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Anabela Rolo, Ph.D. is an Associate Professor in the Department of Life Sciences, University of Coimbra, Portugal and Investigator at the Center for Neurosciences and Cell Biology from the same University. Her research interests are focused on the pathophysiological mechanisms of mitochondrial dysfunction and human health, particularly on the signaling pathways that regulate mitochondrial turnover expertise in metabolic diseases. Anabela Rolo has published over 97 papers with an h factor of 33 and 62,67 citations per paper on average. She is currently on the Editorial Board for the journals Toxicology and Applied Pharmacology and Toxicology Mechanisms and Methods. Anabela Rolo is supervisor of one ongoing PhD, has co-supervised 5 PhD theses, supervised 5 MSc dissertations and co-supervised 13. Participates and/or participated as researcher in 12 projects. She was trained as a Biologist at the University of Coimbra, Portugal from where she also received her Ph.D. and postdoctoral training in Biochemical Toxicology at the University of Minnesota, Duluth, USA and Cellular Biology at the University of California, Davis, USA.
Identificação

Identificação pessoal

Nome completo
Anabela Pinto Rolo

Nomes de citação

  • Rolo AP
  • Rolo A

Identificadores de autor

Ciência ID
8710-919C-E2A5
ORCID iD
0000-0003-3535-9630

Endereços de correio eletrónico

  • anpiro@ci.uc.pt (Profissional)

Domínios de atuação

  • Ciências Naturais - Ciências Biológicas - Biologia Celular
Formação
Grau Classificação
2003
Concluído
Doutoramento em Biologia Celular (Doutoramento)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Cholestasis and hepatic ischemia: bile acids therapy. Cellular mechanisms with relevance to mitochondrial function." (TESE/DISSERTAÇÃO)
Unanimidade com louvor e distinção
1999/07/31
Concluído
Licenciatura em Biologia (Licenciatura)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"na" (TESE/DISSERTAÇÃO)
18 valores
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento
Empregador
2009 - 2013 Investigador Auxiliar (carreira) (Investigação) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2006 - 2009 Pós-doutorado (Investigação) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2003 - 2006 Pós-doutorado (Investigação) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento
Empregador
2015 - 2022/12/31 Professor Auxiliar (Docente Universitário) Universidade de Coimbra, Portugal
2013 - 2015 Professor Auxiliar (Docente Universitário) Universidade de Aveiro, Portugal
Universidade de Aveiro Departamento de Biologia, Portugal
2007 - 2013 Professor Auxiliar Convidado (Docente Universitário) Universidade de Aveiro, Portugal
Universidade de Aveiro Departamento de Biologia, Portugal
1998 - 1999 Assistente (Docente Universitário) Universidade de Coimbra, Portugal
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
Projetos

Projeto

Designação Financiadores
2018 - Atual FRUITIFY - Use of blueberry juice as a nutraceutical strategy targeting gut dysbiosis to prevent the progression from prediabetes to diabetes
PTDC/SAU-NUT/31712/2017
Investigador
Instituto Biomédico de Investigação da Luz e da Imagem, Portugal
Concluído
2016 - 2019 EXERCISING THE FUTURE: VOLUNTARY EXERCISE DURING GESTATIONAL DIABETES AS A MEANS TO IMPROVE MITOCHONDRIAL FUNCTION IN THE OFFSPRING
PTDC/DTP-DES/1082/2014
Investigador
Fundação para a Ciência e a Tecnologia
Concluído
2016 - 2019 THE INTERPLAY BETWEEN CAMP AND SIRTUINS AS A NEXUS OF MITOCHONDRIAL AND METABOLIC CONTROL
PTDC/BIM-MEC/6911/2014
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2013 - 2014 Chronic effects of silver nanoparticles (AgNPs) on rat liver, kidney and heart mitochondrial function
NA
Investigador
Concluído
2010 - 2013 LONG-TERM BENEFICIAL INFLUENCE OF EARLY METABOLIC CONTROL: PREVENTION OF HYPERGLYCEMIC MEMORY TROUGH STIMULATION OF BIOENERGETICS
PTDC/QUIBIQ/ 103514/2008
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2010 - 2013 Mechanisms underlying the effects of nitric oxide on neural stem cell proliferation in brain injury
PTDC/SAU-NEU/102612/2008
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2011 - 2012 ABILITY OF A MITOCHONDRIAL IMPROVER, BERBERINE, TO ATTENUATE PARKINSON ´S DISEASE
NA
Investigador
Concluído
2008 - 2010 MODULATION OF METABOLIC PATHWAYS INVOLVED IN MITOCHONDRIAL OXIDATIVE STRESS CAUSED BY HYPERGLYCEMIC CONDITIONS:RELEVANCE FOR DIABETES PREVENTION
PTDC/QUIM/72826/2006
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2007 - 2010 DISTURBANCE OF THE PHYSIOLOGIC PATHWAYS AND MOLECULAR MECHANISMS REGULATING ENERGY HOMEOSTASIS IN OBESITY AND METABOLIC SYNDROME: SEARCHING NEW STRATEGIES AND THERAPEUTIC TARGETS
PTDC/SAU-OSM/72443/2006
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2007 - 2008 IN VITRO ASSESSMENT OF SILVER NANOPARTICLES TOXICITY IN HEPATIC MITOCHONDRIAL FUNCTION
FA8655-07- 1-3047
Investigador
Concluído
2007 - 2007 13C NMR ISOTOPOMER ANALYSIS OF INTERMEDIARY METABOLISM IN A ADRIAMYCIN HEART FAILURE MODEL
1774-602-6050-7901
Investigador
National Heart Lung and Blood Institute
Concluído
2002 - 2005 COLESTASE E ESTEATOSE HEPÁTICA: TERAPIA COM ÁCIDOS BILIARES. MECANISMOS CELULARES COM RELEVÂNCIA NA FUNÇÃO MITOCONDRIAL
POCTI/CBO/42486/2001
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
Produções

