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Maria João Bessa graduated in Bioengineering from the Faculty of Engineering and Institute of Biomedical Sciences Abel Salazar (ICBAS) of the University of Porto (UP) in 2015. She recently earned her PhD in Biomedical Sciences from ICBAS-UP in July 2022. Maria João has a strong background in health-related scientific research, mainly focusing on the in vitro toxicity assessment of (nano)particles and chemicals emitted during real scenarios of occupational exposure. During her PhD, she evaluated the toxicity of nanoparticles used in the manufacturing of ceramic goods or released from industrial processes employed in the ceramic industry, using both conventional (2D) and advanced (3D) in vitro pulmonary cell models (CERASAFE project - SIINN/0004/2014). Currently, Maria João is a Post-Doc Research Fellow in the 4FirHealth funded project (PCIF/SSO/0090/2019) aimed at investigating firefighters' occupational exposure to health-relevant pollutants released during fires, with a focus on dermal, inhalation and ingestion routes, using 2D and 3D in vitro cell models. Until now, Maria João has participated in 7 national and international research projects, publishing 21 peer-reviewed scientific papers (9 as the first author) and 2 book chapters. Over the years, she has strengthened her technical and scientific skills in the field of in vitro toxicology and health-related sciences by participating in many international training courses, most of which she was awarded with travel grants and fellowship support. Maria João also shared her work with the scientific community in different national and international congresses of reference in the field of Toxicology and Nanosciences, including 10 oral (6 as the main speaker) and 20 poster communications, and 6 conference proceedings. Maria João was also involved in seminars and training classes for MSc and PhD students in the medical health area and in the follow-up and monitoring of young scientists. Throughout her career, Maria João has gained important technical expertise, scientific maturity, mentoring abilities, and other crucial skills including research methodology, critical thinking, communication, teamwork collaboration, time management, adaptability, and resilience, which highly contributed to her growth as an independent scientist.
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Identificação

Identificação pessoal

Nome completo
Maria João Bessa

Nomes de citação

  • Bessa, Maria João
  • Bessa, M.J.

Identificadores de autor

Ciência ID
7710-8F47-7A48
ORCID iD
0000-0001-5357-6167

Websites

Domínios de atuação

  • Ciências Médicas e da Saúde - Medicina Básica - Toxicologia
  • Ciências Médicas e da Saúde - Ciências da Saúde - Saúde Pública e Saúde Ambiental
  • Ciências Médicas e da Saúde - Ciências da Saúde - Saúde Ocupacional

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Espanhol; Castelhano Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1)
Francês Utilizador elementar (A1) Utilizador elementar (A1)
Formação
Grau Classificação
2022/10/14 - 2023/07/13
Em curso
 Postgraduate Course in Health Quality Management (Pós-Graduação)
Universidade Católica Portuguesa Escola Superior Politécnica de Saúde Porto, Portugal
2018/01/01 - 2022/07/01
Concluído
 Doutoramento em Ciências Biomédicas (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
"Assessing the in vitro toxicity of engineered and airborne nanoceramics - contribution to the safe production and use of nanomaterials in the ceramic industry" (TESE/DISSERTAÇÃO)
2021/02/02
Frequentou
 Good Practices in In Vitro Research (Outros)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2019/05 - 2019/05
Frequentou
 JRC Summer School 2019: Non-Animal Approaches in Science Challenges & Future Directions, Joint Research Centre (Outros)
European Commission Joint Research Centre Ispra Sector, Itália
2019/04 - 2019/04
Concluído
 Applied In vitro Toxicology Course, jointly organized by the European Society of Toxicology In vitro and American Society for Cellular and Computational Toxicology (Outros)
Universitatea din Bucuresti Facultatea de Biologie, Roménia
2018/06 - 2018/06
Concluído
 EMBL Course: Hands-on Flow Cytometry - Learning by Doing!, The European Molecular Biology Laboratory (Outros)
European Molecular Biology Laboratory, Alemanha
2018/01 - 2018/01
Frequentou
 DiMoPEx Training School, COST Action CA15129 on "Risk assessment and communication" (Outros)
Instituto Nacional de Saúde Doutor Ricardo Jorge IP, Portugal
2017/11 - 2017/12
Concluído
 Intensive Course of Introduction to Biostatistics and its Applications (Outros)
Universidade do Porto Instituto de Saúde Pública, Portugal
2016/10 - 2016/11
Frequentou
 Drug Discovery Training School, COST Action CM1406 on “Epigenetic Chemical Biology” (Outros)
Fraunhofer-Einrichtung für Additive Produktionstechnologien IAPT, Alemanha
2016/06 - 2016/07
Concluído
 Course in Laboratory Animal Sciences – Category C with ELASA acreditation (Outros)
Universidade do Porto Faculdade de Medicina, Portugal
 18
2016/01 - 2016/01
Frequentou
 2nd Sustainable Nanotechnology Training School, EU FP7 Project SUN, MODENA COST Action TD1204 and ECONANOSORB (Outros)
Università Ca' Foscari, Itália
2015
Concluído
 Mestrado Integrado em Bioengenharia (Mestrado)
Universidade do Porto Faculdade de Engenharia, Portugal
"Moving into advanced nanomaterials. Toxicity of TiO2 nanoparticles immobilized in clay on human cell line." (TESE/DISSERTAÇÃO)
 16
2014/05 - 2014/05
Frequentou
 Spring School on Human Populations Studies with Genetic Biomarkers (Outros)
Universidade do Porto Instituto de Saúde Pública, Portugal

