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João C Fernandes. Concluiu o(a) Doutoramento em Biotecnologia em 2010/12/22 pelo(a) Universidade do Porto Faculdade de Farmácia e Doutoramento em Biotecnologia em 2010/12/22 pelo(a) Universidade Católica Portuguesa Escola Superior de Biotecnologia. Publicou 82 artigos em revistas especializadas. Possui 2 livro(s).
Identificação

Identificação pessoal

Nome completo
João C Fernandes

Nomes de citação

  • Fernandes, João

Identificadores de autor

Ciência ID
881D-7FFD-DD7D
ORCID iD
0000-0003-1556-1698
Scopus Author Id
35274726800

Websites

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Formação
Grau Classificação
2010/12/22
Concluído
 Biotecnologia (Doutoramento)
Especialização em Especialidade: Engenharia Bioquímica
Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal

Universidade do Porto Faculdade de Farmácia, Portugal
"Characterization of Commercial Bioactive Chitooligosaccharides" (TESE/DISSERTAÇÃO)
2010
Concluído
 Biotechnology - specialization in Biochemical Engineering (Doutoramento)
Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal

Universidade do Porto Faculdade de Farmácia, Portugal
"Characterization of commercial bioactive chitooligosaccharides" (TESE/DISSERTAÇÃO)
 Aprovado por Unanimidade
2005
Concluído
 BSc. Microbiology degree (Licenciatura)
Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal
"The bactericidal effect of wine on Listeria innocua in a stomach model system" (TESE/DISSERTAÇÃO)
 15
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2018/07 - Atual Investigador principal (carreira) (Investigação) Amyris Biotechnologies Inc, Estados Unidos
Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal
2017 - 2018/07 Investigador Auxiliar (carreira) (Investigação) Universidade Católica Portuguesa, Portugal
Portuguesa Centro de Biotecnologia e Química Fina, Portugal
2012/01 - 2013 Pós-doutorado (Investigação) Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
(...)
2011/01 - 2011/12 Pós-doutorado (Investigação) Universidade de Coimbra Faculdade de Medicina, Portugal
Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal

Outros

Categoria Profissional
Instituição de acolhimento 		Empregador
2015 - 2017 Team leader for Janssen Biologics and Abbvie drug discovery for rheumatoid arthritis projects Barts and The London School of Medicine and Dentistry William Harvey Research Institute, Reino Unido
Barts and The London School of Medicine and Dentistry William Harvey Research Institute, Reino Unido
2013 - 2015 Researcher and Project Developer FairJourney Biologics SA, Portugal
Projetos

Bolsa

Designação Financiadores
2021/10/15 - 2022/02/14 GastroCure - Bioactive Soybean and Cruciferous extracts towards application in gastrointestinal disorders: development, characterization and delivery
PTDC/BAA-AGR/32094/2017
Universidade Católica Portuguesa, Portugal

Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2012/01/01 - 2013/09/30 REGULATION OF ERYTHROPOIETIN GENE EXPRESSION IN NON-RENAL TISSUES
info:eu-repo/grantAgreement/FCT/SFRH/SFRH2%FBPD2%F819682%F2011/PT
Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal
 Universidade do Algarve Faculdade de Ciências e Tecnologia
Concluído
2011/01/01 - 2011/12/31 Relationship between chronic renal failure, inflammation and erythropoiesis in the resistance to rhEPO therapy
PTDC/SAL-TOX/114253/2009
Bolseiro de Pós-Doutoramento
Concluído
2007/02/01 - 2010/12/22 PRODUCTION AND CHARACTERIZATION OF BIOACTIVE CHITOOLIGOSACCHARIDES
info:eu-repo/grantAgreement/FCT/SFRH/SFRH2%FBD2%F310872%F2006/PT
Portuguesa Centro de Biotecnologia e Química Fina, Portugal
 Universidade do Algarve Faculdade de Ciências e Tecnologia

Projeto

Designação Financiadores
2018/01/01 - Atual ALCHEMY - : Capturing High Value from Industrial Fermentation BioProduct
POCI-01-0247-FEDER-027578
Lead Senior Researcher
Em curso
2020/11/01 - 2023/07/31 unCOVer - Leveraging real-world data for rapid evidence-based response to COVID-19
101016216
Investigador
Em curso
2021/04/01 - 2022/10/31 Amyris HandCare Project COVID19
POCI-01-02B7-FEDER-062592
Investigador
2020/03/01 - 2022/08/31 GluVac – Explorar o potencial de ß-glucanas como adjuvantes imunológicos no desenvolvimento de vacinas para a Covid-19
POCI-01-02B7-FEDER-059949
Investigador responsável
Autoridade de Gestão do Programa Operacional Competitividade e Internacionalização
2020/03 - 2022/08 GluVac ¿ Explorar o potencial de ß-glucanas como adjuvantes imunológicos no desenvolvimento de vacinas para a Covid-19
ID 59949
 Autoridade de Gestão do Programa Operacional Competitividade e Internacionalização
2013/10/01 - 2015/09/30 BNaive Fab Humanos .: Construção de uma biblioteca naïve de fragmentos Fab humanos e isolamento de Fabs anti-CXCR4
NORTE-01-0247-FEDER-011431
Investigador responsável
2005/09/01 - 2007/01/01 BIOTEX project - Bioactive Textiles using functional biopolymers
POCTI/CTM/58312/2004
Bolseiro de Investigação
Portuguesa Centro de Biotecnologia e Química Fina, Portugal
 Associação para a Inovação e Desenvolvimento da FCT
Concluído

