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Débora Ferreira (DF) is a Junior Researcher at Centre of Biological Engineering (CEB) - University of Minho (UM, Braga). She graduated in Biomedical Engineering from the Institute Polytechnique of Bragança (IPB, Bragança) in 2011. Two years later, she obtained a master's degree in Bioengineering from UM. During 2014, she worked on developing novel platforms for cancer diagnosis at a newly established biotech start-up, Inception - Life Sciences Research and Development, Ltd (Guimarães), where she gained experience in a highly challenging and innovative business environment. In 2015, she joined CEB, where her research was funded by the Lipid'NP'Phage project, focusing on engineering a novel platform for cancer therapy based on bacteriophage particles. In 2016, she started her PhD in Bioengineering Systems under the MIT-Portugal Program. During this time, she was a visiting student at the Department of Cancer Biology in the University of Texas MD Anderson Cancer Center (United States), under the supervision of Professor Raghu Kalluri. She established several national collaborations including with International Iberian Nanotechnology Laboratory (INL, Braga), Life and Health Sciences Research Institute (ICVS, Braga) and Centre for Neuroscience and Cell Biology (CNC, Coimbra). She concluded her PhD in November 2021. That same year, she was awarded with an oncology research grant attributed by the Portuguese Cancer League. In 2022, she secured a Junior Researcher position (2022.01681.CEECIND). Currently, she is a member of the Biosystems group (www.ceb.uminho.pt/BIOSYSTEMS) and is involved in several projects. DF has published 23 peer-reviewed papers in international journals (8 as 1st author, plus 4 under review and 2 in preparation) with an h-index=12 and 580 citations; 4 book chapters and authored 53 communications (22 oral and 31 poster) in national and international conferences (presenting author in 12 posters and 13 orals, 2 of them invited). She has been responsible for the supervision of 1 PhD, 9 MSc, 1 BSc, 3 MSc curricular projects, and mentoring of 25 students (7 PhD and 17 MSc students), being actively implicated in international raising funds activities. DF serves as a reviewer for several international peer-reviewed journals. In addition, she is guest co-editing the special issue "Bio-Applications of engineered Escherichia coli" for Bioengineering (MDPI) for International Journal of Molecular Sciences (IJMS, MDPI). DF participated in several knowledge dissemination activities (CEB Open Day, Best Students at UM, European Researcher's Night, Pint of Science) and shared her research outcomes through newspaper/digital news (O Louzadense, ASPIC, MaisGuimarães, Porto Canal, Rádio Vizela). She has received 7 awards and/or honors. Additionally, she is member of several associations, including SPLC-CRS, PNEV, SNEV, EACR, ASPIC, among others.
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Identificação

Identificação pessoal

Nome completo
Débora Ferreira
Data de nascimento
1990/11/24
Género
Feminino

Nomes de citação

  • Ferreira, D.

Identificadores de autor

Ciência ID
1413-A87E-D7C9
ORCID iD
0000-0002-0937-4047
Researcher Id
T-1353-2017
Scopus Author Id
27567703100

Endereços de correio eletrónico

  • deboraferreira@ceb.uminho.pt (Profissional)

Telefones

Telefone
  • 253601970 (Profissional)

Moradas

  • Universidade do Minho, Campus de Gualtar, 4710-057, Braga, Braga, Portugal (Profissional)

Websites

Domínios de atuação

  • Ciências Médicas e da Saúde - Biotecnologia Médica - Diagnóstico e Terapias de Base Genética
  • Ciências da Engenharia e Tecnologias - Engenharia Médica - Engenharia Médica
  • Ciências Médicas e da Saúde - Biotecnologia Médica - Tecnologias que envolvem a Manipulação de Células,Tecidos,Órgãos ou todo o Organismo
  • Ciências Médicas e da Saúde - Biotecnologia Médica - Biotecnologia Aplicada à Saúde
  • Ciências Naturais - Ciências Biológicas - Biologia Molecular
  • Ciências da Engenharia e Tecnologias - Nanotecnologia
  • Ciências Naturais - Ciências Biológicas - Microbiologia

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2)
Espanhol; Castelhano Utilizador elementar (A2) Utilizador elementar (A2) Utilizador elementar (A1) Utilizador elementar (A2) Utilizador elementar (A1)
Francês Utilizador elementar (A2) Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1)
Formação
Grau Classificação
2016/10/01 - 2021/11/17
Concluído
 PhD Program in Bioengineering Systems - MIT Portugal Program (Doutoramento)
Universidade do Minho Escola de Engenharia, Portugal
"Peptide-mediated targeted delivery system towards triple negative breast cancer treatment" (TESE/DISSERTAÇÃO)
 Very good (maximum grade)
2020/01 - 2020/02
Concluído
 FELASA Accredited Course in Laboratory Animal Science (Outros)
Universidade do Minho Escola de Medicina, Portugal
 Approved
2011/09/01 - 2013/11/12
Concluído
 Master on Bioengineering (Mestrado)
Universidade do Minho Escola de Engenharia, Portugal
"Design of new strategies for breast cancer diagnosis" (TESE/DISSERTAÇÃO)
 16
2008/09/01 - 2011/09/01
Concluído
 Biomedical Engineering (Licenciatura)
Instituto Politécnico de Bragança, Portugal
"Construction of an inference system based on Fuzzy Logic paradigm to evaluate the fetal risk" (TESE/DISSERTAÇÃO)
 14
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2023/04 - Atual Investigador Contratado (Investigação) Universidade do Minho Centro de Engenharia Biológica, Portugal
Universidade do Minho, Portugal
2021/06/01 - 2022/05/31 Investigador (Investigação) Liga Portuguesa Contra o Cancro Núcleo Regional do Norte, Portugal
Universidade do Minho, Portugal
2015/04/01 - 2016/05/31 Investigador (Investigação) Universidade do Minho Centro de Engenharia Biológica, Portugal

Outros

Categoria Profissional
Instituição de acolhimento 		Empregador
2016/10/01 - 2021/11/17 PhD Student Universidade do Minho, Portugal
Universidade do Minho Centro de Engenharia Biológica, Portugal
2019/02 - 2019/08 Visiting PhD Student University of Texas MD Anderson Cancer Center, Estados Unidos
2013/12/31 - 2014/12/31 Trainee Researcher Inception Life Sciences R&D, Portugal
Projetos

Bolsa

Designação Financiadores
2021/06/01 - 2022/05/31 Engineered exosome-mimetic nanovesicles as drug delivery systems in triple negative breast cancer
Liga Portuguesa Contra o Cancro
Bolseiro de Pós-Doutoramento
Universidade do Minho Centro de Engenharia Biológica, Portugal
 Liga Portuguesa Contra o Cancro
Concluído
2020/12/02 - 2021/05/31 Development of alternative multivalent drug carriers towards triple negative breast cancer
CEB-BI-11-2020
Bolseiro de Doutoramento
Universidade do Minho Centro de Engenharia Biológica, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2016/05/01 - 2016/09/30 Development of (bio) molecules' cocktails (including (bio) polymers, enzymes and (bio) surfactants) to promote additional oil recovery
PARTEX_2016-2017
Bolseiro de Investigação
Universidade do Minho Centro de Engenharia Biológica, Portugal
 Partex Oil and Gas Holdings Corp
Concluído
2015/04/01 - 2015/09/30 Design of novel breast tumor 'targeted' multifunctional nanoparticles
PTDC/SAU-BMA/121028/2010
Bolseiro de Investigação
Universidade do Minho Centro de Engenharia Biológica, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído

Outro

Designação Financiadores
2025/01 - Atual Uncovering therapeutic vulnerabilities in anthracycline-resistant triple negative breast cancer
CEBIMF.2025A
Investigador responsável
Universidade do Minho Centro de Engenharia Biológica, Portugal
 Universidade do Minho Centro de Engenharia Biológica
Em curso
2023/04 - Atual Unravelling synthetic lethal interactions in chemo-resistant triple negative breast cancer cells using bio-inspired targeted nanovesicles
2022.01681.CEECIND
Investigador responsável
Universidade do Minho Centro de Engenharia Biológica, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2021/01/01 - Atual Associate Laboratory on Biotechnology, Bioengineering and microELectromechanical Systems
LA/P/0029/2020
Investigador
Universidade do Minho Centro de Engenharia Biológica, Portugal

Universidade do Minho Labbels, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2024/01 - 2024/11 ValBioDerm - Validation of prebiotic biosurfactants produced by lactic acid bacteria for dermic applications
ValBioDerm
Researcher
Universidade do Minho Centro de Engenharia Biológica, Portugal

Universidade de Vigo Escola de Enxeñería Industrial, Espanha
Concluído
2014/01/01 - 2015/09/30 Lipid NP Phage - Design of novel breast tumor 'targeted` multifunctional nanoparticles
PTDC/SAU-BMA/121028/2010
Bolseiro de Investigação
Universidade do Minho Centro de Engenharia Biológica, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2014/06 - 2015/06 Biotechnology and Bioengineering for the Quality of Life and Sustainable Development
NORTE-07-0124-FEDER-000027
Team member
Universidade do Minho Centro de Engenharia Biológica, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
Produções