Instituto Nacional de Saúde Doutor Ricardo Jorge IP, Portugal
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2022/07 - Atual Pós-doutorado (Investigação) Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
Cooperativa de Ensino Superior Politécnico e Universitário, Portugal

Outros

Categoria Profissional
Instituição de acolhimento 		Empregador
2017/09 - 2022/07 PhD student in the CERASAFE Project SIINN/0004/2014 Universidade do Porto Instituto de Saúde Pública, Portugal
Instituto Nacional de Saúde Doutor Ricardo Jorge Porto, Portugal
2017/02/01 - 2017/08/31 Research fellow in the CERASAFE Project SIINN/0004/2014 Instituto Nacional de Saúde Doutor Ricardo Jorge IP, Portugal
2016 - 2017 Research trainee Universidade do Porto Unidade de Investigação em Epidemiologia, Portugal
2014/11/01 - 2015/10/06 Undergraduate trainee - Master's final project Instituto Nacional de Saúde Doutor Ricardo Jorge IP, Portugal
2013/11/01 - 2014/10/31 Undergraduate trainee Instituto Nacional de Saúde Doutor Ricardo Jorge IP, Portugal
2013/02/13 - 2013/06/14 Undergraduated trainee Centro Hospitalar do Porto, Portugal
Projetos

Bolsa

Designação Financiadores
2021 - 2024 4FirHealth - Firefighting occupational exposure and early effects on the health of operational forces
PCIF/SSO/0090/2019
 Fundação para a Ciência e Tecnologia
2016 - 2019 ERA-NET on Safe Implementation of Innovative Nanoscience and Nanotechnology (SIINN) CERASAFE- Safe production and Use of Nanomaterials in the Ceramic Industry
ERA-SIINN/0004/2014
Bolseiro de Doutoramento
Concluído

Outro

Designação Financiadores
2018 - 2021 Unravelling the mechanisms underlying the effects of metal-based nanoparticles on biological barriers - a contribution towards the implementation of the safe-by-design concept (NanoBioBarriers)
PTDC/MED-TOX/31162/2017
 Fundação para a Ciência e a Tecnologia
2018 - 2021 When old meets new: A novelty study on the human uptake, genotoxicity and immunotoxicity of nanoparticles and legacy contaminants mixtures (NanoLegaTox)
PTDC/SAU-PUB/29651/2017
 Fundação para a Ciência e a Tecnologia
2016 - 2019 ERA-NET SIINN NanoToxClass- Establishing nanomaterial grouping/ classification strategies according to toxicity and biological effects for supporting risk assessment
ERA-SIINN/0001/2013
Outra
Concluído
2016 - 2019 Controlling the degradation of MAGnesium alloys for biomedical applications using Innovative smart COATings (MAGICOAT)
PTDC/CTMBIO/2170/2014
Outra
Universidade do Porto Instituto de Saúde Pública, Portugal
Concluído
2014 - 2016 Valoración de posible neurotoxicidad de nanopartículas superparamagnéticas de óxidos de hierro (SPION) con aplicaciones en biomedicina
EM 2012/079
Outra
Xunta de Galicia, Espanha
Concluído
Produções

