Ana Luisa Moreira de Carvalho (351C-DCB9-6912)

Curriculum Vitae

Ana Luisa Moreira de Carvalho

I've completed PhD in Structural Biology in 2002 and presently hold a position as Research Assistant Professor at UCIBIO-NOVA, started in 2003. My present research interests are focused in the search for uncharacterised biological protein-carbohydrate interactions with potential biotechnological use in nutrition, in pharma and in the biofuel industry. For this, among other structural biology and biophysics methods, I use the powerful information provided by X-ray Crystallography. The atomic level information obtained allows drawing conclusions related to macromolecular interactions, either protein-protein or protein-ligand. Additionally, I've also been strongly dedicated to the study of the phenomena behind protein crystallisation and new methods to improve it. I have completed the supervision of one PhD student (awarded the Antonio Xavier Prize for the Best Thesis in 2013) and presently supervise 5 PhD students, from the MolBios and Biochemistry Doctoral programs, 3 of them concluding their Theses in 2020. I have also trained 6 MSc students, 5 hired Post-Doctoral Fellows, and 14 other post-graduate students. Additionally, I have tutored 17 under-graduate students. In the beginning of my contract as Researcher, I held a contract as Invited Assistant Professor of FCT-NOVA, for 5 years. Additionally, I was a member of the Scientific Council of FCT-NOVA, from 2012 to 2015. I keep a regular support to 2nd and 3rd cycles in the Biochemistry section in FCT-NOVA and other institutions, when invited. I have organised several hands-on advanced courses, notably 2 editions (2014 and 2015) of the Instruct-ERIC/COST-supported international course ISBIO (https://eventos.fct.unl.pt/isbio) and a 3rd edition to be held in July 2020. As Principal Investigator, I have coordinated 4 national FCT-MCTES funded projects and was member of team in 12 other projects. I have also integrated the winning teams of the Santander-Totta Scientific Merit Award, in 2012, and the Bluepharma Innovation Award, in 2013. Up to January 2020, my research activity has produced 49 peer-reviewed publications and 5 book chapters, 20 invited and 17 co-authored oral communications. I have co-authored more than 80 poster communications (6 awarded as Best Poster). I’m Guest Editor of a Special Issue from open access journal Crystals (MDPI Publishers; https://www.mdpi.com/journal/crystals/special_issues/novel_protein). Citation metrics in ResearchID (G- 5638-2011) indicate 45 articles with citation data, with more than 1100 citations (24.9 per article) and an h-index of 17. As science outreach activities, I have dynamized the celebrations of the International Year of Crystallography, in 2014, and the International Year of Chemistry, in 2011. From 2006-2012, I was regular translator of the Science-in-School magazine. I maintain the group's social network website (https://www.facebook.com/XtalNOVA) and my own (https://docentes.fct.unl.pt/almc/). From January 2020, I was assigned duties as Ambassador for the Science Communication & Outreach of the XTAL research lab.

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Identificação

Identificação pessoal

Nome completo: Ana Luisa Moreira de Carvalho
Data de nascimento: 1972/08/07

Nomes de citação

Carvalho, Ana Luísa
Carvalho, Ana L.
Carvalho, AL

Identificadores de autor

Ciência ID: 351C-DCB9-6912
ORCID iD: 0000-0002-3824-0240
Google Scholar ID: IQgJcAAAAJ
Researcher Id: G-5638-2011
Scopus Author Id: 57195976906

Endereços de correio eletrónico

almc@fct.unl.pt (Profissional)

Telefones

Telefone

2948300 Ext.: 10940 (Profissional)

Moradas

UCIBIO, Departamento de Quimica, FCT-UNL, 2829-516, Caparica, Almada, Portugal (Profissional)

Websites

https://www.facebook.com/XtalNOVA (Rede social)
http://orcid.org/0000-0002-3824-0240 (Profissional)
http://www.researcherid.com/rid/G-5638-2011 (Profissional)
http://www.ucibio.pt/people/ana-luisa-carvalho (Profissional)
https://publons.com/researcher/1327109/ana-luisa-carvalho/publications/ (Profissional)
http://docentes.fct.unl.pt/almc (Académico)
https://sites.fct.unl.pt/xtal/ (Académico)
https://research.unl.pt/en/persons/ana-luisa-carvalho(671f7779-7995-4ac5-937e-c5293aea20ee).html (Académico)

Domínios de atuação

Ciências Naturais - Ciências Biológicas - Bioquímica
Ciências Exatas - Química
Ciências Naturais - Ciências Biológicas - Biofísica
Ciências Naturais - Ciências Biológicas - Métodos de Investigação Bioquímica

Idiomas

Idioma	Conversação	Leitura	Escrita	Compreensão	Peer-review
Português (Idioma materno)
Inglês	Utilizador proficiente (C2)	Utilizador proficiente (C2)	Utilizador proficiente (C2)	Utilizador proficiente (C2)	Utilizador proficiente (C2)
Francês	Utilizador elementar (A2)	Utilizador proficiente (C1)	Utilizador independente (B1)	Utilizador independente (B1)	Utilizador elementar (A1)
Espanhol; Castelhano	Utilizador independente (B2)	Utilizador proficiente (C2)	Utilizador independente (B1)	Utilizador proficiente (C2)	Utilizador elementar (A1)

Formação

	Grau	Classificação
2002/12/01 - 2003/11/14 Concluído	Structural characterization of cellulosomal protein complexes: study of function and assembly mechanisms (Pós-doutoramento) Especialização em Structural Biology Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal Universidade Nova de Lisboa, Portugal
1998/02/01 - 2002/11/05 Concluído	Biochemistry (Doutoramento) Especialização em Structural Biology Universidade Nova de Lisboa, Portugal Centro de Investigaciones Biológicas, Espanha "Caracterização Estrutural e Bioquímica de uma Protease de Serina (Calicreína) Isolada do Plasma Seminal de Cavalo." (TESE/DISSERTAÇÃO)	Approved by unanimity
1996/09/01 - 1998/01/31 Concluído	MSc in Biophysics and Biomedical Enginneering (Mestrado) Especialização em Biophysics Universidade de Lisboa Instituto de Biofísica e Engenharia Biomédica, Portugal "aSFP, an acidic Seminal Fluid Protein: crystallization, heavy-atom derivatization and X-ray diffraction data collection" (TESE/DISSERTAÇÃO)	A, Very Good
1989/09/01 - 1992/06/01 Concluído	Degree of Proficiency in English (Diploma de especialização) British Council Lisbon, Portugal	Grade C