Publicações

Artigo em conferência
  1. Couto, M. R.; Gudiña, E. J.; Ferreira, D.; Teixeira, J. A.; Rodrigues, L. R.; Soares, L. P.; Ribeiro, M. T.. "Characterization of a Biopolymer Produced by Arthrobacter viscosus CECT 908 for Application in Microbial Enhanced Oil Recovery". Trabalho apresentado em OGWA 2018 - Society of Petroleum Engineers - SPE EOR Conference at Oil and Gas West Asia 2018, Muscat, 2018.
    Publicado • 10.2118/190460-ms
Artigo em revista
  1. Sousa, A.M.; Ferreira, D.; Rodrigues, L.R.; Pereira, M.O.. "Aptamer-based therapy for fighting biofilm-associated infections". Journal of Controlled Release 367 (2024): 522-539. http://dx.doi.org/10.1016/j.jconrel.2024.01.061.
    Publicado • 10.1016/j.jconrel.2024.01.061
  2. Ferreira, D.; Santos-Pereira, C.; Costa, M.; Afonso, J; Yang, S.; Hensel, J.; McAndrews, K.M.; et al. "Exosomes modified with anti-MEK1 siRNA lead to an effective silencing of triple negative breast cancer cells". Biomaterials Advances 154 (2023): 213643. http://dx.doi.org/10.1016/j.bioadv.2023.213643.
    Publicado • 10.1016/j.bioadv.2023.213643
  3. Afonso, J.; Gonçalves, C.; Costa, M.; Ferreira, D.; Santos, L.; Longatto-Filho, A.; Baltazar, F.. "Glucose Metabolism Reprogramming in Bladder Cancer: Hexokinase 2 (HK2) as Prognostic Biomarker and Target for Bladder Cancer Therapy". Cancers 15 3 (2023): 982. http://dx.doi.org/10.3390/cancers15030982.
    Publicado • 10.3390/cancers15030982
  4. Sande, M.G.; Ferreira, D.; Rodrigues, J.L.; Melo, L.D.R.; Saragliadis, A.; Linke, D.; Moreira, F.T.C.; Sales, M.G.F.; Rodrigues, L.R.. "Aptasensor for the Detection of Moraxella catarrhalis Adhesin UspA2". Bioengineering 10 2 (2023): 178. http://dx.doi.org/10.3390/bioengineering10020178.
    Publicado • 10.3390/bioengineering10020178
  5. Andrade, R.G.D.; Ferreira, D.; Veloso, S.R.S.; Santos-Pereira, C.; Castanheira, E.M.S.; Côrte-Real, M.; Rodrigues, L.R.. "Synthesis and Cytotoxicity Assessment of Citrate-Coated Calcium and Manganese Ferrite Nanoparticles for Magnetic Hyperthermia". Pharmaceutics 14 12 (2022): 2694. http://dx.doi.org/10.3390/pharmaceutics14122694.
    Publicado • 10.3390/pharmaceutics14122694
  6. Santos-Pereira, C.; Guedes, J.P.; Ferreira, D.; Rodrigues, L.R.; Côrte-Real, M.. "Lactoferrin perturbs intracellular trafficking, disrupts cholesterol-rich lipid rafts and inhibits glycolysis of highly metastatic cancer cells harbouring plasmalemmal V-ATPase". International Journal of Biological Macromolecules 220 (2022): 1589-1604. http://dx.doi.org/10.1016/j.ijbiomac.2022.09.120.
    Publicado • 10.1016/j.ijbiomac.2022.09.120
  7. Silva, R.; Ferreira, D.; Rodrigues, L.R.. "Exosome-based delivery of RNAi leads to breast cancer inhibition". Journal of Drug Delivery Science and Technology (2022): https://doi.org/10.1016/j.jddst.2022.103931.
    Publicado • 10.1016/j.jddst.2022.103931
  8. Sande, M.G.; Roque, L.; Braga, A.; Marques, M.; Ferreira, D.; Saragliadis, A.; Rodrigues, J.L.; et al. "Design of new hydrolyzed collagen-modified magnetic nanoparticles to capture pathogens". J Biomed Mater Res (2022):
    Publicado • 10.1002/jbm.b.35155
  9. Sande, M.G.; Ferreira, D.; Rodrigues, J.L.; Melo, L.D.R.; Linke, D.; Silva, C.J.; Moreira, F.T.C.; Sales, M.G.F.; Rodrigues, L.R.. "Electrochemical Aptasensor for the Detection of the Key Virulence Factor YadA of Yersinia enterocolitica". Biosensors (2022): https://doi.org/10.3390/bios12080614.
    Publicado • 10.3390/bios12080614
  10. Ferreira, D.; Moreira, J.N.; Rodrigues, L.R.. "New advances in exosome-based targeted drug delivery systems". Critical Reviews in Oncology/Hematology 172 (2022): 103628. http://dx.doi.org/10.1016/j.critrevonc.2022.103628.
    Publicado • 10.1016/j.critrevonc.2022.103628
  11. Pereira, A.C.; Sousa, D.A.; Pina, A.; Ferreira, D.; Santos-Pereira, C.; Melo, L.D.R.; Sales, M.G.F.; Sousa, S.F.; Rodrigues, L.R.. "Identification of novel aptamers targeting Cathepsin B-overexpressing prostate cancer cells". Molecular Systems Design & Engineering (2022):
    Publicado • 10.1039/D2ME00022A
  12. Sousa, Diana A.; Carneiro, Mariana; Ferreira, Débora; Moreira, Felismina T. C.; Sales, Maria Goreti F. v; Rodrigues, Lígia R.. "Recent advances in the selection of cancer-specific aptamers for the development of biosensors". Current Medicinal Chemistry 29 (2022): http://dx.doi.org/10.2174/0929867329666220224155037.
    Publicado • 10.2174/0929867329666220224155037
  13. Sande, M.G.; Rodrigues, J.L.; Ferreira, D.; Silva, C.J.; Rodrigues,L.R.. "Novel Biorecognition Elements against Pathogens in the Design of State-of-the-Art Diagnostics". Biosensors (2021): https://doi.org/10.3390/bios11110418.
    Publicado • 10.3390/bios11110418
  14. Tsogtbaatar, K.; Sousa, D.A.; Ferreira, D.; Tevlek, A.; Aydin, H.M.; Çelik, E.; Rodrigues, L.R.. "In vitro selection of DNA aptamers against human osteosarcoma". Investigational New Drugs 40 1 (2021): 172-181. http://dx.doi.org/10.1007/s10637-021-01161-y.
    Publicado • 10.1007/s10637-021-01161-y
  15. Ferreira, D.; Barbosa, J.; Sousa, D.A.; Silva, C.; Melo, L.D.R.; Avci-Adali, M.; Wendel, H.P.; Rodrigues, L.R.. "Selection of aptamers against triple negative breast cancer cells using high throughput sequencing". Scientific Reports 11 1 (2021): http://dx.doi.org/10.1038/s41598-021-87998-y.
    Publicado • 10.1038/s41598-021-87998-y
  16. Pereira, A.C.; Ferreira, D.; Santos-Pereira, C.; Vieira, T.F.; Sousa, S.F.; Sales, G.; Rodrigues, L.R.. "Selection of a new peptide homing SK-BR-3 breast cancer cells". Chemical Biology & Drug Design 97 4 (2020): 893-903. http://dx.doi.org/10.1111/cbdd.13816.
    Publicado • 10.1111/cbdd.13816 (first author)
  17. Ferreira, D.; Silva, A.P.; Nobrega, F.L.; Martins, I.M.; Barbosa-Matos, C.; Granja, S.; Martins, S.F.; Baltazar, F.; Rodrigues, L.R.. "Rational Identification of a Colorectal Cancer Targeting Peptide through Phage Display.". Scientific reports (2019): https://doi.org/10.1038/s41598-019-40562-1.
    Publicado • 10.1038/s41598-019-40562-1
  18. Britto, K.; Francisco, C.; Ferreira, D.; Borges, B.; Conti, R.; Profeti, D.; Rodrigues, L.R.; et al. "Identifying New Isatin Derivatives with GSK-3ß Inhibition Capacity through Molecular Docking and Bioassays". Journal of the Brazilian Chemical Society (2019): http://dx.doi.org/10.21577/0103-5053.20190206.
    Publicado • 10.21577/0103-5053.20190206
  19. Couto, M.R.; Gudiña, E.J.; Ferreira, D.; Rodrigues, L.R.. "The biopolymer produced by Rhizobium viscosum CECT 908 is a promising agent for application in Microbial Enhanced Oil Recovery". New biotechnology (2018): https://doi.org/10.1016/j.nbt.2018.11.002.
    Publicado • 10.1016/j.nbt.2018.11.002
  20. Vecino, X.; Rodríguez-López, L.; Ferreira, D.; Cruz, J.M.; Moldes, A.B.; Rodrigues, L.R.. "Bioactivity of glycolipopeptide cell-bound biosurfactants against skin pathogens". International Journal of Biological Macromolecules 109 (2018): 971-979. https://doi.org/10.1016/j.ijbiomac.2017.11.088.
    Publicado • 10.1016/j.ijbiomac.2017.11.088
  21. Ferreira, A.; Vecino, X.; Ferreira, D.; Cruz, J.M.; Moldes, A.B.; Rodrigues, L.R.. "Novel cosmetic formulations containing a biosurfactant from Lactobacillus paracasei". Colloids and Surfaces B: Biointerfaces 155 (2017): 522-529. https://doi.org/10.1016/j.colsurfb.2017.04.026.
    Publicado • 10.1016/j.colsurfb.2017.04.026