Publicações

Artigo em revista
  1. Bessa MJ; Sarmento B; Oliveira M; Rodrigues F. "In vitro data for fire pollutants: contribution of studies using human cell models towards firefighters' occupational.". Journal of toxicology and environmental health. Part B, Critical reviews (2023): http://europepmc.org/abstract/med/36883725.
    10.1080/10937404.2023.2187909
  2. Bessa MJ; Brandão F; Rosário F; Moreira L; Reis AT; Valdiglesias V; Laffon B; Fraga S; Teixeira JP. "Assessing the in vitro toxicity of airborne (nano)particles to the human respiratory system: from basic to advanced models.". Journal of toxicology and environmental health. Part B, Critical reviews (2023): http://europepmc.org/abstract/med/36692141.
    10.1080/10937404.2023.2166638
  3. Maria João Bessa; Fátima Brandão; Paul H. B. Fokkens; Daan L. A. C. Leseman; A. John F. Boere; Flemming R. Cassee; Apostolos Salmatonidis; et al. "Unveiling the Toxicity of Fine and Nano-Sized Airborne Particles Generated from Industrial Thermal Spraying Processes in Human Alveolar Epithelial Cells". International Journal of Molecular Sciences (2022): https://www.mdpi.com/1422-0067/23/8/4278.
    10.3390/ijms23084278
  4. Micaela Querido; Fernanda Rosário; Maria João Bessa; Francisca Mendes; José Carlos Teixeira; Joao Teixeira; Cristiana Pereira. "In Vitro Cyto- and Genotoxicity Assessment of Antibacterial Paints with Triclosan and Isoborneol". Toxics (2022): https://www.mdpi.com/2305-6304/10/2/58.
    10.3390/toxics10020058
  5. Maria João Bessa; Fátima Brandão; Paul H. B. Fokkens; Daan L. A. C. Leseman; A. John F. Boere; Flemming R. Cassee; Apostolos Salmatonidis; et al. "In Vitro Toxicity of Industrially Relevant Engineered Nanoparticles in Human Alveolar Epithelial Cells: Air–Liquid Interface versus Submerged Cultures". Nanomaterials (2021): https://www.mdpi.com/2079-4991/11/12/3225.
    10.3390/nano11123225
  6. Mar Viana; A Salmatonidis; S Bezantakos; C Ribalta; Natalia Moreno Palmerola; P Córdoba; F R Cassee; et al. "Characterizing the Chemical Profile of Incidental Ultrafine Particles for Toxicity Assessment Using an Aerosol Concentrator". Annals of Work Exposures and Health 65 8 (2021): 966-978. http://dx.doi.org/10.1093/annweh/wxab011.
    10.1093/annweh/wxab011
  7. Brandão F; Costa C; Bessa MJ; Dumortier E; Debacq-Chainiaux F; Hubaux R; Salmon M; et al. "Genotoxicity and Gene Expression in the Rat Lung Tissue following Instillation and Inhalation of Different Variants of Amorphous Silica Nanomaterials (aSiO2 NM).". Nanomaterials (Basel, Switzerland) (2021): http://europepmc.org/abstract/med/34200147.
    10.3390/nano11061502
  8. Bessa MJ; Brandão F; Fokkens P; Cassee FR; Salmatonidis A; Viana M; Vulpoi A; et al. "Toxicity assessment of industrial engineered and airborne process-generated nanoparticles in a 3D human airway epithelial in vitro model.". Nanotoxicology (2021): http://europepmc.org/abstract/med/33734024.
    10.1080/17435390.2021.1897698
  9. Rosário F; Bessa MJ; Brandão F; Costa C; Lopes CB; Estrada AC; Tavares DS; Teixeira JP; Reis AT. "Unravelling the Potential Cytotoxic Effects of Metal Oxide Nanoparticles and Metal(Loid) Mixtures on A549 Human Cell Line.". Nanomaterials (Basel, Switzerland) (2020): http://europepmc.org/abstract/med/32131449.
    10.3390/nano10030447
  10. Brandão F; Fernández-Bertólez N; Rosário F; Bessa MJ; Fraga S; Pásaro E; Teixeira JP; et al. "Genotoxicity of TiO2 Nanoparticles in Four Different Human Cell Lines (A549, HEPG2, A172 and SH-SY5Y).". Nanomaterials (Basel, Switzerland) (2020): http://europepmc.org/abstract/med/32120981.
    10.3390/nano10030412
  11. Bessa MJ; Brandão F; Viana M; Gomes JF; Monfort E; Cassee FR; Fraga S; Teixeira JP. "Nanoparticle exposure and hazard in the ceramic industry: an overview of potential sources, toxicity and health effects.". Environmental research (2020): http://europepmc.org/abstract/med/32155489.
