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Cruz Sebastião is an Angolan researcher at National Center for Scientific Research (CNIC), located in Luanda, the capital city of Angola, where he has been since 2025. He received his Ph.D. in Biomedicine from NMS|FCM of the Universidade Nova de Lisboa (UNL) in 2021, in Portugal. He participated as a postdoctoral fellow in the ENVOLVE Ciência PALOP program, funded by Calouste Gulbenkian Foundation (FCG), in Portugal, where he was part of the HIV/AIDS and Bioinformatics laboratory of the IHMT of the UNL in 2021, in Lisbon, Portugal. He has experience in HIV sequencing and phylogenetic analysis. He is able to prepare results for publication and write his own manuscripts. He has a very close collaboration with a public health research team in Portugal. He is also familiar with data analysis and statistics. He has more than 30 scientific publications in the fields of HIV/Sexually Transmitted Diseases, Arboviruses/Vector-borne Diseases and SARS-CoV-2/COVID-19, which have been published in international, peer-reviewed, impact-relevant scientific journals, such as, The Lancet Infectious Diseases, Scientific Reports, Journal of Medical Virology, PLOS ONE, Emerging Infectious Diseases, Tropical Medicine and Infectious Disease, Malaria Journal, AIDS Reviews, Health Science Reports, Journal of Infectious Diseases and Diagnosis, PLOS Neglected Tropical Diseases, and others. His current research project explores viral and host factors related to HIV-1 infection and molecular epidemiology of emerging infectious diseases (EID) in Angola. Also, he is working on optimizing and reducing the cost of HIV-1 drug resistance surveillance in Angola based on Next Generation Sequencing (Oxford Nanopore Technologies).
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Identificação

Identificação pessoal

Nome completo
Cruz dos Santos Sebastião

Nomes de citação

  • Cruz S. Sebastião
  • Cruz dos Santos Sebastião
  • Cruz Sebastião
  • Sebastião, CS
  • Sebastião, Cruz S.

Identificadores de autor

Ciência ID
831A-D545-A0CF
ORCID iD
0000-0003-1232-0119
Google Scholar ID
https://scholar.google.com/citations?user=zyaME38AAAAJ&hl=en
Scopus Author Id
57207938578

Endereços de correio eletrónico

  • cruz.sebastiao@nms.unl.pt (Profissional)
  • cruzdossantos10@gmail.com (Pessoal)

Telefones

Telemóvel
  • (+244) 937375617 (Pessoal)
  • (351) 936161739 (Pessoal)

Moradas

  • National Center for Scientific Research - CNIC, 0201-034, Avenida Ho Chi Minh, 201. CP34. Maianga, Luanda, Luanda, Angola (Profissional)

Domínios de atuação

  • Ciências Médicas e da Saúde

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Inglês Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1)
Formação
Grau Classificação
2017/10/01 - 2021/07/23
Concluído
 Biomedicina (associação) (Doutoramento)
Especialização em Sem especialidade
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
"HIV-1 infection among pregnant women in Angola: Molecular epidemiology and test of novel AZT triazole derivatives" (TESE/DISSERTAÇÃO)
2017/07/14
Concluído
 Ciências da Vida (Pós-Graduação)
Universidade de Cabo Verde, Cabo Verde

Universidade Jean Piaget de Cabo Verde, Cabo Verde

Instituto Gulbenkian de Ciência, Portugal
"Ciências da Vida" (TESE/DISSERTAÇÃO)
 60 ECTS
2012/02/01 - 2016/07/12
Concluído
 Análises Clínicas e Saúde Pública (Licenciatura)
Universidade Agostinho Neto, Angola
"Serum urea as an indicator of renal injury in patients hospitalized for malaria at Josina Machel - Maria Pia Hospital during the months of March to April 2016" (TESE/DISSERTAÇÃO)
 16/20
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2025/01/01 - Atual Investigador Auxiliar (carreira) (Investigação) National Center for Scientific Research - CNIC, Angola

Cargos e Funções

Categoria Profissional
Instituição de acolhimento 		Empregador
2021/11 - 2023/12/31 Coordenador Científico Centro de investigação em Saúde de Angola, Angola

Outros

Categoria Profissional
Instituição de acolhimento 		Empregador
2020/10/01 - 2024/12/31 Investigador Pós-Doutorado Centro de investigação em Saúde de Angola, Angola
2021/01/01 - 2024/11/15 Investigador Pós-Doutorado Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
Projetos

Bolsa

Designação Financiadores
2022/01/07 - 2023/09/30 A bioinformatics framework to understand the dissemination of viral EIDs in Angola
AREF-312-CRUZ-F-C0931
Investigador Pós-doutorado
Centro de investigação em Saúde de Angola, Angola

Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
African Research Excellence Fund
Em curso
2017/09/01 - 2021/07/23 HIV-1 infection among pregnant women in Angola: Molecular epidemiology and test of novel AZT triazole derivatives
SFRH/BD/135296/2017
Bolseiro de Doutoramento
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2017/09/01 - 2021/04/30 Base genética molecular do VIH-1 associado a resistênica aos anti-retrovirais nos pacientes em tratamento na província de Luanda. - Mutações de resistência primária em gestantes infectadas pelo VIH associado a transmissão vertical na maternidade Lucrécia Paím durante o segundo trimestre de 2018
SFRH/BD/135296/2017
Universidade NOVA de Lisboa NOVA Medical School, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído

Projeto

Designação Financiadores
2025/01/01 - 2026/01/31 GenoGuard: Applying low-cost next-generation sequencing for HIV-1 genomic surveillance and clinical care in pregnant women from Angola
GenoGuard
Investigador responsável
African Research Excellence Fund
Em curso
2022/01/01 - 2024/12/31 Next-generation sequencing to understand the HIV-1 transmission patterns in Angola
Nº.250466
Investigador responsável
Centro de investigação em Saúde de Angola, Angola
 Fundação Calouste Gulbenkian
Em curso
2022 - 2024 Diversidade genética e mutações de resistência antirretroviral em mulheres grávidas infectadas com o VIH em Angola
MESCTI/PDCT/2022
Investigador responsável
Em curso
2017/09/01 - 2021/04/30 Base genética molecular do VIH-1 associado a resistênica aos anti-retrovirais nos pacientes em tratamento na província de Luanda. - Mutações de resistência primária em gestantes infectadas pelo VIH associado a transmissão vertical na maternidade Lucrécia Paím durante o segundo trimestre de 2018
SFRH/BD/135296/2017
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
Produções

Publicações

Artigo em conferência
  1. Brito, Miguel; Ginete, Catarina; Ferreira, J.; Delgadinho, Mariana; Sebastião, Cruz; Mateus, A.; Mendes, M.; et al. "Preliminary findings from the follow-up of pregnant sickle cell disease patients in Luanda, Angola". 2023.
    10.1097/01.HS9.0000928520.27610.83
  2. Brito, Miguel; Ferreira, J.; Capriello, I.; Ginete, Catarina; Delgadinho, Mariana; Sebastião, Cruz; Mendes, M.; et al. "Genetic variability and disease severity in a cohort of Angolan sickle cell disease patients". 2022.
    10.1097/01.HS9.0000873120.65347.33
  3. Brito, Miguel; Ginete, Catarina; Ferreira, Joana; Mendes, Manuela; Vasconcelos, Jocelyne; Delgadinho, Mariana; Sebastião, Cruz; et al. "Pregnancy surveillance in sickle cell disease patients: a cohort study in an African country – Angola". 2022.
    10.1182/blood-2022-159681
  4. Brito, Miguel; Ginete, Catarina; Ferreira, Joana; Mendes, Manuela; Vasconcelos, Jocelyne; Delgadinho, Mariana; Sebastião, Cruz; et al. "Pregnancy surveillance in sickle cell disease patients: a cohort study in an African country – Angola". 2022.
    10.1182/blood-2022-159681
Artigo em revista
  1. Abrantes, Ricardo; Pimentel, Victor; Sebastião, Cruz; Miranda, Mafalda N.S.; Seabra, Sofia; Silva, Ana Rita; Diniz, António; et al. "Determinants of HIV-1 transmission clusters and transmitted drug resistance in men who have sex with men: A multicenter study in Portugal (2014-2019)". International Journal of Infectious Diseases 155 (2025): 107888. https://doi.org/10.1016/j.ijid.2025.107888.
    10.1016/j.ijid.2025.107888
  2. Gonçalves, Fátima; Cabanas, Joaquim; Costa, Inês; Veloso, Margarida; Ribeiro, Marta; Fernandes, Sandra; Diogo, Isabel; et al. "Hybrid next-generation sequencing protocol for testing HIV-2 drug resistance". Journal of Virological Methods 334 (2025): 115112. https://doi.org/10.1016/j.jviromet.2025.115112.
    10.1016/j.jviromet.2025.115112
  3. Cruz S. Sebastião; Domingos Jandondo; João Vigário; Felícia António; Joana M. K. Sebastião; Maria L. S. Silva; Victor Pimentel; et al. "Seroprevalence and Risk Factors of STIs among Rejected Blood Donors at the National Blood Transfusion Service in Angola". AIDS and Behavior (2025): https://doi.org/10.1007/s10461-025-04700-3.
    10.1007/s10461-025-04700-3
  4. Elias José Gonçalves; Crícia do Espírito Santo Nunda; Cruz dos Santos Sebastião; Margarete Lopes Teixeira Arrais. "Prevalence of Asthma, Allergic Rhinitis, and Eczema in Schoolchildren From Huambo, Angola: A Cross-Sectional Study". Health Science Reports (2025): https://doi.org/10.1002/hsr2.70678.
    10.1002/hsr2.70678
  5. Cruz S. Sebastião; Jamila Bathy; Tacilta Nhampossa; André Santos; Mafalda Miranda; Neusa Magode Manhiça; Rubão Bila; et al. "Susceptibility to Lenacapavir Among Newly Diagnosed HIV-Positive Patients Followed Up in Mozambique That Presented With Primary Antiretroviral Resistance to Other Classes". Journal of Medical Virology (2025): https://doi.org/10.1002/jmv.70317.
    10.1002/jmv.70317
  6. Almeida, Pedro R.S.; Rafael, Carlos A.C.; Pimentel, Victor; Abecasis, Ana B.; Sebastião, Cruz S.; de Morais, Joana. "Adherence to antiretroviral therapy among HIV-1 patients from sub-Saharan Africa: a systematic review". Aids Reviews 26 3 (2024): http://dx.doi.org/10.24875/aidsrev.24000004.