Outro

Designação Financiadores
2015/10/01 - 2017/05/31 Janssen Biologics and Abbvie internal projects related with biologic drug discovery
Pharma private funds
Investigador responsável
2009/01/01 - 2010/12/22 QUITORAL- Development of new oral medical formulations based on chitosans.
QREN - ADI 3474
Outra
Portuguesa Centro de Biotecnologia e Química Fina, Portugal
Concluído
Produções

Publicações

Artigo em conferência
  1. Ribeiro, Sandra; Garrido, Patrícia; Fernandes, João; Vala, Helena; Rocha-Pereira, Petronila; Costa, Elísio; Belo, Luís; Reis, Flávio; Santos-Silva, Alice. "Impaired renal endothelial nitric oxide synthase and reticulocyte production as modulators of hypertension induced by recombinant human erythropoietin in the rat". 2016.
    10.1093/ndt/gfw158
  2. Ribeiro, Sandra; Garrido, Patrícia; Fernandes, João; Rocha, Susana; Vala, Helena; Rocha-Pereira, Petronila; Belo, Luís; Reis, Flávio; Santos-Silva, Alice. "Efeitos de Diferentes Doses de Eritropoietina Recombinante Humana num Modelo Animal de Anemia na Doença Renal Crónica". 2016.
  3. Ribeiro, Sandra; Garrido, Patrícia; Fernandes, João; Vala, Helena; Rocha-Pereira, Petronila; Costa, Elísio; Belo, Luís; Reis, Flávio; Santos-Silva, Alice. "Inflammatory and hematological disturbances associated with resistance to recombinant human erythropoietin therapy in CKD anemia in a rat model". 2016.
  4. Ribeiro, Sandra; Garrido, Patrícia; Fernandes, João; Costa, Elísio; Belo, Luís; Reis, Flávio; Santos- Silva, Alice; Vala, Helena. "Recombinant human erythropoietin treatment in a rat model of nephrectomy". 2015.
    Publicado
Artigo em revista
  1. Pedro Sousa; Diana Tavares-Valente; Carla F. Pereira; Ines Pinto-Ribeiro; Azevedo-Silva, J.; Madureira A. R.; Oscar L Ramos; et al. "Circular economyeast". International Journal of Biological Macromolecules 265 part 2 (2024): https://ciencia.ucp.pt/en/publications/7fcc2320-6f16-47dd-bcf9-a37485bbc2de.
    10.1016/j.ijbiomac.2024.130933
  2. Maria João Carvalho; Sílvia Santos Pedrosa; Adélia Mendes; Azevedo-Silva, J.; Fernandes JC; Pintado, M.; Ana Lúcia Silva Oliveira; Madureira A. R.. "Anti-aging potential of a novel ingredient derived from sugarcane straw extract (SSE)". International Journal of Molecular Sciences 25 1 (2024): https://ciencia.ucp.pt/en/publications/16bf5c9c-7c77-4b1d-858b-6ba199f4824d.
    10.3390/ijms25010021
  3. Pedro Sousa; Diana Tavares-Valente; Manuela Amorim; Azevedo-Silva, J.; Pintado, M.; Fernandes JC. "ß-Glucan extracts as high-value multifunctional ingredients for skin health". Carbohydrate Polymers 322 (2023): https://ciencia.ucp.pt/en/publications/b6275d90-0da6-4029-83f3-6f2ca1b614b4.
    10.1016/j.carbpol.2023.121329
  4. Casanova, Francisca; Carla F. Pereira; Alessandra Braga Ribeiro; Pedro João Miranda de Castro; R. Freixo; Eva Martins; Diana Tavares-Valente; et al. "Biological potential and bioaccessibility of encapsulated curcumin into cetyltrimethylammonium bromide modified cellulose nanocrystals". Pharmaceuticals 16 12 (2023): https://ciencia.ucp.pt/en/publications/b0f43775-7f80-4265-9857-5942fb45b657.
    10.3390/ph16121737
  5. GBD 2019 IMID Collaborators; Dongze Wu; Yingzhao Jin; Yuhan Xing; Melsew Dagne Abate; Mohammadreza Abbasian; Mohsen Abbasi-Kangevari; et al. "Global, regional, and national incidence of six major immune-mediated inflammatory diseases". EClinicalMedicine 64 (2023): https://ciencia.ucp.pt/en/publications/bb3f96f0-cce6-497f-a18f-1dbad23a34f8.
    10.1016/j.eclinm.2023.102193
  6. Marco Duarte; Maria João Carvalho; Nelson Mota de Carvalho; Azevedo-Silva, J.; Adélia Mendes; Inês Pinto Ribeiro; Fernandes JC; et al. "Skincare potential of a sustainable postbiotic extract produced through sugarcane straw fermentation by saccharomyces cerevisiae". BioFactors 49 5 (2023): 1038-1060. https://ciencia.ucp.pt/en/publications/ad60315e-f2a9-41de-a76e-13a1ac417cc5.
    10.1002/biof.1975
  7. Joana R. Costa; Tânia Neto; Sílvia Santos Pedrosa; Sérgio Sousa; Azevedo-Silva, J.; Diana Tavares-Valente; Adélia Mendes; et al. "Biogenic silica microparticles as a new and sustainable cosmetic ingredient". Colloids and Surfaces B: Biointerfaces 226 (2023): https://ciencia.ucp.pt/en/publications/ad3df084-ee99-44db-b75a-93926ddf2176.
    10.1016/j.colsurfb.2023.113305