    10.1016/j.envres.2020.109297
  12. S M M Oliveira; I L M Barzotto; Vieira L.; A Sene; P A Radi; S Fraga; M J Bessa; et al. "Tribocorrosion studies on diamond-like carbon film deposited by PECVD on 304 stainless steel in simulated body fluid". Biomedical Physics & Engineering Express 5 4 (2019): 045012-045012. http://dx.doi.org/10.1088/2057-1976/ab18e9.
    10.1088/2057-1976/ab18e9
  13. Fernández-Bertólez, N.; Costa, C.; Bessa, M.J.; Park, M.; Carriere, M.; Dussert, F.; Teixeira, J.P.; et al. "Assessment of oxidative damage induced by iron oxide nanoparticles on different nervous system cells". Mutation Research - Genetic Toxicology and Environmental Mutagenesis (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85057853764&partnerID=MN8TOARS.
    10.1016/j.mrgentox.2018.11.013
  14. Bessa, M.J.; Brandão, F.; Querido, M.M.; Costa, C.; Pereira, C.C.; Valdiglesias, V.; Laffon, B.; et al. "Optimization of the harvesting and freezing conditions of human cell lines for DNA damage analysis by the alkaline comet assay". Mutation Research - Genetic Toxicology and Environmental Mutagenesis (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85058227943&partnerID=MN8TOARS.
    10.1016/j.mrgentox.2018.12.002
  15. Bessa, M.J.; Costa, C.; Reinosa, J.; Pereira, C.; Fraga, S.; Fernández, J.; Bañares, M.A.; Teixeira, J.P.. "Moving into advanced nanomaterials. Toxicity of rutile TiO2 nanoparticles immobilized in nanokaolin nanocomposites on HepG2 cell line". Toxicology and Applied Pharmacology 316 (2017): 114-122. http://www.scopus.com/inward/record.url?eid=2-s2.0-85008420158&partnerID=MN8TOARS.
    10.1016/j.taap.2016.12.018
  16. Mesquita, B.; Lopes, I.; Silva, S.; Bessa, M.J.; Starykevich, M.; Carneiro, J.; Galvão, T.L.P.; et al. "Gold nanorods induce early embryonic developmental delay and lethality in zebrafish (Danio rerio)". Journal of Toxicology and Environmental Health - Part A: Current Issues 80 13-15 (2017): 672-687. http://www.scopus.com/inward/record.url?eid=2-s2.0-85023174720&partnerID=MN8TOARS.
    10.1080/15287394.2017.1331597
  17. Bessada, S.M.F.; Barreira, J.C.M.; Santos, J.; Costa, C.; Pimentel, F.B.; Bessa, M.J.; Teixeira, J.P.; Oliveira, M.B.P.P.. "Evaluation of the cytotoxicity (HepG2) and chemical composition of polar extracts from the ruderal species Coleostephus myconis (L.) Rchb.f.". Journal of Toxicology and Environmental Health - Part A: Current Issues 80 13-15 (2017): 641-650. http://www.scopus.com/inward/record.url?eid=2-s2.0-85019619598&partnerID=MN8TOARS.
    10.1080/15287394.2017.1286915
  18. Costa, C.; Brandão, F.; Bessa, M.J.; Costa, S.; Valdiglesias, V.; Kiliç, G.; Fernández-Bertólez, N.; et al. "In vitro cytotoxicity of superparamagnetic iron oxide nanoparticles on neuronal and glial cells. Evaluation of nanoparticle interference with viability tests". Journal of Applied Toxicology 36 3 (2016): 361-372. http://www.scopus.com/inward/record.url?eid=2-s2.0-84955703748&partnerID=MN8TOARS.
    10.1002/jat.3213
  19. Valdiglesias, V.; Fernández-Bertólez, N.; Kiliç, G.; Costa, C.; Costa, S.; Fraga, S.; Bessa, M.J.; et al. "Are iron oxide nanoparticles safe? Current knowledge and future perspectives". Journal of Trace Elements in Medicine and Biology 38 (2016): 53-63. http://www.scopus.com/inward/record.url?eid=2-s2.0-84962022085&partnerID=MN8TOARS.
    10.1016/j.jtemb.2016.03.017
  20. Soto-Zarazúa, M.G.; Bah, M.; García-Alcocer, M.G.; Berumen, L.C.; Costa, C.S.; Bessa, M.J.; Rodrigues, F.; Teixeira, J.P.; Oliveira, M.B.P.P.. "Assessment of Beneficial and Possible Toxic Effects of Two New Alfalfa-Derived Shelf Products". Journal of Medicinal Food 19 10 (2016): 970-977. http://www.scopus.com/inward/record.url?eid=2-s2.0-84992381847&partnerID=MN8TOARS.