Percurso profissional

Ciência

2003/11/15 - Atual	Investigador Auxiliar (carreira) (Investigação) REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2002 - 2003	Pós-doutorado (Investigação) Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
2000/03 - 2000/04	Estagiário de Investigação (Investigação) Centro de Investigaciones Biológicas, Espanha
2000 - 2000	Estagiário de Investigação (Investigação) Instituto de Biomedicina de Valencia, Espanha
1999/06 - 1999/07	Estagiário de Investigação (Investigação) Max-Planck-Institut für Biochemie, Alemanha
1998/11 - 1998/12	Estagiário de Investigação (Investigação) Max-Planck-Institut für Biochemie, Alemanha
1998/03 - 1998/03	Estagiário de Investigação (Investigação) Centro de Investigaciones Biológicas, Espanha
1994/08 - 1994/12	Estagiário de Investigação (Investigação) Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal

Docência no Ensino Superior

2003/11/01 - 2007/02/28

Professor Auxiliar Convidado (Docente Universitário)

Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Cargos e Funções

2020/02/01 - Atual	Member of the Scientific Commission of the Biochemistry Section Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2016 - Atual	Member of the Commission for the Management of Equipment and other Resources REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2015/01/01 - Atual	Responsible for the X-ray Diffraction Facility of UCIBIO-FCT-NOVA REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2004/01/01 - Atual	Coordinator of the UCIBIO team, part of the Portuguese Block Allocation Group (BAG-Portugal), at the European Synchrotron Radiation Facility (ESRF) REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2015 - 2020	Substitute member of the Scientific Council of FCT-NOVA Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2012/10/01 - 2015/07/31	Member of the Scientific Council of FCT-NOVA Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2012 - 2014	Member of the Commission for the Scientific Matters of the Scientific Council Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2009/11/01 - 2012/10/31	Substitute member of the Scientific Council of FCT-NOVA Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Projetos

Bolsa

	Designação	Financiadores
2020 - Atual	GlycoMed: Uma nova geração de enzimas para a degradação de biofilmes e modulação da resposta imunitária no cancro (A new generation of enzymes for biofilm degradation and modulation of immune response to cancer) SUBMITTED Investigador
2020 - Atual	Struct4Dis: Applied Cellular Structural Biology: Molecular Views into Cell Function in Disease SUBMITTED Investigador
2018 - 2021	GLYCOInteract: Glycan-human microbiome interaction: glycan diversity and recognition in the human gut with impact on health and nutrition PTDC/BIA-MIB/31730/2017 Investigador REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal	Fundação para a Ciência e a Tecnologia
2018 - 2021	Characterization of reflectin proteins and reflectin-materials PTDC/BII-BIO/28878/2017 Investigador	Fundação para a Ciência e a Tecnologia
2018 - 2021	Destoxificação de peróxido de hidrogénio por Bactérias Patogénicas - Peroxidase tri-hémicas de E.coli como modelo PTDC/BBB-BQB/29442/2017 Investigador REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal	Fundação para a Ciência e a Tecnologia
2016 - 2019/05/01	An integrative structural biology approach to characterise the protein-carbohydrate microbial recognition Provided by PTCRIS: 139494 Investigador responsável	Ministério da Ciência Tecnologia e Ensino Superior
2016 - 2018/12	Molecular determinants of bacterial cellulosome diversity in different ecological niches Provided by PTCRIS: 144587 Investigador	Ministério da Ciência Tecnologia e Ensino Superior
2015 - 2018/11	Targeting p53 family proteins: on the route to new anticancer agents Provided by PTCRIS: 140607 Investigador	Ministério da Ciência Tecnologia e Ensino Superior
2013 - 2016/06	Modern Structural Biology: Resources for the advancement of in-house X-ray Crystallography 125363 Provided by PTCRIS: 125363 Investigador responsável	Ministério da Ciência Tecnologia e Ensino Superior
2013 - 2015/04	Ionic liquid-based systems for protein crystallization 129159 Provided by PTCRIS: 129159 Investigador	Ministério da Ciência Tecnologia e Ensino Superior
2011 - 2014/08	A carbohydrate microarray platform for discovery of ligands in polysaccharides recognised by microbial carbohydrate-binding modules. Provided by PTCRIS: 112537 112537 Investigador	Ministério da Ciência Tecnologia e Ensino Superior
2013 - 2014/06	Development of cohesin- microarrays for determining cohesin-dockerin specificities of novel cellulolytic species Provided by PTCRIS: 126085 126085 Investigador	Ministério da Ciência Tecnologia e Ensino Superior
2010 - 2013/06	The Cellulosome assembly: structure, function and specificity of new cellulases and supramolecular complexes Provided by PTCRIS: 100359 100359 Investigador responsável	Ministério da Ciência Tecnologia e Ensino Superior
2009 - 2011/12	Structure and function of novel carbohydrate-binding modules and cohesin-dockerin protein complexes from Clostridium thermocellum 69732 Provided by PTCRIS: 69732 Investigador	Ministério da Ciência Tecnologia e Ensino Superior
2008 - 2011/09	A combined approach of X-ray Crystallography, NMR and Computational Chemistry for the study of the molecular interactions that define the ligand specificity in cellulosomal Carbohydrate Binding Modules 68286 Provided by PTCRIS: 68286 Investigador responsável	Ministério da Ciência Tecnologia e Ensino Superior
2007 - 2009/04	Molecular determinants of ligand specificity in carbohydrate-binding modules and cohesin-dockerin complexes 82210 Provided by PTCRIS: 82210 Investigador	Ministério da Ciência Tecnologia e Ensino Superior
2007 - 2008/11	Structural and Functional Characterization of Nitrate Reductases and Formate Dehydrogenases 82151 Provided by PTCRIS: 82151 Investigador	Ministério da Ciência Tecnologia e Ensino Superior