  8. Casanova, Francisca; Carla F. Pereira; Alessandra Braga Ribeiro; Eduardo Costa; R. Freixo; Pedro M. Castro; Fernandes JC; Pintado, M.; Oscar L Ramos. "Design of innovative biocompatible cellulose nanostructures for the delivery and sustained release of curcumin". Pharmaceutics 15 3 (2023): https://ciencia.ucp.pt/en/publications/14a07d7f-d38a-46e3-b4fd-30648ab0e590.
    10.3390/pharmaceutics15030981
  9. Mariana Luz-Veiga; Manuela Amorim; Inês Pinto-Ribeiro; Ana L. S. Oliveira; Sara Silva; Lígia Pimentel; Rodriguez-Alcalá, L.M.; et al. "Cannabidiol and cannabigerol exert antimicrobial activity without compromising skin microbiota". International Journal of Molecular Sciences 24 3 (2023): https://ciencia.ucp.pt/en/publications/bbfb4d43-d105-425b-992c-271d6d0f84f8.
    10.3390/ijms24032389
  10. Mariana Luz-Veiga; Azevedo-Silva, J.; Fernandes JC. "Beyond pain relief". Pharmaceuticals 16 2 (2023): https://ciencia.ucp.pt/en/publications/361b3441-5b1e-4450-9566-82507904ef68.
    10.3390/ph16020155
  11. Cláudia Castro; Ines Pinto-Ribeiro; Isabel Pereira; Maria João Carvalho; Claudia Popov; Diana Tavares-Valente; Helene R. Moreira; et al. "The multidisciplinary process of developing an alcohol- based hand sanitizer from scratch". Journal of Cosmetic Science 74 1 (2023): 44-62. https://ciencia.ucp.pt/en/publications/4744a41f-c3bc-47a9-941f-c0cc16065d57.
  12. GBD 2019 Antimicrobial Resistance Collaborators; Kevin S. Ikuta; Lucien R. Swetschinski; Gisela Robles Aguilar; Fablina Sharara; Tomislav Mestrovic; Authia P. Gray; et al. "Global mortality associated with 33 bacterial pathogens in 2019". The Lancet 400 10369 (2022): 2221-2248. https://ciencia.ucp.pt/en/publications/b1b67f8d-4065-4d22-90d2-f556b4932a10.
    10.1016/S0140-6736(22)02185-7
  13. "Bioactivity and Bioaccessibility of Bioactive Compounds in Gastrointestinal Digestion of Tomato Bagasse Extracts". Foods 11 7 (2022): 1064-1064. http://dx.doi.org/10.3390/foods11071064.
    10.3390/foods11071064
  14. Mendes, Adélia; Azevedo-Silva, João; Fernandes, João. "From Sharks to Yeasts: Squalene in the Development of Vaccine Adjuvants". Pharmaceuticals 15 3 (2022): 265. http://dx.doi.org/10.3390/ph15030265.
    10.3390/ph15030265
  15. Casanova, F.; Pereira, C.F.; Ribeiro, A.B.; Freixo, R.; Costa, E.; Pintado, M.E.; Fernandes, J.C.; Ramos, Ó.L.. "Novel micro-and nanocellulose-based delivery systems for liposoluble compounds". Nanomaterials 11 10 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85116528799&partnerID=MN8TOARS.
    10.3390/nano11102593
  16. Peñalvo, J.L.; Mertens, E.; Ademovic, E.; Akgun, S.; Baltazar, A.L.; Buonfrate, D.; G Oklo, M.; et al. "Unravelling data for rapid evidence-based response to COVID-19: A summary of the unCoVer protocol". BMJ Open 11 11 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85120371425&partnerID=MN8TOARS.
    10.1136/bmjopen-2021-055630
  17. Rocha, S.; Valente, M.J.; Coimbra, S.; Catarino, C.; Rocha-Pereira, P.; Oliveira, J.G.; Madureira, J.; et al. "Interleukin 6 (rs1800795) and pentraxin 3 (rs2305619) polymorphisms-association with inflammation and all-cause mortality in end-stage-renal disease patients on dialysis". Scientific Reports 11 1 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85111081363&partnerID=MN8TOARS.
    10.1038/s41598-021-94075-x
  18. Galles, N.C.; Liu, P.Y.; Updike, R.L.; Fullman, N.; Nguyen, J.; Rolfe, S.; Sbarra, A.N.; et al. "Measuring routine childhood vaccination coverage in 204 countries and territories, 1980–2019: a systematic analysis for the Global Burden of Disease Study 2020, Release 1". The Lancet 398 10299 (2021): 503-521. http://www.scopus.com/inward/record.url?eid=2-s2.0-85110301351&partnerID=MN8TOARS.
    10.1016/S0140-6736(21)00984-3
  19. Teixeira, F.S.; Vidigal, S.S.M.P.; Pimentel, L.L.; Costa, P.T.; Tavares-valente, D.; Azevedo-silva, J.; Pintado, M.E.; Fernandes, J.C.; Rodríguez-alcalá, L.M.. "Phytosterols and novel triterpenes recovered from industrial fermentation coproducts exert in vitro anti-inflammatory activity in macrophages". Pharmaceuticals 14 6 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85108866914&partnerID=MN8TOARS.
    10.3390/ph14060583
  20. Fernandes, João. "Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017". Nature Medicine (2020): http://dx.doi.org/10.1038/s41591-020-0807-6.
    10.1038/s41591-020-0807-6