    10.1089/jmf.2016.0024
  21. Bessa, M.J.; Costa Rego, M.; Rocha, E.; Pessanha, J.; leal, C.; Guimarães, J.M.; Carlos Oliveira, J.; Sousa, M.. "Semen parameters and their influence on pregnancy after assisted reproduction: Report of the Hospital Centre of Porto". Revista Internacional de Andrologia 13 1 (2015): 27-36. http://www.scopus.com/inward/record.url?eid=2-s2.0-84924664145&partnerID=MN8TOARS.
    10.1016/j.androl.2014.05.001
Capítulo de livro
  1. Silva, A.M.; Bessa, M.J.; Rodrigues, Francisca. "Cell-based in vitro models for dermal permeability studies". In Concepts and Models for Drug Permeability Studies – Cell and Tissue-Based In Vitro Culture Models. 2023.
    No prelo
  2. Bessa, M.J.; Teixeira, J.P.; Costa, C.. "Human exposure to titanium dioxide nanoparticles and current toxicological data: An overview". 2017.
Poster em conferência
  1. Bessa, M.J.; Teixeira, J.; Delerue-Matos, Crstina; Sarmento, Bruno; Rodrigues, Francisca; Oliveira, M.M.. "In vitro toxicity assessment of firefighters’ breathable air collected on polyurethane foams in human lung epithelial cells". Trabalho apresentado em II TOXRUN International Congress 2023, 2023.
  2. Teixeira, J.; Bessa, M.J.; Delerue-Matos, Crstina; Sarmento, Bruno; Rodrigues, Francisca. "Firefighters’ exposure to airborne carcinogenic polycyclic aromatic hydrocarbons during controlled forest fires and related health risks". Trabalho apresentado em International Firefighter Cancer Symposium (IFCS), 2023.
  3. Bessa, M.J.; Brandão, F.; A. Salmatonidis; Vulpoi, A.; Viana, M.; Cassee, Flemming; Fraga, F.; Teixeira, J.P.. "Cyto-, geno- and immunotoxicity of engineered or ceramic-derived airborne nanoparticles in 3D human bronchial epithelial cultures.". Trabalho apresentado em 2nd Meeting of the PhD in Biomedical Sciences of ICBAS, 2019.
  4. Brandão, F.; Costa, C.; Bessa, M.J.; Andrea Haase; Fraga, S.; Teixeira, J.P.. "Evaluation of DNA damage in the rat lung after inhalation exposure to TiO2 and SiO2 nanoparticles.". Trabalho apresentado em 55th Congress of the European Societies of Toxicology (EUROTOX 2019), 2019.
  5. Brandão, F.; Bessa, Maria João; Costa, C.; Andrea Haase; Fraga, S.; Teixeira, J.P.. "Assessment of DNA damage in the lung tissue of rats exposed by inhalation to TiO2 and SiO2 nanoparticles.". Trabalho apresentado em The International Comet Assay Workshops (ICAW 2019), 2019.
  6. Bessa, M.J.; Brandão, F.; Fokkens, P.; A. Salmatonidis; Viana, M.; Cassee, Flemming; Texeira, J.P.. "Toxicity assessment of engineered and process-generated airborne nanoparticles in human alveolar epithelial A549 cells.". Trabalho apresentado em 6th International Conference nanoSAFE 2018, 2018.
  7. Fraga, F.; Bessa, M.J.; Brandão, F.; Fokkens, P.; A. Salmatonidis; Viana, M.; Cassee, Flemming; Teixeira, J.P.. "Toxicity of ceramic nanoparticles in human alveolar epithelial A549 cells at air-liquid interface.". Trabalho apresentado em 6th International Conference nanoSAFE 2018, 2018.
  8. Brandão, F.; Fraga, S.; Costa, C.; Bessa, M.J.; A. Haase; Teixeira, J.P.. "Toxicity of different classes of manufactured nanomaterials in alveolar epithelial cells.". Trabalho apresentado em 6th International Conference nanoSAFE 2018, 2018.
  9. Oliveira, S.M.M.; Viera, L.; Sene, A.C.A.; Fraga, S.; Bessa, M.J.; Teixeira, J.P.; Carvalho, I.C.S.; Silva, N.S.. "Effect of DLC films on viability and genotoxicity in A172 human glioblastoma". Trabalho apresentado em 4th International Congress on Occupational & Environmental Toxicology, 2018.
  10. Brandão, F.; Fraga, S.; Costa, C.; Bessa, M.J.; A. Haase; Teixeira, J.P.. "Cytotoxicity and DNA damage of a panel of manufactured nanomaterials in rat alveolar epithelial RLE-6TN cells.". Trabalho apresentado em 20th International Congress on In vitro Toxicology (ESTIV 2018), 2018.