  22. Silva, Vera L.; Ferreira, Debora; Nobrega, Franklin L.; Martins, Ivone M.; Kluskens, Leon D.; Rodrigues, Ligia R.. "Selection of Novel Peptides Homing the 4T1 CELL Line: Exploring Alternative Targets for Triple Negative Breast Cancer". PLOS ONE 11 8 (2016): e0161290. http://dx.doi.org/10.1371/journal.pone.0161290.
    Publicado • 10.1371/journal.pone.0161290 (first author)
  23. Nobrega, F.L.; Ferreira, D.; Martins, I.M.; Suarez-Diez, M.; Azeredo, J.; Kluskens, L.D.; Rodrigues, L.R.. "Screening and characterization of novel specific peptides targeting MDA-MB-231 claudin-low breast carcinoma by computer-aided phage display methodologies". BMC Cancer 16 1 (2016): https://doi.org/10.1186/s12885-016-2937-2.
    Publicado • 10.1186/s12885-016-2937-2
Capítulo de livro
  1. Ferreira, D.; Silva, R.; Figueiredo, L.; Rodrigues, L.R.. "Smart Targeted-Nanocarriers for Cancer Therapeutics". In Biogenic Nanomaterials for Environmental Sustainability: Principles, Practices, and Opportunities, 377-407. Springer International Publishing, 2024.
    Publicado • 10.1007/978-3-031-45956-6_15
  2. Sousa, D.; Ferreira, D.; Rodrigues, J.L.; Rodrigues, L. R.. "Nanotechnology in Targeted Drug Delivery and Therapeutics". In Applications of Targeted Nano Drugs and Delivery Systems, 357-409. Elsevier, 2019.
    Publicado • 10.1016/b978-0-12-814029-1.00014-4
  3. Ferreira, D.; Martins, I.M.. "Artificial virus particles". In Bioinspired Materials for Medical Applications. Elsevier, 2017.
    Publicado • 10.1016/B978-0-08-100741-9.00015-2
  4. Rodrigues, J.L.; Ferreira, D.; Rodrigues, L.R.. "Synthetic biology strategies towards the development of new bioinspired technologies for medical applications". In Bioinspired Materials for Medical Applications. Elsevier, 2017.
    Publicado • 10.1016/B978-0-08-100741-9.00016-4
Poster em conferência
  1. Ferreira, D.; Rodrigues, L.R.. "Engineering extracellular vesicles for enhanced cancer-targeted therapeutic cargo delivery". Trabalho apresentado em 5th Edition Next-Generation Synthetic Biology, 2024.
  2. Ferreira, D.; Rodrigues, L.R.. "Engineered extracellular vesicles for cancer-targeted therapy". Trabalho apresentado em 2nd Young Researchers day, 2024.
  3. Teixeira, S..; Ferreira, D.; Rodrigues, L.R.; Castanheira, E.M.S.; Carvalho, M.A.. "Nanoformulações de um novo composto muito promissor para terapia do cancro da mama triplo negativo". Trabalho apresentado em 6º Encontro Nacional de Jovens Investigadores em Oncologia - Liga Portuguesa Contra o Cancro Núcleo Regional do Norte, Portugal, 2024.
  4. Gonçalves, C.; Rodrigues, L.R.; Ferreira, D.. "Entrega de CRISPR-Cas9 mediada por vesículas extracelulares para o direcionamento do microRNA-155 em cancro da mama triplo negativo". Trabalho apresentado em 6º Encontro Nacional de Jovens Investigadores em Oncologia - Liga Portuguesa Contra o Cancro Núcleo Regional do Norte, Portugal, 2024.
  5. Pereira, A.C.; Santos-Pereira, C.; Ferreira, D.; Leite, B.; Dias, A.; Rodrigues, L.R.. "Derivados de purina: opções terapêuticas contra o cancro de mama triplo negativo". Trabalho apresentado em 6º Encontro Nacional de Jovens Investigadores em Oncologia - Liga Portuguesa Contra o Cancro Núcleo Regional do Norte, Portugal, 2024.
  6. Gonçalves, C.; Rodrigues, L. R.; Ferreira, Débora. "Exploring Exosome-Based CRISPR-Cas9 Delivery for MicroRNA-155 Targeting in Triple Negative Breast Cancer". Trabalho apresentado em Ciência 2024 - Encontro com a Ciência e Tecnologia em Portugal, 2024.
  7. Novo, I.; Santos-Pereira, C.; Rodrigues, L.R.; Ferreira, D.. "Targeted Protein Delivery: Lactoferrin-Loaded Exosomes for Enhanced Colorectal Cancer Therapy". Trabalho apresentado em Ciência 2024 - Encontro com a Ciência e Tecnologia em Portugal, 2024.
  8. Oliveira, S.; Ferreira, D.; Padrão, J.; Catarina, S.; Monteiro, F.; Zille, A.; Rodrigues, L.R.; et al. "Influence of therapeutic ultrasound on human chondrocytes to treat cartilage degeneration". Trabalho apresentado em LABBELS Meeting 2024, 2024.
  9. Novo, I.; Santos-Pereira, C.; Rodrigues, L.R.; Ferreira, D.. Autor correspondente: Ferreira, D.. "Exploring Lactoferrin-loaded Exosomes as a Novel Therapeutic Strategy for Colorectal Cancer". Trabalho apresentado em 6th meeting on medicinal biotechnology - School of Health of P.Porto, 2024.
  10. Gonçalves, C.; Rodrigues, L.R.; Ferreira, D.. Autor correspondente: Ferreira, D.. "Potential of exosome-mediated delivery of CRISPR-Cas9 for microRNA-155 targeting in triple negative breast cancer". Trabalho apresentado em 6th meeting on medicinal biotechnology - School of Health of P.Porto, 2024.
  11. Ferreira, D.; Rodrigues, L.R.. Autor correspondente: Ferreira, D.. "Implications of MEK 1 silencing in different triple negative breast cancer cells". Trabalho apresentado em 30th Porto Cancer Meeting - i3S, 2024.
  12. Pereira, A.C.; Parolo, C.; Ferreira, D.; Fernandes, R.; Soares, S.; Luis, C.; Rodrigues, L.R.; Sales, G.. "Citossensor eletroquímico para deteção de células tumorais circulantes". Trabalho apresentado em IPO Porto Summit, 2024.
  13. Andrade, R.G.D.; Ferreira, D.; Veloso, S.R.S.; Santos-Pereira, C.; Castanheira, E.M.S.; Côrte-Real, M.; Rodrigues, L.R.. "Magnetolipossomas carregados com lactoferrina para tratamento do cancro da mama". Trabalho apresentado em 5º Encontro Nacional de Jovens Investigadores em Oncologia - Liga Portuguesa Contra o Cancro Núcleo Regional do Norte, Portugal, 2023.
  14. Pereira, A.C. Santos-Pereira, C. Ferreira, D. Leite, B. Dias, A. Rodrigues, L.R.. "Exploring the potential of new 6-hydrazinopurine as effective anticancer agents". Trabalho apresentado em IV Chemical and Biological Engineering Doctoral Symposium, 2023.
  15. Andrade, R.G.D; Ferreira, D.; Veloso, S.R.S.; Santos-Pereira, C.; Castanheira, E.M.S.; Rodrigues, L.R.. "Unraveling the potential of lactoferrin-loaded magnetoliposomes for breast cancer therapy". Trabalho apresentado em IV Chemical and Biological Engineering Doctoral Symposium, 2023.
  16. Ferreira, D.; Rodrigues, L.R.. "The unlimited applications of aptamers". Trabalho apresentado em Ciência 2023 - Encontro com a Ciência e Tecnologia em Portugal, 2023.
  17. Pereira, A.C.; Santos-Pereira, C.; Ferreira, D.; Leite, B.; Dias, A.; Rodrigues, L.R.. "Unveiling the anticancer potential of 6-hydrazinopurines". Trabalho apresentado em 6º Simpósio em Química Medicinal, 2023.
  18. Carvalho, M.B.; Rodrigues, L.R.; Pereira, M.O.; Ferreira, D.; Sousa, A.M.. "Selection of specific aptamers for mucoid Pseudomonas aeruginosa biofilms developed in the airways of cystic fibrosis patients". Trabalho apresentado em 6º Simpósio em Química Medicinal, 2023.
  19. Ferreira, D.; Figueiredo, L.; Silva, C.; Osório, H.; Rodrigues, L.R.. "Unveiling novel triple negative breast cancer-associated biomarkers using an aptamer-based proteomic pipeline". Trabalho apresentado em Aptamers 2023, 2023.
  20. Ferreira, D.; Moreira, J.N.; Rodrigues, L.R.. "Surface engineering of exosomes led to an enhanced uptake by triple negative breast cancer cells". Trabalho apresentado em The 2nd International BioDesign Research Conference, 2021.
    10.12236/ibdrc2021-p-0047
  21. Sousa, D.A.; Tsogtbaatar, K.; Ferreira, D.; Tevlek, A.; Aydin, H.M.; Çelik, E.; Rodrigues, L.R.. "Generation and characterization of an osteosarcoma-targeting DNA aptamer". Trabalho apresentado em Oligonucleotide Technologies & Therapeutics @Portugal, 2021.