Publicações

Artigo em revista
  1. Machado, Ivo F.; Miranda, Raul G.; Dorta, Daniel J.; Rolo, Anabela P.; Palmeira, Carlos M.. "Targeting Oxidative Stress with Polyphenols to Fight Liver Diseases". Antioxidants 12 6 (2023): 1212. http://dx.doi.org/10.3390/antiox12061212.
    10.3390/antiox12061212
  2. Lopes, Cátia R.; Silva, Joana S.; Santos, Joana; Rodrigues, Matilde S.; Madeira, Daniela; Oliveira, Andreia; Moreira-de-Sá, Ana; et al. "Downregulation of Sirtuin 1 Does Not Account for the Impaired Long-Term Potentiation in the Prefrontal Cortex of Female APPswe/PS1dE9 Mice Modelling Alzheimer’s Disease". International Journal of Molecular Sciences 24 8 (2023): 6968. http://dx.doi.org/10.3390/ijms24086968.
    10.3390/ijms24086968
  3. Machado, Ivo F.; Palmeira, Carlos M.; Rolo, Anabela P.. "Preservation of Mitochondrial Health in Liver Ischemia/Reperfusion Injury". Biomedicines 11 3 (2023): 948. http://dx.doi.org/10.3390/biomedicines11030948.
    10.3390/biomedicines11030948
  4. Teodoro, João S.; Da Silva, Rui T.; Machado, Ivo F.; Panisello-Roselló, Arnau; Roselló-Catafau, Joan; Rolo, Anabela P.; Palmeira, Carlos M.. "Shaping of Hepatic Ischemia/Reperfusion Events: The Crucial Role of Mitochondria". Cells 11 4 (2022): 688. http://dx.doi.org/10.3390/cells11040688.
    10.3390/cells11040688
  5. Amorim, João A.; Coppotelli, Giuseppe; Rolo, Anabela P.; Palmeira, Carlos M.; Ross, Jaime M.; Sinclair, David A.. "Mitochondrial and metabolic dysfunction in ageing and age-related diseases". Nature Reviews Endocrinology (2022): http://dx.doi.org/10.1038/s41574-021-00626-7.
    10.1038/s41574-021-00626-7
  6. Teixeira da Silva, Rui; Machado, Ivo F.; Teodoro, João S.; Panisello-Roselló, Arnau; Roselló-Catafau, Joan; Rolo, Anabela P.; Palmeira, Carlos M.. "PEG35 as a Preconditioning Agent against Hypoxia/Reoxygenation Injury". International Journal of Molecular Sciences 23 3 (2022): 1156. http://dx.doi.org/10.3390/ijms23031156.
    10.3390/ijms23031156
  7. Nunes, Sara; Viana, Sofia D.; Preguiça, Inês; Alves, André; Fernandes, Rosa; Teodoro, João S.; Matos, Patrícia; et al. "Blueberry Counteracts Prediabetes in a Hypercaloric Diet-Induced Rat Model and Rescues Hepatic Mitochondrial Bioenergetics". Nutrients 13 12 (2021): 4192. http://dx.doi.org/10.3390/nu13124192.
    10.3390/nu13124192
  8. Teodoro, João S.; Machado, Ivo F.; Castela, Ana C.; Amorim, João A.; Jarak, Ivana; Carvalho, Rui A.; Palmeira, Carlos M.; Rolo, Anabela P.. "Chenodeoxycholic Acid Has Non-Thermogenic, Mitodynamic Anti-Obesity Effects in an In Vitro CRISPR/Cas9 Model of Bile Acid Receptor TGR5 Knockdown". International Journal of Molecular Sciences 22 21 (2021): 11738. http://dx.doi.org/10.3390/ijms222111738.
    10.3390/ijms222111738
  9. Piochi, Luiz F.; Machado, Ivo F.; Palmeira, Carlos M.; Rolo, Anabela P.. "Sestrin2 and mitochondrial quality control: Potential impact in myogenic differentiation". Ageing Research Reviews 67 (2021): 101309. http://dx.doi.org/10.1016/j.arr.2021.101309.
    Publicado • 10.1016/j.arr.2021.101309
  10. Oliveira, Raúl P.; Machado, Ivo F.; Palmeira, Carlos M.; Rolo, Anabela P.. "The potential role of sestrin 2 in liver regeneration". Free Radical Biology and Medicine 163 (2021): 255-267. http://dx.doi.org/10.1016/j.freeradbiomed.2020.12.027.
    10.1016/j.freeradbiomed.2020.12.027
  11. Machado, Ivo F.; Teodoro, João S.; Castela, Ana C.; Palmeira, Carlos M.; Rolo, Anabela P.. "miR-378a-3p Participates in Metformin’s Mechanism of Action on C2C12 Cells under Hyperglycemia". International Journal of Molecular Sciences 22 2 (2021): 541. http://dx.doi.org/10.3390/ijms22020541.
    10.3390/ijms22020541
  12. Nunes, Sara; Viana, Sofia D.; Preguiça, Inês; Alves, André; Fernandes, Rosa; Teodoro, João S.; Figueirinha, Artur; et al. "Blueberry Consumption Challenges Hepatic Mitochondrial Bioenergetics and Elicits Transcriptomics Reprogramming in Healthy Wistar Rats". Pharmaceutics 12 11 (2020): 1094. http://dx.doi.org/10.3390/pharmaceutics12111094.
    10.3390/pharmaceutics12111094
  13. Teodoro, João S.; Amorim, João A.; Machado, Ivo F.; Castela, Ana C.; Steegborn, Clemens; Sinclair, David A.; Rolo, Anabela P.; Palmeira, Carlos M.. "The Soluble Adenylyl Cyclase Inhibitor LRE1 Prevents Hepatic Ischemia/Reperfusion Damage Through Improvement of Mitochondrial Function". International Journal of Molecular Sciences 21 14 (2020): 4896. http://dx.doi.org/10.3390/ijms21144896.
    10.3390/ijms21144896
  14. Teodoro, João S.; Silva, Rui; Aguiar, António; Sobral, Abílio J. F. N.; Rolo, Anabela P.; Palmeira, Carlos M.. "Exploration of the cellular effects of the high-dose, long-term exposure to coffee roasting product furan and its by-product cis-2-butene-1,4-dial on human and rat hepatocytes". Toxicology Mechanisms and Methods 30 7 (2020): 536-545. http://dx.doi.org/10.1080/15376516.2020.1780361.
    10.1080/15376516.2020.1780361
  15. Makrecka-Kuka, Marina; Liepinsh, Edgars; Murray, Andrew J.; Lemieux, Hélène; Dambrova, Maija; Tepp, Kersti; Puurand, Marju; et al. "Altered mitochondrial metabolism in the insulin-resistant heart". Acta Physiologica 228 3 (2020): http://dx.doi.org/10.1111/apha.13430.
    10.1111/apha.13430
  16. Gomes P; Viana SD; Nunes S; Rolo AP; Palmeira CM; Reis F. "The yin and yang faces of the mitochondrial deacetylase sirtuin 3 in age-related disorders.". Ageing research reviews (2020): http://europepmc.org/abstract/med/31740222.
    10.1016/j.arr.2019.100983
  17. Milton-Laskibar, I.; Aguirre, L.; Gómez-Zorita, S.; Rolo, A. P.; Portillo, M. P.. "The influence of dietary conditions in the effects of resveratrol on hepatic steatosis". Food & Function 11 11 (2020): 9432-9444. http://dx.doi.org/10.1039/d0fo01943g.
    10.1039/d0fo01943g
  18. Machado, Ivo F.; Teodoro, João S.; Palmeira, Carlos M.; Rolo, Anabela P.; Machado IF; Teodoro JS; Palmeira CM; Rolo AP. "miR-378a: a new emerging microRNA in metabolism". Cellular and molecular life sciences : CMLS (2020): http://europepmc.org/abstract/med/31748917.
    Publicado • 10.1007/s00018-019-03375-z
  19. Martins RM; Teodoro JS; Furtado E; Oliveira RC; Tralhão JG; Rolo AP; Palmeira CM. "Mild hypothermia during the reperfusion phase protects mitochondrial bioenergetics against ischemia-reperfusion injury in an animal model of ex-vivo liver transplantation-an experimental study.". International journal of medical sciences (2019): http://europepmc.org/abstract/med/31588197.
    10.7150/ijms.34617
  20. Palmeira CM; Teodoro JS; Amorim JA; Steegborn C; Sinclair DA; Rolo AP. "Mitohormesis and metabolic health: The interplay between ROS, cAMP and sirtuins.". Free radical biology & medicine (2019): http://europepmc.org/abstract/med/31349039.
    10.1016/j.freeradbiomed.2019.07.017
  21. Martins RM; Teodoro JS; Furtado E; Rolo AP; Palmeira CM; Tralhão JG. "Evaluation of bioenergetic and mitochondrial function in liver transplantation.". Clinical and molecular hepatology (2019): http://europepmc.org/abstract/med/30897898.
    10.3350/cmh.2018.0087
  22. Panisello-Roselló A; Alva N; Flores M; Lopez A; Castro Benítez C; Folch-Puy E; Rolo A; et al. "Aldehyde Dehydrogenase 2 (ALDH2) in Rat Fatty Liver Cold Ischemia Injury.". International Journal of Molecular Sciences (2018): http://europepmc.org/abstract/med/30131474.
    10.3390/ijms19092479
  23. Panisello-Roselló A; Lopez A; Folch-Puy E; Carbonell T; Rolo A; Palmeira C; Adam R; Net M; Roselló-Catafau J. "Role of aldehyde dehydrogenase 2 in ischemia reperfusion injury: An update.". World journal of gastroenterology (2018): http://europepmc.org/abstract/med/30038465.
    10.3748/wjg.v24.i27.2984
  24. Pereira LC; Cabral Miranda LF; Franco-Bernardes MF; Tasso MJ; Duarte FV; Inácio Varela AT; Rolo AP; Marques Palmeira CM; Dorta DJ. "Mitochondrial damage and apoptosis: Key features in BDE-153-induced hepatotoxicity.". Chemico-biological interactions (2018): http://europepmc.org/abstract/med/29935161.
    10.1016/j.cbi.2018.06.021
  25. Teodoro JS; Varela AT; Duarte FV; Gomes AP; Palmeira CM; Rolo AP. "Indirubin and NAD+ prevent mitochondrial ischaemia/reperfusion damage in fatty livers.". European journal of clinical investigation (2018): http://europepmc.org/abstract/med/29603199.
    10.1111/eci.12932
  26. Martins RM; Teodoro JS; Furtado E; Rolo AP; Palmeira CM; Tralhão JG. "Recent insights into mitochondrial targeting strategies in liver transplantation.". International journal of medical sciences (2018): http://europepmc.org/abstract/med/29483816.
    10.7150/ijms.22891
  27. Teodoro JS; Nunes S; Rolo AP; Reis F; Palmeira CM. "Therapeutic Options Targeting Oxidative Stress, Mitochondrial Dysfunction and Inflammation to Hinder the Progression of Vascular Complications of Diabetes.". Frontiers in physiology (2018): http://europepmc.org/abstract/med/30705633.
    10.3389/fphys.2018.01857
  28. Egea, J.; Fabregat, I.; Frapart, Y.M.; Ghezzi, P.; Görlach, A.; Kietzmann, T.; Kubaichuk, K.; et al. "Corrigendum to “European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)”". Redox Biology 14 (2018): 694-696. http://www.scopus.com/inward/record.url?eid=2-s2.0-85032289195&partnerID=MN8TOARS.
    10.1016/j.redox.2017.10.001
  29. Martins, R.M.; Rolo, A.P.; Teodoro, J.S.; Furtado, E.; Oliveira, R.C.; Tralhão, J.G.; Palmeira, C.M.. "Addition of berberine to preservation solution in an animal model of ex vivo liver transplant preserves mitochondrial function and bioenergetics from the damage induced by ischemia/reperfusion". International Journal of Molecular Sciences 19 1 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85040938454&partnerID=MN8TOARS.
    10.3390/ijms19010284
  30. Panisello-Roselló, A.; Verde, E.; Lopez, A.; Flores, M.; Folch-Puy, E.; Rolo, A.; Palmeira, C.; et al. "Cytoprotective mechanisms in fatty liver preservation against cold ischemia injury: A comparison between IGL-1 and HTK". International Journal of Molecular Sciences 19 2 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85041019515&partnerID=MN8TOARS.
    10.3390/ijms19020348
  31. Alexandrino H; Rolo A; Teodoro JS; Donato H; Martins R; Serôdio M; Martins M; et al. "Bioenergetic adaptations of the human liver in the ALPPS procedure - how liver regeneration correlates with mitochondrial energy status.". HPB : The Official Journal of the International Hepato Pancreato Biliary Association (2017): http://europepmc.org/abstract/med/28941575.
    10.1016/j.hpb.2017.08.005
  32. Egea, Javier; Fabregat, Isabel; Frapart, Yves M.; Ghezzi, Pietro; Görlach, Agnes; Kietzmann, Thomas; Kubaichuk, Kateryna; et al. "European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)". Redox Biology 13 (2017): 94-162. http://dx.doi.org/10.1016/j.redox.2017.05.007.
    10.1016/j.redox.2017.05.007
  33. Milton-Laskibar I; Aguirre L; Fernández-Quintela A; Rolo AP; Soeiro Teodoro J; Palmeira CM; Portillo MP. "Lack of Additive Effects of Resveratrol and Energy Restriction in the Treatment of Hepatic Steatosis in Rats.". Nutrients (2017): http://europepmc.org/abstract/med/28696376.
    10.3390/nu9070737
  34. Duarte FV; Amorim JA; Varela AT; Teodoro JS; Gomes AP; Cunha RA; Palmeira CM; Rolo AP. "Adenosine receptors: regulatory players in the preservation of mitochondrial function induced by ischemic preconditioning of rat liver.". (2017): http://europepmc.org/abstract/med/27848069.
    10.1007/s11302-016-9548-x
  35. Pereira LC; Duarte FV; Varela ATIF; Rolo AP; Palmeira CMM; Dorta DJ. "Exposure to BDE-153 induces autophagy in HepG2 cells.". (2017): http://europepmc.org/abstract/med/28396260.
    10.1016/j.tiv.2017.04.005
  36. Zaouali MA; Panisello A; Lopez A; Castro C; Folch E; Carbonell T; Rolo A; et al. "GSK3ß and VDAC Involvement in ER Stress and Apoptosis Modulation during Orthotopic Liver Transplantation.". (2017): http://europepmc.org/abstract/med/28282906.
    10.3390/ijms18030591
  37. Pereira LC; Duarte FV; Varela AT; Rolo AP; Palmeira CM; Dorta DJ. "An autophagic process is activated in HepG2 cells to mediate BDE-100-induced toxicity.". (2017): http://europepmc.org/abstract/med/27234317.
    10.1016/j.tox.2016.05.022
  38. Amorim, J.A.; Canas, P.M.; Tomé, A.R.; Rolo, A.P.; Agostinho, P.; Palmeira, C.M.; Cunha, R.A.; et al. "Mitochondria in Excitatory and Inhibitory Synapses have Similar Susceptibility to Amyloid-ß Peptides Modeling Alzheimer's Disease". Journal of Alzheimer's Disease 60 2 (2017): 525-536. http://www.scopus.com/inward/record.url?eid=2-s2.0-85029613373&partnerID=MN8TOARS.
    10.3233/JAD-170356
  39. Rossetti A; Togliatto G; Rolo AP; Teodoro JS; Granata R; Ghigo E; Columbano A; Palmeira CM; Brizzi MF. "Unacylated ghrelin prevents mitochondrial dysfunction in a model of ischemia/reperfusion liver injury.". Cell death discovery (2017): http://europepmc.org/abstract/med/29354291.
    10.1038/cddiscovery.2017.77
  40. Teodoro JS; Gomes AP; Varela AT; Duarte FV; Rolo AP; Palmeira CM. "Hepatic and skeletal muscle mitochondrial toxicity of chitosan oligosaccharides of normal and diabetic rats.". (2016): http://europepmc.org/abstract/med/27790925.