Produções

Publicações

Artigo em revista

Carvalho, Ana Luísa. 2020. "SLMP53-1 interacts with wild-type and mutant p53 DNA-binding domain and reactivates multiple hotspot mutations". Biochimica et Biophysica Acta (BBA) - General Subjects 1864 (1): 129440-129440.
https://doi.org/10.1016/j.bbagen.2019.129440
Carvalho, Ana Luísa. 2019. "Molecular basis for the preferential recognition of ß1,3-1,4-glucans by the family 11 carbohydrate-binding module from Clostridium thermocellum". The FEBS Journal.
10.1111/febs.15162
Peixoto, Daniela; Malta, Gabriela; Cruz, Hugo; Barroso, Sónia; Carvalho, Ana Luisa; Ferreira, Luisa Maria; Branco, Paula Serio. 2019. "N-Heterocyclic olefin catalysis for the ring opening of cyclic amidine compounds: a pathway to the synthesis of e-caprolactam and ¿-lactam-derived amines". The Journal of Organic Chemistry.
No prelo • 10.1021/acs.joc.8b02823
Pedro Bule; Virgínia M. R. Pires; Victor D. Alves; Ana Luísa Carvalho; José A. M. Prates; Luís M. A. Ferreira; Steven P. Smith; et al. 2018. "Higher order scaffoldin assembly in Ruminococcus flavefaciens cellulosome is coordinated by a discrete cohesin-dockerin interaction". Scientific Reports.
10.1038/s41598-018-25171-8
Sabrina Santarsia; Ana Sofia Grosso; Filipa Trovão; Jesús Jiménez-Barbero; Ana Luísa Carvalho; Cristina Nativi; Filipa Marcelo. 2018. "Molecular recognition of a Thomsen-Friedenreich antigen mimetic targeting human galectin-3". ChemMedChem.
10.1002/cmdc.201800525
Krishan Kumar; Márcia A. S. Correia; Virgínia M R Pires; Arun Dhillon; Kedar Sharma; Vikky Rajulapati; Carlos M G A Fontes; Ana Luísa Carvalho; Arun Goyal. 2018. "Novel insights into the degradation of ß-1,3-glucans by the cellulosome of Clostridium thermocellum revealed by structure and function studies of a family 81 glycoside hydrolase". International Journal Of Biological Macromolecules 117: 890-901.
10.1016/j.ijbiomac.2018.06.003
Peixoto, Daniela; Figueiredo, Margarida; Malta, Gabriela; Roma-Rodrigues, Catarina; Baptista, Pedro V.; Fernandes, Alexandra R.; Barroso, Sónia; et al. 2018. "Synthesis, Cytotoxicity Evaluation in Human Cell Lines and in Vitro DNA Interaction of a Hetero-Arylidene-9(10H )-Anthrone". European Journal of Organic Chemistry 2018 (4): 545-549.
10.1002/ejoc.201701500
Gomes, A. S.; Trovao, F.; Pinheiro, B. A.; Freire, F.; Gomes, S.; Oliveira, C.; Domingues, L.; et al. 2018. "The Crystal Structure of the R280K Mutant of Human p53 Explains the Loss of DNA Binding". International Journal of Molecular Sciences 19 (4): 12-12.
10.3390/ijms19041184
Kryshtafovych, A.; Albrecht, R.; Basle, A.; Bule, P.; Caputo, A. T.; Carvalho, A. L.; Chao, K. L.; et al. 2018. "Target highlights from the first post-PSI CASP experiment (CASP12, May-August 2016)". Proteins-Structure Function and Bioinformatics 86: 27-50.
10.1002/prot.25392
Pedro Bule; Victor D. Alves; Vered Israeli-Ruimy; Ana L. Carvalho; Luís M. A. Ferreira; Steven P. Smith; Harry J. Gilbert; et al. 2017. "Assembly of Ruminococcus flavefaciens cellulosome revealed by structures of two cohesin-dockerin complexes". Scientific Reports.
10.1038/s41598-017-00919-w
Mariella Polino; Ana Luísa Carvalho; Lina Juknaite; Carla A.M. Portugal; Isabel Coelhoso; Maria João Romão; João Crespo. 2017. "Ion-Exchange Membranes for Stable Derivatization of Protein Crystals". Crystal Growth and Design 17 (9): 4563-4572.
10.1021/acs.cgd.7b00315
Virgínia M R Pires; Pedro M. Pereira; Joana L A Brás; Márcia A. S. Correia; Vânia Cardoso; Pedro Bule; Victor D Alves; et al. 2017. "Stability and Ligand Promiscuity of Type A Carbohydrate-binding Modules Are Illustrated by the Structure of Spirochaeta thermophila StCBM64C". Journal of Biological Chemistry 292 (12): 4847-4860.
10.1074/jbc.M116.767541
Magdalena Kowacz; Mateusz Marchel; Lina Juknaité; J. M. S. S. Esperança; Maria João Romão; Ana Luísa Carvalho; Luis Paulo Rebelo. 2017. "Infrared light-induced protein crystallization. Structuring of protein interfacial water and periodic self-assembly". Journal Of Crystal Growth 457: 362-368.
10.1016/j.jcrysgro.2016.01.003
dos Santos, Raquel; Carvalho, Ana Luisa; Roque, A. Cecilia A.. 2017. "Renaissance of protein crystallization and precipitation in biopharmaceuticals purification". Biotechnology Advances 35 (1): 41-50.
10.1016/j.biotechadv.2016.11.005
Hussain, A.; Semeano, A. T. S.; Palma, Sicj; Pina, A. S.; Almeida, J.; Medrado, B. F.; Padua, Accs; et al. 2017. "Tunable Gas Sensing Gels by Cooperative Assembly". Advanced Functional Materials 27 (27): 9-9.
10.1002/adfm.201700803
Joana L. A. Brás; Benedita Pinheiro; Kate Cameron; Fiona Cuskin; Aldino Viegas; Shabir Najmudin; Pedro Bule; et al. 2016. "Diverse specificity of cellulosome attachment to the bacterial cell surface". Scientific Reports 6: 38292-38292. https://research.unl.pt/en/publications/diverse-specificity-of-cellulosome-attachment-to-the-bacterial-cell-surface(74845819-6728-4765-8e52-ea72c70e9af4).html.
10.1038/srep38292
Magdalena Kowacz; M. Marchel; Lina Juknaité; J. M. S. S. Esperança; Maria João Romão; Ana Luísa Carvalho; Luis Paulo Rebelo. 2015. "Ionic-Liquid-Functionalized Mineral Particles for Protein Crystallization". Crystal Growth & Design 15 (6): 2994-3003.
10.1021/acs.cgd.5b00403
Maria Angelina de Sá Palma; Yan Liu; Hongtao Zhang; Yibing Zhang; Barry V McCleary; Guangli Yu; Qilin Huang; et al. 2015. "Unravelling glucan recognition systems by glycome microarrays using the designer approach and mass spectrometry". Molecular & Cellular Proteomics 14 (4): 974-988.