  21. Alatab, S.; Sepanlou, S.G.; Ikuta, K.; Vahedi, H.; Bisignano, C.; Safiri, S.; Sadeghi, A.; et al. "The global, regional, and national burden of inflammatory bowel disease in 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017". The Lancet Gastroenterology and Hepatology 5 1 (2020): 17-30. http://www.scopus.com/inward/record.url?eid=2-s2.0-85075968413&partnerID=MN8TOARS.
    10.1016/S2468-1253(19)30333-4
  22. Etemadi, A.; Safiri, S.; Sepanlou, S.G.; Ikuta, K.; Bisignano, C.; Shakeri, R.; Amani, M.; et al. "The global, regional, and national burden of stomach cancer in 195 countries, 1990–2017: a systematic analysis for the Global Burden of Disease study 2017". The Lancet Gastroenterology and Hepatology 5 1 (2020): 42-54. http://www.scopus.com/inward/record.url?eid=2-s2.0-85075908310&partnerID=MN8TOARS.
    10.1016/S2468-1253(19)30328-0
  23. Bikbov, B.; Purcell, C.A.; Levey, A.S.; Smith, M.; Abdoli, A.; Abebe, M.; Adebayo, O.M.; et al. "Global, regional, and national burden of chronic kidney disease, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017". The Lancet 395 10225 (2020): 709-733. http://www.scopus.com/inward/record.url?eid=2-s2.0-85079872533&partnerID=MN8TOARS.
    10.1016/S0140-6736(20)30045-3
  24. Kinyoki, D.K.; Ross, J.M.; Lazzar-Atwood, A.; Munro, S.B.; Schaeffer, L.E.; Abbasalizad-Farhangi, M.; Abbasi, M.; et al. "Author Correction: Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017 (Nature Medicine, (2020), 26, 5, (750-759), 10.1038/s41591-020-0807-6)". Nature Medicine 26 8 (2020): 1308-1308. http://www.scopus.com/inward/record.url?eid=2-s2.0-85087382046&partnerID=MN8TOARS.
    10.1038/s41591-020-0972-7
  25. Safiri, S.; Sepanlou, S.G.; Ikuta, K.S.; Bisignano, C.; Salimzadeh, H.; Delavari, A.; Ansari, R.; et al. "The global, regional, and national burden of colorectal cancer and its attributable risk factors in 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017". The Lancet Gastroenterology and Hepatology 4 12 (2019): 913-933. http://www.scopus.com/inward/record.url?eid=2-s2.0-85074240207&partnerID=MN8TOARS.
    10.1016/S2468-1253(19)30345-0
  26. Coimbra, S.; Reis, F.; Nunes, S.; Viana, S.; Valente, M.J.; Rocha, S.; Catarino, C.; et al. "The protective role of adiponectin for lipoproteins in end-stage renal disease patients: Relationship with diabetes and body mass index". Oxidative Medicine and Cellular Longevity 2019 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85062598052&partnerID=MN8TOARS.
    10.1155/2019/3021785
  27. Burstein, R.; Henry, N.J.; Collison, M.L.; Marczak, L.B.; Sligar, A.; Watson, S.; Marquez, N.; et al. "Mapping 123 million neonatal, infant and child deaths between 2000 and 2017". Nature 574 7778 (2019): 353-358. http://www.scopus.com/inward/record.url?eid=2-s2.0-85073458638&partnerID=MN8TOARS.
    10.1038/s41586-019-1545-0
  28. Afshin, A.; Sur, P.J.; Fay, K.A.; Cornaby, L.; Ferrara, G.; Salama, J.S.; Mullany, E.C.; et al. "Health effects of dietary risks in 195 countries, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017". The Lancet 393 10184 (2019): 1958-1972. http://www.scopus.com/inward/record.url?eid=2-s2.0-85065230885&partnerID=MN8TOARS.
    10.1016/S0140-6736(19)30041-8
  29. Belo, L.; Rocha, S.; Valente, M.J.; Coimbra, S.; Catarino, C.; Bronze-da-Rocha, E.; Rocha-Pereira, P.; et al. "Hepcidin and diabetes are independently related with soluble transferrin receptor levels in chronic dialysis patients". Renal failure 41 1 (2019): 662-672. http://www.scopus.com/inward/record.url?eid=2-s2.0-85070480055&partnerID=MN8TOARS.
    10.1080/0886022X.2019.1635893
  30. Valente, M.J.; Rocha, S.; Coimbra, S.; Catarino, C.; Rocha-Pereira, P.; Bronze-Da-Rocha, E.; Oliveira, J.G.; et al. "Long pentraxin 3 as a broader biomarker for multiple risk factors in end-stage renal disease: Association with all-cause mortality". Mediators of Inflammation 2019 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85069797521&partnerID=MN8TOARS.
    10.1155/2019/3295725
  31. Stanaway, J.D.; Afshin, A.; Gakidou, E.; Lim, S.S.; Abate, D.; Abate, K.H.; Abbafati, C.; et al. "Erratum: Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017 (The Lancet (2018) 392(10159) (1923–1994), (S0140673618322256), (10.1016/S0140-6736(18)32225-6))". The Lancet 393 10190 (2019): e44-e44. http://www.scopus.com/inward/record.url?eid=2-s2.0-85067299595&partnerID=MN8TOARS.
    10.1016/S0140-6736(19)31429-1
