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Margarida Brás is a true enthusiast for immunology, regenerative medicine, stem cell biology and cell therapies and she is currently a research assistant at Filipe Pereira's Lab at the Center for Neuroscience and Cell Biology (CNC-Coimbra). She holds a Bachelor's degree in Biomedical Sciences from the University of Aveiro. Throughout that period, she interned at the iBiMED Institute and was also involved in the organization of scientific events as part of a multidisciplinary team in the junior enterprise Scientific Junior Value. She completed her master´s degree in Molecular Genetics and Biomedicine at Nova University Lisbon in 2022. During the master's program, she had the opportunity to develop her dissertation project focused on the mechanisms of immune modulation during skeletal muscle regeneration at the Aging and Tissue Repair joint lab, Institute of Molecular Medicine (iMM), Lisbon. After finishing this project, she became a research fellow in the same lab, gaining further hands-on experience in cell culture, flow cytometry, microscopy, molecular biology, and data analysis. Her research at the Aging and Tissue Repair Lab contributed to two distinct publications, exposing her to the rigorous and challenging process of research article submission and peer review. She joined Filipe Pereira’s Immune Cell Reprogramming Lab at CNC as a research assistant in 2024. In her current lab, she enhanced her technical expertise, learning about cell reprogramming approaches and related techniques such as molecular cloning and viral production. She also improved her literature review and scientific writing skills by developing a review manuscript as first author and co-reviewed a manuscript for Science, a challenge that stimulated critical thinking and attention to detail. For 3.5 months, she joined the Pereira Lab team in Lund (Sweden), gaining experience in embryonic stem cell culture and improving her molecular biology expertise. Additionally, over the past years, she has participated in different courses and workshops to further improve her expertise, including training in flow cytometry and data analysis, iPSCs culture, Immunology, and Laboratory Animal Science.
Identificação

Identificação pessoal

Nome completo
MARIA MARGARIDA FERREIRA BRÁS
Data de nascimento
1999/04/28
Género
Feminino

Nomes de citação

  • Margarida F. Brás

Identificadores de autor

Ciência ID
701C-23A8-8156
ORCID iD
0000-0003-4155-8249

Endereços de correio eletrónico

  • mmfbras@gmail.com (Profissional)
  • mbras@medicina.ulisboa.pt (Profissional)
  • mbras@uc.pt (Profissional)

Websites

  • www.linkedin.com/in/margarida-brás-4b58371a9 (Rede social)

Domínios de atuação

  • Ciências Médicas e da Saúde
  • Ciências Médicas e da Saúde - Medicina Básica - Imunologia
  • Ciências Médicas e da Saúde - Biotecnologia Médica - Diagnóstico e Terapias de Base Genética

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Espanhol; Castelhano Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1)
Formação
Grau Classificação
2024/01/05 - 2025/12
Em curso
Clinical Investigator European Certificate - CLIC 1 e 2 (Curso de Especialização Tecnológica)
Universidade Nova de Lisboa Medical School, Portugal

Universidade de Aveiro Associação para a Formação Profissional e Investigação, Portugal
2025/03/17 - 2025/06/12
Em curso
1st SPI Advanced Immunology Course (Outros)
Sociedade Portuguesa de Imunologia, Portugal
2024/11 - 2025/06
Em curso
Training in Laboratory Animal Science (LAS) - Rodents and Lagomorphs (Outros)
Lunds universitet Medicinska fakulteten, Suécia
2024/11/18 - 2024/11/22
Concluído
Handling, maintenance and understanding of human Pluripotent Stem Cells (iPSCs) (Outros)
Lunds universitet Medicinska fakulteten, Suécia
2023/05/08 - 2023/05/12
Concluído
Basic & Advanced module of FLxFlowCourse: Principles and Applications of Flow Cytometry (Outros)
Fundação Champalimaud, Portugal
2020/09 - 2022/11/29
Concluído
Genética Molecular e Biomedicina (Mestrado)
Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
""Mechanisms of immune modulation mediated by Mesencephalic Astrocyte-derived Neurotrophic Factor"" (TESE/DISSERTAÇÃO)
19
2017/09 - 2020/06/29
Concluído
Ciências Biomédicas (Licenciatura)
Especialização em Biologia Molecular
Universidade de Aveiro, Portugal
18
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento
Empregador
2024/02/01 - Atual Assistente de Investigação (carreira) (Investigação) Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia, Portugal
Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia, Portugal
2024/09/03 - 2024/12/18 Investigador visitante (Investigação) Lunds universitet Medicinska fakulteten, Suécia
Lunds universitet Institutionen för laboratoriemedicin, Suécia
2022/11/07 - 2023/12/31 Assistente de Investigação (carreira) (Investigação) Universidade de Lisboa Instituto de Medicina Molecular, Portugal
Universidade de Lisboa Instituto de Medicina Molecular, Portugal
2019/06 - 2019/09 Estagiário de Investigação (Investigação) Universidade de Aveiro Instituto de Biomedicina, Portugal
Universidade de Aveiro Instituto de Biomedicina, Portugal
Projetos