10.1074/mcp.M115.048272
Ribeiro, D.; Kulakova, A.; Quaresma, P.; Pereira, E.; Bonifacio, C.; Romao, M. J.; Franco, R.; Carvalho, A. L.. 2014. "Use of Gold Nanoparticles as Additives in Protein Crystallization". Crystal Growth & Design 14 (1): 222-227.
10.1021/cg4014398
Viegas, Aldino; Sardinha, Joao; Freire, Filipe; Duarte, Daniel F.; Carvalho, Ana L.; Fontes, Carlos M. G. A.; Romao, Maria J.; et al. 2013. "Solution structure, dynamics and binding studies of a family 11 carbohydrate-binding module from Clostridium thermocellum (CtCBM11)". The Biochemical journal 451 (2): 289-300. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=MEDLINE&KeyUT=MEDLINE:23356867&KeyUID=MEDLINE:23356867.
10.1042/bj20120627
Ana Luísa Carvalho; Maria João Romão; Luis Paulo Rebelo; Magdalena Kowacz; J. M. S. S. Esperança. 2012. "Hofmeister effects of ionic liquids in protein crystallization: Direct and water-mediated interactions". CrystEngComm 14 (15): 4912-4921. https://research.unl.pt/en/publications/hofmeister-effects-of-ionic-liquids-in-protein-crystallization-direct-and-watermediated-interactions(eb630e57-d88e-45a4-a34d-28bcde651aad).html.
10.1039/c2ce25129a
Pinheiro, B. A.; Bras, J. L. A.; Najmudin, S.; Carvalho, A. L.; Ferreira, L. M. A.; Prates, J. A. M.; Fontes, Cmga. 2012. "Flexibility and specificity of the cohesin-dockerin interaction: implications for cellulosome assembly and functionality". Biocatalysis and Biotransformation 30 (3): 309-315. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000304750500005&KeyUID=WOS:000304750500005.
10.3109/10242422.2012.681854
Bras, Joana L. A.; Alves, Victor D.; Carvalho, Ana Luisa; Najmudin, Shabir; Prates, Jose A. M.; Ferreira, Luis M. A.; Bolam, David N.; et al. 2012. "Novel Clostridium thermocellum Type I Cohesin-Dockerin Complexes Reveal a Single Binding Mode". The Journal of biological chemistry 287 (53): 44394-405. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=MEDLINE&KeyUT=MEDLINE:23118225&KeyUID=MEDLINE:23118225.
10.1074/jbc.M112.407700
Bras, J. L. A.; Cartmell, A.; Carvalho, A. L. M.; Verze, G.; Bayer, E. A.; Vazana, Y.; Correia, M. A. S.; et al. 2011. "Structural insights into a unique cellulase fold and mechanism of cellulose hydrolysis". Proceedings of the National Academy of Sciences of the United States of America 108 (13): 5237-5242. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000288894800024&KeyUID=WOS:000288894800024.
10.1073/pnas.1015006108
Garcia-Alvarez, Begona; Melero, Roberto; Dias, Fernando M. V.; Prates, Jose A. M.; Fontes, Carlos M. G. A.; Smith, Steven P.; Romao, Maria Joao; Carvalho, Ana Luisa; Llorca, Oscar. 2011. "Molecular Architecture and Structural Transitions of a Clostridium thermocellum Mini-Cellulosome". Journal of Molecular Biology 407 (4): 571-580. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000288925200008&KeyUID=WOS:000288925200008.
10.1016/j.jmb.2011.01.060
Ana Luísa Carvalho; Natália de Fátima Teixeira Correia; Maria João Romão; DQ Group Author. 2009. "Real-Time Monitoring of Molecular Dynamics of Ethylene Glycol Dimethacrylate Glass Former". Journal Of Physical Chemistry B 113 (43): 14209-14217. https://research.unl.pt/en/publications/realtime-monitoring-of-molecular-dynamics-of-ethylene-glycol-dimethacrylate-glass-former(fe8e55a5-aafd-4a2b-a60f-93347de9f37b).html.
10.1021/jp903212g
Freire, F.; Romão, M.J.; MacEdo, A.L.; Aveiro, S.S.; Goodfellow, B.J.; Carvalho, A.L.. 2009. "Preliminary structural characterization of human SOUL, a haem-binding protein". Acta Crystallographica Section F: Structural Biology and Crystallization Communications 65 (7): 723-726. http://www.scopus.com/inward/record.url?eid=2-s2.0-68149089746&partnerID=MN8TOARS.
10.1107/S174430910902291X
Godinho, M. H.; Filip, D.; Costa, I.; Carvalho, A. -L.; Figueirinhas, J. L.; Terentjev, E. M.. 2009. "Liquid crystalline cellulose derivative elastomer films under uniaxial strain". Cellulose 16 (2): 199-205. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000263352900005&KeyUID=WOS:000263352900005.
10.1007/s10570-008-9258-9
Anjos L. Macedo; Ana Luísa Carvalho; Eurico J Cabrita; Maria João Romão. 2008. "Molecular determinants of ligand specificity in family 11 carbohydrate binding modules - an NMR, X-ray crystallography and computational chemistry approach". Febs Journal 275 (10): 2524-2535. https://research.unl.pt/en/publications/molecular-determinants-of-ligand-specificity-in-family-11-carbohydrate-binding-modules--an-nmr-xray-crystallography-and-computational-chemistry-approach(1838ef96-4228-4380-9965-a5a64661ab85).html.
10.1111/j.1742-4658.2008.06401.x
José Pedro da Silva Trincão; José J. G. Moura; Pablo Javier Gonzalez; Ana Luísa Carvalho; Isabel Maria Andrade Martins Galhardas de Moura; Maria João Romão. 2007. "Heterodimeric nitrate reductase (NapAB) from Cupriavidus necator H16: purification, crystallization and preliminary X-ray analysis". Acta Crystallographica Section F-Structural Biology And Crystallization Com 63 (NA): 516-519. https://research.unl.pt/en/publications/heterodimeric-nitrate-reductase-napab-from-cupriavidus-necator-h16-purification-crystallization-and-preliminary-xray-analysis(d36d0822-7f80-4415-b022-3a4f09c10733).html.
10.1107/S1744309107022129
Carvalho, Ana Luisa; Dias, Fernando M. V.; Nagy, Tibor; Prates, Jose A. M.; Proctor, Mark R.; Smith, Nicola; Bayer, Edward A.; et al. 2007. "Evidence for a dual binding mode of dockerin modules to cohesins". Proceedings of the National Academy of Sciences of the United States of America 104 (9): 3089-3094. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000244661400015&KeyUID=WOS:000244661400015.