    10.24875/aidsrev.24000004
  7. Sebastião, Cruz S.; Pingarilho, Marta; Bathy, Jamila; Bonfim, Elizângela; Toancha, Katia; Miranda, Mafalda N.S.; Martins, M Rosário O.; et al. "MARVEL-minimising the emergence and dissemination of HIV-1 drug resistance in Portuguese-speaking African Countries (PALOP): low-cost portable NGS platform for HIV-1 surveillance in Africa". BMC Infectious Diseases 24 1 (2024): http://dx.doi.org/10.1186/s12879-024-09803-1.
    10.1186/s12879-024-09803-1
  8. Jandondo, Domingos; Pimentel, Victor; Vigário, João; Vienga, Pedro; Sebastião, Joana M. K.; Mateus, Anabela; Comandante, Felícia; et al. "Sociodemographic and clinical features related to hepatitis B virus infection among rejected blood donors in Luanda, Angola". Health Science Reports 7 8 (2024): http://dx.doi.org/10.1002/hsr2.2287.
    10.1002/hsr2.2287
  9. Sebastião, Cruz S.; Abecasis, Ana B.; Jandondo, Domingos; Sebastião, Joana M. K.; Vigário, João; Comandante, Felícia; Pingarilho, Marta; et al. "HIV-1 diversity and pre-treatment drug resistance in the era of integrase inhibitor among newly diagnosed ART-naïve adult patients in Luanda, Angola". Scientific Reports 14 1 (2024): http://dx.doi.org/10.1038/s41598-024-66905-1.
    10.1038/s41598-024-66905-1
  10. Mafalda N. S. Miranda; Victor Pimentel; Jacqueline Graça; Sofia G. Seabra; Cruz S. Sebastião; António Diniz; Domitília Faria; et al. "Sociodemographic, Clinical, and Behavioral Factors Associated with Sexual Transmitted Infection among HIV-1 Positive Migrants in Portugal: Are There Differences between Sexes?". Pathogens (2024): https://www.mdpi.com/2076-0817/13/7/598.
    10.3390/pathogens13070598
  11. Pimentel, Victor; Pineda-Peña, Andrea; Sebastião, Cruz S.; de Paula, João L.; Ahagon, Cintia M.; Pingarilho, Marta; Martins, M. Rosário O.; et al. "Dynamics and features of transmission clusters of HIV-1 subtypes in the state of São Paulo, Brazil". Frontiers in Public Health 12 (2024): http://dx.doi.org/10.3389/fpubh.2024.1384512.
    10.3389/fpubh.2024.1384512
  12. Pimentel, Victor; Pingarilho, Marta; Sebastião, Cruz S.; Miranda, Mafalda; Gonçalves, Fátima; Cabanas, Joaquim; Costa, Inês; et al. "Applying Next-Generation Sequencing to Track HIV-1 Drug Resistance Mutations Circulating in Portugal". Viruses 16 4 (2024): 622. http://dx.doi.org/10.3390/v16040622.
    10.3390/v16040622
  13. Cruz S. Sebastião; Euclides Sacomboio; Ngiambudulu M. Francisco; Edson K. Cassinela; António Mateus; Zinga David; Victor Pimentel; et al. "Blood pressure pattern among blood donors exposed to SARS-CoV-2 in Luanda, Angola: A retrospective study". Health Science Reports (2023): https://doi.org/10.1002/hsr2.1498.
    10.1002/hsr2.1498
  14. Cruz S. Sebastião; Euclides Sacomboio; Ngiambudulu M. Francisco; Joana Paixão; Edson K. Cassinela; Jocelyne Neto de Vasconcelos; Victor Pimentel; Joana Morais. "Demographic characteristics and risk factors related to high blood pressure among healthy blood donors from Luanda, Angola: A retrospective study". Health Science Reports (2023): https://doi.org/10.1002/hsr2.1300.
    10.1002/hsr2.1300
  15. Cruz S. Sebastião; Euclides Sacomboio; Ngiambudulu M. Francisco; Edson K. Cassinela; António Mateus; Zinga David; Joana Paixão; Jocelyne Neto de Vasconcelos; Joana Morais. "Immune profile of healthcare professionals six months after vaccination or exposure to SARS-CoV-2 in Angola". Health Science Reports (2023): https://doi.org/10.1002/hsr2.1058.
    10.1002/hsr2.1058
  16. Dias, W.; Silva, M.; Sebastião, C.S.; Arrais, M.. "A study of persistent symptoms and pulmonary function at 3 months post moderate or severe COVID-19 in Angola". The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 27 3 (2023): 229-231. http://www.scopus.com/inward/record.url?eid=2-s2.0-85149152941&partnerID=MN8TOARS.
    10.5588/ijtld.22.0494
  17. Paulo Nunes, Ema; da Costa, Maurício; Kuatelela Cassinela, Edson; dos Santos Sebastião, Cruz; Manuel Sacomboio, Euclides Nenga. "Fatores associados a hemorragia pós parto em parturientes atendidas no Hospital Geral Especializado Kilamba Kiaxi". (2023): https://doi.org/10.51126/revsalus.v5iSup.536.
    https://doi.org/10.51126/revsalus.v5iSup.536