    10.1080/15376516.2016.1222643
  41. Teodoro JS; Rolo AP; Jarak I; Palmeira CM; Carvalho RA. "The bile acid chenodeoxycholic acid directly modulates metabolic pathways in white adipose tissue in vitro: insight into how bile acids decrease obesity.". (2016): http://europepmc.org/abstract/med/27488269.
    10.1002/nbm.3583
  42. Alexandrino H; Varela AT; Teodoro JS; Martins MA; Rolo AP; Tralhão JG; Palmeira CM; Castro E Sousa F. "Mitochondrial bioenergetics and posthepatectomy liver dysfunction.". (2016): http://europepmc.org/abstract/med/27138992.
    10.1111/eci.12639
  43. Teodoro JS; Silva R; Varela AT; Duarte FV; Rolo AP; Hussain S; Palmeira CM. "Low-dose, subchronic exposure to silver nanoparticles causes mitochondrial alterations in Sprague-Dawley rats.". (2016): http://europepmc.org/abstract/med/27171910.
    10.2217/nnm-2016-0049
  44. Görlach A; Dimova EY; Petry A; Martínez-Ruiz A; Hernansanz-Agustín P; Rolo AP; Palmeira CM; Kietzmann T. "Reactive oxygen species, nutrition, hypoxia and diseases: Problems solved?". (2015): http://europepmc.org/abstract/med/26339717.
    10.1016/j.redox.2015.08.016
  45. Pantazi E; Zaouali MA; Bejaoui M; Folch-Puy E; Ben Abdennebi H; Varela AT; Rolo AP; Palmeira CM; Roselló-Catafau J. "Sirtuin 1 in rat orthotopic liver transplantation: an IGL-1 preservation solution approach.". (2015): http://europepmc.org/abstract/med/25684941.
    10.3748/wjg.v21.i6.1765
  46. Pantazi, E.; Bejaoui, M.; Zaouali, M.A.; Folch-Puy, E.; Rolo, A.P.; Panisello, A.; Palmeira, C.M.; Roselló-Catafau, J.. "Losartan activates sirtuin 1 in rat reduced-size orthotopic liver transplantation". World Journal of Gastroenterology 21 26 (2015): 8021-8031. http://www.scopus.com/inward/record.url?eid=2-s2.0-84937022268&partnerID=MN8TOARS.
    10.3748/wjg.v21.i26.8021
  47. Duarte FV; Amorim JA; Palmeira CM; Rolo AP. "Regulation of Mitochondrial Function and its Impact in Metabolic Stress.". (2015): http://europepmc.org/abstract/med/25973983.
    10.2174/0929867322666150514095910
  48. Pantazi E; Folch-Puy E; Bejaoui M; Panisello A; Varela AT; Rolo AP; Palmeira CM; Roselló-Catafau J. "PPARa Agonist WY-14643 Induces SIRT1 Activity in Rat Fatty Liver Ischemia-Reperfusion Injury.". (2015): http://europepmc.org/abstract/med/26539534.
    10.1155/2015/894679
  49. Teodoro JS; Zouhar P; Flachs P; Bardova K; Janovska P; Gomes AP; Duarte FV; et al. "Enhancement of brown fat thermogenesis using chenodeoxycholic acid in mice.". (2014): http://europepmc.org/abstract/med/24310401.
    10.1038/ijo.2013.230
  50. Teodoro JS; Varela AT; Rolo AP; Palmeira CM. "High-fat and obesogenic diets: current and future strategies to fight obesity and diabetes.". (2014): http://europepmc.org/abstract/med/24842072.
    10.1007/s12263-014-0406-6
  51. Carmo MR; Menezes AP; Nunes AC; Pliássova A; Rolo AP; Palmeira CM; Cunha RA; Canas PM; Andrade GM. "The P2X7 receptor antagonist Brilliant Blue G attenuates contralateral rotations in a rat model of Parkinsonism through a combined control of synaptotoxicity, neurotoxicity and gliosis.". (2014): http://europepmc.org/abstract/med/24508709.
    10.1016/j.neuropharm.2014.01.045
  52. Duarte FV; Palmeira CM; Rolo AP. "The Role of microRNAs in Mitochondria: Small Players Acting Wide.". (2014): http://europepmc.org/abstract/med/25264560.
    10.3390/genes5040865
  53. Gomes AP; Price NL; Ling AJ; Moslehi JJ; Montgomery MK; Rajman L; White JP; et al. "Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging.". (2013): http://europepmc.org/abstract/med/24360282.
    10.1016/j.cell.2013.11.037
  54. Duarte, F.V.; Gomes, A.P.; Teodoro, J.S.; Varela, A.T.; Moreno, A.J.M.; Rolo, A.P.; Palmeira, C.M.. "Dibenzofuran-induced mitochondrial dysfunction: Interaction with ANT carrier". Toxicology in Vitro 27 8 (2013): 2160-2168. http://www.scopus.com/inward/record.url?eid=2-s2.0-84885795993&partnerID=MN8TOARS.
    10.1016/j.tiv.2013.08.009
  55. Rossato, L.G.; Costa, V.M.; Vilas-Boas, V.; De Lourdes Bastos, M.; Rolo, A.; Palmeira, C.; Remião, F.. "Therapeutic concentrations of mitoxantrone elicit energetic imbalance in H9c2 cells as an earlier event". Cardiovascular Toxicology 13 4 (2013): 413-425. http://www.scopus.com/inward/record.url?eid=2-s2.0-84890559945&partnerID=MN8TOARS.
    10.1007/s12012-013-9224-0
  56. Teodoro, J.S.; Duarte, F.V.; Gomes, A.P.; Varela, A.T.; Peixoto, F.M.; Rolo, A.P.; Palmeira, C.M.. "Berberine reverts hepatic mitochondrial dysfunction in high-fat fed rats: A possible role for SirT3 activation". Mitochondrion 13 6 (2013): 637-646. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884937949&partnerID=MN8TOARS.
    10.1016/j.mito.2013.09.002
  57. Teodoro, J.S.; Rolo, A.P.; Palmeira, C.M.. "The NAD ratio redox paradox: Why does too much reductive power cause oxidative stress?". Toxicology Mechanisms and Methods 23 5 (2013): 297-302. http://www.scopus.com/inward/record.url?eid=2-s2.0-84878533789&partnerID=MN8TOARS.
    10.3109/15376516.2012.759305
  58. Teodoro, J.S.; Gomes, A.P.; Varela, A.T.; Duarte, F.V.; Rolo, A.P.; Palmeira, C.M.. "Uncovering the beginning of diabetes: The cellular redox status and oxidative stress as starting players in hyperglycemic damage". Molecular and Cellular Biochemistry 376 1-2 (2013): 103-110. http://www.scopus.com/inward/record.url?eid=2-s2.0-84874278002&partnerID=MN8TOARS.
    10.1007/s11010-012-1555-9
  59. Hubbard, B.P.; Gomes, A.P.; Dai, H.; Li, J.; Case, A.W.; Considine, T.; Riera, T.V.; et al. "Evidence for a common mechanism of SIRT1 regulation by allosteric activators". Science 339 6124 (2013): 1216-1219. http://www.scopus.com/inward/record.url?eid=2-s2.0-84874721105&partnerID=MN8TOARS.
    10.1126/science.1231097
  60. Gomes, A.P.; Duarte, F.V.; Nunes, P.; Hubbard, B.P.; Teodoro, J.S.; Varela, A.T.; Jones, J.G.; et al. "Berberine protects against high fat diet-induced dysfunction in muscle mitochondria by inducing SIRT1-dependent mitochondrial biogenesis". Biochimica et Biophysica Acta - Molecular Basis of Disease 1822 2 (2012): 185-195. http://www.scopus.com/inward/record.url?eid=2-s2.0-83255163155&partnerID=MN8TOARS.
    10.1016/j.bbadis.2011.10.008
  61. Rolo, A.P.; Teodoro, J.S.; Palmeira, C.M.. "Role of oxidative stress in the pathogenesis of nonalcoholic steatohepatitis". Free Radical Biology and Medicine 52 1 (2012): 59-69. http://www.scopus.com/inward/record.url?eid=2-s2.0-84655169624&partnerID=MN8TOARS.
    10.1016/j.freeradbiomed.2011.10.003
  62. Palmeira, C.M.; Rolo, A.P.; Teodoro JS; Palmeira CM; Rolo AP; Teodoro, João Soeiro; Palmeira, Carlos Marques; Rolo, Anabela Pinto. "Mitochondrial membrane potential fluctuations associated with the metabolic states of mitochondria". Methods in Molecular Biology 810 (2012): 89-101. http://www.scopus.com/inward/record.url?eid=2-s2.0-82355170970&partnerID=MN8TOARS.
    10.1007/978-1-61779-382-0_6
  63. Price, N.L.; Gomes, A.P.; Ling, A.J.Y.; Duarte, F.V.; Martin-Montalvo, A.; North, B.J.; Agarwal, B.; et al. "SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function". Cell Metabolism 15 5 (2012): 675-690. http://www.scopus.com/inward/record.url?eid=2-s2.0-84860477354&partnerID=MN8TOARS.
    10.1016/j.cmet.2012.04.003
  64. Duarte, F.V.; Teodoro, J.S.; Rolo, A.P.; Palmeira, C.M.. "Exposure to dibenzofuran triggers autophagy in lung cells". Toxicology Letters 209 1 (2012): 35-42. http://www.scopus.com/inward/record.url?eid=2-s2.0-84155176935&partnerID=MN8TOARS.
    10.1016/j.toxlet.2011.11.029
  65. Teodoro, J.S.; Rolo, A.P.; Palmeira, C.M.. "Hepatic FXR: Key regulator of whole-body energy metabolism". Trends in Endocrinology and Metabolism 22 11 (2011): 458-466. http://www.scopus.com/inward/record.url?eid=2-s2.0-82455164172&partnerID=MN8TOARS.
    10.1016/j.tem.2011.07.002
  66. Varela, A.T.; Rolo, A.P.; Palmeira, C.M.. "Fatty liver and ischemia/reperfusion: Are there drugs able to mitigate injury?". Current Medicinal Chemistry 18 32 (2011): 4987-5002. http://www.scopus.com/inward/record.url?eid=2-s2.0-80054860029&partnerID=MN8TOARS.
    10.2174/092986711797535164
  67. Nunes, P.M.; Jones, J.G.; Rolo, A.P.; Palmeira, C.M.M.; Carvalho, R.A.. "Ursodeoxycholic acid treatment of hepatic steatosis: A 13C NMR metabolic study". NMR in Biomedicine 24 9 (2011): 1145-1158. http://www.scopus.com/inward/record.url?eid=2-s2.0-80054069550&partnerID=MN8TOARS.
    10.1002/nbm.1672
  68. Duarte, F.V.; Simões, A.M.; Teodoro, J.S.; Rolo, A.P.; Palmeira, C.M.. "Exposure to dibenzofuran affects lung mitochondrial function in vitro". Toxicology Mechanisms and Methods 21 8 (2011): 571-576. http://www.scopus.com/inward/record.url?eid=2-s2.0-80053260979&partnerID=MN8TOARS.
    10.3109/15376516.2011.576714
  69. Rolo, A.P.; Gomes, A.P.; Palmeira, C.M.. "Regulation of mitochondrial biogenesis in metabolic syndrome". Current Drug Targets 12 6 (2011): 872-878. http://www.scopus.com/inward/record.url?eid=2-s2.0-79955575803&partnerID=MN8TOARS.
    10.2174/138945011795529056
  70. Teodoro, J.S.; Simões, A.M.; Duarte, F.V.; Rolo, A.P.; Murdoch, R.C.; Hussain, S.M.; Palmeira, C.M.. "Assessment of the toxicity of silver nanoparticles in vitro: A mitochondrial perspective". Toxicology in Vitro 25 3 (2011): 664-670. http://www.scopus.com/inward/record.url?eid=2-s2.0-79952039156&partnerID=MN8TOARS.
    10.1016/j.tiv.2011.01.004
  71. Varela, A.T.; Simões, A.M.; Teodoro, J.S.; Duarte, F.V.; Gomes, A.P.; Palmeira, C.M.; Rolo, A.P.. "Indirubin-3'-oxime prevents hepatic I/R damage by inhibiting GSK-3ß and mitochondrial permeability transition". Mitochondrion 10 5 (2010): 456-463. http://www.scopus.com/inward/record.url?eid=2-s2.0-77955424602&partnerID=MN8TOARS.
    10.1016/j.mito.2010.04.006
  72. Simes, A.M.; Duarte, F.V.; Teodoro, J.S.; Rolo, A.P.; Palmeira, C.M.. "Exposure to 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin and tetraethyl lead affects lung mitochondria bioenergetics". Toxicology Mechanisms and Methods 20 1 (2010): 1-6. http://www.scopus.com/inward/record.url?eid=2-s2.0-77149123078&partnerID=MN8TOARS.
    10.3109/15376510903527916
  73. Rolo, A.P.; Teodoro, J.S.; Peralta, C.; Rosello-Catafau, J.; Palmeira, C.M.. "Prevention of I/R injury in fatty livers by ischemic preconditioning is associated with increased mitochondrial tolerance: The key role of ATPsynthase and mitochondrial permeability transition". Transplant International 22 11 (2009): 1081-1090. http://www.scopus.com/inward/record.url?eid=2-s2.0-70349668693&partnerID=MN8TOARS.
    10.1111/j.1432-2277.2009.00916.x
  74. Rolo, A.P.; Palmeira, C.M.; Cortopassi, G.A.. "Biosensor plates detect mitochondrial physiological regulators and mutations in vivo". Analytical Biochemistry 385 1 (2009): 176-178. http://www.scopus.com/inward/record.url?eid=2-s2.0-57749174647&partnerID=MN8TOARS.
    10.1016/j.ab.2008.10.002
  75. Varela, A.T.; Gomes, A.P.; Simões, A.M.; Teodoro, J.S.; Duarte, F.V.; Rolo, A.P.; Palmeira, C.M.. "Indirubin-3'-oxime impairs mitochondrial oxidative phosphorylation and prevents mitochondrial permeability transition induction". Toxicology and Applied Pharmacology 233 2 (2008): 179-185. http://www.scopus.com/inward/record.url?eid=2-s2.0-56049123388&partnerID=MN8TOARS.
    10.1016/j.taap.2008.08.005
  76. Teodoro, J.S.; Rolo, A.P.; Duarte, F.V.; Simões, A.M.; Palmeira, C.M.. "Differential alterations in mitochondrial function induced by a choline-deficient diet: Understanding fatty liver disease progression". Mitochondrion 8 5-6 (2008): 367-376. http://www.scopus.com/inward/record.url?eid=2-s2.0-54949089576&partnerID=MN8TOARS.
    10.1016/j.mito.2008.07.008
  77. Palmeira, C.M.; Rolo, A.P.; Berthiaume, J.; Bjork, J.A.; Wallace, K.B.. "Hyperglycemia decreases mitochondrial function: The regulatory role of mitochondrial biogenesis". Toxicology and Applied Pharmacology 225 2 (2007): 214-220. http://www.scopus.com/inward/record.url?eid=2-s2.0-36048941086&partnerID=MN8TOARS.
    10.1016/j.taap.2007.07.015
  78. Moreira, P.I.; Rolo, A.P.; Sena, C.; Seiça, R.; Oliveira, C.R.; Santos, M.S.. "Insulin attenuates diabetes-related mitochondrial alterations: A comparative study". Medicinal Chemistry 2 3 (2006): 299-308. http://www.scopus.com/inward/record.url?eid=2-s2.0-33746153746&partnerID=MN8TOARS.
    10.2174/157340606776930754
  79. Rolo, A.P.; Palmeira, C.M.. "Diabetes and mitochondrial function: Role of hyperglycemia and oxidative stress". Toxicology and Applied Pharmacology 212 2 (2006): 167-178. http://www.scopus.com/inward/record.url?eid=2-s2.0-33645765312&partnerID=MN8TOARS.
    10.1016/j.taap.2006.01.003
  80. Teodoro, J.; Rolo, A.P.; Oliveira, P.J.; Palmeira, C.M.. "Decreased ANT content in Zucker fatty rats: Relevance for altered hepatic mitochondrial bioenergetics in steatosis". FEBS Letters 580 8 (2006): 2153-2157. http://www.scopus.com/inward/record.url?eid=2-s2.0-33645241135&partnerID=MN8TOARS.
    10.1016/j.febslet.2006.02.078