  22. Sande, M.G.; Ferreira, D.; Melo, L.D.R.; Silva, C.; Rodrigues, L.R.; Rodrigues, J.L.. "Selection and validation of DNA aptamers against Yersinia enterocolitica and Moraxella catarrhalis adhesins". Trabalho apresentado em Oligonucleotide Technologies & Therapeutics @Portugal, 2021.
  23. Ferreira, D.; Sousa, D.A.; Silva, C.; Melo, L.D.R.; Rodrigues, L.R.. "Identification of highly specific aptamers towards triple negative breast cancer". Trabalho apresentado em Oligonucleotide Technologies & Therapeutics @Portugal, 2021.
  24. Ferreira, D.; Costa, M.; Baltazar, F.; Kalluri, R.; Moreira, J.N.; Rodrigues, L.R.. "Engineered exosome-mediated delivery of RNAi therapeutics towards triple negative breast cancer therapy". Trabalho apresentado em EACR 2021 Congress - Innovative Science: Better Outcomes through Research, 2021.
  25. Ferreira, D.; Moreira, J.N.; Raghu, K.; Rodrigues, L.R.; Kalluri, R.. "Exosome-mediated delivery of MEK1-targeting siRNA towards triple negative breast cancer therapy". Trabalho apresentado em EuroNanoForum 2021, 2021.
  26. Ferreira, D.; Barbosa, J.; Silva, C.; Melo, L.D.R.; Rodrigues, L.R.; Barbosa.J.. "High-affinity aptamer ligands against triple negative breast cancer retrieved by high-throughput sequencing". Trabalho apresentado em BOD 2019 - Bioinformatic Open Days, 2019.
  27. Ferreira, D.; Moreira, J.N.; Rodrigues, L.R.. "Peptide mediated targeted delivery system towards triple negative breast cancer treatment". Trabalho apresentado em MIT Portugal Annual Conference 2018, 2018.
  28. Tavares, R.A.; Ferreira, D.; Rodrigues, L.R.. "Validation of a siRNA Targeting Gene Towards Colon Cancer Therapy". Trabalho apresentado em Cimago Meeting, 2018.
  29. Sousa, D.; Ferreira, D.; Rodrigues, L.R.; Sousa,D.. "In silico selection of an ssDNA aptamer against HER2-positive breast cancer cells using computational docking simulation". Trabalho apresentado em Microbiotec'17 - Congress of Microbiology and Biotechnology 2017, 2017.
  30. Sousa, D.; Ferreira, D.; Silva, A.C.; Kluskens, L.D.; Rodrigues, L.R.; Sousa,D.. "Selection of a molecule that specifically targets the cell-surface Human Epidermal growth factor receptor 2: in silico docking simulation". Trabalho apresentado em BOD 2017 - Bioinformatic Open Days, 2017.
  31. Ferreira, D.; Silva, V.L.; Nobrega, F.L.; Martins, I.M.; Rodrigues, L.R.; Kluskens, L.D.. "Identification of a novel peptide with high affinity towards breast cancer cells". Trabalho apresentado em Microbiotec'15 - Congress of Microbiology and Biotechnology 2015, 2015.
Resumo em conferência
  1. Novo, I.; Santos-Pereira, C.; Ligia, L.R.; Ferreira, D.. Autor correspondente: Ferreira, D.. "Exploring Lactoferrin-loaded Exosomes as a Novel Therapeutic Strategy for Colorectal Cancer". Trabalho apresentado em 6th meeting on medicinal biotechnology - School of Health of P.Porto, Porto, 2024.
    Aceite para publicação
  2. Gonçalves, C.; Rodrigues, L.R.; Ferreira, D.. Autor correspondente: Ferreira, D.. "Potential of exosome-mediated delivery of CRISPR-Cas9 for microRNA-155 targeting in triple negative breast cancer". Trabalho apresentado em 6th meeting on medicinal biotechnology - School of Health of P.Porto, Portugal, 2024.
    Aceite para publicação
  3. Ferreira, D.; Rodrigues, L.R.. Autor correspondente: Ferreira, D.. "Implications of MEK 1 silencing in different triple negative breast cancer cells". Trabalho apresentado em 30th Porto Cancer Meeting - i3S, Porto, 2024.
    Aceite para publicação
  4. Pereira, A.C.; Parolo, C.; Ferreira, D.; Fernandes, R.; Soares, S.; Luis, C.; Rodrigues, L.R.; Sales, G.. "Citossensor eletroquímico para deteção de células tumorais circulantes.". Trabalho apresentado em IPO Porto Summit, Porto, 2024.
    Aceite para publicação
  5. Ferreira, D.; Santos-Pereira, C.; Costa, M.; Afonso, J.; Longatto-Filho, A.; Baltazar, F.; Kalluri, R.; Moreira, J.N.; Rodrigues, L.R.. "Exosome-mediated MEK1 silencing is a promising approach against triple negative breast cancer regression". Trabalho apresentado em XIV Spanish-Portuguese Conference on Controlled Drug Delivery, Tenerife, 2022.
    Publicado
  6. Ferreira, D.; Santos-Pereira, C.; Costa, M.; Afonso, J.; Longatto-Filho, A.; Baltazar, F.; Kalluri, R.; Moreira, J.N.; Rodrigues, L.R.. "Exossomas modificados para o desenvolvimento de novas terapias para cancro de mama triplo negativo (Engineered exosomes for the development of novel therapies for triple negative breast cancer)". Trabalho apresentado em 3º Encontro Nacional de Jovens Investigadores em Oncologia, Porto, 2021.
    Publicado
  7. Sande, M.G.; Roque, L.; Marques, M.; Ferreira, D.; Rodrigues, J.L.; Braga, A.; Ramada, D.; Silva, C.; Rodrigues, L.R.. "Collagen-coated Magnetic Nanoparticles to Capture Pathogens". Trabalho apresentado em World Microbe Forum, online, 2021.
    Publicado
  8. Ferreira, D.; Moreira, J.N.; Kalluri, R.; Rodrigues, L.R.. "Peptide-mediated targeted delivery system towards triple negative breast cancer treatment". Trabalho apresentado em 1st Workshop online Latinoamericano en Nanobiotecnología - Aplicaciones en Agricultura, Medicina e Industria Textil, 2020.
    Publicado
  9. Sande, M.G.; Roque, L.; Marques, M.; Ferreira, D.; Rodrigues, J.L.; Braga, A.; Ramada, D.; Silva, C.; Rodrigues, L.R.. "Collagen-coated magnetic nanoparticles to capture pathogens from biological samples". Trabalho apresentado em 1st Workshop online Latinoamericano en Nanobiotecnología - Aplicaciones en Agricultura, Medicina e Industria Textil, 2020.
    Publicado
  10. Ferreira, D.; Moreira, J.N.; Rodrigues, L.R.. "Peptide mediated targeted delivery system towards triple negative breast cancer treatment". Trabalho apresentado em MIT Portugal Annual Conference 2018, Lisbon, 2018.
    Publicado
  11. Ferreira, D.; Silva, V.L.; Nobrega, F.L.; Martins, I.M.; Kluskens, L.D.; Rodrigues, L.R.. "Selection of Novel Peptides Homing Alternative Targets in Triple Negative Breast Cancer". Trabalho apresentado em BOD 2017 - Bioinformatic Open Days, Braga, 2017.
    Publicado
  12. Ferreira, D.; Silva, V.L.; Nobrega, F.L.; Martins, I.M.; Rodrigues, L.R.; Kluskens, L.D.. "Identification of a novel peptide with high affinity towards breast cancer cells". Trabalho apresentado em Microbiotec'15 - Congress of Microbiology and Biotechnology 2015, Évora, 2015.
    Publicado
  13. Ferreira, D.; Silva, A.; Baptista, D.; Nobrega, F.L.; Martins, I.M.; Kluskens, L.D.; Rodrigues, L.R.. "Rational identification of colorectal cancer homing peptides using phage display and in silico rigid-body docking studies of surface protein-ligand interactions". Trabalho apresentado em BOD 2015 - Bioinformatics Open Days, 9th to 10th April, Braga, 2015.
    Publicado
Tese / Dissertação
  1. "Peptide-mediated targeted delivery system towards triple negative breast cancer treatment". Doutoramento, Universidade do Minho Centro de Engenharia Biológica, 2021. https://hdl.handle.net/1822/75820.
  2. Ferreira, Débora. "Design of new strategies for breast cancer diagnosis". Mestrado, Universidade do Minho Centro de Engenharia Biológica, 2013. https://hdl.handle.net/1822/28632.
  3. Ferreira, Débora. "Construction of an inference system based on Fuzzy Logic paradigm to evaluate the fetal risk". Licenciatura, Instituto Politécnico de Bragança Escola Superior de Tecnologia e Gestão, 2011.