  18. Sebastião, Cruz S.; Sacomboio, Euclides; Francisco, Ngiambudulu M.; Paixão, Joana; Cassinela, Edson K.; de Vasconcelos, Jocelyne Neto; Pimentel, Victor; Morais, Joana. "Demographic characteristics and risk factors related to high blood pressure among healthy blood donors from Luanda, Angola". (2023): http://hdl.handle.net/10362/155236.
    https://doi.org/10.1002/hsr2.1300
  19. Berta David, Catarina; da Costa, Maurício; dos Santos Sebastião, Cruz; Manuel Sacomboio, Euclides Nenga. "Características comuns de grávidas com hipertensão atendidas na sala de parto do Hospital Geral de Luanda". (2023): https://doi.org/10.51126/revsalus.v5iSup.535.
    https://doi.org/10.51126/revsalus.v5iSup.535
  20. Sebastião, Cruz S.; Sacomboio, Euclides; Francisco, Ngiambudulu M.; Paixão, Joana; Cassinela, Edson K.; de Vasconcelos, Jocelyne Neto; Pimentel, Victor; Morais, Joana. "Demographic characteristics and risk factors related to high blood pressure among healthy blood donors from Luanda, Angola". (2023): http://hdl.handle.net/10362/155236.
    https://doi.org/10.1002/hsr2.1300
  21. Cruz S. Sebastião; Adis Cogle; Alice D’Alva Teixeira; Ana Micolo Cândido; Chissengo Tchoni; Maria João Amorim; N’gueza Loureiro; et al. "Clinical Features Related to Severity and Mortality among COVID-19 Patients in a Pre-Vaccine Period in Luanda, Angola". Tropical Medicine and Infectious Disease (2022): https://doi.org/10.3390/tropicalmed7110338.
    10.3390/tropicalmed7110338
  22. Zoraima Neto; David W.C. Beasley; Pedro A. Martinez; Sarah C. Hill; Domingos Jandondo; Julien Thézé; Marinela Mirandela; et al. "Molecular and genomic investigation of an urban outbreak of dengue virus serotype 2 in Angola, 2017–2019". PLOS Neglected Tropical Diseases 16 5 (2022): e0010255-e0010255. https://doi.org/10.1371/journal.pntd.0010255.
    10.1371/journal.pntd.0010255
  23. Sebastião CS; Samulengo J; Sacomboio E; Francisco NM; Teixeira C; António S; Kinanga M; et al. "Epidemiological Characteristics and Risk Factors Related to Drug-resistant Tuberculosis in Luanda, Angola.". The American journal of tropical medicine and hygiene (2022): http://europepmc.org/abstract/med/35008058.
    10.4269/ajtmh.21-0659
  24. Paixao, J.; Galangue, M.; Gaston, C.; Carralero, R.; Lino, C.; Júlio, G.; David, Z.; et al. "Early Evidence of Circulating SARS-CoV-2 in Unvaccinated and Vaccinated Measles Patients, September 2019–February 2020". Infection and Drug Resistance 15 (2022): 533-544. http://www.scopus.com/inward/record.url?eid=2-s2.0-85125075462&partnerID=MN8TOARS.
    10.2147/IDR.S344437
  25. Sebastião, C.S.; Neto, Z.; Jandondo, D.; Mirandela, M.; Morais, J.; Brito, M.; Sebastião, Cruz S.; et al. "Dengue virus among HIV-infected pregnant women attending antenatal care in Luanda, Angola: An emerging public health concern". Scientific African 17 (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85137753803&partnerID=MN8TOARS.
    10.1016/j.sciaf.2022.e01356
  26. Sacomboio, E.N.M.; Dos Santos Sebastião, C.; Salvador, S.T.D.C.; João, J.A.; Bapolo, D.V.S.; Francisco, N.M.; Morais, J.; Valentim, E.E.. "Evaluation of blood cell count parameters as predictors of treatment failure of malaria in Angola: An observational study". PloS one 17 5 (2022): e0267671-e0267671. http://www.scopus.com/inward/record.url?eid=2-s2.0-85129997491&partnerID=MN8TOARS.
    10.1371/journal.pone.0267671
  27. Sebastião, Cruz S.; Cogle, Adis; Teixeira, Alice D’Alva; Cândido, Ana Micolo; Tchoni, Chissengo; Amorim, Maria João; Loureiro, N’gueza; et al. "Clinical features related to severity and mortality among COVID-19 patients in a pre-vaccine period in Luanda, Angola". (2022): http://hdl.handle.net/10400.14/39442.
    10.3390/tropicalmed7110338
  28. Sebastião, Cruz S.; Cogle, Adis; Teixeira, Alice D’Alva; Cândido, Ana Micolo; Tchoni, Chissengo; Amorim, Maria João; Loureiro, N’gueza; et al. "Clinical features related to severity and mortality among COVID-19 patients in a pre-vaccine period in Luanda, Angola". (2022): http://hdl.handle.net/10400.21/15132.
    10.3390/tropicalmed7110338
  29. Cruz S. Sebastião; Paolo Parimbelli; Manuela Mendes; Euclides Sacomboio; Joana Morais; Jocelyne Neto de Vasconcelos; Miguel Brito. "Prevalence and Risk Factors of SARS-CoV-2 Infection among Parturients and Newborns from Luanda, Angola". Pathogens 10 11 (2021): 1494-1494. https://doi.org/10.3390/pathogens10111494.
    10.3390/pathogens10111494