  32. Fernandes, J.C.. "Therapeutic application of antibody fragments in autoimmune diseases: current state and prospects". Drug Discovery Today 23 12 (2018): 1996-2002. http://www.scopus.com/inward/record.url?eid=2-s2.0-85048582382&partnerID=MN8TOARS.
    10.1016/j.drudis.2018.06.003
  33. Lozano, R.; Fullman, N.; Abate, D.; Abay, S.M.; Abbafati, C.; Abbasi, N.; Abbastabar, H.; et al. "Measuring progress from 1990 to 2017 and projecting attainment to 2030 of the health-related Sustainable Development Goals for 195 countries and territories: a systematic analysis for the Global Burden of Disease Study 2017". The Lancet 392 10159 (2018): 2091-2138. http://www.scopus.com/inward/record.url?eid=2-s2.0-85056168651&partnerID=MN8TOARS.
    10.1016/S0140-6736(18)32281-5
  34. Fullman, N.; Yearwood, J.; Abay, S.M.; Abbafati, C.; Abd-Allah, F.; Abdela, J.; Abdelalim, A.; et al. "Measuring performance on the Healthcare Access and Quality Index for 195 countries and territories and selected subnational locations: A systematic analysis from the Global Burden of Disease Study 2016". The Lancet 391 10136 (2018): 2236-2271. http://www.scopus.com/inward/record.url?eid=2-s2.0-85047728707&partnerID=MN8TOARS.
    10.1016/S0140-6736(18)30994-2
  35. Roth, G.A.; Johnson, C.O.; Abate, K.H.; Abd-Allah, F.; Ahmed, M.; Alam, K.; Alam, T.; et al. "The burden of cardiovascular diseases among us states, 1990-2016". JAMA Cardiology 3 5 (2018): 375-389. http://www.scopus.com/inward/record.url?eid=2-s2.0-85049079307&partnerID=MN8TOARS.
    10.1001/jamacardio.2018.0385
  36. Roth, G.A.; Abate, D.; Abate, K.H.; Abay, S.M.; Abbafati, C.; Abbasi, N.; Abbastabar, H.; et al. "Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980–2017: a systematic analysis for the Global Burden of Disease Study 2017". The Lancet 392 10159 (2018): 1736-1788. http://www.scopus.com/inward/record.url?eid=2-s2.0-85056166310&partnerID=MN8TOARS.
    10.1016/S0140-6736(18)32203-7
  37. Roth, G.A.; Abate, D.; Abate, K.H.; Abay, S.M.; Abbafati, C.; Abbasi, N.; Abbastabar, H.; et al. "Erratum: Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980–2017: a systematic analysis for the Global Burden of Disease Study 2017 (The Lancet (2018) 392(10159) (1736–1788)(S0140673618322037)(10.1016/S0140-6736(18)32203-7))". The Lancet 392 10160 (2018): 2170-2170. http://www.scopus.com/inward/record.url?eid=2-s2.0-85057157683&partnerID=MN8TOARS.
    10.1016/S0140-6736(18)32833-2
  38. Fernandes, João; Fullman, N.; Barber, R.M.; Abajobir, A.A.; Abate, K.H.; Abbafati, C.; Abbas, K.M.; et al. "Measuring progress and projecting attainment on the basis of past trends of the health-related Sustainable Development Goals in 188 countries: an analysis from the Global Burden of Disease Study 2016.". Lancet (London, England) 390 10106 (2017): e38-e38. http://europepmc.org/abstract/med/28916366.
    10.1016/s0140-6736(17)32336-x
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  95. Campos, D.A.; Ribeiro, A.C.; Costa, E.M.; Fernandes, J.C.; Tavaria, F.K.; Araruna, F.B.; Eiras, C.; et al. "Study of antimicrobial activity and atomic force microscopy imaging of the action mechanism of cashew tree gum". Carbohydrate Polymers 90 1 (2012): 270-274. http://www.scopus.com/inward/record.url?eid=2-s2.0-84864132325&partnerID=MN8TOARS.
    10.1016/j.carbpol.2012.05.034
  96. Fernandes, J.C.; Sereno, J.; Garrido, P.; Parada, B.; Cunha, M.F.X.; Reis, F.; Pintado, M.E.; Santos-Silva, A.. "Inhibition of bladder tumor growth by chitooligosaccharides in an experimental carcinogenesis model". Marine Drugs 10 12 (2012): 2661-2675. http://www.scopus.com/inward/record.url?eid=2-s2.0-84871733767&partnerID=MN8TOARS.
    10.3390/md10122661
  97. Costa, E.; Coimbra, J.; Catarino, C.; Ribeiro, S.; Reis, F.; Nascimento, H.; Fernandes, J.; et al. "Major determinants of BMP-2 serum levels in hemodialysis patients". Renal Failure 34 10 (2012): 1355-1358. http://www.scopus.com/inward/record.url?eid=2-s2.0-84867720386&partnerID=MN8TOARS.
    10.3109/0886022X.2012.725289
  98. Borges, Ana; Borges, Margarida; Fernandes, João; Nascimento, Henrique; Sameiro-Faria, Maria; Miranda, Vasco; Reis, Flávio; et al. "Apoptosis of Peripheral CD4+T-Lymphocytes in End-Stage Renal Disease Patients Under Hemodialysis and rhEPO Therapies". Renal Failure 33 2 (2011): 138-143. http://dx.doi.org/10.3109/0886022x.2011.553300.
    10.3109/0886022x.2011.553300