Propriedade Intelectual

Pedido provisório de patente
  1. 2021. "Isolated or synthetic DNA aptamer, methods and uses thereof (P1018.2 PP 2021.02.19)".
    Divulgado
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2024/11/15 Evaluation of the Cytotoxicity Profile of Prebiotic Biosurfactants Produced by Lactic Acid Bacteria for Dermal Applications XXVIII Encontro Galego Portugués de Química
(Vigo, Espanha)
2024/11/07 Harnessing Exosome-Mediated CRISPR-Cas9 delivery for targeting microRNA-155 in triple-negative breast cancer 5th edition of the Chemical and Biological Engineering Doctoral Symposium: Past, Present, Future
Centre of Biological Engineering (Braga, Portugal)
2024/09/24 Potencialização da lactoferrina bovina na terapia do cancro colorretal com recurso ao uso de exossomas 6º Encontro Nacional de Jovens Investigadores em Oncologia
Liga Portuguesa Contra o Cancro - Núcleo Regional do Norte (Porto, Portugal)
2024/07/02 Exploiting the role of miR-155 in triple negative breast cancer via CRISPR/Cas9 based genome editing The 48th FEBS Congress
Federation of European Biochemical Societies (Milan, Itália)
2024/06/13 Exosomes modified with anti-MEK1 siRNA lead to an effective silencing of triple negative breast cancer cells CEB's 30th anniversary
Centre of Biological Engineering - University of Minho (Braga, Portugal)
2024/06/12 Unlocking the Potential of Engineered Exosomes in Triple Negative Breast Cancer Therapy (Invited Flash Talk) 5th Digital Congress on Nanobiotechnology and Bioengineering (CDNB)
Laboratory of Nanobiotechnology (LNANO) of Embrapa Genetic Resources and Biotechnology (online, Brasil)
2024/06/11 Effects of photobiomodulation on chondrocytes as a strategy to regenerate knee cartilage LABBELS Meeting 2024
Centre of Biological Engineering - University of Minho (Braga, Portugal)
2024/05/27 Unlocking the potential of aptamers for cancer targeted therapies X IMFAHE’s International Conference – Innovation Camp – shaping the future through global learning and collaborations
IMFAHE (Online, Estados Unidos)
2024/03/21 Smart nanocarrier-based drug delivery systems for cancer therapy (Invited Lecture) BioJornadas 2024 - Bachelor Program in Biotechnology and Biomedical Engineering
Universidade Lusófona (online, Portugal)
2024/01/26 Citrate-coated manganese and calcium ferrite nanoparticles as potential magnetic hyperthermia agentes IX Clinical Biochemistry Workshop - University of Algarve
(Faro, Portugal)
2023/11/23 Super bio(partículas) no combate ao cancro CEB Talk2023
Fnac Braga (Braga, Portugal)
2023/05/23 Super vesículas no combate ao cancro Pint of Science 2023
(Braga, Portugal)
2022/01/27 Exosome-mediated MEK1 silencing is a promising approach against triple negative breast cancer regression XIV Spanish-Portuguese Conference on Controlled Drug Delivery
(online)
2021/11/14 Peptide-mediated targeted delivery system towards triple negative breast cancer treatment iCEBreak PhD edition - 8th session
2021/09/24 Exossomas modificados para o desenvolvimento de novas terapias para cancro de mama triplo negativo (Engineered exosomes for the development of novel therapies for triple negative breast cancer) 3º Encontro Nacional de Jovens Investigadores em Oncologia
Liga Portuguesa contra o cancro (Portugal)
2021/09/22 DNA aptamers towards Yersinia enterocolitica and Moraxella catarrhalis adhesins in novel POC diagnostics 2nd Chemical & Biological Engineering Doctoral Symposium
(Portugal)
2021/06/23 Collagen-coated Magnetic Nanoparticles to Capture Pathogens World Microbe Forum
(online)
2020/12/02 Peptide-mediated targeted delivery system towards triple negative breast cancer treatment 1st Workshop online Latinoamericano en Nanobiotecnología - Aplicaciones en Agricultura, Medicina e Industria Textil
(online)
2020/12/02 Collagen-coated magnetic nanoparticles to capture pathogens from biological samples 1st Workshop online Latinoamericano en Nanobiotecnología - Aplicaciones en Agricultura, Medicina e Industria Textil
(online)
2018/03/25 Characterization of a Biopolymer Produced by Arthrobacter viscosus CECT 908 for Application in Microbial Enhanced Oil Recovery OGWA 2018 - Society of Petroleum Engineers - SPE EOR Conference at Oil and Gas West Asia 2018
(Muscat, Omã)
2017/02/23 Selection of novel peptides homing alternative targets in triple negative breast cancer BOD 2017 - Bioinformatic Open Days
(Braga, Portugal)
2015/04/09 Rational identification of colorectal cancer homing peptides using phage display and in silico rigid-body docking studies of surface protein-ligand interactions BOD 2015 - Bioinformatics Open Days
(Braga, Portugal)

Orientação

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2024/09 - Atual Novel Therapeutic Options for Chemotherapy-resistant Triple Negative Breast Cancer
Orientador de Mariana Sousa (Co-supervisor: Ligia Rodrigues)
 Biomedical Engineering (Mestrado)
Universidade do Minho Centro de Engenharia Biológica, Portugal
2024/09 - Atual Extracellular vesicle-mediated drug delivery in triple negative breast cancer
Orientador de Leonor Gandarela (Co-supervisor: Ligia Rodrigues)
 Biotecnology (Mestrado)
Universidade do Minho Centro de Engenharia Biológica, Portugal
2024/09 - Atual Development of new approaches to breast cancer treatment
Orientador de Clara Gonçalves
 Biomedical Engineering (Mestrado)
Universidade do Minho Centro de Engenharia Biológica, Portugal
2024/01/01 - Atual Control of salmonellosis, in the poultry industry, employing nanoencapsulated aptamers of nucleic acid mimics
Coorientador de Inês Santos
 Chemical and Biological Engineering (Doutoramento)
Universidade do Minho Centro de Engenharia Biológica, Portugal
2023/09 - 2024/11 Cell-derived extracellular vesicles as a delEVery platform towards triple negative breast cancer
Coorientador de Catarina Gonçalves (Supervisor: Ligia Rodrigues)
 Biotecnology (Mestrado)
Universidade do Minho, Portugal
2023/09 - 2024/11 Lactoferrin-loaded extracellular vesicles for triple negative breast cancer therapy
Coorientador de Inês Novo (Supervisor: Ligia Rodrigues)
 Biomedical Engineering (Mestrado)
Universidade do Minho, Portugal
2024/02/01 - 2024/06/26 Exosomes loaded with lactoferrin for treating triple negative breast cancer
Orientador de Ana Josefina Reinolds
 Project in Biochemistry (Licenciatura/Bacharelato)
Universidade do Minho, Portugal
2024/02/20 - 2024/06/19 Identification of novel breast cancer-related biomarkers through an aptamer-based proteomic approach
Orientador de Beatriz Santos (Co-supervisor: Sergio Sousa)
 Project in Bioinformatics - Master in Bioinformatics (Mestrado)
Universidade do Minho, Portugal
2022/10 - 2023/10 Development of an Artificial intelligence Breast Cancer diagnostic tool
Coorientador de Rute Castro (Supervisor: Oscar Dias)
 Bioinformatics (Mestrado)
Universidade do Minho, Portugal
2022/10 - 2023/10 The use of Genome scale metabolic modelling of triple negative breast cancer to identify possible new drug targets
Coorientador de Mariana Gonçalves (Supervisor: Oscar Dias)
 Bioinformatics (Mestrado)
Universidade do Minho, Portugal
2022/09 - 2023/10 Use of an engineered exosome-like delivery platform towards colorectal cancer therapy
Orientador de Henrique Fontes (Co-supervisor: Andreia Gomes)
 Molecular Genetics (Mestrado)
Universidade do Minho, Portugal
2022/09 - 2023 Aptamer-targeted for Pseudomonas aeruginosa biofilms formed in cystic fibrosis airways for early diagnosis
Coorientador de Beatriz Carvalho (Supervisor: Ana Margarida Sousa)
 Biomedical Engineering (Mestrado)
Universidade do Minho, Portugal
2022/02 - 2022/07 Unravelling Synthetic lethal interactions in breast cancer for personalized medicine
Coorientador de Rute Castro and Mariana Gonçalves (Supervisor: Oscar Dias)
 Project in Bioinformatics - Master in Bioinformatics (Mestrado)
Universidade do Minho, Portugal