  30. Daniel Machado de Alencar; Juliana Gonçalves; Andreia Vieira; Sofia A. Cerqueira; Cruz Sebastião; Maria Inês P. S. Leitão; Giulia Francescato; et al. "Development of Triazoles and Triazolium Salts Based on AZT and Their Anti-Viral Activity against HIV-1". Molecules (2021): https://doi.org/10.3390/molecules26216720.
    10.3390/molecules26216720
  31. Cruz S. Sebastião; Celestina Gaston; Joana Paula Paixão; Euclides N. M. Sacomboio; Zoraima Neto; Jocelyne Neto Vasconcelos; Joana Morais. "Coinfection between SARS-CoV-2 and vector-borne diseases in Luanda, Angola". Journal of Medical Virology (2021): https://doi.org/10.1002/jmv.27354.
    10.1002/jmv.27354
  32. Cruz S. Sebastião; Manuela Galangue; Celestina Gaston; Rui Van-Dunen; Domingos Jandondo; Zoraima Neto; Jocelyne Neto de Vasconcelos; Joana Morais. "Serological identification of past and recent SARS-CoV -2 infection through antibody screening in Luanda, Angola". Health Science Reports 4 2 (2021): https://doi.org/10.1002/hsr2.280.
    10.1002/hsr2.280
  33. Cruz S. Sebastião; Muhammad Adrish; Zoraima Neto; Pedro Martinez; Domingos Jandondo; Janete Antonio; Manuela Galangue; et al. "Sociodemographic characteristics and risk factors related to SARS-CoV-2 infection in Luanda, Angola". PLOS ONE (2021): https://doi.org/10.1371/journal.pone.0249249.
    10.1371/journal.pone.0249249
  34. Cruz Sebastião; Joana Morais; Miguel Brito. "Factors Influencing HIV Drug Resistance among Pregnant Women in Luanda, Angola: Findings from a Cross-Sectional Study". Tropical Medicine and Infectious Disease (2021): https://www.mdpi.com/2414-6366/6/1/29.
    10.3390/tropicalmed6010029
  35. Sebastião, C.S.; Neto, Z.; Martinez, P.; Jandondo, D.; Antonio, J.; Galangue, M.; de Carvalho, M.; et al. "Erratum: Sociodemographic characteristics and risk factors related to SARS-CoV-2 infection in Luanda, Angola (PLoS ONE (2021) 16:3 (e0249249) DOI: 10.1371/journal.pone.0249249)". PLoS ONE 16 5 May (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85106593583&partnerID=MN8TOARS.
    10.1371/journal.pone.0252254
  36. Sebastião, C.S.; Galangue, M.; Gaston, C.; Van-Dunen, R.; Quivinja, J.; Lunbungululo, E.; Alfredo, D.; et al. "Seroprevalence of anti-SARS-CoV-2 antibodies and risk factors among healthy blood donors in Luanda, Angola". BMC Infectious Diseases 21 1 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85118722050&partnerID=MN8TOARS.
    10.1186/s12879-021-06814-0
  37. Sebastião, Cruz S.; Morais, Joana; Brito, Miguel. "Factors influencing HIV drug resistance among pregnant women in Luanda, Angola: findings from a cross-sectional study". (2021): http://hdl.handle.net/10400.21/13048.
    10.3390/tropicalmed6010029
  38. Sebastião, Cruz S.; Morais, Joana; Brito, Miguel. "Clinical and public health implications of HIV-genetic diversity and drug resistance mutations in Angola: a systematic review". (2021): http://hdl.handle.net/10400.21/12423.
    10.24875/AIDSRev.20000057
  39. Sebastião, Cruz S.; Parimbelli, Paolo; Mendes, Manuela; Sacomboio, Euclides; Morais, Joana; Vasconcelos, Jocelyne Neto de; Brito, Miguel. "Prevalence and risk factors of SARS-CoV-2 infection among parturients and newborns from Luanda, Angola". (2021): http://hdl.handle.net/10400.21/14103.
    10.3390/pathogens10111494
  40. Sebastião, Cruz S.; Neto, Zoraima; Jandondo, Domingos; Mirandela, Marinela; Morais, Joana; Brito, Miguel. "HIV, hepatitis B virus, hepatitis C virus, and syphilis among pregnant women attending antenatal care in Luanda, Angola: Seroprevalence and risk factors". Journal of Medical Virology (2020): http://dx.doi.org/10.1002/jmv.26148.
    Publicado • 10.1002/jmv.26148
  41. Sebastião, C.S.; Morais, J.; Brito, M.. "Clinical and public health implications of hiv-1 genetic diversity and drug resistance mutations in angola: A systematic review". AIDS Reviews 22 4 (2020): 1-9. http://www.scopus.com/inward/record.url?eid=2-s2.0-85098685362&partnerID=MN8TOARS.
    10.24875/AIDSRev.20000057
  42. Sacomboio, Euclides Nenga Manuel; Santos Sebastião, Cruz dos; Tchivango, Adelino Tchilanda; Pecoits-Filho, Roberto; Calice-Silva, Viviane. "Does parasitemia level increase the risk of acute kidney injury in patients with malaria? Results from an observational study in Angola". Scientific African 7 (2019): e00232. http://dx.doi.org/10.1016/j.sciaf.2019.e00232.
    Publicado • 10.1016/j.sciaf.2019.e00232