  81. Palmeira, C.M.; Rolo, A.P.. "Mitochondrially-mediated toxicity of bile acids". Toxicology 203 1-3 (2004): 1-15. http://www.scopus.com/inward/record.url?eid=2-s2.0-4444311570&partnerID=MN8TOARS.
    10.1016/j.tox.2004.06.001
  82. Oliveira, P.J.; Rolo, A.P.; Sardão, V.A.; Monteiro, P.; Gonçalves, L.; Providência, L.A.; Palmeira, C.M.; Moreno, A.J.M.. "Advantages in the use of carvedilol versus propranolol for the protection of cardiac mitochondrial function". Revista Portuguesa de Cardiologia 23 10 (2004): 1291-1298. http://www.scopus.com/inward/record.url?eid=2-s2.0-10644236410&partnerID=MN8TOARS.
  83. Rolo, A.P.; Palmeira, C.M.; Holy, J.M.; Wallace, K.B.. "Role of mitochondrial dysfunction in combined bile acid-induced cytotoxicity: The switch between apoptosis and necrosis". Toxicological Sciences 79 1 (2004): 196-204. http://www.scopus.com/inward/record.url?eid=2-s2.0-2442644019&partnerID=MN8TOARS.
    10.1093/toxsci/kfh078
  84. Oliveira, P.J.; Seica, R.; Santos, D.L.; Rolo, A.P.; Sardao, V.A.; Ferreira, F.M.L.; Palmeira, C.M.; Santos, M.S.; Moreno, A.J.M.. "Vitamin E or coenzyme Q10 administration is not fully advantageous for heart mitochondrial function in diabetic goto kakizaki rats". Mitochondrion 3 6 (2004): 337-345. http://www.scopus.com/inward/record.url?eid=2-s2.0-1942484378&partnerID=MN8TOARS.
    10.1016/j.mito.2004.02.005
  85. Oliveira, P.J.; Esteves, T.; Rolo, A.P.; Palmeira, C.M.; Moreno, A.J.M.. "Carvedilol Inhibits the Mitochondrial Permeability Transition by an Antioxidant Mechanism". Cardiovascular Toxicology 4 1 (2004): 11-20. http://www.scopus.com/inward/record.url?eid=2-s2.0-1942486470&partnerID=MN8TOARS.
    10.1385/CT:4:1:11
  86. Rolo, Anabela P.; Oliveira, Paulo J.; Moreno, Antonio J.; Palmeira, Carlos M.; Rolo, A.P.; Oliveira, P.J.; Moreno, A.J.; Palmeira, C.M.. "Chenodeoxycholate induction of mitochondrial permeability transition pore is associated with increased membrane fluidity and cytochrome c release: protective role of carvedilol". Mitochondrion 2 4 (2003): 305-311. http://dx.doi.org/10.1016/s1567-7249(03)00007-2.
    10.1016/s1567-7249(03)00007-2
  87. Ferreira, F. M.; Oliveira, P. J.; Rolo, A. P.; Santos, M. S.; Moreno, A. J.; da Cunha, M. F.; Seiça, R.; Palmeira, C. M.. "Cholestasis induced by chronic treatment with a-naphthyl-isothiocyanate (ANIT) affects rat renal mitochondrial bioenergetics". Archives of Toxicology 77 4 (2003): 194-200. http://dx.doi.org/10.1007/s00204-003-0441-3.
    10.1007/s00204-003-0441-3
  88. Rolo, A.P.; Palmeira, C.M.; Wallace, K.B.. "Mitochondrially mediated synergistic cell killing by bile acids". Biochimica et Biophysica Acta - Molecular Basis of Disease 1637 1 (2003): 127-132. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037454711&partnerID=MN8TOARS.
    10.1016/S0925-4439(02)00224-7
  89. Oliveira, P.J.; Rolo, A.P.; Seiça, R.; Santos, M.S.; Palmeira, C.M.; Moreno, A.J.. "Reduction in cardiac mitochondrial calcium loading capacity is observable during a-naphthylisothiocyanate-induced acute cholestasis: A clue for hepatic-derived cardiomyopathies?". Biochimica et Biophysica Acta - Molecular Basis of Disease 1637 1 (2003): 39-45. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037454702&partnerID=MN8TOARS.
    10.1016/S0925-4439(02)00212-0
  90. Oliveira, P.J.; Seiça, R.; Coxito, P.M.; Rolo, A.P.; Palmeira, C.M.; Santos, M.S.; Moreno, A.J.M.. "Enhanced permeability transition explains the reduced calcium uptake in cardiac mitochondria from streptozotocin-induced diabetic rats". FEBS Letters 554 3 (2003): 511-514. http://www.scopus.com/inward/record.url?eid=2-s2.0-0242541631&partnerID=MN8TOARS.
    10.1016/S0014-5793(03)01233-X
  91. Palmeira, C.M.; Ferreira, F.M.; Rolo, A.P.; Oliveira, P.J.; Santos, M.S.; Moreno, A.J.; Cipriano, M.A.; Martins, M.I.; Seiça, R.. "Histological changes and impairment of liver mitochondrial bioenergetics after long-term treatment with a-naphthyl-isothiocyanate (ANIT)". Toxicology 190 3 (2003): 185-196. http://www.scopus.com/inward/record.url?eid=2-s2.0-0042133192&partnerID=MN8TOARS.
    10.1016/S0300-483X(03)00163-X
  92. Rolo, A.P.; Oliveira, P.J.; Moreno, A.J.M.; Pameira, C.M.. "Protection against post-ischemic mitochondrial injury in rat liver by silymarin or TUDC". Hepatology Research 26 3 (2003): 217-224. http://www.scopus.com/inward/record.url?eid=2-s2.0-0042167601&partnerID=MN8TOARS.
    10.1016/S1386-6346(03)00108-6
  93. Destainville, A.; Rolo, A.; Champion, E.; Bernache-Assollant, D.. "Synthesis and characterization of beta tricalcium phosphate". Key Engineering Materials 240-242 (2003): 489-492. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037247010&partnerID=MN8TOARS.
  94. Oliveira, P.J.; Esteves, T.; Rolo, A.P.; Monteiro, P.; Gonçalves, L.; Palmeira, C.M.; Moreno, A.J.. "Carvedilol: Relation between antioxidant activity and inhibition of the mitochondrial permeability transition". Revista Portuguesa de Cardiologia 22 1 (2003): 55-62. http://www.scopus.com/inward/record.url?eid=2-s2.0-0346034614&partnerID=MN8TOARS.
  95. Oliveira, P.J.; Rolo, A.P.; Seiça, R.; Santos, M.S.; Palmeira, C.M.; Moreno, A.J.. "Chronic cholestasis and cardiac mitochondrial function in wistar rats: A model for cardiovascular alterations in chronic liver disease?". Revista Portuguesa de Cardiologia 22 1 (2003): 67-75. http://www.scopus.com/inward/record.url?eid=2-s2.0-0344951202&partnerID=MN8TOARS.
  96. Oliveira, P.J.; Rolo, A.P.; Seiça, R.; Santos, M.S.; Palmeira, C.M.; Moreno, A.J.M.. "Cardiac mitochondrial calcium loading capacity is severely affected after chronic cholestasis in Wistar rats". Journal of Investigative Medicine 51 2 (2003): 86-94. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037338705&partnerID=MN8TOARS.
  97. Rolo, A.P.; Oliveira, P.J.; Seiça, R.; Santos, M.S.; Moreno, A.J.; Palmeira, C.M.. "Improved efficiency of hepatic mitochondrial function in rats with cholestasis induced by an acute dose of a-naphthylisothiocyanate". Toxicology and Applied Pharmacology 182 1 (2002): 20-26. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036070550&partnerID=MN8TOARS.
    10.1006/taap.2002.9434
  98. Rolo, A.P.; Palmeira, C.M.; Wallace, K.B.. "Interactions of combined bile acids on hepatocyte viability: Cytoprotection or synergism". Toxicology Letters 126 3 (2002): 197-203. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037033967&partnerID=MN8TOARS.
    10.1016/S0378-4274(01)00464-7
  99. Oliveira, P.J.; Rolo, A.P.; Seiça, R.; Sardão, V.; Monteiro, P.; Gonçalves, L.; Providência, L.; et al. "Impact of diabetes on induction of the mitochondrial permeability transition.". Revista portuguesa de cardiologia : orgão oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 21 6 (2002): 759-766. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036616238&partnerID=MN8TOARS.
  100. Oliveira, P.J.; Rolo, A.P.; Monteiro, P.; Conçalves, L.; Palmeira, C.M.; Moreno, A.J.. "Impact of carvedilol on the mitochondrial damage induced by hypoxanthine and xantine oxidase - What role in myocardial ischemia and reperfusion?". Revista Portuguesa de Cardiologia 21 12 (2002): 1447-1455. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036998602&partnerID=MN8TOARS.
  101. Rolo, A.P.; Oliveira, P.J.; Seiça, R.; Santos, M.S.; Moreno, A.J.; Palmeira, C.M.. "Disruption of mitochondrial calcium homeostasis after chronic a-naphthylisothiocyanate administration: Relevance for cholestasis". Journal of Investigative Medicine 50 3 (2002): 193-200. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036092085&partnerID=MN8TOARS.
  102. Oliveira, P.J.; Rolo, A.P.; Palmeira, C.M.; Moreno, A.J.M.. "Carvedilol reduces mitochondrial damage induced by hypoxanthine/xanthine oxidase: Relevance to hypoxia/reoxygenation injury". Cardiovascular Toxicology 1 3 (2001): 205-213. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035750084&partnerID=MN8TOARS.
    10.1385/CT:1:3:205
  103. Rolo, A.P.; Oliveira, P.J.; Moreno, A.J.M.; Palmeira, C.M.. "Chenodeoxycholate is a potent inducer of the permeability transition pore in rat liver mitochondria". Bioscience Reports 21 1 (2001): 73-80. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034899577&partnerID=MN8TOARS.
    10.1023/A:1010438202519
  104. Rolo, A.P.; Oliveira, P.J.; Moreno, A.J.M.; Palmeira, C.M.. "Protective effect of carvedilol on chenodeoxycholate induction of the permeability transition pore". Biochemical Pharmacology 61 11 (2001): 1449-1454. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035370544&partnerID=MN8TOARS.
    10.1016/S0006-2952(01)00620-7
  105. Oliveira, P.J.; Rolo, A.P.; Sardão, V.A.; Coxito, P.M.; Palmeira, C.M.; Moreno, A.J.M.. "Carvedilol in heart mitochondria - Protonophore or opener of the mitochondrial KATP channels?". Life Sciences 69 2 (2001): 123-132. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035371154&partnerID=MN8TOARS.
    10.1016/S0024-3205(01)01109-2
  106. Oliveira, P.J.; Coxito, P.M.; Rolo, A.P.; Santos, D.L.; Palmeira, C.M.; Moreno, A.J.M.. "Inhibitory effect of carvedilol in the high-conductance state of the mitochondrial permeability transition pore". European Journal of Pharmacology 412 3 (2001): 231-237. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035793307&partnerID=MN8TOARS.
    10.1016/S0014-2999(01)00745-2
  107. Oliveira, P.J.; Rolo, A.P.; Seiãça, R.; Palmeira, C.M.; Santos, M.S.; Moreno, A.J.M.. "Decreased susceptibility of heart mitochondria from diabetic GK rats to mitochondrial permeability transition induced by calcium phosphate". Bioscience Reports 21 1 (2001): 45-53. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034905572&partnerID=MN8TOARS.
  108. Rolo, A.P.; Palmeira, C.M.. "Cholestasis and mitochondrial dysfunction: A review". Toxic Substance Mechanisms 19 2 (2000): 83-98. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034458883&partnerID=MN8TOARS.
    10.1080/10769180052008878
  109. Rolo, A.P.; Oliveira, P.J.; Moreno, A.J.M.; Palmeira, C.M.. "Bile acids affect liver mitochondrial bioenergetics: Possible relevance for cholestasis therapy". Toxicological Sciences 57 1 (2000): 177-185. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033852206&partnerID=MN8TOARS.
Capítulo de livro
  1. Teodoro, João Soeiro; Rolo, Anabela Pinto; Palmeira, Carlos Manuel Marques. "Mitochondrial Bioenergetic Assays as a Standard Protocol for Toxicological and Metabolic Assessment". In Methods in Molecular Biology, 231-241. Springer US, 2021.
    10.1007/978-1-0716-1091-6_16
  2. Teodoro, João S.; Machado, Ivo F.; Palmeira, Carlos M.; Rolo, Anabela P.. "Determination of Oxidative Phosphorylation Complexes Activities". In Methods in Molecular Biology, 17-31. Springer US, 2021.
    10.1007/978-1-0716-1433-4_2
  3. Rolo AP. "Evaluation of mitochondrial membrane potential using fluorescent dyes or a membrane-permeable cation (TPP+) electrode in isolated mitochondria and intact cells". In Immunometabolism: Methods and Protocols. Springer, 2020.
    No prelo
  4. Amorim, Joao Alves; Teodoro, Joao Soeiro; Palmeira, Carlos Marques; Rolo, Anabela Pinto. "Sirtuins and Bile Acids: Potential Anti-obesity Strategies Targeting Mitochondria". In Anti-Obesity Drug Discovery and Development: Volume 4, 57-97. BENTHAM SCIENCE PUBLISHERS, 2018.
    10.2174/9781681085586118040005
  5. Alexandrino, Henrique; Rolo, Anabela; Tralhão, José Guilherme; Castro e Sousa, Francisco; Palmeira, Carlos. "Mitochondria in Liver Regeneration: Energy Metabolism and Posthepatectomy Liver Dysfunction". In Mitochondrial Biology and Experimental Therapeutics, 127-152. Springer International Publishing, 2018.
    Publicado • 10.1007/978-3-319-73344-9_8
  6. Teodoro, João S.; Duarte, Filipe V.; Rolo, Anabela P.; Palmeira, Carlos M.. "Mitochondria as a Target for Safety and Toxicity Evaluation of Nutraceuticals". In Nutraceuticals, 387-400. Elsevier, 2016.
    10.1016/b978-0-12-802147-7.00028-0
  7. Duarte, Filipe V.; Palmeira, Carlos M.; Rolo, Anabela P.. "The Emerging Role of MitomiRs in the Pathophysiology of Human Disease". In Advances in Experimental Medicine and Biology, 123-154. Springer International Publishing, 2015.
    10.1007/978-3-319-22671-2_8
  8. Teodoro, João S.; Palmeira, Carlos M.; Rolo, Anabela P.. "Determination of Oxidative Phosphorylation Complexes Activities". In Methods in Molecular Biology, 71-84. Springer New York, 2015.
    10.1007/978-1-4939-1875-1_7
  9. Palmeira, Carlos M.; Duarte, Filipe V.; Teodoro, João S.; Varela, Ana T.; Rolo, Anabela P.. "Biomarkers of mitochondrial dysfunction and toxicity". In Biomarkers in Toxicology, 847-861. Elsevier, 2014.
    10.1016/b978-0-12-404630-6.00051-8
Edição de número de revista
  1. Rolo AP. "Metabolic Diseases: Drugs and Mitochondrial Targets". Current Medicinal Chemistry (2015):
    Publicado • 10.2174/092986732220150722123617
Livro
  1. Palmeira, C.M.; Rolo, A.P.. Mitochondrial Regulation: Methods and Protocols. Springer. 2015.
    Publicado • 10.1007/978-1-4939-1875-1 • Editor
Atividades