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação) 		Instituição / Organização
2021 - 2021 Member of the organizing committee of the Festival Pint of Science 2021 (2021/05 - 2021/05)
Festival (Membro da Comissão Organizadora)
 Universidade do Minho, Portugal
2020 - 2020 Member of the organizing committee of the Festival Pint of Science 2020 (2020/05 - 2020/05)
Festival (Membro da Comissão Organizadora)
 Universidade do Minho, Portugal
2019/06 - 2019/06 Member of the organizing committee of the practical session Phage Display Technology of the 4th International hands-on Phage Biotechnology Course (2019/06 - 2019/06)
Oficina (workshop) (Membro da Comissão Organizadora)
 Universidade do Minho Centro de Engenharia Biológica, Portugal
2019/05 - 2019/05 Member of the organizing committee of the Festival Pint of Science 2019 (2019/05 - 2019/05)
Festival (Membro da Comissão Organizadora)
 Universidade do Minho, Portugal
2017/06 - 2017/06 Member of the organizing committee of the practical session Phage Display Technology of the 3rd International hands-on Phage Biotechnology Course (2017/06 - 2017/06)
Oficina (workshop) (Membro da Comissão Organizadora)
 Universidade do Minho Centro de Engenharia Biológica, Portugal
2015/06 - 2015/06 Member of the organizing committee of the practical session Phage Display Technology of the 2nd International hands-on Phage Biotechnology Course (2015/06 - 2015/06)
Oficina (workshop) (Membro da Comissão Organizadora)
 Universidade do Minho Centro de Engenharia Biológica, Portugal

Participação em evento

Descrição da atividade
Tipo de evento 		Nome do evento
Instituição / Organização
2025/02/06 - Atual Chair of the Student Network on Extracellular Vesicles (SNEV) Translational EV Series Talk: "When Polymers Meet EVs: interest of EVs’ Surface Modification with PEG Alternatives for in vivo Administration" by Dr. Marie Morille. Event webpage: https://snevresearch.wordpress.com/events-organized-by-snev/
Seminário
 SNEV Translational EV Series
2025/01/16 - Atual Chair of the Student Network on Extracellular Vesicles (SNEV) EV Technology Series Talk: "Bioengineered exosomes for targeted delivery of RNA therapeutics" by Dr. Samir EL Andaloussi. Event webpage: https://snevresearch.wordpress.com/events-organized-by-snev/
Seminário
 SNEV EV Technology Series
2024/11/20 - 2024/11/20 Instructor in the event "CEB em exposição"
Exposição
 Science and Technology Week 2024
Universidade do Minho Centro de Engenharia Biológica, Portugal
2024/09/29 - 2024/09/29 Instructor in European Researchers Night 2024 - Industrial Biotechnology at CEB: Extreme microorganisms in action for sustainable fashion (Noite Europeia dos Investigadores 2024 - Biotecnologia Industrial no CEB: Microrganismos extremos em ação para uma moda sustentável). Altice Forum Braga, Braga, Portugal
Exposição
 European Researcher's Night 2024
Universidade do Minho Centro de Engenharia Biológica, Portugal
2024/06/11 - 2024/06/20 Participant in "Escola de Verão de Ciência Aberta 2024"
Oficina (workshop)
Universidade do Minho, Portugal
2024/04/29 - 2024/04/29 Instructor - Scientist for a day with the activity "Cloning protocol - The green Sherlock Holmes"
Oficina (workshop)
 Scientist for a day
Universidade do Minho Centro de Engenharia Biológica, Portugal
2024/01/29 - 2024/02/14 Participant in Workshops: AI and Innovation in High Education by Borja Santos Porras (January 29); Peer Mentoring Primer - by Joanne Kamens (February 14). Online
Oficina (workshop)
 iPDP-International Professional Development Program
IMFAHE (International Mentoring Foundation for the Advancement of Higher Education), Estados Unidos
2024/02/02 - 2024/02/02 Participant in Workshop on Successful Supervisor-Student Meetings (Reuniões de Orientação Eficazes) by Dr Ana Salgado and MSc Ana Freitas (3 h)
Oficina (workshop)
 Workshop on Successful Supervisor-Student Meetings
Doctoral College of University of Minho, Portugal
2024/02/02 - 2024/02/02 Participant in Workshop on Time Management and Personal Organization of PhD Students (Workshop sobre Gestão do Tempo e Organização Pessoal dos Doutorandos) by Dr Ana Salgado and MSc Ana Freitas (3 h)
Oficina (workshop)
 Workshop on Time Management and Personal Organization of PhD Students
Doctoral College of University of Minho, Portugal
2024/01 - 2024/02 Participant in Workshops: How do I start a business? Create a Business Plan - by Javier Aguera (January 18); How to fund your business idea - by Jonathan Thon, PhD (February 1); Patent your ideas. Protect your inventions - by Marta Lage (February 8). From Academia to Entrepreneurship - by David Lagares (February 15). Online. Workshop
Oficina (workshop)
 IMFAHE From Academia to Entrepreneurship - Quarter Course 2 on Innovation, Entrepreneurship and Leadership
IMFAHE (International Mentoring Foundation for the Advancement of Higher Education), Estados Unidos
2024/01/25 - 2024/01/25 Participant in the Masterclass "Comunicação em Reuniões"
Oficina (workshop)
 Speak and Lead, Portugal
2024/01/25 - 2024/01/25 Participant in Workshop on Good Practices in Doctoral Orientation (Workshop sobre Boas Práticas na Orientação Doutoral) by Dr Ana Salgado and MSc Ana Freitas (7 h)
Oficina (workshop)
 Workshop on Good Practices in Doctoral Orientation
Doctoral College of University of Minho, Portugal
2023/12/01 - 2023/12/01 Participant in IMFAHE 2023-2024 workshop: Keynote Speech: 'Generation Z Uncovered: Bridging the Teaching Gap Between TikTok and Textbooks' by Gabriela Lagreca, December 1. Online
Oficina (workshop)
 iPDP-International Professional Development Program
IMFAHE (International Mentoring Foundation for the Advancement of Higher Education), Estados Unidos
2023/09/29 - 2023/09/29 Instructor in European Researcher's Night 2023 - Industrial Biotechnology at CEB: research to achieve industrial sustainability. (Altice Forum Braga, Braga, Portugal)
Exposição
 European Researcher's Night 2023
Universidade do Minho Centro de Engenharia Biológica, Portugal
2023/09/22 - 2023/09/22 Participant in the event "5º Encontro Nacional de Jovens Investigadores em Oncologia"
Conferência
 Liga Portuguesa Contra o Cancro Núcleo Regional do Norte, Portugal
2023/07/12 - 2023/07/14 Participant in the Advanced Workshop on Flow Cytometry for Microbial Samples
Oficina (workshop)
Universidade do Minho Centro de Engenharia Biológica, Portugal
2023/06/19 - 2023/06/23 Instructor of the practical session Phage Display Technology
Oficina (workshop)
 5th International hands-on Phage Biotechnology Course
Universidade do Minho Centro de Engenharia Biológica, Portugal
2022/09/29 - 2022/09/29 Instructor in European Researcher's Night 2022 - Industrial Biotechnology at CEB: research to achieve industrial sustainability
Exposição
 European Researcher's Night 2022
Universidade do Minho, Portugal
2022/09/24 - 2022/09/24 Participant in the event "4º Encontro Nacional de Jovens Investigadores em Oncologia"
Conferência
 4º Encontro Nacional de Jovens Investigadores em Oncologia
Liga Portuguesa Contra o Cancro Núcleo Regional do Norte, Portugal
2022/05/12 - 2022/05/13 Participant in the event "PORTO CANCER MEETING - Extracellular Vesicles, Cell Communication and Cancer Time to Prick the Bubble"
Conferência
 PORTO CANCER MEETING
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2022/04/07 - 2022/04/09 Instructor UPA - UMinho Portas Abertas 2022
Exposição
Universidade do Minho, Portugal
2022/02/09 - 2022/02/09 Participant in the webinar "TIPS for applying to CEEC 5th edition 2022"
Oficina (workshop)
 TIPS for applying to CEEC 5th edition 2022
LYRIS - Advanced Science Educarion, Portugal
2021/11/27 - 2021/11/27 Instructor CEB Open Day - Semana da Ciência e Tecnologia 2021
Exposição
Universidade do Minho Centro de Engenharia Biológica, Portugal
2021/05/09 - 2021/05/09 Participant in the event "Lipidomics In Health & Disease"
Oficina (workshop)
 9th Workshop in Lipidomics
Universidade de Aveiro, Portugal
2020/04 - 2020/12 Volunteer on the execution of SARS-Cov-2 detection tests
Outro
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2020/01/15 - 2020/02/06 Participant in the module of "National (and European) Legislation"
Oficina (workshop)
 15th Laboratory Animal Science course
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2019/06/21 - 2019/06/21 Instructor of the practical session Phage Display Technology
Oficina (workshop)
 4th International hands-on Phage Biotechnology Course
Universidade do Minho Centro de Engenharia Biológica, Portugal
2019/02/01 - 2019/03/02 Participant in the Laboratory Animal Science course
Oficina (workshop)
University of Texas MD Anderson Cancer Center, Estados Unidos
2019/02/25 - 2019/02/25 Participant in the 2nd Annual Symposium on Pancreatic Cancer
Simpósio
University of Texas MD Anderson Cancer Center, Estados Unidos
2018/03/27 - 2018/03/28 Instructor in the Program the Best Students at UMinho 2018- National Edition "Engenharia Química e Biológica - uma inspiração para o teu futuro"
Oficina (workshop)
 Program the Best Students at UMinho 2021- National Edition
Universidade do Minho Centro de Engenharia Biológica, Portugal
2018/01 - 2018/01 Introduction to Synthetic Biology: Tools, methods and containment systems (Invited Lecture) Lecture - Master Program in Biotechnological Engineering
Instituto Politécnico de Bragança Escola Superior Agrária, Portugal
2017/09/19 - 2017/09/21 Participant in the post-graduated course - Introduction to digital image analysis with ImageJ /Fiji Course
Oficina (workshop)
 Introduction to digital image analysis with ImageJ /Fiji Course
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2017/06/23 - 2017/06/23 Instructor of the practical session Phage Display Technology
Oficina (workshop)
 3rd International hands-on Phage Biotechnology Course
Universidade do Minho Centro de Engenharia Biológica, Portugal
2017/06/19 - 2017/06/20 Participant in Process parameters and kinetics, Process design and simulation with commercial software
Oficina (workshop)
 MATLAB, SuperPro Designer and Solver Workshop
Universidade do Minho, Portugal