  43. Hill, Sarah C; Vasconcelos, Jocelyne; Neto, Zoraima; Jandondo, Domingos; Zé-Zé, Líbia; Aguiar, Renato Santana; Xavier, Joilson; et al. "Emergence of the Asian lineage of Zika virus in Angola: an outbreak investigation". The Lancet Infectious Diseases 19 10 (2019): 1138-1147. http://dx.doi.org/10.1016/s1473-3099(19)30293-2.
    Publicado • 10.1016/s1473-3099(19)30293-2
  44. Hill, Sarah C.; Neto de Vasconcelos, Jocelyne; Granja, Bernardo Gutierrez; Thézé, Julien; Jandondo, Domingos; Neto, Zoraima; Mirandela, Marinela; et al. "Early Genomic Detection of Cosmopolitan Genotype of Dengue Virus Serotype 2, Angola, 2018". Emerging Infectious Diseases 25 4 (2019): 784-787. http://dx.doi.org/10.3201/eid2504.180958.
    Publicado • 10.3201/eid2504.180958
  45. Cruz S. Sebastião; Neto, Zoraima; Jesus, Carlos S. de; Mirandela, Marinela; Jandondo, Domingos; Couto-Fernandez, José C.; Tanuri, Amilcar; Morais, Joana; Brito, Miguel. "Genetic diversity and drug resistance of HIV-1 among infected pregnant women newly diagnosed in Luanda, Angola". PLoS ONE (2019): http://hdl.handle.net/10400.21/10757.
    Publicado • 10.1371/journal.pone.0225251
  46. Calice-Silva, Viviane; Sacomboio, Euclides; Raimann, Jochen G.; Evans, Rhys; dos Santos Sebastião, Cruz; Tchivango, Adelino Tchilanda; Kotanko, Peter; Levin, Nathan; Pecoits-Filho, Roberto. "Diagnostic performance of salivary urea nitrogen dipstick to detect and monitor acute kidney disease in patients with malaria". Malaria Journal 17 1 (2018): http://dx.doi.org/10.1186/s12936-018-2627-4.
    Publicado • 10.1186/s12936-018-2627-4
Poster em conferência
  1. Cruz S. Sebastião; Gomes P.; et al.. "Prevalência da resistência ao lenacapavir em indivíduos recém-diagnosticados com vih-1 em moçambique.". Trabalho apresentado em XVI Congresso Nacional de Doenças Infeciosas e Microbiologia Clínica | XIV Congresso Nacional VIH/SIDA, 27 a 30 de novembro de 2024., 2024.
  2. Cruz S. Sebastião; Abecasis, Ana; Gomes P.; et al. "Portable Next-Generation Sequencing Reveals No Transmitted Drug Resistance to Integrase Inhibitors and HIV-1C Clustering among Newly Diagnosed in Angola.". Trabalho apresentado em European Meeting on HIV & Hepatitis 2024 | Treatment Strategies & Antiviral Drug Resistance Barcelona, Spain | 22 - 24 May 2024, 2024.
  3. Pimentel, Victor; Pingarilho, Marta; Cruz Sebastião; Mafalda Miranda; Seabra, Sofia; GOMES, Perpetua; Abecasis, Ana. "Traansmissão do subtipo A de VIH-1 em Portugal: Aborgagens genéticas, clínicas e epidemiológicas.". Trabalho apresentado em 14ªs Jornadas de Atualização de Doenças Infeciosas do Hospital Curry Cabral (CHLC), 25 e 26 janeiro de 2024, 2024.
  4. Pimentel, Victor; Pingarilho, Marta; Cruz Sebastião; Mafalda Miranda; Seabra, Sofia; GOMES, Perpetua; Abecasis, Ana. "Transmissão do subtipo A de VIH-1 em Portugal: Aborgagens genéticas, clínicas e epidemiológicas.". Trabalho apresentado em 14ªs Jornadas de Atualização de Doenças Infeciosas do Hospital Curry Cabral (CHLC), 25 e 26 janeiro de 2024, 2024.
  5. Pimentel, Victor; Pingarilho, Marta; Cruz Sebastião; Barbosa, Ana Mafalda Castanheira Neves de Miranda; Seabra S.; Fatima Gonçalves; Fernandes, Sandra; et al. Autor correspondente: Pimentel, Victor. "Low Prevalence of Resistance Mutations Associated With Integrase Inhibitors as Detected by Sanger and Next Generation Sequencing Among HIV-1 Patients Followed Up in Portugal.". Trabalho apresentado em 21st European Meeting on HIV & Hepatitis. 7-9 June 2023. Rome. Italy., 2023.
  6. Brito, Miguel; Joana Alexandra Gomes Ferreira; Ginete, Catarina; Delgadinho, Mariana; Cruz Sebastião; Manuela Mendes; Francisco Quintino; et al. "Sickle cell disease in Angola. A public health problem. Genetic variability and disease severity in a cohort of pregnant women". Trabalho apresentado em Annual Meeting of the American Society of Tropical Medicine and Hygiene (ASTMH), 2022.
Pré-impressão
  1. Euclides Sacomboio; Cruz Sebastião. "Biological and social characteristics related to parasitemia in patients with malaria in Luanda-Angola". 2024. https://doi.org/10.31124/advance.172249630.04995849/v1.
    10.31124/advance.172249630.04995849/v1
  2. Pedro RS Almeida; Victor Pimentel; Ana Abecasis; Cruz S. Sebastião; Joana Morais. "Demographic and behavioural determinants related to ART adherence among HIV-positive patients in Luanda, Angola". 2024. https://doi.org/10.21203/rs.3.rs-4312271/v1.