  11. Fraga, S.; Bessa, M.J.; Brandão, F.; Fokkens, P.; A. John F. Boere; D. Leseeman; A. Salmatonidis; et al. "Toxicity of ceramic nanoparticles in human alveolar epithelial A549 cells at the air-liquid interface.". Trabalho apresentado em 54th Congress of the European Societies of Toxicology (EUROTOX 2018), 2018.
  12. Brandão, F.; Bessa, M.J.; Costa, C.; Fraga, S.; A. Haase; Teixeira, J.P.. "Insights into the role of the physicochemical properties in the toxicity of SiO2 nanoparticles in rat alveolar epithelial RLE-6TN cells.". Trabalho apresentado em 54th Congress of the European Societies of Toxicology (EUROTOX 2018), 2018.
  13. Bessa, M.J.; Fraga, F.; Brandão, F.; Fokkens, P.; A. John F. Boere; Daan L. A. C. Leseman; A. Salmatonidis; et al. "Moving towards an advanced method to assess the toxicity of ceramic nanoparticles in human alveolar epithelial cells.". Trabalho apresentado em 1st Meeting of the PhD in Biomedical Sciences of ICBAS, 2018.
  14. Bessa, M.J.; Fraga, S.; Brandão, F.; Fokkens, P.; A. John F. Boere; Daan L. A. C. Leseman; A. Salmatonidis; et al. "Pairwise toxicity evaluation of ceramic nanoparticles in submerged and air-liquid interface cultures of human alveolar epithelial A549 cells.". Trabalho apresentado em 20th International Congress on In vitro Toxicology (ESTIV 2018), 2018.
  15. Brandão, F.; Bessa, M.J.; Costa, C.; Fraga, S.; A. Haase; Teixeira, J.P.. "Role of surface capping on the cytotoxicity of silica nanoparticles in rat alveolar epithelial cells.". Trabalho apresentado em 53rd Congress of the European Societies of Toxicology (EUROTOX 2017), 2017.
  16. Bessa, M.J.; Fraga, S.; Brandão, F.; Querido, M.M.; C. Costa; Teixeira, J.P.; Fraga, F.. "Freezing procedure optimization of two human cell lines for comet assay analysis.". Trabalho apresentado em 12th International Comet Assay Workshop (ICAW, 2017), 2017.
  17. Bessa, M.J.; Reinosa, J.J.; Fernandez, J.F.; Bañares, M.A.; Teixeira, J.P.; Costa, C.. "How important is the study of assay interference prior to nanotoxicity assessment? Case study with TiO2 Nanoparticles immobilized in nanokaolin substrates.". Trabalho apresentado em International Conference on Occupational & Environmental Toxicology, 2016.
  18. Bessa, M.J.; Reinosa, J.J.; Fernandez, J.F.; Bañares, M.A.; Teixeira, J.P.; Costa, C.. "In vitro toxicity of TiO2 nanoparticles immobilized on clay to human hepatic cells.". Trabalho apresentado em The Society of Toxicology 55th Annual Meeting and ToxExpo, 2016.
  19. Bessa, M.J.; Reinosa, J.J.; Fernandez, J.F.; Bañares, M.A.; Teixeira, J.P.; Costa, C.. "Cytotoxicity of Clay-TiO2 nanostructures in human HepG2 cells.". Trabalho apresentado em 9th Congress of Toxicology in Developing Countries and XIX Brazilian Congress of Toxicology (CBTOX), 2015.
  20. Costa, C.; Brandão, F.; Bessa, M.J.; Costa, S.; Valdiglesias, V.; Gozde Kiliç; Fernández-Bertólez, N.; et al. "In vitro toxicity screening of silica-coated superparamagnetic iron oxide nanoparticles in glial cells.". Trabalho apresentado em 1st Congress of the European Societies of Toxicology (EUROTOX 2015), 2015.
  21. Costa, C.; Gozde Kiliç; Brandão, F.; Bessa, M.J.; Costa, S.; Pásaro, E.; Valdiglesias, V.; Blanca Laffon; Teixeira, J.P.. "Cytotoxicity of iron oxide nanoparti cles with different coatings in human neuronal cells.". Trabalho apresentado em 50th Congress of the European Societies of Toxicology (EUROTOX 2014), 2014.
Resumo em conferência
  1. Bessa, M.J.; Teixeira, J.; Delarue-Matos, C.; Sarmento, Bruno; Rodrigues, Francisca; Oliveira, M.. "In vitro toxicity assessment of firefighters’ breathable air collected on polyurethane foams in human lung epithelial cells". Trabalho apresentado em II TOXRUN International Congress 2023, Porto, 2023.