Universidade de Vigo, Espanha
2015/07/21 - 2015/07/24 Participant in the post-graduated course - Cancer Therapy: from basic research to clinic
Oficina (workshop)
 Cancer Therapy: from basic research to clinic
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
2015/06/21 - 2015/06/21 Instructor of the practical session Phage Display Technology
Oficina (workshop)
 2nd International hands-on Phage Biotechnology Course
Universidade do Minho Centro de Engenharia Biológica, Portugal

Júri de grau académico

Tema
Tipo de participação 		Nome do candidato (Tipo de grau)
Instituição / Organização
2024/12/18 Aptamers for bloking F18+ enterotoxigenic Escherichia coli
Arguente principal
 Ana Campos (Mestrado)
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
2024/11/29 Phage Display for the development of bacteriophages to detect Alzheimer´s disease
Arguente principal
 Gonçalo Reis (Mestrado)
Universidade do Minho Centro de Engenharia Biológica, Portugal
2024/11/22 Hyaluronic acid-modified selenium nanoparticles for cancer therapy
Arguente principal
 Beatriz Braga (Mestrado)
Universidade do Minho Centro de Engenharia Biológica, Portugal
2024/11/08 Designing in-silico aptamers for potential use in marine bioremediation
Arguente principal
 Rafael Vieira (Mestrado)
Universidade do Porto, Portugal
2024/10/11 Microbial Infections: Essential oils as an alternative treatment for Candida spp. biofilms in presence of Lactobacillus spp.
Arguente principal
 Inês Silva (Mestrado)
Universidade do Minho Centro de Engenharia Biológica, Portugal
2024/06/26 Exosomes loaded with lactoferrin for treating colorectal cancer
Orientador
 Ana Josefina Vieria Reinolds (Outro)
Universidade do Minho Escola de Ciências, Portugal
2024/03/25 Exploiting novel options for triple-negative breast cancer treatment: combination studies of classical therapeutics with the chromene derivarive SMT01
Arguente principal
 Maria Dolores Mendes Borges (Mestrado)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2023/12/13 Development of an Artificial intelligence Breast Cancer diagnostic tool
Orientador
 Rute Castro (Mestrado)
Universidade do Minho, Portugal
2023/11/29 Use of an engineered exosome-like delivery platform towards colorectal cancer therapy
Orientador
 Henrique Fontes (Mestrado)
Universidade do Minho, Portugal
2023/10/12 Preparation and characterization of light-sensitive nanoparticles for cancer therapy
Arguente principal
 Catarina Rodrigues (Mestrado)
Universidade do Minho Centro de Engenharia Biológica, Portugal

Arbitragem científica em conferência

Nome da conferência Local da conferência
2024/11/07 - 2024/11/08 5th Chemical and BioEngineering Doctoral Symposium University of Minho

Arbitragem científica em revista

Nome da revista (ISSN) Editora
2022/01 - Atual Bioengineering (Special Issue Editor of "Bio-Applications of engineered Escherichia coli", Guest Co-Editor: Joana L. Rodrigues (CEB-UM)) (2306-5354) MDPI
2022/10 - 2023/12 International Journal of Molecular Sciences (Special Issue Editor of "Nanomaterials/Nanocarriers for Drug Delivery for Application in Cancer Therapy", Guest Co-Editor: Lígia R. Rodrigues (CEB-UM)) (2296-4185) MDPI
2022/09 - 2023/12 International Journal of Molecular Sciences (Special Issue Editor of "Recent Advances in Biosurfactants", Guest Co-Editors: Lígia R. Rodrigues and Cátia Santos-Pereira (CEB-UM)) MDPI

Comissão de avaliação

Descrição da atividade
Tipo de assessoria 		Instituição / Organização Entidade financiadora
2022/01 - 2022/07 Member of the evaluators panel for the attribution of exceptional grants for mitigating the impacts of COVID-19 on research activities
Avaliador
 Fundação para a Ciência e a Tecnologia, Portugal Fundação para a Ciência e a Tecnologia

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2025/02 - Atual Innovation and bio-based companies (Theoretical and Pratical classes) Engenharia Química e Biológica, Ciência dos Alimentos, (Mestrado integrado) Universidade do Minho Departamento de Engenharia Biológica, Portugal
2024/09 - 2025/01 Innovation and Business Creation in Bioengineering (Theoretical and Pratical classes) Biomedical Engineering and Bioinformatics (Mestrado) Universidade do Minho Departamento de Engenharia Biológica, Portugal
2024/02 - 2024/06 Innovation and bio-based companies (Practical classes) Chemical and Biological Engineering - Biotechnology (Mestrado) Universidade do Minho Departamento de Engenharia Biológica, Portugal
2024/02 - 2024/06 Instrumental methods and Data analysis (Practical classes) Chemical and Biological Engineering (Licenciatura) Universidade do Minho Departamento de Engenharia Biológica, Portugal
2023/09 - 2024/02 Innovation and Business Creation in Bioengineering (Practical classes) Biomedical Engineering (Mestrado) Universidade do Minho Departamento de Engenharia Biológica, Portugal

Entrevista (jornal / revista)

Descrição da atividade Jornal / Forum
2025/01 EMBO Poster Prize presenting "Engineering extracellular vesicles for enhanced cancer-targeted therapeutic cargo delivery" at the 5th Next-Generation Synthetic Biology conference MaisGuimarães
2021/12/10 Selection of a new peptide with affinity for breast cancer ASPIC - Associação Portuguesa de Investigação em Cancro
2021/02/22 Oncology Research grant attributed by Liga Portuguesa contra o cancro https://twitter.com/EngBiologicaUM/status/1363919692587532288
2021/02/19 Portuguese women in science O Louzadense
2016/11/10 Selection of Novel Peptides Homing the 4T1 Cell Line: Exploring Alternative Targets for Triple Negative Breast Cancer ASPIC - Associação Portuguesa de Investigação em Cancro

Entrevista / Programa (rádio / tv)

Programa Tema
2025/01/08 - Atual Rádio Vizela - Programa Especial Informação About the EMBO Poster Prize presentation on 'Engineering Extracellular Vesicles for Enhanced Cancer-Targeted Therapeutic Cargo Delivery' at the 5th Next-Generation Synthetic Biology Conference in Belgium.
2023/12/12 - 2023/12/12 Porto Canal - Rubrica "Portugal Inovador" no programa Manhã Informativa Super vesículas no combate ao cancro
2022/07/23 - 2022/07/23 Rádio Vizela - Programa Especial Informação Work developed under the scope of my PhD project - Development of novel strategies for the treatment of triple negative breast cancer

Expedição científica

Descrição da atividade Instituição / Organização
2019/02 - 2019/08 Visiting Student at Kaluri's Lab during PhD - Supervised by Raghu Kalluri University of Texas MD Anderson Cancer Center, Estados Unidos