Orientação

Título / Tema
Papel desempenhado
Curso (Tipo)
Instituição / Organização
2021 - Atual Role of epigenetic remodelling in liver regeneration
Orientador
Biociências (Doutoramento)
2020/09 - 2021/11 The role of Sestrin-2 in cellular adaptation to hypoxic stress
Orientador
Cellular and Molecular Biology (Mestrado)
Universidade de Coimbra, Portugal
2020 - 2021 The potential role of sestrin 2 in liver regeneration
Orientador
Universidade de Coimbra, Portugal
2020 - 2020 Programa Estágios de Verão - Gabinete de Saídas Profissionais da Universidade de Coimbra
Orientador
2020 - 2020 Programa Estágios de Verão - Gabinete de Saídas Profissionais da Universidade de Coimbra
Orientador
2020 - 2020 Sestrin2 and mitochondrial quality control: potential impact in myogenic differentiation
Orientador
Universidade de Coimbra, Portugal
2019 - 2019 Sestrina 2 e modulação da função mitocondrial
Orientador
2018 - 2019 Modulation of complex I and oxidative capacity in cells under metabolic stress: the crosstalk between miR-378 and metformin
Orientador
Biologia Celular e Molecular (Mestrado)
Universidade de Coimbra, Portugal
2015 - 2019 Understanding the underlying mechanisms regulating aging and longevity
Coorientador
Biociências (Doutoramento)
Universidade de Coimbra, Portugal
2014 - 2019 Detoxification of fuel oversupply in WAT through metabolic futile cycling induced by bile acids
Coorientador
Universidade de Coimbra, Portugal
2018 - 2018 Programa Estágios de Verão - Gabinete de Saídas Profissionais da Universidade de Coimbra
Orientador
Universidade de Coimbra, Portugal
2018 - 2018 Efeitos da metformina na mitofagia, função mitocondrial e metabolismo dos mioblastos C2C12
Orientador
2017 - 2018 Effects of blueberry juice on the evolution of hepatic dysfunction in an animal model of prediabetes
Coorientador
Bioquímica
Universidade de Coimbra, Portugal
2017 - 2017 Mitohormesis como estratégia terapêutica – expressão de mitoDsRed em células C2C12 para otimização do modelo experimental
Orientador
2016 - 2017 The role of dynamins and dynamin-related protein 1 (Drp 1) in the regulation of mitochondrial and peroxisomal fission
Coorientador
Biologia Celular e Molecular (Mestrado)
Universidade de Coimbra, Portugal
2016 - 2017 Sestrin 2-mediated mitophagy: potential regulation of mitohormesis and promotion of metabolic health
Orientador
Biologia Celular e Molecular (Mestrado)
Universidade de Coimbra, Portugal
2016 - 2017 Effects of bariatric surgery on glycation and vascular remodeling in an obese diabetic animal model
Coorientador
Bioquímica (Mestrado)
Universidade de Coimbra, Portugal
2016 - 2017 Alteration of dopaminergic signaling after carotid body denervation in the modulation of adipose tissue function in the metabolic syndrome
Coorientador
2016 - 2016 Programa Estágios de Verão - Gabinete de Saídas Profissionais da Universidade de Coimbra
Orientador
Universidade de Coimbra, Portugal
2014 - 2015 Remodeling of white adipose tissue and metabolic disease
Orientador
Bioquímica (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2014 - 2015 Dissecting signaling pathways that control glia migration in the developing Drosophila retina
Coorientador
Biologia Molecular e Celular (Mestrado)
Universidade de Aveiro Departamento de Biologia, Portugal
2014 - 2015 Role of the sphingomyelinase Isc1p in the regulation of iron homeostasis in Saccharomyces cerevisiae
Coorientador
Biologia Molecular e Celular (Mestrado)
Universidade de Aveiro Departamento de Biologia, Portugal
2014 - 2015 O efeito pro´-carcinoge´nico do 17ß-estradiol na captac¸a~o de nutrientes essenciais para as ce´lulas MCF-7
Coorientador
Biologia Molecular e Celular (Mestrado)
Universidade de Aveiro Departamento de Biologia, Portugal
2014 - 2015 Characterization of the glial scar tissue in a murine model of spinal cord compression, with focus on hyaluronan
Coorientador
Biologia Molecular e Celular (Mestrado)
Universidade de Aveiro Departamento de Biologia, Portugal
2014 - 2015 Dissecting the role of Profilin-1 in microglial cell function: the impacto n reactive oxygen species production
Coorientador
Biologia Molecular e Celular (Mestrado)
Universidade de Aveiro Departamento de Biologia, Portugal
2014 - 2015 Modulation of mitochondrial stress response by Sestrin 2
Orientador
Biologia Molecular e Celular (Mestrado)
Universidade de Aveiro Departamento de Biologia, Portugal
2014 - 2014 Modulação do ciclo TG/ (GL+ FFA) como alvo terapêutico na obesidade
Orientador
Biologia Molecular e Celular (Mestrado)
Universidade de Aveiro, Portugal
2012 - 2012 Efeito do 3-bromopiruvato na pluripotência de células estaminais embrionárias
Coorientador
Biologia Molecular e Celular (Mestrado)
Universidade de Aveiro, Portugal
2008 - 2012 Regulation of mitochondrial function in ischemia/reperfusion: looking for therapeutic strategies in fatty livers
Coorientador
Biologia (Doutoramento)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2008 - 2012 Unravelling new roles for SIRT1 in mitochondrial biology
Coorientador
Biologia (Doutoramento)
Universidade de Coimbra, Portugal
2007 - 2012 Physiologic pathways and molecular mechanisms regulating energy homeostasis in diabetes
Coorientador
Biociências (Doutoramento)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2007 - 2012 Dibenzofuran exposure: cellular and mitochondrial damage
Coorientador
Biociências (Doutoramento)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2009 - 2010 Efeitos do tratamento com berberina na sinalização por AMPK e estimulação da função mitocondrial num modelo de obesidade induzida por dieta
Coorientador
Biologia Celular e Molecular (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2009 - 2009 Efeito da metformina na função mitocondrial diabética
Coorientador
Biologia Animal (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2009 - 2009 O efeito do UDCA na terapia anti-colestática: relevância para a função mitocondrial
Coorientador
Biologia Animal (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2007 - 2008 Efeitos do Chitosan na função mitocondrial hepática de ratos Goto-Kakizaki
Coorientador
Biologia (Licenciatura/Bacharelato)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2007 - 2008 Indirubina altera a fosforilação oxidativa mitocondrial e previne a indução de permeabilidade transitória
Coorientador
Biologia (Licenciatura/Bacharelato)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2006 - 2007 Alteração da função mitocondrial como consequência da exposição a dioxinas e outros poluentes ambientais
Coorientador
Biologia (Licenciatura/Bacharelato)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2006 - 2007 Tolerância mitocondrial e pré-condicionamento isquémico: importância na prevenção da lesão hepática induzida por isquémia-reperfusão
Coorientador
Biologia (Licenciatura/Bacharelato)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2006 - 2007 Alteração da função mitocondrial em patologias pulmonares: consequências da exposição a dioxinas e outros poluentes ambientais
Coorientador
Bioquímica (Licenciatura/Bacharelato)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2006 - 2007 Esteatose hepática: mecanismos celulares com relevância na função mitocondrial
Coorientador
Biologia Celular (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2005 - 2006 Toxicidade renal de ácidos biliares ao nível do metabolismo mitocondrial
Coorientador
Biologia (Licenciatura/Bacharelato)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2004 - 2005 Disfunção mitocondrial na esteatose hepática
Coorientador
Biologia (Licenciatura/Bacharelato)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal

Participação em evento

Descrição da atividade
Tipo de evento
Nome do evento
Instituição / Organização
2020/01/21 - 2020/01/21 Oficina BCM nas escolas – Gabinete de Apoio à Divulgação da Universidade de Coimbra. Atividades teórico-práticas no âmbito da Biologia Celular e Molecular para alunos do 11o ano na Escola Secundária Lima de Faria – Cantanhede.
Oficina (workshop)
Universidade de Coimbra, Portugal
2019/05/22 - 2019/05/24 Machado I, Palmeira CM, Rolo AP. Modulation of complex I and oxidative capacity in cells under metabolic stress
Congresso
53rd Annual Meeting of the European Society for Clinical Investigation
2019/05/22 - 2019/05/24 Teodoro J, Rolo A, Silva R, Machado I, Rosello-Catafau J, Steegborn C, Palmeira C. Novel avenues of ischemia/reperfusion injury pervention: lessons from a soluble adenylyl cyclase inhibitor and a SirT3 activator. MitoPorto 2019 - International Symposium of the Consortium for Mitochondrial Research
2019/01/18 - 2019/01/18 Oficina BCM nas escolas – Gabinete de Apoio à Divulgação da Universidade de Coimbra. Atividades teórico-práticas no âmbito da Biologia Celular e Molecular para alunos do 11o ano na Escola Básica e Secundária Dr. Pascoal José de Melo – Ansião.
Oficina (workshop)
Universidade de Coimbra, Portugal
2019/01/14 - 2019/01/14 Oficina BCM nas escolas – Gabinete de Apoio à Divulgação da Universidade de Coimbra. Atividades teórico-práticas no âmbito da Biologia Celular e Molecular para alunos do 11o ano na Escola Secundária Lima de Faria – Cantanhede.
Oficina (workshop)
Universidade de Coimbra, Portugal
2019 - 2019 Atividades na área do saber – Universidade de Verão 2019 (atividades na área da Biologia Celular e Molecular, dirigidas a alunos do ensino secundário)
Outro
Universidade de Coimbra, Portugal
2018/11/14 - 2018/11/18 Amorim J, Tackur S, Bonkowski MS, Rolo AP, Palmeira CM, Sinclair DA. A new mouse model to unravel the mechanism of SIRT1 activation.
Congresso
Gerontological Society of America Annual Meeting
2018/11/07 - 2018/11/07 Amorim J, Tackur S, Bonkowski MS, Rolo AP, Palmeira CM, Sinclair DA. An activation-defective mouse mutant as a model to unravel the mechanisms of SIRT1 activators Fourth Annual Northeast Glenn Foundation Symposium on the Biology of Aging (New Haven, EUA, 7 de novembro de 2018)
2018/10/01 - 2018/10/05 Amorim J, Tackur S, Bonkowski MS, Rolo AP, Palmeira CM, Sinclair DA. An activation-defective mouse mutant as a model to unravel the mechanisms of SIRT1 activators. Cold Spring Harbor Laboratory: Mechanisms of Aging (Cold Spring Harbor, EUA, 1- 5 de outubro de 2018)
2018/06/19 - 2018/06/20 Nunes S, Castela A, Rolo AP, Palmeira CM, Andre´ MA, Cavadas C, Pintado MM, Reis F. Blueberry juice attenuates liver injury progression in a rat model of diet-induced prediabetes. 1st Meeting in Translational Pharmacology, 38th SEF national meeting/9th SEFF meeting (Santiago de Compostela, Espanha, 19-20 de junho de 2018)
2018/06/04 - 2018/06/07 Teodoro JS, Amorim JA, Silva R, Rolo AP, Steegborn C, Sinclair DA, Palmeira CM. Sirtuin-cAMP crosstalk in metabolic diseases: nucleus versus mitochondria. 19th Biennial Meeting of the Society for Free Radical Research International (Lisboa, 4-7 de junho de 2018)
2018/05/30 - 2018/06/01 Teodoro JS, Rolo AP, Carvalho RA, Palmeira CM. Exploring the role of the bile acid receptor TGR5 in bile acid mediated obesity control: Novel insights from a CRISPR/Cas9 adipocyte model. 52nd Annual Meeting of the European Society for Clinical Investigation (Barcelona, Espanha, 30 de maio - 1 de junho de 2018)
2018/03/08 - 2018/03/10 Martins R, Teodoro J, Rolo A, Furtado E, Palmeira C, Tralha~o JG. Novos fatores de progno´stico precoces na transplantac¸a~o hepa´tica: avaliac¸a~o bioenerge´tica e da func¸a~o mitocondrial. XXXVIII Congresso Nacional de Cirurgia (Lisboa, 8-10 de marc¸o de 2018)
2018 - 2018 Dia de Investigação do DCV 2018
Outro
Universidade de Coimbra, Portugal
2018 - 2018 Atividades na área do saber – Universidade de Verão 2018 (atividades na área da Biologia Celular e Molecular, dirigidas a alunos do ensino secundário)
Outro
2017/05/17 - 2017/05/20 Alexandrino A, Teodoro JS, Donato H, Martins R, Sero^dio M, Martins M, Rolo A, Tralha~o JG, Palmeira C, Castro e Sousa F. Mitochondrial bioenergetics and biogenesis are involved in the regenerative response of the human liver in two-stage hepatectomies. 51st Annual Meeting of the European Society for Clinical Investigation (Ge´nova, Ita´lia, 17-20 de maio de 2017)
2017/03/30 - 2017/04/01 Alexandrino A, Teodoro JS, Donato H, Martins R, Sero^dio M, Martins M, Rolo A, Tralha~o JG, Palmeira C, Castro e Sousa F. Metabolismo Energe´tico nas Hepatectomia a Dois Tempos: Adaptac¸a~o da Func¸a~o Mitocondrial como Feno´meno Central na Regenerac¸a~o Hepa´tica. Congresso Portugue^s de Hepatologia (Porto, 30-1 de Abril de 2017)
2017/03/16 - 2017/03/18 Martins R, Teodoro J, Rolo A, Furtado E, Palmeira C, Tralha~o JG. Avaliac¸a~o da efica´cia do R5 na preservac¸a~o da atividade mitocondrial na transplantac¸a~o hepa´tica. XXXVII Congresso Nacional de Cirurgia (Figueira da Foz, 16-18 de marc¸o de 2017)
2017 - 2017 Dia de Investigação do DCV 2017
Outro
Universidade de Coimbra, Portugal
2016/10/24 - 2016/10/26 Alexandrino A, Teodoro JS, Donato H, Martins R, Sero^dio M, Martins M, Rolo A, Tralha~o JG, Palmeira C, Castro e Sousa F. Bioenergetic adaptations of the human liver in two-stage hepatectomy with portal vein ligation – how liver regeneration correlates with mitochondrial energy status. 7th World Congress on Targeting Mitochondria (Berlim, Alemanha, 24-26 de outubro de 2016)
2016/10/13 - 2016/10/15 Martins R, Teodoro J, Rolo A, Furtado E, Palmeira C, Tralha~o JG. Avaliac¸a~o da efica´cia do RM3365 na preservac¸a~o da atividade mitocondrial na transplantac¸a~o hepa´tica. XIII Congresso Portugue^s de Transplantac¸a~o/ XV Congresso Luso Brasileiro de Transplantac¸a~o/ II Encontro Ibe´rico de Transplantac¸a~o (Porto, 13-15 de outubro, 2016)
2016/10/02 - 2016/10/09 Pereira LC, Duarte FV, Varela AT, Rolo AP, Palmeira CMM, Dorta DJ. Autophagic process is activated in BDE-153-induced toxicity. 14th International Congress of Toxicology (Merida, Me´xico, 2-9 de outubro de 2016)
2016/04/27 - 2016/04/29 Teodoro JS, Varela AT, Duarte FV, Rolo AP, Palmeira CM. Prevention of hepatic ischemia/reperfusion damage in a surgical context: The key role of preservation of mitochondrial function. 50th Annual Scientific Meeting of the European Society for Clinical Investigation (Paris, Franc¸a, 27-29 de abril de 2016)
2016/03/03 - 2016/03/05 Martins R, Teodoro J, Rolo A, Furtado E, Palmeira C, Tralhãoo JG. Liver transplantation: evaluation of mitochondrial activity in animal model. XXXVI Congresso Nacional de Cirurgia (Lisboa, 3-5 de marc¸o de 2016)
2016 - 2016 Ciência Viva no Laboratório
Oficina (workshop)
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2015/09/13 - 2015/09/16 Silva MP, Pereira, LC, Duarte FV, Rolo AP, Palmeira CMM, Dorta DJ. Brominated flame retardant (BDE-47) induces autophagic processes in HepG2 cells. 51st Congress of the European Societies of Toxicology (Porto, 13-16 de setembro de 2015)
2015/09/13 - 2015/09/16 Panzani E, Bejaoui M, Folch-Puy E, Rolo AP, Palmeira CM, Gerousi M, Rosello-Catafau J. Angiotensin II type 1 receptor inhibition and SIRT1 activation in rat reduced- size orthotopic liver transplantation. 17th Congress of the European Society for Organ Transplantation (Bruxelas, Be´lgica, 13-16 de setembro de 2015)
2015/05/27 - 2015/05/30 Varela AT, Duarte FV, Teodoro JS, Gomes AP, Palmeira CM, Rolo AP. Novel strategies to prevent ischemia/reperfusion damage in fatty liver surgery: The effects of NAD(+) and indirubin on mitochondrial function. 49th Annual Scientific Meeting of the European Society for Clinical Investigation (Cluj-Napoca, Rome´nia, 27-30 de maio de 2015)
2015/03/05 - 2015/03/07 Alexandrino H, Varela AT, Oliveira RC, Cardoso J, Duarte FV, Teodoro JS, Rolo A, Cipriano MA, Tralha~o JG, Prado e Castro L, Palmeira C, Castro e Sousa F. Hepatotoxicidade da Quimioterapia: Validac¸a~o de um Modelo Animal. XXXV Congresso Nacional de Cirurgia (Figueira da Foz, 5-7 de marc¸o de 2015)
2015/02/13 - 2015/02/14 Alexandrino A, Varela AT, Ferreira L, Martins R, Duarte FV, Teodoro JS, Serôdio M, Martins M, Rolo A, Tralhão JG, Palmeira C, Castro e Sousa F. Função Mitocondrial: Factor Relevante na Disfunção Hepatocelular pós-Hepatectomia? Congresso Português de Hepatologia (Lisboa, 13-14 de fevereiro de 2015)
2015 - 2015 Ciência Viva no Laboratório
Oficina (workshop)
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2014 - 2014 The effects of Berberine on high fat-fed hepatic rat mitochondrial function: a possible role for Sirt3
Encontro
48th Annual Scientific Meeting of the European Society for Clinical Investigation (ESCI)
European Society for Clinical Investigation, Países Baixos
2014 - 2014 The Mitochondrial Effects of a Chronic Exposure to a Low-Dose of Silver Nanoparticles Are Rescued by an Antioxidant
Encontro
53rd Meeting of the Society of Toxicology
Society of Toxicology, Estados Unidos
2014 - 2014 Mitochondria in glutamatergic nerve terminals are selectively affected by exposure to Aß1-42 modeling early Alzheimer's disease
Conferência
International Bordeaux Neurocampus / Brain Conference
Fédération Bordeaux Neurocampus, França
2014 - 2014 Exposure to silver nanoparticles: can the mitochondrial damage be rescued by an antioxidant?
Congresso
XVIII Congress of the Portuguese Biochemical Society
Sociedade Portuguesa de Bioquímica, Portugal
2014 - 2014 "Pergunta-me Ciência"
Oficina (workshop)
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2014 - 2014 "Pergunta-me Ciência"
Oficina (workshop)
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2012 - 2012 SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function
Simpósio
Keystone Symposia on Molecular and Cellular Biology: Sirtuins in Metabolism, Aging and Disease
Keystone Symposia, Estados Unidos
2012 - 2012 Potential Role of SIRT1 preventing mitochondrial dysfunction by maintaining the balance between nuclear and mitochondrial ETC components
Simpósio
Keystone Symposia on Molecular and Cellular Biology: Sirtuins in Metabolism, Aging and Disease
Keystone Symposia, Estados Unidos
2012 - 2012 New insights into the role of sirtuins in aging and age-related diseases
Simpósio
Keystone Symposia on Molecular and Cellular Biology: Sirtuins in Metabolism, Aging and Disease
Keystone Symposia, Estados Unidos
2011 - 2011 Generation of an inducible wholebody SIRT1 knockout mouse to probe the mechanisms by which SIRT1 and Resveratrol improve metabolic function
