências e Tecnologia, Portugal
2015 - 2017/03 Utilização de Nanopartículas Circulantes (Extracelulares) como Biomarcadores na Calcificação Vascular / Circulating Extracellular Nanoparticles as biomarkers in vascular Calcification
Orientador de Rute Miriam Santos Morais
 Master in Molecular Genetics and Biomedicine (Mestrado)
Universidade Nova de Lisboa - Faculdade de Ciências e Tecnologia, Portugal
2009 - 2012 Integrated study by NMR and X-ray Crystallography on the analysis of the molecular interactions in heme-binding proteins
Orientador de Freire, Filipe Miguel dos Santos
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2009 - 2012 Molecular determinants of ligand specificity in carbohydrate-binding modules: an NMR and X-ray crystallography integrated study
Coorientador
Universidade Nova de Lisboa - Faculdade de Ciências e Tecnologia, Portugal
2001 - 2007 NMR Studies of Murine Alas and Murine P22hbp: Two Proteins Involved in iron Metabolism
Orientador
 PhD in Biochemistry (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação) 		Instituição / Organização
2017/06/19 - 2017/06/23 First Hands-On Training School of the COST Action FeSBioNet, “Understanding the molecular mechanisms of Fe/S protein biogenesis”. COST Action CA 15133 (http://www.cost.eu/COST_Actions/ca/CA15133) (2017/06/19 - 2017/06/23)
Oficina (workshop) (Presidente da Comissão Organizadora)
 Universidade Nova de Lisboa - Faculdade de Ciências e Tecnologia, Portugal

Membro de comissão

Descrição da atividade
Tipo de participação 		Instituição / Organização
2016 - Atual Coordinator of the PhD Program in Biochemistry @ FCT-NOVA
Coordenador
 Universidade Nova de Lisboa - Faculdade de Ciências e Tecnologia, Portugal
2014 - Atual International PhD Program "NMR Applied to Chemistry, Materials and Biosciences" - Sponsor@FCT-UNL
Outro
 Universidade Nova de Lisboa - Faculdade de Ciências e Tecnologia, Portugal
2014 - Atual Dançar com Pk - a program of free dance classes for people with Parkinson Disease https://www.facebook.com/dancarcompk/
Coordenador
2013 - Atual Member of the Management Board - Portuguese Nuclear Magnetic Resonance Network (http://ptnmr.dq.ua.pt) PTNMR Mission: provide the scientific community with access to modern and up-to-date NMR spectrometers, housed in scientific institutions with competence and scientific expertise on the use of this type of equipment. The Portuguese NMR network was created with the support of the Portuguese Foundation for Science and Technology (FCT) in the frame of a national programme for acquisition and upgrading of scientific equipment.
Outro
2016/04/15 - 2020/10/14 - The Biogenesis of Iron-sulfur Proteins: from Cellular Biology to Molecular Aspects (FeSBioNet) COST Action CA 15133 (http://www.cost.eu/COST_Actions/ca/CA15133) Management Committee
Outro
 Universidade Nova de Lisboa - Faculdade de Ciências e Tecnologia, Portugal

REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2010/03 - 2014/03 Management Board Member of JPND (EU JPI for Neurodegenerative Diseases Research) - Portuguese representative http://www.neurodegenerationresearch.eu "The EU Joint Programme JPND – Neurodegenerative Disease Research is the largest global research initiative and ...a new collaborative approach ... in which countries come together to define a common vision, a strategic research agenda and a management structure, ... with the objective to increase coordinated investment between participating countries in research aimed at finding causes, developing...
Outro
Distinções

Outra distinção

2017 Prémio Roche - Teresa Azevedo 2017, best unpublished scientific research
2014 Prémio BPI Seniores 2014 - Projecto Dançar com Parkinson - coordenação em parceria com APDPk
2009 Executive Coordinator of the Scientific Council for Life and Health Sciences - FCT: Four years commission (2009-2012)
Fundação para a Ciência e a Tecnologia, Portugal