    10.21203/rs.3.rs-4312271/v1
  3. Sebastião, Cruz; Cassinela, Edson; Manuel, Vilma; Matary, Wilma; Nkuku, Maria; Piedade, Isabel; Filipe, Cátia; Cristóvão, Lourenço; Sacomboio, Euclides. "Dynamics of Liver Function among Patients with Malaria in Luanda, Angola: A Cross-Sectional Study". 2024. http://dx.doi.org/10.20944/preprints202408.0224.v1.
    10.20944/preprints202408.0224.v1
  4. Cruz Sebastião; Carlos Rafael; Victor Pimentel; Ana Abecasis; Joana Morais. "Adherence to Antiretroviral Therapy (ART) Among HIV-1 Patients From Sub-Saharan Africa: A Systematic Review". 2024. https://doi.org/10.20944/preprints202404.1615.v1.
    10.20944/preprints202404.1615.v1
  5. Cruz Sebastião; Victor Pimentel; Domingos Jandondo; António Vigário; Pedro Vienga; Joana Sebastião; Anabela Mateus; et al. "Sociodemographic and clinical features related to hepatitis B virus infection among rejected blood donors in Luanda, Angola". 2023. https://doi.org/10.22541/au.167889284.46430988/v1.
    10.22541/au.167889284.46430988/v1
  6. NGIAMBUDULU M. FRANCISCO; Stephanie Van Wyk; Monika Moir; James San; Cruz Sebastiao; Houriiyah Tegally; Joicymara Xavier; et al. "Insights into SARS-CoV-2 in Angola during the COVID-19 Peak: Molecular Epidemiology and Genome Surveillance". 2023. https://doi.org/10.22541/au.168733266.66797147/v1.
    10.22541/au.168733266.66797147/v1
  7. Job Pakisi; Cruz Sebastião; Jocelyne Vasconcelos; Leticia Valdeón; Enrique Darkistad. "Sociodemographic Characteristics and Risk Factors Related to Hypertension among Individuals from Huambo, Angola". 2023. https://doi.org/10.20944/preprints202310.2037.v1.
    10.20944/preprints202310.2037.v1
  8. Edson Kutelela Cassinela; Lourenço Quixari; Silvana da Rocha Silveira; Cruz dos Santos Sebastião; António Armando; Carlos Pinto-Sousa; José Fernando; Manuel Sangombe Epalanga; Euclides Nenga Manuel Sacomboio. "Cancer Screening in Angolan Individuals Using Tumor Marker Tests at Mediag, Luanda-Angola". 2023. https://doi.org/10.20944/preprints202312.0168.v1.
    10.20944/preprints202312.0168.v1
  9. Euclides Nenga Manuel Sacomboio; Telma Patrícia Pereira Paulo; Edson Kuatelela Cassinela; Cruz dos Santos Sebastião. "Urinalysis Results and Resistance to Hospital Treatment with Injectable Antimalarials in Angola". 2023. https://doi.org/10.20944/preprints202312.0167.v1.
    10.20944/preprints202312.0167.v1
  10. Domingos Jandondo; Kuta Luís; Euclides Sacomboio; Joana Morais; Cruz S. Sebastião. "Sociodemographic characteristics and risk factors related to DENV infection among individuals from Luanda, Angola". 2023. https://doi.org/10.21203/rs.3.rs-3373183/v1.
    10.21203/rs.3.rs-3373183/v1
  11. Euclides Nenga Manuel Sacomboio; Tomásia Oliveira Muhongo; Adelino Tchilanda Tchivango; Edson Kuatelela Cassinela; Silvana da Rocha Silveira; Mauricio Da Costa; Carlos Alberto Pinto de Sousa; Cruz Sebastião Sebastião; Eduardo Ekundi Valentim. "Blood Groups (ABO/Rh) And Sociodemographic and Clinical Profile among Patients with Leprosy in Angola". 2022. https://doi.org/10.20944/preprints202209.0299.v1.
    10.20944/preprints202209.0299.v1
  12. Cruz S. Sebastião; Alice Teixeira; Ana Luísa; Margarete Arrais; Chissengo Tchonhi; Adis Cogle; Euclides Sacomboio; et al. "The impact of the ABO/Rh blood group on susceptibility and severity among COVID-19 patients in Luanda, Angola". 2022. https://doi.org/10.1101/2022.10.14.512325.
    10.1101/2022.10.14.512325
  13. Cruz S. Sebastião; João Samulengo; Joana Pauxão; António Mateus; Zinga David; Jocelyne Neto De Vasconcelos; Joana Morais. "Risk Factors Related to HIV Infection among TB Patients in Luanda, Angola". 2022. https://doi.org/10.20944/preprints202211.0022.v1.
    10.20944/preprints202211.0022.v1
  14. Cruz Sebastião; Euclides Sacomboio; Ngiambudulu Francisco; Joana Paixão; Edson Cassinela; Jocelyne Neto de Vasconcelos; Victor Pimentel; Joana Morais. "Demographic characteristics and risk factors related to high blood pressure among healthy blood donors from Luanda, Angola". 2022. https://doi.org/10.21203/rs.3.rs-2121605/v1.
    10.21203/rs.3.rs-2121605/v1
Tese / Dissertação
  1. Sebastião, Cruz dos Santos. "HIV-1 Infection Among Pregnant Women In Angola: Molecular Epidemiology and Test of Novel Azt Triazole Derivatives". Doutoramento, 2021. http://hdl.handle.net/10362/124097.