Conferência
Cell Symposia: Metabolism & Aging Conference
2011 - 2011 Modulation of adenosine receptors as regulatory elements in preconditioning
Congresso
2nd World Congress on Targeting Mitochondria
2011 - 2011 Dibenzofuran-Induced Mitochondrial Dysfunction: Effects of ANT Interaction
Congresso
2nd World Congress on Targeting Mitochondria
2011 - 2011 “Hyperglycemic Memory”: Permanent Cellular Damage in a Transient Insult - A Mitochondrial Perspective
Congresso
2nd World Congress on Targeting Mitochondria
2010 - 2010 Generation of inducible whole body SIRT1 knockout mice to avoid developmental defects and test the effects of pharmacological SIRT1 activation
Conferência
Molecular genetics of Aging, Cold Spring Harbour Laboratories
Cold Spring Harbor Laboratory, Estados Unidos
2010 - 2010 Berberine administration stimulates mitochondrial function in a model of diet-induced obesity
Conferência
Targeting Mitochondria
2010 - 2010 Mitochondrial-mediated Dibenzofuran toxicity
Congresso
XVII National Congress of Biochemistry
Sociedade Portuguesa de Bioquímica, Portugal
2010 - 2010 AMPK signaling regulated by Berberine and stimulation of mitochondria function in a model of diet-induced obesity
Congresso
XVII National Congress of Biochemistry
Sociedade Portuguesa de Bioquímica, Portugal
2010 - 2010 Decreased ANTCypD interaction is associated with the protective effect of indirubin in hepatic preconditioning
Congresso
XVII National Congress of Biochemistry
Sociedade Portuguesa de Bioquímica, Portugal
2009/04/01 - 2009/04/04 Rosiglitazone/Metformin increases mitochondrial biogenesis in Goto-Kakizaki rats: Bioenergetic consequences for diabetes
Congresso
3rd International Congress on Prediabetes and the Metabolic Syndrome
2009 - 2009 Rosiglitazone/Metformin (Avandamet) increases mitochondrial biogenesis in Goto-Kakizaki rats: Bioenergetic consequences for diabetes
Conferência
EMBO Lecture Course in Mitochondrial Medicine: from genetics to biological mechanisms and beyond
2009 - 2009 Dibenzofuraninduced mitophagy plays an important role on the inhibition of lung cells proliferation
Conferência
EMBO Lecture Course in Mitochondrial Medicine: from genetics to biological mechanisms and beyond
2009 - 2009 Indirubin-3´-oxime prevents hepatic I/R damage by inhibiting GSK-3beta; and mitochondrial permeability transition
Conferência
EMBO Lecture Course in Mitochondrial Medicine: from genetics to biological mechanisms and beyond
2009 - 2009 Rosiglitazone/Metformin (Avandamet) increases mitochondrial biogenesis in Goto-Kakizaki rats: Bioenergetic consequences for diabetes
Conferência
International Courses on Toxicology: “Mitochondria: between life and death”
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2009 - 2009 Dibenzofuraninduced mitophagy plays an important role on the inhibition of lung cells proliferation
Conferência
International Courses on Toxicology: “Mitochondria: between life and death”
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2009 - 2009 Indirubin-3´-oxime prevents hepatic I/R damage by inhibiting GSK-3beta; and mitochondrial permeability transition
Conferência
International Courses on Toxicology: “Mitochondria: between life and death”
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2008/10/22 - 2008/10/25 Indirubin-3´- oxime prevents hepatic I/R damage by inhibiting GSK-3beta and mitochondrial permeability transition
Congresso
XVI National Congress of Biochemistry
Universidade dos Açores Centro de Biotecnologia dos Açores, Portugal
2008/10/22 - 2008/10/25 Rosiglitazone/Metformin (Avandamet) increases mitochondrial biogenesis in Goto-Kakizaki rats: Bioenergetic consequences for diabetes
Congresso
XVI National Congress of Biochemistry
Universidade dos Açores Centro de Biotecnologia dos Açores, Portugal
2008/04/09 - 2008/04/11 Differential alterations in mitochondrial function induced by a choline-deficient diet: understanding fatty liver disease progression
Conferência
International Courses on Toxicology 2008 “Metabolic Toxicology: From Pathway to Organism
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2008/04/09 - 2008/04/11 Exposure to Dibenzofuran affects lung mitochondria bioenergetics and cell proliferation
Conferência
International Courses on Toxicology 2008 “Metabolic Toxicology: From Pathway to Organism
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2008/04/09 - 2008/04/11 Indirubin-3’-oxime impairs mitochondrial oxidative phosphorylation and prevents mitochondrial permeability transition induction
Conferência
International Courses on Toxicology 2008 “Metabolic Toxicology: From Pathway to Organism
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2008/03/16 - 2008/03/20 In vitro assessment of silver nanoparticles toxicity in hepatic mitochondrial function
Encontro
47th Annual Meeting of the Society of Toxicology
Society of Toxicology, Estados Unidos
2008/02/25 - 2008/02/25 Obesity-related alterations in mitochondrial biogenesis and function: implications for metabolic disease
Seminário
Young Scientist Seminar
2007/04/25 - 2007/04/28 Hepatic mitochondrial adenine nucleotide translocator is decreased in Zucker fatty rats: Its potential role for altered mitochondrial bioenergetics in fatty liver disease
Congresso
2nd International Congress on "Prediabetes" and the Metabolic Syndrome
2007/04/25 - 2007/04/28 Differential alterations in mitochondrial function induced by a choline-deficient diet: understanding fatty liver disease progression
Congresso
2nd International Congress on "Prediabetes" and the Metabolic Syndrome
2007/01/14 - 2007/01/19 Hepatic mitochondrial adenine nucleotide translocator is decreased in Zucker fatty rats: Its potential role for altered mitochondrial bioenergetics in fatty liver disease
Conferência
Keystone Symposia on “Obesity: Peripheral and central pathways regulating energy homeostasis”
2006/04/03 - 2006/04/07 Hyperglycemia decreases mitochondrial function: the regulatory role of mitochondrial biogenesis
Conferência
FEBS Advanced Course “Human and microbial genetics: DNA arrays applied to human parhogens and disease”
Federation of European Biochemical Societies, Reino Unido
2006/03/05 - 2006/03/09 Bioenergetic phenotype of NRTI-induced mitochondrial cardiomyopathy
Encontro
45th Annual Meeting of the Society of Toxicology
Society of Toxicology, Estados Unidos
2006/03/05 - 2006/03/09 Hyperglycemia decreases mitochondrial function: the regulatory role of mitochondrial biogenesis
Encontro
45th Annual Meeting of the Society of Toxicology
Society of Toxicology, Estados Unidos
2006/03/05 - 2006/03/09 Mitochondrial adenine nucleotide translocator expression is decreased in liver cells of Zucker fatty rats: relevance for altered mitochondrial bioenergetics in steatosis
Encontro
45th Annual Meeting of the Society of Toxicology
Society of Toxicology, Estados Unidos
2005/03/06 - 2005/03/10 Nucleoside analog reverse transcriptase inhibitor (NRTI)-induced mitochondrial depleted cardiac myocytes
Encontro
44th Annual Meeting of the Society of Toxicology
Society of Toxicology, Estados Unidos
2005/03/06 - 2005/03/10 Hyperglycemia-induced oxidative stress activates the hexosamine pathway and decreases mitochondrial biogenesis
Encontro
44th Annual Meeting of the Society of Toxicology
Society of Toxicology, Estados Unidos
2004/12/02 - 2004/12/04 Mitochondrial dysfunction as a major determinant in bile acids induced cell death
Congresso
XIV Congresso Nacional de Bioquímica
Sociedade Portuguesa de Bioquímica, Portugal
2004/03/21 - 2004/03/25 Chenodeoxycholic acid mediates induction of the mitochondrial permeability transition through altered membrane fluidity
Encontro
43th Annual Meeting of the Society of Toxicology
Society of Toxicology, Estados Unidos
2003/12/04 - 2003/12/06 Hepatic ischemia/reperfusion injury and mitochondrial function: a comparative study between TUDC and silymarin effects
Congresso
6th Portuguese Congress on Free Radicals in Chemistry, Biology and Medicine
2003/08/27 - 2003/08/30 Role of mitochondrial dysfunction in combined bile acids-induced cytotoxicity: the switch between apoptosis and necrosis.
Conferência
FEBS Advanced Course “Poly-ADP-ribosylation in health and disease”
Federation of European Biochemical Societies, Reino Unido
2003/03/09 - 2003/03/13 Mitochondrial mediated cell killing by bile acids
Encontro
41st Annual Meeting of the Society of Toxicology
Society of Toxicology, Estados Unidos
2003/03/09 - 2003/03/13 Role of mitochondrial dysfunction in combined bile acid-induced apoptosis
Encontro
41st Annual Meeting of the Society of Toxicology
Society of Toxicology, Estados Unidos
2002/12/05 - 2002/12/07 Potentiation of cell killing by bile acids is mediated by mitochondrial permeability transition induction
Congresso
XII Congresso Nacional de Bioquímica
Sociedade Portuguesa de Bioquímica, Portugal
2002/09/10 - 2002/09/15 Critical role of mitocondrial protein thiol groups in the inhibitory action of carvedilol on the mitochondrial permeability transition
Conferência
12th European Bioenergetics Conference
2002/04/13 - 2002/04/17 Carvedilol: relação entre a actividade antioxidante e inibição da transição de permeabilidade mitocondria
Congresso
XXIII Congresso Português de Cardiologia
Sociedade Portuguesa de Cardiologia, Portugal
2002/04/13 - 2002/04/17 Mitocôndrias isoladas de cardiomiócitos de ratos com colestase aguda apresentam deficiente acumulação de cálcio
Congresso
XXIII Congresso Português de Cardiologia
Sociedade Portuguesa de Cardiologia, Portugal
2002/04/13 - 2002/04/17 Colestase crónica e mitocôndrias cardíacas: diminuição da tomada de cálcio por indução da transição de permeabilidade
Congresso
XXIII Congresso Português de Cardiologia
Sociedade Portuguesa de Cardiologia, Portugal
2002/04/13 - 2002/04/17 A transição de permeabilidade mitocondrial inibe a tomada de cálcio em mitocôndrias cardíacas de ratos diabéticos
Congresso
XXIII Congresso Português de Cardiologia
Sociedade Portuguesa de Cardiologia, Portugal
2002/04/13 - 2002/04/17 O carvedilol reduz o dano mitocondrial induzido por hipoxantina / xantina oxidase – relevância para a isquémia e reperfusão do miocárdio
Congresso
XXIII Congresso Português de Cardiologia
Sociedade Portuguesa de Cardiologia, Portugal
2002/04/09 - 2002/04/10 Interactions of combined bile acids on hepatocyte viability: cytoprotection or synergism
Encontro
Joint Annual Meeting of the Society of Environmental Toxicology & Chemistry, Midwest Chapter & Society of Toxicology, Northland Chapter
Society of Environmental Toxicology and Chemistry, Estados Unidos