10.1073/pnas.0611173104
Santos-Silva, T.; Trincão, J.; Carvalho, A.L.; Bonifácio, C.; Auchère, F.; Raleiras, P.; Moura, I.; Moura, J.J.G.; Romão, M.J.. 2006. "The first crystal structure of class III superoxide reductase from Treponema pallidum". Journal of Biological Inorganic Chemistry 11 (5): 548-558. http://www.scopus.com/inward/record.url?eid=2-s2.0-33745364810&partnerID=MN8TOARS.
10.1007/s00775-006-0104-y
Najmudin, S; Guerreiro, CIPD; Carvalho, AL; Prates, JAM; Correia, MAS; Alves, VD; Ferreira, LMA; et al. 2006. "Xyloglucan is recognized by carbohydrate-binding modules that interact with beta-glucan chains". Journal of Biological Chemistry 281 (13): 8815-8828. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000236247100061&KeyUID=WOS:000236247100061.
10.1074/jbc.M510559200
Santos-Silva, T.; Trincão, J.; Carvalho, A.L.; Bonifácio, C.; Auchère, F.; Moura, I.; Moura, J.J.G.; Romão, M.J.. 2005. "Superoxide reductase from the syphilis spirochete Treponema pallidum: Crystallization and structure determination using soft X-rays". Acta Crystallographica Section F: Structural Biology and Crystallization Communications 61 (11): 967-970. http://www.scopus.com/inward/record.url?eid=2-s2.0-33744487895&partnerID=MN8TOARS.
10.1107/S174430910502885X
Carvalho, A.L.; Pires, V.M.R.; Gloster, T.M.; Turkenburg, J.P.; Prates, J.A.M.; Ferreira, L.M.A.; Romão, M.J.; et al. 2005. "Insights into the structural determinants of cohesin - Dockerin specificity revealed by the crystal structure of the type II cohesin from Clostridium thermocellum SdbA". Journal of Molecular Biology 349 (5): 909-915. http://www.scopus.com/inward/record.url?eid=2-s2.0-20344372400&partnerID=MN8TOARS.
10.1016/j.jmb.2005.04.037
Carvalho, AL; Goyal, A; Prates, JAM; Bolam, DN; Gilbert, HJ; Pires, VMR; Ferreira, LMA; et al. 2004. "The family 11 carbohydrate-binding module of Clostridium thermocellum Lic26A-Cel5E accommodates beta-1,4- and beta-1,3-1,4-mixed linked glucans at a single binding site". Journal of Biological Chemistry 279 (33): 34785-34793. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000223134800086&KeyUID=WOS:000223134800086.
10.1074/jbc.M405867200
Carvalho, AL; Dias, FMV; Prates, JAM; Nagy, T; Gilbert, HJ; Davies, GJ; Ferreira, LMA; Romao, MJ; Fontes, CMGA. 2003. "Cellulosome assembly revealed by the crystal structure of the cohesin-dockerin complex". Proceedings of the National Academy of Sciences of the United States of America 100 (24): 13809-13814. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000186803800015&KeyUID=WOS:000186803800015.
10.1073/pnas.1936124100
Carvalho, AL; Sanz, L; Barettino, D; Romero, A; Calvete, JJ; Romao, MJ. 2002. "Crystal structure of a prostate kallikrein isolated from stallion seminal plasma: A homologue of human PSA". Journal of Molecular Biology 322 (2): 325-337. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000178230500007&KeyUID=WOS:000178230500007.
10.1016/S0022-2836(02)00705-2
Carvalho, A. L.; Dias, J. M.; Sanz, L.; Romero, A.; Calvete, J. J.; Romao, M. J.; Carvalho, A.L.; et al. 2001. "Purification, crystallization and identification by X-ray analysis of a prostate kallikrein from horse seminal plasma". Acta Crystallographica Section D-Biological Crystallography 57 (8): 1180-1183. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000170041200025&KeyUID=WOS:000170041200025.
10.1107/s0907444901009805
Archer, M; Carvalho, AL; Teixeira, S; Moura, I; Moura, JJG; Rusnak, F; Romao, MJ. 1999. "Structural studies by X-ray diffraction on metal substituted desulforedoxin, a rubredoxin-type protein". Protein Science 8 (7): 1536-1545. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000081271700019&KeyUID=WOS:000081271700019.
10.1110/ps.8.7.1536
Teixeira, S.; Dias, J. M.; Carvalho, A. L.; Bourenkov, G.; Bartunik, H.; Almendra, M. J.; Moura, I.; Moura, J. J. G.; Romao, M. J.. 1999. "Crystallographic studies on a tungsten-containning formate dehydrogenase from Desulfovibrio gigas". Journal of Inorganic Biochemistry 74 (1-4): 89-89. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000081157700167&KeyUID=WOS:000081157700167.
Romero, A.; Romao, M. J.; Varela, P. F.; Kolln, I.; Dias, J. M.; Carvalho, A. L.; Sanz, L.; TopferPetersen, E.; Calvete, J. J.. 1997. "The crystal structures of two spermadhesins reveal the CUB domain fold". Nature Structural Biology 4 (10): 783-788. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:A1997YA20300007&KeyUID=WOS:A1997YA20300007.
10.1038/nsb1097-783
Romao, M. J.; Kolln, I.; Dias, J. M.; Carvalho, A. L.; Romero, A.; Varela, P. F.; Sanz, L.; Topfer-Petersen, E.; Calvete, J. J.. 1997. "Crystal structure of acidic seminal fluid protein (aSFP) at 1.9 angstrom resolution: a bovine polypeptide of the spermadhesin family". Journal of Molecular Biology 274 (4): 650-660. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000071252400018&KeyUID=WOS:000071252400018.
10.1006/jmbi.1997.1423
Dias, J. M.; Carvalho, A. L.; Kolln, I.; Calvete, J. J.; TopferPetersen, E.; Varela, P. F.; Romero, A.; Urbanke, C.; Romao, M. J.. 1997. "Crystallization and preliminary x-ray diffraction studies of aSFP, a bovine seminal plasma protein with a single CUB domain architecture". Protein Science 6 (3): 725-727. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:A1997WM74000023&KeyUID=WOS:A1997WM74000023.
10.1002/pro.5560060323