  99. Borges, A.; Borges, M.; Fernandes, J.; Nascimento, H.; Sameiro-Faria, M.; Miranda, V.; Reis, F.; et al. "Apoptosis of peripheral CD4++ T-lymphocytes in end-stage renal disease patients under hemodialysis and rhEPO therapies". Renal Failure 33 2 (2011): 138-143. http://www.scopus.com/inward/record.url?eid=2-s2.0-79952000251&partnerID=MN8TOARS.
    10.3109/0886022X.2011.553300
  100. Marques, M.; Brown, S.A.; Rodrigues-Pereira, P.; Natália, M.; Cordeiro, D.S.; Morales-Helguera, A.; Cobrado, L.; et al. "Animal model of implant capsular contracture: Effects of chitosan". Aesthetic Surgery Journal 31 5 (2011): 540-550. http://www.scopus.com/inward/record.url?eid=2-s2.0-79960195845&partnerID=MN8TOARS.
    10.1177/1090820X11411475
  101. Fernandes, J.C.; Borges, M.; Nascimento, H.; Bronze-da-Rocha, E.; Ramos, O.S.; Pintado, M.E.; Malcata, F.X.; Santos-Silva, A.. "Cytotoxicity and genotoxicity of chitooligosaccharides upon lymphocytes". International Journal of Biological Macromolecules 49 3 (2011): 433-438. http://www.scopus.com/inward/record.url?eid=2-s2.0-79959590540&partnerID=MN8TOARS.
    10.1016/j.ijbiomac.2011.05.032
  102. Fernandes, J.C.; Spindola, H.; De Sousa, V.; Santos-Silva, A.; Pintado, M.E.; Malcata, F.X.; Carvalho, J.E.. "Anti-inflammatory activity of chitooligosaccharides in vivo". Marine Drugs 8 6 (2010): 1763-1768. http://www.scopus.com/inward/record.url?eid=2-s2.0-77954239729&partnerID=MN8TOARS.
    10.3390/md8061763
  103. Paiva-Martins, F.; Fernandes, J.; Santos, V.; Silva, L.; Borges, F.; Rocha, S.; Belo, L.; Santos-Silva, A.. "Powerful protective role of 3,4-dihydroxyphenylethanol-elenolic acid dialdehyde against erythrocyte oxidative-Lnduced hemolysis". Journal of Agricultural and Food Chemistry 58 1 (2010): 135-140. http://www.scopus.com/inward/record.url?eid=2-s2.0-75249107679&partnerID=MN8TOARS.
    10.1021/jf9031052
  104. Nascimento, H.; Belo, L.; Fernandes, J.; Rocha, S.; Quintanilha, A.; Santos-Silva, A.. "In vitro studies with 'acatalasemic-like' erythrocytes and hydrogen peroxide: Attention to the formation of lysis resistant erythrocytes". International Journal of Laboratory Hematology 32 1 PART.2 (2010): 127-131. http://www.scopus.com/inward/record.url?eid=2-s2.0-77449106840&partnerID=MN8TOARS.
    10.1111/j.1751-553X.2008.01129.x
  105. Gião, M.S.; Leitão, I.; Pereira, A.; Borges, A.B.; Guedes, C.J.; Fernandes, J.C.; Belo, L.; et al. "Plant aqueous extracts: Antioxidant capacity via haemolysis and bacteriophage P22 protection". Food Control 21 5 (2010): 633-638. http://www.scopus.com/inward/record.url?eid=2-s2.0-73549116726&partnerID=MN8TOARS.
    10.1016/j.foodcont.2009.08.014
  106. Fernandes, J.C.; Eaton, P.; Nascimento, H.; Gião, M.S.; Ramos, O.S.; Belo, L.; Santos-Silva, A.; Pintado, M.E.; Malcata, F.X.. "Antioxidant activity of chitooligosaccharides upon two biological systems: Erythrocytes and bacteriophages". Carbohydrate Polymers 79 4 (2010): 1101-1106. http://www.scopus.com/inward/record.url?eid=2-s2.0-73649087900&partnerID=MN8TOARS.
    10.1016/j.carbpol.2009.10.050
  107. Fernandes, J.C.; Tavaria, F.K.; Fonseca, S.C.; Ramos, Ó.S.; Pintado, M.E.; Malcata, F.X.. "In vitro screening for antimicrobial activity of chitosans and chitooligosaccharides, aiming at potential uses in functional textiles". Journal of Microbiology and Biotechnology 20 2 (2010): 311-318. http://www.scopus.com/inward/record.url?eid=2-s2.0-77649220273&partnerID=MN8TOARS.
    10.4014/jmb.0904.04038
  108. Fernandes, J.C.; Eaton, P.; Gomes, A.M.; Pintado, M.E.; Xavier Malcata, F.. "Study of the antibacterial effects of chitosans on Bacillus cereus (and its spores) by atomic force microscopy imaging and nanoindentation". Ultramicroscopy 109 8 (2009): 854-860. http://www.scopus.com/inward/record.url?eid=2-s2.0-67449168143&partnerID=MN8TOARS.
    10.1016/j.ultramic.2009.03.015
  109. Paiva-Martins, F.; Fernandes, J.; Rocha, S.; Nascimento, H.; Vitorino, R.; Amado, F.; Borges, F.; Belo, L.; Santos-Silva, A.. "Effects of olive oil polyphenols on erythrocyte oxidative damage". Molecular Nutrition and Food Research 53 5 (2009): 609-616. http://www.scopus.com/inward/record.url?eid=2-s2.0-67649126555&partnerID=MN8TOARS.
    10.1002/mnfr.200800276
  110. Fernandes, J.C.; Eaton, P.; Nascimento, H.; Belo, L.; Rocha, S.; Vitorino, R.; Amado, F.; et al. "Effects of chitooligosaccharides on human red blood cell morphology and membrane protein structure". Biomacromolecules 9 12 (2008): 3346-3352. http://www.scopus.com/inward/record.url?eid=2-s2.0-58149147331&partnerID=MN8TOARS.