Membro de associação

Nome da associação Tipo de participação
2024/09/30 - Atual European Association for Cancer Research (EACR) Embassador
2024/09/01 - Atual Student Network on Extracellular Vesicles (SNEV) Newsletter team (Manager)
2024/02/01 - Atual Associação Portuguesa de Investigação em Cancro (ASPIC) Member
2024/02/01 - Atual Portuguese Biochemical Society Member
2024/02 - Atual European Association for Cancer Research (EACR) Member
2023/06 - Atual Portuguese network on extracellular vesicles (PNEV) Member
2022/01 - Atual Spanish-Portuguese Local Chapter of the Controlled Release Society (SPLC-CRS) Member
2020/02 - 2021/12 EACR - European Association for Cancer Research Member

Membro de comissão

Descrição da atividade
Tipo de participação 		Instituição / Organização
2024/07/03 - 2024/07/05 Organization of the session: "The role of biotechnology in healthcare" - Encontro Ciência 2024
Membro
 Fundação para a Ciência e a Tecnologia, Portugal

Outro júri / avaliação

Descrição da atividade Instituição / Organização
2024/09/11 - 2024/10/13 Reviewer of a project for the National Science Centre Poland. Funding scheme: OPUS 27 and Panel: NZ6 (Human and animal immunology and infection) Narodowe Centrum Nauki, Polónia
2024/10 - 2024/10 Member of the jury in the selection of a master's candidate for the available position (CEB-BI-30-2024), funded by Portuguese funds through FCT - Fundação para a Ciência e a Tecnologia, within the scope of the R&D project B3iS - Biodiversity and Bioprospecting of Biosurfactants in Saline Environments (Ref. FCT PTDC/BII-BIO/5554/2020) Universidade do Minho Centro de Engenharia Biológica, Portugal
2024/05/27 - 2024/05/27 Member of the evaluation committee of the Best Oral Presentation Session at X IMFAHE International Conference – Innovation Camp - Shaping the future through global learning and collaborations, 27th May (online)
2024/03 - 2024/03 Member of the jury in the selection of a master's candidate for the available position (CEB-BI-19-2024), funded by Portuguese funds through FCT - Fundação para a Ciência e a Tecnologia, I.P., under the Pluriannual Financing Programme for R&D Units for the Centre of Biological Engineering of University of Minho (ref. UIDB/BIO/04469/2020) Universidade do Minho Centro de Engenharia Biológica, Portugal
2018/12/10 - 2018/12/10 Member of the evaluators pannel of Innovation and Entrepreneurship in Biotechnology projects from the Doctoral Programme in Biological Engineering, Integrated Master in Biological Engineering and Masters in Biotechnology and Bioinformatics Universidade do Minho Centro de Engenharia Biológica, Portugal

Revisão ad hoc de artigos em revista

Nome da revista (ISSN) Editora
2024/06 - Atual Journal of Controlled Release Elsevier
2024/06 - Atual Frontiers in Molecular Biosciences Frontiers
2023 - Atual ACS Omega ACS Publications
2022 - Atual Pharmaceutics MDPI
2022 - Atual Journal of Drug Delivery Science and Technology Elsevier
2021 - Atual International Journal of Molecular Sciences MDPI
2021 - Atual Biomolecules MDPI

Tutoria

Tópico Nome do aluno
2024/03 - Atual Development of a drug carrier nanosystem for a new anticancer drug and optimization of the new drug Sofia Teixeira, PhD student
2023/01 - Atual Development of an electro-mechanical stimuli device to regenerate knee cartilage Sofia Oliveira, PhD student
2022/10/01 - Atual Functionalized magnetoliposomes for enhanced anticancer activity of lactoferrin against triple negative breast cancer cells Raquel Andrade, PhD student
2024/06/01 - 2024/10/31 Evaluation of cello-oligosaccharides prebiotic potential in 3D skin models Ana Catarina Pereira, Research Fellow
2024/06/17 - 2024/07/26 Assessment of the biological activity of biotechnologically produced biosurfactants extracts using lactic acid bacteria Andrea Martínez Arcos, PhD student
2023/10/18 - 2023/10/18 Speed Mentoring UMinho UMinho PhD Students
2022/09 - 2023/10 Lactoferrin-loaded extracellular vesicles as a strategy against triple negative breast cancer Rita Barros, MSc Student
2022/09 - 2023/10 In vitro assessment and mechanism of action of novel purine derivatives as anticancer agents Ana Pereira, MSc Student
2022/09 - 2023/10 Unveiling the role of iron metabolism in lactoferrin anticancer activity Tayane Fontes, MSc Student
2019/07 - 2022/12 Multifunctional materials to capture pathogens from biological samples Maria Georgina Sande, PhD Student - Vibrant Project (H2020-MSCAITN-2017_765042))
2018/03 - 2022/12 Targeting oncogenic microRNAs in triple negative breast cancer using a CRISPR-cas9 based approach Diana Sousa, PhD student
2021/09 - 2022/10 Mechanisms of action of novel 6-substituted purines as anticancer agents Marta Machado, MSc Student
2022/06 - 2022/07 Isolation of exosome-like nanovesicles from citrus Mariana Gonçalves, MSc Student - volunteering provided by Biological Engineering Student Association
2021/09 - 2022/05 Identification of cell surface receptors specifically targeted by aptamers raised against triple negative breast cancer Laura Figueiredo, MSc Student
2020/09 - 2022/01 Validation of a novel delivery system towards breast cancer therapy Renata Silva, MSc Student
2020/09 - 2022/01 Evaluation of biosynthetic curcumin cytotoxicity and anticancer activity Mariana Azeredo, MSc Student
2017/10 - 2021/10 Development of a biosensor for detection of cancer biomarkers Ana Cláudia Pereira - PhD Student
2020/01 - 2020/02 Protein-based magnetic nanoparticles for bacterial capture Márcia Marques, MSc Student - Internship Vibrant project (H2020-MSCAITN-2017_765042)
2017/09/01 - 2018/09/01 Development of an aptamer-based nanoparticle towards breast cancer Cátia Silva, MSc Student
2017/09/01 - 2018/07/14 Validation of siRNAs against MAP2K1/MEK1 towards colon cancer therapy Ana Carvalho, MSc Student
2017/09 - 2018/07 Validation of a siRNA Targeting PI3KCA towards Colorectal Cancer Therapy Rute Tavares, MSc Student
2018/01 - 2018/05 Selection and Validation of aptamers against Osteosarcoma by cell-SELEX method Khaliunsarnai Tsogtbaatar, MSc Student
2015/09/01 - 2016/10/31 Genetic modification of a bacteriophage to create a multifunctional drug delivery particle Adriana Lima, MSc Student
2015/09/01 - 2016/10/15 Design and validation of siRNAs against the mTOR gene towards breast cancer therapy Diana Sousa, MSc Student
2015/09 - 2016/10 Engineering of specific bacteriophages for early diagnosis of Alzheimer´s disease Ana Isabel Silva, MSc Student
2014/01 - 2015/01 Selection of specific colon cancer tumor peptides from combinatorial phage libraries Ana Paula Silva, MSc Student
Distinções

Prémio

2024 FEBS Bursary Grant for participation in the 48th FEBS Congress 2024, 29th June - 3rd July, Milan, Italy
2024 Best oral presentation award 2024 presenting "Unlocking the potential of aptamers for cancer targeted therapies" at the X IMFAHE’s International Conference – Innovation Camp – shaping the future through global learning and collaborations, 27th May
2024 Best Poster award presenting "Citossensor eletroquímico para deteção de células tumorais circulantes" in the Basic and Translational Research panel at the IPO Porto Summit, 9-11th May
2024 Best Poster award presenting "Influence of therapeutic ultrasound on human chondrocytes to treat cartilage degeneration" at LABBELS Meeting, 11th June
2024 Honorable mention in the CEB Scientific Publication Award with the paper "Exosomes modified with anti-MEK1 siRNA lead to an effective silencing of triple negative breast cancer cells""
2024 EMBO Poster Prize presenting "Engineering extracellular vesicles for enhanced cancer-targeted therapeutic cargo delivery" at the 5th Next-Generation Synthetic Biology conference (Belgium), 11-12th December
European Molecular Biology Laboratory, Alemanha
2022 Personal tribute
Junta de Freguesia de Moreira de Cónegos, Portugal
2021 Third prize for best poster presenting "Surface engineering of exosomes led to an enhanced uptake by triple negative breast cancer cells"
The 2nd International BioDesign Research Conference, Estados Unidos
2021 Liga Portuguesa contra o cancro 2021 fellowship with the project "Engineered exosome-mimetic nanovesicles as drug delivery systems in triple negative breast cancer"
Liga Portuguesa Contra o Cancro Núcleo Regional do Norte, Portugal

Outra distinção

2023 Selected to participate as a professor/researcher in the IMFAHE’s Platform of Talent 2023-2024 promoted by IMFAHE (International Mentoring Foundation for the Advancement of Higher Education)
2022 Individual Call to Scientific Employment Stimulus - 5th Edition (2022.01681.CEECIND)
Fundação para a Ciência e a Tecnologia, Portugal
2016 PhD Fellowship MIT-Portugal Program
Massachusetts Institute of Technology MIT Portugal Program, Portugal