Capítulo de livro

Carvalho, Ana Luísa. 2019. "Resistance to Aminoglycosides". 1-38. John Wiley & Sons, Ltd.
10.1002/9781119282549.ch1
Ribeiro, Diana O.; Pinheiro, Benedita A.; Carvalho, Ana Luísa; Palma, Angelina S.. 2018. "Targeting protein-carbohydrate interactions in plant cell-wall biodegradation: the power of carbohydrate microarrays".
10.1039/9781788010641-00159
Carvalho, Ana Luisa; Santos-Silva, Teresa; Romao, Maria Joao; Cabrita, Eurico J.; Marcelo, Filipa. 2018. "Structural Elucidation of Macromolecules". In Essential Techniques for Medical and Life Scientists: A Guide to Contemporary Methods and Current Applications with the Protocols, 30-91. BENTHAM SCIENCE PUBLISHERS.
10.2174/9781681087092118010005
Brás, Joana L.A.; Carvalho, Ana Luisa; Viegas, Aldino; Najmudin, Shabir; Alves, Victor D.; Prates, José A.M.; Ferreira, Luís M.A.; et al. 2012. "Escherichia coli Expression, Purification, Crystallization, and Structure Determination of Bacterial Cohesin–Dockerin Complexes". In Methods in Enzymology, 395-415. Elsevier.
10.1016/b978-0-12-415931-0.00021-5
Carvalho, Ana Luisa; Trincao, Jose; Romao, Maria Joao. 2010. "X-ray crystallography in drug discovery". In Methods in molecular biology (Clifton, N.J.), 31-56.
Publicado

Outros

Conjunto de dados

My structures in the PDB. Up to Feb2020, I have co-authored 42 entries in the Protein Data Bank.. https://docentes.fct.unl.pt/almc/links/structures-protein-data-bank.

Atividades

Apresentação oral de trabalho

	Título da apresentação	Nome do evento Anfitrião (Local do evento)
2019/09/04	Investigating the ligand-specificity of a Carbohydrate-Binding protein Module from Clostridium thermocellum: a biotechnological tool to target ß1,3-1,4-mixed-linked glucans	GLUPOR13 Universidade do Porto, i3S (Porto, Portugal)
2019/01/09	X-Ray Crystallography in Drug Development: the case study of Galectin-3 and the Thomsen-Friedenreich Antigen Mimetic	Seminar of the I3DU PhD Program Universidade de Lisboa, Faculdade de Farmácia
2018/06/22	Investigating the carbohydrate preferences of cellulolytic bacteria	6th International Iberian Biophysics Congress University Jaume I, Castellón (Espanha)
2017/07/26	X-Ray Crystallography to investigate molecular interactions: seeing is believing	Ist Symposium of the Biomolecular Engineering Lab Biomolecular Engineering Lab, FCT-NOVA
2017/07/17	Integrative Structural Biology tools for the study of protein-ligand interactions	PCISBIO Day ITQB-NOVA
2014/08/10	The use of Gold Nanoparticles as Additives in Protein Crystallization	IUCr Meeting (Montreal, Canadá)
2014/07/17	Protein-ligand interactions investigated using X-Rays and Glycoarrays	PCISBIO Day ITQB-NOVA
2011/01/14	A structural biology contribution to the understanding of bio-ethanol production	Encontro REQUIMTE (Highlights Ciência2010) REQUIMTE-FCT-NOVA
2010/07/27	Carbohydrate Binding Modules, a Driving Force behind Cellulose Recognition and Degradation in the Microbial World	Session for Young Scientists at IBIO2010, BIT’s 3rd Annual World Congress of Industrial Biotechnology (Dalian, China)
2010/07/04	A structural biology contribution to the understanding of bio-ethanol production	Ciência2010 FCT-MCTES, Lisbon Congress Center (Lisbon)
2010/03/31	Protein-protein interactions determine the assembly of cellulosomes in Clostridium thermocellum	Meeting Protein-Protein Interactions and Protein Folding FCT-NOVA
2009/03/19	The Cellulosome: a nano-machine for the degradation of cellulose	Conference cycle of Facolta' di Scienze - Università degli Studi di Verona Facolta' di Scienze - Università degli Studi di Verona (Verona, Itália)
2008/02/17	The Cellulosome from Clostridium thermocellum: Building the Puzzle	EMBO Practical course: Combination of electron microscopy and X-ray crystallography (Gif-sur-Ivette, França)
2007/01/29	My research activities and scientific achievements as member of the Associate Laboratory REQUIMTE	Sessões Científicas do Departamento de Química da FCT-UNL
2005/04/13	A estrutura do Cellulosoma: um mega-complexo de proteínas destinado à degradação da celulose – Um estudo por Cristalografia de Raios-X	XXIV Ciclo de Conferências do DQ, Departamento de Química da FCT-UNL
2004/01/09	Cellulosome assembly and the crystal structure of the Cohesin-Dockerin complex	3º meeting ReQuimTe FCT-NOVA
2003/09/19	Os Cristais de Proteína como Biocatalisadores	DQ seminars FCT-NOVA
2000/10/11	Protein Identification and Sequencing by Crystallography: The Crystal Structure of Horse Prostate Kallikrein at 1.42 Å resolution	IBValencia Seminars Instituto de Biomedicina de Valencia, Consejo Superior de Investigaciones Cientificas (Valencia, Espanha)
1999/04/07	Crystallographic studies on a Xanthine Oxidase purified from Rat Liver	DQ seminars FCT-NOVA