    10.1021/bm800622f
  111. Fernandes, J.C.; Tavaria, F.K.; Soares, J.C.; Ramos, O.S.; João Monteiro, M.; Pintado, M.E.; Xavier Malcata, F.. "Antimicrobial effects of chitosans and chitooligosaccharides, upon Staphylococcus aureus and Escherichia coli, in food model systems". Food Microbiology 25 7 (2008): 922-928. http://www.scopus.com/inward/record.url?eid=2-s2.0-49449107853&partnerID=MN8TOARS.
    10.1016/j.fm.2008.05.003
  112. Eaton, P.; Fernandes, J.C.; Pereira, E.; Pintado, M.E.; Xavier Malcata, F.. "Atomic force microscopy study of the antibacterial effects of chitosans on Escherichia coli and Staphylococcus aureus". Ultramicroscopy 108 10 (2008): 1128-1134. http://www.scopus.com/inward/record.url?eid=2-s2.0-49949093141&partnerID=MN8TOARS.
    10.1016/j.ultramic.2008.04.015
  113. Fernandes, J.; Gomes, F.; Couto, J.A.; Hogg, T.. "The antimicrobial effect of wine on Listeria innocua in a model stomach system". Food Control 18 12 (2007): 1477-1483. http://www.scopus.com/inward/record.url?eid=2-s2.0-34347346080&partnerID=MN8TOARS.
    10.1016/j.foodcont.2006.11.003
Capítulo de livro
  1. David M. Pereira; Fernandes JC. "The power of genomics, metabolomics, and other omics for target identification and validation". editado por Martin Wehling, 33-48. Elsevier, 2021.
    10.1016/B978-0-12-820493-1.00025-8
  2. Fernandes, João. ""Omics” Technologies: Promises and Benefits for Molecular Medicine". In Principles of Translational Science in Medicine: From Bench to Bedside, 25-37. 2015.
  3. Fernandes, João. "Modulation of Erythropoietin Gene Expression". In Frontiers in Drug Discovery: Erythropoietic Stimulating Agents, 27-42. BENTHAM SCIENCE PUBLISHERS, 2013.
    Publicado • 10.2174/9781608057474113010005
  4. Fernandes, João. "Application of Antioxidant Plants as Anti-Hemolytic Agents". In Medicinal Plants: Antioxidant Properties, Traditional Uses and Conservation Strategies, 165-182. Nova Publishers, 2013.
    Publicado
Livro
  1. Tavaria, F.K.; Fernandes, J.; Santos-Silva, A.; Silva, S.B.; Sarmento, B.; Pintado, M.. Biological activities of chitin, chitosan and respective oligomers. 2011.
  2. Silva, S.B.; Fernandes, J.; Tavaria, F.K.; Pintado, M.; Sarmento, B.. The potential of chitosan in drug delivery systems. 2011.
Poster em conferência
  1. Casanova, Francisca; Carla F. Pereira; Alessandra Braga Ribeiro; R. Freixo; Eduardo Costa; Pintado, M.; Fernandes JC; Oscar L Ramos. "Design of cellulose based micro and nanostructures for encapsulation and release of curcumin". 2022.
  2. Pedro Sousa; Helena R. Moreira; António Conde; Azevedo-Silva, J.; Manuela Amorim; Diana Tavares-Valente; Pintado, M.; Fernandes JC. "Glucans". 2022.
  3. Casanova, Francisca; Carla F. Pereira; R. Freixo; Alessandra Braga Ribeiro; Eduardo Costa; Pintado, M.; Fernandes JC; Oscar L Ramos. "Design of green routes for cellulose extraction from a sugarcane by-product". 2021.
  4. Casanova, Francisca; Carla F. Pereira; R. Freixo; Eduardo Costa; Alessandra Braga Ribeiro; Pintado, M.; Fernandes JC; Oscar L Ramos. "Sugarcane as a sustainable source of biologically active carboxymethyl cellulose". 2021.
  5. Débora Campos; Alexandra C. Ribeiro; Eduardo Costa; Fernandes JC; Freni Kekhasharú Tavaria; Peter Eaton; José Roberto S.A. Leite; Pintado, M.. "Evaluation of antimicrobial activity and atomic force microscopy imaging of the action mechanism of Cashew Tree Gum". 2011.
Resumo em conferência
  1. Ribeiro, Sandra; Nunes, Sara; Garripo, Patricia; Fernandes, João; Rocha, S; Reis, Flávio; Santos-Silva, Alice. "Liver iron regulates hepcidin expression. Studies in a rat model of chronic renal failure under recombinant human erythropoietin therapy". Trabalho apresentado em 40th Congress of the Federation-Of-EuropeanBiochemical-Societies (Febs), 2015.
    Publicado
  2. Sereno, José Vitor Oliveira; Rodrigues-Santos, Paulo; Vala, Helena; Rocha-Pereira, Petronila; Fernandes, João; Santos-Silva, Alice; Teixeira, Frederico; Reis, Flávio. "Biomarkers of transition from Cyclosporine-induced renal dysfunction to nephrotoxicity". Trabalho apresentado em 51th Congress of ERA-EDTA (European Renal Association - European Dialysis and Transplant Association), Amsterdam, 2014.
    Publicado

