Michael Stock (8A1E-96C5-2F55)

Curriculum Vitae

Michael Stock

Michael Stock. Completed the Licence in Medicine in 2003 by Albert-Ludwigs-Universität Freiburg Abteilung für Medizinische Soziologie and Licence in Biology in 1997 by Friedrich-Alexander-Universität Erlangen-Nürnberg - Campus Nürnberg. Is Postdoc in Department of Internal Medicine 3, University Hospital Erlangen, Germany. Published 33 articles in journals. Participates and/or participated as Principal investigator in 1 project(s).

Identificação

Identificação pessoal

Nome completo: Michael Stock

Nomes de citação

Stock, Michael

Identificadores de autor

Ciência ID: 8A1E-96C5-2F55
ORCID iD: 0000-0002-3322-0961

Formação

	Grau	Classificação
1998 - 2003 Concluído	Medicine (Licence) Albert-Ludwigs-Universität Freiburg Abteilung für Medizinische Soziologie, Alemanha
1992 - 1997 Concluído	Biology (Licence) Friedrich-Alexander-Universität Erlangen-Nürnberg - Campus Nürnberg, Alemanha

Percurso profissional

Ciência

	Categoria Profissional Instituição de acolhimento	Empregador
2010 - Atual	Pós-doutorado (Investigação)	Department of Internal Medicine 3, University Hospital Erlangen, Germany, Alemanha

2005 - 2010	Pós-doutorado (Investigação)	Department of Experimental Medicine I, University of Erlangen-Nuremberg, Germany, Alemanha

2003 - 2005	Pós-doutorado (Investigação)	Albert-Ludwigs-Universität Freiburg Abteilung für Medizinische Soziologie, Alemanha

Projetos

Bolsa

	Designação	Financiadores
2019 - 2022	Die Rolle von Wif-1 und weiterer sezernierter Wnt-Inhibitoren bei der Kontrolle von Wnt-Signalwegen während der Osteophytenbildung DFG Investigador responsável University Hospital Erlangen, Alemanha	Em curso
2017 - 2018	Charakterisierung der Aggrekanasehemmung durch Ucma bei der Arthrose STAEDTLER Stiftung Investigador responsável University Hospital Erlangen, Alemanha	Concluído
2014 - 2017	Die Aufklärung des Knorpelproteins Ucma in degenerativen und entzündlichen Gelenkerkrankungen DFG Investigador responsável University Hospital Erlangen, Alemanha	Concluído
2013 - 2014	Hedgehog-Signale und der zelluläre Ursprung pathologischer Knochenneubildung bei entzündlichen Gelenk-erkrankungen ELAN Investigador responsável University Hospital Erlangen, Alemanha	Concluído
2007 - 2010	Aufklärung von Funktion und Regulation des extrazellulären Knorpelproteins RIK111 DFG Grant Investigador responsável	Concluído
2007 - 2010	Die Rolle des Wnt-Inhibitory Factors Wif-1 in der Entstehung und Stablisierung der Gelenkoberfläche IZKF Investigador responsável University Hospital Erlangen, Alemanha	Concluído