Orientação

	Título / Tema Papel desempenhado	Curso (Tipo) Instituição / Organização
2019/12/01 - Atual	Translating the human-microbiome molecular cross-talk using glycan microarray and structural biology strategies Ref: SFRH/BD/143494/2019 Coorientador de Filipa Grifo Trovão	Biochemistry (Doutoramento) Universidade Nova de Lisboa, Portugal
2019/09/01 - Atual	Carbohydrate-recognition in the Human Gut – Are Bacteria friends or foes? Coorientador	MSc in Biochemistry (Mestrado) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2016 - Atual	Deciphering the human-microbiome glyco-code: an integrative approach to uncover protein-glycan interactions in the gut environment Ref: PD/BD/135517/2018 Coorientador de Raquel Lopes Costa	Biociências Moleculares (Doutoramento) Universidade Nova de Lisboa, Portugal
2015 - Atual	Protein-carbohydrate recognition in polysaccharide biodegradation: characterization studies using carbohydrate microarrays and macromolecular crystallography Ref: SFRH/BD/100569/2014 Coorientador de Diana de Oliveira Ribeiro	Bioquímica (Doutoramento) Universidade Nova de Lisboa, Portugal
2015 - Atual	Deciphering carbohydrate:protein interactions in the Human Microbiome – A combined high-throughput and structural approach Ref: PD/BD/105727/2014 Coorientador de Viviana Correia	Biociências Moleculares (Doutoramento) Universidade Nova de Lisboa, Portugal
2015 - Atual	Novel strategies for antibody purification through crystallization Ref: PD/BD/105753/2014 Orientador de Raquel Santos	Biociências Moleculares (Doutoramento) Universidade Nova de Lisboa, Portugal
2018/02/01 - 2019/01/31	MSc Fellow hired under project PTDC/BBB-BEP/0869/2014 Orientador de Filipa Trovão	REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2017/02/01 - 2018/01/31	MSc Fellow hired under project PTDC/DTP-FTO/1981/2014 Orientador de Filipa Trovão	REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2017 - 2018	Post-Doctoral Fellow hired under project PTDC/BIA-MIC/5947/2012 Orientador de Benedita Pinheiro, PhD	REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2016 - 2017	Post-Doctoral Fellow hired under project PTDC/BBB-BEP/0869/2014 Orientador de Benedita Pinheiro, PhD	REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2015 - 2017	Ligand discovery and structural-functional analysis of proteins involved in plant cell wall degradation Coorientador de Raquel Costa	Bioquímica (Mestrado) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2015 - 2016	Post-Doctoral Fellow hired under project RECI/BBB-BEP/0124/2012 Orientador de Ramesh Pandian, PhD	REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2014 - 2015	Structural characterization of glyco-proteins from the envelope of HIV-2 virus Coorientador de Elizabeth Nelly Pires	Bioquímica (Mestrado) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2014 - 2015	Post-Doctoral Fellow hired under project PTDC/BBB-BEP/3058/2012 Orientador de Lina Juknaité, PhD	REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2014 - 2015	Post-Doctoral Fellow hired under project RECI/BBB-BEP/0124/2012 Orientador de Isabel Bento, PhD	REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2013 - 2014	Structural characterization of glyco-proteins from the envelope of HIV-2 virus Orientador de Tiago Mestre	Bioquímica (Iniciação científica) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2011 - 2012	Using gold nanoparticles in protein crystallography: Studies in crystal growth and derivatization Coorientador de Diana Ribeiro	Bioquímica (Mestrado) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2009 - 2012	Molecular determinants of ligand specificity in carbohydrate-binding modules: an NMR and X-ray crystallography integrated study Coorientador	Bioquímica (Doutoramento) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2007 - 2009	Structural characterization of an exocellulase from the Cellulosome of Clostridium thermocellum Coorientador de Genny Verzé	Biochemistry (Mestrado) Università degli Studi di Verona, Itália

Organização de evento

	Nome do evento Tipo de evento (Tipo de participação)	Instituição / Organização
2020/07/20 - 2020/07/25	ISBio2020: A joint Instruct-ERIC/COST Summer School on Integrative Structural Biology (2020/07/20 - 2020/07/25) Outro (Coorganizador)	REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2015/07/13 - 2015/07/19	ISBio2015: Integrative Structural Biology tools for the study of protein-ligand interactions (2015/07/13 - 2015/07/19) Outro (Coorganizador)	Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2014 - 2015	2014, International Year of Crystallography at FCT-NOVA (http://xtal.dq.fct.unl.pt/iycr2014), includes regular conferences by national and international speakers, a photo contest (Crystals & Symmetry in Art, Science and Life) and an exhibition, from April 2014 to July 2015. (2014 - 2015) Simpósio (Membro da Comissão Organizadora)	Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2014/10/06 - 2014/10/12	ISBio2014: Integrative Structural Biology tools for the study of protein-ligand interactions (2014/10/06 - 2014/10/12) Outro (Coorganizador)	Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2011 - 2011	2011, International Year of Chemistry at FCT-UNL (http://www.dq.fct.unl.pt/IYC2011). (2010 - 2011) Simpósio (Membro da Comissão Organizadora)	Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Júri de grau académico

	Tema Tipo de participação	Nome do candidato (Tipo de grau) Instituição / Organização
2018/10/30	Design and production of peptide-based scaffolds for bioengineering applications Arguente principal	Iana Lychko (Mestrado) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2015/12/09	Production of membrane histidine kinases and structural studies on Thiosulfate dehydrogenase Arguente principal	Alina Vitaliyivna Kulakova (Mestrado) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2015/06/12	Discovering novel Carbohydrate-Active Enzymes in the cellulosome of anaerobic bacteria Arguente principal	Vânia Ondina Pedro Fernandes (Doutoramento) Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
2014/12/17	Structural and functional studies of a high activity NiFeSe hydrogenase Arguente	Marta Franco Coimbra Marques (Doutoramento) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2013/06/11	Deficiência na Desidrogenase dos Ésteres de Acil-Coenzima A de Cadeia Média (MCAD): caracterização de nova formas mutantes Arguente principal	Joana Rita Luís Nunes (Mestrado) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2012/11/20	Structure and function relationships in novel cellulosomal enzymes and cohesin-dockerin complexes Arguente principal	Joana Luís Armada Brás (Doutoramento) Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
2012/09/21	Integrated study by NMR and X-Ray Crystallography on the analysis of the molecular interactions in Heme-Binding Proteins Vogal	Filipe Miguel dos Santos Freire (Doutoramento) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2012/05/28	Molecular determinants of ligand specificity in carbohydrate-binding modules: and NMR and X-ray Crystallography integrated study Orientador	Aldino José Martins Viegas (Doutoramento) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2011/11/29	Rational use of dietary enzymes and lipids to improve broiler performance and meat quality Vogal	Teresa Paula Costa Ribeiro (Doutoramento) Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
2010/10/08	Biochemical and structural studies on the PhoR-PhoB two component regulatory system from Deinococcus radiodurans Arguente	Sofia Maria Dias de Gouveia Caria (Doutoramento) Universidade de Lisboa Faculdade de Farmácia, Portugal
2010/02/08	Novel insight into the mechanism of cellulosome assembly and plant cell wall hydrolysis in anaerobic bacteria Arguente principal	Benedita Andrade Pinheiro (Doutoramento) Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
2009/03/19	Expression and purification of human muscleblind-like-protein-1 and structural characterization of an exocellulase from Clostridium thermocellum Arguente principal	Genny Verzé (Mestrado)
2008/11/21	Structural studies on family III alcohol dehydrogenases from pathogenic bacteria Arguente	David Marçal (Doutoramento) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2007/07/25	Estrutura e função de hemicelulases e complexos coesina-doquerina: implicações na hidrólise de polissacáridos estruturais da parede celular vegetal Arguente principal	Fernando Manuel Vaz Dias (Doutoramento) Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
2006/11/13	Structural Characterization of Heme and Non-Heme Iron-Containing Proteins Vogal	Teresa Sacadura Santos Silva (Doutoramento) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Consultoria / Parecer