    Publicado
  2. S. Fraga; M.J. Bessa; M.F.P. Brandão; P. Fokkens; J.F. Boere; D. Leseeman; A. Salmatonidis; et al. "Toxicity of ceramic nanoparticles in human alveolar epithelial A549 cells at the air-liquid interface". 2018.
    10.1016/j.toxlet.2018.06.924
  3. M.F.P. Brandão; M.J. Bessa; C. Costa; S. Fraga; A. Haase; J.P. Teixeira. "Insights into the role of the physicochemical properties in the toxicity of SiO2 nanoparticles in rat alveolar epithelial RLE-6TN cells". 2018.
    10.1016/j.toxlet.2018.06.921
  4. Bessa, M.J.; Brandão, F.; Querido, M.M.; Costa, C.; Teixeira, J.P.; Fraga, S.. "Freezing procedure optimization of two human cell lines for comet assay analysis.". 2017.
    10.1093/mutage/gex037
  5. Fátima Brandão; Maria João Bessa; Carla Costa; Sónia Fraga; Andrea Haase; João Paulo Teixeira. "Role of surface capping on the cytotoxicity of silica nanoparticles in rat alveolar epithelial cells". 2017.
    10.1016/j.toxlet.2017.07.526
  6. Carla Costa; Gozde Kiliç; Fátima Brandão; Maria João Bessa; Solange Costa; Eduardo Pásaro; Vanessa Valdiglesias; Blanca Laffon; João Paulo Teixeira. "Cytotoxicity of iron oxide nanoparticles with different coatings on human neuronal cells". 2014.
    10.1016/j.toxlet.2014.06.673
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2020/02 In vitro toxicity of ceramic nanoparticles in 3D human airway epithelial cultures. L Annual Meeting of the Portuguese Pharmacological Society; XXXVII Meeting of Clinical Pharmacology, XIX Meeting of Toxicology
Portuguese Pharmacological Society (Coimbra, Portugal)
2019/06 Assessment of DNA damage in the lung tissue of rats exposed by inhalation to TiO2 and SiO2 nanoparticles. The International Comet Assay Workshops (ICAW 2019)
(Pushchino, Rússia)
2019/02 In vitro toxicity of ceramic nanoparticles in human alveolar cells at submerged and air-liquid interface conditions. XLIX Annual Meeting of the Portuguese Pharmacological Society; XXXVI Meeting of Clinical Pharmacology, XVIII Meeting of Toxicology
(Porto, Portugal)
2019/01 Pairwise toxicity evaluation of ceramic nanoparticles exposure in human alveolar epithelial A549 cells at submerged and air-liquid cultures. Award Winners Series Webinar on “Nanoceramic pulmonary toxicity & reproducible cell line technology” jointly organized by ESTIV (European Society of Toxicology In vitro) and ASCCT (American Society for Cellular and Computational Toxicology)
2018/10 In vitro toxicity assessment of engineered nanoparticles used in the ceramic industry. 4th International Congress on Occupational & Environmental Toxicology
(Matosinhos, Portugal)
2018/10 Toxicity of different classes of manufactured nanomaterials in rat alveolar epithelial RLE-6TN cells. 4th International Congress on Occupational & Environmental Toxicology
(Porto, Portugal)
2017/08 Freezing procedure optimization of two human cell lines for comet assay analysis. 12th International Comet Assay Workshop (ICAW, 2017)
(Pamplona, Espanha)
2016/03 In vitro toxicity of TiO2 nanoparticles immobilized on clay to human hepatic cells. The Society of Toxicology 55th Annual Meeting and ToxExpo
(New Orleans, Louisiana, Estados Unidos)
2016/02 Toxicity outcomes of TiO2 nanoparticles immobilized on clay nanocomposites in human hepatic cell line. XLVI Annual Meeting of Portuguese Pharmacological Society, XXXIV Annual Meeting of Clinical Pharmacology, XV Annual Meeting of Toxicology
Portuguese Pharmacological Society (Porto, Portugal)
2015/09 Understanding the toxicity outcomes of kaolinite for future nanocomposite applications. Global Environmental Health Forum, IFEH 1st World Academic Congress on Environmental Health
(Coimbra, Portugal)