Outros

Outra produção
  1. Frequency of Abo/rh Blood Groups Among Patients With Diabetes Mellitus in Luanda, Angola. 2022. Sacomboio, E.N.M.; Pululo, S.A.; Sebastião, C.S.; Tchivango, A.T.; da Rocha Silveira, S.; da Costa, M.; Sousa, C.A.P.; Ekundi-Valentim, E.; Cassinela, E.K.. http://www.scopus.com/inward/record.url?eid=2-s2.0-85146504277&partnerID=MN8TOARS.
    10.21203/rs.3.rs-2269234
  2. Demographic characteristics and risk factors related to high blood pressure among healthy blood donors from Luanda, Angola. 2022. Sebastião, C.; Sacomboio, E.; Francisco, N.; Paixão, J.; Cassinela, E.; de Vasconcelos, J.N.; Pimentel, V.; Morais, J.. http://www.scopus.com/inward/record.url?eid=2-s2.0-85146413759&partnerID=MN8TOARS.
    10.21203/rs.3.rs-2121605
  3. Blood pressure pattern among blood donors exposed to SARS-CoV-2 in Luanda, Angola. 2022. Sebastião, C.S.; Sacomboio, E.; Francisco, N.M.; Cassinela, E.K.; Mateus, A.; David, Z.; Pimentel, V.; et al. http://www.scopus.com/inward/record.url?eid=2-s2.0-85142244443&partnerID=MN8TOARS.
    10.21203/rs.3.rs-2121706
  4. Emergence of the Zika virus Asian lineage in Angola. 2019. Hill, S.C.; Vasconcelos, J.; Neto, Z.; Jandondo, D.; Zé-Zé, L.; Aguiar, R.S.; Xavier, J.; et al. http://www.scopus.com/inward/record.url?eid=2-s2.0-85095621899&partnerID=MN8TOARS.
    10.1101/520437
  5. Early genomic detection of the Cosmopolitan Genotype of Dengue Virus 2 in Angola, 2018. 2018. Hill, S.C.; Vasconcelos de, J.N.; Granja, B.G.; Thézé, J.; Jandondo, D.; Neto, Z.; Mirandela, M.; et al. http://www.scopus.com/inward/record.url?eid=2-s2.0-85095533457&partnerID=MN8TOARS.
    10.1101/424747
Atividades

Orientação

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2018 - 2018 Capillary glycemia levels in residents of Bula-Atumba-Bengo, January 2018.
Orientador
 Análises Clínicas e Saúde Pública (Licenciatura/Bacharelato)
Universidade Agostinho Neto, Angola
2018 - 2018 Capillary glycemia levels in residents of the Rocha Pinto neighborhood evaluated in the month of March 2018.
Coorientador
 Análises Clínicas e Saúde Pública (Licenciatura/Bacharelato)
Universidade Agostinho Neto, Angola
2018 - 2018 Prevalence of heavy drop malaria in residents of the Rocha Pinto Quarter evaluated at our Lady of Peace church during the month of March 2018.
Orientador
 Análises Clínicas e Saúde Pública (Licenciatura/Bacharelato)
Universidade Agostinho Neto, Angola
2018 - 2018 Prevalence of syphilis in pregnant women newly diagnosed with HIV at Lucrécia Paim Maternity during the second trimester of 2018.
Orientador
 Análises Clínicas e Saúde Pública (Licenciatura/Bacharelato)
Universidade Agostinho Neto, Angola
2018 - 2018 Prevalence of tuberculosis in pregnant women newly diagnosed with HIV at Lucrécia Paim Maternity Hospital during the 2nd trimester of 2018.
Orientador
 Análises Clínicas e Saúde Pública (Licenciatura/Bacharelato)
Universidade Agostinho Neto, Angola
2018 - 2018 Prevalence of hepatitis B in pregnant women newly diagnosed with HIV at Lucrécia Paim Maternity during the second trimester of 2018.
Orientador
 Análises Clínicas e Saúde Pública (Licenciatura/Bacharelato)
Universidade Agostinho Neto, Angola
2018 - 2018 Prevalence of hepatitis C in pregnant women newly diagnosed with HIV at Lucrécia Paim Maternity during the second trimester of 2018.
Orientador
 Análises Clínicas e Saúde Pública (Licenciatura/Bacharelato)
Universidade Agostinho Neto, Angola
2018 - 2018 HIV prevalence in pregnant women at Lucrécia Paim Maternity during the second trimester of 2018.
Orientador
 Análises Clínicas e Saúde Pública (Licenciatura/Bacharelato)
Universidade Agostinho Neto, Angola

Participação em evento

Descrição da atividade
Tipo de evento 		Nome do evento
Instituição / Organização
2019 - Atual Third National Congress of Laboratory Biomedical Sciences.
Congresso
 Third National Congress of Laboratory Biomedical Sciences.
2018 - Atual 10th Scientific Days of the Higher Institute of Health Sciences of the Agostinho Neto University.
Congresso
 10th Scientific Days of the Higher Institute of Health Sciences of the Agostinho Neto University.
Universidade Agostinho Neto, Angola
2017 - Atual Second National Congress of Laboratory Biomedical Sciences.
Congresso
 Second National Congress of Laboratory Biomedical Sciences.
Distinções

Outra distinção

2016 Elected the best student of the Clinical Analysis and Public Health course in the year 2016.
Universidade Agostinho Neto, Angola