	Descrição da atividade	Instituição / Organização
2014 - Atual	Web design, feed and maintenance of websites (http://sites.fct.unl.pt/xtal, https://sites.fct.unl.pt/pcisbio/, http://xtal.dq.fct.unl.pt/iycr2014, https://www.facebook.com/XtalNOVA, https://eventos.fct.unl.pt/isbio)	Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2005 - Atual	Peer-reviewing in international journals: Acta Crystallographica Section F, Crystals, Journal of Biological Inorganic Chemistry, Chemical Physics Letters, Journal of Applied Crystallography, Journal of Crystal Growth https://publons.com/researcher/1327109/ana-luisa-carvalho/peer-review/
2006 - 2012	Translation activities to Journal Science in School (http://www.scienceinschool.org/). I contribute to this project by translating to Portuguese several articles that I find of interest to young students. After translation, the articles are made available online.

Curso / Disciplina lecionado

	Disciplina	Curso (Tipo)	Instituição / Organização
2007 - Atual	Support, on an yearly basis, to the Disciplines Fundamentos de Bioquímica Estrutural (undergraduate) e Bioquímica Estrutural (MSc students)	(Mestrado)	Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2018/07/18 - 2018/07/19	Workshop Cristalografia de Raios-X, 18-19 July, UCIBIO-FCT-NOVA	(Outros)	Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2015/07/13 - 2015/07/19	Co-organizer of International hands-on Course ISBio2015: Integrative Structural Biology tools for the study of protein-ligand interactions, 13-19 Julho, DQ-FCT-NOVA. INSTRUCT/COST supported training course	(Outros)
2014/10/06 - 2014/10/12	Co-organizer of international hands-on Course ISBio2014: Integrative Structural Biology tools for the study of protein-ligand interactions, 6-12 October, DQ-FCT-NOVA. INSTRUCT/COST supported training course	(Outros)
2012/07/11 - 2012/07/24	Summer Course 2012: Hands-On Course in Proteins and Proteomics, 11-24 July, FCT-UNL (co-organization and teaching in the X-ray Crystallography module).	(Outros)	Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2010/07/11 - 2010/07/24	Summer Course 2010: Hands-On Course in Proteins and Proteomics, 11-24 July, FCT-UNL (co-organization and teaching in the X-ray Crystallography module).	(Outros)	Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2010/02/01 - 2010/02/05	REQUIMTE Advanced Course 2010: Protein Crystallography, 1-5 February, FCT-UNL (co-organization and teaching).	(Outros)	REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2009/07/07 - 2009/09/18	Summer Course 2009: Hands-On Course in Proteins and Proteomics, 7-18 September, FCT-UNL (co-organization and teaching; supervisor of the X-ray Crystallography module).	(Outros)	Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2008/07/12 - 2008/07/25	Summer Course 2008: Hands-On Course in Proteins and Proteomics, 12-25 July, FCT-UNL (co-organization and teaching; supervisor of the X-ray Crystallography module).	(Outros)	Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2000 - 2007	Curso Monográfico editions: 2007, 2004, 2001, 2000: Cristalografia de Proteínas, FCT-NOVA (co-organization and teaching).	(Outros)	Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Entrevista / Programa (rádio / tv)

	Programa	Tema
2010 - 2010	Encontro Ciência2010; Session "Bio-Energia e Biocombustíveis".	A structural biology contribution to the understanding of bio-ethanol production
2002 - 2002	Antena 1	PhD thesis subject

Membro de associação

	Nome da associação	Tipo de participação
2016 - Atual	Sociedade Portuguesa de Química
1998 - Atual	Sociedade Portuguesa Biofísica

Membro de comissão

	Descrição da atividade Tipo de participação	Instituição / Organização
2012 - 2014	Substitute Evacuation Coordinator of the Internal Emergency Plan of the TOMO 3 - Edifício Departamental (Chemistry wing) Outro	Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Distinções

Prémio

2018	IUCr Young Scientist Award, ECM31 in Oviedo, Spain (attributed to PhD student Raquel Santos)
2016	Best poster award at GlycoSummerSchool, Groningen, Alemanha (attributed to PhD student Viviana Correia)
2015	Best poster award at GLUPOR11 (attributed to PhD student Diana Ribeiro)
2014	Best poster award at 3rd ENURS & ESRF Day (attributed to post-graduate student Viviana Correia) Instituto Politécnico de Leiria, Portugal
2014	Best poster award at 1st FEBS-INSTRUCT Crystallization Course: Advanced methods in macromolecular crystallization VI, Nové Hrady, Czech Republic (attributed to PhD student Diana Ribeiro)
2013	Scientific Merit Prize Santander-Totta/Universidade Nova de Lisboa Santander-Totta/Universidade Nova de Lisboa, Portugal
2013	Bluepharma / Universidade de Coimbra Innovation Award Bluepharma, Portugal
2013	António Xavier Prize awarded to my PhD student Aldino Viegas, for the Best National Thesis in the field of NMR Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2011	Best poster award at the 9th Congress Carbohydrate Bioengeneering Meeting (attributed to PhD student Aldino Viegas)
2006	2nd best poster presentation award at III Bienal of GERMN (attributed to PhD student Aldino Viegas)

Título

2010	Chair of the Session for Young Scientists at IBIO2010, BIT’s 3rd Annual World Congress of Industrial Biotechnology, 24-27 July, Dalian, People’s Republic of China

Outra distinção

2002	Post-doctoral scholarship SFRH/BPD/9446/2002 Fundação para a Ciência e a Tecnologia, Portugal
1998	PhD scholarship PRAXIS XXI/BD/15763/98 Fundação para a Ciência e a Tecnologia, Portugal
1996	MSc scholarship PRAXIS XXI/BM/7221/95 Fundação para a Ciência e a Tecnologia, Portugal