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação) 		Instituição / Organização
2018 - 2018 4th International Congress on Occupational & Environmental Toxicology (ICOETOX 2018) (2018/10/24 - 2018/10/26)
Congresso (Membro da Comissão Organizadora)
 Universidade do Porto Instituto de Saúde Pública, Portugal

Instituto Nacional de Saúde Doutor Ricardo Jorge Porto, Portugal

Júri de grau académico

Tema
Tipo de participação 		Nome do candidato (Tipo de grau)
Instituição / Organização
2023/07/11 Characterization of cytotoxic mechanism of new molecules with antitumor potential
Arguente principal
 Eliseba Castro (Outro)
Cooperativa de Ensino Superior Politécnico e Universitário, Portugal

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2019/06 - Atual Nanotoxicology Seminar (Licenciatura) Escola Superior de Saúde do Politécnico do Porto, Portugal
2023/01 - 2023/01 Introduction to in vitro toxicity assessment (Doutoramento) Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
Distinções

Prémio

2020 IACOBUS Program Award for Best Paper entitled “Optimization of the harvesting and freezing conditions of human cell lines for DNA damage analysis by the alkaline Comet assay” from Mutation Research - Genetic Toxicology and Environmental Mutagenesis
Xunta de Galicia, Espanha

Comissao de Coordenacao e Desenvolvimento Regional do Norte, Portugal
2019 EUROTOX fellowship support to attend “ESTIV/NVT Applied In Vitro Toxicology Course 2019”
EUROTOX, Bélgica
2018 Travel Award for participation EMBL Course: Hands-on Flow Cytometry - Learning by Doing!
European Molecular Biology Laboratory, Alemanha
2018 Best Poster Communication in the ESTIV 2018 Congress - Applied In Vitro Toxicology
20th International European Society of Toxicology In Vitro Congress 2018, Alemanha
2017 PhD Scholarship (SFRH/BD/120646/2016)
2016 Travel Award for participation in the 2nd Sustainable Nanotechnology School
MODENA Cost Action, Itália
2016 Travel Award for participation in Drug Discovery Training School
COST Action CM1406, Alemanha