Outros

Outra produção
  1. Anti-inflammatory effect of chitosan oligomers. 2009. H. Spindola; Fernandes JC; V. De Sousa; Freni Kekhasharú Tavaria; Pintado, M.; Francisco Malcata; J. E. Carvalho. https://ciencia.ucp.pt/en/publications/76ffb1af-6e08-4315-8eae-9ed89e327655.
    10.1016/j.nbt.2009.06.025
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2019/07 ALCHEMY Project: Capturing High Value from Industrial Fermentation BioProduts. Ciência 2019
(Lisboa, Portugal)
2019/04 Alchemy: da investigação à inovação. 8º Ciclo de Tertúlias na Biotecnologia
(Porto, Portugal)
2018/11 Projeto Alchemy. XXI Jornadas de Engenharia Biológica
(Braga, Portugal)
2018/07 Amyris Value IV Jornadas Universidade - Empresa na Formação Pós-Graduada
(Porto, Portugal)
2016/02 Liver iron is a major regulator of hepcidin gene expression via BMP/SMAD pathway in a rat model of chronic renal failure under treatment with high rHuEPO doses. XLVI Reunião Anual da Sociedade Portuguesa de Farmacologia,
(Porto, Portugal)
2016/02 A new small-molecule activator of wild-type and mutant p53 with potential antitumor properties. XXXII Reunião de Farmacologia Clínica
2012/02 Chitooligosaccharides - bioactive properties with pharmacological potential. XXX Reunião de Farmacologia Clínica
2012 Erythropoietic response to rhEPO therapy is dependent on the stage of renal failure - an experimental study in nephrectomized rats. XXVI Congresso Português de Nefrologia,
(Faro, Portugal)
2012 Marcadores de doença cardiovascular e sua associação com alterações na membrana eritrocitária em uma população pediátrica obesa Hemorreologia, Hemóstase e Inflamação na Patologia Vascular – da investigação à Prática Clínica
(Lisboa, Portugal)
2012 Lifestyle intervention in obese children and adolescent impact on cardiovascular risk factors V Clinical Biochemistry Workshop
(Coimbra, Portugal)
2012 From conventional hemodialysis to online hemodiafiltration: impact on cardiovascular risk factors XX Congresso Nacional de Aterosclerose
(Coimbra, Portugal)
2011 Quitosanos – propriedades biológicas e possíveis aplicações em biomedicina I Seminário Internacional de Investigação em Saúde
(Porto, Portugal)
2011 Influence of genetic and non-genetic factor in PON1 activity XIX congresso Nacional de Aterosclerose
(Évora, Portugal)
2010/11 Chitosan oligomers: considerations on their therapeutical applications Biotecnologia, II Semana dos cursos do Instituto Politécnico de Coimbra
(coimbra, Portugal)
2010/07 Chitosan oligomers: considerations on their therapeutical applications ICPAC 2010 – International Conference on Pure and Applied Chemistry
(Mauritânia)
2010 Effect of Films Manufactured using Whey Protein Isolate and Concentrate at Different Contents of Glycerol MATBIM 2010, First International Meeting on Material/Bioproduct Interactions
(Paris, França)
2009/10 Actividade biológica de oligoquitosanos Quimera – Jornadas de Biotecnologia 2009
(Porto, Portugal)
2009/07 Bioactive properties of chitooligosaccharides EUROCARB 2009
(Viena)
2009/06 Biological properties and potential applications of chitosan oligomers Polymers in Medicine and Biology
(Santa Rosa, Estados Unidos)
2009/05 Evaluation of the cytotoxicity and genotoxicity of chitooligosaccharides upon human lymphocytes International Conference of the European Chitin Society
(Veneza)
2009/05 Antioxidant activity of chitooligosaccharides upon two biological systems: Erythrocytes and Bacteriophages 9th International Conference of the European Chitin Society
(Veneza)
2008/06 Study of antibacterial effects of chitosans upon vegetative and spore forms of Bacillus by atomic force microscopy imaging and nanoindentation International Scanning Probe Microscopy Conference
(Seattle, Estados Unidos)
2007 Evaluation of the prebiotic potential of chitooligosaccharides, EUCHIS’07 – 8th International Conference of the European Chitin Society
(Antalya, Turquia)
2006/08 Effect of Chitosans and Chitoligosaccharides upon Growth of Microorganisms Contaminating 93rd Annual Meeting International Association for Food Protection
(Calgary, Estados Unidos)

Orientação

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2019/09/01 - Atual Valorization of ß-glucans extracts into high-value skincare ingredients
Orientador
 Doutoramento em Biotecnologia (Doutoramento)
Portuguesa Centro de Biotecnologia e Química Fina, Portugal
2019/07/01 - 2024/01/26 Is Cannabidiol the skincare industry's next cosmeceutical?
Orientador de Mariana Veiga
 Doutoramento em Biotecnologia (Doutoramento)
Portuguesa Centro de Biotecnologia e Química Fina, Portugal
2019/09/01 - 2023/12/14 Design of micro- and nanostructures from sugarcane industry by-products for encapsulation and controlled release of active biomolecules
Coorientador
 Doutoramento em Biotecnologia (Doutoramento)
Portuguesa Centro de Biotecnologia e Química Fina, Portugal
2018/09/01 - 2019/06/30 Market Potential Analysis of a Beta-glucans as antibiotic replacer in animal feed
Orientador
 Joint European Master of Science in Food Science, Technology, and Business (BiFTec) (Mestrado)
Portuguesa Centro de Biotecnologia e Química Fina, Portugal
2012/09/04 - 2013/06/03 Efeitos de metabolitos de fenóis do azeite no dano oxidativo em eritrócitos humanos
Coorientador
 Mestrado em Bioquímica
Universidade do Porto Faculdade de Ciências, Portugal

Júri de grau académico

Tema
Tipo de participação 		Nome do candidato (Tipo de grau)
Instituição / Organização
2024/04/09 Anti-inflammatory properties of plant species from Guinea-Bissau: A contribute to ethnopharmacology
Arguente principal
 Tiago Manuel Gonçalves Macedo (Doutoramento)
2023/07/23 The natural product chemical space for modulating endoplasmic reticulum stress in chronic diseases
Arguente principal
 Daniela Correia da Silva (Doutoramento)
Universidade do Porto Faculdade de Farmácia, Portugal

Membro de associação

Nome da associação Tipo de participação
2016 - Atual Royal Society of Biology Full Member
Distinções

Outra distinção

2017 8 hot papers and 11 highly cited papers in different fields (Clinical Medicine, Immunology and Food Sciences)
2014 One of Best Abstracts presented by young authors (1st author of the work)
2012 Roche Prize for best presentation in Basic Nephrology area in the XXVI Nephrology Portuguese Congress
2012 One of Best Abstracts presented by young authors (co-author of the work)
2011 Start-Now Prize for best Start-Now company among 3000 competitors
2011 UPk25 Public Award
2010 Best Poster in the congress "Obesity - a multidisciplinary vision"