Society of Toxicology, Estados Unidos

American College Of Sports Medicine, Estados Unidos

Medical Library Association, Estados Unidos
2002/03/17 - 2002/03/21 Interactions of combined bile acids on hepatocyte viability: cytoprotection or synergism
Encontro
41st Annual Meeting of the Society of Toxicology
Society of Toxicology, Estados Unidos
2001/09/27 - 2001/09/29 Mitochondria from diabetic rats’ cardiomyocytes are more resistant to the induction of the permeability transition pore
Encontro
2nd European Meeting on Vascular Biology and Medicine
2001/09/02 - 2001/09/07 Chenodeoxycholate induced-mitochondrial dysfunction involves induction of the permeability transition pore: protective effect of carvedilol
Conferência
FEBS Advanced Course “Mitochondrial Role in the Cell Life and Death”
Federation of European Biochemical Societies, Reino Unido
2001/09/02 - 2001/09/07 Carvedilol inhibits the high conductance state of the permeability transition pore in heart mitochondria carvedilol
Conferência
FEBS Advanced Course “Mitochondrial Role in the Cell Life and Death”
Federation of European Biochemical Societies, Reino Unido
2001/05/25 - 2001/05/29 Chenodeoxycholate induced-mitochondrial dysfunction involves induction of the permeability transition pore: protective effect of carvedilol
Encontro
40th Annual Meeting of the Society of Toxicology
Society of Toxicologic Pathology, Estados Unidos
2000/11/09 - 2000/11/11 Decreased susceptibility of heart mitochondria from diabetic GK rats to mitochondrial permeability transition induced by calcium/phosphate
Congresso
II Congresso de Investigação em Bioquímica
2000/09/28 - 2000/09/30 Chenodeoxycholate is a potent inducer of the permeability transition pore in liver mitochondria: its importance in cholestasis development
Congresso
XII Congresso Nacional de Bioquímica
Sociedade Portuguesa de Bioquímica, Portugal
2000/09/28 - 2000/09/30 Carvedilol inhibits the exogenous NADH dehydrogenase in rat heart mitochondria
Congresso
XII Congresso Nacional de Bioquímica
Sociedade Portuguesa de Bioquímica, Portugal
2000/09/28 - 2000/09/30 Carvedilol in heart mitochondria: protonophore or opener of the mitochondrial KATP channels?
Congresso
XII Congresso Nacional de Bioquímica
Sociedade Portuguesa de Bioquímica, Portugal
2000/09/28 - 2000/09/30 Inhibitory effect of carvedilol in the high-conductance state of the calcium-sensitive mitochondrial permeability transition pore
Congresso
XII Congresso Nacional de Bioquímica
Sociedade Portuguesa de Bioquímica, Portugal
2000/04/09 - 2000/04/12 O carvedilol inibe a NADH desidrogenase exógena em mitocôndrias de coração de rato
Congresso
XXI Congresso Português de Cardiologia
Sociedade Portuguesa de Cardiologia, Portugal
2000/04/07 - 2000/04/12 Impairment of mitochondrial function induced by bile acids: relevance for bile acid therapy
Conferência
Mechanisms in Toxicity: EuroConference on New Cellular Targets of Cytotoxic Mechanisms
European Science Foundation, França
2000/04/08 - 2000/04/11 Os cardiomiócitos de ratos diabéticos são mais resistentes à indução da transição de permeabilidade mitocondrial
Congresso
XXII Congresso Português de Cardiologia
Sociedade Portuguesa de Cardiologia, Portugal
2000/03/19 - 2000/03/23 Bile acids affect liver mitochondrial bioenergetics: possible relevance for cholestasis therapy
Congresso
39th Annual Meeting of the Society of Toxicology
2000/03/05 - 2000/03/10 Bile acids affect liver mitochondrial bioenergetics: possible relevance for cholestasis therapy
Conferência
Expression and regulation of mitochondrial oxidative phosphorylation and disorders in human pathology
Federation of European Biochemical Societies, Reino Unido
2000/03/05 - 2000/03/10 Carvedilol inhibits the exogenous NADH dehydrogenase in rat heart mitochondria
Conferência
FEBS Advanced Course “Expression and regulation of mitochondrial oxidative phosphorylation and disorders in human pathology”
Federation of European Biochemical Societies, Reino Unido

Júri de grau académico

Tema
Tipo de participação
Nome do candidato (Tipo de grau)
Instituição / Organização
2020 Avaliação do sistema colinérgico na doença de Alzheimer António José dos Santos Gabriel (Doutoramento)
Universidade de Coimbra, Portugal
2020 Mitochondrial dynamics and mitophagy in cellular models of Parkinson's Disease
Presidente do júri
Bruno Miguel Sequeira dos Santos (Mestrado)
2020 Heavy Metal Exposure And Its Effects In Male Reproductive Health: An In Vivo And In Vitro Study
Arguente principal
Carolina Matos Carola (Mestrado)
2020 Biological activity of Brassica by-products in cell models of oxidative stress and lipid toxicity
Arguente principal
José Pedro Fernandes Castelão Moreira Baptista (Mestrado)
2020 Metabolic modulation in paused-like pluripotency
Vogal
Maria Inês Ramalho de Almeida e Sousa (Doutoramento)
2019 Understanding the underlying mechanisms regulating aging and longevity João Filipe Alves Amorim (Doutoramento)
Universidade de Coimbra, Portugal
2019 Illuminating G protein-coupled receptors: a bioluminescence-based method to photoactivate receptor ligands Ana Carolina Palmeira do Amaral (Mestrado)
Universidade de Coimbra, Portugal
2019 P-cadherin role on the mitochondrial biology of breast cancer cells Margarida Ribeiro da Silva (Mestrado)
Universidade de Coimbra, Portugal
2019 Mitochondrial performance during osteoblast differentiation: searching new targets to counteract osteoporosis Sara Cristiana Alves Valente (Mestrado)
2019 Modulation of complex I and oxidative capacity in cells under metabolic stress: the interplay between miR-378a-3p and metformin Ivo Manuel Ferreira Machado (Mestrado)
Universidade de Coimbra, Portugal
2019 Effect of dual therapy with liraglutide and ghrelin on brain metabolism and intracellular stress in the Huntington's disease R6/2 mouse model Débora Tatiana de Sousa Mena (Mestrado)
Universidade de Coimbra, Portugal
2019 Role of the Adenine Nucleotide Translocator 2 in P19 Embryonal Carcinoma Stem Cells Mitochondrial Profile Gabriela Lopes Oliveira (Mestrado)
Universidade de Coimbra, Portugal
2019 Uncover the mechanism behind miRNA function on cell survival Marta Filipa Viegas Barão (Mestrado)
Universidade de Coimbra, Portugal
2018/09/12 Investigation of genes associated to mitochondrial import and post-translational processing in LHON Márcia Joana Nascimento Teixeira (Mestrado)
Universidade de Coimbra, Portugal
2018 Liver transplantation: new prognostic factors of the regulation of mitochondrial function in ischemia/reperfusion Rui Miguel Rua Filipe Martins (Doutoramento)
Universidade de Coimbra, Portugal
2017/07/18 O-GlcNAcylation represents a “sweet” route to tackle Alzheimer’s disease-related phenotype Tiffany Santos Pinho (Mestrado)
Universidade de Coimbra, Portugal
2017/07/17 Neuronal energy status and Alzheimer's disease: searching for a connection Diogo Miguel Matos Vila Verde (Mestrado)
Universidade de Coimbra, Portugal
2017 O papel do sistema adenosinérgico em modelos animais de estresse crónico e depressão Nuno Miguel de Jesus Machado (Doutoramento)
Universidade de Coimbra, Portugal
2017 O-GlcNAcylation represents a “sweet” route to tackle Alzheimer’s disease-related phenotype Tiffany Santos Pinho (Mestrado)
Universidade de Coimbra, Portugal
2016/11/17 Modulatory effect of dietary pattern, exercise and atorvastatin treatment on eNos, sirtuins and miR-155 expression in the erectile tissue of the aged rat Bárbara Sofia Ferreira da Rocha (Mestrado)
Universidade do Porto Faculdade de Medicina, Portugal
2016 Functional investigation of OXPHOS assembly factors in Leber's Hereditary optic Neuropathy (LHON) Maria Inês Arêlo Manso da Fonseca (Mestrado)
Universidade de Coimbra, Portugal
2016 Efeito da cirurgia bariática na função endotelial associada à diabetes tipo 2 Diana Cristina Miguel Ribeiro (Mestrado)
Universidade de Coimbra, Portugal
2016 Avaliação dos mecanismos moleculares de resistência a hipometilantes em Leucemia Mieloide Aguda Patrícia Isabel Martins Corredeira (Mestrado)
Universidade de Coimbra, Portugal
2016 Endothelial cell's response to proteostatic dysregulation: pursuing the protective action of ghrelin Daniela Alexandra Dinis Costa (Mestrado)
Universidade de Coimbra, Portugal
2016 The importance of cytokinesmediated communication in CSCs’ formation Marco Rafael Lopes da Cunha (Mestrado)
Universidade de Coimbra, Portugal
2016 Functional investigation of OXPHOS assembly factors in Leber's Hereditary optic Neuropathy (LHON Maria Ine^s Are^lo Manso da Fonseca (Mestrado)
Universidade de Coimbra, Portugal
2016 Efeito da cirurgia baria´tica na func¸a~o endotelial associada a` diabetes tipo 2 Diana Cristina Miguel Ribeiro (Mestrado)
Universidade de Coimbra, Portugal
2016 Avaliac¸a~o dos mecanismos moleculares da resiste^ncia a hipometilantes em Leucemia Mieloide Aguda Patri´cia Isabel Martins Corredeira (Mestrado)
Universidade de Coimbra, Portugal
2016 Endothelial cell's response to proteostatic dysregulation: pursuing the protective action of ghrelin Daniela Alexandra Dinis Costa (Mestrado)
Universidade de Coimbra, Portugal
2016 The importance of cytokines-mediated communication in CSCs' formation Marco Rafael Lopes da Cunha (Mestrado)
Universidade de Coimbra, Portugal
2016 Modulatory effect of dietary pattern, exercise, and atorvastatin treatment on eNOS, sirtuins and miR-155 expression in the erectile tissue of the aged rat Ba´rbara Sofia Ferreira da Rocha (Mestrado)
Universidade do Porto, Portugal
2015/09/11 Effects of vitamin D deficient and high-fat diets in the diabetic brain: focus on insulin signaling Guilherme Alvarinhas de Assis Loureiro (Mestrado)
Universidade de Coimbra, Portugal
2015/07/14 Doxorubicin cardiotoxicity: Metabolic landscaping of the epigenome André de Melo Ferreira (Mestrado)
Universidade de Coimbra, Portugal
2015 Mitochondria-directed antioxidants as anticancer agents Katia Queirós Fernandes dos Santos (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2015 Effects of vitamin D deficient and high-fat diets in the diabetic brain: focus on insulin signaling
Arguente
Guilherme Alvarinhas de Assis Loureiro (Mestrado)
Universidade de Coimbra, Portugal
2015 Mitochondrial-directed antioxidants as anti-cancer agents Katia Queiro´s Fernandes dos Santos (Mestrado)
Universidade de Coimbra, Portugal
2015 Doxorubicin cardiotoxicity: Metabolic landscaping of the epigenome Andre´ de Melo Ferreira (Mestrado)
Universidade de Coimbra, Portugal
2015 Energia para a Regeneração Hepática:Bioenergética Mitocondrial e a Patogénese da Insuficiência Hepática Pós-Hepatectomia Henrique Miguel Marques Bom Borges Alexandrino (Doutoramento)
Universidade de Coimbra Faculdade de Medicina, Portugal

Comissão de avaliação

Descrição da atividade
Tipo de assessoria
Instituição / Organização Entidade financiadora
2019 - 2019 ''Research Projects'' Call
Avaliador
Hrvatska Zaklada za Znanost, Croácia
2017 - 2017 Grant proposal reviewer
Avaliador
Prinses Beatrix Spierfonds, Países Baixos
2017 - 2017 25o Concurso Jovens Cientistas e Investigadores - Mostra Nacional de Cie^ncia – Porto 2017
Avaliador
2016 - 2016 Cooperação Transnacional Hungria, Fundação para a Ciência e a Tecnologia
Avaliador
2016 - 2016 ''Research Projects'' Call
Avaliador
Hrvatska Zaklada za Znanost, Croácia
2015 - 2015 Concurso FCT de Bolsas individuais 2015 - PAINEL DE BIOMEDICINA E MEDICINA BÁSICA
Avaliador
Fundação para a Ciência e a Tecnologia, Portugal
2015 - 2015 Concurso FCT de Bolsas individuais 2015 - PAINEL DE BIOMEDICINA E MEDICINA BÁSICA - Audiências Prévias - 2015
Avaliador
Fundação para a Ciência e a Tecnologia, Portugal
2014 - 2014 Concurso FCT de Bolsas individuais 2014 - PAINEL DE BIOMEDICINA E MEDICINA BÁSICA
Avaliador
Fundação para a Ciência e a Tecnologia, Portugal
2014 - 2014 Concurso FCT de Bolsas individuais 2014 - PAINEL DE BIOMEDICINA E MEDICINA BÁSICA - Audiências Prévias
Avaliador
Fundação para a Ciência e a Tecnologia, Portugal

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2019 - Atual Fisiologia Celular (Licenciatura)
2015 - Atual Laboratórios de Biologia Molecular (Licenciatura)
2015 - Atual Toxicidade e Doença (Mestrado)
2015 - 2019 Fisiologia Humana (Licenciatura)

Entrevista (jornal / revista)

Descrição da atividade Jornal / Forum
2019 Entrevista - Mulheres e Ciência. Faces de Eva. Estudos sobre a Mulher Faces de Eva

Membro de associação

Nome da associação Tipo de participação
2018 - Atual Toxicology and Applied Pharmacology -corpo editorial
2014 - Atual Toxicology Mechanisms and Methods -corpo editorial Corpo editorial de publicação periódica
2012 - Atual European Association for the Study of Diabetes
2000 - Atual Sociedade Portuguesa de Bioquímica
Distinções

Outra distinção

2007 L’Oréal for Women in Science
1999 Premio Escolar Avelar Brotero
Universidade de Coimbra, Portugal
1998 Bolsa de Estudo por Merito
Universidade de Coimbra, Portugal
1997 Bolsa de Estudo por Merito
Universidade de Coimbra, Portugal