Bolsa

Designação Financiadores
2024/02/01 - Atual CiNTech - Technological Hub for Innovation, Translation and Industrialization of Complex Injectable Drugs
C644865576-00000005
Bolseiro de Investigação
Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia, Portugal
Governo da República Portuguesa
Em curso
2022/11 - 2023/12/31 Mechanisms of tissue ageing and repair: roadblocks to stem cell-based therapies
IG4448
Bolseiro de Investigação
Instituto de Medicina Molecular, Portugal
Concluído
Produções

Publicações

Artigo em revista
  1. Sousa, Neuza S.; Bica, Marta; Brás, Margarida F.; Sousa, Ana C.; Antunes, Inês B.; Encarnação, Isabel A.; Costa, Tiago M.; et al. "The immune landscape of murine skeletal muscle regeneration and aging". Cell Reports 43 11 (2024): 114975. https://doi.org/10.1016/j.celrep.2024.114975.
    10.1016/j.celrep.2024.114975
  2. Sousa, Neuza S.; Brás, Margarida F.; Antunes, Inês B.; Lindholm, Päivi; Neves, Joana; Sousa-Victor, Pedro. "Aging disrupts MANF-mediated immune modulation during skeletal muscle regeneration". Nature Aging 3 5 (2023): 585-599. https://doi.org/10.1038/s43587-023-00382-5.
    Publicado • 10.1038/s43587-023-00382-5
Tese / Dissertação
  1. "Mechanisms of immune modulation mediated by Mesencephalic Astrocyte-derived Neurotrophic Factor". Mestrado, Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, 2022. http://hdl.handle.net/10362/155872.
Atividades

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação)
Instituição / Organização
2020 - 2020/05 Scale Up- Build Your Own Future (Online) (2020/05/13 - 2020/05/16) Scientific Junior Value,, Portugal
2020 - 2020 Aveiro Tech Business (Online) (2020/07/03 - 2020/07/03)
Conferência (Membro da Comissão Organizadora)
Scientific Junior Value,, Portugal
2019 - 2019 BrainLoad - Power Up Your Knowledge! (2019/11/27 - 2019/11/27) Scientific Junior Value,, Portugal

Participação em evento

Descrição da atividade
Tipo de evento
Nome do evento
Instituição / Organização
2022/03/31 - 2022/04/01 Seminar and training attendance "Cytometry Data Analysis in FlowJo v10" An event organized by FLxFlow - The Lisbon Flow Cytometry Network. Attendance in both sessions, "Intro to FlowJO v10" and "Advanced Tools & Plugins," given by Serena Di Cecilia, PhD
Oficina (workshop)
Cytometry Data Analysis in FlowJo v10
Instituto de Medicina Molecular, Portugal
2019/03/27 - 2019/04/03 Scale UP - Build Your Own Future: A career development event designed to enhance participants' general skills and prepare them for the job market. Day 1: Focuses on teamwork and strategy development, culminating in a competition where the winning team earns internships at companies represented by the jury. Day 2: Starts with lectures on soft skills development, followed by practical job simulations with invited companies (including GSK). This event is a unique opportunity for networking, skill-building, and potential career opportunities Scale UP - Build Your Own Future
Scientific Junior Value,, Portugal
2019/03/13 - 2019/03/16 X National Biomedical Sciences Symposium
Congresso
X National Biomedical Sciences Symposium
Universidade de Aveiro, Portugal
2018/11/20 - 2018/11/20 Signaling Afternoon- Event organized by students of the master's degree in molecular biomedicine Signaling Afternoon
Universidade de Aveiro, Portugal
2018/11/18 - 2018/11/18 BrainLoad - Power Up Your Knowledge! The event showcases advancements in scientific research, with a special focus on Biosciences, taking place in Portugal's most prestigious research centers and laboratories. It features lectures where researchers present their scientific projects, followed by a roundtable discussion that allows participants to ask questions and debate controversial topics.
Conferência
BrainLoad - Power Up Your Knowledge!
Scientific Junior Value,, Portugal

Membro de associação

Nome da associação Tipo de participação
2019/04/01 - 2020/07/31 Junior Enterprise Scientific Junior Value Organization of Scientific Events - Member of Scientific Affairs Department

Revisão ad hoc de artigos em revista

Nome da revista (ISSN) Editora
2024/11/20 - 2024/12/20 Science ( 0036-8075)

Tutoria

Tópico Nome do aluno
2019/09 - 2020/06 Mentor of 1st year students within the Tutoring Program of the University of Aveiro 3 Students
Distinções

Prémio

2020 Caixa Geral de Depósitos Award for Best Student in Biomedical Sciences in 2019/2020
Universidade de Aveiro, Portugal

Caixa Geral de Depositos, Portugal

Outra distinção

2019 Academic merit Scholarship 2019
Universidade de Aveiro, Portugal
2018 Academic Merit Scholarship 2018
Universidade de Aveiro, Portugal
2017 Academic Merit Scholarship 2017
Universidade de Aveiro, Portugal