Produções

Publicações

Artigo em revista

Seuffert, Fritz; Weidner, Daniela; Baum, Wolfgang; Schett, Georg; Stock, Michael. "Upper zone of growth plate and cartilage matrix associated protein protects cartilage during inflammatory arthritis". Arthritis Research & Therapy 20 1 (2018): http://dx.doi.org/10.1186/s13075-018-1583-2.
Publicado • 10.1186/s13075-018-1583-2
Stock, Michael. "Defects in chondrocyte maturation and secondary ossification in mouse knee joint epiphyses due to Snorc deficiency.". Osteoarthritis and cartilage (2017): http://europepmc.org/abstract/med/28323137.
10.1016/j.joca.2017.03.010
Stock, Michael. "Corrigendum to "Fc-gamma receptors are not involved in cartilage damage during experimental osteoarthritis" [Osteoarthritis Cartilage 23 (2015) 1221-1225].". Osteoarthritis and cartilage (2017): http://europepmc.org/abstract/med/27865755.
10.1016/j.joca.2016.11.003
Stock, Michael. "A Dual Role of Upper Zone of Growth Plate and Cartilage Matrix-Associated Protein in Human and Mouse Osteoarthritic Cartilage: Inhibition of Aggrecanases and Promotion of Bone Turnover.". Arthritis & rheumatology (Hoboken, N.J.) (2017): http://europepmc.org/abstract/med/28086000.
10.1002/art.40042
Stock, Michael. "Inhibition of Notch1 promotes hedgehog signalling in a HES1-dependent manner in chondrocytes and exacerbates experimental osteoarthritis.". Annals of the rheumatic diseases (2016): http://europepmc.org/abstract/med/26851274.
10.1136/annrheumdis-2015-208420
Stock, Michael. "Rsk2 controls synovial fibroblast hyperplasia and the course of arthritis.". Annals of the rheumatic diseases (2016): http://europepmc.org/abstract/med/25414238.
10.1136/annrheumdis-2014-205618
Stock, Michael. "Inhibition of Osteoarthritis by Adipose-Derived Stromal Cells Overexpressing Fra-1 in Mice.". Arthritis & rheumatology (Hoboken, N.J.) (2016): http://europepmc.org/abstract/med/26361381.
10.1002/art.39425
Stock, Michael. "Fc-gamma receptors are not involved in cartilage damage during experimental osteoarthritis.". Osteoarthritis and cartilage (2015): http://europepmc.org/abstract/med/25748082.
10.1016/j.joca.2015.02.019
Stock, Michael. "Dual pathways to endochondral osteoblasts: a novel chondrocyte-derived osteoprogenitor cell identified in hypertrophic cartilage.". Biology open (2015): http://europepmc.org/abstract/med/25882555.
10.1242/bio.201411031
Stock, Michael. "Sclerostin inhibition reverses systemic, periarticular and local bone loss in arthritis.". Annals of the rheumatic diseases (2013): http://europepmc.org/abstract/med/23666928.
10.1136/annrheumdis-2013-203345
Stock, Michael. "Wnt inhibitory factor 1 deficiency uncouples cartilage and bone destruction in tumor necrosis factor a-mediated experimental arthritis.". Arthritis and rheumatism (2013): http://europepmc.org/abstract/med/23784913.
10.1002/art.38054
Stock, Michael. "PPARß/d governs Wnt signaling and bone turnover.". Nature medicine (2013): http://europepmc.org/abstract/med/23542786.
10.1038/nm.3146
Stock, Michael. "RSK2 protects mice against TNF-induced bone loss.". Journal of cell science (2012): http://europepmc.org/abstract/med/22344264.
10.1242/jcs.096008
Stock, Michael. "The Wnt antagonist Wif-1 interacts with CTGF and inhibits CTGF activity.". Journal of cellular physiology (2012): http://europepmc.org/abstract/med/21928342.
10.1002/jcp.22957
Stock, Michael. "Ucma is not necessary for normal development of the mouse skeleton.". Bone (2012): http://europepmc.org/abstract/med/22155508.
10.1016/j.bone.2011.11.017
Stock, Michael. "Blockade of the hedgehog pathway inhibits osteophyte formation in arthritis.". Annals of the rheumatic diseases (2012): http://europepmc.org/abstract/med/22233602.
10.1136/ard.2010.148262
Stock, Michael. "R-spondin 1 protects against inflammatory bone damage during murine arthritis by modulating the Wnt pathway.". Arthritis and rheumatism (2010): http://europepmc.org/abstract/med/20506554.
10.1002/art.27496
Stock, Michael. "Stable subclones of the chondrogenic murine cell line MC615 mimic distinct stages of chondrocyte differentiation.". Journal of cellular biochemistry (2009): http://europepmc.org/abstract/med/19670270.
10.1002/jcb.22290
Stock, Michael. "Wif-1 is expressed at cartilage-mesenchyme interfaces and impedes Wnt3a-mediated inhibition of chondrogenesis.". Journal of cell science (2009): http://europepmc.org/abstract/med/19755491.
10.1242/jcs.048926
Stock, Michael. "Ucma, a novel secreted cartilage-specific protein with implications in osteogenesis.". The Journal of biological chemistry (2008): http://europepmc.org/abstract/med/18156182.
10.1074/jbc.m702792200
Stock, Michael. "Ucma--A novel secreted factor represents a highly specific marker for distal chondrocytes.". Matrix biology : journal of the International Society for Matrix Biology (2008): http://europepmc.org/abstract/med/17707622.
10.1016/j.matbio.2007.07.004
Stock, Michael. "Inhibitors of DNA methylation and histone deacetylation independently relieve AML1/ETO-mediated lysozyme repression.". Journal of leukocyte biology (2006): http://europepmc.org/abstract/med/17000900.
10.1189/jlb.0106005
Stock, Michael. "Twisted gastrulation modulates bone morphogenetic protein-induced collagen II and X expression in chondrocytes in vitro and in vivo.". The Journal of biological chemistry (2006): http://europepmc.org/abstract/med/16905550.
10.1074/jbc.m603419200
Stock, Michael. "Gene deregulation in gastric cancer.". Gene (2005): http://europepmc.org/abstract/med/16154715.
10.1016/j.gene.2005.06.026
Stock, Michael. "Control of RUNX2 isoform expression: the role of promoters and enhancers.". Journal of cellular biochemistry (2005): http://europepmc.org/abstract/med/15838892.
10.1002/jcb.20471
Stock, Michael. "Williams-Beuren syndrome critical region-5/non-T-cell activation linker: a novel target gene of AML1/ETO.". Oncogene (2004): http://europepmc.org/abstract/med/15489901.
10.1038/sj.onc.1208042
Stock, Michael. "Simplified method for gene targeting vector construction.". BioTechniques (2004): http://europepmc.org/abstract/med/15560127.
Stock, Michael. "Identification of novel genes of the bone-specific transcription factor Runx2.". Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research (2004): http://europepmc.org/abstract/med/15190888.
10.1359/jbmr.2004.19.6.959
Stock, Michael. "Absence of somatic mutations within the Runt domain of AML2/RUNX3 in acute myeloid leukaemia.". Leukemia (2003): http://europepmc.org/abstract/med/12886262.
10.1038/sj.leu.2403007
Stock, Michael. "Upstream and downstream targets of RUNX proteins.". Journal of cellular biochemistry (2003): http://europepmc.org/abstract/med/12682904.
10.1002/jcb.10491
Stock, Michael. "Expression of galectin-3 in skeletal tissues is controlled by Runx2.". The Journal of biological chemistry (2003): http://europepmc.org/abstract/med/12604608.
10.1074/jbc.m207631200
Stock, Michael. "Genomic characterization of the RUNX2 gene of Fugu rubripes.". Gene (2002): http://europepmc.org/abstract/med/12095689.
10.1016/s0378-1119(02)00592-9
Stock, Michael. "Mutation analysis of core binding factor A1 in patients with cleidocranial dysplasia.". American journal of human genetics (1999): http://europepmc.org/abstract/med/10521292.
10.1086/302622